Japanese journal of infectious diseases最新文献_第2页

Utilizing Infectious Disease Surveillance for Epidemic Warnings of Respiratory Syncytial Virus Infections in Japan from 2015 to 2019. 2015 - 2019年日本呼吸道合胞病毒感染的传染病监测预警

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-03-21 Epub Date: 2024-12-27 DOI: 10.7883/yoken.JJID.2023.484

Akiko Ohta, Shuji Hashimoto, Miyuki Kawado, Mari S Oba, Ritei Uehara, Kiyosu Taniguchi, Tomimasa Sunagawa, Masaki Nagai, Yoshitaka Murakami

{"title":"Utilizing Infectious Disease Surveillance for Epidemic Warnings of Respiratory Syncytial Virus Infections in Japan from 2015 to 2019.","authors":"Akiko Ohta, Shuji Hashimoto, Miyuki Kawado, Mari S Oba, Ritei Uehara, Kiyosu Taniguchi, Tomimasa Sunagawa, Masaki Nagai, Yoshitaka Murakami","doi":"10.7883/yoken.JJID.2023.484","DOIUrl":"10.7883/yoken.JJID.2023.484","url":null,"abstract":"Japan's National Epidemiological Surveillance of Infectious Diseases (NESID) has implemented a warning system for detecting epidemics in smaller districts, such as public health center (PHC) areas. This system is applied to influenza and pediatric infectious diseases. Respiratory syncytial virus (RSV) infection is not included but its incorporation is needed for effective early epidemic detection. We aimed to propose criterion values for an epidemic warning system related to RSV infection within PHC areas. We analyzed the weekly number of RSV infection cases reported by sentinel medical institutions (SMIs) in the NESID from 2015 to 2019. Weekly cases per SMI in the PHC area were set to establish an index for epidemic warnings. We determined criteria for issuing an epidemic warning by identifying distribution percentiles within the index. Setting the critical values for the onset and end of the epidemic warning at 5 and 2, respectively, yielded an approximately 5% annual proportion of PHC areas with an epidemic warning, which aligns with previously accepted frequency criteria for epidemic warnings. The 5-year (2015-2019) RSV infection epidemic trend showed that the set critical values were appropriate. Using these values could assist with issuing warnings regarding potential RSV infection epidemics in Japan.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":"114-117"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142931734","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Differences in Characteristics, Treatments, and Mortality of Patients with COVID-19 Between 2022 and 2020-2021. 2022年和2020-2021年间COVID-19患者特征、治疗和死亡率的差异。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-03-21 Epub Date: 2024-11-29 DOI: 10.7883/yoken.JJID.2024.272

Shotaro Aso, Sachiko Ono, Nobuaki Michihata, Kohei Uemura, Hideo Yasunaga

{"title":"Differences in Characteristics, Treatments, and Mortality of Patients with COVID-19 Between 2022 and 2020-2021.","authors":"Shotaro Aso, Sachiko Ono, Nobuaki Michihata, Kohei Uemura, Hideo Yasunaga","doi":"10.7883/yoken.JJID.2024.272","DOIUrl":"10.7883/yoken.JJID.2024.272","url":null,"abstract":"In 2021, vaccines against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) were developed and the Omicron variant emerged. This study compared the characteristics, treatments, and mortality of patients with coronavirus disease 2019 (COVID-19) between 2022 and 2020-2021, using administrative claims data linked including vaccine records in a Japanese city. Patients who underwent COVID-19 antigen or polymerase chain reaction tests and were diagnosed with COVID-19 were identified. Patient characteristics, treatments, and mortality were compared between 2022 and 2020-2021 among those diagnosed with COVID-19. We identified 26,262 patients with COVID-19. The mortality in 2022 was lower than that in 2020-2021 (0.6% vs. 1.7%; P < 0.01). Patients in 2022 were significantly less likely to receive oxygen therapy, high-flow nasal oxygenation, mechanical ventilation, steroids, and tocilizumab than those in 2020-2021. Among the deceased, the proportion of those aged ≥65 years was significantly higher in 2022 than in 2020-2021 (98.4% vs. 88.6%). The logistic regression analysis indicated, older age, male sex, and ≥3 comorbidities were associated with higher mortality, whereas ≥3 vaccinations were associated with lower mortality. Patients with COVID-19 in 2022 were less likely to require respiratory care or succumb to the disease. Older patients were more likely to die in 2022 than in 2020-2021.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":"85-90"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142769015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical Characteristics and Risk Factors for Severe Japanese Spotted Fever: A Retrospective Multicenter Study in the Nagasaki Prefecture, Western Japan. 严重日本斑疹热的临床特征和风险因素：日本西部长崎县的一项回顾性多中心研究。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-03-21 Epub Date: 2024-10-31 DOI: 10.7883/yoken.JJID.2024.216

Kohsuke Matsui, Shingo Masuda, Yosuke Koizumi, Monami Yamanaka, Yasumori Izumi, Chris Smith, Reiko Miyahara, Koya Ariyoshi

{"title":"Clinical Characteristics and Risk Factors for Severe Japanese Spotted Fever: A Retrospective Multicenter Study in the Nagasaki Prefecture, Western Japan.","authors":"Kohsuke Matsui, Shingo Masuda, Yosuke Koizumi, Monami Yamanaka, Yasumori Izumi, Chris Smith, Reiko Miyahara, Koya Ariyoshi","doi":"10.7883/yoken.JJID.2024.216","DOIUrl":"10.7883/yoken.JJID.2024.216","url":null,"abstract":"Japanese spotted fever (JSF) is a tick-borne rickettsial disease prevalent in western Japan with an increasing incidence and geographical distribution. This retrospective study aimed to describe the clinical features of JSF and identify factors associated with its severe form. We included adult patients with laboratory-confirmed JSF in the Nagasaki Prefecture between 2010 and 2021. Severe JSF was defined as an altered mental status, low blood pressure, or low oxygen saturation. In total, 65 JSF cases were diagnosed. Common symptoms included fever (87%), rash (48%), and fatigue (48%), with eschars detected in 50 (79.4%) patients. Thirty-eight (60.3%) patients were initially diagnosed with non-JSF conditions. Twenty-one (33.3%) patients were categorized as having severe JSF, including one death. Prehospital factors associated with severe JSF included age ≥75 (adjusted odds ratio [aOR] 37.53, 95% confidence interval [CI] 3.03-465.38), male sex (aOR 26.5, 95% CI 4.23-166.00), and a treatment delay ≥4 days from onset (aOR 5.96, 95% CI 1.13-31.60). This study highlights the diagnostic challenges of JSF owing to its non-organ-specific clinical presentation. Delayed initial treatment, advanced age, and male sex significantly increase the risk of disease severity. It is crucial to raise awareness of JSF among clinicians and residents in endemic areas.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":"63-70"},"PeriodicalIF":1.3,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142545483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sensitivity evaluation of a modified real-time reverse-transcription PCR primer to detect a measles virus variant in Japan in 2024. 改良实时反转录 PCR 引物检测 2024 年日本麻疹病毒变种的灵敏度评估。

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-02-28 DOI: 10.7883/yoken.JJID.2024.304

Takako Kurata, Daiki Kanbayashi, Atsushi Kaida, Saeko Morikawa, Satoshi Hiroi, Yuki Hirai, Mei Koyama, Takeshi Miyama, Noriyuki Otsuki, Kazushi Motomura

引用次数: 0

Evaluation of the shortened quarantine policy among healthcare personnel in the cancer center setting during the Omicron epidemic in Japan: A descriptive epidemiological study.

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-02-28 DOI: 10.7883/yoken.JJID.2024.204

Yuka Kudo-Nagata, Takahiro Ozawa, Tami Watanabe, Masako Sakurada, Noritaka Sekiya

{"title":"Evaluation of the shortened quarantine policy among healthcare personnel in the cancer center setting during the Omicron epidemic in Japan: A descriptive epidemiological study.","authors":"Yuka Kudo-Nagata, Takahiro Ozawa, Tami Watanabe, Masako Sakurada, Noritaka Sekiya","doi":"10.7883/yoken.JJID.2024.204","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.204","url":null,"abstract":"Updating and evaluating facility-based guidance in cancer centers for managing healthcare personnel (HCP) with close contact with individuals with coronavirus disease 2019 (COVID-19) is challenging because these settings are typically excluded from general guidance, and practical data on this population are limited. This study aimed to describe whether apparent outbreaks occurred under the updated protocol in the real-world setting of a cancer center. From July 2022 to January 2023, 402 HCP who had close contact with an individual with COVID-19 were identified and divided into two groups: the separation group, which underwent a five-day quarantine with physical isolation (172 HCP), and the cohabitation group, which followed a ten-day quarantine (227 HCP). A nucleic acid amplification test (NAAT) was conducted the day before the HCP returned to work. Data from their medical records were retrospectively collected and analyzed. As a primary outcome, no outbreaks due to post-quarantine transmission from close-contacted HCP were observed throughout the study period in either group. Our findings suggested a 5-day quarantine for HCP with close contact with COVID-19 might be applicable in cancer center settings if combined with NAAT before returning to work without increasing the risk of apparent outbreaks.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143537022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Mesocestoides vogae infection in dogs: confusion with echinococcosis.

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-02-28 DOI: 10.7883/yoken.JJID.2024.343

Yasuyuki Morishima, Hiromu Sugiyama

引用次数: 0

Evaluation of rapid amplicon-based nanopore sequencing using the latest chemistry for accurate whole genome analysis of influenza A virus in clinical samples.

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-31 DOI: 10.7883/yoken.JJID.2024.400

Yumani Kuba, Nobuhiro Takemae, Satoshi Kawato, Kunihiro Oba, Kiyosu Taniguchi, Tsutomu Kageyama

{"title":"Evaluation of rapid amplicon-based nanopore sequencing using the latest chemistry for accurate whole genome analysis of influenza A virus in clinical samples.","authors":"Yumani Kuba, Nobuhiro Takemae, Satoshi Kawato, Kunihiro Oba, Kiyosu Taniguchi, Tsutomu Kageyama","doi":"10.7883/yoken.JJID.2024.400","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.400","url":null,"abstract":"MinION sequencing is widely used to sequence influenza A virus (IAV) genomes; however, the accuracy and utility of this approach, using the latest chemistry to obtain whole viral genome sequences directly from clinical samples, remain insufficiently investigated. We evaluated the sequencing accuracy of combining simultaneous multisegment one-step RT-PCR and MinION sequencing using various subtypes of 13 IAV isolates. The latest R10.4.1 chemistry significantly improved sequencing accuracy, achieving ≥99.993% identity with Illumina MiSeq results and reducing the single nucleotide deletion in homopolymer regions. Applying this method to 11 clinical samples enabled rapid subtype identification and the acquisition of eight full-length IAV genomes. In four of these samples, subtype identification of HA and NA was achieved within 20 min after the start of sequencing and a full-length IAV genome was obtained within 7 h after RNA extraction. However, there was concern that cross barcode misassignment during demultiplexing affected data interpretation, particularly for samples with low viral genome copy numbers. This approach can be used for the rapid identification of IAV subtypes and accurate acquisition of full IAV genome sequences from clinical samples, although careful data analysis is required for the multiplex sequencing of clinical samples with low viral genome copy numbers.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Seroprevalence of hepatitis A virus and hepatitis E virus antibodies in Madhesh Province, Dhanusha, Nepal.

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-31 DOI: 10.7883/yoken.JJID.2024.321

Sandesh Rimal, Sabin Shrestha, Aashma Khadka, Mami Matsuda, Ryosuke Suzuki, Shyam Prakash Dumre, Basu Dev Pandey

引用次数: 0

Detection of recombinant type of human adenovirus C composed of type 89 and type 5 in Aichi Prefecture, Japan, 2016-2019.

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-31 DOI: 10.7883/yoken.JJID.2024.246

Emi Hirose, Hiroko Minagawa, Hirokazu Adachi, Masakazu Suzuki, Noriko Nakamura, Noriko Saito, Miyabi Ito, Chikako Mitsuoka, Katsuhiko Sato, Yoshihiro Yasui

{"title":"Detection of recombinant type of human adenovirus C composed of type 89 and type 5 in Aichi Prefecture, Japan, 2016-2019.","authors":"Emi Hirose, Hiroko Minagawa, Hirokazu Adachi, Masakazu Suzuki, Noriko Nakamura, Noriko Saito, Miyabi Ito, Chikako Mitsuoka, Katsuhiko Sato, Yoshihiro Yasui","doi":"10.7883/yoken.JJID.2024.246","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.246","url":null,"abstract":"Recombinant human adenoviruses (HAdVs) have been reported from many countries, including Japan. We report a recombinant HAdV-C type detected in feces with gastroenteritis infection or throat swabs with upper respiratory tract inflammation of six children in Aichi Prefecture. This type may have been prevalent in the area. Between April 2014 and March 2019, we attempted to detect HAdVs in 9,483 specimens (fecal, throat swab, urine, and conjunctival swab) collected from patients with suspected viral infection. A total of 220 HAdV-C isolates were obtained and serotyped by neutralization test (NT). Of these, 62 HAdV-C strains (HAdV-C1: 15, -C2: 19, -C5: 22, -C6: 6) were genotyped by sequencing for the three regions, penton base, hexon, and fiber regions, respectively. All 62 strains were grouped into the same genotype as serotype for the hexon and fiber region. In contrast, phylogenetic analysis showed 6 of the 22 strains with serotype HAdV-C5 were grouped into HAdV-C89 for the penton base region. This type was detected as a recombinant HAdV causing SARI in China between 2017 and 2021, was found to have been persistently detected in transnational Aichi Prefecture over the same period.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Tokyo Metropolitan Government external quality assessment of SARS-CoV-2 nucleic acid amplification tests for clinics in 2023.

IF 1.3 4区医学

Japanese journal of infectious diseases Pub Date : 2025-01-31 DOI: 10.7883/yoken.JJID.2024.205

Rie Moriuchi, Ryouta Inaba, Miyuki Nagano, Mayuko Oda, Takayuki Shinkai, Toshihisa Noguchi, Yoshiyuki Sugishita, Itaru Nishizuka, Yoshikazu Ishii

{"title":"The Tokyo Metropolitan Government external quality assessment of SARS-CoV-2 nucleic acid amplification tests for clinics in 2023.","authors":"Rie Moriuchi, Ryouta Inaba, Miyuki Nagano, Mayuko Oda, Takayuki Shinkai, Toshihisa Noguchi, Yoshiyuki Sugishita, Itaru Nishizuka, Yoshikazu Ishii","doi":"10.7883/yoken.JJID.2024.205","DOIUrl":"https://doi.org/10.7883/yoken.JJID.2024.205","url":null,"abstract":"An external quality assessment (EQA) on nucleic acid amplification tests for SARS-CoV-2 was conducted among clinics that introduced testing instrument through the Tokyo Subsidy Program for Facilities and Equipment for Testing in COVID-19 in 2023. The survey samples consisted of sample 1 (20,000 copies/mL), sample 2 (10,000 copies/mL), and negative sample. Results were obtained through Cycle threshold (Ct) values as well as positive-negative result determinations. On-site technical support was provided to the clinics that responded incorrectly. A total of 544 clinics (589 instruments) participated, and Abbott's ID NOW TM (82.2%) was the most widely used in this survey. The qualitative test results showed high correctness rates, 95.2% for sample 1, 93.2% for sample 2, and 96.3% for negative sample. Differences in Ct values were observed among reagents and instruments. Technical support were provided to 63 clinics. It revealed that discrepancies of qualitative test were mainly due to deviations from the protocol instructions, mixing all three survey samples into one vial and errors caused by foaming. This survey was unique in that the participants were mostly end-users who were not laboratory testing specialists and mainly used point-of-care testing instruments. It is important to continue EQA to improve and maintain testing accuracy.","PeriodicalId":14608,"journal":{"name":"Japanese journal of infectious diseases","volume":" ","pages":""},"PeriodicalIF":1.3,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143079801","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0