ChemistrySelect最新文献_第6页

Facile Fabrication of Pumice-Supported Palladium Nanocatalyst for the Catalytic Reduction of Nitroaromatic Compounds 浮石负载钯纳米催化剂催化还原硝基芳香族化合物的制备

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74625

Sema Akay, Melike Çalışkan, Berkant Kayan, Talat Baran

{"title":"Facile Fabrication of Pumice-Supported Palladium Nanocatalyst for the Catalytic Reduction of Nitroaromatic Compounds","authors":"Sema Akay, Melike Çalışkan, Berkant Kayan, Talat Baran","doi":"10.1002/slct.74625","DOIUrl":"https://doi.org/10.1002/slct.74625","url":null,"abstract":"<div>\u0000 \u0000 In this study, a new palladium (Pd) nanocatalyst was prepared using pumice (PM) as an alternative support material for the heterogeneous reduction of nitroaromatic compounds (NACs). Pd nanoparticles were immobilized on the PM surface, and the designed Pd@PM nanostructure was characterized using X-ray diffraction (XRD), Field-emission scanning electron microscopy (FE-SEM), energy-dispersive X-ray spectroscopy (EDS), and transmission electron microscopy (TEM) analyses. The synthesized Pd@PM nanocatalyst was successfully applied in the catalytic reduction of NACs, such as 2-nitroaniline (2-NA), 3-nitroanisole (3-NAS), 4-nitroaniline (4-NA), 4-nitrobenzoic acid (4-NBA), and 4-nitro-o-phenylenediamine (4-NPD). Pd@PM showed good catalytic performance by efficiently supporting the reduction of NACs in short reaction times within 48–420 s. The formation of the corresponding amine products was confirmed by high-performance liquid chromatography (HPLC), with distinct retention times supporting the successful conversion of all substrates. Furthermore, the reusability of the Pd@PM nanocatalyst was investigated over five consecutive cycles, demonstrating good reusability, although a gradual decrease in catalytic performance was observed during the later cycles. The main innovation of this study is the direct use of naturally porous pumice as a simple, low-cost support for Pd nanoparticles, providing a recoverable heterogeneous platform for rapid aqueous-phase conversion of hazardous nitroaromatic pollutants into value-added amines.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014771","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Compatibility of Sealing Elastomers With Palm Biodiesel (B100): Elastomer and Fuel Property Changes After Exposure 密封弹性体与棕榈生物柴油（B100）的相容性：暴露后弹性体和燃料特性的变化

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74529

Valentina Cusba Arismendy, Erika Viviana Díaz Becerra, Helen Inciarte, Laura M. Orozco, Claudia Gómez, Luis Rios

{"title":"Compatibility of Sealing Elastomers With Palm Biodiesel (B100): Elastomer and Fuel Property Changes After Exposure","authors":"Valentina Cusba Arismendy, Erika Viviana Díaz Becerra, Helen Inciarte, Laura M. Orozco, Claudia Gómez, Luis Rios","doi":"10.1002/slct.74529","DOIUrl":"https://doi.org/10.1002/slct.74529","url":null,"abstract":"<div>\u0000 \u0000 The compatibility between biodiesel and elastomeric sealing materials is a key factor for the reliable operation of fuel storage and transportation systems. This study evaluates the interaction between B100 (pure) biodiesel and three elastomers used in sealing applications: ethylene-propylene-diene rubber (EPDM), nitrile-butadiene rubber (NBR), and fluorocarbon rubber (FKM). Immersion tests were conducted by exposing the elastomers to biodiesel at 70°C for 70 h. Changes in biodiesel properties and the elastomers were assessed. After exposure, no significant variations were detected in the fatty acid methyl ester (FAME) composition of the biodiesel. Fuel darkening, the formation of insoluble species at low temperatures, and the increase in induction time (oxidative stability test) were observed after elastomer exposure, suggesting the migration of elastomer-derived additives into biodiesel. EPDM showed the largest mass and volume increases, while NBR displayed intermediate behavior. FKM showed minimal changes and higher resistance to biodiesel-induced swelling. Mechanical characterization further indicated plasticization effects in EPDM and NBR. EPDM also exhibited the greatest reductions in hardness, tensile strength, and elongation at break. Compatibility trend under the studied conditions followed the order FKM >> NBR ≥ EPDM. Complementary field evaluations under real operating conditions confirmed satisfactory performance of NBR O-rings for 5 months.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Microfluidic Electrochemical Immunosensor for Point-of-Care Testing of Cystatin C in Human Serum 用于人血清胱抑素C即时检测的微流控电化学免疫传感器

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74623

Haomiao He, Xiuqiang Dai, Jing Wei, Yongzhong Wang, Xiaofeng Jin

{"title":"A Microfluidic Electrochemical Immunosensor for Point-of-Care Testing of Cystatin C in Human Serum","authors":"Haomiao He, Xiuqiang Dai, Jing Wei, Yongzhong Wang, Xiaofeng Jin","doi":"10.1002/slct.74623","DOIUrl":"https://doi.org/10.1002/slct.74623","url":null,"abstract":"<div>\u0000 \u0000 Chronic kidney disease (CKD) is a progressive disorder characterized by structural and functional alterations in the kidneys arising from various etiologies. Cystatin C (Cys C) is regarded as a superior endogenous biomarker because it is less affected by confounding factors such as age and gender. In this work, an electrochemical immunosensor was developed for Cys C detection by electropolymerizing o-phenylenediamine (OPD) on the electrode surface via cyclic voltammetry (CV) to form poly(o-phenylenediamine) (PoPD). The PoPD layer not only accelerated electron-transfer kinetics but also provided a favorable matrix for antibody immobilization. The immunosensor achieved a limit of detection (LOD) of 186.88 ng mL−1 and a linear range of 500–6000 ng mL−1, while exhibiting satisfactory reproducibility, specificity, and operational stability. Spike recovery studies and direct analysis of human serum samples verified the practical performance of the proposed sensor. A low-cost, portable microfluidic electrochemical device was developed for serum Cys C quantification. The integration of electrochemical sensing with the microfluidic platform offers low sample consumption, simplified operation, fast detection, and promising potential for POCT.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile Synthesis of Cu(OH)2 Rods Supported on Activated Carbon as Efficient Catalyst for Nitrophenol Reduction 活性炭负载Cu(OH)2棒催化硝基苯酚还原的简易合成

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74609

Tianyu Xu, Jian Yang, Yicheng Wang, Lin Zhou

{"title":"Facile Synthesis of Cu(OH)2 Rods Supported on Activated Carbon as Efficient Catalyst for Nitrophenol Reduction","authors":"Tianyu Xu, Jian Yang, Yicheng Wang, Lin Zhou","doi":"10.1002/slct.74609","DOIUrl":"https://doi.org/10.1002/slct.74609","url":null,"abstract":"<div>\u0000 \u0000 Aromatic amines constitute pivotal structural motifs in fine chemicals and environmental remediation, necessitating efficient catalysts for nitroarene reduction. Inspired by commercial Pd/C, we devised a facile one-step protocol to in-situ grow needle-like Cu(OH)2 nanocrystals on activated carbon, affording Cu(OH)2@AC composites. Systematic XRD, XPS, and TEM characterizations elucidated their phase composition and microstructure. In aqueous NaBH4-mediated reductions, the optimal Cu(OH)2@AC-3 delivered activity rivaling commercial Pd/C while outperforming numerous reported non-noble-metal catalysts for the reduction of p-nitrophenol (particularly 4-nitrophenol), and showed the potential to be extended to a broader scope of nitroarene reductions. The catalyst retained robust performance over ten consecutive cycles with negligible copper leaching (0.07%), evidencing strong interfacial metal-support interaction. Kinetic analysis confirmed that the reduction followed pseudo-first-order kinetics, and the apparent rate constant k was determined accordingly. The catalyst integrates facile preparation, earth-abundant raw materials, and low cost, coupled with excellent scalability for large-scale production, holding substantial promise for applications in wastewater remediation and fine chemical synthesis.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of Dielectric Constant and Electrical Conductivity of Poly(MA-co-MMA)/Ce(NO3)3 Composites by Response Surface Methodology for Advanced Dielectric Applications 基于响应面法的Poly(MA-co-MMA)/Ce(NO3)3复合材料介电常数和电导率研究

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74606

Gülben Torğut, Rabia İncesu

{"title":"Investigation of Dielectric Constant and Electrical Conductivity of Poly(MA-co-MMA)/Ce(NO3)3 Composites by Response Surface Methodology for Advanced Dielectric Applications","authors":"Gülben Torğut, Rabia İncesu","doi":"10.1002/slct.74606","DOIUrl":"https://doi.org/10.1002/slct.74606","url":null,"abstract":"<div>\u0000 \u0000 In this study, poly(maleic anhydride-co-methyl methacrylate) [poly(MA-co-MMA)] copolymer and their Ce(NO3)3-filled composites were synthesized and systematically investigated. The copolymer was prepared via free radical polymerization using azobisisobutyronitrile (AIBN) as the initiator in 1,4-dioxane medium. Poly(MA-co-MMA)/Ce(NO3)3 composites were fabricated through a solution mixing technique in accordance with the response surface methodology (RSM) design. Fourier transform infrared spectroscopy (FTIR) results indicated that no significant chemical interaction occurred between the polymer molecule and Ce(NO3)3 particles. Scanning electron microscopy (SEM) images revealed a relatively uniform dispersion of Ce(NO3)3 particles within the polymer, resulting in a rougher surface with increasing filler content and that aggregation occurs at 20 wt%. The presence of Ce(NO3)3 particles in the polymer was confirmed by x-ray diffraction (XRD) analysis. The effects of frequency, applied voltage, and Ce(NO3)3 content on dielectric constant (ε) and electrical conductivity (σ) were optimized using RSM, and the significance of these parameters was evaluated by analysis of variance (ANOVA). An increase in Ce(NO3)3 content significantly enhanced the electrical conductivity, while the applied voltage exhibited no statistically significant effect on dielectric properties. ANOVA results identified Ce(NO3)3 content as the most influential parameter in the developed model.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014770","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anti-Acne and Antidiabetic Profiling of Murraya koenigii (L.) Spreng. Fruits 锦鲤抗痤疮和抗糖尿病研究Spreng。水果

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.202505139

Kummamuru Laxmi Haritha, Ritu Sharma, Rajinder K. Gupta

{"title":"Anti-Acne and Antidiabetic Profiling of Murraya koenigii (L.) Spreng. Fruits","authors":"Kummamuru Laxmi Haritha, Ritu Sharma, Rajinder K. Gupta","doi":"10.1002/slct.202505139","DOIUrl":"https://doi.org/10.1002/slct.202505139","url":null,"abstract":"<div>\u0000 \u0000 The current study investigates the bioactive compounds, anti-acne, and antidiabetic profiling of Murraya koenigii (L.) Spreng. (M. koenigii) fruits. The bioactive profiling evaluated using GC–MS and UHPLC-QTOF-MS analysis identified 64 volatile compounds, and 74 major secondary metabolites. The α-amylase inhibitory assay showed IC50 value of 0.97 µL/mL for oval fruit, and 9.67 µL/mL for round fruit. The α-glucosidase inhibitory assay showed an IC50 value of 1.62 µL/mL for oval fruit, and 3.90 µL/mL. The DPP-IV inhibitor activity was 0.74% for oval and 1.37% for round fruits. Insulin secretion assay showed 265.09 U/mL cell lysate for oval fruits, and 272.55 U/mL cell lysate for round fruits, as compared to control cells without treatment (156.55 U/mL cell lysate). Glucose uptake assay on the L6-cell line for oval fruits extract was 196.15 µg/mL compared to control (506.48 µg/mL) and 206 µg/mL for round fruit extract. Cytotoxicity assay showed IC50 values of 392.2 ± 0.16 µg/mL and 412.2 ± 0.13 µg/mL for oval and round fruit extracts, respectively. Both types of fruit extract did not show any toxic effects. According to the findings, M. koenigii fruits may be a valuable natural source of bioactive compounds that have anti-acne and antidiabetes properties.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anthracenyl Benzimidazole: A Smart Optical Probe for Determination of Bilirubin at Nanomolar Level 蒽基苯并咪唑：用于纳米水平胆红素测定的智能光学探针

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74594

Sukriti Mukherjee, Sutapa Changdar, Somnath Khanra, Sisir Lohar, Debasis Das

引用次数: 0

Homogeneous Ethanol CuCl2/TMEDA/TEMPO System Mimicking Laccase/TEMPO for the Catalytic Aerobic Oxidation of Primary Furyl, Allyl and Benzyl Alcohols 模拟漆酶/TEMPO的均相乙醇CuCl2/TMEDA/TEMPO体系对伯呋喃醇、烯丙基醇和苯甲醇的催化好氧氧化

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74620

Emmanuel Dias da Silva, João Luiz Petrarca de Albuquerque, Alcindo Aparecido dos Santos, Lorena de Fontgaland Costa, José Augusto Ferreira Perez Villar, Jefferson Luiz Princival

引用次数: 0

Pyridin-2-ylsulfinylfluoroacetate Reagent for the Stereoselective Synthesis of Z‑Monofluoroalkenes 吡啶-2-酰基亚砜基氟乙酸酯立体选择性合成Z -单氟烯烃试剂

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74572

Satoshi Osada, Hiroto Shikasho, Kazuki Nakamoto, Takayuki Kimiya, Hiroaki Kodama, Kazuyasu Sakaguchi

引用次数: 0

Template-Derived Engineering of Peptide Inhibitors Targeting HSP90–CDC37 Interface: A Theoretical Framework for Cancer Therapeutics 靶向HSP90-CDC37界面的肽抑制剂的模板衍生工程：癌症治疗的理论框架

IF 2.3 4区化学

ChemistrySelect Pub Date : 2026-09-23 DOI: 10.1002/slct.74551

Sarath Perumal, Ramanathan Karuppasamy

{"title":"Template-Derived Engineering of Peptide Inhibitors Targeting HSP90–CDC37 Interface: A Theoretical Framework for Cancer Therapeutics","authors":"Sarath Perumal, Ramanathan Karuppasamy","doi":"10.1002/slct.74551","DOIUrl":"https://doi.org/10.1002/slct.74551","url":null,"abstract":"<div>\u0000 \u0000 The HSP90–CDC37 complex plays a key role in stabilizing multiple oncogenic client proteins, thereby sustaining cancer cell survival. However, targeting these dynamic interfaces remains challenging due to the large, shallow binding surfaces, which limit the effectiveness of conventional small-molecule inhibitors. Peptide-based therapeutics offer a promising alternative owing to their ability to mimic native motifs. Two continuous interfacial segments from CDC37 were extracted to construct template peptides, which were used to generate peptide libraries. A multi-level hierarchical screening strategy was applied to evaluate 4050 and 843,750 sequences derived from Template-1 and Template-2, respectively, thereby prioritizing top candidates based on binding profiles and physicochemical suitability. The shortlisted peptides were further validated using the Boltz-2 deep learning framework to enhance confidence in the predicted peptide structures and protein–peptide complexes. Binding free-energy and molecular dynamics simulation analyses were subsequently performed to assess their interaction with HSP90. The lead peptide was then benchmarked against positive and negative controls to provide a relative assessment of its binding performance. Collectively, these findings identify Pep14 derived from Template-2 as a lead peptide candidate for disrupting the HSP90–CDC37 interaction. However, further experimental validation is required to confirm its therapeutic potential in cancer treatment.\u0000 </div>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"11 37","pages":""},"PeriodicalIF":2.3,"publicationDate":"2026-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149014661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0