利用社区同伴导路员改善马拉维国防军诊所抗逆转录病毒治疗客户的艾滋病毒治疗结果的评估。

IF 1.4 4区 医学 Q4 IMMUNOLOGY
A V Adson Nantchito, D Jimmy-Gama, Zimveka Chatsika, Chifundo Azizi, Yamikani Chinthuli, Chester Makhuwira, Gertrude Ngwata, Kingsley Magomero, Geofrey Ndekha
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引用次数: 0

摘要

马拉维国防军(MDF)于2016年实施了“测试-启动”战略,以加快对艾滋病毒诊断个体启动抗逆转录病毒治疗(ART)。然而,95-95-95靶点的关键指标,即保留率和病毒载量抑制,仍然不是最理想的。为了解决这一问题,MDF在2020年引入了基于社区的同伴导航员(PNs),以支持抗逆转录病毒治疗的依从性。我们试图评估这种干预措施的影响。方法采用混合方法进行研究,回顾性收集来自七个MDF卫生机构的ART规划数据。该分析比较了干预前后18个月的治疗中断(ITT)、恢复治疗(RTT)和病毒抑制率。结果干预前IIT和RTT的中位数分别为308 (IQR = 96)和99 (IQR = 67),干预后IIT和RTT的中位数分别为145 (IQR = 47)和160 (IQR = 46)。通过重返护理(BTC)增加了36.5%,通过新开始治疗增加了10.4%。在1073名患者卡上标记为VL的患者中,953名(88.9%)患者采集了血液样本,而干预前为61.8% (p < 0.01)。结论PNs的介入显著改善了治疗效果。建议在BTC倡议中扩展对等导航员模型,以维持和巩固这些成果。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
An evaluation of using community-based peer navigators for improving HIV treatment outcomes among antiretroviral therapy clients in Malawi Defence Force clinics.

BackgroundMalawi Defence Force (MDF) implemented test-and-start strategy in 2016 to expedite initiation of antiretroviral therapy (ART) for HIV diagnosed individuals. However, key indicators for the 95-95-95 targets, namely retention and viral load suppression, remained sub optimal. To address this, MDF introduced community-based peer navigators (PNs) in 2020 to support ART adherence. We sought to assess impact of this intervention.MethodsA mixed methods study was conducted where ART programmatic data was collected retrospectively from seven MDF health facilities. The analysis compared treatment interruption (ITT), return to treatment (RTT) and viral suppression rates 18 months before and after the intervention.ResultsThe median numbers IIT and RTT was 308 (IQR = 96) and 99 (IQR = 67) pre intervention respectively, while the median IIT and RTT was 145 (IQR = 47) and 160 (IQR = 46) post intervention respectively. Treatment current increased by 36.5% through back to care (BTC) and by 10.4% through new initiations. Out of 1,073 clients due for VL flagged on patient cards, 953 (88.9%) had their blood samples taken compared to 61.8% in pre intervention period (p < 0.01).ConclusionsThe involvement of PNs led to notable improvements in program outcomes. Expanding the peer navigator model within the BTC initiative is recommended to sustain and build upon these gains.

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来源期刊
CiteScore
2.60
自引率
7.10%
发文量
144
审稿时长
3-6 weeks
期刊介绍: The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).
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