Unusual, gigantic cystic echinococcosis in a woman living with HIV.

IF 1.4 4区 医学 Q4 IMMUNOLOGY
Khouloud Mnif, Amani Bouabdallah, Tarak Ben Jemaa, Emna Elleuch, Sami Fendri, Boussayma Hammami, Zeineb Mnif, Salah Boujelben, Chakib Marrakchi, Mounir Ben Jemaa
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Abstract

IntroductionCystic echinococcosis, or hydatidosis, is a parasite infection that can occur in humans. It can affect all organs, mostly the liver and the lungs. The number, size and evolution of those cysts is mediated by the immune system. Herein we report an unusual presentation of hydatidosis in an immunocompromised woman who lives with HIV.Case presentationOur patient was a 40-year-old female with a 2-decade history of HIV and echinococcal infection. She was in AIDS stage due to poor medical adherence. She presented a medullar toxicity to Albendazole, a medication she had been taking for years to control the echinococcal cysts, which were stable then. Upon stopping the Albendazole, she presented an enlargement of those cysts. Surgery was mandatory, and revealed five liver cysts, a 12cm-large kidney cyst, and a gigantic 20 cm-large retroperitoneal cyst. They were treated successfully, and the patient has been asymptomatic during the last 4 years since surgery, along with maintained HIV suppression.ConclusionHydatidosis can be negatively affected by immunosuppression such as HIV infection. However, the scarcity of the cases studying this association makes it difficult to fully grasp the possible interactions between those two diseases.

一名携带HIV病毒的妇女患有罕见的巨大囊性包虫病。
囊性包虫病,或称包虫病,是一种可发生在人类身上的寄生虫感染。它可以影响所有器官,主要是肝脏和肺部。这些囊肿的数量、大小和进化是由免疫系统调节的。在这里,我们报告一个不寻常的呈现包虫病在免疫功能低下的妇女谁生活与艾滋病毒。病例介绍:我们的患者是一名40岁的女性,有20年的HIV和棘球蚴感染史。由于治疗依从性差,她处于艾滋病阶段。她对阿苯达唑表现出髓质毒性,阿苯达唑是她多年来一直服用的一种药物,用于控制棘球蚴囊肿,当时病情稳定。停服阿苯达唑后,她的囊肿增大。手术是强制性的,结果发现5个肝囊肿,一个12厘米大的肾囊肿和一个巨大的20厘米大的腹膜后囊肿。他们得到了成功的治疗,患者在手术后的4年里一直无症状,并保持了HIV抑制。结论HIV感染等免疫抑制可对包虫病产生负面影响。然而,研究这种关联的病例的缺乏使得很难完全掌握这两种疾病之间可能的相互作用。
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来源期刊
CiteScore
2.60
自引率
7.10%
发文量
144
审稿时长
3-6 weeks
期刊介绍: The International Journal of STD & AIDS provides a clinically oriented forum for investigating and treating sexually transmissible infections, HIV and AIDS. Publishing original research and practical papers, the journal contains in-depth review articles, short papers, case reports, audit reports, CPD papers and a lively correspondence column. This journal is a member of the Committee on Publication Ethics (COPE).
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