International Journal of STD & AIDS最新文献

Role of sociodemographic characteristics on self-stigma among young MSM living with HIV in Yogyakarta, Indonesia: A cross-sectional study. 印度尼西亚日惹感染艾滋病毒的年轻男男性行为者的社会人口特征对自我污名化的影响：横断面研究。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-07 DOI: 10.1177/09564624241288286

Alessandro Alfieri, Nurwestu Rusetiyanti, Devi Artami Susetiati, Sunardi Radiono, Carla Raymondalexas Marchira, Satiti Retno Pudjiati

{"title":"Role of sociodemographic characteristics on self-stigma among young MSM living with HIV in Yogyakarta, Indonesia: A cross-sectional study.","authors":"Alessandro Alfieri, Nurwestu Rusetiyanti, Devi Artami Susetiati, Sunardi Radiono, Carla Raymondalexas Marchira, Satiti Retno Pudjiati","doi":"10.1177/09564624241288286","DOIUrl":"10.1177/09564624241288286","url":null,"abstract":"Background: Our study aimed to determine the role of sociodemographic characteristics on self-stigma among young men who have sex with men (MSM) living with HIV in Yogyakarta, Indonesia.Methods: This cross-sectional observational study was conducted from August-November 2022. Participants were recruited from outpatient clinics at Dr. Sardjito, Yogyakarta, Indonesia. The Indonesian version of the Berger HIV Stigma Scale measured self-stigma. The statistical analysis utilized a 95% confidence level and determined significance by p-values <0.05.Results: 72 young MSM were enrolled and completed questionnaires assessing sociodemographic and self-stigma. The average self-stigma score was 98.97. Education level was significantly associated with severe self-stigma in the bivariate analysis (p < .05). In the multivariate analysis, those with higher levels of education were significantly more likely to experience severe self-stigma (r = 2.938, p < .05). Employment status, family support, and education level were significantly associated with increased concerns in the disclosure, negative self-image, and public attitudes subscales (all p < .05).Conclusions: The results demonstrate associations between sociodemographic and self-stigma levels among young MSM living with HIV in Yogyakarta, Indonesia. Further research regarding the educational level, employment status, and family support that can influence the perception and quality of life of PLHIV may need to be carried out.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"72-79"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between motor neuron disease and HIV infection: A systematic review of case reports. 运动神经元疾病与艾滋病病毒感染之间的关联：病例报告的系统回顾。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241288283

João Paulo Moreira Fernandes, Leonardo Peixoto Garcia, Felipe Araújo Gouhie, Raquel Campos Pereira, Diogo Fernandes Dos Santos

{"title":"Association between motor neuron disease and HIV infection: A systematic review of case reports.","authors":"João Paulo Moreira Fernandes, Leonardo Peixoto Garcia, Felipe Araújo Gouhie, Raquel Campos Pereira, Diogo Fernandes Dos Santos","doi":"10.1177/09564624241288283","DOIUrl":"10.1177/09564624241288283","url":null,"abstract":"Background: Motor neuron disease (MND) is a well-known group of neurodegenerative diseases, with amyotrophic lateral sclerosis (ALS) being the most common form. Since 1985, a possible association between MND/ALS and HIV infection has been described.Methods: We performed a systematic review of case reports and case series involving people living with HIV with MND/ALS through PubMed, Bireme, Embase, and Lilacs databases. The risk of bias was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Tool for Case Reports.Results: We analyzed 36 articles presenting 88 cases. The mean age was 41.6 years. Antiretroviral therapy (ART) was used by 89.8% and riluzole by 16.9%. First signs and symptoms were similarly present on cervical/upper (25%) and lumbosacral/lower limbs (23.9%), mostly with fasciculations (69.8%) and hyperreflexia (58.8%). MND had a progressive course in 32.9% patients and a clinical improve in 54.6% following ART. The mean survival of the 32 patients who died was 12.3 months and the mean survival of the living patients was 62 months. Respiratory failure was the main cause of death (35.7%).Conclusions: MND/ALS may present differently in the people living with HIV as a rapidly progressive disease in younger people but with the potential to improve weakness and survival through antiretroviral therapy.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"24-35"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Implementation of a multidisciplinary approach to care for people with HIV aged 80 years and over. 对 80 岁及以上的艾滋病毒感染者实施多学科护理方法。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-09-30 DOI: 10.1177/09564624241286558

Maithili Varadarajan, Sophie Blackburn, Nicolo Girometti, Alexandra Hicks, Elizabeth Senkoro, Caterina Candela, Elizabeth Ridsdill Smith, Nadia Naous, Timothy Tong, Marta Boffito

{"title":"Implementation of a multidisciplinary approach to care for people with HIV aged 80 years and over.","authors":"Maithili Varadarajan, Sophie Blackburn, Nicolo Girometti, Alexandra Hicks, Elizabeth Senkoro, Caterina Candela, Elizabeth Ridsdill Smith, Nadia Naous, Timothy Tong, Marta Boffito","doi":"10.1177/09564624241286558","DOIUrl":"10.1177/09564624241286558","url":null,"abstract":"Background: Frailty adversely affects health and quality of life of people with HIV (PWH). A multidisciplinary-team (MDT) was established to perform a Comprehensive Geriatric Assessment (CGA) and to address modifiable risk factors in elderly PWH.Methods: PWH aged over 80 years were reviewed by a dedicated HIV/geriatric clinic at Chelsea and Westminster Hospital. Descriptive statistics were used to report the variables of interest.Results: Sixty-three PWH were reviewed, with a median age of 82 (IQR 80-86). Fifty-seven (88%) were men. The median number of co-morbidities was five (IQR 4-7) and polypharmacy was seen in 55 (85%), with a median of six (IQR 5-8) co-medications reported. The median Rockwood Clinical Frailty Score was two (IQR 2-5). Antiretrovirals were modernised in 18 (29%) individuals; co-medication changes and de-prescribing was recommended in 39 (62%).Conclusion: A MDT approach helped reducing polypharmacy and frailty, suggesting that specialised tools and MDT input are key to identify medical and social concerns in elderly PWH.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"65-71"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346762","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Incidence of non-alcoholic fatty liver disease in antiretroviral therapy-naïve people with human immunodeficiency virus who start DTG/ABC/3TC compared to BIC/FTC/TAF at 48-week follow-up. 开始接受 DTG/ABC/3TC 与 BIC/FTC/TAF 抗逆转录病毒治疗的人类免疫缺陷病毒感染者在 48 周随访期间的非酒精性脂肪肝发病率比较。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-09-27 DOI: 10.1177/09564624241287886

Ana Luz Cano Díaz, Salma Triana González, Gloria Elizabeth Salinas Velázquez, José Antonio Mata Marín, Jesús Enrique Gaytán Martínez, Stefan Mauss

{"title":"Incidence of non-alcoholic fatty liver disease in antiretroviral therapy-naïve people with human immunodeficiency virus who start DTG/ABC/3TC compared to BIC/FTC/TAF at 48-week follow-up.","authors":"Ana Luz Cano Díaz, Salma Triana González, Gloria Elizabeth Salinas Velázquez, José Antonio Mata Marín, Jesús Enrique Gaytán Martínez, Stefan Mauss","doi":"10.1177/09564624241287886","DOIUrl":"10.1177/09564624241287886","url":null,"abstract":"Purpose: To determine the incidence of non-alcoholic fatty liver disease (NAFLD) by non-invasive methods in people living with HIV (PLWH).Methods: Prospective cohort, in PLWH naïve to antiretroviral therapy, starting bictegravir (BIC) or dolutegravir (DTG) at the Hospital de Infectología \"La Raza\", in Mexico City, from February 2021 to August 2023. We measured at baseline and 48 weeks triglycerides and glucose index (TyG), fatty liver index (FLI), hepatic steatosis index (HSI) and liver ultrasonography; relative risk (RR) for developing NAFLD was determined.Results: At 48 weeks, TyG index in BIC-group 4.54 (IQR 4.36-4.75), in DTG-group 4.66 (IQR 4.49-4.80), p = .080; HSI in BIC-group 30.30 (IQR 28.12-33.70), in DTG-group 30.85 (IQR 28.02-34.50), p = .650; FLI in BIC-group 14.88 (IQR 7.91-31.80), in DTG-group 19.49 (IQR 8.49-32.28), p = .729; NAFLD was detected by US in 6 [10.3% (95%CI 4.8%-20.7%)] in BIC-group and, 7 [10.9% (95%CI 6.4%-20.9%)] in DTG-group, p = .916. Risk factors for NAFLD development were baseline BMI ≥25 kg/m2, baseline HDL-c <40 mg/dL, and FIB-4 >1.3 at 48 weeks.Conclusion: There is a high incidence of NAFLD in PLWH who start a second generation INSTI at 48 weeks; baseline overweight, low HDL-cholesterol and FIB-4 >1.3 at 48 weeks of treatment were independent risk factors for NAFLD development.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"36-41"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346763","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Game of clades: A global mpox snapshot. 支系游戏：全球 mpox 快照。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-09-26 DOI: 10.1177/09564624241288279

Muhammad Abbas Abid

引用次数: 0

Lipschütz ulcers: A diagnosis to be considered in the post-COVID-19 era. Lipschütz溃疡：后 COVID-19 时代需要考虑的诊断。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241289993

Rodríguez-Hernández Fernando Daniel, Pérez-Cavazos Samantha, Camacho-Ortiz Adrián, Treviño-Salinas Emilio Modesto, Pérez-Barragán Edgar

引用次数: 0

Sexual and domestic violence enquiry: A national exploratory survey of asking and telling in sexual health services in the UK. 性暴力和家庭暴力调查：对英国性健康服务中的询问和倾诉进行全国性探索调查。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-09-26 DOI: 10.1177/09564624241286926

Jane Meyrick, Amy Bennett, Kyle McGovern, Charlotte Kite

{"title":"Sexual and domestic violence enquiry: A national exploratory survey of asking and telling in sexual health services in the UK.","authors":"Jane Meyrick, Amy Bennett, Kyle McGovern, Charlotte Kite","doi":"10.1177/09564624241286926","DOIUrl":"10.1177/09564624241286926","url":null,"abstract":"Background: Gender-based violence in the form of domestic and sexual abuse represent a worldwide public health and civil rights issue. Healthcare and sexual health have a central role to play in prevention, particularly in the identification of sexual and domestic violence/abuse within a frontline service in which it often presents. Survivors of sexual violence and abuse commonly pass through sexual health services without being asked about their victimisation. Healthcare should be able to identify survivors, provide first line support, refer to specialist services and link to comprehensive post assault care.Methods: In the first joint study of its kind, the Univeristy of the West of England worked with the British Association for Sexual Health and HIV (BASHH) and their Sexual Violence Specialist Interest Group (SVSIG). We report the findings of a snapshot, non-probability, exploratory survey of current comparative sexual and domestic violence/abuse enquiry practice in Genito Urinary Medicine services across the UK.Results: Sixty-two responding services evidenced variable practice around asking, collating data, referral, training and staff supervision.Conclusions: This benchmarking study of practice in the UK sets a bar against which all services can measure and improve current practice on gender-based violence identification, a crucial role of sexual health services in reducing the inequalities driven harm of undisclosed trauma.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"42-46"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346766","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical characteristics and mortality of tuberculosis among adults living with HIV/AIDS: A single center, retrospective cohort study in Thailand. 感染艾滋病毒/艾滋病的成年人中结核病的临床特征和死亡率：泰国单中心回顾性队列研究。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241289986

Hariwong Chaicharoen, Sethapong Lertsakulbunlue, Boonsub Sakboonyarat, Worapong Nasomsong

{"title":"Clinical characteristics and mortality of tuberculosis among adults living with HIV/AIDS: A single center, retrospective cohort study in Thailand.","authors":"Hariwong Chaicharoen, Sethapong Lertsakulbunlue, Boonsub Sakboonyarat, Worapong Nasomsong","doi":"10.1177/09564624241289986","DOIUrl":"10.1177/09564624241289986","url":null,"abstract":"Background: Tuberculosis (TB) among people living with HIV/AIDS (PLWHA) contributes substantially to morbidity and mortality, particularly in high TB burden countries. Our objective is to investigate the clinical characteristics and mortality rates associated with TB among adult PLWHA over a 10-year period at an urban HIV clinic situated in a high TB burden country.Method: A retrospective cohort study was conducted in 2022. The primary endpoints were clinical characteristics and mortality rate of TB, determined as per 100 person-years among adult PLWHA, presented with a 95% confidence interval. Univariable and multivariable Cox proportional regression analyses were performed to determine risk factors for TB mortality.Result: From January 2012-December 2022, 155 PLWHA receiving a diagnosis of TB were enrolled. The median age was 29 (26.5-48.5) years, and the median CD4 + T cell count was 141 (41.8-252.8) cells/µL, with 60.0% of patients with TB manifesting as disseminated infection. The most involved organs were pulmonary (89.7%), lymph nodes (39.4%) and pleura (14.8%). The treatment outcomes exhibited success in 63.2% of cases, relapse in 5.2%, loss to follow up in 17.4% and death in 14.2%. The overall mortality rate was 18.8 per 100 person-years. Multivariable analyses showed significant factors affecting mortality, including lymph node involvement (adjusted HR 3.5; 95% CI 1.1-10.8) and thrombocytopenia (adjusted HR 74.2; 95% CI 10.0-551.4).Conclusion: TB in PLWHA, commonly presenting as disseminated infection, contributes to high mortality. Lymph node involvement and thrombocytopenia are significant factors contributing to mortality. Tuberculosis preventive treatment should be considered for improved prevention strategies among PLWHA, particularly in high TB burden countries.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"56-64"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Joint British Association for Sexual Health and HIV and Royal College of Obstetricians and Gynaecologists national UK guideline for the management of herpes simplex virus (HSV) in pregnancy and the neonate (2024 update). 英国性健康与艾滋病协会和英国皇家妇产科医学院联合制定的英国国家妊娠期和新生儿单纯疱疹病毒 (HSV) 管理指南（2024 年更新）。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-09-30 DOI: 10.1177/09564624241280734

Emily Clarke, Raj Patel, Dyan Dickins, Katy Fidler, Allan Jackson, Margaret Kingston, Christine Jones, Hermione Lyall, Marian Nicholson, Emanuela Pelosi, David Porter, Gemma Powell, Elizabeth Foley

引用次数: 0

Characterizing long-acting injectable antiretroviral therapy eligibility and initiation at a safety net academic medical center in the southeastern United States. 美国东南部一家安全网学术医疗中心的长效注射抗逆转录病毒疗法资格和启动特点。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241289998

Sarah E Rutstein, Christopher Lopez, Thibaut Davy-Mendez, Harsh Agarwal, Hanna Huffstetler, Angela Perhac, Barbarajean Turner, Joseph J Eron, Vivian Go, Claire E Farel, Kuo-Ping Li, Sonia Napravnik

{"title":"Characterizing long-acting injectable antiretroviral therapy eligibility and initiation at a safety net academic medical center in the southeastern United States.","authors":"Sarah E Rutstein, Christopher Lopez, Thibaut Davy-Mendez, Harsh Agarwal, Hanna Huffstetler, Angela Perhac, Barbarajean Turner, Joseph J Eron, Vivian Go, Claire E Farel, Kuo-Ping Li, Sonia Napravnik","doi":"10.1177/09564624241289998","DOIUrl":"10.1177/09564624241289998","url":null,"abstract":"Background: Long-acting injectable (LAI) cabotegravir/rilpivirine (CAB/RPV) extends dosing intervals from daily to every 8 weeks. Equitable implementation requires anticipating and addressing barriers to use. We described LAI-CAB/RPV eligibility and initiation among persons with HIV (PWH) receiving care at a Southeastern US academic medical center. Methods: We included PWH ≥18 years, in care 01/01/2020-12/31/2021, and participating in the UNC CFAR HIV Clinical Cohort. We characterized LAI-CAB/RPV eligibility, compared those with and without recent detectable viral load (VL), and described clinical outcomes on LAI-CAB/RPV. Results: Among 1672 PWH, 425 (25.4%) had LAI-CAB/RPV drug-resistance. Among 1238 LAI-eligible PWH, 8.9% had detectable VL. Median age was 53 (interquartile range 40, 61), 54.6% were non-Hispanic Black, and 73.6% male. Over one-third lived >50 miles from clinic, one-fifth were uninsured, and 7.4% reported hazardous alcohol use. Gaps in care (prior 12-month) were more common among PWH with detectable VL versus suppressed (23.1% vs 13.9%, p = 0.03). 6/47 initiated LAI-CAB/RPV had detectable VL prior to injection; >95% sustained suppression and those with detectable VL had a rapid decline in viremia. Conclusions: Three-quarters of PWH were eligible for LAI-CAB/RPV, but equitable implementation may require addressing challenges such as distance to care, inconsistent care engagement, and other comorbid conditions, particularly for PWH with viremia.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"47-55"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0