ChemistrySelect最新文献_第2页

Design, Synthesis, Biological Investigations, and in Silico Studies of Sulfonate Esters of 2-(2-benzylidenehydrazono)-4-Oxothiazolidine-5-Acetic Acid as α-Glucosidase Inhibitors

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202500017

Ramandeep Kaur, Rajnish Kumar, Nilambra Dogra, Dr. Asst. Prof. Ashok Kumar Yadav

引用次数: 0

The Electrochemical Luminescence Properties and Applications of Benzofuranone Compounds

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202405954

Yuling Huang, Mengyao Liu, PanPan Xu, Sufan Wang, Yinggui Zhu

{"title":"The Electrochemical Luminescence Properties and Applications of Benzofuranone Compounds","authors":"Yuling Huang, Mengyao Liu, PanPan Xu, Sufan Wang, Yinggui Zhu","doi":"10.1002/slct.202405954","DOIUrl":"https://doi.org/10.1002/slct.202405954","url":null,"abstract":"In this work, we selected two benzofuranone derivatives, phthalide (PA) and coumaranone (Cmno), as the luminophores for electrochemiluminescence (ECL). During the experiments, we employed K₂S₂O₈ as the co-reactant and observed that both compounds could generate ECL signals in K₂S₂O₈ solution. By analyzing their cyclic voltammetry curves, fluorescence spectra, and ECL spectra, among others, we speculated on the ECL mechanisms of these two systems. To further compare the differences in ECL signals between the two systems, we employed density functional theory (DFT) to calculate their molecular orbital energy levels. The results indicated that Cmno is more likely to form an excited state, producing a stronger ECL signal. This theoretical result is consistent with the results obtained from the ECL intensity–potential curves. Additionally, we discovered that 2-dimethylaminoethanol (DMAEA) significantly quenches the ECL signal of Cmno, and this quenching depended on the concentration of DMAEA. Based on these findings, we developed a simple, sensitive, and highly selective method for detecting the concentration of DMAEA.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Facile Synthesis of Ni-BDC/LDH Heterostructured Catalysts With Enhanced Catalytic Activity for Oxygen Evolution Reaction

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202404610

Desheng Li, Xingyu Guo, Zhengrong Xu, Qing Chen, Rui Liu, Congling Li

引用次数: 0

Sustainable Stabilization of Bimetallic MOF via Bamboo-Derived Activated Carbon for Supercapacitor Applications

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202405220

Sindhu Ramachandran, Anit Joseph, Tiju Thomas

{"title":"Sustainable Stabilization of Bimetallic MOF via Bamboo-Derived Activated Carbon for Supercapacitor Applications","authors":"Sindhu Ramachandran, Anit Joseph, Tiju Thomas","doi":"10.1002/slct.202405220","DOIUrl":"https://doi.org/10.1002/slct.202405220","url":null,"abstract":"Metal-organic frameworks (MOFs) are frequently employed as electrode materials for supercapacitors due to their high specific surface area and tunable pore structures. However, this class of materials suffers from low conductivity and cyclic stability, which deteriorates their capacitive performance. Herein, we made a simple hydrothermal synthesis approach to prepare a bimetallic MOF and activated carbon (AC) composite. The easy availability, extremely cheap, and porous bamboo structure makes it suitable for AC production. It exhibits a distinct structure, where the NiCo-MOF nano flakes are outspreaded on the ACs’ surface. Compared with the pristine NiCo-MOF, the composite has enhanced electrochemical performance. The specific capacitance of NiCo-MOF and NiCo-MOF/AC in three electrode measurements are 420 F g−1 and 685 F g−1. It exhibits a 63% improvement in particular capacitance. The rate capability of composite electrodes is about 60% when the current density at 12 A g−1. Also, it exhibits good cyclic stability of about 91% after 1000 cycles at 5 A g−1. This study shows that soft, chemically synthesized, bimetallic MOF/bamboo-derived AC can be a promising electrode material for SC applications.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Folic Acid Conjugated Chitosan Coated Zeolite Imidazole Framework-8 (ZIF-8): A pH-Responsive Drug Delivery System for the Sustained and Targeted Delivery of Curcumin

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202500670

A. S. Akshaya, Jiju KR, R Reshma

{"title":"Folic Acid Conjugated Chitosan Coated Zeolite Imidazole Framework-8 (ZIF-8): A pH-Responsive Drug Delivery System for the Sustained and Targeted Delivery of Curcumin","authors":"A. S. Akshaya, Jiju KR, R Reshma","doi":"10.1002/slct.202500670","DOIUrl":"https://doi.org/10.1002/slct.202500670","url":null,"abstract":"This study explores the development of a pH-responsive drug delivery system using folic acid (FA) conjugated chitosan (CS) coated curcumin (Curn) encapsulated in zeolitic imidazolate framework-8 (ZIF-8) for targeted cancer therapy. The synthesis of FA@CS-coated Curn@ZIF-8 was done through a series of chemical reactions, and the resulting nanocarrier was characterized using UV–vis spectroscopy, FT-IR, PXRD, SEM, and N2 adsorption–desorption isotherms. The UV–vis and FT-IR analyses confirmed the effective encapsulation of Curn in the ZIF-8 framework, while SEM and N2 adsorption studies revealed changes in morphology and porosity. In vitro drug release studies demonstrated that the FA@CS coating significantly enhanced controlled drug release under acidic conditions, mimicking the tumor microenvironment. The MTT assay and microscopic observations indicated a substantial reduction in MCF-7 cell viability, showing the system's potent anticancer efficacy. This pH-responsive drug delivery platform offers promising advancements in targeted therapy, with potential benefits for minimizing off-target effects and improving treatment outcomes in cancer therapy.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Study of Ag/MO2 (M═Ce, Zr, Sn, and Ti) Nanomaterials Synthesized via Surfactant-Free One-Pot Hydrothermal Method for CO Oxidation

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202404592

Vishal B. Upare, Dr. Anjana P Anantharaman

{"title":"Study of Ag/MO2 (M═Ce, Zr, Sn, and Ti) Nanomaterials Synthesized via Surfactant-Free One-Pot Hydrothermal Method for CO Oxidation","authors":"Vishal B. Upare, Dr. Anjana P Anantharaman","doi":"10.1002/slct.202404592","DOIUrl":"https://doi.org/10.1002/slct.202404592","url":null,"abstract":"In this study, Ag/MO2 (M═Ce, Zr, Sn, and Ti) nanomaterials were synthesized via a surfactant-free one-step hydrothermal process followed by calcination at 500 °C for 5 h and investigated the impact of different metal oxides on Ag-based nanomaterials as catalysts for CO oxidation. Comprehensive characterization analysis using various techniques including XRD, BET, FE-SEM with EDS and elemental mapping, TEM, HR-TEM with SAED and XPS, provided insights into the physicochemical properties of the Ag/MO2 nanomaterials. Depending on the variation in the redox (Ag/CeO2 and Ag/TiO2) and nonredox (Ag/ZrO2 and Ag/SnO2) nature of metal oxides, Ag metallic state, crystallite sizes, surface area, morphology, and adsorbed surface oxygen are affected. The catalytic activity towards the CO oxidation was in the order: Ag/CeO2> Ag/ZrO2> Ag/TiO2>> Ag/SnO2. This enhanced performance can be attributed to the presence of metallic Ag, abundant surface oxygen (46.46%), improved interaction between metallic Ag and CeO2 due to rice-ball structure. Ag/CeO2 exhibited better catalytic activity even after 3 consecutive cycles toward CO oxidation (T50% = 150 °C). This resilience can be linked to the stable spherical morphology and intact rice-ball structure. The findings demonstrate the impact of metal oxides on Ag-based nanomaterials physicochemical properties and thus CO oxidation activity.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A Novel UIO-66/Pebax® 1657 Mixed Matrix Membrane Exhibiting Superior CO2 Separation Performance via Nonthermal Air Plasma Modification

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-13 DOI: 10.1002/slct.202405440

Chenxiao Pei, Nan Wang, Yuqi Zhang, Yuhang Zhong, Xingang Liu, Jianyuan Hou, Yuan Yuan, Renxi Zhang

{"title":"A Novel UIO-66/Pebax® 1657 Mixed Matrix Membrane Exhibiting Superior CO2 Separation Performance via Nonthermal Air Plasma Modification","authors":"Chenxiao Pei, Nan Wang, Yuqi Zhang, Yuhang Zhong, Xingang Liu, Jianyuan Hou, Yuan Yuan, Renxi Zhang","doi":"10.1002/slct.202405440","DOIUrl":"https://doi.org/10.1002/slct.202405440","url":null,"abstract":"This paper synthesized a new mixed matrix membrane for CO2 separation. First, the metal-organic framework UIO-66 was treated with air plasma for modification and then embedded in Pebax® 1657. The 10% UIO-66/Pebax® 1657 mixed matrix membranes treated with air plasma significantly improved interfacial compatibility and CO2 adsorption capacity, showing excellent performance. Its permeability reached 453 Barrer as CO2 and the selectivity was 37.8 as CO2/N2. It was confirmed by characterization techniques such as FTIR, XRD, XPS, TGA, NMR, and SEM that the plasma successfully introduced ─NH2 groups and active sites on the UIO-66 surface, thereby significantly improving the interfacial compatibility and adsorption characteristics of the mixed matrix membrane. In this study, the high-performance CO2 separation membrane aP-UIO-66/Pebax was innovatively enhanced through the synergistic effects of graft modification and defect engineering on UIO-66 using nonthermal plasma technology. This approach offers a novel strategy for membrane performance optimization.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Efficient Measurement and Validation of Nitrite with 5% Nafion-Coated with Low-Dimensional Fe2O3 Nanoparticle by Linear Sweep Voltammetry Approach

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-12 DOI: 10.1002/slct.202405896

Fawziah A. Al-Rasheedi, Hadi M. Marwani, Mohammed M. Rahman

{"title":"Efficient Measurement and Validation of Nitrite with 5% Nafion-Coated with Low-Dimensional Fe2O3 Nanoparticle by Linear Sweep Voltammetry Approach","authors":"Fawziah A. Al-Rasheedi, Hadi M. Marwani, Mohammed M. Rahman","doi":"10.1002/slct.202405896","DOIUrl":"https://doi.org/10.1002/slct.202405896","url":null,"abstract":"In this approach, low-dimensional Fe₂O₃ nanoparticles (NPs) synthesized using wet-chemical methods in an alkaline medium were comprehensively characterized using Fourier transform infrared spectroscopy (FTIR), field-emission scanning electron microscopy (FESEM), cyclic voltammetry (CV), X-ray photoelectron spectroscopy (XPS), transmission electron microscopy (TEM), and X-ray diffraction (XRD) before their application in nitrite sensing. These analyses detailed the nanoparticles morphology, optical properties, crystallinity, elemental composition, and electro-catalytic behavior. Fabricated with a 5% Nafion coating on a glassy carbon electrode (GCE), the Fe₂O₃ NPs facilitated efficient electrochemical oxidation of nitrite through two-electron transfer, enabling precise detection. The sensor demonstrated high sensitivity of 1.66 µAmM−1cm−2, reproducibility, and reliability, surpassing conventional detection methods. Nitrite concentration detection with a wide linear dynamic range (LDR) from 2.4 to 13.4 mM, displayed a clear linear current response with increasing applied potential. The sensor also exhibited a low limit of detection (LOD) of 8.6 × 10−6 M, limit of quantification (LOQ) of 26.1 × 10−6 M, enhanced sensitivity, selectivity, and stability, with consistent performance in repeated tests over 50 cycles using LSV. This work introduces an effective approach for nitrite detection using low-dimensional Fe₂O₃ nanostructures, validated through real environmental samples with RSD between 0.415% and 0.866%, whereas recoveries were recorded between 98% and 99.38%, providing a robust and sustainable solution for environmental monitoring.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602514","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemoenzymatic Synthesis of tert-Butyl ((3R, 6R)-6-methyl-piperidin-3-yl)carbamate: A Key Intermediate in Orexin Receptor Antagonist and IRAK4 Inhibitor

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-12 DOI: 10.1002/slct.202405709

Zhe Zhang, Ying-Cong Liang, Tong Li, Chao-Lin Liu, Yun-Hu Zhao, Shan Li, Bing Gu, Lei Zhang

{"title":"Chemoenzymatic Synthesis of tert-Butyl ((3R, 6R)-6-methyl-piperidin-3-yl)carbamate: A Key Intermediate in Orexin Receptor Antagonist and IRAK4 Inhibitor","authors":"Zhe Zhang, Ying-Cong Liang, Tong Li, Chao-Lin Liu, Yun-Hu Zhao, Shan Li, Bing Gu, Lei Zhang","doi":"10.1002/slct.202405709","DOIUrl":"https://doi.org/10.1002/slct.202405709","url":null,"abstract":"tert-Butyl ((3R,6R)-6-methylpiperidin-3-yl)carbamate is a pivotal pharmaceutical intermediate and active pharmacophore in drug synthesis, encompassing applications in orexin receptor antagonist and IRAK4 inhibitor. To date, a simple and efficient synthetic route remains a challenging issue for chemists in constructing chiral centers. In this study, we present a practical process for the preparation of tert-butyl ((3R,6R)-6-methylpiperidin-3-yl)carbamate, the key chiral intermediate via a chemoenzymatic strategy from commercially available ethyl N-Boc-D-pyroglutamate, which undergoes transamination-spontaneous cyclization process by transaminase (ATA) biocatalyst. Our study outlines a shortened-step streamlined procedure circumventing a significant amount of toxic chemicals and hazardous reaction conditions, and features cost-effective and high optical purity with >99.9% enantiomeric excess. The process features great prospect of industrialization application.","PeriodicalId":146,"journal":{"name":"ChemistrySelect","volume":"10 11","pages":""},"PeriodicalIF":1.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143602515","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cover Picture: (ChemistrySelect 11/2025)

IF 1.9 4区化学

ChemistrySelect Pub Date : 2025-03-12 DOI: 10.1002/slct.202581101

引用次数: 0