Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia最新文献_第7页

An image of a FGF-23-producing tumor resulting in osteomalacia. 产生 FGF-23 的肿瘤导致骨软化症的图像。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-06-24 eCollection Date: 2024-10-01 DOI: 10.1590/2175-8239-JBN-2023-0207en

Marcelo Giacomini Louça, Ana Laura Mendes, Rodrigo Bueno de Oliveira

引用次数: 0

Association between chronic kidney disease stages and changes in ambulatory blood pressure monitoring parameters. 慢性肾脏病分期与动态血压监测参数变化之间的关系。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-06-17 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2023-0066en

André Murad Nagahama, Vanessa Dos Santos Silva, Vanessa Burgugi Banin, Roberto Jorge da Silva Franco, Pasqual Barretti, Silmeia Garcia Zanati Bazan, Luis Cuadrado Martin

{"title":"Association between chronic kidney disease stages and changes in ambulatory blood pressure monitoring parameters.","authors":"André Murad Nagahama, Vanessa Dos Santos Silva, Vanessa Burgugi Banin, Roberto Jorge da Silva Franco, Pasqual Barretti, Silmeia Garcia Zanati Bazan, Luis Cuadrado Martin","doi":"10.1590/2175-8239-JBN-2023-0066en","DOIUrl":"10.1590/2175-8239-JBN-2023-0066en","url":null,"abstract":"Introduction: Blood pressure (BP) assessment affects the management of arterial hypertension (AH) in chronic kidney disease (CKD). CKD patients have specific patterns of BP behavior during ambulatory blood pressure monitoring (ABPM).Objectives: The aim of the current study was to evaluate the associations between progressive stages of CKD and changes in ABPM.Methodology: This is a cross-sectional study with 851 patients treated in outpatient clinics of a university hospital who underwent ABPM examination from January 2004 to February 2012 in order to assess the presence and control of AH. The outcomes considered were the ABPM parameters. The variable of interest was CKD staging. Confounding factors included age, sex, body mass index, smoking, cause of CKD, and use of antihypertensive drugs.Results: Systolic BP (SBP) was associated with CKD stages 3b and 5, irrespective of confounding variables. Pulse pressure was only associated with stage 5. The SBP coefficient of variation was progressively associated with stages 3a, 4 and 5, while the diastolic blood pressure (DBP) coefficient of variation showed no association. SBP reduction was associated with stages 2, 4 and 5, and the decline in DBP with stages 4 and 5. Other ABPM parameters showed no association with CKD stages after adjustments.Conclusion: Advanced stages of CKD were associated with lower nocturnal dipping and greater variability in blood pressure.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230066"},"PeriodicalIF":1.3,"publicationDate":"2024-06-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11205976/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141419175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Charting the future of kidney care in Brazil: insights and evolution through the Brazilian Dialysis Survey. 描绘巴西肾脏护理的未来：巴西透析调查的启示与演变。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-05-24 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2024-E006en

Roberto Pecoits Filho

引用次数: 0

Flow problems during implantation of a peritoneal dialysis catheter: building a capnoperitoneum using the peritoneal dialysis catheter. 腹膜透析导管植入过程中的血流问题：使用腹膜透析导管建立腹膜帽。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-05-24 eCollection Date: 2024-07-01 DOI: 10.1590/2175-8239-JBN-2023-0142en

Elke Kathrin Franke, Ulrich Paul Hinkel, Christian Albert

引用次数: 0

Acute kidney injury in nonagenarians: clinical characteristics and mortality. 非老年急性肾损伤：临床特征和死亡率。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-05-24 eCollection Date: 2024-07-01 DOI: 10.1590/2175-8239-JBN-2023-0088en

Rafael Peixoto Lima Dias, Daniella Bezerra Duarte, Danilo de Castro Bulhões Mascarenhas Barbosa, Rodrigo Peixoto Campos

{"title":"Acute kidney injury in nonagenarians: clinical characteristics and mortality.","authors":"Rafael Peixoto Lima Dias, Daniella Bezerra Duarte, Danilo de Castro Bulhões Mascarenhas Barbosa, Rodrigo Peixoto Campos","doi":"10.1590/2175-8239-JBN-2023-0088en","DOIUrl":"10.1590/2175-8239-JBN-2023-0088en","url":null,"abstract":"Introduction: Nonagenarians constitute a rising percentage of inpatients, with acute kidney injury (AKI) being frequent in this population. Thus, it is important to analyze the clinical characteristics of this demographic and their impact on mortality.Methods: Retrospective study of nonagenarian patients with AKI at a tertiary hospital between 2013 and 2022. Only the latest hospital admission was considered, and patients with incomplete data were excluded. A logistic regression analysis was conducted to define risk factors for mortality. A p-value < 0.05 was considered statistically significant.Results: A total of 150 patients were included, with a median age of 93.0 years (91.2-95.0), and males accounting for 42.7% of the sample. Sepsis was the most common cause of AKI (53.3%), followed by dehydration/hypovolemia (17.7%), and heart failure (17.7%). ICU admission occurred in 39.3% of patients, mechanical ventilation in 14.7%, vasopressors use in 22.7% and renal replacement therapy (RRT) in 6.7%. Death occurred in 56.7% of patients. Dehydration/hypovolemia as an etiology of AKI was associated with a lower risk of mortality (OR 0.18; 95% CI 0.04-0.77, p = 0.020). KDIGO stage 3 (OR 3.15; 95% CI 1.17-8.47, p = 0.023), ICU admission (OR 12.27; 95% CI 3.03-49.74, p < 0.001), and oliguria (OR 5.77; 95% CI 1.98-16.85, p = 0.001) were associated with mortality.Conclusion: AKI nonagenarians had a high mortality rate, with AKI KDIGO stage 3, oliguria, and ICU admission being associated with death.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230088"},"PeriodicalIF":1.3,"publicationDate":"2024-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11197940/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141092705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute kidney injury: the experience of a tertiary center of Pediatric Nephrology. 急性肾损伤：儿科肾病学三级中心的经验。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2024-0012en

Carolina Figueiredo, Ana Margarida Rocha, Liane Correia-Costa, Maria do Sameiro Faria, Teresa Costa, Conceição Mota

{"title":"Acute kidney injury: the experience of a tertiary center of Pediatric Nephrology.","authors":"Carolina Figueiredo, Ana Margarida Rocha, Liane Correia-Costa, Maria do Sameiro Faria, Teresa Costa, Conceição Mota","doi":"10.1590/2175-8239-JBN-2024-0012en","DOIUrl":"10.1590/2175-8239-JBN-2024-0012en","url":null,"abstract":"Introduction: Acute kidney injury (AKI) is an abrupt deterioration of kidney function. The incidence of pediatric AKI is increasing worldwide, both in critically and non-critically ill settings. We aimed to characterize the presentation, etiology, evolution, and outcome of AKI in pediatric patients admitted to a tertiary care center.Methods: We performed a retrospective observational single-center study of patients aged 29 days to 17 years and 365 days admitted to our Pediatric Nephrology Unit from January 2012 to December 2021, with the diagnosis of AKI. AKI severity was categorized according to Kidney Disease Improving Global Outcomes (KDIGO) criteria. The outcomes considered were death or sequelae (proteinuria, hypertension, or changes in renal function at 3 to 6 months follow-up assessments).Results: Forty-six patients with a median age of 13.0 (3.5-15.5) years were included. About half of the patients (n = 24, 52.2%) had an identifiable risk factor for the development of AKI. Thirteen patients (28.3%) were anuric, and all of those were categorized as AKI KDIGO stage 3 (p < 0.001). Almost one quarter (n = 10, 21.7%) of patients required renal replacement therapy. Approximately 60% of patients (n = 26) had at least one sequelae, with proteinuria being the most common (n = 15, 38.5%; median (P25-75) urinary protein-to-creatinine ratio 0.30 (0.27-0.44) mg/mg), followed by reduced glomerular filtration rate (GFR) (n = 11, 27.5%; median (P25-75) GFR 75 (62-83) mL/min/1.73 m2).Conclusions: Pediatric AKI is associated with substantial morbidity, with potential for proteinuria development and renal function impairment and a relevant impact on long-term prognosis.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20240012"},"PeriodicalIF":1.3,"publicationDate":"2024-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11299983/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140945076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bone aluminum accumulation in the current era. 当今时代的骨铝积累。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-04-29 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2024-0023en

Rodrigo Bueno de Oliveira, Aluízio Barbosa Carvalho, Vanda Jorgetti

引用次数: 0

Progression of valvular heart disease in dialysis patients: how to stop it? 透析患者瓣膜性心脏病的进展：如何阻止？

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-04-08 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2024-E005en

Eduardo Leal Adam

引用次数: 0

Analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as inflammatory biomarkers in chronic kidney disease: impact of parathyroidectomy. 分析作为慢性肾脏病炎症生物标志物的中性粒细胞对淋巴细胞比率和血小板对淋巴细胞比率：甲状旁腺切除术的影响。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-04-08 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2023-0175en

Andre Kakinoki Teng, Eduardo Jorge Duque, Shirley Ferraz Crispilho, Wagner Domingues, Vanda Jorgetti, Luciene M Dos Reis, Rosilene M Elias, Rosa Maria Affonso Moysés

{"title":"Analysis of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios as inflammatory biomarkers in chronic kidney disease: impact of parathyroidectomy.","authors":"Andre Kakinoki Teng, Eduardo Jorge Duque, Shirley Ferraz Crispilho, Wagner Domingues, Vanda Jorgetti, Luciene M Dos Reis, Rosilene M Elias, Rosa Maria Affonso Moysés","doi":"10.1590/2175-8239-JBN-2023-0175en","DOIUrl":"10.1590/2175-8239-JBN-2023-0175en","url":null,"abstract":"Introduction: Secondary hyperparathyroidism (SHPT) is one of the causes for inflammation in CKD. We assessed the impact of parathyroidectomy (PTX) on neutrophil-to-lymphocyte (N/L) and platelet-to-lymphocyte (P/L) ratios in SHPT patients.Methods: A total of 118 patients [hemodialysis (HD, n = 81), and transplant recipients (TX, n = 37)] undergoing PTX between 2015 and 2021 were analyzed.Results: There was a significant reduction in calcium and PTH levels in both groups, in addition to an increase in vitamin D. In the HD group, PTX did not alter N/L and P/L ratios. In the TX group, there was a reduction in N/L and P/L ratios followed by a significant increase in total lymphocyte count.Conclusion: N/L and P/L ratios are not reliable biomarkers of inflammation in SHPT patients undergoing PTX. Uremia, which induces a state of chronic inflammation in dialysis patients, and the use of immunosuppression in kidney transplant recipients are some of the confounding factors that prevent the use of this tool in clinical practice.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230175"},"PeriodicalIF":1.3,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287880/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140857292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal. 儿童经皮肾活检：葡萄牙北部一家三级医疗中心 24 年的回顾。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-04-08 eCollection Date: 2024-01-01 DOI: 10.1590/2175-8239-JBN-2023-0143en

Patrícia Sousa, Catarina Brás, Catarina Menezes, Ramon Vizcaino, Teresa Costa, Maria Sameiro Faria, Conceição Mota

{"title":"Percutaneous kidney biopsies in children: a 24-year review in a tertiary center in northern Portugal.","authors":"Patrícia Sousa, Catarina Brás, Catarina Menezes, Ramon Vizcaino, Teresa Costa, Maria Sameiro Faria, Conceição Mota","doi":"10.1590/2175-8239-JBN-2023-0143en","DOIUrl":"10.1590/2175-8239-JBN-2023-0143en","url":null,"abstract":"Introduction: Percutaneous kidney biopsy (KB) is crucial to the diagnosis and management of several renal pathologies. National data on native KB in pediatric patients are scarce. We aimed to review the demographic and clinical characteristics and histopathological patterns in children who underwent native percutaneous KB over 24 years.Methods: Retrospective observational study of patients undergoing native percutaneous KB in a pediatric nephrology unit between 1998 and 2021, comparing 3 periods: period 1 (1998-2005), period 2 (2006-2013), and period 3 (2014-2021).Results: We found that 228 KB were performed, 78 (34.2%) in period 1, 91 (39.9%) in period 2, and 59 (25.9%) in period 3. The median age at KB was 11 (7-14) years. The main indications for KB were nephrotic syndrome (NS) (42.9%), hematuria and/or non-nephrotic proteinuria (35.5%), and acute kidney injury (13.2%). Primary glomerulopathies were more frequent (67.1%), particularly minimal change disease (MCD) (25.4%), IgA nephropathy (12.7%), and mesangioproliferative glomerulonephritis (GN) (8.8%). Of the secondary glomerulopathies, lupus nephritis (LN) was the most prevalent (11.8%). In group 1, hematuria and/or non-nephrotic proteinuria were the main reasons for KB, as opposed to NS in groups 2 and 3 (p < 0.01). LN showed an increasing trend (period 1-3: 2.6%-5.3%) and focal segmental glomerular sclerosis (FSGS) showed a slight decreasing trend (period 1-3: 3.1%-1.8%), without statistical significance.Conclusions: The main indication for KB was NS, which increased over time, justifying the finding of MCD as main histological diagnosis. LN showed an increase in incidence over time, while FSGS cases did not increase.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230143"},"PeriodicalIF":1.3,"publicationDate":"2024-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287898/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869999","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0