JACC. Cardiovascular interventions最新文献

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Coronary Stent Embolization Into a Dissected Aortic Wall 冠状动脉支架栓塞进入主动脉壁夹层。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.03.013
Christopher S. Dodgson MD , Haakon K. Grøgaard MD, PhD , Øyvind H. Lie MD, PhD
{"title":"Coronary Stent Embolization Into a Dissected Aortic Wall","authors":"Christopher S. Dodgson MD , Haakon K. Grøgaard MD, PhD , Øyvind H. Lie MD, PhD","doi":"10.1016/j.jcin.2025.03.013","DOIUrl":"10.1016/j.jcin.2025.03.013","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1479-1480"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Double Kissing Crush Coronary Stenting Technique to Treat Pulmonary Vein Stenosis 双吻挤压冠状动脉支架置入术治疗肺静脉狭窄。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.02.020
Michiel Delesie MD, PhD , Alice Benedetti MD , Nathalie Antole MD , Johan Vijgen MD , Thomas Phlips MD , Yoann Bataille MD, PhD
{"title":"Double Kissing Crush Coronary Stenting Technique to Treat Pulmonary Vein Stenosis","authors":"Michiel Delesie MD, PhD , Alice Benedetti MD , Nathalie Antole MD , Johan Vijgen MD , Thomas Phlips MD , Yoann Bataille MD, PhD","doi":"10.1016/j.jcin.2025.02.020","DOIUrl":"10.1016/j.jcin.2025.02.020","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1481-1482"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recurrent Stuck Leaflets of SAPIEN Ultra Resilia 超弹性植物的复发性粘滞小叶。
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.02.021
Toru Naganuma MD, PhD , Toru Ouchi MD , Haruhito Yuki MD , Tatsuya Nakao MD, PhD , Koji Hozawa MD
{"title":"Recurrent Stuck Leaflets of SAPIEN Ultra Resilia","authors":"Toru Naganuma MD, PhD , Toru Ouchi MD , Haruhito Yuki MD , Tatsuya Nakao MD, PhD , Koji Hozawa MD","doi":"10.1016/j.jcin.2025.02.021","DOIUrl":"10.1016/j.jcin.2025.02.021","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1471-1472"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144005629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transseptal Valve-in-Valve TMVR 经隔膜阀内TMVR
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.05.014
Marina Urena MD, PhD
{"title":"Transseptal Valve-in-Valve TMVR","authors":"Marina Urena MD, PhD","doi":"10.1016/j.jcin.2025.05.014","DOIUrl":"10.1016/j.jcin.2025.05.014","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1467-1468"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241571","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Too Sick to Be Treated? 病得无法治疗?
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.05.013
Joanna Bartkowiak MD, Fabien Praz MD
{"title":"Too Sick to Be Treated?","authors":"Joanna Bartkowiak MD, Fabien Praz MD","doi":"10.1016/j.jcin.2025.05.013","DOIUrl":"10.1016/j.jcin.2025.05.013","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1435-1437"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Right Ventricular–Pulmonary Artery Coupling in Tricuspid Regurgitation 三尖瓣反流的右心室-肺动脉耦合
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.04.033
Karl-Philipp Rommel MD , Florian Schlotter MD , Lukas Stolz MD , Karl-Patrik Kresoja MD , Mohammad Kassar MD , Fabien Praz MD , Rodrigo Estevez-Loureiro MD , Francesco Maisano MD , Eric Van Belle MD , Guillaume Bonnet MD , Daniel Kalbacher MD , Sebastian Ludwig MD , Christos Iliadis MD , Nicole Karam MD , Vera Fortmeier MD , Marianna Adamo MD , Marco Metra MD , Ralph Stephan von Bardeleben MD , Philipp Lauten MD , Peter Luedike MD , Philipp Lurz MD
{"title":"Right Ventricular–Pulmonary Artery Coupling in Tricuspid Regurgitation","authors":"Karl-Philipp Rommel MD ,&nbsp;Florian Schlotter MD ,&nbsp;Lukas Stolz MD ,&nbsp;Karl-Patrik Kresoja MD ,&nbsp;Mohammad Kassar MD ,&nbsp;Fabien Praz MD ,&nbsp;Rodrigo Estevez-Loureiro MD ,&nbsp;Francesco Maisano MD ,&nbsp;Eric Van Belle MD ,&nbsp;Guillaume Bonnet MD ,&nbsp;Daniel Kalbacher MD ,&nbsp;Sebastian Ludwig MD ,&nbsp;Christos Iliadis MD ,&nbsp;Nicole Karam MD ,&nbsp;Vera Fortmeier MD ,&nbsp;Marianna Adamo MD ,&nbsp;Marco Metra MD ,&nbsp;Ralph Stephan von Bardeleben MD ,&nbsp;Philipp Lauten MD ,&nbsp;Peter Luedike MD ,&nbsp;Philipp Lurz MD","doi":"10.1016/j.jcin.2025.04.033","DOIUrl":"10.1016/j.jcin.2025.04.033","url":null,"abstract":"<div><h3>Background</h3><div>Right ventricular–pulmonary artery coupling (RVPAC) predicts outcomes after transcatheter tricuspid valve edge-to-edge repair (T-TEER), but its role in patient selection remains unclear.</div></div><div><h3>Objectives</h3><div>The aim of this study was to evaluate the prognostic implications of RVPAC in a European registry of patients with tricuspid regurgitation undergoing either T-TEER or medical management.</div></div><div><h3>Methods</h3><div>Among 1,885 patients with tricuspid regurgitation (n = 585 medical, n = 1,300 T-TEER), 946 were propensity matched (1:1). RVPAC, assessed as the ratio of tricuspid annular plane systolic excursion to systolic pulmonary artery pressure was analyzed for its association with 1-year mortality.</div></div><div><h3>Results</h3><div>RVPAC was significantly associated with mortality (HR: 0.11; 95% CI: 0.04-0.29; <em>P</em> &lt; 0.01), with an optimized cutoff of 0.41 mm/mm Hg. Mortality differed significantly by RVPAC in both treatment groups (log-rank <em>P</em> &lt; 0.01). Across RVPAC tertiles (&lt;0.32, 0.32-0.46, and &gt;0.46 mm/mm Hg), tricuspid annular plane systolic excursion increased (14 mm [Q1-Q3: 12-17 mm] vs 18 mm [Q1-Q3: 15-20 mm] vs 21 mm [Q1-Q3: 18-24 mm]; <em>P</em> &lt; 0.01), while systolic pulmonary artery pressure (60 mm Hg [Q1-Q3: 50-70 mm Hg] vs 45 mm Hg [Q1-Q3: 40-52 mm Hg] vs 34 mm Hg [Q1-Q3: 29-41 mm Hg]; <em>P</em> = 0.30) and kidney function (43 mL/min/m<sup>2</sup> [Q1-Q3: 30-57 mL/min/m<sup>2</sup>] vs 49 mL/min/m<sup>2</sup> [Q1-Q3: 38-67 mL/min/m<sup>2</sup>] vs 53 mL/min/m<sup>2</sup> [Q1-Q3: 40-69 mL/min/m<sup>2</sup>]; <em>P</em> = 0.03) declined. Mortality was highest in the low RVPAC tertile, with no difference between treatment modalities (HR: 1.04; 95% CI: 0.68-1.61; <em>P</em> = 0.85). T-TEER was associated with better survival than medical management in the intermediate RVPAC tertile (HR: 0.54; 95% CI: 0.31-0.94; <em>P</em> = 0.03). This difference persisted but weakened in the high RVPAC tertile, with the overall most favorable outcomes (HR: 0.69; 95% CI: 0.35-1.36; <em>P</em> = 0.27).</div></div><div><h3>Conclusions</h3><div>Poorer RVPAC reflects higher baseline risk and mortality, regardless of treatment. T-TEER is associated with better survival across a range of RVPAC values, including those less than previously suggested thresholds.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1411-1421"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241456","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Right Ventricular–Pulmonary Artery Coupling in Tricuspid Transcatheter Edge-to-Edge Repair 三尖瓣经导管边缘对边缘修复中的右心室-肺动脉耦合
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.04.039
Victoria Delgado MD, PhD , Federico Fortuni MD
{"title":"Right Ventricular–Pulmonary Artery Coupling in Tricuspid Transcatheter Edge-to-Edge Repair","authors":"Victoria Delgado MD, PhD ,&nbsp;Federico Fortuni MD","doi":"10.1016/j.jcin.2025.04.039","DOIUrl":"10.1016/j.jcin.2025.04.039","url":null,"abstract":"","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1422-1424"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Long-Term Prognostic Impact of OCT-Derived High-Risk Plaque Features oct衍生的高危斑块特征对预后的长期影响
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.04.044
Flavio Giuseppe Biccirè MD , Franco Fabbiocchi MD , Laura Gatto MD, MSc , Alessio La Manna MD , Yukio Ozaki MD , Enrico Romagnoli MD, PhD , Valeria Marco RN , Alberto Boi MD , Massimo Fineschi MD , Giulio Piedimonte MD , Enrico Cerrato MD, PhD , Carmine Musto MD, PhD , Nevio Taglieri MD , Alessandro Di Giorgio MD , Giampiero Vizzari MD, PhD , Giovanni Ruscica MD , Paolo Angelo Canova MD , Rocco Vergallo MD, PhD , Francesco Burzotta MD, PhD , Ugo Limbruno MD , Francesco Prati MD
{"title":"Long-Term Prognostic Impact of OCT-Derived High-Risk Plaque Features","authors":"Flavio Giuseppe Biccirè MD ,&nbsp;Franco Fabbiocchi MD ,&nbsp;Laura Gatto MD, MSc ,&nbsp;Alessio La Manna MD ,&nbsp;Yukio Ozaki MD ,&nbsp;Enrico Romagnoli MD, PhD ,&nbsp;Valeria Marco RN ,&nbsp;Alberto Boi MD ,&nbsp;Massimo Fineschi MD ,&nbsp;Giulio Piedimonte MD ,&nbsp;Enrico Cerrato MD, PhD ,&nbsp;Carmine Musto MD, PhD ,&nbsp;Nevio Taglieri MD ,&nbsp;Alessandro Di Giorgio MD ,&nbsp;Giampiero Vizzari MD, PhD ,&nbsp;Giovanni Ruscica MD ,&nbsp;Paolo Angelo Canova MD ,&nbsp;Rocco Vergallo MD, PhD ,&nbsp;Francesco Burzotta MD, PhD ,&nbsp;Ugo Limbruno MD ,&nbsp;Francesco Prati MD","doi":"10.1016/j.jcin.2025.04.044","DOIUrl":"10.1016/j.jcin.2025.04.044","url":null,"abstract":"<div><h3>Background</h3><div>The long-term prognostic impact of presumed high-risk morphologic plaque features detected by intracoronary optical coherence tomographic (OCT) imaging remains largely unknown.</div></div><div><h3>Objectives</h3><div>The aim of this study was to assess the relationship between OCT plaque characteristics and cardiovascular outcomes throughout 5 years as part of the CLIMA (Relationship Between OCT Coronary Plaque Morphology and Clinical Outcome) study.</div></div><div><h3>Methods</h3><div>In the multicenter, international, prospective CLIMA study, 1,003 patients underwent OCT evaluation of the untreated proximal left anterior descending coronary artery. The 4 prespecified high-risk criteria were thin-cap fibroatheroma (TCFA), minimum luminal area &lt;3.5 mm<sup>2</sup>, lipid arc &gt;180°, and the presence of macrophages. The primary composite endpoint was cardiac death or target segment myocardial infarction (TS-MI).</div></div><div><h3>Results</h3><div>At 5-year follow-up (median 1,825 days; Q1-Q3: 1,137-1,825 days), the presence of all 4 OCT criteria, observed in 3.6% of patients at baseline, was independently associated with the primary endpoint (adjusted HR: 4.33; 95% CI: 2.01-9.33). The individual risks for cardiac death (HR: 3.73; 95% CI: 1.59-8.73) and TS-MI (HR: 7.02; 95% CI: 2.37-20.77) were significantly increased in patients with vs without all 4 OCT criteria. The combined presence of 4 OCT criteria remained significantly associated with the primary endpoint independently of high-intensity lipid-lowering therapy (adjusted HR: 2.94; 95% CI: 1.21-7.11). The presence of any TCFA was observed in 18.3% of patients and was similarly predictive of cardiac death and/or TS-MI.</div></div><div><h3>Conclusions</h3><div>The simultaneous presence of 4 OCT high-risk features, although infrequent, was independently associated with cardiac death or TS-MI on long-term follow-up. The presence of any TCFA was 5-fold as prevalent and similarly predictive of 5-year adverse outcomes. (Relationship Between OCT Coronary Plaque Morphology and Clinical Outcome [CLIMA]; <span><span>NCT02883088</span><svg><path></path></svg></span>)</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1361-1372"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
3-Year Outcomes of Mitral Valve-in-Valve Therapy Using Balloon-Expandable Transcatheter Valves in the United States 在美国使用球囊可扩张的经导管瓣膜进行二尖瓣中瓣治疗的3年结果
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.03.017
Mackram F. Eleid MD , Amar Krishnaswamy MD , Samir Kapadia MD , Pradeep Yadav MD , Vivek Rajagopal MD , Raj Makkar MD , Curtiss Stinis MD , Stanley Chetcuti MD , Andrew Morse MD , Tiberio Frisoli MD , Antonio H. Frangieh MD , Amr E. Abbas MD , Brian Whisenant MD , William W. O'Neill MD , Mayra E. Guerrero MD , Evelio Rodriguez MD , Susheel Kodali MD , Gorav Ailawadi MD , Charanjit S. Rihal MD
{"title":"3-Year Outcomes of Mitral Valve-in-Valve Therapy Using Balloon-Expandable Transcatheter Valves in the United States","authors":"Mackram F. Eleid MD ,&nbsp;Amar Krishnaswamy MD ,&nbsp;Samir Kapadia MD ,&nbsp;Pradeep Yadav MD ,&nbsp;Vivek Rajagopal MD ,&nbsp;Raj Makkar MD ,&nbsp;Curtiss Stinis MD ,&nbsp;Stanley Chetcuti MD ,&nbsp;Andrew Morse MD ,&nbsp;Tiberio Frisoli MD ,&nbsp;Antonio H. Frangieh MD ,&nbsp;Amr E. Abbas MD ,&nbsp;Brian Whisenant MD ,&nbsp;William W. O'Neill MD ,&nbsp;Mayra E. Guerrero MD ,&nbsp;Evelio Rodriguez MD ,&nbsp;Susheel Kodali MD ,&nbsp;Gorav Ailawadi MD ,&nbsp;Charanjit S. Rihal MD","doi":"10.1016/j.jcin.2025.03.017","DOIUrl":"10.1016/j.jcin.2025.03.017","url":null,"abstract":"<div><h3>Background</h3><div>Mitral valve-in-valve (MViV) is a safe and effective therapy for severe bioprosthetic mitral degeneration; however, longer-term outcomes are not well defined.</div></div><div><h3>Objectives</h3><div>This study aimed to evaluate 3-year outcomes following MViV.</div></div><div><h3>Methods</h3><div>Outcomes of all-cause mortality, stroke, and reintervention were collected in patients undergoing transseptal MViV with the SAPIEN 3 valve family for failed surgical bioprostheses from June 2015 to March 2024 in the TVT (Transcatheter Valve Therapy) Registry, and Centers for Medicare and Medicaid Services data linkage was performed. Kaplan-Meier and Cox proportional hazards analysis was performed according to Society of Thoracic Surgeons (STS) score and procedure status.</div></div><div><h3>Results</h3><div>A total of 5,971 patients (age 72.9 ± 11.4 years, 57.9% [n = 3457 of 5,971] female) underwent MViV. Low (&lt;4), intermediate (4-8), and high (&gt;8) STS scores were present in 23.5% (n = 1,310 of 5,585), 35.1% (n = 1,960 of 5,585) and 41.5% (n = 2,315 of 5,585) of patients, respectively. Median follow-up duration was 377 days (Q1-Q3: 57-698 days). Mortality at 3 years was greatest in high STS score and nonelective procedures, while mortality was lowest in low STS score patients and elective procedures. Stroke rates at 3 years were comparable except between low and high STS groups. Mitral valve reintervention during 3 years of follow-up was uncommon in all groups.</div></div><div><h3>Conclusions</h3><div>Three-year survival after MViV is highest in low STS scores and elective procedures, whereas survival was significantly lower in high STS scores and nonelective procedures. These findings emphasize the importance of early identification and treatment of patients who may benefit from MViV. Reintervention rates at 3 years are low regardless of STS score.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1454-1466"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Procedural Impact of Advanced Calcific Plaque Modification Devices Within Percutaneous Revascularization of Chronic Total Occlusions 先进的钙化斑块改良装置对经皮慢性全闭塞血运重建术的程序影响
IF 11.7 1区 医学
JACC. Cardiovascular interventions Pub Date : 2025-06-09 DOI: 10.1016/j.jcin.2025.04.035
Giuseppe Vadalà MD , Kambis Mashayekhi MD, PhD , Michael Behnes MD, PhD , Mohamed Ayoub MD , Sevket Gorgulu MD, PhD , Gerald S. Werner MD, PhD , Nihat Kalay MD , Alexander Avran MD , Omer Goktekin MD , Roberto Garbo MD , Wojcik Jaroslaw MD, PhD , Myron Zaczkiewicz MD , Juergen Arnez MD , Stylianos Pyxaras MD, PhD , Evald Høj Christiansen MD, PhD , Juan Luis Gutiérrez-Chico MD, PhD , Laura Maniscalco PhD , Cristina Madaudo MD , Nicolaus Boudou MD , Sinisa Stojkovic MD, PhD , Alfredo R. Galassi MD
{"title":"Procedural Impact of Advanced Calcific Plaque Modification Devices Within Percutaneous Revascularization of Chronic Total Occlusions","authors":"Giuseppe Vadalà MD ,&nbsp;Kambis Mashayekhi MD, PhD ,&nbsp;Michael Behnes MD, PhD ,&nbsp;Mohamed Ayoub MD ,&nbsp;Sevket Gorgulu MD, PhD ,&nbsp;Gerald S. Werner MD, PhD ,&nbsp;Nihat Kalay MD ,&nbsp;Alexander Avran MD ,&nbsp;Omer Goktekin MD ,&nbsp;Roberto Garbo MD ,&nbsp;Wojcik Jaroslaw MD, PhD ,&nbsp;Myron Zaczkiewicz MD ,&nbsp;Juergen Arnez MD ,&nbsp;Stylianos Pyxaras MD, PhD ,&nbsp;Evald Høj Christiansen MD, PhD ,&nbsp;Juan Luis Gutiérrez-Chico MD, PhD ,&nbsp;Laura Maniscalco PhD ,&nbsp;Cristina Madaudo MD ,&nbsp;Nicolaus Boudou MD ,&nbsp;Sinisa Stojkovic MD, PhD ,&nbsp;Alfredo R. Galassi MD","doi":"10.1016/j.jcin.2025.04.035","DOIUrl":"10.1016/j.jcin.2025.04.035","url":null,"abstract":"<div><h3>Background</h3><div>Significant calcifications within a coronary chronic total occlusion (CTO) increase procedural complexity and the risk for complications. Expert consensus documents recommend the use of advanced calcific plaque modification devices (ACPMDs) for calcified CTO percutaneous coronary intervention (PCI), whereas data on their procedural impact are limited.</div></div><div><h3>Objectives</h3><div>The aim of this study was to describe trends, settings, and outcomes of PCI of severely calcified CTO performed with and without ACPMDs.</div></div><div><h3>Methods</h3><div>Data from 15,329 CTO PCIs enrolled in the ERCTO (European Registry of Chronic Total Occlusion) between 2021 and 2023 were analyzed. On the basis of the presence of severe calcifications within the CTO, the study population was divided into 2 groups: nonsevere (n = 12,289) and severe (n = 3,040) calcium. Then, the severe group was divided into non-ACPMD (n = 2,253) and ACPMD (n = 787), according to the use of ACPMDs.</div></div><div><h3>Results</h3><div>Compared with the non-ACPMD group, the ACPMD group had higher rates of antegrade wiring (77.9% vs 49.2%; <em>P</em> &lt; 0.001) and technical success (97.6% vs 79.1%; <em>P</em> = 0.001) and lower rates of periprocedural and in-hospital major adverse cardiac and cerebrovascular events (MACCE) (1.8% vs 3.5%; <em>P</em> = 0.001). A severe amount of calcium was independently associated with technical failure (OR: 3.13; 95% CI: 2.43-4.09; <em>P</em> &lt; 0.001) but not with MACCE (OR: 0.88; 95% CI: 0.58-1.35; <em>P</em> = 0.15). Furthermore, extraplaque crossing was independently associated with MACCE (antegrade dissection and re-entry without retrograde contribution: OR: 3.12; 95% CI: 1.79-4.20; <em>P</em> &lt; 0.001; antegrade dissection and re-entry with retrograde contribution: OR: 3.12; 95% CI: 1.67-4.11; <em>P</em> = 0.049; retrograde dissection and re-entry: OR: 1.90; 95% CI: 1.25-2.86; <em>P</em> = 0.002).</div></div><div><h3>Conclusions</h3><div>Applying ACPMDs in severely calcified CTO to PCI was associated with higher technical success and lower MACCE rates. The presence of severe coronary calcification on coronary angiography was a marker of clinical and procedural complexity and was associated with technical failure but not with MACCE.</div></div>","PeriodicalId":14688,"journal":{"name":"JACC. Cardiovascular interventions","volume":"18 11","pages":"Pages 1376-1390"},"PeriodicalIF":11.7,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144241576","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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