Regulating Direct-to-Consumer Polygenic Risk Scores

Abstract

(Abstracted from JAMA 2023;330:691–692) Polygenic risk scores (PGSs) are genome-wide measurements of an individual's genetic propensities or predispositions, and tests have been recently made more accessible and results more available to consumers. With most genetic tests, a healthcare provider helps consumers to interpret results as they relate to medical conditions, but more and more frequently direct-to-consumer PGSs (DTC-PGS) are unregulated.