Japanese journal of infectious diseases最新文献_第2页

Gastric cancer and associated pathogens: is there any association in Moroccan region? 胃癌与相关病原体：摩洛哥地区是否存在关联？

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-10-31 DOI: 10.7883/yoken.JJID.2024.147

Samia Alaoui Boukhris, Mounia El Khadir, Safae Karim, Tiatou Souho, Dafr-Allah Benajah, Sidi Adil Ibrahimi, Laila Chbani, Mohamed El Abkari, Bahia Bennani

{"title":"Gastric cancer and associated pathogens: is there any association in Moroccan region?","authors":"Samia Alaoui Boukhris, Mounia El Khadir, Safae Karim, Tiatou Souho, Dafr-Allah Benajah, Sidi Adil Ibrahimi, Laila Chbani, Mohamed El Abkari, Bahia Bennani","doi":"10.7883/yoken.JJID.2024.147","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.147","url":null,"abstract":"Helicobacter pylori, Epstein-Barr virus and human papillomavirus are three pathogens associated with various human cancers. This study aimed to investigate the role of these pathogens in gastric cancer in Moroccan population. For this, a retrospective study has been conducted on participants attending the gastroenterology department of Hassan II University Hospital of Fez. A total of 279 participants were enrolled. H. pylori, EBV and HPV were detected and genotyped by PCR. In results, a significant association has been established between H. pylori, EBV and gastric cancer. 93.4% and 43.3% of gastric cancer cases are related to H. pylori and EBV respectively (p≤0.01). H. pylori-EBV co-infection is responsible of 31.6% of gastric cancer cases (p<0.01). Correlation between pathogens genotypes and gastric cancer shows 54.6% of GC EBV positives are carrying the 30 bp deletion in LMP1gene, while 16% of gastric cancers cases are carrying high-risk genotypes of HPV (p=0.21). The obtained results highlight the possible role of co-infection in gastric cancer development.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545484","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Chemotactic activity of products of Elizabethkingia anophelis derived from Aedes albopictus against RAW264 murine macrophage cell line. 从白纹伊蚊中提取的 Elizabethkingia anophelis 产品对 RAW264 鼠巨噬细胞系的趋化活性。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-10-31 DOI: 10.7883/yoken.JJID.2024.227

Satoru Yui, Norihiko Fujii, Jo Terauchi, Nana Tanabe, Marie Kanno, Kouta Umehara, Ryosuke Iijima, Riyo Kamata, Naoki Ohkura, Seishi Kishimoto, Toshinori Sasaki

{"title":"Chemotactic activity of products of Elizabethkingia anophelis derived from Aedes albopictus against RAW264 murine macrophage cell line.","authors":"Satoru Yui, Norihiko Fujii, Jo Terauchi, Nana Tanabe, Marie Kanno, Kouta Umehara, Ryosuke Iijima, Riyo Kamata, Naoki Ohkura, Seishi Kishimoto, Toshinori Sasaki","doi":"10.7883/yoken.JJID.2024.227","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.227","url":null,"abstract":"Dengue viruses enter dermal macrophages which are derived from other tissues after mosquito bites. We examined chemotactic factors derived from the dengue vector mosquito, Aedes albopictus, toward a RAW264 murine macrophage cell line. We found that Elizabethkingia anophelis that was isolated from mosquitoes exhibited migration-inducing activity toward RAW264 cells. The active substances were extracted using ethyl acetate to induce chemotactic movements. Chemotactic activity was eluted in the several fractions using the reversed-phase chromatography, suggesting that multiple substances were responsible for the activity. We isolated three bacterial colonies from the wild A. albopictus mosquitoes collected in Toyama Park, Tokyo prefecture, Japan. The bacterial 16S rRNA gene sequences were the most similar to those of Lonsdalea quercina. These bacteria also exhibited migration-inducing activity toward RAW264 cells. The migration-inducing activity of mosquito bacteria might be a new aspect of mosquito-mediated viral infections.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics and Risk Factors for Severe Japanese Spotted Fever: A Retrospective Multicenter Study in Nagasaki Prefecture, Western Japan. 严重日本斑疹热的临床特征和风险因素：日本西部长崎县的一项回顾性多中心研究。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-10-31 DOI: 10.7883/yoken.JJID.2024.216

Kohsuke Matsui, Shingo Masuda, Yosuke Koizumi, Monami Yamanaka, Yasumori Izumi, Chris Smith, Reiko Miyahara, Koya Ariyoshi

{"title":"Clinical Characteristics and Risk Factors for Severe Japanese Spotted Fever: A Retrospective Multicenter Study in Nagasaki Prefecture, Western Japan.","authors":"Kohsuke Matsui, Shingo Masuda, Yosuke Koizumi, Monami Yamanaka, Yasumori Izumi, Chris Smith, Reiko Miyahara, Koya Ariyoshi","doi":"10.7883/yoken.JJID.2024.216","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.216","url":null,"abstract":"Japanese spotted fever (JSF) is a tick-borne rickettsial disease prevalent in western Japan, with an increasing incidence and geographical distribution. This retrospective study aimed to describe the clinical features of JSF and identify factors associated with its severe form. We included adult patients with laboratory confirmed JSF in Nagasaki prefecture from 2010 to 2021. Severe JSF was defined by the presence of altered mental status, low blood pressure, or low oxygen saturation. In total, 65 JSF cases were diagnosed. Common symptoms were fever (87%), rash (48%), and fatigue (48%) with eschars detected in 50 (79.4%) of patients. Thirty-eight (60.3%) patients were initially diagnosed with non-JSF conditions. Twenty-one (33.3%) cases were categorized as severe JSF, including one death. Pre-hospital factors associated with severe JSF included age ≥75 (adjusted odds ratio [aOR] 37.53, 95% confidence interval [CI] 3.03-465.38), male sex (aOR 26.5, 95% CI 4.23-166.00), and a treatment delay ≥4 days from onset (aOR 5.96, 95% CI 1.13-31.60). This study highlights diagnostic challenges of JSF due to its non-organ-specific clinical presentation. Delayed initial treatment, advanced age, and male sex significantly increase the risk of severity. It is crucial to further raise awareness of JSF among clinicians and residents in endemic areas.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-10-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Septic shock and death due to Dolosigranulum pigrum bacteremia: a case report. 猪多糖菌血症导致的脓毒性休克和死亡：病例报告。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-10-31 DOI: 10.7883/yoken.JJID.2024.178

Sachiko Hakoda, Akira Ishiwata, Ryo Shimada, Shuji Hatakeyama, Makoto Kondo

引用次数: 0

Investigation of the outbreak of Clostridium perfringens using single nucleotide polymorphism analysis for genotyping in Toyama, Japan, 2023. 利用单核苷酸多态性分析进行基因分型的日本富山梭状芽孢杆菌疫情调查，2023 年。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-09-30 DOI: 10.7883/yoken.JJID.2024.189

Kazuki Saito, Keiko Kimata, Masanori Watahiki, Junko Isobe, Jun-Ichi Kanatani, Kaho Ikeda, Takashi Takeuchi, Chiharu Matsuzaki, Kazunori Oishi

{"title":"Investigation of the outbreak of Clostridium perfringens using single nucleotide polymorphism analysis for genotyping in Toyama, Japan, 2023.","authors":"Kazuki Saito, Keiko Kimata, Masanori Watahiki, Junko Isobe, Jun-Ichi Kanatani, Kaho Ikeda, Takashi Takeuchi, Chiharu Matsuzaki, Kazunori Oishi","doi":"10.7883/yoken.JJID.2024.189","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.189","url":null,"abstract":"Clostridium perfringens, which produces C. perfringens enterotoxin (CPE), is a major causative agent of food poisoning owing to its gastrointestinal symptoms. Genotyping is important for identifying the etiological agent in outbreaks of C. perfringens. We attempted to genotype strains isolated from an outbreak of food poisoning in Toyama in 2023 using single nucleotide polymorphism (SNP) analysis. The strains of C. perfringens were isolated from a piece of curry food consumed by all patients and from the feces of the patients and employees. The cpe gene was detected in isolates from patients and curry food. The cpe-negative isolates were found in patients who consumed curry foods and in employees. The results of the SNP analysis suggest that the patient- and curry-derived isolates were likely from the same source but were unlikely to be related to the employee-derived isolates. The results of the SNP and pulsed-field gel electrophoresis (PFGE) analyses were consistent, indicating that the patient- and curry-derived isolates came from the same source. SNP analysis, a whole-genome-based genotyping method, is a promising alternative to the traditional PFGE method. Further studies are needed to accumulate more experience with genotyping using SNP analysis for the epidemiological investigation of outbreaks of C. perfringens.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

SARS-CoV-2 IgG seroprevalence in the Okinawa Main Island and remote islands in Okinawa, Japan, 2020-2021. 2020-2021 年日本冲绳本岛和冲绳偏远岛屿的 SARS-CoV-2 IgG 血清流行率。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-09-30 DOI: 10.7883/yoken.JJID.2023.255

Yoshihiro Takayama, Yusuke Shimakawa, Yoshiaki Aizawa, Christian Butcher, Naomi Chibana, Mary Collins, Kohei Kamegai, Tae Gyun Kim, Satoshi Koyama, Ryota Matsuyama, Melissa M Matthews, Tomoari Mori, Tetsuharu Nagamoto, Masashi Narita, Ryosuke Omori, Noriko Shibata, Satoshi Shibata, Souichi Shiiki, Shunichi Takakura, Naoki Toyozato, Hiroyuki Tsuchiya, Matthias Wolf, Taro Yamamoto, Shuhei Yokoyama, Sho Yonaha, Kenji Mizumoto

{"title":"SARS-CoV-2 IgG seroprevalence in the Okinawa Main Island and remote islands in Okinawa, Japan, 2020-2021.","authors":"Yoshihiro Takayama, Yusuke Shimakawa, Yoshiaki Aizawa, Christian Butcher, Naomi Chibana, Mary Collins, Kohei Kamegai, Tae Gyun Kim, Satoshi Koyama, Ryota Matsuyama, Melissa M Matthews, Tomoari Mori, Tetsuharu Nagamoto, Masashi Narita, Ryosuke Omori, Noriko Shibata, Satoshi Shibata, Souichi Shiiki, Shunichi Takakura, Naoki Toyozato, Hiroyuki Tsuchiya, Matthias Wolf, Taro Yamamoto, Shuhei Yokoyama, Sho Yonaha, Kenji Mizumoto","doi":"10.7883/yoken.JJID.2023.255","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2023.255","url":null,"abstract":"We estimated the seroprevalence of anti-SARS-COV-2 IgG in different island groups in Okinawa. A cross-sectional sero-survey was repeated in three periods between July 2020 and February 2021. A total of 2683 serum samples were collected from six referral medical centers, each covering a separate region in Okinawa. In the main island, the seroprevalence was 0.0% (0/392, 95% CI: 0.0-0.9), 0.6% (8/1448, 0.2-1.1), and 1.4% (8/582, 0.6-2.7) at the 1st, 2nd, and 3rd sero-survey, respectively. In the remote islands, the seroprevalence was 0.0% (0/144, 95% CI: 0.0-2.5) and 1.6% (2/123, 0.2-5.8) at the 2nd and 3rd survey, respectively. The case detection ratio was 2.7 (95% CI: 1.3-5.3) in the main island and 2.8 (0.7-11.1) in the remote islands during the 3rd survey. The case detection ratio was the highest in people aged 20-29 years (8.3, 95% CI: 3.3-21.4) in the main island and in those aged 50-59 years (14.1, 2.1-92.7) in the remote islands, suggesting under-reporting of clinical cases by the surveillance system in these subgroups. A sero-survey during an emerging infectious disease epidemic can be useful for validating the reliability of the surveillance system by providing the case detection ratio.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Risk of death in old Japanese COVID-19 cases infected with the Omicron variant: a population-based study. 日本 COVID-19 老年病例感染 Omicron 变体的死亡风险：一项基于人群的研究。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-09-30 DOI: 10.7883/yoken.JJID.2024.071

Hideo Tanaka, Yuki Takahashi, Yoshitaka Koga, Shunichi Takiguchi, Shigeru Ogimoto, Shizuyo Inaba, Hiroyuki Matsuoka, Yuka Miyajima, Takeshi Takagi, Fujiko Irie, Yoshihito Bamba, Fuyo Yoshimi, Tomoyuki Suzuki, Isao Araki, Chika Shirai, Sayuri Matsumoto, Toshiyuki Shibata, Hitomi Nagai, Masaru Kinoshita, Rie Fujita, Tsuyoshi Ogata

{"title":"Risk of death in old Japanese COVID-19 cases infected with the Omicron variant: a population-based study.","authors":"Hideo Tanaka, Yuki Takahashi, Yoshitaka Koga, Shunichi Takiguchi, Shigeru Ogimoto, Shizuyo Inaba, Hiroyuki Matsuoka, Yuka Miyajima, Takeshi Takagi, Fujiko Irie, Yoshihito Bamba, Fuyo Yoshimi, Tomoyuki Suzuki, Isao Araki, Chika Shirai, Sayuri Matsumoto, Toshiyuki Shibata, Hitomi Nagai, Masaru Kinoshita, Rie Fujita, Tsuyoshi Ogata","doi":"10.7883/yoken.JJID.2024.071","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.071","url":null,"abstract":"We assessed case fatality rates (CFRs) in cases aged ≥70 years in 10 Japanese prefectures (14.8 million residents) diagnosed between January 2022 and March 2023, when the Omicron variant was dominant in Japan. We selected incident reports on 283,052 study subjects from participating Public Health Centers adhering to the Infectious Diseases Control Law. Cases were passively followed up until the end of their isolation, date of death or 28 days after the COVID-19 diagnosis, whichever occurred first. We calculated age-standardized CFRs with 95% confidence intervals (CI) using the Japanese population aged 70-79, 80-89 and ≥90 in 2022 divided into 16 subgroups according to the period of COVID-19 diagnosis. The total overall CFR was 1.59% (95% CI 1.55-1.64); it ranged between 0.67% (95% CI 0.38-0.96, May 23-June 19) and 2.58% (95% CI 2.36-2.80, January 31-February 27). We observed three peaks of age-standardized CFRs paralleling the 6th, 7th and 8th endemic COVID-19 waves driven by Omicron in Japan (2.2% January 31-February 27, 1.0% July 18-August 14 and 1.6% December 26-January 22, 2023, respectively). Population-based CFRs for Omicron variant COVID-19 in Japanese aged ≥70 years remained <3% throughout the period January 2022-March 2023, including during three large endemic waves in this country.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346835","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic diversity and potential transmission of Escherichia albertii in a poultry breeding rural village. 一个家禽养殖农村的白细胞埃希氏菌遗传多样性和潜在传播途径。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-09-30 DOI: 10.7883/yoken.JJID.2024.209

Peihua Zhang, Guodong Yan, Qian Liu, Xi Yang, Jie Zhang, Xi Chen, Hong Wang, Ling Zhang, Xinxia Sui, Xiangning Bai, Yanwen Xiong, Zhengdong Zhang

{"title":"Genetic diversity and potential transmission of Escherichia albertii in a poultry breeding rural village.","authors":"Peihua Zhang, Guodong Yan, Qian Liu, Xi Yang, Jie Zhang, Xi Chen, Hong Wang, Ling Zhang, Xinxia Sui, Xiangning Bai, Yanwen Xiong, Zhengdong Zhang","doi":"10.7883/yoken.JJID.2024.209","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.209","url":null,"abstract":"Escherichia albertii is an emerging foodborne pathogen causing diarrhea. Though various animals, especially poultry, serve as reservoirs, the transmission of E. albertii among reservoirs and the risk to humans remain unclear. This study investigated an E. albertii infected infant with poultry exposure and collected samples from contact persons, poultries, and environment to better understand the transmission dynamics of E. albertii. One E. albertii isolate from contact person, seven isolates from poultries, and six isolates from environment were recovered, respectively. Whole genome sequencing analysis showed that eight strains derived from poultry or environment and classified as ST4633, shared great similarity (cgSNP ≤ 20). However, the patient-derived strain ESA311 had a cgSNP difference of 1165 with human strain ESA339, and differed from poultry and environmental strains (cgSNP range 2417 to 14997), suggesting a distant relatedness. Whole genome phylogeny showed several human-derived E. albertii strains were clustered with those from animal origins. Our results suggested that family-breeding poultry constituted a possible reservoir of E. albertii, with the environment acting as a crucial vector for the spread of these bacteria, posing a risk to humans. Further poultry surveillance is needed to elucidate public health risks associated with E. albertii infection.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Respiratory syncytial virus infection notification trends and interpretation of the reported case data, 2018-2021, Japan. 2018-2021 年日本呼吸道合胞病毒感染通报趋势及病例报告数据解读。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-09-30 DOI: 10.7883/yoken.JJID.2024.187

Miyako Otsuka, Ayu Kasamatsu, Yuzo Arima, Takuri Takahashi, Takeshi Arashiro, Katsuhiro Komase, Reiko Shimbashi, Yuuki Tsuchihashi, Yusuke Kobayashi, Osamu Takahara, Kazuhiko Kanou, Motoi Suzuki

{"title":"Respiratory syncytial virus infection notification trends and interpretation of the reported case data, 2018-2021, Japan.","authors":"Miyako Otsuka, Ayu Kasamatsu, Yuzo Arima, Takuri Takahashi, Takeshi Arashiro, Katsuhiro Komase, Reiko Shimbashi, Yuuki Tsuchihashi, Yusuke Kobayashi, Osamu Takahara, Kazuhiko Kanou, Motoi Suzuki","doi":"10.7883/yoken.JJID.2024.187","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.187","url":null,"abstract":"In Japan, as elsewhere, the COVID-19 pandemic affected the notification trends of respiratory syncytial virus (RSV) infection. Here, we describe the epidemiological trends of RSV cases among children reported during 2018-2021 in Japan, based on the national surveillance system. Compared to 2018 and 2019, 2020 saw an unprecedented decrease in RSV notifications per sentinel site. However, 2021 experienced an unseasonably early and high peak in week 28 (peak week in 2018 and 2019: week 37) with a large resurgence in notifications, nationwide and across regions. Regarding age, compared to 2018 and 2019, the number and proportion of cases aged 2, 3, and ≥4-years increased substantially in 2021 but the number of cases aged <1 year decreased slightly. Furthermore, in 2021, the ratio of notifications per site from outpatient clinics to hospitals increased, suggesting a proportionate increase in clinically milder case diagnoses. Notably, RSV-attributed deaths from vital statistics also dropped substantially in 2020 and rebounded in 2021, but were fewer than in 2018 or 2019. While RSV incidence likely declined in 2020 (possibly from COVID-19 countermeasures) and increased in 2021, notifications in 2021 appeared to be associated with milder presentations. Given unpredictable RSV epidemiology, continuous monitoring and pluralistic assessments are imperative.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346834","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of prognosis in patients with severe fever with thrombocytopenia syndrome. 预测严重发热伴血小板减少综合征患者的预后。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2024-09-30 DOI: 10.7883/yoken.JJID.2024.015

Yi Zhang, Lingtong Huang, Zheyue Shu, Wei Wu, Hongliu Cai, Yu Shi

{"title":"Prediction of prognosis in patients with severe fever with thrombocytopenia syndrome.","authors":"Yi Zhang, Lingtong Huang, Zheyue Shu, Wei Wu, Hongliu Cai, Yu Shi","doi":"10.7883/yoken.JJID.2024.015","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.015","url":null,"abstract":"This study aims to understand the clinical characteristics of severe fever with thrombocytopenia syndrome (SFTS) and screen risk factors for the prognosis. This retrospective study collected the epidemiological, demographic, and clinical and laboratory data of 101 patients with SFTS. Patients were divided into survival and deceased groups, and then logistic regression model was used to evaluate the association between predictors and prognostic variables. A joint detection factor model was constructed, and a receiver operating characteristic (ROC) curve was drawn. A nomogram was established using the R language, and its efficiency in the diagnosis of SFTS was evaluated using the Calibrate curve. Patients in the deceased group were more likely to show an elder age, a shorter hospitalization stay, renal failure and multiple organ failure compared with that of the survival group. There were statistical differences in the neutrophil percentage, lymphocyte percentage, neutrophil-to-lymphocyte ratio, platelet (PLT), AST, AST/ALT, blood urea nitrogen, lactate dehydrogenase, hydroxybutyrate dehydrogenase, thromboplastin time and activated partial thromboplastin time between the two groups. Lymphocyte percentage, PLT, and AST/ALT were independent risk factors for mortality in SFTS patients. We established a prediction model for SFTS mortality with good efficiency.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346833","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0