{"title":"Asymptomatic viral shedding of mpox virus: What do we know?","authors":"Sara Almarzooqi","doi":"10.1177/09564624251332716","DOIUrl":"10.1177/09564624251332716","url":null,"abstract":"","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"597-598"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143763821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Georgina Morris, Lewis Haddow, Parameswaran N Sashidharan, Amber Savary-Trathen, Suneeta Soni, Charlotte Bigland, Hasan Mirza, Stephen L Walker
{"title":"British Association for Sexual Health and HIV National Guideline on the Management of Scabies in adults 2025.","authors":"Georgina Morris, Lewis Haddow, Parameswaran N Sashidharan, Amber Savary-Trathen, Suneeta Soni, Charlotte Bigland, Hasan Mirza, Stephen L Walker","doi":"10.1177/09564624251321264","DOIUrl":"10.1177/09564624251321264","url":null,"abstract":"<p><p>The British Association for Sexual Health and HIV UK guideline on the management of scabies has been updated in 2025. It provides details on the pathology and clinical features of scabies, with evidence-informed, practical recommendations on diagnosis, treatment and follow-up of adults and children aged 13 or above attending sexual health services. Key updates are detailed at the start of the article.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"516-532"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vivian I Avelino-Silva, Alexander Goncalvez, Whitney Engeran, Laura Boudreau, Michael Weinstein, Adele Schwartz Benzaken
{"title":"Expanding access to STI care with free of charge, convenient services in sexual health walk-in clinics.","authors":"Vivian I Avelino-Silva, Alexander Goncalvez, Whitney Engeran, Laura Boudreau, Michael Weinstein, Adele Schwartz Benzaken","doi":"10.1177/09564624251325310","DOIUrl":"10.1177/09564624251325310","url":null,"abstract":"<p><p><b>Background:</b> Sexually transmitted infections (STIs) are a long-standing public health issue with increasing incidence in recent years even though most STIs can be effectively treated or even cured with inexpensive medications.<b>Purpose/Design:</b> In this manuscript, we discuss factors that contribute with this concerning scenario, including modifications in the model of STI care in the United States; barriers for diagnosis and treatment; and scarcity of targeted STI prevention messages. We then describe the approach adopted by AIDS Healthcare Foundation to mitigate STI trends, with a focus on sexual health Wellness Centers.<b>Results:</b> The main characteristics of this program include free and convenient services with large volume capacity, sex-positive culture, advertisement of available resources, and accessibility to key populations at higher risk for STI acquisition.<b>Conclusions:</b> This experience could be adapted and expanded to other settings, supporting the public health mission of controlling the spread and detrimental outcomes of STIs.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"587-590"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085745/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jaiberth Antonio Cardona-Arias, Paula Andrea Álvarez Cossio, Angélica María Mancera Mieles, Laura Navales Balbín, Luis Felipe Higuita Gutiérrez
{"title":"Prevalence of HIV in sex workers attended in a health institution in Medellín, Colombia.","authors":"Jaiberth Antonio Cardona-Arias, Paula Andrea Álvarez Cossio, Angélica María Mancera Mieles, Laura Navales Balbín, Luis Felipe Higuita Gutiérrez","doi":"10.1177/09564624251330011","DOIUrl":"10.1177/09564624251330011","url":null,"abstract":"<p><p>BackgroundDespite being a key group for infection control, research on the prevalence of human immunodeficiency virus (HIV) among female sex sorkers (FSWs) in Colombia is scarce and outdated.MethodsThis is a prevalence study involving 739 FSWs who attended a healthcare provider in Medellín between 2019 and 2023. Data were collected from medical records to capture sociodemographic and health information. The prevalence of HIV was determined with its 95% confidence interval, and comparisons of HIV prevalence with sociodemographic and behavioral factors were conducted using Fisher's exact test and prevalence ratios. Analyses were performed using SPSS 29.0.ResultsMost FSWs had a primary education or less, and 50% were enrolled in the contributory health regime. Sixty-two percent reported using hallucinogens during sex, and 17% had relationships with individuals diagnosed with Sexually Transmitted Infections (STIs). The prevalence of HIV was 1.4%, with a higher prevalence among those with a previous STI diagnosis, at 12%. No significant differences were found based on other sociodemographic or behavioral variables.ConclusionThis study reveals a higher HIV prevalence compared to previous studies among FSWs, indicating the need for new health programs specifically tailored for this group, particularly for women with prior STIs, as they represent a key population for HIV infection that demands better healthcare approaches. Additionally, further research is needed to understand how sociodemographic changes impact infection dynamics in this population.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"577-582"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143752710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jane K Maganga, Kristen Riley, Crispin Mukerebe, Loyce Mhango, Donald Miyaye, Peter Shigella, Myung Hee Lee, Humphrey D Mazigo, Jennifer A Downs, John M Changalucha
{"title":"Validation of rapid point-of-care tests for herpes simplex virus-type 2 in rural Tanzania.","authors":"Jane K Maganga, Kristen Riley, Crispin Mukerebe, Loyce Mhango, Donald Miyaye, Peter Shigella, Myung Hee Lee, Humphrey D Mazigo, Jennifer A Downs, John M Changalucha","doi":"10.1177/09564624251327241","DOIUrl":"10.1177/09564624251327241","url":null,"abstract":"<p><p>BackgroundHerpes simplex virus-type 2 (HSV-2) affects nearly 500 million people worldwide. Up to 70% of women in Tanzania are infected by age 30. Point-of-care (POC) tests to detect HSV-2 antibodies are commercially available. We validated the performance of two HSV-2 POC tests in women in rural Tanzania.MethodsBlood from 56 women was tested for HSV-2 antibodies by Biogate Labs and OnSite Duo rapid tests and Kalon HSV-2 IgG ELISA. Results obtained from the POC tests were compared with those from the ELISA to determine sensitivity, specificity, positive and negative predictive values (PPV and NPV).ResultsThe Biogate had a sensitivity and specificity of 30.3% [15.6%-48.7%] and 100% [85.2%-100%], respectively. The OnSite Duo had a sensitivity and specificity of 69.7% [51.3%-84.4%] and 87.0% [66.4%-97.2%], respectively. The PPV and NPV for the Biogate was 100% [69.2%-100%] and 50% [44.4%-55.6%], respectively. The OnSite Duo had a PPV and NPV of 88.5% [72.3%-95.8%] and 66.7% [53.8%-77.5%], respectively.ConclusionThese tests had different performance characteristics, with the Biogate having a poor sensitivity and excellent specificity, and the OnSite Duo having a slightly better sensitivity though lower specificity. Validation of POC tests is important, as they can be valuable diagnostic tools in low-resource settings.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"563-567"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12124941/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143700482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Stephanie Melnychuk, Olga Balakireva, Daria Pavlova, Anna Lopatenko, Leigh M McClarty, Lisa Lazarus, Nicole Herpai, Michael Pickles, Sharmistha Mishra, Marissa L Becker, Paul Sandstrom, François Cholette
{"title":"Joint HIV and hepatitis C virus phylogenetic analyses signal network overlap among women engaged in sex work and men who purchase sex.","authors":"Stephanie Melnychuk, Olga Balakireva, Daria Pavlova, Anna Lopatenko, Leigh M McClarty, Lisa Lazarus, Nicole Herpai, Michael Pickles, Sharmistha Mishra, Marissa L Becker, Paul Sandstrom, François Cholette","doi":"10.1177/09564624241287259","DOIUrl":"10.1177/09564624241287259","url":null,"abstract":"<p><p>BackgroundTransmission of HIV and hepatitis C virus (HCV) are heavily influenced by complex interactions within sexual or injecting networks where risk behaviors occur. In Ukraine, women engaged in sex work (WSW) and men who purchase sex (MWPS) are disproportionately affected by both viruses. The aim of our study was to the investigate the influence of underlying networks on transmission of HIV and HCV.MethodsA cross-sectional integrated bio-behavioural survey was implemented among 560 WSW and 370 MWPS representative of sex work hotspots in Dnipro, Ukraine (December 2017 to March 2018). A portion of the HIV reverse transcriptase gene (<i>n</i> = 13; 62% WSW, 38% MWPS) and HCV NS5B gene (<i>n</i> = 46; 70% WSW, 30% MWPS) were sequenced from dried blood spot specimens. Tip-to-tip distances on phylogenetic trees were used to infer phylogenetic clusters for identifying potential transmission clusters.ResultsPhylogenetic analyses identified two HIV clusters containing four sequences (50% WSW; 50% MWPS) and 11 HCV clusters containing 31 sequences - the majority comprising infections in WSW (83.9%). Nearly half (45.4%) of HCV clusters contained at least one WSW with a history of injecting drugs.ConclusionsJoint analyses of HIV and HCV signal overlap in sex work and injecting networks in Ukraine, suggesting implications for the comprehensive coverage of prevention programs for WSW including harm reduction services. Conducting phylogenetic analyses with HCV may provide a more complete appraisal of underlying transmission networks than HIV alone, particularly in the context of high HIV treatment coverage yielding viral suppression.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"542-549"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12085746/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142346765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma B Monti, Danae Penichet, Monica Rudd, Deborah Yoong, Sara S Pathan, Asma Moin, Samantha A Myers, Darrell Hs Tan
{"title":"Hepatitis B prevention interventions during HIV post-exposure prophylaxis visits: A retrospective chart review.","authors":"Emma B Monti, Danae Penichet, Monica Rudd, Deborah Yoong, Sara S Pathan, Asma Moin, Samantha A Myers, Darrell Hs Tan","doi":"10.1177/09564624251325312","DOIUrl":"10.1177/09564624251325312","url":null,"abstract":"<p><p>BackgroundHepatitis B virus (HBV) disproportionately affects people at risk of HIV. Encounters for HIV post-exposure prophylaxis (PEP) create opportunities for HBV screening and prevention. We quantified HBV prevalence, susceptibility, and active/passive immunization use among patients seeking HIV PEP.MethodsWe conducted a retrospective chart review of patients requesting PEP at an academic hospital between 2001-2021 in Toronto, Canada. Patients were classified as HBV immune or susceptible based on laboratory tests. Among HBV-susceptible individuals, we quantified how often HBV vaccine and/or hepatitis B immune globulin (HBIG) were administered.ResultsWe identified 2018 PEP episodes, 75.3% being for sexual exposures. Mean age was 33.6 years. Among 1593 (78.9%) participants with available HBV testing data, six (0.4%) tested HBsAg-positive. Of 2018 episodes, 56.8% were among HBV-immune and 19.8% among HBV-susceptible participants; 23.1% were among participants of unknown status. Of susceptible participants, 55 (13.8%) received HBIG and 143 (35.8%) received HBV vaccinations.ConclusionsHBV prevalence was low but roughly one-fifth of patients seeking HIV PEP were HBV-susceptible. HBIG use was inconsistent with current guidelines, and a minority of HBV-susceptible individuals were vaccinated. More systematic HBV testing, increased HBV vaccination and more rational use of HBIG are needed in those seeking HIV PEP.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"550-557"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143605088","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Dorothy Frank, Mohanarathi Kawsar, Michael Eisenhut
{"title":"Effects of maternal antiretroviral drugs in pregnancy on haematological and biochemical parameters in neonates exposed in utero.","authors":"Dorothy Frank, Mohanarathi Kawsar, Michael Eisenhut","doi":"10.1177/09564624251326701","DOIUrl":"10.1177/09564624251326701","url":null,"abstract":"<p><p>BackgroundThe British HIV Association recommends the use of antiretroviral therapy (ART) in all pregnant women living with HIV to protect against mother to child transmission. ART may cause side effects including anaemia, macrocytosis and neutropenia.MethodsIn a retrospective study conducted in a District General Hospital in the United Kingdom in 2024 using a historical cohort, we compared neonatal haemoglobin, mean corpuscular volume (MCV), reticulocyte, neutrophil and lymphocyte counts, alanine aminotransferase and bilirubin levels on the first day of life and at 6 weeks of life in children born to mothers who at delivery were on azidothymidine (AZT) containing ART regimes with newborns not exposed to those regimes.ResultsOur study included 82 newborns exposed to maternal AZT-containing ART and 36 without exposure to an AZT-containing regimen. Newborns exposed to AZT had a mean (SD) haemoglobin of 15.5 (2.3) g/dl and a reticulocyte count of 216.8 (67.1) x10<sup>3</sup>/microliter, which were significantly lower compared to newborns not exposed with a haemoglobin of 17.6 (1.8) and a reticulocyte count of 273.1 (97.8) on the day of delivery. The MCV was with a mean (SD) of 117.2 (11.5) significantly higher in newborns exposed compared to those not exposed: 106.4 (17.1). There was no difference in other parameters at birth or in the above at 6 weeks of age.ConclusionsExposure to ART regimens containing AZT in pregnancy was associated with features of reduced fetal erythropoiesis in newborns.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"558-562"},"PeriodicalIF":1.4,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Helen Fifer, Muhammad Azam Ismail, Suneeta Soni, Uzochi Nwaosu, S Tariq Sadiq, Alice Milligan, John Saunders, Nicholas Medland
{"title":"British Association of Sexual Health and HIV UK National Guideline for the Management of infection with <i>Neisseria gonorrhoeae</i>, 2025.","authors":"Helen Fifer, Muhammad Azam Ismail, Suneeta Soni, Uzochi Nwaosu, S Tariq Sadiq, Alice Milligan, John Saunders, Nicholas Medland","doi":"10.1177/09564624251345195","DOIUrl":"10.1177/09564624251345195","url":null,"abstract":"<p><p>This guideline offers recommendations on the diagnosis, treatment and health promotion principles needed for the effective management of gonorrhoea. It is an update of the 2018 guideline.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251345195"},"PeriodicalIF":1.4,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144191814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}