International Journal of STD & AIDS最新文献

{"title":"Barriers to HIV pre-exposure prophylaxis uptake for men who have sex with both men and women: A global scoping review.","authors":"Jodie Crossman, Daniel Richardson","doi":"10.1177/09564624251321564","DOIUrl":"10.1177/09564624251321564","url":null,"abstract":"<p><p>BackgroundAlthough PrEP is a highly effective HIV prevention method, some groups are underrepresented in PrEP uptake. Much HIV prevention research groups gay, bisexual and other men who have sex with men together; however, men who have sex with both men and women (MSWM) may have needs distinct from those who identify as exclusively gay. This scoping review aims to explore documented barriers to PrEP use among MSWM.MethodsLiterature was searched using four databases. Studies were included if data referring to MSWM were reported as a distinct category. Data were extracted using a standardised form, and findings were stratified into relevant categories of the social ecological framework.ResultsAlongside intersectional barriers, MSWM were found to have lower awareness of PrEP, and access sexual health services less than men who have sex only with men. Those who did not identify with the LGBT community often missed out on health promotion messages for this group and were less likely to be offered HIV prevention interventions. MSWM identified more stigmatisation around PrEP use than gay men. However, when aware of PrEP, MSWM were very motivated to use this intervention.ConclusionsNot all MSM will identify within the LGBTQ + community and may miss out on valuable opportunities for HIV prevention. PrEP information should be widely available in a variety of health and community settings. Health care professionals should avoid assumptions when assessing patients and provide information about HIV and STI prevention to all attending sexual health services.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"450-468"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143449023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Granulomatous vulvitis complicated by polymicrobial growth.","authors":"Divya Madonna Dsouza, Jacintha Martis, Rochelle Cheryl Monteiro, Jyothi Jayaraman, Prajna Shetty","doi":"10.1177/09564624251318086","DOIUrl":"10.1177/09564624251318086","url":null,"abstract":"<p><p>Granulomatous vulvitis (GV) is a rare chronic inflammatory condition presenting with persistent vulvar swelling and noncaseating granulomas, often mimicking Crohn's disease and sarcoidosis. We report a 21-year-old sexually inactive woman with a five-month history of painless vulvar swelling and occasional itching, complicated by secondary polymicrobial infection. A thorough evaluation excluded other granulomatous diseases, and histopathology revealed noncaseating granulomas, supporting the diagnosis of granulomatous vulvitis. Initial antibiotic therapy was followed by hydroxychloroquine, and intralesional triamcinolone, leading to marked symptom resolution. This case highlights intralesional corticosteroids as an effective first-line treatment and underscores the need for a multidisciplinary and personalized approach in managing GV, particularly in the presence of secondary infections.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"510-512"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143189183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2025 European guideline on the management of <i>Chlamydia trachomatis</i> infections.","authors":"John A White, Nicole Htm Dukers-Muijrers, Christian Jpa Hoebe, Chris R Kenyon, Jonathan Dc Ross, Magnus Unemo","doi":"10.1177/09564624251323678","DOIUrl":"10.1177/09564624251323678","url":null,"abstract":"<p><p>Sexually transmitted <i>Chlamydia trachomatis</i> infections remain common globally and most frequently are asymptomatic. The 2025 European <i>C. trachomatis</i> guideline provides up-to-date guidance regarding indications for testing and treatment of <i>C. trachomatis</i> infections. It includes advice on urogenital and extragenital <i>C. trachomatis</i> testing including the use of self-collected specimens; recommendation to use only validated NAATs for diagnosis; and recommendation to treat all <i>C. trachomatis</i> infections with doxycycline as first line in preference to single-dose azithromycin regimens. The absence of evidence and limited value of broad screening in asymptomatic populations for <i>C. trachomatis</i> infections is also discussed.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"434-449"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143556944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing diagnostic accuracy of congenital syphilis using penicillin administration data through the Pediatric Health Information System (PHIS) database.","authors":"John M Flores, Natalie Grills, Jason M Kane, Lilly Cheng Immergluck, Nikki Kasal, Madan Kumar, Allison Bartlett","doi":"10.1177/09564624251324981","DOIUrl":"10.1177/09564624251324981","url":null,"abstract":"<p><p>BackgroundGiven the most recent report of the nationwide rise of congenital syphilis (CS), with over a 773% increase from 2012 to 2021 per the Center for Disease Control and Prevention, we sought to utilize penicillin administration and ICD-10 billing data as proxies to assess the accuracy of diagnosis of congenital syphilis among major tertiary care pediatric hospitals.MethodsThis retrospective cohort study drawing data from 49 major tertiary children's hospitals in the United States sought to determine whether administration of penicillin in infants 30 days or younger, excluding other common infectious diseases treated with the medication, correlated with recently reported congenital syphilis epidemiologic data.Results2290 infants met inclusion criteria and received penicillin therapy, excluding infants with the most common secondary infections treated with penicillin, with 1123 (49.3%) of those included not having a syphilis diagnosis made. Of the neonates with a coded diagnosis of CS, (1107/1162) 95.3% received more than 1 day of penicillin therapy, and those not coded for CS that received more than 1 day of penicillin therapy was 37.9% (428/1128).ConclusionsOur findings found a significant number of infants who had penicillin administration and laboratory and procedural workup performed suggestive of congenital syphilis consideration, without a congenital syphilis diagnosis billed. This may reflect an underestimation of what is notably a growing nationwide pandemic. By addressing the screening and treatment needs of patients with CS, we can help to address some of the socioeconomic inequities in pediatric and maternal healthcare, and further accurately characterize the extent of this increasingly prevalent disease process.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"475-486"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143530987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correlates of HIV testing among men in Ghana: Cross-sectional analysis of the 2022 demographic and health survey.","authors":"Sulemana Ansumah Saaka, Roger Antabe, Isaac Luginaah","doi":"10.1177/09564624251324976","DOIUrl":"10.1177/09564624251324976","url":null,"abstract":"<p><p>IntroductionNew HIV infections are on the rise in Ghana, with approximately 16,574 new cases reported in 2022 alone. Although HIV prevalence rate is higher among women aged 15-49 years (2.0 [1.7-2.3]) than men aged 15-49 (1.0 [0.8-1.2]) in Ghana, evidence form the country's 2022 Demographic and health Survey suggest that only 12% of men had ever been tested for HIV once in their lifetime relative to 17% of women, and yet more men (35%) than women (23%) reported having sexual intercourse with persons who were neither their wife nor live-in partners. More so, the Ghana National HIV and AIDS Policy has over the years positively influenced the utilization of HIV testing (HIVT) services among women in Ghana through antenatal care visits. While this policy encourages women to undertake testing with their husbands, most men in the Ghanaian Context rarely accompany their spouse to antenatal care due to several reasons including conflicting work schedules, thus limiting their chances of getting tested. Using a nationally representative dataset, this study adds to the broader literature by exploring the factors associated with HIVT among men.MethodsUsing the 2022 Ghana Demographic and Health Survey (<i>N</i> = 7044 males), and employing multiple logistic regression models, this study explored the factors associated with HIVT among men.ResultsMarried men (OR = 1.723; <i>p</i> < .001), the employed, particularly, those paid in cash only (OR = 2.021; <i>p</i> < .001) and those paid both in cash and kind (OR = 1.823; <i>p</i> < .001), those who had knowledge of HIV test kits (OR = 1.708; <i>p</i> < .001), aware and approve to use Pre-Exposure Prophylaxis (PrEP) (OR = 1.1280; <i>p</i> < .001), as well as those who visited a health facility in the past 6 months (OR = 1.615; <i>p</i> < .001), all significantly reported higher odds of testing. Moreover, Educational attainment, age, household wealth, religion, ethnicity, and the region of residence significantly predicted HIVT in the study context.ConclusionSocio-demographic, economic, geographic and health-related factors have significant influence on the uptake of HIVT among men in Ghana, thus underscoring the need for tailored interventions that consider diverse contextual factors in HIV prevention and healthcare delivery.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"487-497"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12014958/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tofacitinib in alopecia areata and HIV: A curious intersection of immunomodulation, hair regrowth, and hypertrichosis.","authors":"Tanvi Vaidya, Monisha Madhumita","doi":"10.1177/09564624251315781","DOIUrl":"10.1177/09564624251315781","url":null,"abstract":"<p><p>Tofacitinib is a Janus kinase 3 (JAK3) inhibitor effective in treating alopecia areata (AA) by promoting hair regrowth. Its mechanism may involve upregulation of vascular endothelial growth factor (VEGF) and reduction of inflammation. However, the range of effects, particularly on hair growth in specific populations, remains under-investigated. We describe a patient with HIV, well-controlled on antiretroviral therapy, who developed hirsutism after starting tofacitinib for AA. This unexpected side effect of hypertrichosis was completely resolved after discontinuing the medication and undergoing a single session of laser hair removal (LHR). This case highlights the potential for unusual hair growth patterns associated with tofacitinib treatment in patients with immune dysregulation. Monitoring and management strategies for such side effects are discussed. This case highlights the potential for unusual hair growth patterns associated with tofacitinib treatment in patients with immune dysregulation. Monitoring and management strategies for such side effects are discussed. The case emphasizes the need for careful monitoring of hair growth and other potential side effects in patients on tofacitinib, especially those with underlying immune-modulating conditions. It also suggests that LHR can be an effective treatment for medication-induced hirsutism.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"423-426"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143122980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"2024 British Association for Sexual Health and HIV (BASHH) UK national guideline on the management of vulval conditions.","authors":"Sarah K Edwards, Fiona Lewis, Imali Fernando, Lisa Haddon, Deepa Grover","doi":"10.1177/09564624241311629","DOIUrl":"10.1177/09564624241311629","url":null,"abstract":"<p><p>BackgroundThe management of vulval disorders in Genitourinary Medicine (GUM) clinics requires targeted approaches due to the wide range of conditions affecting the vulva. Vulval diseases encompass various aetiologies, including dermatoses, pain syndromes, and pre-malignant conditions, necessitating specialized care often involving multidisciplinary collaboration.PurposeThis guideline aims to provide evidence-based recommendations for the diagnosis and management of specific vulval conditions that may present in GUM clinics. The focus is on conditions commonly managed by Genitourinary Physicians, either independently or in partnership with other specialists, depending on available local expertise. Additionally, guidance on onward referral is included to ensure optimal patient care.Study SampleThe guideline primarily addresses the management of individuals aged 16 years and older presenting to GUM clinics with non-infective vulval conditions.Data CollectionRecommendations within this guideline are derived from a review of existing literature, clinical expertise, and consensus among specialists. Emphasis is placed on diagnostic tests and treatment regimens tailored to the following conditions: Lichen sclerosus, Lichen planus, Eczema, Lichen simplex, Psoriasis, Vulval high-grade squamous intraepithelial lesions (previously vulval intraepithelial neoplasia), Vulval pain syndromes, and Non-sexually acquired acute genital ulceration (Ulcer of Lipschütz).ConclusionsThis guideline offers practical recommendations for the effective management of specific vulval disorders in GUM settings. It is not intended to be a comprehensive review of all vulval diseases but rather a focused resource to assist clinicians in providing high-quality, patient-centred care. Onward referral pathways are also outlined to support collaborative and multidisciplinary management of complex cases.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"346-371"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005250","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A correspondence on elevated IL-10 serum levels are associated with slower serological response following syphilis treatment during pregnancy.","authors":"Chenwei Diao, Huan Wang","doi":"10.1177/09564624251315785","DOIUrl":"10.1177/09564624251315785","url":null,"abstract":"","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"427-428"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Determination of depression prevalence in pregnant women living with HIV aged 18 years and older: A meta-analysis study.","authors":"Sibel Gürbüz, Elif Nur Yildirim Öztürk, Simge Sari, Saliha Kazci, Meltem Çöl","doi":"10.1177/09564624251316048","DOIUrl":"10.1177/09564624251316048","url":null,"abstract":"<p><p>BackgroundPregnant women living with HIV are known to be at higher risk of depression than pregnant women without HIV. Accompanied by a systematic literature review, the aim of this study was to determine the global prevalence of depression in pregnant women living with HIV.MethodsPubMed, Scopus, Google Scholar and Web of Science databases were searched. The references of the included publications and a similar meta-analysis study were also reviewed. The 19 included studies were assessed for quality using standard forms. Pooled prevalence was calculated using a random effects model. Heterogeneity and publication bias were assessed using various methods. Subgroup analyses and meta-regression were also performed.ResultsOf the 19 studies included in the review, six of the studies were published between 2008 and 2014, and 13 were published between 2017 and 2023. 15 studies were conducted in African countries. According to study type, eight studies were cross-sectional and seven were cohort studies. The pooled prevalence of depression was calculated to be 45%. The prevalence in African countries was 37.7%. The studies were found to be statistically significantly heterogeneous. Tests and funnel plots showed no publication bias in this meta-analysis. The variables place, study type and scale made the model significant in the meta-regression.ConclusionIn this meta-analysis, 6379 women aged 18 years and older were examined and their depression levels were found to be high. Taking steps to struggle with HIV and depression in people living with HIV seems important.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"406-415"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143052476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of patient portals to disclose STI test histories to sex partners among U.S. men who have sex with men: A call for research and guidance.","authors":"Kevon-Mark P Jackman, Kaitlyn Atkins, Sarah M Murray, Tom Carpino, Iaah Lucas, Travis Sanchez, Stefan Baral","doi":"10.1177/09564624251315783","DOIUrl":"10.1177/09564624251315783","url":null,"abstract":"<p><p>BackgroundThis study investigates the use of patient portals for disclosing sexually transmitted infection (STI) test result histories to sexual partners among men who have sex with men (MSM) in the United States.MethodsUsing data from the 2022-2023 American Men's Internet Survey, this cross-sectional analysis examined demographic, behavioral, and healthcare-related factors associated with MSM's utilization of patient portals for sharing STI test results. Participants (<i>N</i> = 2601) were surveyed on portal use, STI testing frequency, and partner disclosure practices.Results18% of survey participants used portals to disclose a STI test result to parrtners, with higher prevalences among individuals aged 16-37 years old versus 56 years and older, black non-Hispanic (26.4%) versus white non-Hispanic (16.8%), and those reporting nine or more times being tested for STIs (30.1%) versus 1 to 3 times (7.5%). Participants reporting sex work (33.3% vs 17.7%) and HIV pre-exposure prophylaxis (PrEP) use (24.2% vs 13.0%) also had a higher prevalence of portal use for disclosure. Multivariable Poisson regression analysis with robust error variance showed that sexual behavioral stigma from family and friends [adjusted prevalence ratio (aPR) = 1.11; <i>p</i> = .04] also, being tested for STIs four to 8 (aPR = 2.21; <i>p</i> < .001) and nine or more times aPR = 3.42; <i>p</i> < .001) were significantly associated with prevalence of portal-based disclosure.ConclusionFindings suggest patient portals may be viable tools for STI prevention in MSM communities, especially among individuals with increased vulnerability to STI acquisition. Addressing disparities in portal access and explaining patient portal capabilities may enhance the role of digital health in reducing STI transmission among MSM communities.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"388-396"},"PeriodicalIF":1.4,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}