International Wound Journal最新文献

{"title":"Mechanisms and Research Progress of Leech in Diabetic Ulcer Fibrosis","authors":"Yanchun Wang,&nbsp;Xianglong Zheng,&nbsp;Huafa Que,&nbsp;Zhangren Yan","doi":"10.1111/iwj.71013","DOIUrl":"10.1111/iwj.71013","url":null,"abstract":"<p>Delayed wound healing is a major complication of diabetes, with its core pathological process being pathological fibrosis driven by persistent inflammation, metabolic disorders and vascular dysfunction under hyperglycemia. This process involves pathological retention of inflammatory cells, abnormal expression of pro-fibrotic factors, and excessive deposition of extracellular matrix. As a traditional Chinese medicine, leech possesses multiple pharmacological effects including anticoagulation, anti-inflammation and improvement of microcirculation, exerting its therapeutic roles through regulating coagulation, modulating inflammatory responses, and enhancing vascular microcirculation. Simultaneously, leech can reduce epithelial-mesenchymal transition and extracellular matrix deposition by synergistically inhibiting multiple key signalling pathways associated with fibrosis. Future research should focus on elucidating the bioactive components of leech and their synergistic regulatory networks across multiple signalling pathways, providing a theoretical reference for developing leech-based anti-fibrotic drugs.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.71013","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Effectiveness of Continuous Pressure Monitoring Systems for Pressure Ulcer Prevention: A Scoping Review","authors":"Rashedul Hoque,&nbsp;Nicci Aylward-Wotton,&nbsp;Sara Noman,&nbsp;Silvia Caggiari,&nbsp;Joanne Lloyd,&nbsp;Reg Taylor,&nbsp;Caroline Searight,&nbsp;Euan Sadler,&nbsp;Bridie Kent,&nbsp;Rebecca Hardwick,&nbsp;Davide Filingeri,&nbsp;Liudi Jiang,&nbsp;Stephen Duckworth,&nbsp;Peter R. Worsley","doi":"10.1111/iwj.71010","DOIUrl":"10.1111/iwj.71010","url":null,"abstract":"<p>There are many circumstances where individuals with limited mobility are exposed to prolonged postures increasing the risk of pressure ulcers. Technologies have been developed to monitor posture, mobility and pressure exposure; however, their effectiveness in different clinical settings is unknown. The aim of this scoping review was to assess clinical studies using continuous pressure monitoring for the prevention and/or treatment of pressure ulcers. A scoping review of the literature was conducted using the PRISMA-ScR framework. Clinical-based studies were included which used continuous pressure monitoring for assessment and treatment over a minimum of a 2-h period. The outcomes included quantitative measures such as pressure distribution and mobility data, qualitative insights relating to patient comfort and acceptability, and the perceptions of healthcare staff regarding usability and clinical integration of the technology. Twenty-four studies were identified and included in the scoping review, conducted across eight countries spanning three continents. Most studies were undertaken in a hospital setting (67%, <i>n</i> = 16). Following review of the included papers, five core themes were identified: clinical outcomes, pressure metrics, posture and mobility, nurse feedback and patient experience. There was high heterogeneity in study design, outcome measures and different risk of bias limited the scope to synthesise the outcomes. Collectively, the studies indicate that CPM can enhance awareness of interface pressures, support clinical decision-making and inform repositioning strategies for individuals at risk of tissue damage. Reported benefits include greater staff confidence and patient engagement. However, consistent reductions in ulcer incidence have yet to be demonstrated, with larger trials with standardised outcomes required.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.71010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148706439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to ‘Validation of the Swedish Wound-QOL-14: A Shortened Version of the Original 17-Item Wound-Specific Quality of Life Instrument’","authors":"","doi":"10.1111/iwj.71017","DOIUrl":"10.1111/iwj.71017","url":null,"abstract":"<p>\u0000 <span>A. Fagerdahl</span>, “ <span>Validation of the Swedish Wound-QOL-14: A Shortened Version of the Original 17-Item Wound-Specific Quality of Life Instrument</span>,” <i>International Wound Journal</i> <span>23</span>, no. <span>8</span> (<span>2026</span>): e71003, https://doi.org/10.1111/iwj.71003.\u0000 </p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13453428/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148701218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prognostic Markers of Diabetic Foot Ulcer Healing in A Resource-Limited Setting","authors":"Roozbeh Naemi,&nbsp;Zulfiqarali G. Abbas","doi":"10.1111/iwj.71009","DOIUrl":"10.1111/iwj.71009","url":null,"abstract":"<p>This study aimed to identify the prognostic markers for Diabetic Foot Ulcer (DFU) healing using routinely collected clinical data. A prospective cohort study of 1075 (M/F: 664/411) patients who attended the foot clinic with a DFU was conducted. At baseline, detailed clinical data were collected and ulcer characteristics were systematically assessed and classified. During 167 ± 408 days follow-up, ulcers of 1039 patients healed and 36 did not. Ulcers with SINBAD classifications 4, 5 and 6 (compared to SINBAD-3) showed 50%, 60% and 70% increase in the risk of not healing and 2.2, 2.8 and 3.3 folds increase in healing duration respectively. Also, deeper ulcer and having previous ulcer history showed 68% and 47% increase in the risk of ulcer not healing and 57% and 20% increase in healing duration respectively. Each day delay in presentation increased the risk of ulcer not healing by 0.5%. The duration of healing was 2.4 times longer for bigger ulcers (&gt; 1 cm²) and 24% longer in patients with peripheral arterial disease. SINBAD score was the strongest predictor of ulcer healing. Among SINBAD constitutive components, ulcer depth (deep-vs-shallow) was the strongest predictor of risk of ulcer not healing, while ulcer size (bigger-vs-smaller than 1 cm²) was the strongest predictor of ulcer healing duration.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13449175/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148684473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Building Practice Capacity in Skin Health and Wound Management in Canada: A Mixed-Methods Evaluation of Two Education Programs in Home and Community Care","authors":"Janet L. Kuhnke,&nbsp;Mariam Botros,&nbsp;Irmajean Bajnok,&nbsp;Darian T. Cheng,&nbsp;Michelle Rey,&nbsp;Sue Rosenthal,&nbsp;Doris Grinspun","doi":"10.1111/iwj.70999","DOIUrl":"10.1111/iwj.70999","url":null,"abstract":"<p>Hard-to-heal wounds place a major burden on patients and the Canadian health system, underscoring the need to strengthen workforce capacity in skin health and wound management. This mixed-methods program evaluation examined two education programs implemented in Ontario home and community care: one for regulated interprofessional providers and one for personal care providers. Quantitative data were collected through pre-, mid- and post-program surveys, and qualitative data through open-ended survey responses and focus groups. Between 2022 and 2025, 164 regulated providers and 203 personal care providers graduated. Across both programs, participants reported increased confidence in prevention, assessment, treatment, communication, teamwork and application of best practices. Importantly, confidence was interpreted as a proxy indicator for readiness to change practice rather than a stand-alone endpoint. Survey and focus group findings indicated that participants applied learning in practice through earlier identification of skin concerns, more effective escalation and communication with interprofessional colleagues, increased use of best practices and greater attention to prevention. Confidence gains ranged from 30% to over 50% in the regulated-provider program and 20% to 45% in the personal care provider program. Qualitative findings reinforced the impact of increased confidence in practice and included improved prevention focus, communication and changes in practice. Thus, these programs, by increasing confidence and self-reported changes in practice, enhanced learners' capacity to deliver quality skin health and wound care. Practice capacity was operationalised in this study as a multidimensional construct that includes role-appropriate knowledge, confidence, readiness to apply evidence-informed practices, communication and escalation behaviours and participation. These programs offer a scalable model to enhance wound care capacity and support health-system sustainability in Canada. Economic outcomes, while not formally measured in this work, should be examined in future studies, as the findings reflect a promising approach to cutting the cost curve in skin health and wound care.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13445250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148678320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of a You Only Look Once–LabelMe Hybrid AI Model for Automated Assessment of Pressure Injury Size and Pocket","authors":"Kento Ikuta,&nbsp;Kohei Fukuoka,&nbsp;Makoto Nakagaki,&nbsp;Makoto Ohga,&nbsp;Yoshiko Suyama,&nbsp;Haruka Kanayama,&nbsp;Natsuko Fujii,&nbsp;Mamoru Konishi,&nbsp;Hiroyuki Nishikawa,&nbsp;Shunjiro Yagi","doi":"10.1111/iwj.71012","DOIUrl":"10.1111/iwj.71012","url":null,"abstract":"<p>Quantitative assessment of the pressure injury size (S) and pocket (P, undermining) is essential for evaluating wound healing. Conventional LabelMe annotations often lead to oversegmentation, whereas object detection with You Only Look Once (YOLO) enables accurate wound localization. Here, we developed a hybrid AI model that combines LabelMe segmentation with YOLO gating. This single-centre retrospective study compared two models: LabelMe-Seeded Auto-Recognition (LSAR) and YOLO-gated LSAR (YGL). Model performance was evaluated by concordance rate and weighted Cohen's <i>κ</i> for DESIGN-R staging and by mean absolute error (MAE) and median (interquartile range) for area error. Overall, 1017 wound images (training: 979; testing: 38) were analysed. For S, the YGL model achieved higher concordance (85.7%, <i>κ</i> = 0.969) and smaller area errors than did the LSAR. For P, the YGL model demonstrated higher concordance and smaller area errors than did the LSAR model. The YOLO–LabelMe hybrid model improved the stage concordance and size accuracy compared with LabelMe alone. Despite the residual outliers in P assessment, this approach represents a promising step towards automated, clinically adaptable wound measurements.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13439211/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148673893","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe Use of Adrenaline in Cryosurgery for Eyelid Basal Cell Carcinoma Evaluated With Infrared Thermography","authors":"Anna H. C. Wiktorin,&nbsp;Bohman Elin,&nbsp;Johanna V. Berggren,&nbsp;John Albinsson,&nbsp;Sheikh Rafi,&nbsp;Malmsjö Malin","doi":"10.1111/iwj.71005","DOIUrl":"10.1111/iwj.71005","url":null,"abstract":"<p>The efficacy of cryosurgery for skin cancers is believed to depend on thaw time, which may be influenced by the presence of adrenaline in local anaesthetics due to its vasoconstrictive effects. This is the first study to perform detailed, non-invasive temperature measurements using infrared (IR) thermography during cryosurgery for basal cell carcinomas (BCCs), evaluating the impact of adrenaline on thaw time. A total of 15 patients with eyelid BCCs underwent cryosurgery with local anaesthetics both with and without adrenaline. Thawing was continuously monitored using a high-resolution IR camera and compared with the surgeon's visual assessment. No significant difference in thaw time was observed between anaesthetics with and without adrenaline. Thermographic mapping revealed a triphasic thawing curve. The surgeon's visual assessment of thawing corresponded well with the point at which tissue temperatures rose above 0°C, likely indicating the onset of reperfusion, thus providing a clinical margin beyond the actual phase transition. This is the first study to use IR thermography to monitor cryosurgery of BCCs, demonstrating that adrenaline in local anaesthetics does not affect thaw time. The findings suggest that deeper tissue perfusion during BCC treatment may counteract superficial vasoconstriction, supporting the effective use of cryosurgery regardless of adrenaline use.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-08-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13429934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148663755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction to 'Mechanisms and Research Progress of Leech in Diabetic Ulcer Fibrosis'.","authors":"","doi":"10.1111/iwj.71024","DOIUrl":"10.1111/iwj.71024","url":null,"abstract":"","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":"e71024"},"PeriodicalIF":2.2,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13504448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148812841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transforming Inpatient Venous Leg Ulcer Management Through Early Specialist Tissue Viability Intervention","authors":"Fania Pagnamenta,&nbsp;Rebecca Harris,&nbsp;Heather Agar,&nbsp;Catherine Burn","doi":"10.1111/iwj.71006","DOIUrl":"10.1111/iwj.71006","url":null,"abstract":"<p>Inpatient care for venous leg ulcers is often inconsistent, with delays in vascular assessment and compression therapy contributing to prolonged healing and fragmented treatment. This evaluation examined a front-door Tissue Viability Nurse-led service providing specialist assessment at hospital admission. A descriptive service improvement evaluation was conducted. From 2022, patients in the Assessment Ward admitted with leg wounds received Tissue Viability assessment within one working day, including Doppler-based vascular evaluation, wound bed preparation, peri-wound skin optimisation and early initiation of compression therapy. Compression bandaging became a core clinical skill for registered nurses, supported by a rationalised product formulary. This observational evaluation and qualitative review suggested that early specialist involvement supported the timely initiation of compression therapy, reduced variation in inpatient wound care and minimised duplicate referrals through clear Tissue Viability-led care plans. Staff confidence in applying compression was perceived to improve, collaboration with vascular, dermatology and community services strengthened and patients informally reported clearer information and greater continuity of care, supporting a timelier approach to care delivery. Positioning Tissue Viability expertise at the Assessment Ward appeared to support improvements in the consistency and safety of care processes in leg ulcer management. This front-door specialist model, rarely described in acute care literature, enhanced timeliness and coordination and provides a scalable approach to addressing international gaps in acute wound care pathways.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.71006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Validation of the Swedish Wound-QOL-14: A Shortened Version of the Original 17-Item Wound-Specific Quality of Life Instrument","authors":"Ami Fagerdahl","doi":"10.1111/iwj.71003","DOIUrl":"10.1111/iwj.71003","url":null,"abstract":"<p>Health-related quality of life (HRQoL) is increasingly recognized as a key outcome in the management of patients with hard-to-heal wounds. To assess this outcome accurately, valid wound-specific patient-reported outcome measures are required. The Wound-QoL was originally developed as a 17-item questionnaire, and a revised 14-item version, consisting of 14 of the original 17 items, was later introduced to improve clarity and reduce respondent burden. Because changes in item composition may affect psychometric properties, the revised version requires separate evaluation. Therefore, this study aimed to assess the psychometric properties of the Swedish Wound-QoL-14 using data from the Swedish validation study of the Wound-QoL-17. This secondary analysis included data from 88 patients with hard-to-heal wounds recruited from an outpatient wound clinic. Responses from the original instrument were recalculated to reflect the Wound-QoL-14 structure. Internal consistency was assessed using Cronbach's alpha, test–retest reliability using intraclass correlation coefficients, criterion validity by comparison with EQ-5D-3L, responsiveness using standardized response mean, and ceiling and floor effects were examined. The Wound-QoL-14 demonstrated good to excellent internal consistency and test–retest reliability. Criterion validity showed moderate correlations with EQ-5D-3L, responsiveness was moderate for Body and Psyche and smaller for Everyday Life and the global score, and no ceiling or floor effects were observed. The Swedish Wound-QoL-14 is a reliable, valid, and practical instrument for assessing HRQoL in patients with hard-to-heal wounds in clinical practice and research.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 8","pages":""},"PeriodicalIF":2.2,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.71003","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148603084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}