International Journal of STD & AIDS最新文献_第5页

Association among therapeutic adherence, health literacy, and engagement in care: How to increase health-conscious management of HIV disease. 坚持治疗、健康知识普及和参与护理之间的关系：如何提高对艾滋病的健康管理意识。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-05 DOI: 10.1177/09564624241297838

Valentina Massaroni, Valentina Delle Donne, Pierluigi Francesco Salvo, Damiano Farinacci, Valentina Iannone, Gianmaria Baldin, Nicoletta Ciccarelli, Simona Di Giambenedetto

{"title":"Association among therapeutic adherence, health literacy, and engagement in care: How to increase health-conscious management of HIV disease.","authors":"Valentina Massaroni, Valentina Delle Donne, Pierluigi Francesco Salvo, Damiano Farinacci, Valentina Iannone, Gianmaria Baldin, Nicoletta Ciccarelli, Simona Di Giambenedetto","doi":"10.1177/09564624241297838","DOIUrl":"https://doi.org/10.1177/09564624241297838","url":null,"abstract":"Background: In the context of People Living with HIV (PLWH), poor health literacy (HL) seems to be linked to poorer health outcomes and reduced engagement in care. Additionally, the level of HL can affect HIV knowledge and may impact adherence to antiretroviral therapy (ART). This research explored the connection between ART adherence, HL, and engagement in care in a cohort of 250 PLWH receiving ART in Italy.Methods: A questionnaire was given to PLWH at Policlinico Gemelli in Rome to assess their health literacy and adherence to therapy. The Brief Health Literacy Screening (BHLS) and the Newest Vital Sign (NVS) were used to evaluate subjective and objective HL. Adherence levels were self-reported as poor, good, or excellent, and the assessment included the Patient Health Engagement Scale (PHE-S).Results: Notably, the majority of the sample comprised male individuals (67.9%), with 69.2% reporting a 10-years or longer duration between their HIV diagnosis and their initiation of ART. It was found that PLWH with poor adherence had low schooling, had been living with HIV for 1-5 years, were HCV co-infected, had a viremia >50 copies/mL, poor health status, poor engagement in care, and poor HL (p = <0.001). They exhibited lower mean scores on the subjective HL scale and lower CD4 T-cell counts and nadir CD4 T-cell counts (p < .001).Conclusion: Our study demonstrated a positive correlation between higher HL levels and improved disease management, treatment adherence, and overall physical and mental well-being. Enhanced HL capabilities are paramount in bolstering health management and treatment adherence.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624241297838"},"PeriodicalIF":1.4,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Improving sustainability in sexual health: A pilot project reintroducing reusable stainless steel vaginal specula at a sexual health clinic. 提高性健康的可持续性：在性健康诊所重新引入可重复使用不锈钢阴道窥器的试点项目。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-05 DOI: 10.1177/09564624241298873

Isobel Hall, Gillian Dean, Amanda Clarke

{"title":"Improving sustainability in sexual health: A pilot project reintroducing reusable stainless steel vaginal specula at a sexual health clinic.","authors":"Isobel Hall, Gillian Dean, Amanda Clarke","doi":"10.1177/09564624241298873","DOIUrl":"https://doi.org/10.1177/09564624241298873","url":null,"abstract":"Introduction: In line with the NHS net zero initiative, University Hospitals Sussex (UHS) committed to a Green Plan which included the introduction of reusable instruments. Following positive responses from a staff and patient survey in 2021, the sexual health and contraception (SHAC) department began a pilot scheme of 100 medium size reusable stainless steel vaginal specula (RMS) as an alternative to disposable acrylic models. The aim was to determine outcomes regarding sustainability goals and clinician experiences.Methods: Estimated carbon footprint and cost was calculated for actual use during study period, and expected use if RMS were to be exclusively used in the future. A staff questionnaire was distributed to ascertain attitudes towards RMS, including obstacles to their use and how these might be overcome.Results: Monthly medium size plastic specula use decreased during the pilot, resulting in a 22.4% reduction in carbon footprint. Exclusively using RMS for all examinations could reduce carbon emissions by 85.6%. Clinicians had an overall positive attitude towards RMS. Key obstacles to use were poorly stocked rooms and insufficient variety of size.Discussion: The success of this pilot scheme is being built upon by investing in a greater variety of sizes of RMS for use in SHAC aiming for a 100% reusable system.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624241298873"},"PeriodicalIF":1.4,"publicationDate":"2024-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Introducing simulation-based education to Genitourinary Medicine specialty training in the North West of England: A quality improvement project exploring trainee perspectives and impact. 在英格兰西北部的泌尿生殖医学专业培训中引入模拟教学：探索学员观点和影响的质量改进项目。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-09-03 DOI: 10.1177/09564624241280329

Izuchukwu Williams Ezeh

{"title":"Introducing simulation-based education to Genitourinary Medicine specialty training in the North West of England: A quality improvement project exploring trainee perspectives and impact.","authors":"Izuchukwu Williams Ezeh","doi":"10.1177/09564624241280329","DOIUrl":"10.1177/09564624241280329","url":null,"abstract":"Introduction: Simulation-based education (SBE) provides enactive experiences for learners. This project explores the utility of SBE in GUM training.Methods: Phase 1 was a qualitative survey of GUM trainees across the UK exploring their views on SBE. Phase 2 involved roll-out of SBE to new GUM trainees. Feedback was subsequently obtained.Results: Twenty-three participants were surveyed in phase 1. When asked to rate the relevance of SBE to curriculum competencies on a scale of 1 to 5 (1 = not relevant, 5 = highly relevant), the highest ratings (score ≥4) were for proctoscopy (4.1), IUD insertion (4.1), SDI removal (4.1), SDI insertion (4.0), and punch biopsy (4.0). All curriculum items scored ≥3. Eighty-three percent (n = 19) felt SBE will improve clinician confidence and competence. Following introduction of SBE, participants fed back on the relevance of the session. All 5 respondents rated the session ≥4 for addressing their clinical and curriculum goals. All respondents rated the session ≥4 for improving clinician confidence and competence. The session received an overall rating of 5, and respondents similarly rated 5 for more sessions.Conclusion: Trainees recognise the value of simulated learning experiences and its role in improving procedural competence and addressing bespoke human factor skills relevant to GUM.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1072-1074"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142125618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of STIs on cervical cancer screening: Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae in visual inspection with acetic acid (VIA) positive women in Mozambique. 性传播感染对宫颈癌筛查的影响：莫桑比克乙酸肉眼检查（VIA）阳性妇女的沙眼衣原体和淋病奈瑟菌感染率。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-08-27 DOI: 10.1177/09564624241272963

Alberto Sineque, Susanna Ceffa, Fernanda Parruque, Giovanni Guidotti, Cacilda Massango, Zita Sidumo, Carla Carrilho, Clara Bicho, Ricardina Rangeiro, Stefano Orlando, Cesaltina Lorenzoni, Fausto Ciccacci

{"title":"Impact of STIs on cervical cancer screening: Prevalence of Chlamydia trachomatis and Neisseria gonorrhoeae in visual inspection with acetic acid (VIA) positive women in Mozambique.","authors":"Alberto Sineque, Susanna Ceffa, Fernanda Parruque, Giovanni Guidotti, Cacilda Massango, Zita Sidumo, Carla Carrilho, Clara Bicho, Ricardina Rangeiro, Stefano Orlando, Cesaltina Lorenzoni, Fausto Ciccacci","doi":"10.1177/09564624241272963","DOIUrl":"10.1177/09564624241272963","url":null,"abstract":"Background: Cervical cancer, primarily from HPV, is prevalent in countries like Mozambique, with HIV individuals at higher risk. The Visual Inspection with Acetic Acid (VIA) screening method can be influenced by STIs like Chlamydia trachomatis (CT) and Neisseria gonorrhoeae (NG). This study examines CT and NG prevalence in HIV-positive and negative women using VIA in Mozambique's DREAM program.Methods: In this cross-sectional research conducted at a DREAM program facility in Maputo from 01/07/2021 to 31/05/2022, cervical specimens were taken from VIA-positive patients. CT/NG testing was performed using the Cobas® 4800 DNA CT/NG test. Statistical analyses focused on associations and prevalence rates, considering demographic, clinical, and exposure data.Results: Among 117 women, we observed a CT prevalence of 6.8% (8/117) and an NG prevalence of 2.6%(3/117). No significant associations between CT/NG infection rates and factors such as age, HIV status, VIA results, or high-risk HPV (hrHPV) was observed. We found a 47% prevalence of hrHPV infections among participants with cervical lesions; no significant association between hrHPV and CT/NG infections was observed.Conclusion: This study highlights the prevalence of CT and NG in VIA-positive women in Mozambique, emphasizing the STI burden and suggesting integration of STI screening in cervical cancer prevention strategies.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1019-1024"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080303","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Molluscum contagiosum is associated with atopic dermatitis and sexually transmitted infections in a matched case-control study using a national database. 在一项利用国家数据库进行的匹配病例对照研究中，传染性软疣与特应性皮炎和性传播感染有关。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-09-06 DOI: 10.1177/09564624241276571

Rachel C Hill, Aarushi K Parikh, Shari R Lipner

{"title":"Molluscum contagiosum is associated with atopic dermatitis and sexually transmitted infections in a matched case-control study using a national database.","authors":"Rachel C Hill, Aarushi K Parikh, Shari R Lipner","doi":"10.1177/09564624241276571","DOIUrl":"10.1177/09564624241276571","url":null,"abstract":"Background: Molluscum contagiosum (MC) is a poxvirus that manifests as firm, smooth, dome-shaped, umbilicated, flesh-colored papules. In adults, MC is commonly spread by sexual contact, and is self-limited in patients with intact immune systems but more widely distributed and difficult to treat in immunocompromised persons. We analyzed cases of adult MC for associations with immunosuppression, lifestyle risk factors, and sexually transmitted infections (STIs).Methods: Using the All of Us Research Program database, adults with MC were identified and matched with controls 1:10 based on demographic factors. Comorbidities, lifestyle risk factors, and medication exposures were analyzed. Odds ratios were calculated using logistic regression.Results: Our analysis included 146 cases of adults with MC and 1460 demographic-matched controls. Patients with MC were 48 years old on average, 59% female, and majority White (82.5%). Controls were similar for all demographic features. Adults with MC were more likely to have syphilis (odds ratio (OR) 16; 95% confidence interval (CI) 2.57-99.5), human immunodeficiency virus (HIV) (OR 9.54; 95% CI 3.95-23.0), chlamydia (OR 6.24; 95% CI 2.38-16.4), condyloma acuminata (OR 13.9; 95% CI 7.36-26.2), genital herpes (OR 4.13; 95% CI 1.87-9.15), or atopic dermatitis (AD) (OR 2.85; 95% CI 1.5-5.4) (all p < .01). There were no differences in prevalence of other comorbidities, lifestyle risk factors, nor medication exposures (all p > .05).Conclusions: We showed that adult MC is associated with AD and STIs, including HIV, chlamydia, condyloma acuminata, genital herpes, and syphilis. Sexually active adolescents and adults and those diagnosed with AD may be screened for MC and counseled on their potentially increased risk.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1050-1054"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142140091","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The tale of two Badakhshans: Determinants of access and utilization of HIV preventive services along the Afghan-Tajik border. 两个巴达赫尚人的故事：阿富汗-塔吉克边境地区获得和利用艾滋病毒预防服务的决定因素。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-08-28 DOI: 10.1177/09564624241276904

Harsimren Sidhu, Frezghi Gebreweldi, Alissa Davis, Jonbek Jonbekov, Mahbat Bahramov, Anindita Dasgupta, Tara McCrimmon, Phillip Marotta, Kianoush Dehghani

{"title":"The tale of two Badakhshans: Determinants of access and utilization of HIV preventive services along the Afghan-Tajik border.","authors":"Harsimren Sidhu, Frezghi Gebreweldi, Alissa Davis, Jonbek Jonbekov, Mahbat Bahramov, Anindita Dasgupta, Tara McCrimmon, Phillip Marotta, Kianoush Dehghani","doi":"10.1177/09564624241276904","DOIUrl":"10.1177/09564624241276904","url":null,"abstract":"Background: Injection of opioids has contributed to growing HIV epidemics in Tajikistan and Afghanistan. This qualitative study explored determinants of access to primary prevention and screening for HIV among people who inject drugs (PWID) residing in border communities of Gorno-Badakhshan, Tajikistan and Badakhshan, Afghanistan.Methods: Semi-structured interviews were conducted with PWID, community leaders, and healthcare workers. The social-ecological model was used to inform a thematic analysis of determinants of access.Results: There were no preventive or screening services for HIV in the border districts of Afghanistan. Barriers to accessing HIV-related services in Tajikistan, and to accessing general health services in Afghanistan, included: lack of knowledge about HIV, inaccessible communities with poor infrastructure, discrimination and violence against women, and stigmatization of PWID and people living with HIV. Access to HIV-related and other health services by PWID was facilitated by community leader support, family support, outreach services, and linkage of harm reduction services with HIV testing and care.Conclusion: Urgent interventions are needed to stem the escalating HIV epidemic in Afghanistan and enhance existing services in Tajik border communities. This qualitative study offers insights into barriers and facilitators for accessing HIV prevention and screening services among PWID, suggesting potential interventions.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1025-1031"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11488286/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful combination therapy of trichloroacetic acid, podophyllin, and electrocautery on giant condylomata acuminata. 三氯乙酸、荚叶素和电灼联合疗法成功治疗巨型尖锐湿疣。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-08-28 DOI: 10.1177/09564624241276574

Hasbiallah Yusuf, Muhammad Izazi Hari Purwoko

{"title":"Successful combination therapy of trichloroacetic acid, podophyllin, and electrocautery on giant condylomata acuminata.","authors":"Hasbiallah Yusuf, Muhammad Izazi Hari Purwoko","doi":"10.1177/09564624241276574","DOIUrl":"10.1177/09564624241276574","url":null,"abstract":"Introduction: Giant condylomata acuminata (GCA) is a rare presentation of anogenital wart (AGW), invasive locally but does not metastasize. Combination therapy for GCA is suggested based on modalities and experiences. The combination of TCA and podophyllin has showed good efficacy, followed by electrocautery to eradicate warts. Case: A 24-year-old male had a chief complaint of large warts on the base of the penis that had started to bleed for 4 weeks. The initial lesion appeared 8 months prior as a small varucose papule. The patient is unmarried and has history of sexual contact with sex workers. Physical examination showed multiple verrucous papules, flesh-coloured, cauliflower-like shaped, 5 × 2 × 1 cm in size. The patient tested negative for HIV infection. Histopathological examination showed acanthosis, exophytic growth, parakeratosis, and koilocytosis with no signs of malignancy. This patient received a combination of TCA 90% and podophyllin 25% to initially reduce the tumor size, followed by electrocautery to eradicate the remaining lesions. The tumor showed complete clearance. Discussion: There is no definitive evidence that one therapy is superior to completely eliminating warts. Combination therapy of TCA and podophyllin leads to complete wart clearance, followed by electrocautery to destroy smaller warts.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1079-1083"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142080304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hepatitis A vaccination in a racially and sexually diverse population of gay, bisexual, and other men who have sex with men: Findings from the QVax study. 在男同性恋、双性恋和其他男男性行为者等不同种族和性取向人群中接种甲型肝炎疫苗：QVax 研究结果。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-09-02 DOI: 10.1177/09564624241278765

Tiffany Y Guo, Perry N Halkitis, Kendra Lewis, Kristen D Krause

{"title":"Hepatitis A vaccination in a racially and sexually diverse population of gay, bisexual, and other men who have sex with men: Findings from the QVax study.","authors":"Tiffany Y Guo, Perry N Halkitis, Kendra Lewis, Kristen D Krause","doi":"10.1177/09564624241278765","DOIUrl":"10.1177/09564624241278765","url":null,"abstract":"Background: Previous studies found vaccination uptake of vaccine-preventable diseases (VPD) to be associated with race/ethnicity and medical mistrust among key populations, however, few studies examine Hepatitis A vaccination uptake.Methods: This cross-sectional study used online survey data collected from NJ and NY residents identifying as lesbian, gay, bisexual, transgender, queer (LGBTQ+) from October 2021 through November 2022.Results: This study used a subsample of 222 gay, bisexual, and other cisgender men, 66.7% White, with mean age 41.22 years (SD = 15.23), and 60% fully vaccinated for Hepatitis A. Overall, average group-based medical mistrust scores did not differ among non-vaccinated participants compared to fully or partially vaccinated participants. However, higher group-based medical mistrust scores were associated with non-White identifying participants, and were highest among Hispanic/Latinx (2.68, sd = 0.43) and Black non-Hispanic (2.58, sd = 0.50) participants (p < .001). Vaccination patterns did not differ among fear or vaccine confidence-based items.Conclusions: Our results contribute to the limited knowledge of differences in Hepatitis A vaccination uptake among men who have sex with men, and support the need for targeted intervention programs that acknowledge the diverse population of LGBTQ + identifying individuals and their associated health behaviors.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1032-1041"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119799","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effective management of multidrug-resistant HIV with lenacapavir and fostemsavir: A case study. 来那卡韦和福斯替沙韦对耐多药艾滋病病毒的有效管理：案例研究。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 DOI: 10.1177/09564624241296583

Francisca Bartilotti Matos, Dara Mbanze, Perpétua Gomes, Cristóvão Figueiredo, Daniel Coutinho, Sofia Nunes, Carlos Azevedo, Joana Fragoso, Tiago Teixeira, Luís Malheiro

引用次数: 0

Cervical precancer and invasive cancer among women living with HIV in Latin America: A systematic review and meta-analysis. 拉丁美洲感染艾滋病毒妇女的宫颈癌前病变和浸润性癌症：系统回顾和荟萃分析。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2024-11-01 Epub Date: 2024-09-02 DOI: 10.1177/09564624241276577

Ginna Fernández-Deaza, Gabriela Negrete-Tobar, María Caicedo, Nicolás Téllez, Maeve B Mello, Massimo Ghidinelli, Bernardo Nuche-Berenguer, Raúl Murillo

{"title":"Cervical precancer and invasive cancer among women living with HIV in Latin America: A systematic review and meta-analysis.","authors":"Ginna Fernández-Deaza, Gabriela Negrete-Tobar, María Caicedo, Nicolás Téllez, Maeve B Mello, Massimo Ghidinelli, Bernardo Nuche-Berenguer, Raúl Murillo","doi":"10.1177/09564624241276577","DOIUrl":"10.1177/09564624241276577","url":null,"abstract":"Background: Data on the occurrence of cervical precancer and cancer among women living with HIV (WLHIV) in Latin American countries (LAC) are scarce and highly heterogeneous.Methods: We conducted a systematic review summarizing data about the incidence/prevalence of invasive cervical cancer (CC) and high-grade precancerous lesions among WLHIV in LAC. Literature in PubMed and LILACS was searched. The primary outcome was invasive cancer incidence, and prevalence of high-grade lesions as key indicators for the WHO CC elimination strategy. Individual reports on invasive cancer incidence and prevalence of precancerous lesions were obtained, and a random effects meta-analysis was conducted for the latter.Results: In total, 34,343 WLHIV from four studies reporting CC incidence in seven LAC were included, and 6079 WLHIV from 17 studies reporting prevalence of precancerous lesions in three LAC were included. CC incidence ranged between 136.0 and 398.4 per 100,000 WLHIV (with or without antiretroviral therapy). The weighted prevalence of high-grade lesions was 4.1% (95%CI: 3.8%-6.0%) with a double peak at ages 20-24 and 35-39 years. Differences in prevalence of high-grade lesions were also observed by screening approach: co-testing (11.9%), colposcopy (6.0%), cytology (4.2%), and HPV tests (3.2%).Conclusions: The high incidence of invasive cancer and prevalence of high-grade lesions underline challenges to reach the WHO's elimination goal of CC incidence below four per 100,000 among WLHIV. Moreover, the high prevalence of high-grade lesions at younger ages than in the general population is a call to accelerate the implementation of the new WHO screening recommendations in WLHIV.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"1008-1018"},"PeriodicalIF":1.4,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142119798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0