Cheuk Bong Ho MBBS, Jake Yin Kei Yeung MBChB, Michael Chi Shing Chiang MBBS, Esmond Yan Hang Fong MBBS, Shing Fung Chui MBChB, Alan Ka Chun Chan MBBS, Eric Chi Yuen Wong MBBS, Michael Kang Yin Lee MBBS
{"title":"Double Kissing Shockwave Lithotripsy in Calcified Aortic Coarctation","authors":"Cheuk Bong Ho MBBS, Jake Yin Kei Yeung MBChB, Michael Chi Shing Chiang MBBS, Esmond Yan Hang Fong MBBS, Shing Fung Chui MBChB, Alan Ka Chun Chan MBBS, Eric Chi Yuen Wong MBBS, Michael Kang Yin Lee MBBS","doi":"10.1016/j.jcin.2024.11.040","DOIUrl":"10.1016/j.jcin.2024.11.040","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1065-1066"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364648","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Won-Keun Kim MD , Ole de Backer MD , Matthias Renker MD , Efstratios I. Charitos MD, PhD , Chris Frawley BSME , Yusuke Kobari MD , Mohamed Abdel-Wahab MD , Ahmed Abdelhafez MD , Niklas Lankisch MD , Darren Mylotte MD , Osama Soliman MD, PhD , Michael Joner MD , Helge Möllmann MD , Yeong-Hoon Choi MD , Samuel Sossalla MD
{"title":"Clinical Impact of Midframe Underexpansion Following TAVR Using a Self-Expanding Transcatheter Heart Valve","authors":"Won-Keun Kim MD , Ole de Backer MD , Matthias Renker MD , Efstratios I. Charitos MD, PhD , Chris Frawley BSME , Yusuke Kobari MD , Mohamed Abdel-Wahab MD , Ahmed Abdelhafez MD , Niklas Lankisch MD , Darren Mylotte MD , Osama Soliman MD, PhD , Michael Joner MD , Helge Möllmann MD , Yeong-Hoon Choi MD , Samuel Sossalla MD","doi":"10.1016/j.jcin.2025.02.013","DOIUrl":"10.1016/j.jcin.2025.02.013","url":null,"abstract":"<div><h3>Background</h3><div>The occurrence and clinical impact of transcatheter heart valve midframe underexpansion following transcatheter aortic valve replacement are not well understood.</div></div><div><h3>Objectives</h3><div>The aim of this study was to evaluate midframe underexpansion among patients treated with the self-expanding ACURATE neo2 device.</div></div><div><h3>Methods</h3><div>This retrospective analysis included 604 patients (median age 82 years; Q1-Q3: 78-85 years; 61.4% women) from 2 European high-volume centers. Midframe underexpansion was assessed on postimplantation fluoroscopic images and defined as nonparallelism of commissure posts. The primary endpoint was a composite of all-cause mortality, stroke, or rehospitalization at 1 year.</div></div><div><h3>Results</h3><div>Midframe underexpansion was identified in 13.9% of patients (84 of 604) and was associated with higher rates of the primary endpoint (33 of 84 [39.3%; 95% CI: 28.8%-50.5%] vs 54 of 520 [10.4%; 95% CI: 7.9%-13.3%]; <em>P</em> < 0.001) and each of its components. Furthermore, midframe underexpansion was independently associated with 1-year all-cause mortality (adjusted HR: 4.07; 95% CI: 2.26-7.33; <em>P</em> < 0.001). The only independent predictor of midframe underexpansion was the absence of postdilatation (adjusted OR: 5.76; 95% CI: 2.60-12.77; <em>P</em> < 0.001). Postdilatation significantly decreased the rate and extent of midframe underexpansion.</div></div><div><h3>Conclusions</h3><div>In this European cohort of ACURATE neo2 recipients, midframe underexpansion occurred in a minor proportion and was associated with poorer clinical outcomes through 1 year. Postdilatation effectively reduced the rate and extent of midframe underexpansion.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1028-1041"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mark M.P. van den Dorpel MD , Rutger-Jan Nuis MD, PhD , Nic Debusschere PhD , Giorgia Rocatello PhD , Peter Mortier PhD , Nicolas M. Van Mieghem MD, PhD
{"title":"Lifetime Management in Transcatheter Aortic Valve Replacement Through Patient-Specific Simulations","authors":"Mark M.P. van den Dorpel MD , Rutger-Jan Nuis MD, PhD , Nic Debusschere PhD , Giorgia Rocatello PhD , Peter Mortier PhD , Nicolas M. Van Mieghem MD, PhD","doi":"10.1016/j.jcin.2024.11.023","DOIUrl":"10.1016/j.jcin.2024.11.023","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1060-1061"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143023455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Seung Hun Lee MD, PhD , Ye Chan Kim MD , Darae Kim MD, PhD, Jin-Oh Choi MD, PhD, Ki Hong Choi MD, Joo-Yong Hahn MD, PhD, Seung-Hyuk Choi MD, PhD, Sang Eun Yoon MD, PhD, Kihyun Kim MD, PhD, Jung-Sun Kim MD, PhD, Hyeon-Cheol Gwon MD, PhD, Joo Myung Lee MD, MPH, PhD
{"title":"Microvascular Resistance Reserve as a Novel Prognostic Marker in Cardiac Amyloidosis","authors":"Seung Hun Lee MD, PhD , Ye Chan Kim MD , Darae Kim MD, PhD, Jin-Oh Choi MD, PhD, Ki Hong Choi MD, Joo-Yong Hahn MD, PhD, Seung-Hyuk Choi MD, PhD, Sang Eun Yoon MD, PhD, Kihyun Kim MD, PhD, Jung-Sun Kim MD, PhD, Hyeon-Cheol Gwon MD, PhD, Joo Myung Lee MD, MPH, PhD","doi":"10.1016/j.jcin.2025.01.422","DOIUrl":"10.1016/j.jcin.2025.01.422","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1082-1084"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143567169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Smoking Status at Baseline and 10-Year Outcomes After Drug-Eluting Stent Implantation","authors":"Antonia Presch MD , J.J. Coughlan MB, BCh , Sarah Bär MD , Salvatore Brugaletta MD, PhD , Michael Maeng MD, PhD , Sebastian Kufner MD , Luis Ortega-Paz MD, PhD , Lorenz Räber MD, PhD , Karl-Ludwig Laugwitz MD , Lisette Okkels Jensen MD, PhD , Stephan Windecker MD , Kevin Kris Warnakula Olesen MD, PhD , Manel Sabaté MD, PhD , Dik Heg PhD , Adnan Kastrati MD , Salvatore Cassese MD, PhD","doi":"10.1016/j.jcin.2024.12.028","DOIUrl":"10.1016/j.jcin.2024.12.028","url":null,"abstract":"<div><h3>Background</h3><div>Studies investigating 10-year outcomes according to smoking status at baseline in a largescale population undergoing percutaneous coronary intervention (PCI) with drug-eluting stent (DES) implantation are scarce.</div></div><div><h3>Objectives</h3><div>The authors sought to assess the association between smoking status at baseline and 10-year outcomes after PCI with DES implantation.</div></div><div><h3>Methods</h3><div>We pooled individual participant data from 5 randomized trials including patients with 10-year follow-up after DES implantation. We divided participants into 2 groups as per smoking status at baseline. The main outcome was all-cause death. Secondary outcomes included cardiovascular death, myocardial infarction (MI), definite stent thrombosis (ST), and repeat revascularization (of target lesion, target vessel [TVR], or non-target vessel).</div></div><div><h3>Results</h3><div>A total of 9,527 patients undergoing PCI with DES implantation were included in this analysis, (smoking n = 2,365; nonsmoking, n = 7,162). After multivariable adjustment, smoking was associated with a higher risk of all-cause death (HR<sub>adj</sub>: 1.45; 95% CI: 1.33-1.59), cardiovascular death (HR<sub>adj</sub>: 1.59; 95% CI: 1.41-1.80), and definite ST (HR<sub>adj</sub>: 2.09; 95% CI: 1.34-3.26) over 10 years after PCI. The risk of MI was comparable in the first 30 days after PCI, but increased significantly from 1 to 10 years in the smoking group (HR<sub>adj</sub>: 1.60; 95% CI: 1.36-1.90). Smoking was associated with a lower risk of target lesion revascularization and target vessel revascularization, but a comparable risk of non-target vessel revascularization.</div></div><div><h3>Conclusions</h3><div>In patients undergoing PCI with DES, smoking at baseline is associated with an increased risk of death, MI, and ST, but a lower risk of repeat revascularization through to 10 years.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1001-1010"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michele Morosato MD , Carlo Gaspardone MD , Davide Romagnolo MD , Matteo Pagnesi MD , Luca Baldetti MD , Sara Dormio MD , Francesco Federico MD , Anna Mara Scandroglio MD , Alaide Chieffo MD , Cosmo Godino MD , Alberto Margonato MD , Marianna Adamo MD , Marco Metra MD , Didier Tchetche MD , Nicolas Dumonteil MD , Marysia S. Tweet MD, MS , Jacqueline Saw MD , Alessandro Beneduce MD
{"title":"Left Main Spontaneous Coronary Artery Dissection","authors":"Michele Morosato MD , Carlo Gaspardone MD , Davide Romagnolo MD , Matteo Pagnesi MD , Luca Baldetti MD , Sara Dormio MD , Francesco Federico MD , Anna Mara Scandroglio MD , Alaide Chieffo MD , Cosmo Godino MD , Alberto Margonato MD , Marianna Adamo MD , Marco Metra MD , Didier Tchetche MD , Nicolas Dumonteil MD , Marysia S. Tweet MD, MS , Jacqueline Saw MD , Alessandro Beneduce MD","doi":"10.1016/j.jcin.2025.01.427","DOIUrl":"10.1016/j.jcin.2025.01.427","url":null,"abstract":"<div><h3>Background</h3><div>Spontaneous coronary artery dissection (SCAD) is an uncommon cause of acute myocardial infarction (MI) and is associated with substantial adverse events. SCAD involving the left main coronary artery (LM) is a rare but potentially life-threatening condition. Currently, minimal data on LM SCAD have been reported.</div></div><div><h3>Objectives</h3><div>The aim of this study was to investigate clinical features, contemporary management, and clinical outcomes of patients with LM SCAD.</div></div><div><h3>Methods</h3><div>A systematic review and pooled analysis of published case reports was conducted using “left main” and “dissection” as keywords. The authors screened 1,106 papers in MEDLINE and Embase published between 1990 and 2023.</div></div><div><h3>Results</h3><div>The final analysis included 132 patients (mean age 40 ± 11 years, 80% women) diagnosed with LM SCAD. Remarkably, 36% of cases occurred during pregnancy, and 95% presented with acute coronary syndrome, 22% with cardiogenic shock, and 8% with ventricular arrhythmias. At 120-day median follow-up, all-cause death occurred in 9%, left ventricular assist device implantation or heart transplantation in 4%, recurrent MI in 13%, and urgent myocardial revascularization (MR) in 21%. Compared with conservative management, early revascularization by percutaneous coronary intervention or coronary artery bypass grafting significantly reduced the composite endpoint of all-cause death, left ventricular assist device implantation or heart transplantation, recurrent MI, and urgent MR (adjusted HR: 0.37; 95% CI: 0.20-0.69; <em>P</em> < 0.001).</div></div><div><h3>Conclusions</h3><div>LM SCAD carried significant acute morbidity and mortality. Early revascularization (percutaneous coronary intervention or coronary artery bypass graft) was associated with a lower incidence of early adverse outcomes compared with conservative management, driven largely by reduction in recurrent MI and urgent MR. These hypothesis-generating data should be confirmed in future prospective registries and clinical trials.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 975-983"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143881646","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Decade of Follow-Up by the DECADE Cooperation","authors":"Michael A. Kutcher MD","doi":"10.1016/j.jcin.2025.01.449","DOIUrl":"10.1016/j.jcin.2025.01.449","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 8","pages":"Pages 1011-1012"},"PeriodicalIF":11.7,"publicationDate":"2025-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}