{"title":"The Unlucky Occlusion Patients Missed by the STEMI/NSTEMI Paradigm May Be Found by OMI/NOMI","authors":"Stephen W. Smith MD, Jose Nunes de Alencar MD","doi":"10.1016/j.jcin.2026.08.006","DOIUrl":"10.1016/j.jcin.2026.08.006","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2552-2554"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Timing of Nonculprit PCI for STEMI and Multivessel Disease","authors":"Mohammed A. Elbahloul MD, Islam Y. Elgendy MD","doi":"10.1016/j.jcin.2026.08.009","DOIUrl":"10.1016/j.jcin.2026.08.009","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2601-2603"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Tengfei Zheng MD, PhD, Hui Han MD, PhD, Zhongying Cao MD, Jianmin Yang MD, PhD, Chungang Zhai MD, PhD
{"title":"PCI Through the Axillary VA-ECMO Return Cannula Using a Cannula-in-Cannula Technique","authors":"Tengfei Zheng MD, PhD, Hui Han MD, PhD, Zhongying Cao MD, Jianmin Yang MD, PhD, Chungang Zhai MD, PhD","doi":"10.1016/j.jcin.2026.07.039","DOIUrl":"10.1016/j.jcin.2026.07.039","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2657-2659"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149165898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Gijs M. Broeze MSc, Hugo M. Aarts MD, Johanna da Silva Voorham MD, Kimberley I. Hemelrijk MD, Dirk Jan van Ginkel MD, Geert A.A. Versteeg MD, Maik J. Grundeken MD, PhD, Bimmer E.P.M. Claessen MD, PhD, Pim A.L. Tonino MD, PhD, Carl E. Schotborgh MD, Martijn Meuwissen MD, PhD, Gert K. van Houwelingen MD, PhD, Joanna J. Wykrzykowska MD, PhD, Giovanni Amoroso MD, PhD, Tessel N. Vossenberg MD, PhD, Pieter A. Vriesendorp MD, PhD, Niels van Royen MD, PhD, Jurriën M. ten Berg MD, PhD, Jan G.P. Tijssen PhD, Michiel Voskuil MD, PhD, Ronak Delewi MD, PhD
{"title":"Impact of Extent of Coronary Artery Disease in Transcatheter Aortic Valve Replacement","authors":"Gijs M. Broeze MSc, Hugo M. Aarts MD, Johanna da Silva Voorham MD, Kimberley I. Hemelrijk MD, Dirk Jan van Ginkel MD, Geert A.A. Versteeg MD, Maik J. Grundeken MD, PhD, Bimmer E.P.M. Claessen MD, PhD, Pim A.L. Tonino MD, PhD, Carl E. Schotborgh MD, Martijn Meuwissen MD, PhD, Gert K. van Houwelingen MD, PhD, Joanna J. Wykrzykowska MD, PhD, Giovanni Amoroso MD, PhD, Tessel N. Vossenberg MD, PhD, Pieter A. Vriesendorp MD, PhD, Niels van Royen MD, PhD, Jurriën M. ten Berg MD, PhD, Jan G.P. Tijssen PhD, Michiel Voskuil MD, PhD, Ronak Delewi MD, PhD","doi":"10.1016/j.jcin.2026.07.034","DOIUrl":"10.1016/j.jcin.2026.07.034","url":null,"abstract":"<div><h3>Background</h3><div>Coronary artery disease is present in one-half of patients undergoing transcatheter aortic valve replacement (TAVR). The recent randomized controlled PRO-TAVI (Percutaneous Coronary Intervention Before Transcatheter Aortic Valve Implantation) trial indicated that deferral of percutaneous coronary intervention (PCI) is safe in patients with concomitant coronary artery disease at 1-year follow-up. The SYNTAX (Synergy between Percutaneous Coronary Intervention with TAXUS and Cardiac Surgery) score quantifies the extent of coronary artery disease, which may guide individualized revascularization strategies.</div></div><div><h3>Objectives</h3><div>The aim of this study was to evaluate the association between SYNTAX score (SS) and clinical outcomes in patients undergoing TAVR.</div></div><div><h3>Methods</h3><div>This study was a substudy of the PRO-TAVI trial, including 466 patients with significant coronary artery disease undergoing TAVR randomized to deferral of PCI or PCI before TAVR. SS was calculated from preprocedural coronary angiograms, and patients were stratified by SS quartiles. The primary outcome was a composite of all-cause mortality, myocardial infarction, stroke, and major bleeding at 1 year. An ischemic composite outcome of all-cause mortality, myocardial infarction, and stroke was also assessed.</div></div><div><h3>Results</h3><div>The primary composite outcome did not differ across SS categories between the deferral and PCI groups at 1-year follow-up, which was completed by all but 1 patient. In patients with SS >17, the ischemic composite outcome occurred more often in the deferral group (30.9% vs 14.8%; adjusted HR: 2.43; 95% CI: 1.04-5.64; <em>P</em> = 0.04), driven primarily by all-cause mortality and stroke. Bleeding events were less frequent in the deferral group across all SS subgroups.</div></div><div><h3>Conclusions</h3><div>In patients with concomitant coronary artery disease undergoing TAVR, deferral of PCI reduced bleeding risk and appeared safe across all SS categories. Deferral of PCI in patients with more complex coronary artery disease (SS >17) was associated with higher risk for the ischemic composite outcome. These post hoc findings require confirmation in randomized trials. (Percutaneous Coronary Intervention Before Transcatheter Aortic Valve Implantation [PRO-TAVI]; <span><span>NCT05078619</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"19 19","pages":"Pages 2619-2630"},"PeriodicalIF":12.7,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149166689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}