International Journal of STD & AIDS最新文献

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Case-control study on challenges in loss of follow-up care and the limitations in the reach of HIV policies for women. 关于失去后续护理的挑战和妇女艾滋病毒政策覆盖范围局限性的病例对照研究。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-07-21 DOI: 10.1177/09564624241263614
Gabriela Tizianel Aguilar, Guilherme Lamperti Thomazi, Lisiane Acosta, Andrei Fernandes da Rocha, Maria Leticia Rodrigues Ikeda
{"title":"Case-control study on challenges in loss of follow-up care and the limitations in the reach of HIV policies for women.","authors":"Gabriela Tizianel Aguilar, Guilherme Lamperti Thomazi, Lisiane Acosta, Andrei Fernandes da Rocha, Maria Leticia Rodrigues Ikeda","doi":"10.1177/09564624241263614","DOIUrl":"10.1177/09564624241263614","url":null,"abstract":"<p><strong>Introduction: </strong>HIV has transitioned from a devastating 1980s epidemic to a manageable chronic condition with antiretroviral therapy. In Brazil, challenges persist, including high detection rates and loss of medical follow-up among people living with HIV/AIDS (PLHIV). Adherence, engagement, and avoiding loss to follow-up are critical for effective HIV/AIDS prevention and care.</p><p><strong>Objectives: </strong>This case-control study within longitudinal research on PLHIV linkage and retention in Porto Alegre aims to analyze factors associated with treatment abandonment.</p><p><strong>Methods: </strong>The study, based on patients from the Therapeutic Care Service for HIV and AIDS at Sanatorio Partenon Hospital, involved 360 PLHIV in a retention and linkage outpatient clinic.</p><p><strong>Results: </strong>Risk factors for loss to follow-up include cisgender women, diagnosis between 1991 and 2005, and non-adherence to antiretroviral treatment (ART). Conversely, cisgender men, diagnosis between 2015 and 2023, and good ART adherence were protective factors.</p><p><strong>Conclusion: </strong>Gender disparities and ART non-adherence pose significant challenges in comprehensive PLHIV care. Cisgender women diagnosed before 2005 face higher risk, while cisgender men diagnosed after 2015 with good ART adherence are more protected, influencing care and prevention strategies for PLHIV.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Impact of rapid-antiretroviral therapy in a cohort of treatment-naïve migrants living with HIV in a high income setting. 快速抗逆转录病毒疗法对高收入环境中一批治疗无效的艾滋病病毒感染者的影响。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-08-06 DOI: 10.1177/09564624241270970
Sasha Trevisan, Giuseppe Gasparro, Seble Tekle Kiros, Marco Pozzi, Costanza Malcontenti, Irene Campolmi, Riccardo Paggi, Annalisa Cavallo, Alberto Farese, Filippo Ducci, Massimo Meli, Mario Pittorru, Alessandro Bartoloni, Gaetana Sterrantino, Filippo Lagi
{"title":"Impact of rapid-antiretroviral therapy in a cohort of treatment-naïve migrants living with HIV in a high income setting.","authors":"Sasha Trevisan, Giuseppe Gasparro, Seble Tekle Kiros, Marco Pozzi, Costanza Malcontenti, Irene Campolmi, Riccardo Paggi, Annalisa Cavallo, Alberto Farese, Filippo Ducci, Massimo Meli, Mario Pittorru, Alessandro Bartoloni, Gaetana Sterrantino, Filippo Lagi","doi":"10.1177/09564624241270970","DOIUrl":"10.1177/09564624241270970","url":null,"abstract":"<p><strong>Background: </strong>We evaluated the effect of rapid ART (RA) compared to delayed ART (DA) on viral load suppression (viral load <50 cp/mL) and loss to follow-up (LTFU) in a cohort of migrants living with HIV (MLWHs) in Italy.</p><p><strong>Methods: </strong>Data were retrospectively gathered from MLWHs who began care at the Infectious and Tropical Diseases Unit of the Careggi University Hospital from January 2014 to December 2022. RA was defined as antiretrovirals prescribed within 7 days of HIV diagnosis. The study ended on April 30, 2023, or upon patient LTFU. Chi-square and non-parametric tests assessed differences in categorical and continuous variables, respectively. Kaplan-Meyer survival analysis was performed to estimate the probability of loss to follow-up. Cox regression analysis was performed to evaluate factors associated with a loss to follow-up.</p><p><strong>Results: </strong>87 MLWHs were enrolled: 20 (23%) on RA and 67 (77%) on DA. In the RA group there were more PLWH with a previous AIDS event (<i>p</i> < .001) however, there was no significant difference in the LTFU rates between the groups (aHR 0.6, 95%CI 0.1-3.1; <i>p</i> = .560; Logrank = 0.2823). Being an out-of-status MLWH was the only predictor of LTFU. By 6 months, virological suppression was achieved in 61.2% (n = 41) in DA and 70.0% in the RA group (n = 14) (Logrank <i>p</i> = .6747).</p><p><strong>Conclusions: </strong>RA did not significantly affect LTFU rates or the achievement of viral load suppression. The study suggests that further research is needed to assess the impact of RA in high income settings.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Trends in HIV incidence and mortality across Bharat (India) after the emergence of COVID-19. COVID-19 出现后印度巴拉特地区的艾滋病毒发病率和死亡率趋势。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-08-06 DOI: 10.1177/09564624241271945
Karan Varshney, Ashmit D Mustafa
{"title":"Trends in HIV incidence and mortality across Bharat (India) after the emergence of COVID-19.","authors":"Karan Varshney, Ashmit D Mustafa","doi":"10.1177/09564624241271945","DOIUrl":"10.1177/09564624241271945","url":null,"abstract":"<p><strong>Background: </strong>Human immunodeficiency virus (HIV) is a sexually transmitted infection impacting populations worldwide. While there have been major improvements in controlling HIV over recent years, the COVID-19 pandemic may have potentially resulted in major interruptions to this control of HIV. Bharat (India) is a country that has been greatly impacted by the COVID-19 pandemic, and we aimed to analyse the trends in HIV control since the start of the pandemic.</p><p><strong>Methods: </strong>In this study we evaluated changes in rates of HIV incidence and mortality across Bharat for the years both before, and after, the start of the COVID-19 pandemic. Percent and absolute changes were determined, and thereafter, both bivariate and multi linear regression was conducted to evaluate the relationship between COVID-19 burden and changes in HIV epidemiology across the nation.</p><p><strong>Results: </strong>It was shown that, despite the COVID-19 pandemic, annual incidence and deaths of HIV/AIDS have both decreased across Bharat. From 2019-2021, in Bharat, the total number of new HIV cases annually decreased by 9.03%, and the total number of HIV/AIDS deaths annually decreased by 28.82%. A similar trend was shown across most states/union territories; however, there were notable exceptions (such as Karnataka, Bihar, and Assam) where the rates have instead increased.</p><p><strong>Conclusions: </strong>Our analysis has demonstrated that government efforts to control the HIV/AIDS epidemic have not been greatly impacted across the majority of Bharat since the emergence of COVID-19. The reduction in annual HIV/AIDS deaths in the country has been better than the world average, and the improvements from the period of 2019 to 2021 were greater than those from 2017 to 2019. Regardless, there are regions in the nation where the epidemic has instead worsened during this period.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141893343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
HIV and intersectional stigma among people living with HIV and healthcare workers and antiretroviral therapy adherence in the Dominican Republic. 多米尼加共和国艾滋病毒感染者和医护人员对艾滋病毒和交叉性污名以及坚持抗逆转录病毒疗法的情况。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-07-22 DOI: 10.1177/09564624241259801
Jelani Kerr, Ibrahim Yigit, Dustin M Long, Robert Paulino-Ramírez, John Waters, Jiaying Hao, Laura Nyblade, Nelson Varas-Díaz, Sylvie Naar, Christyenne L Bond, Henna Budhwani, Janet M Turan
{"title":"HIV and intersectional stigma among people living with HIV and healthcare workers and antiretroviral therapy adherence in the Dominican Republic.","authors":"Jelani Kerr, Ibrahim Yigit, Dustin M Long, Robert Paulino-Ramírez, John Waters, Jiaying Hao, Laura Nyblade, Nelson Varas-Díaz, Sylvie Naar, Christyenne L Bond, Henna Budhwani, Janet M Turan","doi":"10.1177/09564624241259801","DOIUrl":"10.1177/09564624241259801","url":null,"abstract":"<p><strong>Background: </strong>HIV-related stigma, discrimination, and social marginalization undermines optimal HIV care outcomes. More research examining the impact of HIV-related stigma, discrimination, other interlocking forms of oppression, and antiretroviral therapy (ART) adherence is needed to optimize HIV treatment programming. This study uses data from two clinics in the Dominican Republic to examine client and healthcare worker (HCW) perceptions of HIV and intersectional stigmas among people living with HIV.</p><p><strong>Methods: </strong>Surveys exploring demographics, HIV-related stigma, various dimensions of discrimination (race/ethnicity, HIV status, sexual orientation), healthcare engagement, and medication adherence were collected from 148 clients and 131 HCWs. Analysis of variance was conducted to examine differences in stigma by clinic and logistic regressions were used to determine predictors of optimal client medication adherence.</p><p><strong>Results: </strong>Perceived discrimination in healthcare facilities due to clients' sexual orientation retained significance in crude and multivariable logistic regression models and was negatively associated with ART adherence (aOR:0.79; 95% CI:0.66, 0.95).</p><p><strong>Discussion: </strong>Findings highlight the importance of implementing strategies to address stigma, discrimination, and social marginalization, particularly within healthcare facilities.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transactional sex and risky sexual practices in Jamaica. 牙买加的性交易和危险性行为。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-08-02 DOI: 10.1177/09564624241267333
Christina G Silvera, Sharlene Jarrett, Nicola Skyers
{"title":"Transactional sex and risky sexual practices in Jamaica.","authors":"Christina G Silvera, Sharlene Jarrett, Nicola Skyers","doi":"10.1177/09564624241267333","DOIUrl":"10.1177/09564624241267333","url":null,"abstract":"<p><strong>Background: </strong>Transactional sex relationships (TSRs) create financial and emotional support for men and women, as well as an increased sexual risk. Studies have reported high HIV and STI transmission rates among young women in transactional sex relationships. However, little is known about TSR prevalence in Jamaica and risky sexual practices among participants. This study investigates the sexual behaviour of Jamaicans in TSR.</p><p><strong>Methods: </strong>Secondary data analysis of a national survey revealed that 586 participants (38%) self-reported being in at least one TSR in the last 12 months. We also identified a third category called \"Benefluids\", who play both roles of benefactor and beneficiary in transactional sex relationships.</p><p><strong>Results: </strong>59 percent of male Benefluids had two to five transactional sex relationship partners in the last 12 months, compared to 40% of female Benefluids. Twenty-eight percent of female Benefluids reported sexually transmitted infection symptoms in the last 12 months compared to 13.5% of male Benefluids. While females reported more sexually transmitted infection symptoms, young men had the highest sexual risk precursors.</p><p><strong>Conclusions: </strong>People in transactional sex relationships often play the role of beneficiaries and benefactors to meet material and sexual needs but this increases the risk of STI symptoms.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141878733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Assessing and improving the quality of guideline-adherent hepatitis B virus care in people with HIV: A cross-sectional study. 评估和提高HIV感染者遵循指南的乙型肝炎病毒护理质量:一项横断面研究。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2023-09-20 DOI: 10.1177/09564624231203735
Patrick Ga Oomen, Vincent Jp van Kraaij, Anna M Gerritsma, Frans M Verduyn Lunel, Greet J Boland, Andy Im Hoepelman, Berend J van Welzen
{"title":"Assessing and improving the quality of guideline-adherent hepatitis B virus care in people with HIV: A cross-sectional study.","authors":"Patrick Ga Oomen, Vincent Jp van Kraaij, Anna M Gerritsma, Frans M Verduyn Lunel, Greet J Boland, Andy Im Hoepelman, Berend J van Welzen","doi":"10.1177/09564624231203735","DOIUrl":"10.1177/09564624231203735","url":null,"abstract":"<p><p>The increasing use of non-tenofovir containing antiretroviral regimens calls for renewed attention to the prevention and management of hepatitis B virus (HBV) in people with HIV (PWH). We retrospectively assessed adherence to HBV guidelines, including complete HBV screening in PWH. In people with HIV/HBV co-infection, this included HBV therapy, screening for hepatitis delta virus (HDV) and on-therapy virologic response monitoring. HIV/HBV co-infection in PWH was defined as the presence of hepatitis B surface antigen (HBsAg) at the last measurement before study entry or detectable HBV-DNA for ≥6 months. After assessment, missing laboratory tests were performed to optimize HBV monitoring and screening for co-infections. Of all PWH under follow-up, 1484/1633 (90.9%) were adequately screened for HBV. After performing missing screening tests, 466 of 1618 PWH with complete screening results (28.8%) were non-immune for HBV infection. Fifty-one (3.2%) with HIV/HBV co-infection were identified. HBV treatment was adequate in 51/51 (100%). Screening for hepatitis A, C and delta virus antibodies and fibrosis was performed in 51/51 (100%), 49/51 (96.1%), 17/51 (35.3%) and 38/51 (74.5%). Annual HBV-DNA or HBsAg monitoring was done in 18/51 (35.3%) and hepatocellular carcinoma (HCC) surveillance in 2/9 (22.2%) of those indicated. Additional testing in those with missing data identified 4/34 (11.8%) persons with HDV antibodies and 3/30 (10%) with HBsAg seroclearance. Our study demonstrates the feasibility and added value of evaluating HBV care components and performing missing laboratory tests, identifying a large number of HBV vaccination candidates and HDV antibody screening, HBsAg monitoring and HCC surveillance as key areas for improvement.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41122067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Prevalence of sarcopenia among people living with HIV defined by the revised European working group on sarcopenia in older people. 欧洲老年人肌肉疏松症工作组修订版界定的艾滋病毒感染者肌肉疏松症患病率。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-07-21 DOI: 10.1177/09564624241262549
Jasmin Jäger, Leonie Callensee, Sarah Albayrak-Rena, Stefan Esser, Oliver Witzke, Andreas Schönfeld
{"title":"Prevalence of sarcopenia among people living with HIV defined by the revised European working group on sarcopenia in older people.","authors":"Jasmin Jäger, Leonie Callensee, Sarah Albayrak-Rena, Stefan Esser, Oliver Witzke, Andreas Schönfeld","doi":"10.1177/09564624241262549","DOIUrl":"10.1177/09564624241262549","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is a progressive and systemic skeletal muscle disorder associated with an increased risk of hospitalization and adverse effects on survival. This study aims to investigate the prevalence and related risk factors of sarcopenia in people living with HIV using the revised European Working Group on Sarcopenia in Older People (EWGSOP2) definition.</p><p><strong>Methods: </strong>This cross-sectional study comprising 379 patients with confirmed HIV infection evaluated the appendicular skeletal muscle mass by employing the bioelectrical impedance analysis method. Muscle strength and functional mobility were analyzed using the five-time sit-to-stand test and the timed \"Up and Go\" test.</p><p><strong>Results: </strong>The prevalence rates of pre-sarcopenia and sarcopenia among people living with HIV were 3.4 % and 2.1 % according to the revised EWGSOP2 definition. Advanced age (Odds Ratio 1.07, <i>p</i> = .03), lower body mass index (Odds Ratio 0.79, <i>p</i> = .012) and CD4<sup>+</sup> T-cell count below 500/μl (Odds Ratio 2.22, <i>p</i> = .007) were identified as significant factors associated with sarcopenia. Sarcopenia was also identified as a significant correlate of frailty (<i>p</i> < .001).</p><p><strong>Conclusion: </strong>This is the first study examining the prevalence of sarcopenia in people living with HIV according to the revised EWGSOP2 clinical algorithm. Advanced age, lower body mass index and a poor immune status are determined as promoting factors of sarcopenia. Sarcopenia significantly correlates with frailty. Standardized clinical algorithms are essential for reliable sarcopenia diagnosis in people living with HIV in order to promote intervention strategies and to prevent adverse health outcomes.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141734094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Addressing stigma, enhancing social support and improving mental health among men who have sex with men in the Philippines. 解决菲律宾男男性行为者的污名化问题,加强社会支持,改善心理健康。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-07-20 DOI: 10.1177/09564624241264324
Rowalt Alibudbud
{"title":"Addressing stigma, enhancing social support and improving mental health among men who have sex with men in the Philippines.","authors":"Rowalt Alibudbud","doi":"10.1177/09564624241264324","DOIUrl":"10.1177/09564624241264324","url":null,"abstract":"","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141731199","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Treatment patterns and preferences of people living with HIV starting or switching antiretroviral therapy: Real-world evidence from Portugal. 开始或转换抗逆转录病毒疗法的艾滋病毒感染者的治疗模式和偏好:来自葡萄牙的真实证据。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-07-25 DOI: 10.1177/09564624241263122
Liliana Pedro, Alexandra Zagalo, Raquel Tavares, Patrícia Pacheco, Joaquim Oliveira, Inês Vaz Pinto, Rosário Serrão, Sandra Tavares, Paula Brito, Fernando Maltez, Isabel Neves, Alexandre Carvalho, Eugénio Teófilo, Joana Almeida, Inês Lains
{"title":"Treatment patterns and preferences of people living with HIV starting or switching antiretroviral therapy: Real-world evidence from Portugal.","authors":"Liliana Pedro, Alexandra Zagalo, Raquel Tavares, Patrícia Pacheco, Joaquim Oliveira, Inês Vaz Pinto, Rosário Serrão, Sandra Tavares, Paula Brito, Fernando Maltez, Isabel Neves, Alexandre Carvalho, Eugénio Teófilo, Joana Almeida, Inês Lains","doi":"10.1177/09564624241263122","DOIUrl":"10.1177/09564624241263122","url":null,"abstract":"<p><strong>Background: </strong>There is a lack of up-to-date real-life evidence on antiretroviral therapy (ART) strategies among people living with HIV (PLWH) in Portugal. This study aimed to describe the treatment strategy used in PLWH either initiating or switching ART.</p><p><strong>Methods: </strong>Non-interventional, cross-sectional, multicenter study carried out between December 2019 and October 2021 in Portugal.</p><p><strong>Results: </strong>A total of 237 PLWH were included in this study, 171 of whom were ART-experienced and 66 were ART-naïve. The study showed that triple regimens were the most common ART strategy and integrase strand transfer inhibitors-based therapy was the most frequently used therapeutic class in both ART-naïve and ART-experienced PLWH. Nevertheless, about a third of PLWH who started a triple regimen transitioned to a dual regimen. Patient-reported outcomes revealed high HIV literacy and similar ART preferences in both groups.</p><p><strong>Conclusions: </strong>This real-world study showed that triple regimens were the most widely used ART strategy, even after the European AIDS Clinical Society guidelines introduced the recommendation of a dual regimen for naïve patients. The cohorts of this study presented a high level of HIV literacy at the time of inclusion. Our findings highlighted that taking pills only once a day is considered a very important feature for most patients.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141758684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increase in congenital syphilis in a tertiary-care centre from Madrid, Spain: Back to the classics. 西班牙马德里一家三级医疗中心先天性梅毒病例的增加:回归经典。
IF 1.4 4区 医学
International Journal of STD & AIDS Pub Date : 2024-10-01 Epub Date: 2024-07-22 DOI: 10.1177/09564624241264581
Alfredo Maldonado-Barrueco, Claudia Sanz-González, Iker Falces-Romero, Almudena Gutiérrez-Arroyo, Dolores Montero-Vega, Inmaculada Quiles-Melero
{"title":"Increase in congenital syphilis in a tertiary-care centre from Madrid, Spain: Back to the classics.","authors":"Alfredo Maldonado-Barrueco, Claudia Sanz-González, Iker Falces-Romero, Almudena Gutiérrez-Arroyo, Dolores Montero-Vega, Inmaculada Quiles-Melero","doi":"10.1177/09564624241264581","DOIUrl":"10.1177/09564624241264581","url":null,"abstract":"<p><p>Globally, an increase in sexually transmitted diseases worldwide has been reported, including acquired <i>Treponema pallidum</i> infection. Congenital syphilis is the mother-to-child transmission syphilis infection, experiencing an increase in cases returning to incidence rates of years ago. We report three cases of symptomatic congenital syphilis occurring in a tertiary-care hospital in Madrid (Spain). Cases were diagnosed by serology and molecular biology methods. The use of molecular techniques in specimens such as skin lesion, subplacental exudate swabs, bronchoalveolar aspirate, or cerebrospinal fluid could favour the diagnosis of this clinical entity, especially in symptomatic newborns with systemic involvement.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141748100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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