International Wound Journal最新文献

Revisiting negative pressure wound therapy from a mechanobiological perspective supported by clinical and pathological data

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-18 DOI: 10.1111/iwj.70098

Amit Gefen, Serena Russo, Marino Ciliberti

{"title":"Revisiting negative pressure wound therapy from a mechanobiological perspective supported by clinical and pathological data","authors":"Amit Gefen, Serena Russo, Marino Ciliberti","doi":"10.1111/iwj.70098","DOIUrl":"10.1111/iwj.70098","url":null,"abstract":"Negative pressure wound therapy is used often in the management of surgical incisions, chronic wounds and subacute lesions, and there are numerous publications discussing its clinical application and outcomes. However, whilst clinical use and associated literature have expanded since these systems became commercially available in the 90s, important research and discussion around the mode of action have waned, leading to a deficit in the understanding of how this important therapy influences healing. Further, much research and many publications are predominantly reflective, discussing early theorem, some of which have been proven incorrect, or at least not fully resolved leading to misunderstandings as to how the therapy works, thus potentially denying the clinician the opportunity to optimise use towards improved clinical and economic outcomes. In this narrative review, we discuss established beliefs and challenges to same where appropriate and introduce important new research that addresses the manner in which mechanical strain energy (i.e., deformations) is transferred to tissue and how this influences biological response and healing. In addition, we assess and discuss the effect of different negative pressure dressing formats, how they influence the mode of action and how this understanding can lead to more efficient and effective use and clinical economic outcomes.","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"21 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70098","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142853867","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Application of a minimally invasive full-thickness autologous microcolumn skin harvesting device for donor site tissue collection and augmenting wound healing in a porcine wound model

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-16 DOI: 10.1111/iwj.70094

Stephen Smith, Brenda Curtis, Lisa Nicholson, Thomas Koshy, Tyler Max, Brian Prevish, Madeleine Goedegebuure, Gregory Manista, Joshua Tam

{"title":"Application of a minimally invasive full-thickness autologous microcolumn skin harvesting device for donor site tissue collection and augmenting wound healing in a porcine wound model","authors":"Stephen Smith, Brenda Curtis, Lisa Nicholson, Thomas Koshy, Tyler Max, Brian Prevish, Madeleine Goedegebuure, Gregory Manista, Joshua Tam","doi":"10.1111/iwj.70094","DOIUrl":"10.1111/iwj.70094","url":null,"abstract":"Using a 6-week porcine full-thickness excisional wound grafting model, we evaluated the Autologous Regeneration of Tissue (ART®) System, a novel skin harvesting device designed to collect autologous full-thickness autologous microcolumns (FTAM) at 0.5 mm in diameter. The donor skin sites were harvested using the ART® System and compared to split-thickness skin grafts (STSGs). Recipient sites were divided into three treatment groups: FTAM, STSG and Untreated control. Comparing the FTAM donor sites to the STSG donor sites, we observed significantly faster re-epithelization by Day 4 (p < 0.05), earlier adnexal structures and rete ridge formation by Week 3, and increased collagen and elastin content by Week 6. We also observed an increased rate of healing at the FTAM donor site whilst limiting donor site morbidity compared to traditional STSG donor sites. Time to recipient site closure was 2.4 weeks for STSG treated, 3.3 weeks for FTAM treated and 4.1 weeks for the Untreated control (p < 0.05). The STSG and FTAM recipient sites reached complete re-epithelialization by Weeks 4 and 5, respectively which was significantly faster compared to the Untreated control. However, the FTAM recipient site received only 10% of the donor site tissue relative to the recipient site area and the amount of donor site tissue grafted on the STSG recipient sites was 5× more than the FTAM recipient sites. Additionally, the FTAMs harvested by the ART® System augmented recipient wound site healing as a result of ‘epithelial island’ expansion in contrast to Untreated control sites that closed primarily by contracture.","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"21 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70094","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical performance and cost-effectiveness of a Silicone foam with 3DFit™ technology in chronic wounds compared with standard of care: An open randomised multicentre investigation

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-16 DOI: 10.1111/iwj.70074

David Voegeli, Malene Hornbak Landauro, Trine Sperup, Nayla Ayoub, John William McRobert

{"title":"Clinical performance and cost-effectiveness of a Silicone foam with 3DFit™ technology in chronic wounds compared with standard of care: An open randomised multicentre investigation","authors":"David Voegeli, Malene Hornbak Landauro, Trine Sperup, Nayla Ayoub, John William McRobert","doi":"10.1111/iwj.70074","DOIUrl":"10.1111/iwj.70074","url":null,"abstract":"The objective of the study was to show the clinical performance and cost-effectiveness of a Silicone foam dressing with 3DFit™ Technology compared to current standard of care. This was an open-labelled, two-arm, randomised controlled multicentre study conducted from February to December 2023. One hundred and two participants with an exuding, non-infected and chronic ulcer were randomised in a 1:1 fashion and treated with either a Silicone foam with 3DFit™ Technology or standard of care (a filler combined with a secondary dressing), stratified by venous leg ulcers and diabetic foot ulcers. After a 4-week study period, wound size and total costs were evaluated. After 4 weeks of treatment, a comparable percentage in wound area reduction was observed in both treatment arms with mean and 95% confidence interval of 54.3% (37.1%; 71.5%) and 43.0% (26.5%; 59.6%) for the investigational and comparator dressing, respectively. This corresponded to a mean difference of 11.3% ([−10.22; 32.86], p = 0.299). Total mean estimated costs were significantly lower for the investigational dressing (£14.3, 95% confidence interval [£9.6; £19.0]) compared to the two-dressing regime (£21.4 [£16.9; £26.0]), corresponding to a 33% price reduction (p = 0.033) after 4 weeks of treatment. With this RCT, a conforming Silicone foam dressing with 3DFit™ Technology was shown to be clinically comparable and a cost-effective alternative to using a filler and a secondary dressing at a significantly lower cost in both venous leg ulcers and diabetic foot ulcers up to 2 cm in depth.","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"21 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70074","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142836631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Effects of Application of the Clinical Nursing Pathway on Surgical Site Wound Infection and Postoperative Complication Rates in Patients with Total Knee Arthroplasty: A Meta-Analysis 回放：临床护理路径的应用对全膝关节置换术患者手术部位伤口感染和术后并发症发生率的影响：一项 Meta 分析。

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70168

引用次数: 0

RETRACTION: Influences of Evidence-Based Nursing Intervention on Pressure Ulcers in Intensive Care Units: A Meta-Analysis 返回：循证护理干预对重症监护病房压疮的影响：一项 Meta 分析。

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70162

引用次数: 0

Influence of skin hydration level on the occurrence of blisters on the foot during hiking 皮肤水分含量对徒步旅行中脚部起泡的影响。

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70024

Alba Gracia-Sánchez, Alfonso Martínez-Nova, Coral Moya-Cuenca, Sara Zúnica-García, Esther Chicharro-Luna

{"title":"Influence of skin hydration level on the occurrence of blisters on the foot during hiking","authors":"Alba Gracia-Sánchez, Alfonso Martínez-Nova, Coral Moya-Cuenca, Sara Zúnica-García, Esther Chicharro-Luna","doi":"10.1111/iwj.70024","DOIUrl":"10.1111/iwj.70024","url":null,"abstract":"Friction blisters are common among outdoor enthusiasts, yet their causes remain uncertain. This study aimed to compare foot hydration in long-distance hikers with and without blisters, and to assess variability based on age and sex. An observational case–control study involving 86 hikers was conducted. Skin hydration was measured using a corneometer on various foot zones. Data on blister count, footwear, sex, age, and temperature were recorded. The most hydrated zones were the digital area, forefoot, and heel. Higher hydration was found in the blister group (61.6%) compared to the control group (38.4%). A significant relationship between hydration and blisters was observed in the left foot (p = 0.032). Total foot hydration was higher in women (p = 0.007) and inversely related to age (r = −0.333; p = 0.002). Hydration values above 30.40 a.u. in the right foot and 27.37 a.u. in the left foot were linked to blisters with 80% sensitivity. This study highlights the variability in foot hydration and its relationship with blisters. The influence of age and wet socks underscores the complexity of blister formation, emphasizing the need for future research on effective prevention.","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"21 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70024","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828314","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Meta-Analysis Comparing Different Ultrasound Detection Methods to Accurately Assess Wound Healing and Scar Formation after Caesarean Section 返回：比较不同超声检测方法以准确评估剖腹产术后伤口愈合和疤痕形成的 Meta 分析。

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70161

引用次数: 0

Implementation of the REPRISE care bundle model for the prevention of pressure ulcers in an intensive care unit: An experimental study 在重症监护病房实施 REPRISE 护理捆绑模式以预防压疮：一项实验研究。

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70138

Zeynep Cor, Ganime Esra Soysal

{"title":"Implementation of the REPRISE care bundle model for the prevention of pressure ulcers in an intensive care unit: An experimental study","authors":"Zeynep Cor, Ganime Esra Soysal","doi":"10.1111/iwj.70138","DOIUrl":"10.1111/iwj.70138","url":null,"abstract":"The aim of this study was to evaluate the effectiveness of the REPRISE care bundle (CB) model for pressure ulcer (PU) prevention in intensive care patients and to determine the impact of the training provided to nurses on their knowledge base and attitudes. This study has an experimental design. The study was conducted in the anaesthesia and resuscitation intensive care unit on a total of 72 patients. The prevalence of PU was compared between the control group and the REPRISE-CB group. For the nurses, 50 nurses working in the ICU were included in the study. The nurses' knowledge and attitudes towards PU were compared before and after the training. The data were analysed using a statistical program. The incidence of IW was significantly lower in the intervention group (13.9%) compared to the control group (38.9%) (p < 0.05). The study showed that oedema, low albumin levels, low mean blood pressure and low Braden Scale scores were significant risk factors for the development of PU. In addition, the training provided to nurses was found to significantly improve their knowledge and attitudes (p < 0.05). It was concluded that REPRISE-CB was effective in the prevention of PU and that nurses' knowledge increased with training.","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"21 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70138","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828359","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

RETRACTION: Effects of Negative-Pressure Wound Therapy in the Prevention of Surgical-Site Wound Infection After Vascular Surgery: A Meta-Analysis

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70169

引用次数: 0

Epidemiological and clinical characteristics of severe burns in adults: A retrospective study at a burn centre in Suzhou, China 成人严重烧伤的流行病学和临床特征：中国苏州烧伤中心的回顾性研究。

IF 2.6 3区医学

International Wound Journal Pub Date : 2024-12-15 DOI: 10.1111/iwj.70097

Yong Zhang, Jiandong Su, Yunfeng Liu, Ran Sun, Ruizhu Sun

{"title":"Epidemiological and clinical characteristics of severe burns in adults: A retrospective study at a burn centre in Suzhou, China","authors":"Yong Zhang, Jiandong Su, Yunfeng Liu, Ran Sun, Ruizhu Sun","doi":"10.1111/iwj.70097","DOIUrl":"10.1111/iwj.70097","url":null,"abstract":"Severe burns lead to malformations and higher mortality and have long-term social consequences. We aimed to analyse the epidemiologic characteristics and clinical outcomes of severe burn patients hospitalized in a major burn centre in Eastern China. This study included severe burns patients hospitalized in our hospital from 2017 to 2022. We extracted all data from electronic medical records for retrospective analysis. Burn scoring systems were calculated for all patients. The median age of the patients was 49.00 years, with 62.13% of them aged between 30 and 59 years. Of the 375 adult patients, 256 were male and 119 were female. The major cause of burns was flame (46.1%), followed by explosion (35.2%). The median total body surface area was 40%. Sixty-three percent of patients suffered an inhalation injury and 125 patients (33.3%) developed complications during hospitalization. The average mortality was 5.3%. Higher mortality rates are associated with advanced age, flame burns, larger full-thickness burns area and total body surface area, inhalation injuries and combined burn complications. Severe burns often occur in middle-aged men. Governments and companies need to improve the safety of living and working environments. It is essential to develop treatment strategies based on risk factors for burn deaths and improve the quality of medical care.","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"21 12","pages":""},"PeriodicalIF":2.6,"publicationDate":"2024-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70097","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0