JACC. Cardiovascular interventions最新文献

{"title":"Rescue TAVR After Ozaki Procedure","authors":"Mateusz Orzalkiewicz MD, PhD, Gabriele Ghetti MD, Giulio Bruno Antonio MD, PhD, Nevio Taglieri MD, PhD, Gabriele Egidy Assenza MD, Lucio Careddu MD, PhD, AgulliMarta Agulli MD, Sara Schirru MD, Andrea Donti MD, Angeli Emanuela MD, PhD, Saia Francesco MD, PhD, Palmerini Tullio MD","doi":"10.1016/j.jcin.2026.07.041","DOIUrl":"10.1016/j.jcin.2026.07.041","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2667-2669"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immediate Versus Staged Complete Revascularization in Multivessel Disease and STEMI","authors":"Daniel O'Callaghan MB, MCh,&nbsp;Himanshu Rai PhD,&nbsp;Daniele Giacoppo MD, MSc, PhD,&nbsp;J.J. Coughlan MB, BCh, MD,&nbsp;Róisín Colleran MB, BCh, PhD,&nbsp;Rory Durand MB, BCh,&nbsp;Mark S. Spence MB, BCh, MD,&nbsp;Mark Kennedy MB, BCh, MD,&nbsp;Gavin J. Blake MB, BCh, MD,&nbsp;Colm G. Hanratty MB, BCh, MD,&nbsp;Adnan Kastrati MD,&nbsp;Robert A. Byrne MB, BCh, PhD","doi":"10.1016/j.jcin.2026.07.033","DOIUrl":"10.1016/j.jcin.2026.07.033","url":null,"abstract":"<div><h3>Background</h3><div>For patients with ST-segment elevation myocardial infarction (STEMI) and multivessel disease, complete revascularization is recommended. The timing of nonculprit lesion intervention, either immediately during the index procedure or staged at a later time, has been investigated in randomized controlled trials (RCTs).</div></div><div><h3>Objectives</h3><div>This study sought to perform a meta-analysis of RCTs comparing immediate vs staged complete revascularization in patients with multivessel disease presenting with STEMI.</div></div><div><h3>Methods</h3><div>We conducted a frequentist, pairwise meta-analysis. Studies were selected based on the following inclusion criteria: multicenter RCTs comparing immediate vs staged nonculprit revascularization in patients presenting with STEMI; exclusive use of second-generation (or newer) drug-eluting stents; a follow-up duration of ≥1 year; and publication in a peer-reviewed journal. The primary outcome of interest was all-cause mortality, whereas secondary outcomes included myocardial infarction (MI), cardiac death, and unplanned revascularization. Summary estimates were computed using random-effects models with inverse-variance weighting based on trial-level HRs and 95% CIs. The study protocol was registered on PROSPERO (CRD420251124207).</div></div><div><h3>Results</h3><div>After a systematic search, 4 randomized trials comprising 2,651 patients were included in the meta-analysis. The risk of all-cause death at 1-year was higher with immediate complete revascularization (HR: 1.50; 95% CI: 1.02-2.21; <em>P</em> = 0.04; prediction interval [PI]: 0.80-2.81; <em>I</em>^<em>2</em> = 0%; <em>t</em>^<em>2</em> = 0). Immediate complete revascularization reduced the risk of recurrent MI when using the protocol specified definitions which included procedural MI (HR: 0.58; 95% CI: 0.36-0.94; <em>P</em> = 0.02; PI: 0.22-1.54; <em>I</em>^<em>2</em> = 0%; <em>t</em>^<em>2</em> = 0.034) but did not reduce risk of spontaneous MI (HR: 0.91; 95% CI: 0.55-1.48; <em>P</em> = 0.90; PI: 0.41-2.00; <em>I</em>^<em>2</em> = 0%; τ² = 0.00). The risk of cardiac death and unplanned revascularization was comparable between the treatment groups.</div></div><div><h3>Conclusions</h3><div>In STEMI and multivessel disease, immediate complete revascularization may be associated with an increased risk of all-cause death at 1-year when compared with staged complete revascularization. The treatment effect on mortality should be interpreted cautiously because of the relatively low number of deaths across the 4 trials and the statistical fragility of the findings. The findings from this analysis do not support an immediate complete revascularization strategy in these patients.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2589-2600"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Conduction System Versus Right Ventricular Pacing in Patients Undergoing TAVR","authors":"Felipe Diez-Delhoyo MD,&nbsp;Jorge Sanz-Sanchez MD, PhD,&nbsp;Guillem Muntane-Carol MD,&nbsp;Ignacio Jesus Amat-Santos MD, PhD,&nbsp;Juan Francisco Oteo Dominguez MD,&nbsp;Ricardo Rivera-Lopez MD, PhD,&nbsp;Lluis Asmarats MD,&nbsp;Manuel Pan MD, PhD,&nbsp;Jose Maria Novoa Medina MD,&nbsp;Juan Antonio Franco-Pelaez MD,&nbsp;Carlos Cuellas MD,&nbsp;Jessica Roa-Garrido MD,&nbsp;Maria Tamargo MD, PhD,&nbsp;Gabriela Veiga MD,&nbsp;Marta Herrero-Brocal MD,&nbsp;Pablo Miguel Valentin Garcia MD,&nbsp;Juan Garcia-Lara MD,&nbsp;Javier Cuesta MD, PhD,&nbsp;Felix Valencia-Serrano MD,&nbsp;Raquel Pimienta-Gonzalez MD,&nbsp;Fernando Sarnago Cebada MD","doi":"10.1016/j.jcin.2026.08.008","DOIUrl":"10.1016/j.jcin.2026.08.008","url":null,"abstract":"<div><h3>Background</h3><div>Pacemaker implantation after transcatheter aortic valve replacement (TAVR) is common and has been associated with adverse clinical outcomes. Cardiac physiological pacing (CPP) may preserve ventricular synchrony and reduce heart failure (HF) events compared with right ventricular pacing (RVP).</div></div><div><h3>Objectives</h3><div>This study sought to compare long-term clinical outcomes of CPP vs RVP in patients requiring permanent pacing after TAVR.</div></div><div><h3>Methods</h3><div>Registro de Estimulación Fisiológica-TAVR is a retrospective, multicenter nationwide registry including patients undergoing TAVR and pacemaker implantation within 30 days. Propensity score matching (1:1) was performed using baseline clinical and echocardiographic variables, yielding 466 matched pairs. The primary endpoint was the composite of cardiovascular death or HF hospitalization. Cox proportional hazards models were used for time-to-event analyses. Median follow-up was 24 months.</div></div><div><h3>Results</h3><div>In the propensity score–matched cohort, CPP was associated with a lower incidence of the primary endpoint than RVP (9.7% vs 17.6%; HR: 0.57; 95% CI: 0.39-0.83; <em>P</em> = 0.003). This difference was driven by fewer HF hospitalizations (7.9% vs 13.9%; HR: 0.57; 95% CI: 0.37-0.86; <em>P</em> = 0.008). No significant differences were observed in cardiovascular death or all-cause mortality between groups.</div></div><div><h3>Conclusions</h3><div>In this multicenter propensity score–matched study, CPP after TAVR was associated with a lower risk of the primary endpoint, driven by fewer HF hospitalizations. These findings support the need for further randomized clinical trials to evaluate the role of CPP in post-TAVR patients requiring ventricular pacing.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2635-2647"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First Report of Wire-Anchored BA-BASILICA Enabling TAVR in Type-0 Bicuspid Aortic Stenosis Complicated by Cardiogenic Shock","authors":"Leo Kar Lok Lai MBChB,&nbsp;Geri L.N. Wong MBChB,&nbsp;Kevin K.H. Kam MBChB,&nbsp;Vyanne Hei-Tung Chan MBBS,&nbsp;Fuk Kei Fong MBBS,&nbsp;Zoe Hei Yu Chu MBChB,&nbsp;Kent C.Y. So MBChB","doi":"10.1016/j.jcin.2026.08.012","DOIUrl":"10.1016/j.jcin.2026.08.012","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2664-2666"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CAD Complexity in TAVR Patients","authors":"Giulio Stefanini MD, PhD, MSc,&nbsp;Alessandro Gabrielli MD,&nbsp;Francesco Tartaglia MD","doi":"10.1016/j.jcin.2026.08.011","DOIUrl":"10.1016/j.jcin.2026.08.011","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2631-2634"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149164317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Novel Iatrogenic Atrial Septal Defect Closure Method for Peri-Cannular Left-Atrial Thrombosis During LAVA-ECMO Explant","authors":"Syed H. Haq DO,&nbsp;Amanda Laird CNP,&nbsp;Emily Shappell CCP,&nbsp;Andrew H. Macke RT(R)CI,&nbsp;Sandeep M. Patel MD","doi":"10.1016/j.jcin.2026.07.019","DOIUrl":"10.1016/j.jcin.2026.07.019","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2670-2673"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Particles of Drug-Coated Balloons Captured by Flow Reversal Method","authors":"Daichi Yoshii MD,&nbsp;Osamu Iida MD, PhD,&nbsp;Masahiko Fujihara MD,&nbsp;Takuya Tsujimura MD,&nbsp;Taku Toyoshima MD,&nbsp;Yoshiteru Okina MD,&nbsp;Hitoshi Minamiguchi MD,&nbsp;Yasuhiro Ichibori MD,&nbsp;Kei Nakamoto MD,&nbsp;Naoki Mori MD","doi":"10.1016/j.jcin.2026.07.040","DOIUrl":"10.1016/j.jcin.2026.07.040","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2660-2663"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraprocedural Cardiac Arrest in Patients Undergoing Percutaneous Coronary Interventions in the United States","authors":"Ramya C. Mosarla MD,&nbsp;Binita Shah MD, MS,&nbsp;Sunil V. Rao MD,&nbsp;Sripal Bangalore MD, MHA,&nbsp;Pratik Manandhar PhD,&nbsp;Leo Brothers PhD,&nbsp;Jennifer Rymer MD,&nbsp;Nathaniel R. Smilowitz MD, MS","doi":"10.1016/j.jcin.2026.07.035","DOIUrl":"10.1016/j.jcin.2026.07.035","url":null,"abstract":"<div><h3>Background</h3><div>Cardiac arrest (CA) during percutaneous coronary interventions (PCI) is a catastrophic procedural complication. Contemporary rates of CA during PCI are unknown.</div></div><div><h3>Objectives</h3><div>This study sought to understand contemporary rates of CA, associated mortality, and identify predictors of CA during PCI.</div></div><div><h3>Methods</h3><div>Patients with CA during PCI from 2018 to 2023 were identified from the National Cardiovascular Data Registry CathPCI Registry. Trends in intraprocedural CA (IPCA) incidence and in-hospital death were evaluated. Predictors of IPCA and risk-adjusted mortality were identified.</div></div><div><h3>Results</h3><div>A total of 36,755 IPCA occurred during 3,956,840 PCIs (0.93%), including in 0.24% of elective PCIs, 0.32% of PCIs for stable coronary artery disease, and 1.28% of acute coronary syndrome interventions. The incidence of IPCA increased over time (0.62% in 2018 to 1.07% in 2023; <em>P</em> &lt; 0.0001). In-hospital death occurred in 40.5% of patients with IPCA, 45.4% of whom died in the cardiac catheterization laboratory. Notably, although risk-adjusted IPCA increased (0.79% to 0.95%; <em>P</em> = 0.042), slight declines in risk-adjusted mortality (45.1% to 43.6%; <em>P</em> = 0.027) were observed over time. PCI for ST-segment elevation myocardial infarction, non–ST-segment acute coronary syndromes, increasing age, ventricular arrhythmias, severe aortic stenosis, vasopressors or inotrope use, mechanical circulatory support, coronary perforation, coronary dissection, cardiac tamponade, intraprocedural heart failure or myocardial infarction, and temporary cardiac pacemaker implantation were associated with increased adjusted odds of IPCA.</div></div><div><h3>Conclusions</h3><div>IPCA complicates 0.93% of contemporary PCI. Despite an increasing incidence of risk-adjusted IPCA, there were slight declines in risk-adjusted in-hospital mortality in the study period. Several patient and procedural characteristics were independently associated with intraprocedural CA.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2604-2615"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149169485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intraprocedural Cardiac Arrest","authors":"Sundeep Shenoy MD, MBA,&nbsp;Kapil Lotun MD","doi":"10.1016/j.jcin.2026.09.002","DOIUrl":"10.1016/j.jcin.2026.09.002","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2616-2618"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149172259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S1936-8798(26)02525-2","DOIUrl":"10.1016/S1936-8798(26)02525-2","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages I-CXLIII"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149174439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}