International Wound Journal最新文献

{"title":"Short-term incidence and risk factors of surgical site infection following trauma orthopaedic surgery in Northern Ghana","authors":"Fredrick Gyilbagr,&nbsp;Williams Walana,&nbsp;Ezekiel Kofi Vicar,&nbsp;Jacob Nii Otinkorang Ankrah,&nbsp;Akosua Bonsu Karikari,&nbsp;Oliver Nangkuu Deberu,&nbsp;Mohammed Awal Adam,&nbsp;Mohammed Issah Suglo Bukari,&nbsp;Tolgou Yempabe,&nbsp;John Abanga Alatiiga,&nbsp;Maxwell Kwaku Mensah,&nbsp;Alex Trompeter,&nbsp;Alexis D. B. Buunaaim","doi":"10.1111/iwj.70095","DOIUrl":"https://doi.org/10.1111/iwj.70095","url":null,"abstract":"<p>Trauma and orthopaedic surgery (TOS) can result in surgical site infections (SSIs), and the repercussions include prolonged and increased cost of treatment. This study investigated the incidence and risk factors of SSI following TOS. A prospective cohort study was conducted at the Tamale Teaching Hospital from September 2023 to May 2024. Data on demographics, comorbidities, preoperative, intra-operative and postoperative parameters were collected from patients, medical records and the operation report. SSI was defined following the Centers for Disease Control and Prevention criteria. The incidence of SSI during the study period was determined, and univariate and multivariate logistic regression analyses were used to identify the independent risk factors of SSI. A total of 210 patients were enrolled of which 6.7% (14) developed SSIs, including 1.0% (2) deep and 5.7% (12) superficial SSIs. The incidence of open fractures and closed fractures in this study was 3.3% (7) and 2.9% (6), respectively. According to multivariate regression analysis, blood transfusion before surgery (<i>p</i> = 0.034; OR = 3.53; 1.10–11.33) was identified as an independent risk factor of SSI following TOS. However, there was a significant association between the type of dressing used on the surgical site after surgery (<i>p</i> = 0.035; OR = 4.08; 1.10–15.08) and SSI. The study reported the overall incidence rate of SSI after TOS to be 6.7% (67 per 1000 surgical operations). Blood transfusion before surgery was an independent risk factor of SSI following TOS. Local and global measures that limit the rates of SSI after TOS should be adopted especially in managing high-risk patients such as those who require pre-operative blood transfusion.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70095","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct Sampling Mass Spectrometry Analysis for the Assessment of Wounds: A Systematic Review","authors":"Kanin Pruekprasert,&nbsp;Matthew Tan,&nbsp;Lauren Ford,&nbsp;Alun Huw Davies,&nbsp;Zoltan Takats,&nbsp;Sarah Onida","doi":"10.1111/iwj.70158","DOIUrl":"https://doi.org/10.1111/iwj.70158","url":null,"abstract":"<p>Mass spectrometry is increasingly utilised in medicine to identify and quantify small biomarkers for diagnostic and prognostic purposes. Conventional mass spectrometry, however, requires time-consuming sample preparation, hindering its clinical application. Direct sampling mass spectrometry, which allows for direct analysis of patient samples with minimal preparation, offers potential for clinical use. This systematic review examines the utility of direct sampling mass spectrometry for the assessment of external wounds and explores its translational applications in wound care. Out of 2 930 screened abstracts, six studies were included employing various direct sampling mass spectrometry technologies. These studies focused on burn wounds (<i>n</i> = 3), pressure ulcers (<i>n</i> = 2), and acute surgical wounds (<i>n</i> = 1). Both targeted and untargeted molecular profiling methods were used to examine biomarkers related to inflammatory and healing processes, including various proteins, lipid species, and other metabolites. Direct sampling mass spectrometry was found to complement conventional methods such as histology, providing additional insights into the spatial localisation and accumulation of metabolites within wounds. Additionally, imaging techniques equipped with this technology can spatially map wound surfaces and reveal dynamic changes in wounds as they age or progress through different healing processes, with specific metabolite and protein accumulations potentially aiding in prognostication.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Safety, Tolerability and Efficacy of Cell-Free Amniotic Fluid in the Treatment of Non-Healing Venous Ulcers: Initial Experience From a Prospective, Multicenter, Phase II Study","authors":"Frederick Ditmars,&nbsp;Sarah E. Ducharme,&nbsp;Aliza M. Lee,&nbsp;Jo-Anna Reems,&nbsp;William Samuel Fagg,&nbsp;Jovan N. Markovic","doi":"10.1111/iwj.70171","DOIUrl":"https://doi.org/10.1111/iwj.70171","url":null,"abstract":"<p>Non-healing venous leg ulcers represent a significant healthcare problem that accounts for about $32 billion of spending in the US alone. Consequently, novel treatment strategies represent a major unmet need. The current study (part one of Phase II study [NCT04647240]) assesses the safety, tolerability and efficacy of the use of cell-free human amniotic fluid in treating venous leg ulcers that did not heal following the correction of venous reflux. Patients received cell-free amniotic fluid injections in and around the wound either weekly or biweekly over 12 weeks. Primary outcomes included safety, tolerability and efficacy assessed by complete wound closure, wound area reduction and pain reduction. Eleven patients met enrollment eligibility, and nine completed the study. Five patients achieved complete wound closure by week 12. The average percent reduction in wound area was 83.7%, and pain scores were significantly lower by the study endpoint. No difference was observed in wound healing rates between weekly or biweekly treatment, but bi-weekly treatment was associated with nominally faster recovery. Patients tolerated the treatment, and no side effects were reported. These results indicate that cell-free amniotic fluid injection is a feasible, safe and effective treatment for non-healing venous leg ulcers.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70171","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Epidemiology and the Medical Burden of Diabetic Foot Ulcers Especially in Patients With Infection—A Population-Based Analysis From Germany","authors":"Jürgen Wernecke,&nbsp;Marie Wernecke,&nbsp;Olaf Ebenau,&nbsp;Bastian Spruth,&nbsp;Mareike Krämer,&nbsp;Tobias Vogelmann,&nbsp;York Zöllner","doi":"10.1111/iwj.70157","DOIUrl":"https://doi.org/10.1111/iwj.70157","url":null,"abstract":"<p>Due to limited data on the epidemiology of diabetic foot ulcers (DFU) in Germany, especially for those infected, the study determined the prevalence and incidence of DFU and the associated medical burden. Anonymised claims data of 3.3 million insured lives were sourced from a statutory health insurance fund. Patients with DFU between 04/01/2016 and 12/31/2019 were selected (<i>n</i> = 7764) and divided into patients with/without infection/with prophylactic use of antibiotics. Outcome variables were described categorically. Two-sided <i>t</i>-tests and chi-squared tests (<i>p</i> &lt; 0.05) were performed. The prevalence and incidence in patients with DFU was 4.6% and 2.1%, respectively. The mean Charlson Comorbidity Index was 7.9, significantly higher in those infected than in those uninfected (8.1% vs. 7.2%, <i>p</i> &lt; 0.0001). Amputations occurred significantly more often in DFU patients with infection than in those without (minor 25.4% vs. 3.0%, <i>p</i> &lt; 0.0001; major 6.7% vs. 1.2%, <i>p</i> &lt; 0.0001). The 5-year mortality rate was significantly higher in patients with infection than in those without (64.0% vs. 51.3%, <i>p</i> &lt; 0.0001). The occurrence of comorbidities and complications associated with DFU, in particular the high overall medical burden and mortality rate—especially in DFU patients with infections—underscores the importance of prevention and early, appropriate treatment.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143689762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Effect of Two Different Surgical Modalities for Pelvic Organ Prolapse on Postoperative Wound Infection in Patients: A Meta-Analysis","authors":"","doi":"10.1111/iwj.70410","DOIUrl":"10.1111/iwj.70410","url":null,"abstract":"<p>\u0000 <b>RETRACTION</b>: <span>H. Cui</span>, <span>X. Lang</span>, <span>C. Huang</span>, and <span>J. Sun</span>, “ <span>Effect of Two Different Surgical Modalities for Pelvic Organ Prolapse on Postoperative Wound Infection in Patients: A Meta-Analysis</span>,” <i>International Wound Journal</i> <span>21</span>, no. <span>3</span> (<span>2024</span>): e14802, https://doi.org/10.1111/iwj.14802.\u0000 </p><p>The above article, published online on 12 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley &amp; Sons Ltd. Following an investigation by the publisher, all parties have concluded that this article was accepted solely on the basis of a compromised peer review process. The editors have therefore decided to retract the article. The authors did not respond to our notice regarding the retraction.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70410","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673706","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Effect of Drainage Versus No Drainage after Thyroid Surgery on Wound Complications, a Meta-Analysis","authors":"","doi":"10.1111/iwj.70377","DOIUrl":"10.1111/iwj.70377","url":null,"abstract":"<p>\u0000 <b>RETRACTION:</b> <span>L. Zhang</span>, <span>Y. Wu</span>, <span>X. Liu</span>, <span>J. Han</span>, and <span>J. Zhao</span>, “ <span>Effect of Drainage Versus No Drainage after Thyroid Surgery on Wound Complications, a Meta-Analysis</span>,” <i>International Wound Journal</i> <span>20</span>, no. <span>10</span> (<span>2024</span>): <span>4023</span>–<span>4030</span>, https://doi.org/10.1111/iwj.14291.\u0000 </p><p>The above article, published online on 03 July 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley &amp; Sons Ltd. Following an investigation by the publisher, all parties have concluded that this article was accepted solely on the basis of a compromised peer review process. The editors have therefore decided to retract the article. The authors did not respond to our notice regarding the retraction.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70377","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Effect of Right Anterolateral Thoracotomy Versus Median Sternotomy on Postoperative Wound Tissue Repair in Patients With Congenital Heart Disease: A Meta-Analysis","authors":"","doi":"10.1111/iwj.70382","DOIUrl":"10.1111/iwj.70382","url":null,"abstract":"<p>\u0000 <b>RETRACTION:</b> <span>R. He</span>, <span>K. Zhang</span>, <span>C. Zhou</span>, and <span>C. Pei</span>, “ <span>Effect of Right Anterolateral Thoracotomy Versus Median Sternotomy on Postoperative Wound Tissue Repair in Patients With Congenital Heart Disease: A Meta-Analysis</span>,” <i>International Wound Journal</i> <span>21</span>, no. <span>1</span> (<span>2024</span>): e14343, https://doi.org/10.1111/iwj.14343.\u0000 </p><p>The above article, published online on 28 August 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley &amp; Sons Ltd. Following an investigation by the publisher, all parties have concluded that this article was accepted solely on the basis of a compromised peer review process. The editors have therefore decided to retract the article. The authors did not respond to our notice regarding the retraction.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70382","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Effect of Platelet-Rich Plasma on Healing of Lower Extremity Diabetic Skin Ulcers: A Meta-Analysis","authors":"","doi":"10.1111/iwj.70406","DOIUrl":"10.1111/iwj.70406","url":null,"abstract":"<p>\u0000 <b>RETRACTION:</b> <span>X. Fang</span>, <span>X. Wang</span>, <span>Y. Hou</span>, <span>L. Zhou</span>, <span>Y. Jiang</span>, and <span>X. Wen</span>, “ <span>Effect of Platelet-Rich Plasma on Healing of Lower Extremity Diabetic Skin Ulcers: A Meta-Analysis</span>,” <i>International Wound Journal</i> <span>21</span>, no. <span>4</span> (<span>2024</span>): e14856, https://doi.org/10.1111/iwj.14856.\u0000 </p><p>The above article, published online on 26 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley &amp; Sons Ltd. Following an investigation by the publisher, all parties have concluded that this article was accepted solely on the basis of a compromised peer review process. The editors have therefore decided to retract the article. The authors disagree with the retraction.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70406","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673633","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Impact of Ileostomy on Postoperative Wound Complications in Patients after Laparoscopic Rectal Cancer Surgery: A Meta-Analysis","authors":"","doi":"10.1111/iwj.70394","DOIUrl":"10.1111/iwj.70394","url":null,"abstract":"<p>\u0000 <b>RETRACTION:</b> <span>S. Yang</span>, <span>Y. Lin</span>, <span>W. Zhong</span>, <span>W. Xu</span>, <span>Z. Huang</span>, <span>S. Cai</span>, <span>W. Chen</span>, and <span>B. Zhang</span>, “ <span>Impact of Ileostomy on Postoperative Wound Complications in Patients after Laparoscopic Rectal Cancer Surgery: A Meta-Analysis</span>,” <i>International Wound Journal</i> <span>21</span>, no. <span>3</span> (<span>2024</span>): e14493, https://doi.org/10.1111/iwj.14493.\u0000 </p><p>The above article, published online on 21 November 2023, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley &amp; Sons Ltd. Following an investigation by the publisher, all parties have concluded that this article was accepted solely on the basis of a compromised peer review process. The editors have therefore decided to retract the article. The authors did not respond to our notice regarding the retraction.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70394","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"RETRACTION: Comprehensive Assessment of Risk Factors and Pathogenic Characteristics of Wound Infections Following Thoracoscopic Radical Resection for Lung Cancer","authors":"","doi":"10.1111/iwj.70405","DOIUrl":"10.1111/iwj.70405","url":null,"abstract":"<p>\u0000 <b>RETRACTION:</b> <span>J. Xu</span> and <span>J. Zhu</span>, “ <span>Comprehensive Assessment of Risk Factors and Pathogenic Characteristics of Wound Infections Following Thoracoscopic Radical Resection for Lung Cancer</span>,” <i>International Wound Journal</i> <span>21</span>, no. <span>4</span> (<span>2024</span>): e14830, https://doi.org/10.1111/iwj.14830.\u0000 </p><p>The above article, published online on 26 March 2024, in Wiley Online Library (http://onlinelibrary.wiley.com/), has been retracted by agreement between the journal Editor in Chief, Professor Keith Harding; and John Wiley &amp; Sons Ltd. Following an investigation by the publisher, all parties have concluded that this article was accepted solely on the basis of a compromised peer review process. The editors have therefore decided to retract the article. The authors did not respond to our notice regarding the retraction.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 4","pages":""},"PeriodicalIF":2.6,"publicationDate":"2025-03-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70405","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143673260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}