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Regulating Direct-to-Consumer Polygenic Risk Scores 规范直接面向消费者的多基因风险评分
Obstetrical & Gynecological Survey Pub Date : 2024-02-01 DOI: 10.1097/01.ogx.0001008520.24751.6b
Jacob S. Sherkow, Jin K. Park, Christine Y. Lu
{"title":"Regulating Direct-to-Consumer Polygenic Risk Scores","authors":"Jacob S. Sherkow, Jin K. Park, Christine Y. Lu","doi":"10.1097/01.ogx.0001008520.24751.6b","DOIUrl":"https://doi.org/10.1097/01.ogx.0001008520.24751.6b","url":null,"abstract":"(Abstracted from JAMA 2023;330:691–692)\u0000 Polygenic risk scores (PGSs) are genome-wide measurements of an individual's genetic propensities or predispositions, and tests have been recently made more accessible and results more available to consumers. With most genetic tests, a healthcare provider helps consumers to interpret results as they relate to medical conditions, but more and more frequently direct-to-consumer PGSs (DTC-PGS) are unregulated.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"95 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140469536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk for Congenital Anomalies in Children Conceived With Medically Assisted Fertility Treatment 通过医学辅助生育治疗受孕的儿童出现先天性异常的风险
Obstetrical & Gynecological Survey Pub Date : 2024-02-01 DOI: 10.1097/01.ogx.0001008544.02811.12
Christos Venetis, S. Choi, Louisa R Jorm, Xian Zhang, W. Ledger, Kei Lui, A. Havard, Michael Chapman, Robert J. Norman, Georgina M. Chambers
{"title":"Risk for Congenital Anomalies in Children Conceived With Medically Assisted Fertility Treatment","authors":"Christos Venetis, S. Choi, Louisa R Jorm, Xian Zhang, W. Ledger, Kei Lui, A. Havard, Michael Chapman, Robert J. Norman, Georgina M. Chambers","doi":"10.1097/01.ogx.0001008544.02811.12","DOIUrl":"https://doi.org/10.1097/01.ogx.0001008544.02811.12","url":null,"abstract":"(Abstracted from Ann Intern Med 2023;176:1308–1320)\u0000 In the United States, more than 2% of all infants are conceived by assisted reproductive technology (ART). Children born from ART have been shown to have up to 50% increased risk for congenital anomalies (CAs) compared with naturally conceived children.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"801 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140467684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Risk of Endometrial Cancer in Asymptomatic Postmenopausal Women in Relation to Ultrasonographic Endometrial Thickness: Systematic Review and Diagnostic Test Accuracy Meta-analysis 无症状绝经后妇女患子宫内膜癌的风险与超声子宫内膜厚度的关系：系统回顾和诊断测试准确性元分析
Obstetrical & Gynecological Survey Pub Date : 2024-02-01 DOI: 10.1097/01.ogx.0001008532.60946.c3
Salvatore Giovanni Vitale, G. Riemma, S. Haimovich, J. Carugno, L. Pacheco, Tirso Pérez-Medina, John Preston Parry, Péter Török, Jan Tesarik, L. D. Corte, Luigi Cobellis, A. D. S. Sardo, Pasquale De Franciscis
{"title":"Risk of Endometrial Cancer in Asymptomatic Postmenopausal Women in Relation to Ultrasonographic Endometrial Thickness: Systematic Review and Diagnostic Test Accuracy Meta-analysis","authors":"Salvatore Giovanni Vitale, G. Riemma, S. Haimovich, J. Carugno, L. Pacheco, Tirso Pérez-Medina, John Preston Parry, Péter Török, Jan Tesarik, L. D. Corte, Luigi Cobellis, A. D. S. Sardo, Pasquale De Franciscis","doi":"10.1097/01.ogx.0001008532.60946.c3","DOIUrl":"https://doi.org/10.1097/01.ogx.0001008532.60946.c3","url":null,"abstract":"(Abstracted from Am J Obstet Gynecol 2023;228:22–35.e2)\u0000 Endometrial carcinoma (EC) can be suspected in cases of postmenopausal bleeding (PMB) with a thickened endometrium on transvaginal ultrasonography (TVS) examination. Typical guidelines recommend further investigation of PMB when the endometrial lining is greater than 4–5 mm, indicating an elevated risk of EC.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"877 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140467640","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chromosomal, Gestational, and Neonatal Outcomes of Embryos Classified as a Mosaic by Preimplantation Genetic Testing for Aneuploidy 通过植入前非整倍体基因检测被归类为马赛克胚胎的染色体、妊娠和新生儿结果
Obstetrical & Gynecological Survey Pub Date : 2024-02-01 DOI: 10.1097/ogx.0000000000001245
M. Viotti, E. Greco, James A. Grifo, M. Madjunkov, Clifford Librach, M. Çetinkaya, S. Kahraman, Pavel Yakovlev, Nikolay Kornilov, Laura Corti, A. Biricik, E. Cheng, Ching-Ya Su, Maw-Sheng Lee, Michael D. Bonifacio, Amber R. Cooper, Darren K. Griffin, Diane Y. Tran, Purvi Kaur, Frank L. Barnes, C. Zouves, A. Victor, A. Besser, S. Madjunkova, F. Spinella
{"title":"Chromosomal, Gestational, and Neonatal Outcomes of Embryos Classified as a Mosaic by Preimplantation Genetic Testing for Aneuploidy","authors":"M. Viotti, E. Greco, James A. Grifo, M. Madjunkov, Clifford Librach, M. Çetinkaya, S. Kahraman, Pavel Yakovlev, Nikolay Kornilov, Laura Corti, A. Biricik, E. Cheng, Ching-Ya Su, Maw-Sheng Lee, Michael D. Bonifacio, Amber R. Cooper, Darren K. Griffin, Diane Y. Tran, Purvi Kaur, Frank L. Barnes, C. Zouves, A. Victor, A. Besser, S. Madjunkova, F. Spinella","doi":"10.1097/ogx.0000000000001245","DOIUrl":"https://doi.org/10.1097/ogx.0000000000001245","url":null,"abstract":"(Abstracted from Fertil Steril 2023;120(5):957)\u0000 Chromosomal segregation errors during mitosis can result in embryonic mosaicism, a phenomenon where different chromosomal copy numbers exist within a single embryo. Preimplantation genetic testing for aneuploidy (PGT-A) of multicellular biopsies can produce intermediate copy numbers in these cases, where some cells are disomic and some show monosomy or trisomy.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"43 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140465622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prenatal Intravenous Magnesium at 30–34 Weeks' Gestation and Neurodevelopmental Outcomes in Offspring: The MAGENTA Randomized Clinical Trial 妊娠 30-34 周时产前静脉注射镁与后代的神经发育结果：MAGENTA 随机临床试验
Obstetrical & Gynecological Survey Pub Date : 2024-02-01 DOI: 10.1097/01.ogx.0001008516.03549.81
C. Crowther, P. Ashwood, Philippa F. Middleton, Andrew McPhee, Thach Tran, J. E. Harding
{"title":"Prenatal Intravenous Magnesium at 30–34 Weeks' Gestation and Neurodevelopmental Outcomes in Offspring: The MAGENTA Randomized Clinical Trial","authors":"C. Crowther, P. Ashwood, Philippa F. Middleton, Andrew McPhee, Thach Tran, J. E. Harding","doi":"10.1097/01.ogx.0001008516.03549.81","DOIUrl":"https://doi.org/10.1097/01.ogx.0001008516.03549.81","url":null,"abstract":"(Abstracted from JAMA 2023;330(7):603–614)\u0000 Preterm birth is a focus of many studies and interventions but remains the leading cause of global neonatal morbidity and mortality. One particular risk that is elevated in preterm infants is cerebral palsy, which affects movement and/or posture, causing health problems and high health care costs for children and their families.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"32 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140463172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Remote Patient Monitoring for Management of Diabetes Mellitus in Pregnancy Is Associated With Improved Maternal and Neonatal Outcomes 对妊娠期糖尿病患者进行远程监控可改善孕产妇和新生儿的预后
Obstetrical & Gynecological Survey Pub Date : 2023-12-01 DOI: 10.1097/01.ogx.0001004648.97726.34
Agata Kantorowska, Koral Cohen, Maxwell Oberlander, Anna Jaysing, Meredith B. Akerman, A. Wise, Devin M. Mann, Paul A. Testa, Martin R. Chavez, A. Vintzileos, Hye J. Heo
{"title":"Remote Patient Monitoring for Management of Diabetes Mellitus in Pregnancy Is Associated With Improved Maternal and Neonatal Outcomes","authors":"Agata Kantorowska, Koral Cohen, Maxwell Oberlander, Anna Jaysing, Meredith B. Akerman, A. Wise, Devin M. Mann, Paul A. Testa, Martin R. Chavez, A. Vintzileos, Hye J. Heo","doi":"10.1097/01.ogx.0001004648.97726.34","DOIUrl":"https://doi.org/10.1097/01.ogx.0001004648.97726.34","url":null,"abstract":"(Abstracted from Am J Obstet Gynecol 2023;228:726.e1–726.e11)\u0000 Remote patient monitoring (RPM) is a type of telehealth that enables the remote management of patients' health in real time and between office visits. In pregnant patients, studies on the use of telehealth technologies, such as RPM or smartphone-based feedback, to manage diabetes mellitus (DM) have been limited. Some studies have shown that telehealth technologies are not worse than standard management.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"89 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139017676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Management of Endometrial Intraepithelial Neoplasia or Atypical Endometrial Hyperplasia 子宫内膜上皮内瘤变或非典型子宫内膜增生症的治疗
Obstetrical & Gynecological Survey Pub Date : 2023-12-01 DOI: 10.1097/ogx.0000000000001229
Lori Boardman, A. Novetsky, Fidel Valea
{"title":"Management of Endometrial Intraepithelial Neoplasia or Atypical Endometrial Hyperplasia","authors":"Lori Boardman, A. Novetsky, Fidel Valea","doi":"10.1097/ogx.0000000000001229","DOIUrl":"https://doi.org/10.1097/ogx.0000000000001229","url":null,"abstract":"(Abstracted from Obstet Gynecol 2023;142(3))\u0000 Endometrial cancer incidence is rising in the United States and disproportionally affects patients based on race, geography, and socioeconomic status. Endometrial intraepithelial neoplasia (EIN) or atypical endometrial hyperplasia (AEH) is often precursor lesions to adenocarcinoma in the endometrium.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"4 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139023305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Racial Disparities in Hysterectomy Route for Benign Disease: Examining Trends and Perioperative Complications From 2007 to 2018 Using the NSQIP Database 良性疾病子宫切除术路径中的种族差异：使用 NSQIP 数据库研究 2007 年至 2018 年的趋势和围手术期并发症
Obstetrical & Gynecological Survey Pub Date : 2023-12-01 DOI: 10.1097/01.ogx.0001004664.87613.21
Erin T. Carey, K. Moore, A. McClurg, Ayana Degaia, Paul Tyan, Lauren Schiff, Alexis A. Dieter
{"title":"Racial Disparities in Hysterectomy Route for Benign Disease: Examining Trends and Perioperative Complications From 2007 to 2018 Using the NSQIP Database","authors":"Erin T. Carey, K. Moore, A. McClurg, Ayana Degaia, Paul Tyan, Lauren Schiff, Alexis A. Dieter","doi":"10.1097/01.ogx.0001004664.87613.21","DOIUrl":"https://doi.org/10.1097/01.ogx.0001004664.87613.21","url":null,"abstract":"(Abstracted from J Minim Invasive Gynecol 2023;30(8):627–634)\u0000 One of the most common gynecological procedures performed within the United States, the trends of hysterectomy types have changed over the past 30 years, with the 1990s demonstrating predominantly abdominal hysterectomies, whereas current trends tend to favor minimally invasive hysterectomies (MIHs) using laparoscopic or vaginal routes. In addition, within the hysterectomy trend, it is notable that higher rates of abdominal hysterectomy and postoperative complications occur for Black and Hispanic women as seen across varying health care systems.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"54 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139025718","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cervical Cancer Screening: A Review 宫颈癌筛查：综述
Obstetrical & Gynecological Survey Pub Date : 2023-12-01 DOI: 10.1097/01.ogx.0001004660.29812.17
Rebecca B. Perkins, N. Wentzensen, Richard S. Guido, Mark Schiffman
{"title":"Cervical Cancer Screening: A Review","authors":"Rebecca B. Perkins, N. Wentzensen, Richard S. Guido, Mark Schiffman","doi":"10.1097/01.ogx.0001004660.29812.17","DOIUrl":"https://doi.org/10.1097/01.ogx.0001004660.29812.17","url":null,"abstract":"(Abstracted from JAMA 2023;330(6):547–558)\u0000 More than 90% of cervical cancer is caused by persistent infections with carcinogenic human papillomavirus (HPV), leading to precancer and then to cervical cancer. Approximately 100,000 people are treated for cervical precancer, 14,000 people are diagnosed with cervical cancer, and more than 4000 die of cervical cancer in the United States each year.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"610 ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139021988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Diagnostic Yield of Exome Sequencing in Cerebral Palsy and Implications for Genetic Testing Guidelines: A Systematic Review and Meta-analysis 外显子组测序对脑瘫的诊断率及对基因检测指南的影响：系统回顾与元分析
Obstetrical & Gynecological Survey Pub Date : 2023-11-01 DOI: 10.1097/01.ogx.0000996804.54274.a5
P. González-Mantilla, Y. Hu, S. M. Myers, B. M. Finucane, D. H. Ledbetter, C. L. Martin, A. Moreno-De-Luca
{"title":"Diagnostic Yield of Exome Sequencing in Cerebral Palsy and Implications for Genetic Testing Guidelines: A Systematic Review and Meta-analysis","authors":"P. González-Mantilla, Y. Hu, S. M. Myers, B. M. Finucane, D. H. Ledbetter, C. L. Martin, A. Moreno-De-Luca","doi":"10.1097/01.ogx.0000996804.54274.a5","DOIUrl":"https://doi.org/10.1097/01.ogx.0000996804.54274.a5","url":null,"abstract":"(Abstracted from JAMA Pediatr 2023;177(5):472–478) Exome sequencing (ES) is a powerful diagnostic tool that is now used routinely in diagnosing neurodevelopmental disorders, although it is not used as commonly as a tool for the diagnosis of cerebral palsy (CP). Cerebral palsy can and often does occur simultaneously with neurodevelopmental disorders such as intellectual disability (ID), autism spectrum disorder (ASD), and speech disorders, which are often evaluated by ES due to their significant genetic components and the variety of known genes that are associated with each disorder.","PeriodicalId":144618,"journal":{"name":"Obstetrical & Gynecological Survey","volume":"25 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139304544","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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