JACC. Cardiovascular interventions最新文献

{"title":"Direct Electrosurgical Traversal With Radiofrequency to Prevent Obstruction in Left Ventricular Outflow Tract (DETROIT)","authors":"Jonathan X. Fang MBBS , Gennaro Giustino MD , James C. Lee MD , Brian P. O’Neill MD , Pedro Engel Gonzalez MD , Tiberio M. Frisoli MD , Dee Dee Wang MD , William W. O’Neill MD , Pedro A. Villablanca MD","doi":"10.1016/j.jcin.2024.07.017","DOIUrl":"10.1016/j.jcin.2024.07.017","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2184-2187"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145671","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transcatheter Valve-in-Valve Implantation After Transcatheter Tricuspid Valve Replacement in a Patient With Rheumatic Heart Disease","authors":"João Ferreira-Martins MD, PhD, Russell Franks MBChB, PhD, James D. Newton MB ChB, MD, Sam Dawkins MBBS, BSc, DPhil, Thomas J. Cahill MA, MBBS, DPhil","doi":"10.1016/j.jcin.2024.07.037","DOIUrl":"10.1016/j.jcin.2024.07.037","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2188-2189"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Full Issue PDF","authors":"","doi":"10.1016/S1936-8798(24)01149-X","DOIUrl":"10.1016/S1936-8798(24)01149-X","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages I-CVIII"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S193687982401149X/pdfft?md5=45a76a2543cc7bce2b5e3cbed30f9277&pid=1-s2.0-S193687982401149X-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Outcomes Following Transcatheter Mitral Valve Replacement Using Dedicated Devices in Patients With Mitral Annular Calcification","authors":"Augustin Coisne MD, PhD ,&nbsp;Sebastian Ludwig MD ,&nbsp;Andrea Scotti MD ,&nbsp;Walid Ben Ali MD, PhD ,&nbsp;Jessica Weimann MSc ,&nbsp;Alison Duncan MD ,&nbsp;John G. Webb MD ,&nbsp;Daniel Kalbacher MD ,&nbsp;Tanja K. Rudolph MD ,&nbsp;Georg Nickenig MD ,&nbsp;Jörg Hausleiter MD ,&nbsp;Hendrik Ruge MD ,&nbsp;Matti Adam MD ,&nbsp;Anna S. Petronio MD ,&nbsp;Nicolas Dumonteil MD ,&nbsp;Lars Søndergaard MD ,&nbsp;Marianna Adamo MD ,&nbsp;Damiano Regazzoli MD ,&nbsp;Andrea Garatti MD ,&nbsp;Tobias Schmidt MD ,&nbsp;Thomas Modine MD, PhD","doi":"10.1016/j.jcin.2024.07.038","DOIUrl":"10.1016/j.jcin.2024.07.038","url":null,"abstract":"<div><h3>Background</h3><div>Patients with mitral regurgitation (MR) and morphologic presence of relevant mitral annular calcification (MAC) represent a challenging phenotypic subset with limited treatment options.</div></div><div><h3>Objectives</h3><div>The aim of this study was to assess the feasibility of transcatheter mitral valve replacement (TMVR) using dedicated devices for the treatment of MAC patients.</div></div><div><h3>Methods</h3><div>Consecutive patients with symptomatic MR receiving TMVR and with available computed tomography data from the CHOICE-MI (Choice of Optimal Transcatheter Treatment for Mitral Insufficiency) multicenter registry were stratified by the presence of none or mild mitral annular calcification (MAC_none/mild) vs moderate or severe mitral annular calcification (MAC_mod/sev).</div></div><div><h3>Results</h3><div>Among 279 eligible patients (median age = 76.0 years [Q1-Q3: 71.0-81.0 years], EuroSCORE II = 6.2% [Q1-Q3: 3.9%-12.1%]), 222 (79.6%) presented with MAC_none/mild and 57 (20.4%) with MAC_mod/sev. Patients with MAC_mod/sev had a higher prevalence of extracardiac arteriopathy (<em>P =</em> 0.011) and primary MR (<em>P &lt;</em> 0.001). Although the technical success rate and the extent of MR elimination did not differ, TMVR treatment in MAC_mod/sev patients was associated with higher rates of postprocedural bleeding complications (<em>P =</em> 0.02) and renal failure (<em>P &lt;</em> 0.001). Functional improvement at the 1- and 2-year follow-up did not differ between groups. At the 2-year follow-up, there were no differences between patients with MAC_mod/sev and MAC_none/mild regarding all-cause mortality (38.5% vs 37.7%; <em>P =</em> 0.76), cardiovascular mortality (21.3% vs 24.9%; <em>P =</em> 0.97), and all-cause mortality or heart failure hospitalization (52.4% vs 46.7%; <em>P =</em> 0.28)</div></div><div><h3>Conclusions</h3><div>TMVR in patients with MAC_mod/sev is associated with higher rates of postprocedural complications but similar rates of survival, MR resolution, and functional improvement compared to MAC_none/mild. Further studies are necessary to define the role of dedicated TMVR devices in this population. (Choice of Optimal Transcatheter Treatment for Mitral Insufficiency Registry [CHOICE-MI]; <span><span>NCT04688190</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2141-2153"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"5-Year Outcomes of Anterior Mitral Leaflet Laceration to Prevent Outflow Obstruction","authors":"Jaffar M. Khan BM BCh, PhD ,&nbsp;Vasilis C. Babaliaros MD ,&nbsp;Adam B. Greenbaum MD ,&nbsp;James M. McCabe MD ,&nbsp;Toby Rogers BM BCh, PhD ,&nbsp;Marvin H. Eng MD ,&nbsp;Jason R. Foerst MD ,&nbsp;Shahram Yazdani MD ,&nbsp;Gaetano Paone MD ,&nbsp;Patrick T. Gleason MD ,&nbsp;Rim N. Halaby MD ,&nbsp;Christopher G. Bruce MB ChB ,&nbsp;Xin Tian PhD ,&nbsp;Annette M. Stine RN ,&nbsp;Robert J. Lederman MD","doi":"10.1016/j.jcin.2024.05.041","DOIUrl":"10.1016/j.jcin.2024.05.041","url":null,"abstract":"<div><h3>Background</h3><div>Left ventricular outflow tract (LVOT) obstruction is a common, often fatal complication of transcatheter mitral valve replacement (TMVR). Laceration of the anterior mitral leaflet to prevent outflow obstruction (LAMPOON) was safe and effective at preventing LVOT obstruction at 30 days in the National Heart, Lung, and Blood Institute LAMPOON trial.</div></div><div><h3>Objectives</h3><div>The authors report the 5-year outcomes of intentional anterior mitral leaflet laceration before SAPIEN 3 TMVR, in patients at risk of LVOT obstruction.</div></div><div><h3>Methods</h3><div>The National Heart, Lung, and Blood Institute LAMPOON trial was a prospective, multicenter, single-arm safety and feasibility study of LAMPOON and transseptal SAPIEN 3 TMVR in annuloplasty rings (valve-in-ring) or native mitral annular calcification (MAC) (valve-in-MAC). All subjects had high predicted risk for LVOT obstruction. Subjects were not excluded for excessive frailty or comorbidity. The primary endpoints were technical success and safety at 30 days. Secondary clinical and echocardiographic endpoints were assessed at 1 year and clinical follow-up at 5 years.</div></div><div><h3>Results</h3><div>Thirty subjects were enrolled between June 2017 and June 2018, equally between the valve-in-MAC and valve-in-ring arms. At 30 days, LAMPOON was successful in all 30 subjects, with no strokes, 1 (3%) death, and 1 (3%) moderate LVOT obstruction. Eighteen (65%) survived to 1 year, and 7 (25%) survived to 5 years. Six (20%) were hospitalized for heart failure in the first year. From baseline to 1 year, there was a 24-point improvement in Kansas City Cardiomyopathy Questionnaire score and a 60-m improvement in 6-minute walk distance. There was no significant change in N-terminal pro–brain natriuretic peptide. At 1 year, LVOT gradients remained low.</div></div><div><h3>Conclusions</h3><div>LAMPOON enabled TMVR despite the risk for LVOT obstruction. There were no long-term complications associated with LAMPOON. The selection of inoperable patients limited assessment of long-term survival following TMVR. (NHLBI DIR LAMPOON Study: Intentional Laceration of the Anterior Mitral Leaflet to Prevent Left Ventricular Outflow Tract Obstruction During Transcatheter Mitral Valve Implantation; <span><span>NCT03015194</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2157-2167"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mismatch Between Residual Mitral Regurgitation and Left Atrial Pressure Predicts Prognosis After Transcatheter Edge-to-Edge Repair","authors":"Eiji Shibahashi MD ,&nbsp;Junichi Yamaguchi MD ,&nbsp;Takanori Kawamoto MD ,&nbsp;Masafumi Yoshikawa MD ,&nbsp;Tomohito Kogure MD ,&nbsp;Yusuke Inagaki MD ,&nbsp;Chihiro Koyanagi MD ,&nbsp;Hisao Otsuki MD ,&nbsp;Masanori Yamamoto MD ,&nbsp;Mike Saji MD ,&nbsp;Shunsuke Kubo MD ,&nbsp;Masahiko Asami MD ,&nbsp;Masaki Nakashima ,&nbsp;Yusuke Enta MD ,&nbsp;Shinichi Shirai MD ,&nbsp;Masaki Izumo MD ,&nbsp;Shingo Mizuno MD ,&nbsp;Yusuke Watanabe MD ,&nbsp;Makoto Amaki MD ,&nbsp;Kazuhisa Kodama MD ,&nbsp;Kentaro Hayashida MD","doi":"10.1016/j.jcin.2024.07.046","DOIUrl":"10.1016/j.jcin.2024.07.046","url":null,"abstract":"<div><h3>Background</h3><div>The mechanism and impact of mismatch between residual mitral regurgitation (MR) and postprocedural left atrial pressure (LAP) after transcatheter edge-to-edge repair (TEER), which may adversely affect clinical outcome, is of great interest.</div></div><div><h3>Objectives</h3><div>This study aimed to examine the effect of hemodynamic mismatch after TEER on clinical outcomes in patients with heart failure due to severe MR and investigate the predictive factors for the mismatch using a prospective multicenter registry.</div></div><div><h3>Methods</h3><div>We categorized 1,477 patients into optimal (residual MR grade ≤1 and postprocedural LAP ≤15 mm Hg), mismatched (residual MR grade &gt;1 or postprocedural LAP &gt;15 mm Hg), and poor (residual MR grade &gt;1 and postprocedural LAP &gt;15 mm Hg) groups and examined their prognosis. The primary endpoint was a composite of all-cause mortality and heart failure hospitalization.</div></div><div><h3>Results</h3><div>There were 927 (62.7%), 459 (31.1%), and 91 (6.2%) patients categorized into optimal, mismatched, and poor groups, respectively. Cox regression analysis, referenced to the optimal group, revealed that the mismatched and poor groups exhibited a higher risk for the primary endpoint (HR: 1.55; 95% CI: 1.28-1.88; and HR: 1.95; 95% CI: 1.38-2.74, respectively). Six risk factors were identified as predictors of hemodynamic mismatch after TEER: body mass index, baseline left atrial volume index, atrial fibrillation, tricuspid annular plane systolic excursion value, preprocedural mean left atrial pressure, and postprocedural mean mitral valve pressure gradient.</div></div><div><h3>Conclusions</h3><div>Post-TEER hemodynamic mismatch between residual MR and postprocedural LAP was associated with a poor prognosis. Six readily accessible perioperative parameters predict the hemodynamic mismatch. (OCEAN-Mitral registry; <span><span>UMIN000023653</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2126-2137"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thinking Forward . . . and Backward","authors":"Angelo Quagliana MD, PhD,&nbsp;Giuseppe Martucci MD,&nbsp;Nicolo Piazza MD, PhD","doi":"10.1016/j.jcin.2024.08.018","DOIUrl":"10.1016/j.jcin.2024.08.018","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2138-2140"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Great Gamble","authors":"Sidakpal S. Panaich MD,&nbsp;Sameer Gafoor MD","doi":"10.1016/j.jcin.2024.08.019","DOIUrl":"10.1016/j.jcin.2024.08.019","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2180-2181"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence of High-Grade AV Block Requiring Permanent Pacemaker Implantation After TTVR","authors":"Kartik Gupta MD,&nbsp;Vardhmaan Jain MD,&nbsp;Tanya Singh Kakar MD,&nbsp;Felix Nguyen MD,&nbsp;Gautam Rangavajla MD,&nbsp;Faisal M. Merchant MD,&nbsp;Marc Lahiri MD","doi":"10.1016/j.jcin.2024.07.044","DOIUrl":"10.1016/j.jcin.2024.07.044","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2195-2196"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142312191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"TMVR With Dedicated Devices in Mitral Annular Calcification","authors":"Marco Barbanti MD,&nbsp;Federica Agnello MD","doi":"10.1016/j.jcin.2024.08.010","DOIUrl":"10.1016/j.jcin.2024.08.010","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"17 18","pages":"Pages 2154-2156"},"PeriodicalIF":11.7,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142145674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}