International Journal of STD & AIDS最新文献

Unusual, gigantic cystic echinococcosis in a woman living with HIV. 一名携带HIV病毒的妇女患有罕见的巨大囊性包虫病。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-24 DOI: 10.1177/09564624251362094

Khouloud Mnif, Amani Bouabdallah, Tarak Ben Jemaa, Emna Elleuch, Sami Fendri, Boussayma Hammami, Zeineb Mnif, Salah Boujelben, Chakib Marrakchi, Mounir Ben Jemaa

{"title":"Unusual, gigantic cystic echinococcosis in a woman living with HIV.","authors":"Khouloud Mnif, Amani Bouabdallah, Tarak Ben Jemaa, Emna Elleuch, Sami Fendri, Boussayma Hammami, Zeineb Mnif, Salah Boujelben, Chakib Marrakchi, Mounir Ben Jemaa","doi":"10.1177/09564624251362094","DOIUrl":"https://doi.org/10.1177/09564624251362094","url":null,"abstract":"IntroductionCystic echinococcosis, or hydatidosis, is a parasite infection that can occur in humans. It can affect all organs, mostly the liver and the lungs. The number, size and evolution of those cysts is mediated by the immune system. Herein we report an unusual presentation of hydatidosis in an immunocompromised woman who lives with HIV.Case presentationOur patient was a 40-year-old female with a 2-decade history of HIV and echinococcal infection. She was in AIDS stage due to poor medical adherence. She presented a medullar toxicity to Albendazole, a medication she had been taking for years to control the echinococcal cysts, which were stable then. Upon stopping the Albendazole, she presented an enlargement of those cysts. Surgery was mandatory, and revealed five liver cysts, a 12cm-large kidney cyst, and a gigantic 20 cm-large retroperitoneal cyst. They were treated successfully, and the patient has been asymptomatic during the last 4 years since surgery, along with maintained HIV suppression.ConclusionHydatidosis can be negatively affected by immunosuppression such as HIV infection. However, the scarcity of the cases studying this association makes it difficult to fully grasp the possible interactions between those two diseases.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251362094"},"PeriodicalIF":1.4,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698527","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemophagocytic lymphohistiocytosis syndrome (HLH) in HIV-associated Kaposi sarcoma patients: The first case series from a single center in Türkiye. hiv相关卡波西肉瘤患者的噬血细胞淋巴组织细胞增多综合征（HLH）：来自<s:1> rkiye单一中心的第一个病例系列。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-23 DOI: 10.1177/09564624251355834

Zarifa Orta, Aysun Benli, Arif Atahan Çağatay, Seniha Başaran, Simge Erdem, Sevgi Beşişik

{"title":"Hemophagocytic lymphohistiocytosis syndrome (HLH) in HIV-associated Kaposi sarcoma patients: The first case series from a single center in Türkiye.","authors":"Zarifa Orta, Aysun Benli, Arif Atahan Çağatay, Seniha Başaran, Simge Erdem, Sevgi Beşişik","doi":"10.1177/09564624251355834","DOIUrl":"https://doi.org/10.1177/09564624251355834","url":null,"abstract":"BackgroundKaposi sarcoma in people living with HIV and AIDS usually involves slowly progressive skin lesions. Cases of Kaposi sarcoma complicated by hemophagocytic lymphohistiocytosis are rare. In this report, we present the first series of hemophagocytic lymphohistiocytosis cases from Türkiye associated with AIDS and Kaposi sarcoma.MethodsCases of hemophagocytic lymphohistiocytosis in people living with HIV and AIDS and Kaposi sarcoma who met the HLH-2004 diagnostic criteria recommended by the \"Histiocyte Society\" were included in the study. The patient's demographic, clinical, and laboratory characteristics were recorded retrospectively.ResultsFour patients presented with fever, cytopenia, peripheral lymphadenomegaly, splenomegaly, and hepatomegaly. Fever persisted throughout their hospitalization. At the time of HLH diagnosis, Kaposi sarcoma was detected in the lymph node biopsies of one patient and in the skin biopsies of three patients. Hemophagocytosis was observed in bone marrow aspirations from all patients. Three patients received dexamethasone and etoposide for hemophagocytic lymphohistiocytosis treatment, while one received dexamethasone alone. All four patients died.ConclusionsCases of hemophagocytic lymphohistiocytosis associated with Kaposi sarcoma and AIDS are rare in the literature. In conclusion, high fever may appear in the early stages of Kaposi sarcoma in people living with HIV and AIDS. Since hemophagocytic lymphohistiocytosis has a high mortality rate, early diagnosis and prompt initiation of appropriate treatment are crucial.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251355834"},"PeriodicalIF":1.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

HIV prevalence and associated risk factors among people who inject drugs in four states of central India: Findings from the 17th round of HIV sentinel surveillance. 印度中部四个邦注射吸毒者中的艾滋病毒流行情况及相关风险因素：来自第17轮艾滋病毒哨点监测的结果。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-23 DOI: 10.1177/09564624251355835

Shreya Jha, Nishakar Thakur, Lukram Slim, Sanjay Rai, Pradeep Kumar, Puneet Misra, Rakesh Kumar, Partha Haldar, Chinmoyee Das

{"title":"HIV prevalence and associated risk factors among people who inject drugs in four states of central India: Findings from the 17th round of HIV sentinel surveillance.","authors":"Shreya Jha, Nishakar Thakur, Lukram Slim, Sanjay Rai, Pradeep Kumar, Puneet Misra, Rakesh Kumar, Partha Haldar, Chinmoyee Das","doi":"10.1177/09564624251355835","DOIUrl":"https://doi.org/10.1177/09564624251355835","url":null,"abstract":"BackgroundThis study was conducted to assess the prevalence of HIV and its associated risk factors among people who inject drugs in the four states of Central Zone of India (Bihar, Delhi, Uttar Pradesh and Uttarakhand), based on the data collected during the 17th round of HIV Sentinel Surveillance (HSS) during January to March, 2020.MethodsThe data was used from the 17th round of HSS which was collected through a paper-based survey among participants who were identified as people who inject drugs (PWIDs), followed by blood sample collection. Random sampling method was used to identify 250 PWIDs from each sentinel site.ResultsThe key demographic findings show that 60.1% of the participants were of age >=30 years and primarily urban residents (84.5%). Most participants have been tested for HIV previously (97.5%). With almost two-thirds of the participants injecting drugs daily, 89.5% of them reported to have used sterile needles each time. One-third of the participants had avoided health care services due to stigma and discrimination and they are significantly at higher odds of being HIV seropositive (1.83 times).ConclusionsThe study highlights the risk behaviour association with higher odds of being HIV seropositive were high risk occupation, sharing of needles, PWIDs on OST therapy, HIV testing and avoidance of healthcare services - due to stigma. Better programmatic approach is needed to protect the PWIDs.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251355835"},"PeriodicalIF":1.4,"publicationDate":"2025-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

British association of sexual health and HIV national guideline for the management of infection with Mycoplasma genitalium, 2025. 英国性健康和艾滋病毒协会生殖器支原体感染管理国家指南，2025年。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-17 DOI: 10.1177/09564624251359054

Suneeta Soni, Helen Fifer, Yaser Al-Shakarchi, Joanne Bassett, Joy Mbaulu, Nicolas Pinto-Sander, Sara Strodtbeck, Michael Rayment

引用次数: 0

Number of chlamydia diagnoses per capita not associated with rates of ectopic pregnancies and female infertility - An ecological study. 衣原体诊断的人均数量与异位妊娠率和女性不孕症无关-生态学研究。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-15 DOI: 10.1177/09564624251361294

Vanbaelen Thibaut, Sheeba Manoharan-Basil, Kenyon Chris

{"title":"Number of chlamydia diagnoses per capita not associated with rates of ectopic pregnancies and female infertility - An ecological study.","authors":"Vanbaelen Thibaut, Sheeba Manoharan-Basil, Kenyon Chris","doi":"10.1177/09564624251361294","DOIUrl":"https://doi.org/10.1177/09564624251361294","url":null,"abstract":"BackgroundTubal infertility and ectopic pregnancies are serious, but rare, complications of chlamydia infections. It is unclear whether chlamydia screening in women has an impact on these complications. Chlamydia incidence rates between European countries vary by orders of magnitude, which largely reflects different intensities of screening.MethodsWe used chlamydia diagnoses rates as a proxy for chlamydia screening rates to assess if differences in screening intensity were associated with differences in the frequency of ectopic pregnancy and the prevalence of infertility in women. We used mixed effects linear regression to assess for an association between chlamydia screening intensity in European countries and two outcomes: (1) the incidence of ectopic pregnancy and (2) the prevalence of infertility in women, while controlling for year, income and quality of health services.ResultsThe number of countries with available data increased from 3 in 1990 to 23 in 2019, before slightly declining to 22 in 2020. CT incidence varied across countries, from a median of 207 cases per 100,000 in 1990 (IQR: 59-313) to 33 cases per 100,000 in 2021 (IQR: 3-179). There was less variation in ectopic pregnancy incidence (median: 208 and 33 per 100,000 in 1990 and 2021, respectively), and female infertility prevalence (median 1,224 and 1,587 per 100,000 in 1990 and 2021, respectively). No association was found between screening intensity and ectopic pregnancy incidence or infertility prevalence after adjusting for year, GDP per capita, and universal health coverage index.ConclusionsOur results are compatible with other types of data that suggest that the intensity of screening for chlamydia is not associated with a large effect on the population-level frequency of all ectopic pregnancies and female infertility.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251361294"},"PeriodicalIF":1.4,"publicationDate":"2025-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144637017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Paving the way for syphilis reverse algorithm diagnostic strategy in the Indian scenario through treponemal POCT. 通过梅毒螺旋体POCT为印度梅毒逆向算法诊断策略铺平道路。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-11 DOI: 10.1177/09564624251358285

Maitrayee Narayan, Hitender Gautam, Priyam Batra, Bimal Kumar Das

{"title":"Paving the way for syphilis reverse algorithm diagnostic strategy in the Indian scenario through treponemal POCT.","authors":"Maitrayee Narayan, Hitender Gautam, Priyam Batra, Bimal Kumar Das","doi":"10.1177/09564624251358285","DOIUrl":"https://doi.org/10.1177/09564624251358285","url":null,"abstract":"BackgroundThe global burden of syphilis has remained persistently high with globally prevalent cases of syphilis, estimated to be 49.71 million in 2019. In India, where rates of syphilis screening remain sub-optimal, an accurate point-of-care (POC) test is convenient to carry out and guide immediate treatment. Here, we sought to evaluate the performance of an indigenous rapid POC test (Syphicheck -WB).MethodsThis study was carried out in the serology laboratory of our tertiary care center over 2 months. Five hundred serum samples were chosen randomly. Performance parameters of the POC test were calculated in comparison to the Treponema pallidum hemagglutination test, which was considered the reference standard.ResultsOne hundred and six samples (21.2%) were reactive for syphilis by the reference method (TPHA). The sensitivity and specificity of the POC test, were 81.13% and 98.48% respectively. The sensitivity and specificity of the reverse algorithm using POC test for screening, were 81.13% and 99.75% respectively, and of the traditional algorithm using VDRL were 77.36% and 100% respectively.ConclusionThis POC test is a promising candidate as a rapid treponemal screening test. It is likely to improve screening for syphilis under both laboratory as well as field conditions.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251358285"},"PeriodicalIF":1.4,"publicationDate":"2025-07-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144612150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An evaluation of using community-based peer navigators for improving HIV treatment outcomes among antiretroviral therapy clients in Malawi Defence Force clinics. 利用社区同伴导路员改善马拉维国防军诊所抗逆转录病毒治疗客户的艾滋病毒治疗结果的评估。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-09 DOI: 10.1177/09564624251356052

A V Adson Nantchito, D Jimmy-Gama, Zimveka Chatsika, Chifundo Azizi, Yamikani Chinthuli, Chester Makhuwira, Gertrude Ngwata, Kingsley Magomero, Geofrey Ndekha

{"title":"An evaluation of using community-based peer navigators for improving HIV treatment outcomes among antiretroviral therapy clients in Malawi Defence Force clinics.","authors":"A V Adson Nantchito, D Jimmy-Gama, Zimveka Chatsika, Chifundo Azizi, Yamikani Chinthuli, Chester Makhuwira, Gertrude Ngwata, Kingsley Magomero, Geofrey Ndekha","doi":"10.1177/09564624251356052","DOIUrl":"https://doi.org/10.1177/09564624251356052","url":null,"abstract":"BackgroundMalawi Defence Force (MDF) implemented test-and-start strategy in 2016 to expedite initiation of antiretroviral therapy (ART) for HIV diagnosed individuals. However, key indicators for the 95-95-95 targets, namely retention and viral load suppression, remained sub optimal. To address this, MDF introduced community-based peer navigators (PNs) in 2020 to support ART adherence. We sought to assess impact of this intervention.MethodsA mixed methods study was conducted where ART programmatic data was collected retrospectively from seven MDF health facilities. The analysis compared treatment interruption (ITT), return to treatment (RTT) and viral suppression rates 18 months before and after the intervention.ResultsThe median numbers IIT and RTT was 308 (IQR = 96) and 99 (IQR = 67) pre intervention respectively, while the median IIT and RTT was 145 (IQR = 47) and 160 (IQR = 46) post intervention respectively. Treatment current increased by 36.5% through back to care (BTC) and by 10.4% through new initiations. Out of 1,073 clients due for VL flagged on patient cards, 953 (88.9%) had their blood samples taken compared to 61.8% in pre intervention period (p < 0.01).ConclusionsThe involvement of PNs led to notable improvements in program outcomes. Expanding the peer navigator model within the BTC initiative is recommended to sustain and build upon these gains.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251356052"},"PeriodicalIF":1.4,"publicationDate":"2025-07-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A constipating mass in a 12-year-old child as a result of child sex abuse. 一个12岁的孩子因为儿童性侵而便秘。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-08 DOI: 10.1177/09564624251355830

Teghveer Singh, Pooja Sharma, Reetu Agrawal, Shailendra Srivastava, Nishant Bhardwaj, Nisha Verma

引用次数: 0

Complementary and alternative medicines among people living with HIV: results from the CAMPER study. 艾滋病毒感染者的补充和替代药物：CAMPER研究的结果。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-08 DOI: 10.1177/09564624251359060

Lolita Sasset, Maria Mazzitelli, Mattia Trunfio, Angela Londero, Vincenzo Scaglione, Silvia Cavinato, Roberto Luzzati, Marina Malena, Vinicio Manfrin, Annamaria Cattelan

{"title":"Complementary and alternative medicines among people living with HIV: results from the CAMPER study.","authors":"Lolita Sasset, Maria Mazzitelli, Mattia Trunfio, Angela Londero, Vincenzo Scaglione, Silvia Cavinato, Roberto Luzzati, Marina Malena, Vinicio Manfrin, Annamaria Cattelan","doi":"10.1177/09564624251359060","DOIUrl":"https://doi.org/10.1177/09564624251359060","url":null,"abstract":"BackgroundWe analyzed the prevalence of complementary/alternative medicines (CAM) in people living with HIV (PLWH) and effects on immunovirological response, treatment adherence, and quality of life (QoL).MethodsA multicentre cross-sectional observational study involving PLWH who were stably on combination antiretroviral therapy (cART) between 2018 and 2019. Participants completed a modified International Questionnaire to Measure Use of Complementary and Alternative Medicine (I-CAM-Q). CAM use was analyzed using descriptive statistics and multivariable logistic regression models were implemented to study factors associated.ResultsCAM use (predominantly vitamins and dietary supplements: 64.2%) was reported by 38.5% of the 548 participants. Higher CAM use was noted in men who have sex with men, Caucasians, people with hepatitis C virus, and those with higher level of education. 76.3% used CAM for a better well-being, energy restoration, and aesthetic purposes. Multivariable analysis identified ethnicity, HIV acquisition route, HCV status, level of education, plasma undetectability and cardiovascular diseases as significant factors influencing CAM use. Immunovirological response, treatment adherence, and QoL were not significantly different between CAM users and non-users.ConclusionsThe study highlighted a high prevalence of CAM use in PLWH, revealing no adverse effects on treatment efficacy or clinical outcomes. Demographic factors influence CAM use, underscoring the need for healthcare providers to explore CAM use, promoting information and safe care.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251359060"},"PeriodicalIF":1.4,"publicationDate":"2025-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144591233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

In response to: "Post-acute sequelae of COVID-19 in people of Black ethnicities living with HIV in the United Kingdom" by Ottaway et al. The impact of COVID-19 lockdown on HIV care provision. 针对Ottaway等人的“英国黑人艾滋病毒感染者的COVID-19急性后后遗症”。COVID-19封锁对艾滋病毒护理提供的影响。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-07-08 DOI: 10.1177/09564624251352055

Frances Lander, Maithili Varadarajan, Silma Shah, Suleman Khan, Benedict Moore, Lea Adamson, Samuel Lubega, Hewad Ahmadzai, Yahya Ibrahim, David Asboe, Marta Boffito

引用次数: 0