Chemistry - A European Journal最新文献_第8页

Cover Feature: Contrasting Reactions of Carbodiimides With Divalent Lanthanoid Species 封面专题：碳二亚胺与二价类镧的对比反应

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202582803

Vidushi P. Vithana, Zhifang Guo, Glen B. Deacon, Peter C. Junk

引用次数: 0

Chloride Double Perovskites Doped with Sb3+/Er3+ as Stable and Effective Luminescence Materials in the Vis-NIR Region. Sb3+/Er3+掺杂氯离子双钙钛矿作为可见光-近红外区稳定有效的发光材料。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202500066

Inna A Ivashchenko, Volodymyr V Halyan, Lubomir D Gulay, Volodymyr O Yukchymchuk, Andreas Eich, Marin Rusu, Galina Gurieva, Susan Schorr, Paweł Dąbczynski, Yurij Kazarinov, Karina V Lamonova, Oleg Khyzhun, Katarzyna Matras-Postolek

{"title":"Chloride Double Perovskites Doped with Sb3+/Er3+ as Stable and Effective Luminescence Materials in the Vis-NIR Region.","authors":"Inna A Ivashchenko, Volodymyr V Halyan, Lubomir D Gulay, Volodymyr O Yukchymchuk, Andreas Eich, Marin Rusu, Galina Gurieva, Susan Schorr, Paweł Dąbczynski, Yurij Kazarinov, Karina V Lamonova, Oleg Khyzhun, Katarzyna Matras-Postolek","doi":"10.1002/chem.202500066","DOIUrl":"https://doi.org/10.1002/chem.202500066","url":null,"abstract":"The luminescence properties of stable halide double perovskites Cs2BIInCl6, where BI - 40% Ag, 60% Na, doped with Sb3+ and Er3+ in the region 250-1600 nm were investigated for the first time and reveal significant potential for advanced application. We employed XPS and TOF-SIMS for chemical analyses, while SEM, XRD, and Raman Spectroscopy provided insights into the morphology, crystal structure, and vibrational characteristics of the samples. The crystal structures of Cs2Ag0.292Na0.708InCl6, Cs2Ag0.285Na0.715In0.971Er0.029Cl6, Cs2Ag0.16Na0.84In0.893Er0.017Sb0.09Cl6 were examined using single-crystal methods. The excited Sb3+ ions emit blue light at 450 nm due to electronic absorption at sub-band gap levels, facilitating energy transfer to Er3+ ions. Notably, the Er3+ emit radiation at 1540 nm, a wavelength particularly advantageous for optical communication applications. Additionally, emissions at 525 nm, 552 nm, 665 nm and 805 nm are observed, corresponding to f-f transitions of Er3+ ions. These compelling results have been supported by calculations based on Modified Crystal Field Theory, elucidating the effects of varying concentrations of Sb3+ and Er3+ on the crystal structure and luminescent properties. Leveraging the synthesized materials, we successfully have developed a LED prototype that utilizes a UV chip combined with the Cs2Ag0.4Na0.6In0.9Er0.01Sb0.09Cl6 powder as a stable and effective luminophore for optoelectronic applications.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202500066"},"PeriodicalIF":3.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Reducibility-Tunable Carbon Dots for Efficient Radicals Scavenging and Material-Controlled Synthesis. 用于自由基清除和材料控制合成的新型还原性可调碳点。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202500682

Dehui Yang, Yuwei Wang, Pengfei Wang, Chang Sun, Zhenyu Xie, Lizhi Liu, Huiyong Wang, Juan Du, Baozhan Zheng, Yong Guo

{"title":"Novel Reducibility-Tunable Carbon Dots for Efficient Radicals Scavenging and Material-Controlled Synthesis.","authors":"Dehui Yang, Yuwei Wang, Pengfei Wang, Chang Sun, Zhenyu Xie, Lizhi Liu, Huiyong Wang, Juan Du, Baozhan Zheng, Yong Guo","doi":"10.1002/chem.202500682","DOIUrl":"10.1002/chem.202500682","url":null,"abstract":"The development of efficient, nontoxic, and low-cost nano-antioxidants has attracted extensive attention in food preservation but still remains a great challenge in materials design and mechanism exploration. Herein, novel reductive carbon dots (r-CDs) were successfully synthesized via a simple pyrolysis technique using sucrose as the precursor. The experimental results show that r-CDs possess excellent reducibility, and can effectively scavenge a variety of reactive oxygen and nitrogen species (RONS). So, the r-CDs exhibit remarkable preservation effects on apples and strawberries and significantly extend their shelf-life. Mechanistic studies reveal that their outstanding reducibility/antioxidant property is attributed to the formed carbon-core and numerous hydroxyl groups in the pyrolysis process. More interestingly, the reducibility of r-CDs can be gradually regulated by nitrogen doping, the obtained N-doped CDs (N-CDs) can be used to synthesize gold nanomaterial with different morphology and size, proving its potential applications in material-controlled synthesis. This study provides a new idea for the development of non-toxic, efficient carbon nano-antioxidants with tunable reducibility for food preservation and material-controlled synthesis.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202500682"},"PeriodicalIF":3.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Novel Helical Metallocryptand for Size-Selective Recognition of Amino Acid Derivatives with Aliphatic Side Chains. 具有脂肪侧链的氨基酸衍生物尺寸选择性识别的新型螺旋金属密码体。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202501277

Syadza Firdausiah, Ryo Ide, Masahiro Ehara, Pei Zhao, Yoko Sakata, Shigehisa Akine

{"title":"Novel Helical Metallocryptand for Size-Selective Recognition of Amino Acid Derivatives with Aliphatic Side Chains.","authors":"Syadza Firdausiah, Ryo Ide, Masahiro Ehara, Pei Zhao, Yoko Sakata, Shigehisa Akine","doi":"10.1002/chem.202501277","DOIUrl":"https://doi.org/10.1002/chem.202501277","url":null,"abstract":"The novel tris(salen)-type metallocryptand, LNi3, was designed and synthesized. Its crystallographic analysis revealed the presence as a helical enantiomeric pair, right-handed (P) and left-handed (M) forms, rather than the meso-form, which was energetically supported by density functional theory (DFT) calculations. This LNi3 host was capable of recognizing amino acid derivatives by several non-covalent interactions, showing a selectivity to those bearing an aliphatic side chain. Its shape-persistent nature of the cryptand facilitated the size-based discrimination, which was clearly demonstrated by 1H NMR spectroscopic titration studies. Recognition of some of the guests caused the emergence of CD signals, indicating the biased P/M helix inversion equilibrium of LNi3. Three aliphatic side-chain guests, Val, Ile, and Leu, caused an M-favored shifting, while two π-containing side-chain guests, Arg and Trp, showed the preference to the P-form. This metallocryptand, LNi3, overcomes the limitation in recognition of less polar amino acids having an alkyl side chain and provided future applications in molecular recognition, biochemical sensing, and enantiomeric sensing.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202501277"},"PeriodicalIF":3.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Cover Feature: Supergelation via Weak Interactions: An Efficient Method for the Fabrication of Hydrophobic Circularly Polarized Luminescent Materials 弱相互作用下的超凝胶：制备疏水圆极化发光材料的有效方法

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202582802

Arunima Cheran, Anjusha Ranjith, M. Praveen Kumar, Ravi K. Pujala, Jatish Kumar

引用次数: 0

A ketol-acid reductoisomerase inhibitor that has antituberculosis and herbicidal activity. 一种具有抗结核和除草活性的酮酸还原异构酶抑制剂。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202501158

Luke William Guddat, Xin Lin, Julia L Kurz, Yong-Hong Li, Shun Jie Wun, Thierry Lonhienne, Ross P McGeary, Nicholas P West, Gerhard Schenk, Jian-Guo Wang

{"title":"A ketol-acid reductoisomerase inhibitor that has antituberculosis and herbicidal activity.","authors":"Luke William Guddat, Xin Lin, Julia L Kurz, Yong-Hong Li, Shun Jie Wun, Thierry Lonhienne, Ross P McGeary, Nicholas P West, Gerhard Schenk, Jian-Guo Wang","doi":"10.1002/chem.202501158","DOIUrl":"https://doi.org/10.1002/chem.202501158","url":null,"abstract":"Ketol-acid reductoisomerase (KARI) is a target for the development of new biocidal agents. This is based on its essential role in branched chain amino acid biosynthesis in plants and microorganisms, and its absence in animals. The lack of success in developing KARI inhibitors as biocides may be because the inhibitors assessed to date compete directly with the substrate, 2-acetolactate (AL). As a result, effectiveness diminishes when AL accumulates in cells. Furthermore, as these inhibitors are slow binding, an organism could avoid growth slowdown by increasing KARI production. Here, we show a pyrimidinedione, 1f is a competitive but time-dependent inhibitor of AL and NADPH for Mycobacterium tuberculosis (Mt) KARI (Ki = 23.3 nM). A crystal structure of this compound bound to the MtKARI homolog from Staphylococcus aureus (Sa), SaKARI, illustrates this dual competition. In contrast, for Oryza sativa KARI, no time-dependent inhibition by 1f is observed, though it inhibits AL competitively (146 nM) and NADPH uncompetitively. Despite differences in inhibition properties, 1f has an MIC of 12.7 µM for MtH37Rv and inhibits Brassica campestris growth by 63% at 10 mg/mL. Therefore, KARI inhibitors that are competitive for NADPH and show no time dependent inhibition have excellent potential as biocides.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202501158"},"PeriodicalIF":3.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144092164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Affinity-Based Protein Profiling Reveals IDH2 as a Mitochondrial Target of Cannabinol in Receptor-Independent Neuroprotection. 基于亲和的蛋白质分析揭示IDH2是大麻酚在不依赖受体的神经保护中的线粒体靶点。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-19 DOI: 10.1002/chem.202501143

Eva Schaller, Stephanie Lamer, Andreas Schlosser, Christian Stigloher, Pamela Maher, Michael Decker

{"title":"Affinity-Based Protein Profiling Reveals IDH2 as a Mitochondrial Target of Cannabinol in Receptor-Independent Neuroprotection.","authors":"Eva Schaller, Stephanie Lamer, Andreas Schlosser, Christian Stigloher, Pamela Maher, Michael Decker","doi":"10.1002/chem.202501143","DOIUrl":"https://doi.org/10.1002/chem.202501143","url":null,"abstract":"Phytocannabinoids are attracting growing attention because of their potential for treatment of neurodegenerative diseases. Among them, the \"minor\" cannabinoid, cannabinol (CBN), has emerged as a promising neuroprotective agent, acting independently of classical cannabinoid receptors through as-yet unidentified mitochondrial targets. To uncover the molecular basis of its neuroprotective effects, we designed and synthesized a chemical probe based on CBN, incorporating a minimalist diazirine linker. Functional assays confirmed that the probe retains CBN's mitochondrial activity and exhibits strong mitochondrial enrichment, as demonstrated by fluorescence microscopy and click-correlative light and electron microscopy (click-CLEM). By affinity-based protein profiling (AfBPP), we identified isocitrate dehydrogenase 2 (IDH2) as a key mitochondrial target of CBN. This finding was further substantiated by siRNA knockdown studies, which revealed that the absence of IDH2 partially phenocopies CBN's effects, validating its role as a critical mediator of CBN's neuroprotective activity.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202501143"},"PeriodicalIF":3.9,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144101210","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Asymmetric 1,4-Addition and Functionalization Strategy in Total Synthesis. 全合成中的不对称1,4加成和功能化策略。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-16 DOI: 10.1002/chem.202501269

Shaowei Wang, Ping Lu

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Porous Nitrogen-Doped Nb₂C Nanosheets for Electrocatalytic ORR to Selectively Produce H₂O₂. 多孔氮掺杂Nb2C纳米片电催化ORR选择性产H2O2。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-16 DOI: 10.1002/chem.202500758

Meixuan Li, Xinyao Zhang, Bing Ni, Wenbo Yue

{"title":"Porous Nitrogen-Doped Nb2C Nanosheets for Electrocatalytic ORR to Selectively Produce H2O2.","authors":"Meixuan Li, Xinyao Zhang, Bing Ni, Wenbo Yue","doi":"10.1002/chem.202500758","DOIUrl":"10.1002/chem.202500758","url":null,"abstract":"The two-electron pathway in the oxygen reduction reaction (ORR) represents an efficient and environmentally friendly approach for hydrogen peroxide (H2O2) production. Among various types of potential catalysts, MXene have garnered significant attention due to their outstanding electrical conductivity, abundant edge active sites, and low costs. In this study, we successfully synthesize porous N-doped Nb2C nanosheets (N-Nb2C) via a room-temperature ammonia etching method and investigate their ORR performance toward the formation of H2O2. The doping of nitrogen effectively modulates the electronic structure of Nb2C nanosheets, while the abundant surface pores formed during ammonia etching facilitate the ORR process. Hence, the electrocatalytic performance of N-Nb2C nanosheets is significantly improved, demonstrating excellent long-term stability and durability. Notably, in rotating ring-disk electrode (RRDE) tests, the N-Nb2C catalyst achieves a remarkable H2O2 yield of 86.8%, highlighting its potential for selective H2O2 production through electrocatalytic ORR. Our findings suggest that N-doped Nb2C holds great promise for applications in two-electron oxygen reduction for H2O2 synthesis.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202500758"},"PeriodicalIF":3.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Structural Insights and Advanced Spectroscopic Characterization of Thiazolothiazoles: Unveiling Potential for Optoelectronic and Sensing Applications. 结构洞察和先进的光谱表征噻唑噻唑：揭示光电和传感应用的潜力。

IF 3.9 2区化学

Chemistry - A European Journal Pub Date : 2025-05-16 DOI: 10.1002/chem.202501664

Karolina Gutmańska, Agnieszka Podborska, Andrzej Sławek, Ramesh Sivasamy, Lulu Alluhaibi, Alexey Maximenko, Anna Ordyszewska, Konrad Szaciłowski, Anna Dołęga, Tomasz Mazur

{"title":"Structural Insights and Advanced Spectroscopic Characterization of Thiazolothiazoles: Unveiling Potential for Optoelectronic and Sensing Applications.","authors":"Karolina Gutmańska, Agnieszka Podborska, Andrzej Sławek, Ramesh Sivasamy, Lulu Alluhaibi, Alexey Maximenko, Anna Ordyszewska, Konrad Szaciłowski, Anna Dołęga, Tomasz Mazur","doi":"10.1002/chem.202501664","DOIUrl":"https://doi.org/10.1002/chem.202501664","url":null,"abstract":"Thiazolothiazoles (TzTzs) are planar, π-conjugated heterocyclic compounds exhibiting unique structural and optoelectronic properties. In this study, a series of symmetrically substituted TzTz derivatives including imidazolyl, o-vanillyl, p-vanillyl, phenyl, thiazolyl, cinnamoyl, and trifluoromethylphenyl were synthesized and extensively characterized using X-ray crystallography (XRD), Fourier-transformed infrared (FTIR), nuclear magnetic resonance (NMR) and ultraviolet-visible (UV-Vis) spectroscopies, photoluminescence, X-ray absorption near edge structure (XANES, S K-edge), and density functional calculations. The compounds demonstrated diverse intermolecular interactions, including π×××π stacking and chalcogen bonding, which directly influenced their optical properties and electronic band structures. Several derivatives displayed promising features such as large Stokes shifts over 0.4 eV in solution and up to 1 eV in solid state, and reversible resistive switching behavior, positioning them as attractive candidates for use in optoelectronic devices and emerging memristive technologies.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e202501664"},"PeriodicalIF":3.9,"publicationDate":"2025-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144075171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0