International Wound Journal最新文献

{"title":"Candida Drug Resistance in Patients With Diabetic Foot Ulcers: A Systematic Review and Meta-Analysis.","authors":"Mohammad Hossein Ekvan, Hojjat Sayyadi, Sarina Alidadpour, Masoume Karimi, Muhammad Ibrahim Getso, Ahmad Reza Ebrahimi, Mohammad Mirpanahi, Omid Raiesi","doi":"10.1111/iwj.70900","DOIUrl":"https://doi.org/10.1111/iwj.70900","url":null,"abstract":"<p><p>Diabetic foot ulcers (DFUs) are one of the most serious and common complications that, if not treated properly, can lead to potential damage and even amputation. The aim of this systematic review and meta-analysis was to assess the drug-resistant Candida species in DFU. PubMed, Web of Science, Scopus and Google Scholar databases were systematically searched for eligible articles up to 22 June 2024. All articles on Candida diabetic foot infections that reported data on drug resistance were included in the study. In addition to general information, data on the type and number of fungi and the percentage of resistance to each drug were collected for analysis. A total of 238 studies were screened and finally, 16 articles were selected and analysed. Candida albicans was the most frequently isolated species in DFUs, followed by Candida tropicalis and Candida parapsilosis. For antifungal agents, the highest resistance was reported to Nystatin (32.48%, p-value = 0.30), Itraconazole (19.46%, p-value = 0.001) and Fluconazole (16.4%, p-value = 0.001). Miconazole (1.18%, p-value = 0.54) and Caspofungin (4.69%, p-value = 0.01) had the lowest resistance rates. For all drugs, resistance was higher in C. albicans than in non-albicans. This study found that antifungal drug resistance in Candida species is high in patients with DFUs, especially to itraconazole and fluconazole. Caspofungin, micafungin and voriconazole were more effective. Antifungal treatment in these patients should prioritize agents with lower resistance rates to improve outcomes and reduce the risk of treatment failure. Protocol Registration: PROSPERO-CRD42024567133.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 5","pages":"e70900"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111800/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of Acellular Intact Fish Skin Grafts for Treating Acute and Chronic Wounds.","authors":"Christopher Böddeker, Sarah Biermann, Theresa Maria Jansen, Bernhard Homey, Norman-Philipp Hoff","doi":"10.1111/iwj.70931","DOIUrl":"https://doi.org/10.1111/iwj.70931","url":null,"abstract":"<p><p>Acute, chronic, and hard-to-heal wounds pose a growing challenge due to reduced patient quality-of-life, higher cost and increased hospital admissions. Although there is no gold standard for wound care, there is a trend toward simple, outpatient-compatible treatment options. Acellular dermal fish skin derived from Gadus morhua (Atlantic cod) is a promising alternative. This retrospective study evaluated the surgical procedures and outcomes associated with fish-skin graft transplantation for difficult-to-treat wounds. Forty-four patients (33 male and 11 female; mean age: 72.4 years; mean wound area: 84.5 cm²) were treated with acellular fish skin graft. Wound healing was assessed by photographic documentation, confocal microscopy and clinical evaluation. Patient satisfaction was assessed using a structured questionnaire. A positive effect on wound healing, defined as a reduction in wound size, was observed in 88.6% of cases, with complete wound closure in 45.45% of cases. Most patients reported that the procedure was neither painful nor time-intensive; 95% stated that they would opt for treatment again. Fish skin grafting has also shown beneficial outcomes in complex cases, such as in wounds secondary to pyoderma gangrenosum and wounds with exposed bone. Fish skin graft transplantation represents a safe, well-tolerated and effective option for managing chronic wounds as well as challenging postoperative wounds, such as those at anatomically challenging sites.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 5","pages":"e70931"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13120852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lower Limb Symmetry Index in Cavus and Normal Feet by Means of a Baropodometric Platform: A Case-Control Study.","authors":"Lucía Martínez-Salvador, Helena Silva-Migueis, Ricardo Becerro-de-Bengoa-Vallejo, Marta Elena Losa-Iglesias, Javier Bayod-López, Israel Casado-Hernández, Juan Gómez-Salgado, Nuria García-Carrillo, Daniel López-López","doi":"10.1111/iwj.70916","DOIUrl":"10.1111/iwj.70916","url":null,"abstract":"<p><p>High-arched feet affect approximately 10%-15% of the general population. Although the relationship between plantar pressure and bilateral symmetry is well studied, there is limited evidence regarding the use of Symmetry Index and pressure platforms. The objective of the study is to compare dynamic foot pressures and Symmetry Index during gait between subjects with Pes Cavus and subjects with normal feet. The analysis of asymmetric pressure patterns could benefit from studies that compare dynamic foot pressures and Symmetry Index values in subjects with high-arched feet and normal feet. This analysis can promote better clinical understanding of gait alterations and help solve biomechanical problems that may lead to pathologies, as well as prevent and treat them. A descriptive case-control study was developed from October to December 2024 with 82 participants, 41 with Pes Cavus and 41 normal feet and 71 females of 25.52 ± 5.99 years through a consecutive nonrandom technique. For this study, a baropodometry platform (Neo-Plate, Herbitas) was used, which acquired dynamic gait with a 2-step protocol. The inclusion criteria regarding the selection of subjects were age 18-65 years; if both cavus feet, Navicular Drop Test (NDT) < 9 mm; neutral feet and no lower limb problem or surgery. Regarding SI use, the PC demonstrated to have large asymmetries compared to the control group. Left anterior pressure was lower (44.93% ± 4.59% vs. 48.60% ± 3.43%, p = 0.014), left posterior pressure was higher (55.07% ± 4.58% vs. 51.40% ± 3.43%, p = 0.013) and the left Initial Contact Phase (ICP) was prolonged (123.34 ± 51.75 ms vs. 91.30 ± 31.86 ms, p = 0.036); right medial pressure was higher (58.18% ± 4.08% vs. 53.77% ± 4.79%, p = 0.034). SI measurements were greater in normal foot group than in the PC group with SI 94.15% ± 5.00% versus 93.75% ± 4.59%, p = 0.001, respectively; ICP and lateral SI were both p = 0.001. Findings confirmed that subjects with cavus feet tend to present greater alterations in bilateral symmetry, specifically posteromedial pressure movements and altered gait phases, which are indicative of more probability of future injuries. For this reason, pressure platforms are excellent tools for understanding, analysing and therefore applying the correct treatment according to the SI.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 5","pages":"e70916"},"PeriodicalIF":2.5,"publicationDate":"2026-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13128319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of AOPT Combined With Collagen Dressings on Facial Flushing and Skin Barrier Function in Patients With Rosacea","authors":"Jinzhu Mao,&nbsp;Mengyao Yang","doi":"10.1111/iwj.70902","DOIUrl":"10.1111/iwj.70902","url":null,"abstract":"<p>This study aimed to evaluate the efficacy of advanced optimal pulse technology (AOPT) combined with collagen dressings on facial flushing and skin barrier function in patients with rosacea. A total of 150 patients with rosacea were prospectively enrolled and randomised into the control group (<i>n</i> = 75, received AOPT treatment alone) and observation group (<i>n</i> = 75, additionally used recombinant human type III collagen dressing). Clinical improvement, erythema and lesion features were recorded before and 12 weeks after therapy. Patient quality of life was measured using the Acne-QOL scale. Skin barrier function was evaluated by transepidermal water loss (TEWL), sebum output and epidermal hydration. Serum inflammatory markers were analysed, and adverse reactions and recurrence were also tracked. Following 12 weeks of treatment, compared to the control group, the observation group showed higher overall effectiveness, greater reduction in erythema, lesion severity and pain scores, higher Acne-QOL scores across all dimensions (self-perception, emotional well-being, symptom burden and social function), lower TEWL and sebum secretion, higher hydration and lower levels of TNF-α, hs-CRP and PCT (all <i>p</i> &lt; 0.05). There was no significant difference in the incidence of adverse reactions between the two groups (2.67% vs. 6.67%, <i>p</i> = 0.246), but the observation group had a lower recurrence rate (2.67% vs. 14.67%, <i>p</i> = 0.009). The combination of AOPT with collagen dressing offers superior benefits over AOPT alone, alleviating facial flushing, strengthening the skin barrier, decreasing systemic inflammation and reducing relapse, highlighting its clinical value in rosacea management.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70902","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147672952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Continuous Pressure Monitoring to Inform Decisions for Pressure Injuries in the Community: Secondary Analysis Using a Mobility and Pressure Exposure Algorithm","authors":"Nicci Aylward-Wotton,&nbsp;Silvia Caggiari,&nbsp;Bridie Kent,&nbsp;Liudi Jiang,&nbsp;Rashedul Hoque,&nbsp;Peter R. Worsley","doi":"10.1111/iwj.70896","DOIUrl":"https://doi.org/10.1111/iwj.70896","url":null,"abstract":"<p>Frailty in community-dwelling individuals often leads to prolonged periods in bed or sitting, increasing their risk of pressure injury development. The Quality Improvement project ‘Pressure Reduction through cOntinuous Monitoring In the community SEtting’ (PROMISE) implemented the use of continuous pressure monitoring (CPM) to inform interventions. A secondary analysis of PROMISE data involving 17 patients was examined before and after the intervention. A novel algorithm using duration and magnitude of pressure signatures at the buttock area was estimated from the CPM data and an algorithm based on the sigmoid relationship between pressure and time was used to categorise risk pre- to post-intervention. The CPM intervention helped inform changes in support surface, posture and mobility advice. Duration and magnitude of pressure signatures revealed a high degree of inter-subject variability. At baseline 35% of (6/17) patients spent prolonged periods with potentially harmful interface pressures (high to very high exposure). Trends of improvements post-PROMISE intervention were observed, with 24% (4/17) in these higher exposure categories. This study demonstrated how CPM could be used to inform interventions for individuals living with pressure injuries in the community. An algorithm was used to understand trends in posture, mobility, and pressure exposure, showing some improvement pre- to post-intervention.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/iwj.70896","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147668573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translation, Validation and Cross-Cultural Adaptation of the Patient and Observer Scar Assessment Scale Version 3.0 (POSAS 3.0) Into Malay Language for Injury-Related Scar","authors":"Ken Wong Siong Hou,&nbsp;Gan Chun Hong,&nbsp;Mohd Johar Jaafar,&nbsp;Roszalina Ramli","doi":"10.1111/iwj.70917","DOIUrl":"10.1111/iwj.70917","url":null,"abstract":"<p>Patient and Observer Scar Assessment Scale Version 3.0 (POSAS 3.0) is a robust instrument for scar evaluation. Currently, no validated POSAS 3.0 in the Malay language is available. This study aimed to translate, culturally adapt, and psychometrically evaluate POSAS 3.0 for Malay-speaking populations in Malaysia. Malaysian patients were recruited between 31 October 2023, to 31 December 2024. Translation was conducted using a forward and backward translation approach. Reliability was assessed using internal consistency (Cronbach's alpha) and test–retest. Face validity was addressed with 10 patients, and content validity was evaluated by four clinical specialists. Content validity was evaluated using the item-content validity index (I-CVI) and content validity ratio (CVR). Construct validity was assessed using exploratory factor analysis (EFA). Seventy-eight participants with facial (<i>n</i> = 39, 50.0%) and non-facial (<i>n</i> = 39, 50.0%) soft tissue scars were recruited for the EFA. The Malay POSAS-O demonstrated acceptable internal consistency (<i>α</i> = 0.75) and excellent inter-rater reliability, with item-level intraclass correlation coefficient (ICCs) ranging from 0.91 to 1.00 and total score ICC of 0.99. Agreement for categorical scar severity ratings was almost perfect (κ = 0.89). The Malay POSAS-P showed excellent internal consistency (<i>α</i> = 0.89), and test–retest reliability for the total score was good to excellent (ICC = 0.89). Intermittent symptom items (painful, shooting, burning and fragile) exhibited lower stability, reflecting natural symptom variability. Content validity was excellent, with all items achieving I-CVI and CVR values of 1.00. EFA supported construct validity, with adequate Kaiser-Meyer-Olkin (KMO) values (POSAS-O: 0.88; POSAS-P: 0.85), significant Bartlett's tests, strong communalities and factor loadings. The cumulative variance explained was 79.05% for POSAS-O and 68.19% for POSAS-P. The Malay version of the POSAS 3.0 is a reliable, valid, and culturally appropriate instrument for scar assessment. Its strong psychometric properties support its application in clinical practice and research involving Malay-speaking populations.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13065433/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147645098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Evaluation of a Novel Synthetic Nanofiber Wound Matrix for the Treatment of Chronic Wounds","authors":"Lifang Qian,&nbsp;Jingyun Fang,&nbsp;Yong He,&nbsp;Meiqin Ni,&nbsp;Yiyu Sun,&nbsp;Sean Chen","doi":"10.1111/iwj.70908","DOIUrl":"10.1111/iwj.70908","url":null,"abstract":"<p>Chronic wounds, including Diabetic Foot Ulcers (DFUs), Venous Leg Ulcers (VLUs) and Pressure Ulcers (PUs), present significant challenges for the patients, clinicians and healthcare systems. There remains a strong need for novel and effective technologies to accelerate the healing of these wounds. The objective of this prospective, single-arm pilot study was to evaluate the clinical performance of a novel nanofiber wound matrix for the treatment of chronic lower extremity wounds refractory to standard-of-care treatment at a single centre. A total of 15 patients with 15 chronic wounds (5 DFUs, 8 VLUs and 2 PUs) were included in this study. These wounds were non-healing to previous standard-of-care treatments for an average of 4 weeks. They were all treated with the novel nanofiber wound matrix with weekly clinical evaluation and re-application for a total duration of four (4) weeks, per the study protocol. The average wound area reduction (WAR) was 83.6% upon 4 weeks of treatment with the application of the subject wound matrix, as an adjunctive measure to the standard of care. Additionally, seven (7) of the 15 wounds (46.7%) completely healed starting from Week 3, and the average complete healing time was 13.9 days. These results demonstrated accelerated healing effects of the subject wound matrix, when compared to the standard of care reported in literature, where the average WAR was at 62.9% at Week 12, six (6) of the 18 wounds (33.3%) were completely healed within 12 weeks, and the average complete healing time was 49.0 days. These results demonstrated that the subject wound matrix is a safe and effective novel technology in treating chronic wounds, providing significant clinical and economic benefits for patients with various chronic wounds.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13062494/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147638863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Mass Index: A Key Factor in Surgical Site Infections After Kidney Transplantation?","authors":"Mohamed El-Mahrouk,&nbsp;Raphaela Sorgnitt,&nbsp;Gerold Schwantzer,&nbsp;Robert Karitinig,&nbsp;Derar Jaradat,&nbsp;Zoltan Mathe,&nbsp;Robert Sucher,&nbsp;Daniela Kniepeiss","doi":"10.1111/iwj.70901","DOIUrl":"10.1111/iwj.70901","url":null,"abstract":"<p>Kidney transplant recipients are at increased risk of surgical site infections (SSIs) due to procedural complexity and immunosuppression. This retrospective single-centre study examines the influence of BMI on SSI risk and identifies common pathogens. A total of 230 renal transplant patients were included in this analysis 2017 and 2019. All patients received a cephalosporin for prophylaxis, and wound swabs were taken from those who developed SSIs. SSIs occurred in 45 patients (19.6%) and were not significantly associated with age, sex or donor type. The most common organisms were coagulase-negative staphylococci (26.7%), <i>Staphylococcus epidermidis</i> (24.4%), <i>Enterococcus faecalis</i> (22.2%) and <i>Candida albicans</i> (22.2%). SSIs were significantly linked to surgical revision (<i>p</i> &lt; 0.001) and higher BMI (<i>p</i> = 0.027). A BMI ≥ 28.1 was associated with threefold higher odds of SSIs (OR = 3.0; <i>p</i> = 0.001). Each one-unit increase in BMI was associated with a 7.2% increase in the odds of SSI occurrence (OR = 1.072; <i>p</i> = 0.020). Staphylococcus (<i>p</i> = 0.019) and Enterococcus (<i>p</i> = 0.048) infections were more common in patients with BMI &gt; 28.1. Therefore, SSIs are a frequent complication posttransplant and are strongly associated with high BMI. Standard antibiotic regimens may not cover all relevant pathogens in obese patients, underscoring the need for tailored prophylactic strategies.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13056484/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147632214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Alginate and Chitosan-Based Hydrogels for the Treatment of Radiation Dermatitis","authors":"Zintle Mbese,&nbsp;Omobola Oluranti Okoh,&nbsp;Blessing Atim Aderibigbe","doi":"10.1111/iwj.70884","DOIUrl":"10.1111/iwj.70884","url":null,"abstract":"<p>Radiation dermatitis (RD) remains a prevalent and challenging adverse effect of radiotherapy in cancer patients, significantly impairing patient quality of life and potentially interrupting treatment regimens. In recent years, the development of biopolymer-based hydrogels has emerged as a promising strategy for preventing and managing RD. Among these, alginate and chitosan-based hydrogels have attracted considerable attention due to their excellent biocompatibility, biodegradability, and wound-healing properties. This comprehensive review highlights the therapeutic efficacy of alginate/chitosan composite hydrogels in RD management. The unique physicochemical characteristics of these hydrogels, including moisture retention, oxygen permeability, and controlled drug release capabilities, make them ideal candidates for treating radiation-induced skin injuries. Mechanistically, these hydrogels exert anti-inflammatory, antioxidant, and antimicrobial effects while promoting re-epithelialization and collagen, which are critical in skin repair. Preclinical studies revealed significantly reduced RD severity scores and histopathological improvements following hydrogel application. Although clinical translation remains limited, initial trials showed promising outcomes in human subjects. Overall, alginate/chitosan hydrogels represent an effective system with immense potential to revolutionize RD management in oncological care.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053172/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge, Attitudes, and Practices of Nurses Regarding Pressure Injury Prevention and Management in Nablus, Palestine: A Cross-Sectional Study","authors":"Loai M. Zabin,&nbsp;Baraa F. Shayeb,&nbsp;Shorouq H. Draedi,&nbsp;Sa'ed. H. Zyoud,&nbsp;Abdullah Abdullah,&nbsp;Mohammad Faisal Al Ali,&nbsp;Mohammed F. Hayek","doi":"10.1111/iwj.70897","DOIUrl":"10.1111/iwj.70897","url":null,"abstract":"<p>Pressure injuries are largely preventable yet remain common in hospital care. This multi-hospital study assessed nurses' knowledge, attitudes and practices for prevention in governmental, private and charitable hospitals in Nablus, Palestine, and examined links with professional characteristics. A descriptive cross-sectional study was conducted in six hospitals in Nablus city, Palestine. A total of 231 registered nurses were recruited using convenience sampling and completed a content-validated, self-administered questionnaire assessing demographics, knowledge (20 items), attitudes (11 items), and practices (17 items). Data were analysed using descriptive statistics, one-way analysis of variance with Tukey post hoc tests, and binary logistic regression for adequate knowledge and practice (≥ 80%). Overall, 64.5% demonstrated adequate knowledge, and 58.0% expressed a favourable attitude. Practice adherence averaged 70.9 ± 16.3 out of 100. Only 31.6% achieved ≥ 80%, indicating suboptimal practice in most participants. Key gaps involved massage avoidance and the use of lifting devices. Knowledge was higher with recent PI training (1–2 years vs never: OR = 4.110, 95% CI 1.622–10.414, <i>p</i> = 0.003; 2–3 years vs never: OR = 3.047, 95% CI 1.208–7.687, <i>p</i> = 0.018). Practice adequacy was higher with training &lt; 1 year ago vs never (OR = 4.146, 95% CI 1.636–10.512, p = 0.003). Other adjusted associations were imprecise and treated as exploratory. Nurses showed generally adequate knowledge, whereas routine preventive practice remained less consistent. Recent training was associated with better knowledge and practice, suggesting that targeted education, supervised skills training, unit-level protocols and audit with feedback may support improvement.</p>","PeriodicalId":14451,"journal":{"name":"International Wound Journal","volume":"23 4","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-04-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13053655/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147627749","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}