International Wound Journal最新文献

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Pooled, Frozen, Gamma-Irradiated Amniotic Fluid Enhances Histomorphological Remodelling in Hypertrophic Scars 汇集、冷冻、γ辐照羊水促进肥厚性瘢痕的组织形态学重塑。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-10-08 DOI: 10.1111/iwj.70753
Gamze Tumentemur, Elif Ganime Aygun, Bulut Yurtsever, Ercument Ovali
{"title":"Pooled, Frozen, Gamma-Irradiated Amniotic Fluid Enhances Histomorphological Remodelling in Hypertrophic Scars","authors":"Gamze Tumentemur,&nbsp;Elif Ganime Aygun,&nbsp;Bulut Yurtsever,&nbsp;Ercument Ovali","doi":"10.1111/iwj.70753","DOIUrl":"10.1111/iwj.70753","url":null,"abstract":"<p>Hypertrophic scars (HTSs) result from excessive collagen accumulation and impaired wound remodelling, leading to considerable aesthetic and functional concerns. Despite the availability of various treatment strategies, their clinical success remains limited, emphasising the need for alternative approaches. Human amniotic fluid (hAF), naturally enriched with cytokines and growth factors, has emerged as a promising biological material for tissue regeneration. This study investigated the therapeutic potential of two forms of hAF—pooled-frozen and pooled-frozen gamma-irradiated—in a rat model of hypertrophic scarring. Fifteen adult male Sprague–Dawley rats were randomly assigned to receive subcutaneous injections of either saline, pooled-frozen hAF, or pooled-frozen gamma-irradiated hAF at the wound margins on days 1, 3 and 5 following the induction of hypertrophic scars via talc powder application. After 21 days, wound healing was evaluated through histological and immunohistochemical analyses. Both treatment groups demonstrated significantly improved wound healing compared to the control group. Granulation tissue formation was enhanced in the treated groups, particularly in animals receiving gamma-irradiated fluid, which also showed superior collagen remodelling characterised by aligned and mature collagen bundles. Both treatment groups demonstrated an increase in M2 macrophage density, as evidenced by elevated Arg<sup>+</sup>/CD68<sup>+</sup> cell ratios; however, this effect was more pronounced in the gamma-irradiated group, indicating a stronger shift towards a regenerative immune profile. Enhanced reepithelialisation, increased hair follicle density and reduced scar thickness were also observed. These findings suggest that gamma-irradiated hAF provides a more effective and minimally invasive therapeutic option for modulating scar formation and improving wound healing outcomes, supporting its potential translation into clinical applications for the management of hypertrophic scars.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12504796/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145244579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Closed-Incision Negative Pressure Therapy: Scoping Review and Multidisciplinary Consensus Recommendations of the Spanish Observatory of Infection in Surgery 封闭切口负压治疗:西班牙手术感染观察站的范围审查和多学科共识建议。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-10-06 DOI: 10.1111/iwj.70750
Josep M. Badia, Inés Rubio-Pérez, Carlos Morales-Pérez, José Bueno-Lledó, Laura M. Rodríguez-Lorenzo, Joan Sancho, Oliver Marín-Peña, Susana López, Jaume Masià, José M. Balibrea
{"title":"Closed-Incision Negative Pressure Therapy: Scoping Review and Multidisciplinary Consensus Recommendations of the Spanish Observatory of Infection in Surgery","authors":"Josep M. Badia,&nbsp;Inés Rubio-Pérez,&nbsp;Carlos Morales-Pérez,&nbsp;José Bueno-Lledó,&nbsp;Laura M. Rodríguez-Lorenzo,&nbsp;Joan Sancho,&nbsp;Oliver Marín-Peña,&nbsp;Susana López,&nbsp;Jaume Masià,&nbsp;José M. Balibrea","doi":"10.1111/iwj.70750","DOIUrl":"10.1111/iwj.70750","url":null,"abstract":"<p>Surgical site infections (SSI) and surgical site complications (SSC) significantly impact surgery outcomes, increasing hospital stays and mortality rates, and negatively affecting patients' quality of life. Closed-incision negative pressure therapy (ciNPT) emerged as a prophylactic strategy to reduce these complications. However, its applicability across different surgical procedures remains unclear. A scoping review was conducted to synthesise the available evidence on the use of ciNPT in different surgical contexts. A multidisciplinary panel of experts from different surgical specialties was assembled to identify patient risk factors for SSCs specific to each modality. Surgical procedures were categorised based on anticipated SSC rates and the impact of SSI. A decision diagram was finally developed, providing tailored recommendations for ciNPT use according to individual surgical circumstances. The findings of the review indicate that ciNPT effectively reduces SSI and SSC in most surgical procedures. Key patient-related factors influencing outcomes, such as age, obesity, and malnutrition, were outlined. Additionally, a specialty-based list of surgical procedures was compiled, specifying whether ciNPT is recommended, not recommended, or conditionally recommended based on specific criteria. This study underscores the benefits of ciNPT and provides a comprehensive guide to its application across several surgical specialties, aiming to optimise patient management and inform clinical practise.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12501416/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145238587","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction to “Predictive Value of Clinical and Demographic Variables in Martorell Ulcers: An Analysis Based on Case Reports” 更正“临床和人口学变量对马托雷尔溃疡的预测价值:基于病例报告的分析”。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-10-01 DOI: 10.1111/iwj.70768
{"title":"Correction to “Predictive Value of Clinical and Demographic Variables in Martorell Ulcers: An Analysis Based on Case Reports”","authors":"","doi":"10.1111/iwj.70768","DOIUrl":"10.1111/iwj.70768","url":null,"abstract":"<p>F. I. de la Rosa-Negrón, M. Á. Castaño-López, and F. Navarro-Roldán, “Predictive Value of Clinical and Demographic Variables in Martorell Ulcers: An Analysis Based on Case Reports” <i>International Wound Journal</i> 22, no. 8 (2025): e70721, https://doi.org/10.1111/iwj.70721.</p><p>The epidemiological data at the end of the first paragraph of the Introduction is supported by reference no. 21 (Liroz-Imaz A., García-Montero A., Gombau-Baldrich Y., and Guinot-Bachero J., “Martorell Hypertensive Ischemic Ulcer: A Pain Perspective Approach,” <i>Gerokomos</i> 33, 3 (2022): 146–151).</p><p>During the implementation of the corrections suggested by the reviewers, this citation was inadvertently omitted.</p><p>We apologize for this error.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70768","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145206554","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Human Placenta-Derived Cells (PDA-002) in Diabetic Foot Ulcer Patients With and Without Peripheral Artery Disease: A Phase 2 Multi-Center, Randomised, Double-Blind, Placebo-Controlled Trial. 人胎盘来源细胞(PDA-002)在伴有或不伴有外周动脉疾病的糖尿病足溃疡患者中的应用:一项多中心、随机、双盲、安慰剂对照试验
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-10-01 DOI: 10.1111/iwj.70769
Richard Pollak, James Anderson, Bert Altmanshofer, Joseph Caporusso, Gary Fantini, Sharmila Koppisetti, Stephen Brigido, Robert Hariri
{"title":"Human Placenta-Derived Cells (PDA-002) in Diabetic Foot Ulcer Patients With and Without Peripheral Artery Disease: A Phase 2 Multi-Center, Randomised, Double-Blind, Placebo-Controlled Trial.","authors":"Richard Pollak, James Anderson, Bert Altmanshofer, Joseph Caporusso, Gary Fantini, Sharmila Koppisetti, Stephen Brigido, Robert Hariri","doi":"10.1111/iwj.70769","DOIUrl":"https://doi.org/10.1111/iwj.70769","url":null,"abstract":"<p><p>The management of diabetic foot ulcers in patients with peripheral artery disease remains challenging. Human placenta-derived cells (PDA-002), a mesenchymal stromal cell-like population obtained from full-term placental tissue, possess angiogenic and tissue regenerative properties. Participants were stratified based on peripheral artery disease status. A total of 159 individuals were randomly assigned to receive intramuscular PDA-002 at one of three doses (3 × 10<sup>6</sup>, 10 × 10<sup>6</sup> and 30 × 10<sup>6</sup> cells) or a placebo. This Phase 2 multi-center, randomised, double-blind, placebo-controlled trial evaluated adults with chronic diabetic foot ulcers with and without peripheral artery disease. The primary efficacy endpoint was the proportion of participants achieving complete wound closure of the index ulcer within 3 months, with sustained closure maintained for an additional 4 weeks. PDA-002 was well-tolerated, with no treatment-related serious adverse events. Intramuscular PDA-002 treatment achieved the highest efficacy at the 3 × 10<sup>6</sup> cell dose within the peripheral artery disease subgroup (38.5% vs. 22.6% for placebo), meeting a stringent 4-week durability endpoint that surpassed the U.S. Food and Drug Administration's recommended 2-week sustainability criterion. PDA-002 shows promise as a breakthrough treatment for diabetic foot ulcers and peripheral artery disease, demonstrating efficacy with two intramuscular doses and no re-treatment. Trial Registration: ClinicalTrials.gov identifier: NCT # 02264288.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":"e70769"},"PeriodicalIF":2.5,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145280196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Protective Efficacy of a New Soft Silicone Multi-Layer Dressing in Reducing the Heel Pressure Ulcer Risk 新型软性硅胶多层敷料对降低足跟压性溃疡风险的保护作用。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-09-30 DOI: 10.1111/iwj.70764
Daria Orlova, Aleksei Orlov, Amit Gefen
{"title":"The Protective Efficacy of a New Soft Silicone Multi-Layer Dressing in Reducing the Heel Pressure Ulcer Risk","authors":"Daria Orlova,&nbsp;Aleksei Orlov,&nbsp;Amit Gefen","doi":"10.1111/iwj.70764","DOIUrl":"10.1111/iwj.70764","url":null,"abstract":"<p>Soft silicone multi-layer dressings are commonly used for pressure ulcer (pressure injury) prevention, yet their effectiveness varies based on design, construct, and material properties. This study evaluated the protective efficacy of a new multi-layer dressing, ALLEVYN COMPLETE CARE (ACC, Smith &amp; Nephew Limited), which incorporates an advanced structure facilitating the dissipation of shear forces through internal layer-on-layer frictional sliding within the dressing. Using a combination of experimental frictional energy absorber effectiveness (FEAE) testing and computational finite element modelling, we quantified the capacity of this dressing to mitigate strain and stress concentrations in the soft tissues of the supported posterior heel. The dressing demonstrated considerable frictional sliding between its adjacent layers, resulting in FEAE = 93% under simulated, clinically relevant usage conditions. This was associated with the dissipation of shear forces and alleviation of strain/stress concentrations in the skin and underlying soft tissues below the dressing. The dressing completely eliminated the stress and strain peaks at the top quartiles of the strain/stress domain (with reference to a no-dressing case). This work provided valuable insights into advanced testing methods and beneficial design principles for pressure ulcer prevention dressings. Earlier investigations concluded that a previous-generation ALLEVYN LIFE dressing achieved high levels of FEAE and thus provided protection. Our findings here establish that the next-generation dressing, ACC, demonstrates even greater protective capacity.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12483953/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145199307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Borate-Based Bioactive Glass Advances Wound Healing in Non-Healing Wagner Grade 1 Diabetic Foot Ulcers: A Randomised Controlled Clinical Trial 基于硼酸盐的生物活性玻璃促进未愈合的瓦格纳1级糖尿病足溃疡的伤口愈合:一项随机对照临床试验
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-09-27 DOI: 10.1111/iwj.70763
David G. Armstrong, Dennis P. Orgill, Robert D. Galiano, John Lantis, Paul M. Glat, Marcus Gitterle, Marissa J. Carter, Nathan Young, Charles M. Zelen
{"title":"A Borate-Based Bioactive Glass Advances Wound Healing in Non-Healing Wagner Grade 1 Diabetic Foot Ulcers: A Randomised Controlled Clinical Trial","authors":"David G. Armstrong,&nbsp;Dennis P. Orgill,&nbsp;Robert D. Galiano,&nbsp;John Lantis,&nbsp;Paul M. Glat,&nbsp;Marcus Gitterle,&nbsp;Marissa J. Carter,&nbsp;Nathan Young,&nbsp;Charles M. Zelen","doi":"10.1111/iwj.70763","DOIUrl":"https://doi.org/10.1111/iwj.70763","url":null,"abstract":"<p>A novel advanced synthetic bioactive glass matrix was studied in patients with non-healing diabetic foot ulcers (DFUs). Bioactive glasses can be constructed to be biocompatible, with water-soluble materials in multiple geometries including fibre scaffolds that mimic the 3D architecture of a fibrin clot. In this trial, chronic, Wagner Grade 1 DFUs were randomised to receive borate-based bioactive glass Fibre Matrix (BBGFM) plus standard of care (SOC) therapy for 12 weeks or SOC alone. The primary study endpoint was the proportion of subjects that obtained complete wound closure at 12 weeks. Secondary endpoints included time to achieve complete wound closure at 12 weeks. In the modified intent-to-treat (mITT) analysis, 48% (32/67) treated with BBGFM plus SOC healed at 12 weeks compared to 24% (16/66) with SOC alone (<i>p</i> = 0.007). In the per protocol (PP) population, 73% (32/44) of subjects treated with BBGFM plus SOC healed versus 42% (16/38) in the SOC group (<i>p</i> = 0.007). Based on the success of this trial, BBGFM demonstrates faster healing of DFUs compared to SOC and should be considered in the treatment armamentarium for Wagner Grade 1 DFUs. Future trials should investigate the use of BBGFM for healing deeper chronic DFUs, other wound aetiologies, or complex surgical wounds.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70763","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145172055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Baccalaureate Health Students' Experiences of an Online Interprofessional Masterclass to Support Learning About Wound Care: A Multiple Methods Study 本科健康学生在线跨专业大师班支持伤口护理学习的经验:一项多方法研究。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-09-25 DOI: 10.1111/iwj.70765
Karen Ann Theobald, Deirdre O'Donnell, Sandra Johnston, Sharon Neill, Andrea Shepherd, Christina Narelle Parker
{"title":"Baccalaureate Health Students' Experiences of an Online Interprofessional Masterclass to Support Learning About Wound Care: A Multiple Methods Study","authors":"Karen Ann Theobald,&nbsp;Deirdre O'Donnell,&nbsp;Sandra Johnston,&nbsp;Sharon Neill,&nbsp;Andrea Shepherd,&nbsp;Christina Narelle Parker","doi":"10.1111/iwj.70765","DOIUrl":"10.1111/iwj.70765","url":null,"abstract":"<p>Limited evidence exists regarding the effectiveness of learning approaches in supporting interprofessional wound care education transnationally. The aim of this pilot study was to explore the feasibility and preliminary impact of an international, online interprofessional masterclass in supporting baccalaureate health students' learning about wound care. Data were collected using multiple methods including quantitative survey, qualitative focus groups, and interviews with baccalaureate nursing, pharmacy, dietetics, podiatry and paramedicine students from two universities based in Australia and Northern Ireland. A retrospective pre-test design was used. A survey retrospectively assessed students' self-reported confidence and understanding before and after the masterclass, while qualitative methods explored students' experiences of interprofessional learning and wound care. Self-reported improvements in students' understanding of wound assessment and management, as well as heightened awareness of interprofessional contributions to patient care indicated the potential value of this interprofessional and international collaboration in supporting wound care education. Qualitative analysis identified four themes: recognising a wound is a person's wound; comparing international healthcare practices; fostering learner engagement; interprofessional recognition, acknowledgment, and understanding of each profession's roles, contributions and expertise. This pilot study has highlighted key issues to be addressed in future research examining the impact of a collaborative online international initiative on baccalaureate students' interprofessional learning about wound care.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70765","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145137704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of Artificial Intelligence-Driven Wound Care Management to Enhance Access to Care Rural and Northern Communities 使用人工智能驱动的伤口护理管理来提高农村和北方社区的护理可及性。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-09-23 DOI: 10.1111/iwj.70767
Shannon Freeman, Matthew J. Sargent, Laura Rodriguez Galarza, Richard McAloney, Emma Rossnagel
{"title":"Use of Artificial Intelligence-Driven Wound Care Management to Enhance Access to Care Rural and Northern Communities","authors":"Shannon Freeman,&nbsp;Matthew J. Sargent,&nbsp;Laura Rodriguez Galarza,&nbsp;Richard McAloney,&nbsp;Emma Rossnagel","doi":"10.1111/iwj.70767","DOIUrl":"10.1111/iwj.70767","url":null,"abstract":"<p>Wound care remains a high-priority area for improvement in the Canadian health care system. Older adults aged 65 and older are disproportionately affected by chronic and non-healing wounds and often experience multiple co-morbid conditions, challenges which can be further complicated by living in rural and northern areas. A workshop-based multi-methods study was conducted to describe rural and northern perspectives on opportunities and feasibility to implement innovative wound care technologies. Each workshop included pre- and post- workshop surveys, a live demonstration of Swift Skin and Wound, a Q&amp;A session, and facilitated discussion exploring the technology's feasibility, usability, and accessibility in northern and rural care contexts. Participants who volunteered for the study included care staff and healthcare executives (<i>N</i> = 11), described their perspectives on implementing AI-driven digital wound care management solutions with a focus on integration into health care settings. Three themes were identified including: confidence and optimism in improving wound care management, recognition of the superiority of AI-driven digital wound care solutions over current practices, and the importance of adaptable change processes for successful adoption. While generalizability may be limited, findings suggest that adopting AI-driven wound care tools could improve wound assessment accuracy and streamline care for aging populations in rural and northern areas.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 10","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70767","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wound Care Knowledge of Community Pharmacists and Pharmacy Staff: A Cross-Sectional Survey 社区药师和药学人员伤口护理知识的横断面调查。
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-09-18 DOI: 10.1111/iwj.70766
Daisy H. K. Cheung, Carl R. Schneider, Jack C. Collins, Irene S. Um
{"title":"Wound Care Knowledge of Community Pharmacists and Pharmacy Staff: A Cross-Sectional Survey","authors":"Daisy H. K. Cheung,&nbsp;Carl R. Schneider,&nbsp;Jack C. Collins,&nbsp;Irene S. Um","doi":"10.1111/iwj.70766","DOIUrl":"10.1111/iwj.70766","url":null,"abstract":"<p>Chronic wounds pose a public health challenge, with community pharmacists increasingly recognised for their potential role in wound care. Since all chronic wounds originate from acute wounds, pharmacists can play a proactive role in preventing chronicity. Assessing pharmacy staff's wound care knowledge is essential as initiatives to enhance their involvement are underway in Australia. This study aimed to assess wound care knowledge among pharmacists and non-pharmacist staff in Australian community pharmacies. A national cross-sectional electronic survey was conducted between January and August 2022. Developed with multidisciplinary experts, it assessed understanding of wound healing, referral protocols, wound identification, management, and dressing selection. Descriptive and content analyses were performed, and multivariate linear regression identified predictors of knowledge scores. Of 120 responses, 70% were pharmacists, 14% non-pharmacist staff, and 16% unspecified. The median knowledge score was 27 out of 37 (IQR = 21, 30; range = 5–37). Profession, experience, and prior training were significant predictors of higher scores (<i>p</i> &lt; 0.001, <i>R</i><sup>2</sup> = 0.347). Dressing knowledge was weakest, with only 10 out of 103 respondents (9.7%) correctly identifying all types and applications. Critical knowledge gaps underscore the need for targeted educational interventions for pharmacy staff.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 9","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12445117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145080663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Choice of Primary Repair in Animal Bite Wound: A Novel Management Strategy 动物咬伤初级修复的选择:一种新的治疗策略
IF 2.5 3区 医学
International Wound Journal Pub Date : 2025-09-14 DOI: 10.1111/iwj.70761
Yi-Shang Yu, Lin-Yin Wang, Shi-Wei Yang, Chih-Hsin Wang
{"title":"Choice of Primary Repair in Animal Bite Wound: A Novel Management Strategy","authors":"Yi-Shang Yu,&nbsp;Lin-Yin Wang,&nbsp;Shi-Wei Yang,&nbsp;Chih-Hsin Wang","doi":"10.1111/iwj.70761","DOIUrl":"https://doi.org/10.1111/iwj.70761","url":null,"abstract":"<p>Animal bites, primarily from dogs and cats, pose a significant threat, especially to children. Wound infections are common complications caused by bacterial flora in the animal's mouth, making surgical debridement and delayed primary closure the standard treatment. However, recent studies reported no increased infection rates with primary closure compared to delayed closure after adequate debridement, particularly for facial wounds. Primary closure offers better cosmetic and functional outcomes. This study presents a case series to guide decision-making on primary suturing versus leaving wounds exposed. Thirty patients with animal bites underwent surgery, including 23 dog bites and seven cat bites. Eight patients with deep facial lacerations from dog bites received immediate debridement and primary closure with epidermal and subcutaneous sutures. None developed infections, and the cosmetic results were excellent. In contrast, all seven cat bite wounds and nine infected dog bite wounds involved high-risk factors, such as puncture wounds, hand injuries or diabetes. For high-risk wounds, early debridement and leaving the wound open after initial treatment proved effective. Primary repair of facial dog bite injuries, even complex ones, is safe and yields good aesthetic outcomes. For high-risk wounds, leaving them open after debridement is recommended to minimise infection risks.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"22 9","pages":""},"PeriodicalIF":2.5,"publicationDate":"2025-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70761","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145057935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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