JACC. Cardiovascular interventions最新文献

{"title":"Evaluation of the Efficacy and Limitations of the TRILUMINATE Pivotal Single-Arm Study of Tricuspid TEER.","authors":"Nina C Wunderlich","doi":"10.1016/j.jcin.2024.09.029","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.029","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2761-2763"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813239","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rethinking Thrombus Aspiration in STEMI: Balancing Efficacy and Risk.","authors":"Ahmad Hayek, Pascal Motreff, Brahim Harbaoui","doi":"10.1016/j.jcin.2024.10.026","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.026","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 23","pages":"2841"},"PeriodicalIF":11.7,"publicationDate":"2024-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142813249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intravascular Ultrasound for Guiding Venus-P-Valve Deployment.","authors":"Karol A Sadowski, Gary S Mintz, Olgierd Woźniak, Ewa Warchoł-Celińska, Elżbieta K Biernacka, Magda Lipczyńska, Piotr Hoffman, Lars Sondergaard, Marcin Demkow, Łukasz Kalińczuk","doi":"10.1016/j.jcin.2024.10.053","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.053","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":" ","pages":""},"PeriodicalIF":11.7,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Gradient Severe Aortic Stenosis Is Not Mainstream: Insights From the CURRENT AS Registry-2.","authors":"Marie-Annick Clavel, Paolo Springhetti, Philippe Pibarot","doi":"10.1016/j.jcin.2024.10.039","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.039","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":" ","pages":""},"PeriodicalIF":11.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Outcomes of Transjugular Transcatheter Tricuspid Valve Replacement.","authors":"Gennaro Giustino, Jonathan X Fang, Tiberio M Frisoli, James C Lee, Felix Nguyen, Pedro Engel, Pedro A Villablanca, William W O'Neill, Brian P O'Neill","doi":"10.1016/j.jcin.2024.10.058","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.10.058","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":" ","pages":""},"PeriodicalIF":11.7,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Low-Gradient Severe Aortic Stenosis: Insights From the CURRENT AS Registry-2.","authors":"Tomohiko Taniguchi, Takeshi Morimoto, Yasuaki Takeji, Shinichi Shirai, Kenji Ando, Hiroyuki Tabata, Ko Yamamoto, Ryosuke Murai, Kohei Osakada, Hiroki Sakamoto, Tomohisa Tada, Koichiro Murata, Yuki Obayashi, Masashi Amano, Takeshi Kitai, Chisato Izumi, Mamoru Toyofuku, Norio Kanamori, Makoto Miyake, Hiroyuki Nakayama, Masayasu Izuhara, Kazuya Nagao, Kenji Nakatsuma, Yutaka Furukawa, Moriaki Inoko, Masahiro Kimura, Mitsuru Ishii, Shunsuke Usami, Fumiko Nakazeki, Manabu Shirotani, Yasutaka Inuzuka, Koh Ono, Kenji Minatoya, Takeshi Kimura","doi":"10.1016/j.jcin.2024.09.044","DOIUrl":"https://doi.org/10.1016/j.jcin.2024.09.044","url":null,"abstract":"<p><strong>Background: </strong>Low-gradient (LG) aortic stenosis (AS) has not been fully characterized compared with high-gradient (HG) AS in terms of cardiac damage, frailty, aortic valve calcification, and clinical outcomes.</p><p><strong>Objectives: </strong>The aim of this study was to compare the clinical characteristics and outcomes between each hemodynamic type of LG AS and HG AS.</p><p><strong>Methods: </strong>The current study included 3,363 patients in the CURRENT AS (Contemporary outcomes after sURgery and medical tREatmeNT in patients with severe Aortic Stenosis) Registry-2 after excluding patients without indexed stroke volume or left ventricular ejection fraction (LVEF) data. Patients were divided into 4 groups (LG AS with reduced LVEF: n = 285; paradoxical low flow, low gradient [LFLG]: n = 220; normal flow, low gradient [NFLG]: n = 872; HG: n = 1,986).</p><p><strong>Results: </strong>Compared with HG AS, LG AS with reduced LVEF more often had cardiovascular comorbidities, advanced cardiac damage, and frailty with less severe valve calcification and paradoxical LFLG AS more often had atrial fibrillation, advanced cardiac damage, and frailty with less severe valve calcification, while NFLG AS had comparable cardiac damage and frailty with less severe valve calcification. Cumulative 3-year incidence of death or heart failure hospitalization was higher in LG AS with reduced LVEF and paradoxical LFLG than in HG AS. After adjusting for confounders, LG AS with reduced LVEF and paradoxical LFLG compared with HG AS were independently associated with higher risk for death or heart failure hospitalization (HR: 1.82; 95% CI: 1.49-2.23; P < 0.001; and HR: 1.43; 95% CI: 1.13-1.82; P = 0.003, respectively) but NFLG AS was not (HR: 1.03; 95% CI: 0.88-1.21; P = 0.68).</p><p><strong>Conclusions: </strong>Clinical outcomes were significantly worse in LG AS with reduced LVEF and paradoxical LFLG AS and comparable in NFLG AS compared with HG AS.</p>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":" ","pages":""},"PeriodicalIF":11.7,"publicationDate":"2024-11-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142872120","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Abbreviated or Standard Antiplatelet Therapy After PCI in Diabetic Patients at High Bleeding Risk","authors":"Marco Roffi MD ,&nbsp;Antonio Landi MD ,&nbsp;Dik Heg PhD ,&nbsp;Enrico Frigoli MD ,&nbsp;Konstantina Chalkou PhD ,&nbsp;Bernard Chevalier MD ,&nbsp;Alexander J.J. Ijsselmuiden MD, PhD ,&nbsp;Robert Kastberg MD ,&nbsp;Nobuyuki Komiyama MD ,&nbsp;Marie-Claude Morice MD ,&nbsp;Yoshinobu Onuma MD ,&nbsp;Yukio Ozaki MD, PhD ,&nbsp;Aaron Peace MD, PhD ,&nbsp;Stylianos Pyxaras MD, PhD ,&nbsp;Paolo Sganzerla MD ,&nbsp;Rupert Williams MD ,&nbsp;Panagiotis Xaplanteris MD ,&nbsp;Pascal Vranckx MD, PhD ,&nbsp;Stephan Windecker MD ,&nbsp;Pieter C. Smits MD, PhD ,&nbsp;Prof Ngoc Quang Nguyen","doi":"10.1016/j.jcin.2024.08.030","DOIUrl":"10.1016/j.jcin.2024.08.030","url":null,"abstract":"<div><h3>Background</h3><div>Abbreviated antiplatelet therapy (APT) reduces bleeding without increasing ischemic events in largely unselected high bleeding risk (HBR) patients undergoing percutaneous coronary intervention (PCI). Diabetes mellitus (DM) is associated with higher ischemic risk, and its impact on the safety and effectiveness of abbreviated APT in HBR PCI patients remains unknown.</div></div><div><h3>Objectives</h3><div>This study sought to investigate the comparative effectiveness of abbreviated (1 month) vs standard (≥3 months) APT in HBR patients with and without DM after biodegradable polymer sirolimus-eluting coronary stent implantation.</div></div><div><h3>Methods</h3><div>This was a prespecified analysis from the MASTER DAPT (Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With a Abbreviated Versus Prolonged DAPT Regimen) trial, which randomized 4,579 HBR patients (1,538 [34%] with DM) to abbreviated (n = 2,295) or standard (n = 2,284) APT. The coprimary outcomes were net adverse clinical events (NACEs; composite of all-cause death, myocardial infarction, stroke, and major bleeding), major adverse cardiac or cerebral events (MACCEs; all-cause death, myocardial infarction, and stroke), and major or clinically relevant nonmajor bleeding at 11 months.</div></div><div><h3>Results</h3><div>HBR patients with DM had higher risks of MACCEs (HR: 1.28; 95% CI: 1.00-1.63) and similar net adverse or bleeding events compared with nondiabetic subjects. Abbreviated compared with standard APT was associated with similar NACEs and MACCEs (<em>P</em>_interaction = 0.47 and 0.59, respectively) and reduced major or clinically relevant nonmajor bleeding (<em>P</em>_interaction = 0.55) irrespective of diabetes status.</div></div><div><h3>Conclusions</h3><div>MACCE and NACE rates were similar, and bleeding rates were lower with abbreviated APT in patients with or without diabetes. Therefore, diabetes status did not modify the treatment effects of abbreviated vs standard APT in HBR patients after biodegradable polymer sirolimus-eluting coronary stent implantation. (Management of High Bleeding Risk Patients Post Bioresorbable Polymer Coated Stent Implantation With a Abbreviated Versus Prolonged DAPT Regimen [MASTER DAPT]; <span><span>NCT03023020</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 22","pages":"Pages 2664-2677"},"PeriodicalIF":11.7,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EVOQUE Transcatheter Tricuspid Valve Replacement for Double TriClip Single-Leaflet Device Attachment","authors":"Bryan P. Traynor MBBCh BAO,&nbsp;Sami Alnasser MD,&nbsp;Gianluigi Bisleri MD,&nbsp;Geraldine Ong MD, MSc,&nbsp;Neil P. Fam MD, MSc","doi":"10.1016/j.jcin.2024.08.044","DOIUrl":"10.1016/j.jcin.2024.08.044","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 22","pages":"Pages 2701-2702"},"PeriodicalIF":11.7,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142701495","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Prognosis of Coronary Aneurysms","authors":"Iván Sánchez-Sánchez MD ,&nbsp;Enrico Cerrato MD, PhD ,&nbsp;Mario Bollati MD ,&nbsp;Carolina Espejo-Paeres MD ,&nbsp;Luis Nombela-Franco MD, PhD ,&nbsp;Emilio Alfonso-Rodríguez MD ,&nbsp;Santiago J. Camacho-Freire MD, PhD ,&nbsp;Pedro A. Villablanca MD ,&nbsp;Ignacio J. Amat-Santos MD, PhD ,&nbsp;José M. De la Torre Hernández MD, PhD ,&nbsp;Isaac Pascual MD, PhD ,&nbsp;Christoph Liebetrau MD, PhD ,&nbsp;Benjamín Camacho MD ,&nbsp;Marco Pavani MD ,&nbsp;Juan Albistur MD ,&nbsp;Roberto Adriano Latini MD ,&nbsp;Ferdinando Varbella MD ,&nbsp;Víctor Alfonso Jiménez Díaz MD ,&nbsp;Davide Piraino MD ,&nbsp;Massimo Mancone MD, PhD ,&nbsp;Iván J. Núñez-Gil MD, PhD","doi":"10.1016/j.jcin.2024.08.034","DOIUrl":"10.1016/j.jcin.2024.08.034","url":null,"abstract":"<div><h3>Background</h3><div>Limited data are available to guide the management of coronary artery aneurysms (CAAs).</div></div><div><h3>Objectives</h3><div>The authors sought to define the clinical characteristics, identify variables that predict outcomes, and provide long-term data on CAAs.</div></div><div><h3>Methods</h3><div>We describe outcomes from 1,729 consecutive patients with CAAs included in an ambispective international registry (CAAR [Coronary Artery Aneurysm Registry]; <span><span>NCT02563626</span><svg><path></path></svg></span>) involving 33 hospitals across 9 countries in America and Europe.</div></div><div><h3>Results</h3><div>Patients were predominantly male (78.6%; 1,359/1,729) with a mean age of 66 years. Classic cardiovascular risk factors were common, as well as coronary artery disease (85.8%; 1,484/1,729), peripheral vascular disease (10.9%; 188/1,729), and chronic kidney disease (8.0%; 138/1,729). The median number of aneurysms per patient was 1.0 (Q1-Q3: 1.0-1.0), with the most affected territory being the left anterior descending artery (49.6%; 857/1,729). The majority underwent any revascularization procedure (68.5%; 1,184/1,729), mainly percutaneous coronary intervention (50.7%; 877/1,729), and were discharged on dual antiplatelet therapy (65.6%; 1,134/1,729). After a median follow-up of 44.8 months (Q1-Q3: 14.9-88.1), 379 died (21.9%), and 641 (37.1%) developed a major adverse cardiovascular event (MACE) (all-cause death, heart failure, unstable angina, and reinfarction). In a multivariable analysis, age (HR: 1.03; 95% CI: 1.02-1.04; <em>P</em> &lt; 0.001), diabetes mellitus (HR: 1.47; 95% CI: 1.23-1.75; <em>P</em> &lt; 0.001), renal insufficiency (HR: 1.53; 95% CI: 1.19-1.96; <em>P</em> = 0.010), peripheral vessel disease (HR: 1.43; 95% CI: 1.13-1.82; <em>P</em> = 0.003), reduced left ventricular ejection fraction (HR: 0.98; 95% CI: 0.98-0.99; <em>P</em> &lt; 0.001), acute indication for the index coronary angiography (HR: 1.30; 95% CI: 1.08-1.55; <em>P</em> = 0.005), and the number of coronary vessels presenting severe stenosis (HR: 1.11; 95% CI: 1.02-1.20; <em>P</em> = 0.015) were independent predictors of MACEs. Remarkably, only 37 patients presented with local aneurysm complications during follow-up.</div></div><div><h3>Conclusions</h3><div>The long-term prognosis of CAAs is not favorable, with MACEs associated with the underlying risk factor profile for atherosclerotic heart disease.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 22","pages":"Pages 2681-2691"},"PeriodicalIF":11.7,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Era of Head-to-Head Comparisons of Transcatheter Heart Valves Has Begun","authors":"Nicolas M. Van Mieghem MD, PhD","doi":"10.1016/j.jcin.2024.09.053","DOIUrl":"10.1016/j.jcin.2024.09.053","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 22","pages":"Pages 2623-2625"},"PeriodicalIF":11.7,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142702535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}