国家对捐赠卵子体外受精(IVF)周期的强制性财务覆盖对从不育捐赠者、付费捐赠者和冷冻卵子库中选择新鲜卵子的影响

L. Zalles, Kyle Le, J. Check, C. Wilson, D. Summers, J. Choe
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引用次数: 0

摘要

我们试图确定使用不育卵母细胞供者将收集到的卵子的一半捐赠给受体,与从单一受体的补偿供者获得的卵母细胞相比,在新鲜和冷冻胚胎移植(ET)后的活产率是否相当,补偿供者分为两个受体,或一个卵母细胞库。回顾性分析了1361例体外受精-胚胎移植(IVF-ET)周期,比较了新鲜体外受精后的活产率和供体卵母细胞来源每次提取的活产率。每个新鲜ET的活产率在四个卵母细胞来源之间没有显着差异。然而,与使用两个受者或卵母细胞库之间的补偿供者相比,使用不育供者的每次检索活产率有统计学上的显著增加。与使用单一受体的补偿供体相比,使用不育供体的每次检索的活产率降低了15%。不孕不育服务的经济负担一直是不孕不育治疗的长期障碍。与不孕捐赠者共享卵母细胞可以在不牺牲成功率的情况下获得经济优势。对于那些在强制州接受试管婴儿的人来说,这尤其节省了成本,因为他们实际上在经济上报销了试管婴儿周期的大部分费用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The Impact of State Mandated Financial Coverage for Donor Egg In Vitro Fertilization (IVF) Cycles on Choosing Fresh Eggs from Infertile Donor vs. Paid Donors vs. Frozen Egg Banks
We sought to determine if using infertile oocyte donors donating only half of the eggs collected to recipients, had comparable live delivery rates following fresh and frozen embryo transfer (ET) when compared to oocytes obtained from compensated donors with a single recipient, compensated donors split between two recipients, or an oocyte bank. A retrospective review of 1,361 in vitro fertilization-embryo transfer (IVF-ET) cycles comparing live delivery rates after fresh ET and live delivery rates per retrieval by donor oocyte source was performed. Live delivery rates per fresh ET showed no significant difference between the four-oocyte sources. However, using an infertile donor had a statistically significant increase in live delivery rate per retrieval when compared to using a compensated donor split between two recipients or an oocyte bank. There was a 15% decrease in live delivery rate per retrieval when using an infertile donor compared to a compensated donor with a single recipient. Financial burden of infertility services has been a long-standing barrier to infertility treatment access. Sharing oocytes with an infertile donor can have financial advantage without significant sacrifice of success rates. It is especially cost saving for recipients in mandated states who actually are financially reimbursed for the majority of the cost of the IVF cycle.
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