Irish Journal of Medical Science最新文献

{"title":"The effect of psychotherapeutic interventions on pain and quality of life in endometriosis: a systematic review and meta-analysis study.","authors":"Handan Özcan, Ayşe Çuvadar, Sevda Uzun","doi":"10.1007/s11845-025-03985-6","DOIUrl":"10.1007/s11845-025-03985-6","url":null,"abstract":"<p><strong>Aim: </strong>This study aimed to determine the effect of psychotherapeutic interventions on pain, quality of life and health profile in women diagnosed with endometriosis.</p><p><strong>Methods: </strong>For this systematic review and meta-analysis study, studies were obtained by searching PubMed, Web of Science, EBSCOhost, Google Scholar, and YÖK Thesis Center databases between August and October 2024 without any year limitation. After the review, 10 studies were included in the study. The data were synthesized by meta-analysis and narrative methods.</p><p><strong>Results: </strong>In this systematic review and meta-analysis, psychotherapeutic interventions for the treatment and management of endometriosis were found to be effective on quality of life (SMD = 0.515, 95% CI = 0.035 to 0.995; Z = 2.104, I² = 67.523%, p < 0.05), pain (SMD =  - 0.454, 95% CI =  - 1.600 to - 0.179; Z =  - 1.566, I² = 84.463, p > 0.05), and health profile (SMD = 0.041, 95% CI =  - 0.363 to 0.281; Z =  - 0.250759, I² = 56.876%, p > 0.05). In subgroup analyses, it was determined that the types of psychotherapeutic interventions were not effective, but the number of sessions was effective.</p><p><strong>Conclusion: </strong>Psychotherapeutic interventions to reduce symptoms in endometriosis are effective in improving quality of life but not pain and health profile.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1391-1400"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413421/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144527987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can artificial intelligence generate scientific discussion that passes peer review for publication in a high-impact orthopaedic journal?","authors":"Gerard A Sheridan, Lisa C Howard, Michael E Neufeld, Tom R Doyle, Andrew J Hughes, Peter K Sculco, David E Beverland, Donald S Garbuz, Bassam A Masri","doi":"10.1007/s11845-025-03971-y","DOIUrl":"10.1007/s11845-025-03971-y","url":null,"abstract":"<p><strong>Background: </strong>There is huge interest in the use of artificial intelligence (AI) in the production and assessment of academic material; however, the role of AI remains unclear.</p><p><strong>Aim: </strong>The purpose of this study was to perform a reviewer-blinded assessment of the quality of scientific discussion generated by an advanced AI language model (ChatGPT-4, Open AI) and determine whether this could be recommended for high-impact journal publication.</p><p><strong>Methods: </strong>The introduction, methods and results sections of a recently published article from a high-impact journal were input into a current AI model. The AI application then produced a discussion and conclusion based on the provided text using a standardized prompt. Six experienced blinded reviewers scored all five sections of the hybrid article. A one-way analysis of variance (ANOVA) was used to assess significant differences between scores of each section. Reviewers recommended a decision regarding the suitability of the article for publication.</p><p><strong>Results: </strong>AI composed a scientific discussion and conclusion. The median score was 80 (IQR 70-90) for introduction, 77.5 (IQR 70-90) for methods, 82.5 (IQR 50-90) for results, 60 (IQR 40-75) for discussion and 60 (IQR 40-80) for the conclusion. The median scores for the AI-generated sections were non-significantly lower than other sections (p = 0.37). The majority of reviewers (5/6, 83%) recommended \"acceptance for publication after major revision\". One reviewer recommended \"resubmission with no guarantee of acceptance\". There were no recommendations for rejection.</p><p><strong>Conclusion: </strong>Current AI large language models are now capable of generating content that passes experienced peer review and is acceptable for publication in a high-impact orthopaedic journal, after revision. There are still many concerns regarding the integration of AI into the process of scientific writing, mainly the tendency of AI to rely on advanced pattern recognition and fabricated or inadequate references.</p><p><strong>Level of evidence: </strong>Level IV.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1191-1198"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413406/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144274871","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal trends in TAVI outcomes: experience from an Irish tertiary referral centre.","authors":"Zaran Butt, Stefan Elekes, Lara Harrington, Laoise Geoghegan, Zsombor Mathe, Julia Rodighiero, Andrew Maree, Mark Hensey, Stephen O'Connor","doi":"10.1007/s11845-025-04001-7","DOIUrl":"10.1007/s11845-025-04001-7","url":null,"abstract":"<p><strong>Background: </strong>Transcatheter aortic valve implantation (TAVI) has become a well-established therapeutic option for severe aortic stenosis in recent decades. There is limited data published about Irish experiences with TAVI.</p><p><strong>Aims: </strong>To characterize contemporary TAVI outcomes from an Irish tertiary referral centre.</p><p><strong>Methods: </strong>A retrospective registry was created which included data on consecutive patients who underwent TAVI in our centre over a 3-year period. The Valve Academic Research Consortium 3 guideline was used to define endpoint definitions.</p><p><strong>Results: </strong>A total of 230 TAVI procedures were performed; 62 (2019), 57 (2020) and 111 (2021). Cumulative mean age was 81 years, with a male majority (65%). Median hospital length-of-stay was lower in 2021 versus 2019 [3 days (IQR 2 to 10) versus 9 days (IQR 4-22), p = 0.008]. Of patients with at least 30-day follow-up data (95.3%), none experienced procedural or 30-day mortality. Cumulative all-cause mortality was 22% over a median follow-up of 491 days (IQR 323 to 780). The incidence of in-hospital cerebro-vascular accidents was higher in 2019 versus 2021 (9.7% versus 1.8%, p = 0.02). A pacemaker was implanted in 20 (9%) cases, while 28 (12%) patients experienced an acute kidney injury. There was a general trend towards temporal improvements in complication rates across the years.</p><p><strong>Conclusions: </strong>The TAVI caseload has risen significantly in our centre in recent years. Overall, peri-procedural complication rates have been low and device success rates high, consistent with international registry data. There have been temporal improvements in the majority of TAVI-related complications and length of hospital stay with increasing operator experience.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1289-1295"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144600392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A qualitative analysis of head and neck cancer patient's lived experience on their treatment journey in a single Irish institution.","authors":"Seamus Boyle, Michael Fitzsimons, Shauna Hurley, Tom Moran, Fergal O'Duffy","doi":"10.1007/s11845-025-04002-6","DOIUrl":"10.1007/s11845-025-04002-6","url":null,"abstract":"<p><strong>Introduction: </strong>Head and neck cancer can have a dramatic impact on the lives of patients. We wish to determine patients subjective preparedness for their treatment and to assess their service satisfaction provided by a Head and Neck Cancer Unit.</p><p><strong>Methods: </strong>An observational cohort study of patients with a diagnosis of head and neck cancer was performed. This consisted of a 22-question survey of post-treatment patients. Patients prior to their clinic appointment were offered a feedback form for completion. The patients were aware that the clinician was blinded to completion of the form and advised that their feedback would not alter their future management.</p><p><strong>Results: </strong>In total, 40 patients completed the questionnaire. Patients felt physically, mentally, nutritionally ready pre-treatment in 94%, 84.2% and 89% respectively. Forty per cent of respondents felt they would have benefited from the support of a psychologist. Regarding speech and swallow, 96% and 93% of patients felt they had adequate education of voice and swallow. 96% felt they had adequate post op support.</p><p><strong>Conclusion: </strong>Patient-reported outcomes and feedback are essential to assess service provision and determine areas of insufficiency. One area of deficiency identified is regarding psychological support and we wish to highlight this insufficiency within our unit.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1401-1404"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144608366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preoperative proteinuria as a novel biomarker for predicting postoperative renal insufficiency after nephrectomy for renal cell carcinoma: a systematic review and meta-analysis.","authors":"Qiankun Xu, Huilan Zheng, Fanchao Zeng, Bin Li, Deliang Huang, Qiang Cai, Zhizhao Yang, Peng Wu","doi":"10.1007/s11845-025-03987-4","DOIUrl":"10.1007/s11845-025-03987-4","url":null,"abstract":"<p><strong>Background: </strong>Identifying reliable predictors of postoperative renal insufficiency (PRI) following partial or radical nephrectomy for renal cell carcinoma (RCC) is critical for optimizing perioperative management.</p><p><strong>Methods: </strong>We systematically searched MEDLINE, Cochrane Library, and Embase up to March 20, 2025, to identify cohort studies that evaluated the association between preoperative proteinuria and PRI. We calculated pooled odds ratios (ORs) with 95% confidence intervals (CIs) using a random-effects model. Subgroup analyses were stratified by study design (prospective vs. retrospective) and surgical modality (partial vs. radical nephrectomy).</p><p><strong>Results: </strong>Six cohort studies involving 3124 patients were included. Preoperative proteinuria was significantly associated with an increased risk of PRI (OR = 2.69, 95% CI 1.48-4.89; I² = 67.3%). We found that retrospective studies showed a stronger association between preoperative proteinuria and PRI (OR = 3.35, 95% CI 1.71-6.56) compared to prospective studies (OR = 1.89, 95% CI 0.98-3.66). Subgroup analysis by surgical approach revealed significant risk elevation in both partial nephrectomy (OR = 2.11, 95% CI 1.34-3.33) and radical nephrectomy cohorts (OR = 5.50, 95% CI 4.31-7.02), with a notably higher effect size in the latter.</p><p><strong>Conclusion: </strong>Preoperative proteinuria is significantly associated with an elevated risk of PRI in patients undergoing nephrectomy for renal cell carcinoma. These findings emphasize the need to incorporate proteinuria assessment into preoperative risk evaluations to improve patient counselling and perioperative management. Future high-quality prospective studies, particularly multicenter investigations with standardized protocols, are essential to confirm these associations and explore the pathophysiological mechanisms underlying proteinuria-related renal functional decline.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1199-1207"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144325696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equestrian-related maxillofacial injuries-a five-year retrospective review.","authors":"Brian Maloney, Min Seo Jung, Gerard Kearns, Conor Bowe","doi":"10.1007/s11845-025-03995-4","DOIUrl":"10.1007/s11845-025-03995-4","url":null,"abstract":"<p><strong>Background: </strong>Equestrian-related activities inherently involve the risk of serious injury. There are few reports of maxillofacial injury patterns and management arising from equestrian activities in the literature.</p><p><strong>Aims: </strong>To investigate maxillofacial fracture presentations at a tertiary trauma centre to identify injury profiles of patients who have sustained equine-based injuries over 5 years.</p><p><strong>Methods: </strong>This work involved a retrospective review of all trauma presentations to our unit over 5 years. The data collected included patient demographics, injury mechanisms and patterns, and management of fractures.</p><p><strong>Results: </strong>The study identified 73 patients with facial fractures resulting from activity with horses between 2020 and 2025. A total of facial fractures were recorded. The mean age was 39.5 (11-86) years. There were 40 (55%) males and 33 (45%) females. Mounted riders accounted for 41% of cases, with 59% being unmounted. The incidence of head injury was 5%. A further 5% had an associated spinal injury. The most common specific mechanism of maxillofacial injury was a direct kick, in 55% of cases. The most commonly affected facial region was the middle third (81%), with zygomaticomaxillary complex fractures most commonly recorded (39%). There was a statistically significant increase in the risk of head injury associated with frontal bone fracture in this group.</p><p><strong>Conclusion: </strong>Activities involving horses pose a high risk of maxillofacial injury. Education should be promoted to increase the usage of helmets with a particular design to protect the facial skeleton, whether mounted or unmounted.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1339-1346"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413334/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Subtype-specific expression of lncRNAs SNHG12 and HAGLR as non-invasive biomarkers for diagnosis and prognosis in breast cancer.","authors":"Mohammad Farid Mohammadi, Arezoo Farhadi, Maedeh Ganji, Morteza Gholami, Yaser Mansoori, Rasoul Abdollahzadeh, Pouria Mohammadi, Javad Behroozi","doi":"10.1007/s11845-025-04011-5","DOIUrl":"10.1007/s11845-025-04011-5","url":null,"abstract":"<p><strong>Background: </strong>Long non-coding RNAs (lncRNAs) SNHG12 and HAGLR have different molecular functions in breast cancer (BC). We investigated their expression profiles in different subtypes of BC, breast tissues, and plasma in association with clinicopathological and reproductive conditions.</p><p><strong>Methods: </strong>The expression levels of SNHG12 and HAGLR were detected by qRT-PCR in 150 BC tumors including 35 triple-negative BC (TNBC), 30 HER2-enriched, 30 luminal B, and 55 luminal A and their corresponding tumor-adjacent apparently normal (TAN), as well as in truly normal (TN) tissues and plasma samples of 150 cancer-free women.</p><p><strong>Results: </strong>The SNHG12 and HAGLR upregulated in tumor tissues compared to TAN and TN, as well as in TAN relative to TN in all subtypes. The increased level of SNHG12 was observed only in TNBC patients with larger tumor sizes and positive status of lymph node metastasis (LNM⁺), while elevated expression of HAGLR was associated with LNM⁺, late grades, and advanced stages of luminal B and A tumors. Regarding the 3-year survival rates, negative associations were found for SNHG12 levels in TNBC and luminal A, as well as for HAGLR in HER2-enriched, luminal B and A patients. The expression of investigated lncRNAs was associated with reproductive factors in breast tissues. The plasma expression showed the importance of SNHG12 and HAGLR as specific diagnostic biomarkers of the TNBC subtype and luminal A or B subtypes, respectively.</p><p><strong>Conclusions: </strong>Our results showed the BC subtype-specific expression profiles of SNHG12 and HAGLR and represent these lncRNAs as useful diagnostic and prognostic biomarkers for BC.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1251-1266"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of vertigo and dizziness in individuals following COVID-19.","authors":"Nur Kesiktaş, Büşra Şirin Ahısha, Funda Çelik, Cansın Medin Ceylan, Tuğba Aydın, Nilgün Erten, Ayşe Karan","doi":"10.1007/s11845-025-04026-y","DOIUrl":"https://doi.org/10.1007/s11845-025-04026-y","url":null,"abstract":"<p><strong>Background: </strong>Coronavirus Disease 2019 (COVID-19) is an infectious disease that affects not only the respiratory system but also the central and peripheral nervous systems. Dizziness, vertigo, and balance problems are among the most frequently reported neurological complaints following COVID-19 infection.</p><p><strong>Aims: </strong>This study aimed to determine the prevalence of dizziness/vertigo in patients who had COVID-19 and to examine the associated risk factors.</p><p><strong>Methods: </strong>This cross-sectional study evaluated 296 patients aged 20-66 years who had recovered from COVID-19. Demographic information and clinical assessment questions related to COVID-19 infection were collected. To assess dizziness/vertigo, the Dizziness Handicap Inventory (DHI) was used to evaluate disability related to dizziness, while the Berg Balance Scale (BBS) was used to assess balance status. All assessments were conducted by the same physician.</p><p><strong>Results: </strong>More than 70% of the participants were female, with a mean age of 46.12 ± 8.21 years. Dizziness/vertigo was present in 25.34% of the 296 patients. Vertigo symptoms were found to be associated with BBS and DHI scores (p < 0.05). Symptoms associated with dizziness/vertigo included a sense of distress, nausea, blurred vision, and tinnitus (p < 0.05). Additionally, 24% of patients reported that their dizziness worsened with stress, while 30.7% stated that it increased with movement.</p><p><strong>Conclusion: </strong>Persistent vertigo symptoms may occur following COVID-19 infection. Given the significant impact of dizziness and balance disturbances on daily life, a multidisciplinary approach involving physical medicine and rehabilitation, neurology, and otolaryngology is essential for comprehensive assessment and management. Identifying risk factors and addressing symptoms early may improve patient outcomes and quality of life.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760020","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening for risk of low energy availability in female Gaelic game athletes in Ireland.","authors":"Aoife Courtney, Adrianne Wyse, Billy Murphy, Elaine McCarthy, Oratile Kgosidialwa, Antoinette Tuthill","doi":"10.1007/s11845-025-04005-3","DOIUrl":"https://doi.org/10.1007/s11845-025-04005-3","url":null,"abstract":"<p><strong>Background: </strong>Low energy availability (LEA), a feature of the female athlete triad (menstrual dysfunction, LEA and decreased bone mineral density), arises when insufficient calories are consumed to support energy expenditure potentially resulting in reproductive, gastrointestinal, cardiovascular, bone health and sports performance compromise.</p><p><strong>Aims: </strong>The aims of this study were to determine the prevalence and awareness of LEA using the Low Energy Availability in Females Questionnaire (LEAF-Q) in female GAA athletes.</p><p><strong>Methods: </strong>Adult female GAA club teams in Ireland were invited to participate in this cross-sectional cohort study. A total of 16 clubs participated in an online survey, which captured LEAF-Q and demographic data.</p><p><strong>Results: </strong>Data was available for 122 athletes; 77 (63%) played Gaelic Football alone, 23 (19%) played Camogie alone and 22 (18%) played both. The median age was 22 years (IQR = 9), mean BMI was 24.55 kg/m² (± 4.94), and mean training duration 5.14 h/week (± 2.67). Forty-seven (38.5%) participants had a LEAF-Q score of ≥ 8 indicating risk of LEA. Younger age and participation in other sports were associated with increased risk of LEA. Forty-two women (34.4%) reported a change in menstruation during intervals of increased exercise intensity. Awareness of LEA and access to multidisciplinary supports were low.</p><p><strong>Conclusions: </strong>The prevalence of increased LEA risk is high in female GAA athletes with poor knowledge of this consequence, emphasising the importance of education, access to resources and prevention and early detection to ensure safe participation for women in these sports.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":""},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144760022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors associated with ST-segment elevation myocardial infarctions among young patients treated in the Mid-West of Ireland: a case series report using secondary data.","authors":"Sandra N Nantumbwe, Roisin Gardiner, Thomas J Kiernan, Niamh M Cummins","doi":"10.1007/s11845-025-03965-w","DOIUrl":"10.1007/s11845-025-03965-w","url":null,"abstract":"<p><strong>Background: </strong>ST-segment elevation myocardial infarction (STEMI) occurs when the myocardium has been damaged due to an acute occlusion of a coronary artery. STEMI commonly presents in older populations; however, little is known about the prevalence and risk factors among young patients. This is the first study on STEMI in young patients in Ireland.</p><p><strong>Aims: </strong>To determine the prevalence of STEMI and explore the associated risk factors in a cohort of young adults aged 45 years and below in the Mid-West of Ireland.</p><p><strong>Methods: </strong>This is a case series report using secondary data analysis of data collected from patients aged 45 years or below, hospitalized at University Hospital Limerick between January 2012 and December 2019. All patients who had a primary diagnosis of STEMI during this time period were eligible for inclusion. Clinical data were collected via electronic records and included demographic, clinical, and biomarker variables.</p><p><strong>Results: </strong>The sociodemographic characteristics of the STEMI patients revealed that a majority were male (90%), overweight or obese (63%), smokers (69%) and lived in urban areas (74%). Over half of the patients (53%) were diagnosed with hypertension, 69% had a family history of cardiovascular disease (CVD) and 40% had diabetes diagnosis. After initial hospitalization, 64% were readmitted for another procedure.</p><p><strong>Conclusions: </strong>This study identified cardiovascular risk factors among STEMI patients in Ireland as male, smoking, family history of cardiovascular disease, and being overweight or obese. This study hopes to increase awareness of young STEMI patients and inform health promotion initiatives within this cohort.</p>","PeriodicalId":14507,"journal":{"name":"Irish Journal of Medical Science","volume":" ","pages":"1267-1277"},"PeriodicalIF":1.6,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413419/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173690","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}