ChemistrySelect最新文献_第6页

Enhancing Dry Reforming of Methane with Calcium-Substituted LaNiO₃ Perovskite Catalysts for Syngas Production and Carbon Resistance 钙取代LaNiO₃钙钛矿催化剂增强甲烷干重整制合成气及抗碳性能

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202403401

Chao-Wei Huang, Po-Chou Chen, Yu-Tang Lin, To-Yu Wang, Duo-Syuan Lin, Ying-Shuo Cheng, Dong-En Wu, Kanit Manatura, Wei-Yu Chen, Kun-Yi Andrew Lin, Andrew C. Chien

{"title":"Enhancing Dry Reforming of Methane with Calcium-Substituted LaNiO₃ Perovskite Catalysts for Syngas Production and Carbon Resistance","authors":"Chao-Wei Huang, Po-Chou Chen, Yu-Tang Lin, To-Yu Wang, Duo-Syuan Lin, Ying-Shuo Cheng, Dong-En Wu, Kanit Manatura, Wei-Yu Chen, Kun-Yi Andrew Lin, Andrew C. Chien","doi":"10.1002/slct.202403401","DOIUrl":"https://doi.org/10.1002/slct.202403401","url":null,"abstract":"Perovskite La1-xCaxNiO3 catalysts doped with varying molar ratios of Ca (x = 0.1, 0.2, 0.3) were investigated to enhance the efficiency of dry reforming of methane (DRM). The experiments were conducted under operational conditions with a CO2/CH4 feed ratio 1:1 at atmospheric pressure and various reaction temperatures ranging from 550 to 800 °C. At 800 °C, the LaNiO3 catalyst achieved a CH4 conversion rate of 63.3% and a syngas H2/CO ratio of 0.56. In contrast, the La1-xCaxNiO3 catalyst, with partial substitution of Ca where x = 0.3, demonstrated markedly enhanced CH4 conversion rates of 98.05%, coupled with syngas production showcasing an H2/CO ratio of 0.98. This underscores the superior catalytic activity of the Ca-substituted perovskite LaNiO3 catalysts, which not only achieved a comparable CH4 conversion rate at 800 °C but also allowed for the adjustment of the syngas H2/CO ratio closer to 1.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Unveiling the Synthesis, Characterization, and Multifunctional Applications of Ca₅(PO₄)₃F@Ca₅P₈ Nanocomposites From Phosphate Waste for Antioxidant Activity and Evans Bleu Decomposition 揭示Ca₅（PO₄）₃F@Ca₅P₈磷酸盐废料纳米复合材料的合成、表征和多功能应用，用于抗氧化活性和埃文斯蓝分解

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202406193

Amina Tabet, Abderrhmane Bouafia, Khansaa Al-Essa, Ibtissam Laib, Salah Eddine Laouini, Fahad Alharthi, Abdullah Al Souwaileh, Mokni-Tlili Sonia, Tomasz Trzepieciński

{"title":"Unveiling the Synthesis, Characterization, and Multifunctional Applications of Ca₅(PO₄)₃F@Ca₅P₈ Nanocomposites From Phosphate Waste for Antioxidant Activity and Evans Bleu Decomposition","authors":"Amina Tabet, Abderrhmane Bouafia, Khansaa Al-Essa, Ibtissam Laib, Salah Eddine Laouini, Fahad Alharthi, Abdullah Al Souwaileh, Mokni-Tlili Sonia, Tomasz Trzepieciński","doi":"10.1002/slct.202406193","DOIUrl":"https://doi.org/10.1002/slct.202406193","url":null,"abstract":"This study explores the innovative synthesis and versatile applications of Ca₅(PO₄)₃F@Ca₅P₈ nanocomposites (NCs), crafted from phosphate waste sourced from Djebel Onk, Algeria, advancing sustainable material use and environmental remediation. FTIR analysis unveiled distinct functional groups, including C─H, P─H, P─O, and F─Ca, underscoring the material's chemical richness, while XRD revealed a crystalline architecture blending hexagonal (Ca₅(PO₄)₃F) and monoclinic (Ca₅P₈) phases, with a precise crystallite size of 22.45 ± 1.18 nm. SEM and EDS showcased uniform spherical particles averaging 24 nm, brimming with Ca, P, O, and F elements. Optical properties dazzled with peak absorption at 391 nm, direct and indirect bandgaps of 1.62 and 2.98 eV, and an Urbach energy of 0.435 eV, signaling exceptional UV–visible absorption capabilities. Beyond its structural elegance, the nanocomposite exhibited remarkable antioxidant prowess, neutralizing nearly 100% of hydrogen peroxide, and delivered striking photocatalytic performance, degrading 99.2% of Evans Blue dye in just 140 min (rate constant 0.01334 min−1). Antibacterial assays further highlighted its potency, effectively combating S. aureus, C. albicans, and other microbes. These compelling results position Ca₅(PO₄)₃F@Ca₅P₈ NCs as a multifunctional powerhouse for water treatment, photocatalysis, and antibacterial applications, paving the way for sustainable technological breakthroughs.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of Quinazoline-1,3,4-Oxadiazole Linked 1,2,3-Triazole Hybrids as Potent EGFR Targeting Antilung Cancer Agents: In Vitro, In Silico, and DFT Studies 喹唑啉-1,3,4-恶二唑连接1,2,3-三唑复合物作为EGFR靶向抗肺癌药物的合成：体外、硅和DFT研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202500049

Sampath peddapelli, Mahadev Dattatray Bandgar, Ravikumar Kapavarapu, Joshodeep Boruwa, Rambabu Palabindela, Sirassu Narsimha

{"title":"Synthesis of Quinazoline-1,3,4-Oxadiazole Linked 1,2,3-Triazole Hybrids as Potent EGFR Targeting Antilung Cancer Agents: In Vitro, In Silico, and DFT Studies","authors":"Sampath peddapelli, Mahadev Dattatray Bandgar, Ravikumar Kapavarapu, Joshodeep Boruwa, Rambabu Palabindela, Sirassu Narsimha","doi":"10.1002/slct.202500049","DOIUrl":"https://doi.org/10.1002/slct.202500049","url":null,"abstract":"This research focuses on the design and synthesis of novel quinazoline-1,3,4-oxadiazole linked 1,2,3-triazoles. Subsequently, it investigates their in vitro inhibitory effects on EGFR kinases and anticancer efficacy against lung cancer cell lines A-549 and H1299. Compared to the primary compound, erlotinib, most tested compounds demonstrated superior efficacy. The compounds 2-(((1-(3,5-difluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)sulfonyl)-5-(quinazoline-5-yl)-1,3,4-oxadiazole, 2-(((1-(3,5-dichlorophenyl)-1H-1,2,3-triazol-4-yl)methyl)sulfonyl)-5-(quinazolin-5-yl)-1,3,4-oxadiazole, and 2-(((1-(4-fluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)sulfonyl)-5-(quinazoline-5-yl)-1,3,4-oxadiazole showed strong anticancer activity against both cancer cell lines with IC50 values ranging from 2.62 ± 0.65 to 4.21 ± 0.24 µM. The compounds exhibited notable kinase inhibitory activity with EGFR IC50 values of 0.34 ± 0.03, 0.36 ± 0.04, and 0.43 ± 0.02 µM, respectively. In Silico docking experiments were conducted to assess the molecular interactions of more potent drugs with the human epidermal growth factor receptor, EGFR (PDB: 4HJO) proteins, which included a co-crystallized ligand (erlotinib). The results indicated that six active compounds exhibited significantly higher binding energies compared to standard medications. SWISS/ADME was used to estimate the in Silico pharmacokinetic profile of potent compounds. Geometric optimization was also used to determine the structural characteristics of compound 2-(((1-(3,5-difluorophenyl)-1H-1,2,3-triazol-4-yl)methyl)sulfonyl)-5-(quinazolin-5-yl)-1,3,4-oxadiazole. The molecular electrostatic potential (MEP) and HOMO-LUMO energy gap were determined.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

α-Aminophosphonates: Antimicrobial, Anti-Inflammatory, Antioxidant Activities, Molecular Docking, and DFT Studies α-氨基膦酸盐：抗菌、抗炎、抗氧化活性、分子对接和DFT研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202500015

Manel Lina Djendi, Chahrazed Benzaid, Malika Berredjem, Ismahene Grib, Rania Bahadi, Seif-Eddine Djouad, Khadidja Otmane Rachedi, Kheir Eddine Ouali, Ajmal R. Bhat, Anissa Acidi

{"title":"α-Aminophosphonates: Antimicrobial, Anti-Inflammatory, Antioxidant Activities, Molecular Docking, and DFT Studies","authors":"Manel Lina Djendi, Chahrazed Benzaid, Malika Berredjem, Ismahene Grib, Rania Bahadi, Seif-Eddine Djouad, Khadidja Otmane Rachedi, Kheir Eddine Ouali, Ajmal R. Bhat, Anissa Acidi","doi":"10.1002/slct.202500015","DOIUrl":"https://doi.org/10.1002/slct.202500015","url":null,"abstract":"Three α-aminophosphonates derived from 2-hydroxybenzaldehyde were synthesized and evaluated their biological activities. The antimicrobial and antibiofilm properties of compounds 1A, 1B, and 1C were evaluated against a range of pathogenic bacteria and fungi, including four Gram-negative bacteria: Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Serratia marcescens; one Gram-positive bacterium: Staphylococcus aureus; and five yeasts of the Candida genus: Candida albicans, Candida kefyr, Candida krusei, Candida lusitaniae, and Candida tropicalis. The antioxidant activity of these compounds was assessed by DPPH (2,2-diphenyl-1-picrylhydrazyl). Determination of the anti-inflammatory activity of the compounds in vitro was carried out using bovine serum albumin (BSA) protein. Computational analysis was carried out using density functional theory (DFT) with the B3LYP 6–31G (d,p) basis set, and the theoretical results were correlated with experimental data. Molecular docking study was carried out to give insights into the interactions of three derivatives with the binding sites of thymidylate kinase (TMK) in S. aureus. Compound 1b uses its phenol group to create a hydrogen bond with the amino acid Gln101. Additionally, its phenyl ring engages in a π-stacking interaction with Tyr100 and Phe66 in the hydrophobic zone of the S. aureus TMK binding site.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ionic Liquids as Green Sustainable Materials in Textiles 离子液体作为绿色可持续纺织品材料

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202405307

Moumita Saha, Dr. Farooq A. Wani, Dr. Manoj K. Banjare, Ambrish Kumar, Ritik Vishwakarma, Dr. Kamalakanta Behera, Dr. Shruti Trivedi

{"title":"Ionic Liquids as Green Sustainable Materials in Textiles","authors":"Moumita Saha, Dr. Farooq A. Wani, Dr. Manoj K. Banjare, Ambrish Kumar, Ritik Vishwakarma, Dr. Kamalakanta Behera, Dr. Shruti Trivedi","doi":"10.1002/slct.202405307","DOIUrl":"https://doi.org/10.1002/slct.202405307","url":null,"abstract":"Textile industry is one of the major pollution causing sector which needs totally an eco-friendly process instead of traditional ones. From harvesting crops or synthesizing fibers which requires very large quantities of water with extreme chemicals, to discarded fabrics causing environmental damages, textile industry requires a complete green processing method. Green solvent like ionic liquids (ILs) are emerging as a new substitute in the textile engineering processes. ILs are formed by mainly organic cations and organic/inorganic anions having many attractive physicochemical properties like high conductivity, low vapor pressure, good thermal stability etc. Here, we have discussed how ILs can be involved in textile processing like coloring of fabric or introducing novel properties, and pollution control. Thus, great efforts are being made worldwide to show a cleaner production structure to decline the toxicity and environmental threat of textile chemicals. Ultimately the goal is to increases sustainability and provides an opportunity to make novel generations of textile processes and also produce high-valued innovative textiles for greater purpose.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Insilico Investigation of the Binding Interaction Mechanism of Vipoglanstat (GS- 248) with Microsomal Prostaglandin E Synthase-1 (mPGES1) and Bovine Serum Albumin (BSA) Vipoglanstat （GS- 248）与微粒体前列腺素E合成酶-1 （mPGES1）和牛血清白蛋白（BSA）结合作用机制的计算机模拟研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202405352

Alanthata Govindan Navaneeth, Subramani Karthikeyan

{"title":"An Insilico Investigation of the Binding Interaction Mechanism of Vipoglanstat (GS- 248) with Microsomal Prostaglandin E Synthase-1 (mPGES1) and Bovine Serum Albumin (BSA)","authors":"Alanthata Govindan Navaneeth, Subramani Karthikeyan","doi":"10.1002/slct.202405352","DOIUrl":"https://doi.org/10.1002/slct.202405352","url":null,"abstract":"Microsomal Prostaglandin E Synthase-1 (mPGES1) is an enzyme involved in the biosynthesis of Prostaglandin E2 (PGE2), a prostanoid and pro-inflammatory lipid mediator that plays a role in both pathological and physiological functions in the human body. Elevated PGE2 levels are associated with inflammation and tissue fibrosis, key characteristics of scleroderma (systemic sclerosis). Consequently, inhibiting mPGES1 may reduce PGE2 production, thereby decreasing the severity of systemic sclerosis. Vipoglanstat (GS-248, (2-[2,6-dichloro-3-[(2,2-dimethylpropanoylamino) methyl] anilino]-6-(2,2-difluoroethoxy)-1-methyl-N-[4-(trifluoromethyl) cyclohexyl] benzimidazole-5-carboxamide), a small molecule in the carboxamide class, is a selective and potent mPGES1 inhibitor with demonstrated anti-inflammatory activity. This study investigates the molecular interactions of GS-248 with mPGES1 and the transport protein BSA using computational techniques such as molecular docking, DFT, molecular dynamics, and PCA analyses. Additionally, we compared the binding affinity of GS-248 to mPGES1 with that of the known inhibitor 4U9. Molecular docking results reveal binding scores of -6.71 kcal mol−1 for the mPGES1-GS248 complex, -7.74 kcal mol−1 for the mPGES1-4U9 complex, and -5.54 kcal mol−1 for the BSA-GS248 complex. These findings suggest that GS-248 exhibits a binding affinity comparable to the reference inhibitor, highlighting its potential as an mPGES1 inhibitor. DFT calculations indicate that binding with mPGES1 and BSA decreases the energy gap of GS-248 from 4.74 to 1.82 eV and 1 eV, respectively, suggesting enhanced drug reactivity at the protein binding sites. Additionally, molecular dynamics simulations confirmed the stability of these protein-drug complexes. In silico toxicity evaluations using Swiss ADME and Protox2 further indicated the potential therapeutic viability of GS-248.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Divergent Access to Furans and Thiophenes by Chalcogenation of 2,3-Dihydrofurans with Elemental Chalcogens 2,3-二氢呋喃与单质硫化物硫代反应对呋喃和噻吩的不同反应

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202501419

Quang Huy Tran, Cao Nguyen Nguyen, Ngoc Lan Chu, Dr. Thai Thanh Thu Bui, Prof. Thi Thu Tram Nguyen, Minh Tu Ha, Prof.Dr. Dinh Hung Mac, Dr. Thanh Binh Nguyen

引用次数: 0

Optimization of Quercetin Extraction from Schisandra Chinensis by an Ultrasound-Assisted Ionic Liquid-Enzyme Composite System and Its Antioxidant Research Analysis 超声辅助离子液酶复合体系提取五味子槲皮素的工艺优化及其抗氧化研究分析

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202500400

Jingwei Hao, Yi Zhou, Xiangkun Zhou, Qiuxuan Li, Yingying Pei, Nan Dong, Yifan Sun, Heming Liu

{"title":"Optimization of Quercetin Extraction from Schisandra Chinensis by an Ultrasound-Assisted Ionic Liquid-Enzyme Composite System and Its Antioxidant Research Analysis","authors":"Jingwei Hao, Yi Zhou, Xiangkun Zhou, Qiuxuan Li, Yingying Pei, Nan Dong, Yifan Sun, Heming Liu","doi":"10.1002/slct.202500400","DOIUrl":"https://doi.org/10.1002/slct.202500400","url":null,"abstract":"In this study, the effects of enzyme addition, ionic liquid concentration, and sonication time on the yield of quercetin in Schisandra chinensis (S. chinensis) were investigated by one-way experiments and their interactions were investigated with enzyme addition, ionic liquid concentration and sonication time as independent variables. The results showed that when the enzyme addition was 16.413%, the ionic liquid was 1-butyl-3-methylimidazolium chloride salt with the concentration of 0.390 mol/L, and the ultrasonication time was 43.770 min, the yield was 0.539 mg/g, which was 8.694 times higher than that of the traditional reflux extraction method. By network pharmacological analysis, 1867 antioxidant targets of quercetin in S. chinensis were screened out.GO and KEGG enrichment analyses indicated that the antioxidant function might be related to the chemical carcinogenesis-reactive oxygen species pathway, PI3K-Akt signalling pathway. The antioxidant activity of quercetin was also investigated by determining the scavenging ability of quercetin on DPPH and hydroxyl radicals. The results showed that the scavenging rates of quercetin on both were 94.510% and 64.922% when the quality concentration of quercetin was 0.06 and 0.4 mg/mL, respectively, and the scavenging rates basically remained unchanged with the increase of concentration.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study on the Construction Mechanism of Porous Titania-Bisphosphonates Hybrid Materials 多孔钛-双膦酸盐杂化材料构建机理研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202500174

Sheng Wu, Shuai Zhang, Weibin Jiang, Johan Alauzun, Qing Kang, Chongyang Xu, Dejian Wang, Qishuo Du, Peijie Yao, Jifan Dai, Yanhui Wang

引用次数: 0

Preparation and Characterization of Silver-Loaded Magnetic Activated Carbon Produced from Crataegus Monogyna for Antimicrobial and Antioxidant Applications 山楂载银磁性活性炭的制备及抗氧化性能研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-04-23 DOI: 10.1002/slct.202405558

Erdal Ertaş, Serap Doğan, Ayşe Baran, Mehmet Fırat Baran, Murat Evcil, Barış Kurt, Zübeyir Güneş, Kadir Sinan Aslan

{"title":"Preparation and Characterization of Silver-Loaded Magnetic Activated Carbon Produced from Crataegus Monogyna for Antimicrobial and Antioxidant Applications","authors":"Erdal Ertaş, Serap Doğan, Ayşe Baran, Mehmet Fırat Baran, Murat Evcil, Barış Kurt, Zübeyir Güneş, Kadir Sinan Aslan","doi":"10.1002/slct.202405558","DOIUrl":"https://doi.org/10.1002/slct.202405558","url":null,"abstract":"Secondary metabolites from several plant species have been used to cure various illnesses. Current advances allowed green synthesis nanoparticle manufacturing of metal salts from plant sources. This study involves binding activated carbon obtained from the Crataegus monogyna plant to magnetic nanoparticles and coating the resulting magnetic activated carbon nanocomposite with Ag ions (CMAC/MNPs-Ag) to produce a biomedical nanobiological material. Various techniques such as SEM, EDX, XRD, FTIR, UV-Vis, VSM, DLS, and zeta potential were used to characterize synthesized nanocomposites. CMAC/MNPs-Ag nanocomposite demonstrated activity in several processes of antioxidant activity tests. DPPH and CUPRAC activities of CMAC/MNPs-Ag nanocomposite were measured as 90.21 ± 0.42 and 46.73 ± 0.108 mg TE/g, respectively, while total phenolic content was measured as 27.15 ± 0.381 mg GAE/g. Finally, the antibacterial activity of CMAC/MNPs-Ag nanocomposite was evaluated against Escherichia coli and Staphylococcus aureus by microdilution and disk diffusion techniques. The antimicrobial activity of CMAC/MNPs-Ag nanocomposite was determined using microdilution and disk diffusion techniques. For Escherichia coli, microdilution and disk diffusion were measured as 1.17 µg mL−1 and 12 mm, respectively, while for Staphylococcus aureus, microdilution and disk diffusion were measured as 2.34 µg mL−1 and 10 mm, respectively.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 16","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-04-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143861722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0