Chemistry - A European Journal最新文献_第4页

Breaking the O₂ Activation Bottleneck via Synergistic Electronic Polarization at Adjacent Co-Mn Sites in N-Doped Carbon. 氮掺杂碳中相邻Co-Mn位协同电子极化打破O2活化瓶颈。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-06-25 DOI: 10.1002/chem.71334

Longjie Yu, Bo Liu, Chen Yang, Zigang Zhao, Ziyu Zhang, Bing Liu, Yunkun Dai, Pan Guo, Xiaochun Xu, Wenchao Zhang, Aibing Chen, Lixiao Shen, Yunlong Zhang, Lei Zhao, Zhenbo Wang

{"title":"Breaking the O2 Activation Bottleneck via Synergistic Electronic Polarization at Adjacent Co-Mn Sites in N-Doped Carbon.","authors":"Longjie Yu, Bo Liu, Chen Yang, Zigang Zhao, Ziyu Zhang, Bing Liu, Yunkun Dai, Pan Guo, Xiaochun Xu, Wenchao Zhang, Aibing Chen, Lixiao Shen, Yunlong Zhang, Lei Zhao, Zhenbo Wang","doi":"10.1002/chem.71334","DOIUrl":"10.1002/chem.71334","url":null,"abstract":"Metal-nitrogen-carbon (M-N-C) catalysts with atomically dispersed metal sites have emerged as attractive non-precious alternatives to Pt/C for the oxygen reduction reaction (ORR). Among them, Co-N-C systems have received particular attention because of their favorable stability and low cost, yet isolated Co sites often exhibit insufficient O2 adsorption and charge polarization, limiting further activity enhancement. In this study, we introduce Mn into a Co-N-C matrix via a confined adsorption approach to create adjacent Co-Mn sites. The presence of adjacent Mn electronically modulates the Co center, resulting in a CoMnNC catalyst with markedly improved ORR performance. The catalyst delivers half-wave potential (E1/2) values of 0.80 V in 0.1 M HClO4 and 0.919 V in 0.1 M KOH. Under Zn-air battery testing, its maximum power density reached 193.5 mW cm-2, outperforming Pt/C under identical conditions. Density functional theory (DFT) calculations indicate Mn proximity enriches the electron density at Co and downshifts the Co d-band center. This electronic modulation enhances O2 adsorption and charge polarization, weakens the adsorbed O─O bond and lowers the barrier for OOH* formation. This work clarifies how neighboring metal sites regulate the electronic structure of Co centers to facilitate O2 activation and offers a reference for designing excellent M-N-C catalysts.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e71334"},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148325080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Divergent Total Syntheses of Bisnicalaterine Alkaloids Enabled by a Stereocontrolled Geissoschizol Synthesis. 立体控制的异戊醇合成使双烟碱类生物碱的发散性全合成成为可能。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-06-27 DOI: 10.1002/chem.71328

Sittisak Oekchuae, Satoshi Matsumiya, Kenta Rakumitsu, Mariko Kitajima, Hayato Ishikawa

{"title":"Divergent Total Syntheses of Bisnicalaterine Alkaloids Enabled by a Stereocontrolled Geissoschizol Synthesis.","authors":"Sittisak Oekchuae, Satoshi Matsumiya, Kenta Rakumitsu, Mariko Kitajima, Hayato Ishikawa","doi":"10.1002/chem.71328","DOIUrl":"10.1002/chem.71328","url":null,"abstract":"Bisnicalaterine alkaloids are structurally complex and biologically significant bisindole natural products. Herein, we report the first enantioselective total syntheses of bisnicalaterines B, C, and their N4' epimers using an eight-step longest linear sequence. Central to this strategy is a site- and stereoselective bioinspired Friedel-Crafts-type coupling between the eburnamine and geissoschizol fragment, enabling a highly selective formation of the bisindole core. The geissoschizol framework is efficiently assembled using a stereocontrolled Bischler-Napieralski cyclization/reduction sequence and an organocatalytic enantioselective Michael addition, which establishes the C3 and C15 stereocenters with high fidelity. In addition, the stereochemical relationship between the cis- and trans-fused indoloquinolizidine cores is delineated, offering new insight into conformational control within this alkaloid family. This concise synthetic route not only provides the first laboratory access to these unique natural products but also establishes geissoschizol as a versatile platform for the synthesis of other monoterpenoid indole alkaloids (MIAs) and bisindole alkaloids.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e71328"},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148337085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Photoexcited Nickel(0)-Catalyzed Direct Decarboxylative Cross-Coupling. 光激发镍(0)催化直接脱羧交叉偶联。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-06-27 DOI: 10.1002/chem.71312

Jingsheng Li, Yi Xiao, Xiaoli Shi, Xinyi Liu, Geyang Song, Juan Fan, Dong Xue

引用次数: 0

Front Cover: Lewis Acidity and Anion-Complexation Ability of Oxo- and Phenylimino-Bridged Planar Triphenylboranes as Lithium-Ion-Conducting Solid-State Electrolytes 封面：氧和苯基桥接平面三苯硼烷作为导电锂离子的固态电解质的Lewis酸度和阴离子络合能力

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 DOI: 10.1002/chem.71762

Yuichi Kitamoto, Daiki Tsuji, Shunsuke Yamamoto, Yohei Kitani, Maiko Akiba, Kyota Sampei, Tetsutaro Hattori

引用次数: 0

5′-Carboxy-Nucleoside Decarboxylation for the Synthesis of C-Nucleoside-Amino Acids and Peptides 5'-羧基核苷脱羧合成c -核苷氨基酸和肽。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-07-01 DOI: 10.1002/chem.71325

Xingyue Chen, Junzhi Cao, Prabu Ammasi, Hua-Nan Wang, Yuhua Ge, Gang Chen

{"title":"5′-Carboxy-Nucleoside Decarboxylation for the Synthesis of C-Nucleoside-Amino Acids and Peptides","authors":"Xingyue Chen, Junzhi Cao, Prabu Ammasi, Hua-Nan Wang, Yuhua Ge, Gang Chen","doi":"10.1002/chem.71325","DOIUrl":"10.1002/chem.71325","url":null,"abstract":"<div>\u0000 \u0000 Given the synthetic challenges posed by the labile N-glycosidic bond and diverse nucleobases, which have historically complicated stereochemical control and necessitated protecting-group manipulations in the synthesis of C-nucleoside-amino acid/peptide conjugates, we have developed a general strategy for the efficient synthesis of C-nucleoside–amino acid/peptide conjugates via a photoredox-catalyzed decarboxylative Giese reaction of readily accessible 5′-carboxy-nucleosides. This method tolerates a broad range of nucleoside substrates with unprotected nucleobases and either unprotected or minimally protected sugars, providing C5′-nucleoside-modified alanine building blocks in moderate to good yields and stereoselectivities. Direct C5′ nucleoside modification of peptides was also achieved, affording C5′ nucleoside peptides that resemble nucleoside antibiotics, albeit without any selectivity at the peptide α‑position (C6′). This approach offers a streamlined and modular platform for exploring this novel class of bioactive hybrids.\u0000 </div>","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":"32 38","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis of the Phospha-Wittig Reagent Me3P = P(C2F5) and Generation of a Phospanyl-Wittig Derivative Me3P = C(CF3)P(C2F5)F 磷酸维提格试剂Me3P = P（C2F5）的合成及磷酸维提格衍生物Me3P = C(CF3)P(C2F5)F的生成

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-07-01 DOI: 10.1002/chem.71278

Lukas Hartmann, Hannah Koch, Julia Bader, Beate Neumann, Jan-Hendrik Lamm, Hans-Georg Stammler, Mira Kessler, Berthold Hoge

{"title":"Synthesis of the Phospha-Wittig Reagent Me3P = P(C2F5) and Generation of a Phospanyl-Wittig Derivative Me3P = C(CF3)P(C2F5)F","authors":"Lukas Hartmann, Hannah Koch, Julia Bader, Beate Neumann, Jan-Hendrik Lamm, Hans-Georg Stammler, Mira Kessler, Berthold Hoge","doi":"10.1002/chem.71278","DOIUrl":"10.1002/chem.71278","url":null,"abstract":"In this contribution, we report the synthesis of the diphosphane P2(C2F5)4 and cyclotetraphosphane (PC2F5)4 from the corresponding bromophosphanes P(C2F5)xBr3−x (x = 1, 2). The molecular structure of the cyclotetraphosphane was determined by x-ray diffraction analysis. Subsequent reaction of P2(C2F5)4 with trimethylphosphane (PMe3) afforded the phosphanyl-functionalized phosphorus ylide (Wittig reagent) Me3P = C(CF3)P(C2F5)F, whereas treatment of (PC2F5)4 with PMe3 yielded the base-stabilized phosphinidene Me3P = P(C2F5). The newly obtained species were characterized by multinuclear NMR spectroscopy, and the molecular structures were determined by x-ray diffraction analysis. Me3P = C(CF3)P(C2F5)F as well as Me3P = P(C2F5) represent unique structural motifs that have not been observed within their respective substance class, underlining the remarkable versatility of perfluoroalkyl substituents.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":"32 38","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/chem.71278","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Solvent-Mediated Structural and Luminescence Diversification of Organic Copper(I) Halides 有机卤化铜(I)的溶剂介导结构和发光多样性。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-07-01 DOI: 10.1002/chem.71345

Yuming Sun, Ziqi Yu, Zixian Li, Zhaoyang Hu, Yushuang Li, Qiying Wang, Xiaowu Lei, Lingyan Wang, Zhiwei Chen, Chengyang Yue

{"title":"Solvent-Mediated Structural and Luminescence Diversification of Organic Copper(I) Halides","authors":"Yuming Sun, Ziqi Yu, Zixian Li, Zhaoyang Hu, Yushuang Li, Qiying Wang, Xiaowu Lei, Lingyan Wang, Zhiwei Chen, Chengyang Yue","doi":"10.1002/chem.71345","DOIUrl":"10.1002/chem.71345","url":null,"abstract":"<div>\u0000 \u0000 Low-dimensional organic-inorganic hybrid halides have emerged as a new kind of promising scintillators owing to their high light output and tunable emission across the full visible spectrum. Exploration of new Cu-based halides for x-ray applications has become a current research hotspot. Herein, we performed a solvent-mediated structural design strategy and prepared two new Cu(I)-based halides of (AEMP)4[Cu2Br6]3 and (AEMP)[Cu3Br6]·H2O (AEMP = 1-(2-Aminoethyl)-4-Methyl-Piperazine), in a system. Interestingly, (AEMP)4[Cu2Br6]3 contains 0D [Cu2Br6]4− dimer, while (AEMP)[Cu3Br6]·H2O is composed of 1D [Cu3Br6]3− chain building from corner-shared [Cu3Br6] trimers. In contrast to unstable (AEMP)4[Cu2Br6]3, (AEMP)[Cu3Br6]·H2O exhibits stable and highly efficient photoluminescence and radioluminescence emission with a near-unity photoluminescence quantum yield of 99.45% and a promising radioluminescence light yield of 27,185 photons MeV−1, respectively. Meanwhile, the detection limit of 66.31 nGyair s−1 is much lower than the x-ray dose required for diagnosis (5.5 µGyair s−1). A flexible film with excellent foldability and crack resistance was fabricated for x-ray imaging, which achieves a high spatial resolution of 10 lp mm−1. Combining multiple advantages, including low cost, high luminescence efficiency, and excellent scintillation performance, enable this cuprous halide to stand out as a promising x-ray scintillator.\u0000 </div>","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":"32 38","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148366330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of Screen Printing in Perovskite Solar Devices 丝网印刷在钙钛矿太阳能器件中的应用。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-07-01 DOI: 10.1002/chem.71338

Wenchen Pan, Xinsheng Tang, Xiaodong Hu, Pengju Guo, Shangshang Chen

{"title":"Application of Screen Printing in Perovskite Solar Devices","authors":"Wenchen Pan, Xinsheng Tang, Xiaodong Hu, Pengju Guo, Shangshang Chen","doi":"10.1002/chem.71338","DOIUrl":"10.1002/chem.71338","url":null,"abstract":"<div>\u0000 \u0000 Screen printing, a technology that deposits films in a dotted line connection, plays a pivotal role in advancing the transition of perovskite solar cells (PSCs) from laboratory research to large-scale industrial production for its simple operation and great material conservation. However, the manipulation of perovskite inks remains challenging during screen printing, as the underlying dynamic mechanisms are affected by various factors such as viscosity, solid content, thixotropy, drying time, and rheology, which call for in-depth investigation. Previous research also reveals certain limitations in the devices, including incomplete contact between the perovskite precursor solution and the scaffold, as well as the coffee ring effect. This review provides a comprehensive summary of the application of screen printing in the preparation of charge transport layers, perovskite active layers, and electrodes, which present challenges faced in the field of printed mesoporous PSCs, flexible PSCs, perovskite/c-Si tandem cells, and perovskite solar modules. Furthermore, this review summarizes the overarching trends and presents the emerging insights from the latest research. Finally, it is demonstrated that screen printing exhibits substantial potential for the low-cost fabrication of PSCs, especially when integrated with complementary technologies such as roll-to-roll manufacturing, automated robotic mesh deposition technique, and other relevant processes.\u0000 </div>","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":"32 38","pages":""},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148358604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger-1. 髓系锌指-1经典锌指簇的双重调控功能。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-07-03 DOI: 10.1002/chem.71295

Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee

{"title":"Dual Regulatory Functions of Classical Zinc Finger Clusters from Myeloid Zinc Finger-1.","authors":"Yunha Hwang, Yerim Park, Nohwan Park, Heeju Noh, Hyun Goo Kang, Seung Jae Lee","doi":"10.1002/chem.71295","DOIUrl":"10.1002/chem.71295","url":null,"abstract":"Zinc finger (ZF) proteins constitute a large family of transcriptional regulators that control gene expression through sequence-specific DNA recognition stabilized by Zn2+-coordination. Myeloid zinc finger-1 (MZF1) is a classical ZF protein associated with diverse gene regulation, although the biochemical basis of its promoter recognition remains unclear. MZF1 contains 13 CX2CX12HX3H-type ZF domains organized into two discrete clusters, MZF1(ZF1-4) and MZF1(ZF5-13), suggesting the modular regulation of distinct binding partners. In this study, we investigate the metal-binding properties and promoter recognition behavior of these ZF clusters in MZF1. Spectroscopic studies reveal that MZF1(ZF1-4) exhibits stable Zn2+-coordination with strong resistance to cysteine oxidation, whereas Zn2+ removal from MZF1(ZF5-13) induces rapid oxidation. Fluorescence anisotropy assays show that both ZF clusters of MZF1 bind the promoter sequences of vascular, neuronal, and cancer-related genes, while exhibiting subtle differences in cluster preference. Cerebrovascular gene promoters favor MZF1(ZF5-13), whereas neuronal and cancer-related gene promoters display more variable involvement of the two ZF clusters. These results indicate that MZF1 uses its ZF clusters in a flexible and modular manner, providing a biochemical framework for understanding the differential behavior observed, which could be applied in future studies of MZF1-mediated transcriptional regulation in biological systems.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e71295"},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660485/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148373665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Protein-Independent Liquid-Liquid Phase Separation of Adenosine Triphosphate Under Crowded Conditions. 拥挤条件下三磷酸腺苷不依赖蛋白的液-液相分离。

IF 3.6 2区化学

Chemistry - A European Journal Pub Date : 2026-10-13 Epub Date: 2026-07-03 DOI: 10.1002/chem.71374

Robert Dec, Wojciech Dzwolak, Roland Winter

{"title":"Protein-Independent Liquid-Liquid Phase Separation of Adenosine Triphosphate Under Crowded Conditions.","authors":"Robert Dec, Wojciech Dzwolak, Roland Winter","doi":"10.1002/chem.71374","DOIUrl":"10.1002/chem.71374","url":null,"abstract":"Adenosine triphosphate (ATP), a common constituent of protein-rich biomolecular condensates, itself undergoes liquid-liquid phase separation (LLPS) even in the absence of polypeptides. Using polyethylene glycol as macromolecular crowding agent, we observed robust ATP droplet formation at pH 2-11. Moderate NaCl concentrations and lower temperatures promote LLPS by lowering critical ATP and crowder concentrations. While very high salt reverses this trend, the droplets nevertheless survive in hypersaline environments. We argue that both ion-mediated bridging and anomalous underscreening likely contribute to the response of ATP droplets to increasing ionic strength. Most importantly, physiological millimolar ATP concentrations are sufficient for phase separation in the presence of millimolar Mg2 + and crowders, mimicking intracellular conditions. pH tunes intermolecular interactions, evidenced by inversion of the adenosine circular dichroism (CD) signal. These results reveal intrinsic, protein-independent LLPS of ATP with potential roles in cellular compartmentalization and pathological phase transitions.","PeriodicalId":144,"journal":{"name":"Chemistry - A European Journal","volume":" ","pages":"e71374"},"PeriodicalIF":3.6,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13660498/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148381321","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0