ChemistrySelect最新文献_第3页

Synthesis, Characterization, and Biological Studies of Organometallic Compounds of Re(I) with 2-(5-(4-Nitrophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzo[d]thiazole Based Derivatives Re(I)与2-（5-（4-硝基苯）-3-苯基-4,5-二氢- 1h -吡唑-1-基）苯并噻唑衍生物有机金属化合物的合成、表征及生物学研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202502109

Aelvish D. Padariya, Nirbhay K. Savaliya, Hitesh M. Parekh, Bhupesh S. Bhatt, Vaibhav D. Bhatt, Mohan N. Patel

{"title":"Synthesis, Characterization, and Biological Studies of Organometallic Compounds of Re(I) with 2-(5-(4-Nitrophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzo[d]thiazole Based Derivatives","authors":"Aelvish D. Padariya, Nirbhay K. Savaliya, Hitesh M. Parekh, Bhupesh S. Bhatt, Vaibhav D. Bhatt, Mohan N. Patel","doi":"10.1002/slct.202502109","DOIUrl":"https://doi.org/10.1002/slct.202502109","url":null,"abstract":"Organometallic Re(I) complexes and substituted 2-(5-(4-nitrophenyl)-3-phenyl-4,5-dihydro-1H-pyrazol-1-yl)benzo[d] thiazole were effectively synthesized and characterized using a variety of spectroscopic techniques. Through viscosity measurements and absorption titration tests, their interaction with CT-DNA was investigated. An intercalation binding mode was discovered, and molecular docking analysis confirmed this finding. Additionally, protein-binding affinity was assessed by BSA binding assays. Tests of the synthesized compounds' antibacterial activity against three Gram-negative and two Gram-positive strains showed that Re(I) complexes exhibit more potent antibacterial activities than free ligands. SwissADME was used to predict pharmacokinetic parameters. DFT computations were used to calculate the compounds' molecular orbital energies. Furthermore, the anticancer potential was tested against MCF-7 cells, and cytotoxicity was evaluated using a brine shrimp lethality assay. The compounds with -F and -OCH3 groups, complexes C4 and C2, have the lowest IC50 values (92.48 µg/mL and 98.76 µg/mL, respectively). All complexes are more potent than carboplatin, with an IC50 value of 165.28 µg/mL, and are closer to cisplatin (80.00 µg/mL). Pyrazole and thiazole moieties in broaden the range of biological activities. Especially in anticancer therapy, where their capacity to interact with many cellular targets might enhance efficacy and decrease resistance, these drugs have demonstrated encouraging outcomes.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sustainable Bio-Fabrication of Chromium (III) Oxide Nanoparticles for Efficient Removal of 2,4-Dichlorophenoxyacetic Acid: A Response Surface Optimization Approach 可持续生物制备氧化铬纳米颗粒高效去除2,4-二氯苯氧乙酸：响应面优化方法

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202501754

Waseem Ahmad, Sarfaraz Ahmed, Mahvish Shameem, Sanjay Kumar, Shoeb Anwar Ansari

{"title":"Sustainable Bio-Fabrication of Chromium (III) Oxide Nanoparticles for Efficient Removal of 2,4-Dichlorophenoxyacetic Acid: A Response Surface Optimization Approach","authors":"Waseem Ahmad, Sarfaraz Ahmed, Mahvish Shameem, Sanjay Kumar, Shoeb Anwar Ansari","doi":"10.1002/slct.202501754","DOIUrl":"https://doi.org/10.1002/slct.202501754","url":null,"abstract":"The pesticide 2, 4-dichlorophenoxyacetic acid (2, 4-D) is recognized as a formidable organic contaminant due to its carcinogenic and toxic behavior. Due to its high solubility and resilience in both chemical and biological environments, it is tough to remove from its aqueous solution. The goal of the present investigation is to evaluate the breakdown of the 2, 4-D herbicide in aqueous solution by employing a nano photocatalyst. For this purpose, 2, 4-D underwent degradation utilizing the bio-fabricated chromium oxide nanoparticles (Cr2O3 NPs). In the bio-fabrication of Cr2O3 NPs Raphunus sativus leaf extract is used as the green source. The study also evaluated the impacts of various operational parameters, that is, catalyst dose (g/L), pollutant concentration (ppm), and pH on the photocatalytic degradation efficiency of the photocatalyst. The result of this investigation clearly established that the bio-fabricated Cr2O3 NPs efficiently remove the pollutants from the aqueous solution. Under optimized conditions (catalyst dose: 2 g/L, pesticide concentration: 15 mg/L, and pH: 4), 73% of 2, 4-D degraded within 90 min.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Activated Carbon Modified with Oxalic Acid as a Loader for Co(II)@AC Catalyst in the Oxidation of 1-(4-Chlorophenyl)-pyrazolidin-3-one to 1-(4-Chlorophenyl)-1H-pyrazol-3-ol by Air 草酸改性活性炭作为Co(II)@AC催化剂空气氧化1-（4-氯苯基）-吡唑烷-3- 1制1-（4-氯苯基）- 1h -吡唑醇-3-醇的装填剂

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202501335

Yu-cheng Jiang, Bao-guang Zhu, Xiang-li Long

{"title":"Activated Carbon Modified with Oxalic Acid as a Loader for Co(II)@AC Catalyst in the Oxidation of 1-(4-Chlorophenyl)-pyrazolidin-3-one to 1-(4-Chlorophenyl)-1H-pyrazol-3-ol by Air","authors":"Yu-cheng Jiang, Bao-guang Zhu, Xiang-li Long","doi":"10.1002/slct.202501335","DOIUrl":"https://doi.org/10.1002/slct.202501335","url":null,"abstract":"The production of 1-(4-chlorophenyl)-1H-pyrazol-3-ol by oxidizing 1-(4-chlorophenyl)- pyrazolidin-3-one with H2O2 suffers from some shortcomings. The oxidation of 1-(4-chlorophenyl)-pyrazolidin-3-one to 1-(4-chlorophenyl)-1H-pyrazol-3-ol can be realized by air catalyzed with Co(II)@AC (prepared by supporting cobalt(II) on activated carbon). Air is a good substitute for H2O2 because it can minimize the cost, hazards, and pollution, which is beneficial to the improvement of the production process for pyraclostrobin. In this study, activated carbon has been modified by H2C2O4 solution to improve the catalytic performance of Co(II)@AC. The experiments indicate that the best carbon is made by heating the carbon at 300 °C for 3 h with a heating rate of 5 °C/min in N2 after being soaked in 0.4 mol/L H2C2O4 solution at 50 °C for 12 h with an L/S ratio of 40/1 mL/g. The 1-(4-chlorophenyl)-1H-pyrazol-3-ol concentration obtained by Co(II)@AC immobilized on the optimized carbon is 39.39% over that catalyzed by Co(II)@AC loaded on the original carbon. Characterization results reveal that modification with H2C2O4 increases the specific surface area and enhances the acidity on the carbon surface. The oxidation rate of 1-(4-chlorophenyl)-pyrazolidin-3-one is primarily determined by the physical structure. The selectivity toward 1-(4-chlorophenyl)-1H-pyrazol-3-ol is mainly influenced by the chemical characteristics.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hydrogen Evolution by an All-Solid-State Z-Scheme WO3 /Cu3P Photocatalytic Water Splitting System 全固态z型WO3 /Cu3P光催化水分解体系析氢研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202500001

Han Yang, Yujia Zhang, Shiqiu Zhang, Qingqing Li, Ying Liang, Kang Chen, Dongxu Pan, Yanfei Fan, Prof. Guanwei Cui

{"title":"Hydrogen Evolution by an All-Solid-State Z-Scheme WO3 /Cu3P Photocatalytic Water Splitting System","authors":"Han Yang, Yujia Zhang, Shiqiu Zhang, Qingqing Li, Ying Liang, Kang Chen, Dongxu Pan, Yanfei Fan, Prof. Guanwei Cui","doi":"10.1002/slct.202500001","DOIUrl":"https://doi.org/10.1002/slct.202500001","url":null,"abstract":"Photocatalytic water splitting for hydrogen (H₂) evolution represents a pivotal strategy for sustainable energy production. Tungsten trioxide (WO3) is one of the most investigated materials in the semiconductor photocatalysis research field. However, the pure WO3 cannot perform the photocatalytic water splitting reaction because of its unsuitable band structure. In this study, to solve the aforementioned issues, we construct an all-solid-state Z-scheme WO₃/Cu₃P heterojunction photocatalyst to address the limitations of single-component systems. The photocatalytic activity testing results showed that when the loading amount of Cu3P was 10% (mass ratio), WO₃/Cu₃P exhibited the highest photocatalytic activity for hydrogen production. Under the optimized reaction conditions, the synthesized WO₃/Cu₃P obtained a remarkable hydrogen evolution rate was about 50 µmol·g⁻¹·h⁻¹ when irradiated by a Xe lamp, without employing any sacrificial agents. The apparent quantum efficiency is about 0.66%. The photoelectrochemical test and luminescent spectrum results confirmed that the incorporation of Cu3P nanoparticles enhances the transport and separation efficiency of photogenerated carriers, endowing WO3 with the ability to produce hydrogen by photocatalytic water splitting. This work provides a new strategy for the design and synthesis of a phosphorus-based Z-scheme heterostructure photocatalyst.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ricinodendron heudelotii Almond Extract as a Novel Green Corrosion Inhibitor for XC70 Steel in Acidic Medium 蓖麻杏仁提取物作为XC70钢在酸性介质中的新型绿色缓蚀剂

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202501197

Katia Nasri, Nadia Ait Ahmed, Hamida Kermoune Issaadi, Ahmed Hichem Hamzaoui, Nabila Aliouane, Atmane Djermoune, Carine Chassigneux, Marielle Eyraud

{"title":"Ricinodendron heudelotii Almond Extract as a Novel Green Corrosion Inhibitor for XC70 Steel in Acidic Medium","authors":"Katia Nasri, Nadia Ait Ahmed, Hamida Kermoune Issaadi, Ahmed Hichem Hamzaoui, Nabila Aliouane, Atmane Djermoune, Carine Chassigneux, Marielle Eyraud","doi":"10.1002/slct.202501197","DOIUrl":"https://doi.org/10.1002/slct.202501197","url":null,"abstract":"In recent years, there has been growing interest in the use of safe, non-polluting substances, due to increased environmental awareness and stricter environmental protection regulations. This development has led to the emergence of a new class of corrosion inhibitors, known as green corrosion inhibitors. The present study aims to evaluate the inhibitory effect of different concentrations of Ricinodendron heudelotii (RHA) almond extract on the corrosion of XC70 mild steel in a 0.5 M hydrochloric acid (HCl) solution. The evaluation was performed using weight loss measurements, electrochemical techniques, and surface characterization methods. Potentiodynamic polarization tests revealed that RHA functions as a mixed-type inhibitor. Electrochemical impedance spectroscopy (EIS) tests showed that increasing the extract concentration leads to higher charge transfer resistance and lower double-layer capacitance. The adsorption of the inhibitor onto the steel surface followed the Langmuir isotherm model, and surface characterization confirmed the formation of a protective RHA layer. The results demonstrate that RHA is an effective corrosion inhibitor, achieving a maximum inhibition efficiency of 92% at a concentration of 1.2 g/L.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile Hydrothermal Synthesis of Nb-Doped WS2/WO3 Nanostructures: Insights into Photoluminescence and Electronic Properties 水热合成掺杂铌的WS2/WO3纳米结构：对光致发光和电子性能的研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202405246

Prarbdh Bhatt, Vipin Kumar, Rakesh K. Mishra, Nilanjan Halder

引用次数: 0

Molecular Screening and Free Energy Calculations-Based Exploration of Medicinal Phytocompounds Chemical Space to Abrogate G9R-E4R Complex from Monkeypox: A Current Global Health Threat 基于分子筛选和自由能计算的药用植物化合物化学空间探索：从猴痘中去除G9R-E4R复合物：当前全球健康威胁

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202405478

Muhammad Suleman, Hadiqa Ejaz, Yasir Waheed, Zahid Hussain, Arshad Iqbal, Abbas Khan, Hadi M. Yassine, Sergio Crovella

{"title":"Molecular Screening and Free Energy Calculations-Based Exploration of Medicinal Phytocompounds Chemical Space to Abrogate G9R-E4R Complex from Monkeypox: A Current Global Health Threat","authors":"Muhammad Suleman, Hadiqa Ejaz, Yasir Waheed, Zahid Hussain, Arshad Iqbal, Abbas Khan, Hadi M. Yassine, Sergio Crovella","doi":"10.1002/slct.202405478","DOIUrl":"https://doi.org/10.1002/slct.202405478","url":null,"abstract":"The current monkeypox virus outbreak is probably linked with the novel substitutions in the G9R protein of the replication complex. The G9R-E4R interface act as a potential druggable site for the inhibition of monkeypox replication. Therefore, we employed computational methods to explore potential natural products to inhibit the G9R interface. Our results revealed that among the 5230 compounds only four compounds (top hit 1-4) reported excellent docking scores of -8.96 kcal/mole, -8.33 kcal/mol, -7.98 kcal/mol and -7.85 kcal/mol respectively. However, the reported KD value were -7.68 kcal/mol, -7.05 kcal/mol, -7.53 kcal/mol, and -7.77 kcal/mol respectively. The selected lead compounds exhibited consistent dynamics in all-atoms simulations, reflects their robustness and suitability for engaging effectively with the interface residues. Furthermore, the binding free energy was calculated to be -47.86 kcal/mol for the top hit 1 complex, -45.51 kcal/mol for the top hit 2 complex, -41.63 kcal/mol for the top hit 3 complex, and -43.81 kcal/mol for the top hit 4 complex. These compounds also showed favorable pharmacokinetic properties with minimal toxicity risks. The results indicate that compounds top hit 1-4 demonstrate a higher pharmacological potential against the G9R protein of monkypox virus, suggesting immediate experimental testing to assess their clinical viability.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Preparation of CSS-BC/g-C3N4 Composite and Its Adsorption Study on Methylene Blue CSS-BC/g-C3N4复合材料的制备及其对亚甲基蓝的吸附研究

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-30 DOI: 10.1002/slct.202500142

Chenyu Ma, Prof. Huiwei Liao, Dr. Qiulin Deng, Fangfang Yang, Tao Qin

{"title":"Preparation of CSS-BC/g-C3N4 Composite and Its Adsorption Study on Methylene Blue","authors":"Chenyu Ma, Prof. Huiwei Liao, Dr. Qiulin Deng, Fangfang Yang, Tao Qin","doi":"10.1002/slct.202500142","DOIUrl":"https://doi.org/10.1002/slct.202500142","url":null,"abstract":"In this study, a novel composite material, denoted as CSS-BC/g-C3N4, was synthesized by combining camphor seed shells-biochar (CSS-BC) with graphitic carbon nitride (g-C3N4), which was synthesized from melamine. The motivation behind this study stems from the growing demand for efficient and eco-friendly materials to remove organic dyes from aqueous environments. Traditional biomass raw materials, such as coconut shells, walnut shells, pomelo peels, and wheat straw, are often characterized by highly demanding acquisition conditions and high costs of procurement, which consequently limit their availability. In contrast, CSS-BC, derived from abundant camphor seed shells, offers a low-cost alternative. Moreover, the introduction of g-C3N4 can effectively enhance the removal capacity of methylene blue(MB) from aqueous solutions by the composite material. By integrating these two materials, we aim to address the limitations of existing adsorbents and develop a more effective and environmentally friendly solution. The material was subjected to a thorough characterization employing X-ray diffraction (XRD), scanning electron microscopy (SEM), Fourier transform infrared spectroscopy (FTIR), and X-ray photoelectron spectroscopy (XPS). The adsorption efficacy of CSS-BC/g-C3N4 toward MB was systematically assessed under a variety of conditions, including different ratios, pH levels, contact times, and initial MB concentrations, resulting in a maximum adsorption capacity of 290.012 mg/g. The adsorption kinetics of the material were found to align well with the pseudo-second-order model, and the adsorption isotherm data were well described by the Langmuir model, with a coefficient of determination (R2) of 0.910. This research presents an efficient material for the removal of organic dyes from aqueous environments and offers innovative insights into the development of eco-friendly materials.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144179061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Investigation of the Effects of Solvents and Temperature on the Aggregation, Binding, and Phase Partitioning Nature of Triton X-100 with Promazine Hydrochloride 溶剂和温度对Triton X-100与盐酸丙嗪的聚集、结合和相分配性质的影响

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-29 DOI: 10.1002/slct.202501054

Ashraful Alam, Md. Abu Taleb, Md. Masum Reza, Shamim Mahbub, Javed Masood Khan, Muhammad Wajid Ullah, Shahed Rana, Md. Anamul Hoque

{"title":"Investigation of the Effects of Solvents and Temperature on the Aggregation, Binding, and Phase Partitioning Nature of Triton X-100 with Promazine Hydrochloride","authors":"Ashraful Alam, Md. Abu Taleb, Md. Masum Reza, Shamim Mahbub, Javed Masood Khan, Muhammad Wajid Ullah, Shahed Rana, Md. Anamul Hoque","doi":"10.1002/slct.202501054","DOIUrl":"https://doi.org/10.1002/slct.202501054","url":null,"abstract":"Herein, the aggregation, binding, and phase partitioning nature of triton X-100 (TX-100) with promazine hydrochloride (PMZ) have been examined applying spectroscopic and cloud point measurement methods. The PMZ mediated aggregation of TX-100 was found to be disfavored with the elevation of temperature. The binding constant (Kb) of the complexation of TX-100 with PMZ was evaluated applying Benesi–Hildebrand (BH) plot, where the Kb values showed the dependency on solvent composition and experimental temperature. Cloud point (CP) of TX-100 + PMZ mixture was noticed to be reliant on both concentration and solvent variation. The micellization and complexation of the TX-100 + PMZ system in all the investigated solvents were obtained as spontaneous with negative free energy changes <math></math> values, whereas clouding phenomenon was nonspontaneous (<math></math>). For the TX-100 + PMZ system, the enthalpy changes (<math></math> and entropy changes <math></math> values indicated the presence of hydrophobic interaction, dipole–dipole forces and π–π interactions. The compensation parameters (intrinsic enthalpy gain (<math></math>) and compensation temperature (Tc)) were also calculated and explained logically.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Green Synthesis, Characterization, and Biological Evaluation of CuO–ZnO Nanoparticles Using Cyphostemma Setosum Leaf Extract 以茜草叶提取物为原料制备CuO-ZnO纳米颗粒的绿色合成、表征及生物学评价

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-05-29 DOI: 10.1002/slct.202406062

Muthuvel SelvaKumar, Ramaraj Jeyamurugan, Paulraj Adwin Jose, Kanagasabai Muruganandam Ponvel, Mahalingam Sundarajan

{"title":"Green Synthesis, Characterization, and Biological Evaluation of CuO–ZnO Nanoparticles Using Cyphostemma Setosum Leaf Extract","authors":"Muthuvel SelvaKumar, Ramaraj Jeyamurugan, Paulraj Adwin Jose, Kanagasabai Muruganandam Ponvel, Mahalingam Sundarajan","doi":"10.1002/slct.202406062","DOIUrl":"https://doi.org/10.1002/slct.202406062","url":null,"abstract":"The present study details the successful green synthesis, thorough characterization, and extensive biological assessment of CuO–ZnO nanoparticles (NPs) by using aqueous leaf extract of Cyphostemma setosum. UV–vis., spectroscopy identified a distinct absorption peak at 240 nm, indicative of direct band gap transitions, with the optical band gap estimated to be 3.32 eV. FT-IR spectral analysis confirmed the presence of significant functional groups, including hydroxyl (3380 cm⁻¹) and nitrile (2102 cm⁻¹), which suggest effective capping and stabilization of the synthesized NPs. XRD patterns validated the formation of well-crystallized CuO–ZnO phases, a finding further corroborated by SEM and TEM images that revealed a spherical morphology with particle sizes ranging from 20 to 50 nm. The selected area electron diffraction (SAED) pattern indicated a high degree of crystallinity. Antifungal activity of the CuO–ZnO NPs demonstrated significant efficacy, with inhibition zones progressively increasing over time. Antibacterial assays indicated that the synthesized NPs exhibited enhanced activity against both Gram-negative and Gram-positive bacteria, with C. freundii and A. brasilense showing inhibition zones of 22 and 21 mm, respectively. DNA binding studies revealed strong interactions of synthesized CuO—ZnO NPs with DNA, as the binding constant (Kb) of 1.8 × 10⁵ M⁻¹.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 21","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144171578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0