{"title":"Acute kidney injury after heart transplantation: still a shadow after all these years.","authors":"Renata Mendes, José Hermógenes Rocco Suassuna","doi":"10.1590/2175-8239-JBN-2026-E006en","DOIUrl":"10.1590/2175-8239-JBN-2026-E006en","url":null,"abstract":"","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"48 1","pages":"e2026E006"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12970628/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147377546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marcus Gomes Bastos, José A Moura-Neto, Pedro Túlio Monteiro de Castro de Abreu Rocha
{"title":"NefrUS: ultrasonography in nephrology - an initiative of the Brazilian Society of Nephrology for ultrasound training in nephrology practice.","authors":"Marcus Gomes Bastos, José A Moura-Neto, Pedro Túlio Monteiro de Castro de Abreu Rocha","doi":"10.1590/2175-8239-JBN-2025-0331en","DOIUrl":"10.1590/2175-8239-JBN-2025-0331en","url":null,"abstract":"","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"48 1","pages":"e20250331"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965625/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147369473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Innovation in daily hemodialysis: high-flux vs. hemodiafiltration.","authors":"Dirceu Reis da Silva","doi":"10.1590/2175-8239-JBN-2026-E003en","DOIUrl":"10.1590/2175-8239-JBN-2026-E003en","url":null,"abstract":"","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"48 1","pages":"e2026E003"},"PeriodicalIF":1.6,"publicationDate":"2026-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12965626/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147369493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana Batista Pereira, Patrícia Oliveira Costa Eloy, Kleyton de Andrade Bastos
{"title":"Nephrologists' perceptions of competencies acquired during medical residency in Nephrology and their applicability to daily clinical practice.","authors":"Mariana Batista Pereira, Patrícia Oliveira Costa Eloy, Kleyton de Andrade Bastos","doi":"10.1590/2175-8239-JBN-2025-0024en","DOIUrl":"10.1590/2175-8239-JBN-2025-0024en","url":null,"abstract":"<p><strong>Introduction: </strong>The medical residency (MR) curriculum underwent a reformulation, and in 2021, the competency matrix for MR in nephrology was published. This study aimed to evaluate nephrologists' perceptions of the competencies acquired during residency and their relevance in clinical practice.</p><p><strong>Method: </strong>This was a cross-sectional study conducted using a self-administered electronic questionnaire, which included demographic data, information on professional practice, and an assessment of both the learning and the usefulness of the skills acquired during the MR program in nephrology. Participants responded to questions on a five-point Likert scale. Only nephrologists who had graduated from programs accredited by the Brazilian Ministry of Education were included.</p><p><strong>Results: </strong>A total of 163 nephrologists from different states in Brazil were included. Most considered the clinical skills acquired to be useful for practice, except for palliative care, in which 54% felt capable, although 93.2% considered it essential. Procedures for which usefulness exceeded self-reported competence included fundoscopy, insertion of permanent hemodialysis catheters, insertion of peritoneal dialysis catheters, and ultrasonography. Furthermore, less than 40% of participants reported feeling prepared to engage in management, clinical research, and teaching activities, despite perceiving their relevance.</p><p><strong>Conclusion: </strong>The study highlights nephrologists' perceptions of competencies acquired during MR and underscores the need for improvements in nephrology training, particulary in management, teaching, and research.</p>","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e20250024"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12604310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145523593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Guilherme Nobre Nogueira, Elizabeth De Francesco Daher
{"title":"Effects of vaping on kidney function: a systematic review on acute kidney injury and chronic kidney disease.","authors":"Guilherme Nobre Nogueira, Elizabeth De Francesco Daher","doi":"10.1590/2175-8239-JBN-2024-0216en","DOIUrl":"10.1590/2175-8239-JBN-2024-0216en","url":null,"abstract":"<p><p>The increase use of vaping, especially in the younger population, has led to increased scrutiny of its health effects, particularly on renal function. This article reviews the current literature on the association between vaping, nicotine exposure, and renal impairment, focusing on the development of acute kidney injury (AKI) and chronic kidney disease (CKD). Nicotine and other chemicals in e-liquids may induce microangiopathy, leading to vasoconstriction and reduced renal perfusion, thus contributing to AKI. Chronic exposure to nicotine also promotes an inflammatory response, increasing the risk of interstitial nephritis. Additionally, glomerular damage due to continuous use of vapers has been linked to albuminuria and progression of focal segmental glomerulosclerosis (FSGS), a condition that can lead to CKD. This article highlights the need for further research to clarify the kidney risks associated with vaping and provides information for public health policies on nicotine use.</p>","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e20240216"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517560/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286312","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on \"The association between the Kidney Donor Profile Index and one-year outcomes in Brazilian kidney transplant recipients of standard criteria donors\".","authors":"Umaima Parveen, Eisha Abid","doi":"10.1590/2175-8239-JBN-2025-0255en","DOIUrl":"10.1590/2175-8239-JBN-2025-0255en","url":null,"abstract":"","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e20250255"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12700439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145557014","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gabriel Teixeira Montezuma Sales, Natália Janoni Macedo, Edgard Torres Dos Reis Neto, Gianna Mastroianni Kirsztajn
{"title":"Current treatment of lupus nephritis: an overview of the new guidelines.","authors":"Gabriel Teixeira Montezuma Sales, Natália Janoni Macedo, Edgard Torres Dos Reis Neto, Gianna Mastroianni Kirsztajn","doi":"10.1590/2175-8239-JBN-2025-0092en","DOIUrl":"10.1590/2175-8239-JBN-2025-0092en","url":null,"abstract":"<p><strong>Introduction: </strong>Given the relevance of renal involvement in systemic lupus erythematosus (SLE) and new approaches to the disease and its treatment, this article aimed to synthesize the main updates in the diagnosis, management, and treatment of lupus nephritis (LN), based on recent publications of international reference guidelines in nephrology and rheumatology, in addition to highlighting aspects of interest from the 2024 national guidelines of the Brazilian Society of Rheumatology (SBR). The treatments for each class of lupus nephritis are described, as well as the therapeutic targets, underlining similarities and differences between the guidelines. In general, they recommend that induction (\"initial\") treatment of proliferative classes be performed with monotherapy using mycophenolate or intravenous cyclophosphamide, or with multitarget regimens, using corticosteroids, mycophenolate or cyclophosphamide, and a calcineurin inhibitor or belimumab as a third drug. A change in therapy should be considered if the expected response target is not achieved, which presents subtle differences among current consensus guidelines. Maintenance (\"subsequent\") treatment should preferably be performed with mycophenolate, azathioprine, or multi-target therapies. Emerging scientific evidence has provided treatment options that impact the management of lupus nephritis, thereby justifying the publication of new guidelines in recent months. Critically analyzing these guidelines may assist in decision-making for the individualized treatment of individuals with this disease.</p>","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e20250092"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520630/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286281","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Fractures in CKD predialysis: the role of bone biopsy, biomarkers, and FRAX®.","authors":"Aluízio Barbosa Carvalho","doi":"10.1590/21758239-JBN-2025-E016en","DOIUrl":"10.1590/21758239-JBN-2025-E016en","url":null,"abstract":"","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e2025E016"},"PeriodicalIF":1.6,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12668541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145654347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reply to letter: outdated or underrated? the case for low-protein diets in CKD.","authors":"Abdullah Bawazir, Joel M Topf, Swapnil Hiremath","doi":"10.1590/2175-8239-JBN-2025-0065rpen","DOIUrl":"10.1590/2175-8239-JBN-2025-0065rpen","url":null,"abstract":"","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e20250065rp"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12533501/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145308081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Julia Gheller Salome, Lucas Peres Moraes, Rodrigo Hagemann, Vanessa Dos Santos Silva, Fabio Cardoso Carvalho, Roberto Jorge da Silva Franco, Diana Vassallo, Luis Cuadrado Martin, Philip A Kalra, Pasqual Barretti
{"title":"Long-term mortality and predictive score performance in Brazilian atherosclerotic renovascular disease patients.","authors":"Julia Gheller Salome, Lucas Peres Moraes, Rodrigo Hagemann, Vanessa Dos Santos Silva, Fabio Cardoso Carvalho, Roberto Jorge da Silva Franco, Diana Vassallo, Luis Cuadrado Martin, Philip A Kalra, Pasqual Barretti","doi":"10.1590/2175-8239-JBN-2024-0181en","DOIUrl":"10.1590/2175-8239-JBN-2024-0181en","url":null,"abstract":"<p><strong>Introduction: </strong>Atherosclerotic renovascular disease (ARVD) can cause renal artery stenosis, hypertension, and chronic kidney disease. As revascularization procedure for ARVD is controversial, a risk score was developed to predict mortality in affected patients, which requires validation in different populations. The original risk score did not include statin use; therefore, the aim of this study was to evaluate the accuracy of the risk score in ARVD patients according to statins intake.</p><p><strong>Methods: </strong>Longitudinal retrospective study involving 136 patients with angiographic diagnosis of RAS > 60% from January 1996 to October 2008. Cox regression analysis was performed to assess all-cause mortality associations. To evaluate the discriminatory power of the risk score, ROC curves were constructed for mortality at 1, 5, and 10 years for those with and without statin use.</p><p><strong>Results: </strong>103 patients were included, 69 of whom were taking statins. After 1, 5, and 10 years, survival rates predicted by the risk score for patients using statins were, respectively, 0.87 (95% CI [0.76;0.97]), 0. 45 (95% CI [0.37;0.55]), and 0.15 (95% CI [0.09;0.22]). Actual survival rates were 0.95, 0.88, and 0.72. For the 34 patients who did not use statins, predicted survival rates were 0.84 (95% CI [0.71;0.97]), 0.43 (IC 95% [0.32;0.55]), and 0.14 (95% CI [0.05;0.22]); actual survival rates were 0.83, 0.36, and 0.29.</p><p><strong>Conclusion: </strong>Patients receiving statins had greater survival rate after 5 and 10 years when compared to calculations by the risk score. The 34 patients who did not use statins had survival rates close to the predicted survival. Therefore, the risk score should be modified to include use of statins.</p>","PeriodicalId":14724,"journal":{"name":"Jornal brasileiro de nefrologia : 'orgao oficial de Sociedades Brasileira e Latino-Americana de Nefrologia","volume":"47 4","pages":"e20240181"},"PeriodicalIF":1.3,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12517691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145286293","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}