Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia最新文献_第8页

An image of a giant brown tumor due to severe secondary hyperparathyroidism. 严重的继发性甲状旁腺功能亢进症导致的巨大褐色肿瘤的图像。

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Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2024-0083en

Ana Carolina de Lima, Ana Claudia Siqueira Marques, Rodrigo Bueno de Oliveira

引用次数: 0

Hospital do Rim: 25 years as the global leader in kidney transplants. Hospital do Rim：25 年来在全球肾移植领域一直处于领先地位。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2024-0076en

Maria Lúcia Vaz, Lúcio Requião-Moura, José Medina Pestana

引用次数: 0

Transitioning to peritoneal dialysis: it does not matter where you come from. 向腹膜透析过渡：来自哪里并不重要。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2023-0139en

Diogo Francisco, Andreia Carnevale, Gonçalo Ávila, Ana Rita Calça, Patrícia Matias, Patrícia Branco

{"title":"Transitioning to peritoneal dialysis: it does not matter where you come from.","authors":"Diogo Francisco, Andreia Carnevale, Gonçalo Ávila, Ana Rita Calça, Patrícia Matias, Patrícia Branco","doi":"10.1590/2175-8239-JBN-2023-0139en","DOIUrl":"10.1590/2175-8239-JBN-2023-0139en","url":null,"abstract":"Introduction: Patients with end-stage renal disease (ESRD) frequently change renal replacement (RRT) therapy modality due to medical or social reasons. We aimed to evaluate the outcomes of patients under peritoneal dialysis (PD) according to the preceding RRT modality.Methods: We conducted a retrospective observational single-center study in prevalent PD patients from January 1, 2010, to December 31, 2017, who were followed for 60 months or until they dropped out of PD. Patients were divided into three groups according to the preceding RRT: prior hemodialysis (HD), failed kidney transplant (KT), and PD-first.Results: Among 152 patients, 115 were PD-first, 22 transitioned from HD, and 15 from a failing KT. There was a tendency for ultrafiltration failure to occur more in patients transitioning from HD (27.3% vs. 9.6% vs. 6.7%, p = 0.07). Residual renal function was better preserved in the group with no prior RRT (p < 0.001). A tendency towards a higher annual rate of peritonitis was observed in the prior KT group (0.70 peritonitis/year per patient vs. 0.10 vs. 0.21, p = 0.065). Thirteen patients (8.6%) had a major cardiovascular event, 5 of those had been transferred from a failing KT (p = 0.004). There were no differences between PD-first, prior KT, and prior HD in terms of death and technique survival (p = 0.195 and p = 0.917, respectively) and PD efficacy was adequate in all groups.Conclusions: PD is a suitable option for ESRD patients regardless of the previous RRT and should be offered to patients according to their clinical and social status and preferences.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230139"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287956/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140891174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hashimoto's thyroiditis masquerading as acute tubular injury and rhabdomyolysis. 伪装成急性肾小管损伤和横纹肌溶解症的桥本氏甲状腺炎。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2024-0022en

Gerry George Mathew, Varadharajan Jayaprakash

引用次数: 0

Nephrology and experimental medicine in vivo, in vitro, and in silico. 肾脏病学和实验医学的体内、体外和硅学研究。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2024-0004en

Mauricio Younes-Ibrahim

引用次数: 0

Dietitians' practices in dialysis units in Brazil: nutritional assessment and intervention. 巴西透析室营养师的实践：营养评估和干预。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2023-0092en

Fabiana Baggio Nerbass, Aline de Araujo Antunes, Lilian Cuppari

{"title":"Dietitians' practices in dialysis units in Brazil: nutritional assessment and intervention.","authors":"Fabiana Baggio Nerbass, Aline de Araujo Antunes, Lilian Cuppari","doi":"10.1590/2175-8239-JBN-2023-0092en","DOIUrl":"10.1590/2175-8239-JBN-2023-0092en","url":null,"abstract":"Introduction: The importance of dietitians in dialysis units is indisputable and mandatory in Brazil, but little is known about the practices adopted by these professionals.Objective: To know practices adopted in routine nutritional care, focusing on nutritional assessment tools and treatment strategies for people at risk or diagnosed with malnutrition.Methodology: Electronic questionnaire disseminated on social media and messaging applications. It included questions that covered dietitians' demographic and occupational profile characteristics and of the dialysis unit, use and frequency of nutritional assessment tools, nutritional intervention strategies in cases of risk or diagnosis of malnutrition, prescription and access to oral supplements.Results: Twenty four percent of the Brazilian dialysis units (n = 207) responded electronically. The most used nutritional assessment tools with or without a pre-established frequency were dietary surveys (96%) and Subjective Global Assessment (83%). The strategies in cases of risk or presence of malnutrition used most frequently (almost always/always) were instructions to increase energy and protein intake from foods (97%), and increasing the frequency of visits (88%). The frequency of prescribing commercial supplements with standard and specialized formulas was quite similar. The availability of dietary supplements by the public healthcare system to patients varied between regions.Conclusion: Most dietitians use various nutritional assessment tools and intervention strategies in cases of risk or malnutrition; however, the frequency of use of such tools and strategies varied substantially.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230092"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11296690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140158163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Obituary of Dr. Julio Toporovski. 胡利奥-托波洛夫斯基博士的讣告。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2024-IM003en

Maria Helena Vaisbich, Olberes Vitor Braga de Andrade, Maria Goretti Moreira Guimarães Penido

引用次数: 0

The role of podocyte injury in the pathogenesis of Fabry disease nephropathy. 荚膜损伤在法布里病肾病发病机制中的作用。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2024-0035en

José Tiburcio do Monte Neto, Gianna Mastroianni Kirsztajn

{"title":"The role of podocyte injury in the pathogenesis of Fabry disease nephropathy.","authors":"José Tiburcio do Monte Neto, Gianna Mastroianni Kirsztajn","doi":"10.1590/2175-8239-JBN-2024-0035en","DOIUrl":"10.1590/2175-8239-JBN-2024-0035en","url":null,"abstract":"Renal involvement is one of the most severe morbidities of Fabry disease (FD), a multisystemic lysosomal storage disease with an X-linked inheritance pattern. It results from pathogenic variants in the GLA gene (Xq22.2), which encodes the production of alpha-galactosidase A (α-Gal), responsible for glycosphingolipid metabolism. Insufficient activity of this lysosomal enzyme generates deposits of unprocessed intermediate substrates, especially globotriaosylceramide (Gb3) and derivatives, triggering cellular injury and subsequently, multiple organ dysfunction, including chronic nephropathy. Kidney injury in FD is classically attributed to Gb3 deposits in renal cells, with podocytes being the main target of the pathological process, in which structural and functional alterations are established early and severely. This configures a typical hereditary metabolic podocytopathy, whose clinical manifestations are proteinuria and progressive renal failure. Although late clinical outcomes and morphological changes are well established in this nephropathy, the molecular mechanisms that trigger and accelerate podocyte injury have not yet been fully elucidated. Podocytes are highly specialized and differentiated cells that cover the outer surface of glomerular capillaries, playing a crucial role in preserving the structure and function of the glomerular filtration barrier. They are frequent targets of injury in many nephropathies. Furthermore, dysfunction and depletion of glomerular podocytes are essential events implicated in the pathogenesis of chronic kidney disease progression. We will review the biology of podocytes and their crucial role in regulating the glomerular filtration barrier, analyzing the main pathogenic pathways involved in podocyte injury, especially related to FD nephropathy.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20240035"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287863/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Common arboviruses and the kidney: a review. 常见虫媒病毒与肾脏：综述。

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2023-0168en

Gabriel Rotsen Fortes Aguiar, Geraldo Bezerra da Silva Júnior, Janaína de Almeida Mota Ramalho, Nattachai Srisawat, Elizabeth de Francesco Daher

{"title":"Common arboviruses and the kidney: a review.","authors":"Gabriel Rotsen Fortes Aguiar, Geraldo Bezerra da Silva Júnior, Janaína de Almeida Mota Ramalho, Nattachai Srisawat, Elizabeth de Francesco Daher","doi":"10.1590/2175-8239-JBN-2023-0168en","DOIUrl":"10.1590/2175-8239-JBN-2023-0168en","url":null,"abstract":"Arboviruses are endemic in several countries and represent a worrying public health problem. The most important of these diseases is dengue fever, whose numbers continue to rise and have reached millions of annual cases in Brazil since the last decade. Other arboviruses of public health concern are chikungunya and Zika, both of which have caused recent epidemics, and yellow fever, which has also caused epidemic outbreaks in our country. Like most infectious diseases, arboviruses have the potential to affect the kidneys through several mechanisms. These include the direct action of the viruses, systemic inflammation, hemorrhagic phenomena and other complications, in addition to the toxicity of the drugs used in treatment. In this review article, the epidemiological aspects of the main arboviruses in Brazil and other countries where these diseases are endemic, clinical aspects and the main laboratory changes found, including changes in renal function, are addressed. It also describes how arboviruses behave in kidney transplant patients. The pathophysiological mechanisms of kidney injury associated with arboviruses are described and finally the recommended treatment for each disease and recommendations for kidney support in this context are given.","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"46 3","pages":"e20230168"},"PeriodicalIF":1.3,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11287847/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141792557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sodium-glucose cotranspor ter 2 (SGLT2) inhibitors in nephrolithiasis: should we "gliflozin" patients with kidney stone disease? 钠-葡萄糖共转移酶 2 (SGLT2) 抑制剂在肾结石中的应用：我们是否应该为肾结石患者 "格列氯嗪"？

IF 1.3

Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia Pub Date : 2024-07-01 DOI: 10.1590/2175-8239-JBN-2023-0146en

Mauricio de Carvalho, Ita Pfeferman Heilberg

引用次数: 0