ChemistrySelectPub Date : 2025-07-30DOI: 10.1002/slct.202502197
Ivan H. Hameed, Maher K. Ali, Shinwar A. Idrees
{"title":"Co-Sensitization Effect of CNQDs and Anthocyanin on TiO2 for High-Efficiency Dye-Sensitized Solar Cells: Experimental and Theoretical Insights","authors":"Ivan H. Hameed, Maher K. Ali, Shinwar A. Idrees","doi":"10.1002/slct.202502197","DOIUrl":"https://doi.org/10.1002/slct.202502197","url":null,"abstract":"<p>This study investigates the fabrication and characterization of natural pigment and carbon nitride quantum dots (CNQDs) co-sensitized solar cells. The results showed that CNQDs@TiO<sub>2</sub> significantly improved light absorption and charge transfer properties. The effects of pH and temperature were examined to assess their influence on DSSC performance. It was found that an acidic medium yields the best results, with an optimal temperature of 25 °C. Photovoltaic measurements revealed a significant efficiency improvement in DSSCs, increasing from 2.7% for anthocyanin@TiO<sub>2</sub> to 8.6% when modified with anthocyanine & CNQDs@TiO<sub>2</sub>. In addition, the fill factor was improved from 0.46 to 0.63, respectively. The structural composition, size, morphology, and optical properties of CNQDs@TiO<sub>2</sub> were characterized using FTIR, DRS, XRD, FESEM, EDX, and TEM analytical techniques. DFT calculations were employed to learn more about the mechanism, efficiency, and photovoltaic properties of synthesized DSSCs. The theoretical results agree with experimental data in which the anthocyanine & CNQDs @ TiO<sub>2</sub> system is more efficient. CNQDs can be mediators, broadening the spectrum of light harvesting and providing extra bands that facilitate electron transitions.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChemistrySelectPub Date : 2025-07-30DOI: 10.1002/slct.202501463
Ishan Shrestha, Paratpar Sarkar
{"title":"Green Synthesis of Silver and Copper Oxide Nanoparticles From Leaf, Stem, and Root Extract of Ocimum Tenuiflorum: Biochemical Analysis and Molecular Docking Study against Potential Cancer Receptors","authors":"Ishan Shrestha, Paratpar Sarkar","doi":"10.1002/slct.202501463","DOIUrl":"https://doi.org/10.1002/slct.202501463","url":null,"abstract":"<p>Nanotechnology has grown significantly and keeps advancing quickly, with more applications aimed at improving human health and meeting different needs. Overexpression of certain receptors is seen in most cases of cancer. Targeting these receptors with nanoparticles provides a promising way to treat patients with resistant cancers. This study aimed to synthesize copper oxide (CuO NPs) and silver nanoparticles (Ag NPs) using leaf, stem, and root extracts of <i>Ocimum tenuiflorum</i>, with ethanol as the solvent. The researchers characterized the nanoparticles using ultraviolet–visible (UV–Vis) and Fourier transform infrared (FT-IR) spectroscopy. The phytochemicals in the extracts were analyzed to identify secondary metabolites. A molecular docking study was conducted to assess the binding interactions between the phytochemicals in the nanoparticles and three potential cancer targets: estrogen, gonadotropin-releasing hormone, and somatostatin receptors. The results confirmed the successful synthesis of CuO and Ag NPs from different parts of <i>Ocimum tenuiflorum</i>. Ag NPs showed a characteristic UV–Vis peak at 419–422 nm, while CuO NPs had a peak at 262 nm. FT-IR analysis showed that functional groups from secondary metabolites like polyphenols and terpenoids were involved in nanoparticle synthesis and capping. Molecular docking revealed strong binding interactions of cirsimaritin with somatostatin (binding energy: −96.8 kJ/mol) and of rosmarinic acid with the same receptor (−88.4 kJ/mol). Overall, the study concludes that cirsimaritin and rosmarinic acid in Ag and CuO NPs effectively target somatostatin and other receptors. This requires further in vitro studies to explore their therapeutic potential against various cancer cell lines.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725752","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChemistrySelectPub Date : 2025-07-30DOI: 10.1002/slct.202502967
Zhijing Liang, Changle Wang, Jiong Sun, Cuizhen Bai, Dr. Muhammad Kamran, Dr. Salman Qadir, Prof. Dr. Runtong Zhang, Prof. Dr. Jinxiao Dou, Prof. Dr. Shao-Tao Bai
{"title":"Retest Parameters for Single-Cobalt-Based-Catalysts for Dry Reforming of Methane","authors":"Zhijing Liang, Changle Wang, Jiong Sun, Cuizhen Bai, Dr. Muhammad Kamran, Dr. Salman Qadir, Prof. Dr. Runtong Zhang, Prof. Dr. Jinxiao Dou, Prof. Dr. Shao-Tao Bai","doi":"10.1002/slct.202502967","DOIUrl":"https://doi.org/10.1002/slct.202502967","url":null,"abstract":"<p>Cobalt-based catalysts are promising and yet to be thoroughly explored candidates for Dry reforming of methane (DRM). In this paper, we retested the crucial parameters including supports, cobalt loadings, and calcination temperatures for single cobalt-metal-based catalysts for DRM. X-ray Diffraction (XRD), X-ray photoelectron spectroscopy (XPS), CO<sub>2</sub> programmed desorption (CO₂-TPD), thermogravimetric analysis (TG) and scanning electron microscope (SEM) experiments were applied to characterize the textural properties, cobalt species distribution and coke resist performance. Analysis of the physical/chemical properties in relation to the performance implies that suitable amounts of Co<sup>3+</sup> species, oxygen vacancies, and particle size are crucial factors for the optimization of Co-based DRM catalysts. The optimized catalyst 8Co/MgAl<sub>2</sub>O<sub>4</sub>(600) with MgAl<sub>2</sub>O<sub>4</sub> support, 8 wt% Co and 600°C calcination temperature gave a coke deposition of 15.02% and 66% and 75% conversions of CH<sub>4</sub> and CO<sub>2</sub>, respectively, with H₂/CO ratios stabilized at ca. 0.83 after 30 h of operation at 700°C.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Binary Mixture of TOPO-DA DES and Dichloromethane: Physicochemical–Structural Aspects and Extraction Scrutiny of Eu (III) /Y (III)","authors":"Dibyajyoti Swain, Pratyasha Panda, Bibek Dash, Ranjan Lopamudra Bhutia, Sujata Mishra","doi":"10.1002/slct.202501199","DOIUrl":"https://doi.org/10.1002/slct.202501199","url":null,"abstract":"<p>Deep eutectic solvents (DESs), consisting of a mixture of two compounds, are emerging as a new generation of solvents. The binary mixture of hydrophobic DES based on tri-<i>n</i>-octylphosphine oxide (TOPO) and decanoic acid (DA), and its mixture with dichloromethane (DCM), has been considered in the present study to know about the molecular interaction that exists in the system based on their physico-chemical properties and DFT analysis. Its use for the extraction of europium and yttrium has been examined. In this connection, the density, molar volume, apparent molar volume, dielectric constant, refractive index, and ultrasonic velocity and their excess properties have been determined. It has been observed that on increasing the mole fraction of DES density and dielectric constant of the mixture decreased, while values of molar volume, volume fraction, apparent molar volume, refractive index, and ultrasonic velocity increased. The observed properties ensure that weak interactions, such as nonspecific or hydrogen bonding, exist in the binary system. The interaction between TOPO-DA DES and dichloromethane is weak, as observed from DFT analysis in terms of interaction energy. FTIR and Raman spectral studies show a slight shifting of peaks, supporting weak interaction. Binary mixture of DES + DCM shows better extraction efficiency with europium than with yttrium.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChemistrySelectPub Date : 2025-07-30DOI: 10.1002/slct.202503519
Nida Ük, Nil Ürküt, İbrahim Yağız Coşkun, Ahmet Gamlı, Esra Okur, Caner Ünlü
{"title":"Dopant-Driven Metal Ion Response in Carbon Dots: The Role of Excitation Wavelength in Selective Sensing and Potential Design of an Eco-Friendly ATP Sensor","authors":"Nida Ük, Nil Ürküt, İbrahim Yağız Coşkun, Ahmet Gamlı, Esra Okur, Caner Ünlü","doi":"10.1002/slct.202503519","DOIUrl":"https://doi.org/10.1002/slct.202503519","url":null,"abstract":"<p>In this study, nitrogen- and boron-doped carbon dots (CDs) were synthesized via a microwave-assisted method and evaluated for metal ion sensing and ATP detection. The work investigated how surface and core states influence photophysical behavior and selective quenching. FTIR confirmed distinct carboxyl, amine, and hydroxyl surface functionalities for each CD variant. Spectroscopic analysis revealed excitation-dependent emissions, linking specific radiative transitions to functional groups and core states. Notably, Cu<sup>2</sup>⁺ quenched 80% of fluorescence primarily at shorter excitation wavelengths (300 nm), indicating strong surface-state interactions, while Ag⁺ induced 65% quenching at longer wavelengths (450 nm) through core-state interactions. Boron-doped CDs displayed at least a 20-fold fluorescence enhancement upon exposure to Mg<sup>2</sup>⁺, Zn<sup>2</sup>⁺, and Cd<sup>2</sup>⁺ at 300 nm, attributed to surface passivation. In ATP sensing assays, the CDs’ high sensitivity to Cu<sup>2</sup>⁺ and ATP's affinity for copper ions enabled detection via absorption and fluorescence spectroscopy. These results demonstrate that tuning excitation wavelength modulates sensor selectivity, showing doped CDs as cost-effective, eco-friendly platforms for wavelength-specific ion and biomolecule detection. The combined quenching and enhancement behaviors emphasize the critical role of surface and core state engineering in achieving wavelength-specific responses. This study provides a foundation for developing low-cost, environmentally friendly sensors based on doped CDs with tunable selectivity.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Detailed Insights Into Water-Assisted Approaches Toward the Synthesis of Pyrazole Derivatives","authors":"Shubham Sharma, Vaishali, Swati Rani, Ensaf Alwan, Cédric Spitz, Sobhi M. Gomha","doi":"10.1002/slct.202501509","DOIUrl":"https://doi.org/10.1002/slct.202501509","url":null,"abstract":"<p>Green synthesis is important in organic synthesis nowadays. Increasing awareness of the need for eco-friendly technology has led to the use of green techniques in precision chemical and pharmaceutical development. Alternative reaction media that reduce the problems of volatile organic solvents are also gaining popularity. Innovation in reaction media for eco-friendly, sustainable organic synthesis and the development of important organic heterocycles. Pyrazole and its derivatives are preferred organic heterocycle structures for lead compound identification in the discovery of new synthetic pharmaceutical molecules and other key possibilities. Numerous commercial drugs, such as sildenafil, rimonabant, and celecoxib, in biological and preclinical trials demonstrate the therapeutic breadth of this pharmacological scaffold category. As a green solvent, water is essential for pyrazole derivative synthesis and a convenient reaction medium for organic chemists. This review discusses water's eco-friendly role in pyrazole derivative synthesis.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Exploration of Dithiocarbamate-Linked Kojic Acid–Piperazine Hybrids: Synthesis, Characterization, and Biological Screening","authors":"Asst. Prof Gülşah Karakaya, Assoc. Prof İsmail Öztürk, Assoc. Prof Fadime Aydin Köse, Şerife Ezgi Çetin, Assoc. Prof Gül Özkan, Erdal Kurt, Prof.Dr. Muhittin Aygün, Prof.Dr. Mutlu Dilsiz Aytemir","doi":"10.1002/slct.202503309","DOIUrl":"https://doi.org/10.1002/slct.202503309","url":null,"abstract":"<p>Developing drug candidates with multiple mechanisms of action is a strategy to overcome drug resistance, the main obstacle in effectively treating infections. This study focused on the design and synthesis of hybrid compounds containing kojic acid scaffold and substituted phenylpiperazine groups linked via a dithiocarbamate moiety. Structural elucidation was achieved using spectroscopic techniques and elemental analysis. The single-crystal X-ray diffraction (SCXRD) analysis and density functional theory (DFT)-based geometry optimization were performed. Antimicrobial activities were assessed against bacteria and fungi through disk diffusion and microdilution techniques. Their influence on biofilm production was measured spectrophotometrically. Additionally, the antioxidant potential was screened using the 2,2’-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS+) radical decolorization assay and the 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. According to bioactivity results, compound <b>3</b>—named (5-hydroxy-4-oxo-4<i>H</i>-pyran-2-yl)methyl 4-(3-chlorophenyl)piperazine-1-carbodithioate—exhibited the most potent antifungal activity against clinical isolates of <i>Candida albicans</i> with a mean minimum inhibitory concentration (MIC) of 64 µg/mL and a mean inhibition zone diameter value of 14–15 mm. Also, compound <b>4</b> demonstrated the highest biofilm inhibition rates (70.5%) against <i>C. albicans</i> and displayed strong antioxidant capacity against ABTS+ (IC<sub>50</sub> = 8.75 µg/mL). This study's results could help in creating new drug candidates targeting bacterial infections linked to biofilms that require strong antioxidant activity.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChemistrySelectPub Date : 2025-07-29DOI: 10.1002/slct.202502359
Sambasivarao Kotha, Kunkumita Jena
{"title":"Metal-Free and Thiol-Free Approach to Diverse Thiacyclophanes","authors":"Sambasivarao Kotha, Kunkumita Jena","doi":"10.1002/slct.202502359","DOIUrl":"https://doi.org/10.1002/slct.202502359","url":null,"abstract":"<p>Here, we report various thiacyclophane derivatives starting with arylmethyl bromides and potassium thioacetate. We conducted a controlled synthesis of thiacyclophanes dimer, trimer, and tetramer by changing the concentration of reactants. The reaction conditions were optimized to improve the selectivity. All the reactions were performed in low dilution without using the high dilution technique, the only known direct synthetic method for these thiacyclophanes. The structures of various thiacyclophanes were confirmed by NMR studies and further supported by single-crystal X-ray diffraction data.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144716600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
ChemistrySelectPub Date : 2025-07-29DOI: 10.1002/slct.202503240
Ran Liu, Chongtian Wu, Yuting Luan, Shuang Sheng, Jinling Yin
{"title":"Bimetallic Ni@Cu Nanorod Arrays for Electrochemical Oxidation of Hydrazine","authors":"Ran Liu, Chongtian Wu, Yuting Luan, Shuang Sheng, Jinling Yin","doi":"10.1002/slct.202503240","DOIUrl":"https://doi.org/10.1002/slct.202503240","url":null,"abstract":"<p>The development of efficient non-precious metal catalysts for the hydrazine (N<sub>2</sub>H<sub>4</sub>) oxidation reaction (HzOR) is critical to improve the performance of direct hydrazine fuel cells (DHFCs). In this study, Ni-decorated Cu nanorod arrays were directly grown on Cu foam (Ni@Cu/CF) via a sequential process of electrochemical anodization, chemical reduction, and galvanostatic electrodeposition. This work utilizes the synergistic effect at Cu–Ni heterointerfaces and the high specific surface area combined with rapid electron transport ability provided by the one-dimensional nanorod architecture to significantly enhance the HzOR performance. The electrocatalytic performance of the binary Ni@Cu/CF electrode for the HzOR is superior to those of the single-metal electrodes (Cu/CF and Ni/CF), manifested as a higher current density (<i>j </i>= 278.2 mA cm<sup>−2</sup> at −0.6 V) and lower onset potential (<i>E</i><sub>on</sub> = −1.08 V). Ni@Cu/CF exhibits excellent stability, maintaining 76.9% and 77.1% of its initial activity after 26 h of continuous operation at −0.9 and −0.8 V, respectively. The Ni@Cu/CF also achieves nearly 100% Faradaic efficiency. The favorable electrocatalytic properties of Ni@Cu/CF make it suitable as a potential catalyst for the HzOR.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144716602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"“Bimetallic Nanoparticles: A Comprehensive Review of Synthesis Methods and Their Potential Application”","authors":"Madhuri Goswami, Deepti Pal, Mithun Kumar Ghosh, Sonu Dwivedi, Sandip Kumar Chandraker","doi":"10.1002/slct.202501493","DOIUrl":"https://doi.org/10.1002/slct.202501493","url":null,"abstract":"<p>The performance limitations of monometallic nanoparticles, such as reduced stability, limited catalytic efficiency, and susceptibility to deactivation, pose significant challenges in various scientific and industrial applications. To address these issues, bimetallic transition metal nanoparticles (BTENs) have emerged as promising alternatives due to their unique structural and functional properties. Composed of two different metal elements, BTENs exhibit synergistic effects that enhance their catalytic, electronic, magnetic, and optical characteristics beyond those of monometallic counterparts. Their synthesis can be achieved through diverse methods, including chemical reduction, sol–gel, hydrothermal, microemulsion, and green techniques involving plant extracts or microorganisms. BTENs offer tunable catalytic activity, improved durability, and higher efficiency, making them suitable for energy storage devices (e.g., batteries, supercapacitors), sensors, and environmental monitoring. Additionally, their tailored electronic structure facilitates high performance in biomedical applications such as drug delivery, imaging, and therapy. Their magnetic and optical properties further support advanced techniques like MRI, magnetic hyperthermia, surface-enhanced Raman spectroscopy (SERS), and photothermal therapy.</p>","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 29","pages":""},"PeriodicalIF":2.0,"publicationDate":"2025-07-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144725576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}