JACC. Cardiovascular interventions最新文献

{"title":"SESAME to Treat Subaortic Membrane","authors":"Yasemin Ciftcikal BA, Christopher Chieh Yang Koo MD, Adam B. Greenbaum MD, Vasilis C. Babaliaros MD, James M. McCabe MD, G. Burkhard Mackensen MD, PhD, Karim Al-Azizi MD, Rahul Sawhney DO, Robert J. Lederman MD, Omar K. Khalique MD, William Chung MD, Jaffar M. Khan MD, PhD","doi":"10.1016/j.jcin.2025.07.030","DOIUrl":"10.1016/j.jcin.2025.07.030","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 19","pages":"Pages 2427-2429"},"PeriodicalIF":11.4,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S1936-8798(25)02426-4","DOIUrl":"10.1016/S1936-8798(25)02426-4","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 19","pages":"Pages I-CXXXIII"},"PeriodicalIF":11.4,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145278397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular Imaging vs Angiography Guidance for PCI of Severely Calcified Lesions","authors":"Gregg W. Stone MD ,&nbsp;Philippe Genereux MD ,&nbsp;Akiko Maehara MD ,&nbsp;Bruce E. Lewis MD ,&nbsp;Richard A. Shlofmitz MD ,&nbsp;Suhail Dohad MD ,&nbsp;Jithendra Choudary MD ,&nbsp;Thom Dahle MD ,&nbsp;Andres M. Pineda MD ,&nbsp;Kendrick Shunk MD, PhD ,&nbsp;Ehtisham Mahmud MD ,&nbsp;Giora Weisz MD ,&nbsp;Michael B. Collins MD ,&nbsp;Khaldoon Alaswad MD ,&nbsp;Gautam Kumar MD ,&nbsp;Naresh Solankhi MD ,&nbsp;Daniel Dulas MD ,&nbsp;John D. Altman MD ,&nbsp;Carlye Kraemer MS ,&nbsp;Krista M. Stiefel BS ,&nbsp;Ajay J. Kirtane MD, SM","doi":"10.1016/j.jcin.2025.08.024","DOIUrl":"10.1016/j.jcin.2025.08.024","url":null,"abstract":"<div><h3>Background</h3><div>Few studies have examined whether intravascular imaging (IVI) guidance during percutaneous coronary intervention (PCI) of calcified lesions improves clinical outcomes.</div></div><div><h3>Objectives</h3><div>The aim of this study was to determine from a large-scale randomized trial of PCI in severely calcified lesions whether IVI guidance improves event-free survival.</div></div><div><h3>Methods</h3><div>In the ECLIPSE (Evaluation of Treatment Strategies for Severe Calcific Coronary Arteries: Orbital Atherectomy vs. Conventional Angioplasty Technique Prior to Implantation of Drug-Eluting Stents) trial, 2,005 patients with severely calcified lesions were randomized to orbital atherectomy (OA) vs balloon angioplasty (BA) prior to drug-eluting stent placement. IVI with optical coherence tomography or intravascular ultrasound (IVUS) was allowed at operator discretion. The primary clinical outcome was the 1-year rate of target vessel failure (TVF).</div></div><div><h3>Results</h3><div>IVI guidance was used in 1,246 of 2,005 patients (62.1%), including optical coherence tomography in 819 and/or IVUS in 513, while 759 of 2,005 patients (37.9%) underwent PCI with angiographic guidance alone. Median follow-up duration was 365 days (Q1-Q3: 365-365 days). The 1-year Kaplan-Meier estimated rate of TVF was lower among patients with IVI guidance compared with angiographic guidance alone (9.3% vs 13.2%; adjusted HR: 0.74; 95% CI: 0.56-0.97; <em>P</em> = 0.03). The effect of IVI guidance was consistent in patients randomized to OA vs BA (<em>P</em>_interaction = 0.48). The 1-year rate of TVF was 7.7% after optical coherence tomographic guidance compared with 12.2% after IVUS guidance (adjusted HR: 0.78; 95% CI: 0.52-1.18; <em>P</em> = 0.24).</div></div><div><h3>Conclusions</h3><div>IVI guidance during PCI of severely calcified lesions was associated with improved 1-year clinical outcomes compared with angiographic guidance alone, whether OA or BA was used for vessel preparation prior to drug-eluting stent placement. The adjusted difference in 1-year TVF rates were not significantly different with optical coherence tomographic guidance and IVUS guidance.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 19","pages":"Pages 2338-2351"},"PeriodicalIF":11.4,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145278402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TAVR With a Fully Retrievable Device for Pure Aortic Regurgitation After Valve-Sparing Aortic Root Replacement","authors":"Hussam Alsawidi MD ,&nbsp;Zhen-Gang Zhao MD ,&nbsp;Ashraf Haidarah MD,&nbsp;Chen Mao MD, PhD,&nbsp;Feng Yuan MD","doi":"10.1016/j.jcin.2025.06.028","DOIUrl":"10.1016/j.jcin.2025.06.028","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 19","pages":"Pages 2414-2417"},"PeriodicalIF":11.4,"publicationDate":"2025-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144835048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Drug-Coated Balloon Therapy for Chronic Total Coronary Occlusions","authors":"Erion Xhepa MD, PhD,&nbsp;Salvatore Cassese MD, PhD","doi":"10.1016/j.jcin.2025.08.008","DOIUrl":"10.1016/j.jcin.2025.08.008","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 18","pages":"Pages 2222-2225"},"PeriodicalIF":11.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous Coronary Intervention in Multivessel Disease and Infarct-Related Cardiogenic Shock","authors":"Jasmine M. Marquard MD ,&nbsp;Rasmus P. Beske MD, PhD ,&nbsp;Christian Hassager MD, PhD, DMSc ,&nbsp;Lisette O. Jensen MD, PhD, DMSc ,&nbsp;Hans Eiskjær MD, PhD, DMSc ,&nbsp;Norman Mangner MD ,&nbsp;Amin Polzin MD ,&nbsp;Christian Schulze MD ,&nbsp;Carsten Skurk MD ,&nbsp;Peter Nordbeck MD ,&nbsp;Vasileios Panoulas MD ,&nbsp;Sebastian Zimmer MD ,&nbsp;Andreas Schäfer MD ,&nbsp;Nikos Werner MD ,&nbsp;Lene Holmvang MD, PhD, DMSc ,&nbsp;Jacob T. Lønborg MD, PhD, DMSc ,&nbsp;Nanna L.J. Udesen MD, PhD ,&nbsp;Henrik Schmidt MD, PhD, DMSc ,&nbsp;Anders Junker MD, PhD ,&nbsp;Christian J. Terkelsen MD, PhD, DMSc ,&nbsp;Professor Nicos Werner","doi":"10.1016/j.jcin.2025.07.035","DOIUrl":"10.1016/j.jcin.2025.07.035","url":null,"abstract":"<div><h3>Background</h3><div>The optimal percutaneous coronary intervention (PCI) strategy in ST-segment elevation myocardial infarction (STEMI)–related cardiogenic shock and multivessel disease remains uncertain.</div></div><div><h3>Objectives</h3><div>The aim of this study was to investigate the association between PCI strategy and outcomes in STEMI-related cardiogenic shock and multivessel disease.</div></div><div><h3>Methods</h3><div>This exploratory substudy of the DanGer Shock (Danish-German Cardiogenic Shock) multicenter trial included patients with STEMI-related cardiogenic shock and multivessel disease, excluding comatose patients resuscitated from cardiac arrest. Multivessel disease was defined by ≥1 nonculprit angiographic stenosis ≥70%. Patients with an isolated left main culprit were excluded. The planned PCI strategy was registered before randomization. All analyses were performed according to as-treated PCI strategy (immediate multivessel PCI or culprit-only PCI). The primary outcome was all-cause mortality within 180 days; secondary outcomes included renal replacement therapy and acute kidney injury.</div></div><div><h3>Results</h3><div>Of 355 patients included in the DanGer Shock trial, 221 (72%) had multivessel disease; of these, 118 (53%) were treated with culprit-only PCI and 103 (47%) with immediate multivessel PCI. The median pre-PCI SYNTAX (Synergy Between PCI With Taxus and Cardiac Surgery) scores were 28 (Q1-Q3: 22-32) and 29 (Q1-Q3: 22-34), respectively. Chronic total occlusion PCI was performed in 6 of 103 patients (6%) treated with immediate multivessel PCI. All-cause mortality was 72 (61%; 95% CI: 52%-70%) in the culprit-only group and 52 (50%; 95% CI: 41%-60%) in the immediate multivessel PCI group (adjusted OR: 0.40; 95% CI: 0.19-0.83) over a median follow-up period of 45 days (Q1-Q3: 2-180 days). Immediate multivessel PCI was not associated with the secondary outcomes. There was no interaction according to randomization allocation and PCI strategy (<em>P</em> = 1.00).</div></div><div><h3>Conclusions</h3><div>Immediate multivessel PCI was associated with 60% lower odds of all-cause mortality compared with culprit-only PCI.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 18","pages":"Pages 2226-2237"},"PeriodicalIF":11.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical and Transcatheter Mitral Valve Interventions in Older Adults","authors":"Wayne B. Batchelor MD, MHS, MBA ,&nbsp;Samir Kapadia MD, MBA ,&nbsp;Abdulla A. Damluji MD, PhD, MBA","doi":"10.1016/j.jcin.2025.08.017","DOIUrl":"10.1016/j.jcin.2025.08.017","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 18","pages":"Pages 2253-2255"},"PeriodicalIF":11.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145109237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Simplified and Improved Commissural Alignment Technique With the Supra-Annular, Self-Expanding Evolut FX System","authors":"Chieh Yang Christopher Koo MBBS,&nbsp;George Petrossian MD,&nbsp;Newell Robinson MD,&nbsp;William Chung MD,&nbsp;Matthew Henry MD,&nbsp;Andrew Berke MD,&nbsp;Kristin Pasquarello PA,&nbsp;Ziad Ali MD,&nbsp;Omar Khalique MD,&nbsp;Jaffar M. Khan MD","doi":"10.1016/j.jcin.2025.06.003","DOIUrl":"10.1016/j.jcin.2025.06.003","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 18","pages":"Pages 2306-2308"},"PeriodicalIF":11.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144478814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Custom Fluoroscopic Hat-Marker Orientation to Optimize Commissural Alignment in the Evolut Valve","authors":"Osama Elkhateeb MD,&nbsp;Jeremy Wood MD,&nbsp;Christine Herman MD,&nbsp;Hussein Beydoun MD","doi":"10.1016/j.jcin.2025.06.025","DOIUrl":"10.1016/j.jcin.2025.06.025","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 18","pages":"Pages 2303-2305"},"PeriodicalIF":11.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799115","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of Intravascular Ultrasound–Defined Optimal Stent Expansion Criteria for Favorable 1-Year Clinical Outcomes","authors":"Sang-Hyup Lee MD ,&nbsp;Xiaoping Jin MD ,&nbsp;Yong-Joon Lee MD ,&nbsp;Jing Kan MD ,&nbsp;Zhen Ge MD ,&nbsp;Seung-Jun Lee MD ,&nbsp;Sung-Jin Hong MD ,&nbsp;Chul-Min Ahn MD ,&nbsp;Jung-Sun Kim MD ,&nbsp;Byeong-Keuk Kim MD ,&nbsp;Young-Guk Ko MD ,&nbsp;Donghoon Choi MD ,&nbsp;Yangsoo Jang MD ,&nbsp;Gregg W. Stone MD ,&nbsp;Gary S. Mintz MD ,&nbsp;Shao-Liang Chen MD ,&nbsp;Myeong-Ki Hong MD","doi":"10.1016/j.jcin.2025.07.024","DOIUrl":"10.1016/j.jcin.2025.07.024","url":null,"abstract":"<div><h3>Background</h3><div>Robust evidence on optimal stent expansion using intravascular ultrasound (IVUS) is still lacking.</div></div><div><h3>Objectives</h3><div>The aim of this study was to validate the impact of different criteria for IVUS-defined optimal stent expansion on 1-year clinical outcomes after percutaneous coronary intervention (PCI).</div></div><div><h3>Methods</h3><div>Individual patient data from 3 randomized trials were aggregated for this analysis. Patients (n = 6,290) were classified into 3 groups: optimized PCI by IVUS, nonoptimized PCI by IVUS, and angiography-guided PCI. The primary endpoint was target vessel failure (TVF) at 1 year, a composite of cardiac death, target vessel myocardial infarction, or target vessel revascularization.</div></div><div><h3>Results</h3><div>Angiography-guided PCI was performed in 3,208 patients. Optimal stent expansion was evaluated in 3,082 patients with IVUS-guided PCI. For the absolute criterion of minimal stent area (MSA) &gt;5.5 mm² indicating optimal stent expansion, the optimized PCI group had a lower incidence of TVF (1.45% vs 3.86% vs 5.07%) compared with the nonoptimized PCI group (adjusted HR: 0.45; 95% CI: 0.26-0.75; <em>P</em> = 0.002) and the angiography-guided PCI group (adjusted HR: 0.35; 95% CI: 0.22-0.54; <em>P</em> &lt; 0.001). Relative criteria did not show a significantly different TVF incidence between the optimized and nonoptimized PCI groups. In particular, the absolute criterion of MSA &gt;5.5 mm² was associated with a significant reduction of the composite of cardiac death or target vessel myocardial infarction (0.54% in the optimized PCI group vs 1.59% in the nonoptimized PCI group; adjusted HR: 0.39; 95% CI: 0.17-0.91; <em>P</em> = 0.028).</div></div><div><h3>Conclusions</h3><div>Post-PCI stent expansion meeting an absolute criterion of MSA &gt;5.5 mm² was associated with the most favorable clinical outcomes. (Effect of Intravascular Ultrasound in Patients Receiving Percutaneous Coronary Intervention With New-Generation Drug-Eluting Stents: An Individual Patient Data Meta-Analysis of IVUS-XPL, ULTIMATE and IVUS-ACS Randomized Trials; <span><span>CRD42024559794</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 18","pages":"Pages 2197-2205"},"PeriodicalIF":11.4,"publicationDate":"2025-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145108657","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}