JACC. Cardiovascular interventions最新文献

{"title":"Eligibility for Transcatheter Tricuspid Valve Interventions in Patients With Tricuspid Regurgitation.","authors":"Tetsu Tanaka, Johanna Vogelhuber, Can Öztürk, Miriam Silaschi, Farhad Bakhtiary, Sebastian Zimmer, Georg Nickenig, Marcel Weber, Atsushi Sugiura","doi":"10.1016/j.jcin.2024.09.019","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.019","url":null,"abstract":"<p><strong>Background: </strong>It remains unclear what proportion of patients with tricuspid regurgitation (TR) are suitable candidates for transcatheter tricuspid valve intervention (TTVI) in clinical practice.</p><p><strong>Objectives: </strong>The aim of this study was to ascertain the prevalence of eligibility for tricuspid transcatheter edge-to-edge repair (T-TEER) and transcatheter tricuspid valve replacement (TTVR) devices among patients with TR.</p><p><strong>Methods: </strong>The tricuspid valve anatomy of all consecutive patients with TR who were considered for TTVI in local heart team conferences was retrospectively reviewed. According to current expert consensus, the anatomical feasibility for T-TEER was classified into 3 groups: favorable, feasible, and unfavorable anatomy. Clinical and anatomical eligibility for TTVR was evaluated in patients with cardiac computed tomographic (CCT) images.</p><p><strong>Results: </strong>Among 491 patients, 99 (20.2%) and 235 (47.9%) were considered to have favorable and feasible anatomy for T-TEER, respectively. In contrast, 157 patients (32.0%) had unfavorable anatomy for T-TEER. The most common reason for unfavorable anatomy for T-TEER was large coaptation gap width (66.2%), followed by anteroposterior TR jet location (62.4%). Among 327 patients with CCT images, 205 (62.7%) were judged to be clinically or anatomically ineligible for TTVR, mainly because of tricuspid annuli larger than commercially available prosthesis sizes (65.4%). Combined echocardiographic and CCT assessment showed that 23.2% of the patients with TR were ineligible for both T-TEER and TTVR.</p><p><strong>Conclusions: </strong>Of 491 patients requiring TTVI, 32.0% had unfavorable anatomy for T-TEER, and 37.3% of patients with CCT images were eligible for TTVR. Despite the emergence of TTVR devices, 23.2% of patients with TR remained ineligible for both T-TEER and TTVR.</p>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2732-2744"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813237","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVOQUE Transcatheter Tricuspid Valve Replacement: 5 Years On.","authors":"Neil P Fam, Sami Alnasser, Djeven P Deva, Gianluigi Bisleri, Mark D Peterson, Geraldine Ong","doi":"10.1016/j.jcin.2024.09.064","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.064","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2829-2830"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reply: Rethinking Thrombus Aspiration in STEMI: Balancing Efficacy and Risk.","authors":"Ho Sung Jeon, Sung Gyun Ahn","doi":"10.1016/j.jcin.2024.10.047","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.047","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2842"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"1-Year Outcomes of Transcatheter Tricuspid Annuloplasty for Patients With Severe Atrial Functional Tricuspid Regurgitation.","authors":"Xiaochun Zhang, Dawei Lin, Wei Li, Dandan Chen, Haiyan Chen, Xue Yang, Kai Hou, Wenzhi Pan, Daxin Zhou, Junbo Ge","doi":"10.1016/j.jcin.2024.09.076","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.076","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2843-2844"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Atrial Secondary Tricuspid Regurgitation: Insights Into the EuroTR Registry.","authors":"Lukas Stolz, Karl-Patrik Kresoja, Jennifer von Stein, Vera Fortmeier, Benedikt Koell, Wolfgang Rottbauer, Mohammad Kassar, Bjoern Goebel, Paolo Denti, Paul Achouh, Tienush Rassaf, Manuel Barreiro-Perez, Peter Boekstegers, Andreas Rück, Philipp M Doldi, Julia Novotny, Monika Zdanyte, Marianna Adamo, Flavien Vincent, Philipp Schlegel, Ralph Stephan von Bardeleben, Thomas J Stocker, Ludwig T Weckbach, Mirjam G Wild, Christian Besler, Stephanie Brunner, Stefan Toggweiler, Julia Grapsa, Tiffany Patterson, Holger Thiele, Tobias Kister, Giuseppe Tarantini, Giulia Masiero, Marco De Carlo, Alessandro Sticchi, Mathias H Konstandin, Eric Van Belle, Marco Metra, Tobias Geisler, Rodrigo Estévez-Loureiro, Peter Luedike, Nicole Karam, Francesco Maisano, Philipp Lauten, Fabien Praz, Mirjam Kessler, Daniel Kalbacher, Volker Rudolph, Christos Iliadis, Philipp Lurz, Jörg Hausleiter","doi":"10.1016/j.jcin.2024.10.028","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.028","url":null,"abstract":"<p><strong>Background: </strong>Atrial secondary tricuspid regurgitation (A-STR) has been proposed as an important etiologic subentity of secondary tricuspid regurgitation (STR). Patients with A-STR are frequently treated using transcatheter tricuspid valve edge-to-edge repair (T-TEER).</p><p><strong>Objectives: </strong>The aims of this study were to evaluate prevalence and outcomes following T-TEER for severe A-STR and to compare the results to patients with nonatrial STR.</p><p><strong>Methods: </strong>The study included patients from the EuroTR (European Registry of Transcatheter Repair for Tricuspid Regurgitation) registry who underwent T-TEER for STR from 2016 until 2022. A-STR was defined as a ratio of end-systolic right atrial area to right ventricular area ≥1.5 in the presence of preserved right ventricular function (tricuspid annular plane systolic excursion >17 mm). The primary study endpoint was 2-year survival free from heart failure hospitalization. Secondary endpoints were 2-year survival, tricuspid regurgitation (TR) reduction at discharge and 1-year follow-up as well as changes in NYHA functional class.</p><p><strong>Results: </strong>This study included 641 patients (50% women) with a mean age of 79 ± 7 years. The overall prevalence of A-STR was 31% (n = 196). A-STR was associated with a higher prevalence of atrial fibrillation, less frequent comorbidities, better biventricular function, less leaflet tenting, and larger atria. Although TR severity was comparable at baseline, patients with A-STR had more effective procedural TR reduction (TR ≤2+ in 86.9% vs 80.4% of those with nonatrial STR; P = 0.005). Although NYHA functional class improved in both STR subetiologies, the symptomatic burden was lower in patients with A-STR at the latest available follow-up (NYHA functional class ≥III in 46% of patients with nonatrial STR vs 38% in those with A-STR; P = 0.033). Beyond that, A-STR was associated with higher 2-year survival rates free from heart failure hospitalization (66.3% [Q1-Q3: 58.2%-75.5%] vs 47.5% [Q1-Q3: 41.7%-54.7%] in patients with nonatrial STR; P < 0.001). Median survival follow-up was 379 days [Q1-Q3: 155-697 days].</p><p><strong>Conclusions: </strong>A-STR is a common phenotype of STR and is associated with effective TR reduction and symptomatic reduction after T-TEER.</p>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2781-2791"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Repair Solutions: Will They Stand the Test of Time?","authors":"Mirvat Alasnag","doi":"10.1016/j.jcin.2024.10.036","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.036","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2808-2810"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transjugular Transcatheter Tricuspid Valve Replacement With EVOQUE.","authors":"Melissa Y Y Moey, Mathias Claeys, Sami Alnasser, Geraldine Ong, Mark D Peterson, Neil P Fam","doi":"10.1016/j.jcin.2024.09.032","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.032","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2826-2828"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Repair of the Tricuspid Valve: Not Just a Matter of Aesthetics.","authors":"Marco De Carlo, Matteo Mazzola","doi":"10.1016/j.jcin.2024.08.038","DOIUrl":"10.1016/j.jcin.2024.08.038","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":" ","pages":"2778-2780"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620859","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"First-in-Human Experience With 4D Holographic Therapy Guidance in Left Atrial Appendage Occlusion.","authors":"Jacob R Dutcher, Wade T Schmidt, Hardik H Doshi, Benjamin K Johnson, Paul R Sander, Sharath S Subramanian","doi":"10.1016/j.jcin.2024.09.063","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.063","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2848-2849"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Edge-to-Edge Repair in Patients With Complex Tricuspid Valve Anatomy.","authors":"David H Adams, Gilbert H L Tang, Brian K Whisenant, Susheel K Kodali, Gagan D Singh, Neil P Fam, Saibal Kar, Matthew J Price, Christian Spies, Jonathan G Schwartz, Raj R Makkar, Peter Tadros, Anita W Asgar, Ulrich P Jorde, Raymond L Benza, Vinod H Thourani, Patrick M McCarthy, Richard Bae, Thomas W R Smith, D Scott Lim, Moody M Makar, Hursh Naik, M Azeem Latib, Marta Sitges, Ralph Stephan von Bardeleben, Philipp Lurz, Nadira Hamid, Rebecca T Hahn, Paul Sorajja","doi":"10.1016/j.jcin.2024.08.035","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.08.035","url":null,"abstract":"<p><strong>Background: </strong>Untreated severe tricuspid regurgitation (TR) carries a poor prognosis.</p><p><strong>Objectives: </strong>The authors report the 1-year outcomes of transcatheter edge-to-edge repair (TEER) with the TriClip system (Abbott Structural Heart) in patients with complex tricuspid valve anatomies.</p><p><strong>Methods: </strong>The multicenter, international TRILUMINATE Pivotal (Trial to Evaluate Cardiovascular Outcomes in Patients Treated with the Tricuspid Valve Repair System Pivotal) trial included a single-arm cohort, with complex tricuspid valve anatomies excluded from the randomized arm (ie, anticipated TR reduction but not to moderate or less after TEER). The primary outcome endpoint of the single arm was 1-year survival with a Kansas City Cardiomyopathy Questionnaire score improvement ≥10 points.</p><p><strong>Results: </strong>In the primary analysis population (N = 100), the mean age was 80 ± 6 years, and 35% had a cardiac implantable electronic device lead. Nearly 90% of patients had massive or torrential TR, 44% had prior left-sided valve interventions, 63% had ≥4-segmental tricuspid leaflet morphology, and the coaptation gap averaged 7.4 ± 2.7 mm. The primary endpoint was met (outcome: 46.2%, performance goal: 30%; P = 0.0008). A total of 81% of subjects had moderate or less TR at 1 year. No major adverse events or deaths occurred within 30 days postprocedure. One-year all-cause mortality and heart failure hospitalization were 15% and 24%, respectively. Significant improvements in NYHA functional class and Kansas City Cardiomyopathy Questionnaire overall scores occurred and were maintained at 1 year.</p><p><strong>Conclusions: </strong>In patients with complex tricuspid anatomies, TEER with the TriClip system demonstrated excellent procedural safety with significant TR reduction and associated improvements in quality of life at 1 year.</p>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2749-2760"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}