Association between malnutrition-inflammation score (MIS) and quality of life in elderly hemodyalisis patients.

IF 1.3 Q3 UROLOGY & NEPHROLOGY
Kelly Cristiane Rocha Lemos, Anália Nusya de Medeiros Garcia, Thais Oliveira Claizoni Dos Santos, Nathalia Fidelis Lins Vieira, Ana Célia Oliveira Dos Santos
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Abstract

Introduction: The malnutrition-inflammation process is one of the main causes of morbidity and mortality in patients with chronic kidney disease (CKD), influencing quality of life. The aim of this study was to identify the inflammatory and nutritional status of elderly hemodialysis (HD) and its association with quality of life.

Methods: This study was carried out in health services in three different cities. The Malnutrition-Inflammation Score (MIS) was used to assess the inflammatory and nutritional status, with anthropometric measurements, protein status, lean mass and function. The quality of life was assessed using KDQOL-SFTM. Data were analyzed using multivariate analysis and the Poisson model to evaluate the factors that increased the risk of developing malnutrition and inflammation.

Results: The MIS identified a 52.2% prevalence of malnutrition and inflammation in the population. In univariate analysis, most KDQOL-SFTM domains presented higher scores for nourished elderly. Anthropometric measures associated with muscle mass and functionality were lower in the malnourished elderly. Multivariate modeling revealed a higher nutritional risk of 50.6% for women and older age, since with each additional year of life the risk of malnutrition increased by 2.4% and by 0.4% with each additional month on HD. Greater arm muscle circumference (AMC) and higher serum albumin were factors for reducing malnutrition by 4.6% and 34.7%, respectively.

Conclusion: Higher serum albumin and preserved AMC have been shown to be good indicators of better nutritional status. Higher MIS was associated with poorer quality of life, older age, lower income and education, longer time on dialysis, and presence of comorbidities.

老年血液病患者营养不良-炎症评分(MIS)与生活质量之间的关系。
简介营养不良-炎症过程是慢性肾脏病(CKD)患者发病和死亡的主要原因之一,影响着患者的生活质量。本研究旨在确定血液透析(HD)老年人的炎症和营养状况及其与生活质量的关系:本研究在三个不同城市的医疗服务机构进行。采用营养不良-炎症评分(MIS)评估炎症和营养状况,同时测量人体测量指标、蛋白质状况、瘦体重和功能。生活质量采用 KDQOL-SFTM 进行评估。采用多变量分析和泊松模型对数据进行分析,以评估增加营养不良和炎症风险的因素:营养不良和炎症的发病率为 52.2%。在单变量分析中,营养不良的老年人在大多数 KDQOL-SFTM 领域的得分较高。与肌肉质量和功能相关的人体测量指标在营养不良的老年人中较低。多变量模型显示,女性和年龄较大者的营养风险要高出 50.6%,因为每多活一年,营养不良的风险就会增加 2.4%,每多服用一个月的 HD,营养不良的风险就会增加 0.4%。更大的臂围(AMC)和更高的血清白蛋白是降低营养不良的因素,分别降低了 4.6% 和 34.7%:结论:较高的血清白蛋白和保留的AMC已被证明是改善营养状况的良好指标。较高的 MIS 与生活质量较差、年龄较大、收入和教育程度较低、透析时间较长以及存在合并症有关。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.20
自引率
16.70%
发文量
208
审稿时长
16 weeks
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