International Journal of STD & AIDS最新文献

{"title":"Ten cases of erythematous-petechial lesions of the palate caused by fellatio, and a review of the literature.","authors":"Stefano Veraldi, Stefano Ramoni, Italo Francesco Aromolo, Gianluca Nazzaro","doi":"10.1177/09564624251347474","DOIUrl":"https://doi.org/10.1177/09564624251347474","url":null,"abstract":"<p><p>Erythematous-petechial lesions of the palate caused by fellatio are probably frequent. However, they have rarely been reported in the literature because they are not easily visible by the patient, are almost always asymptomatic and heal spontaneously within a few days. We report 10 patients (9 females and 1 male, with an age ranging from 29 to 59 years) with this condition. Two patients complained of mild burning sensation in the oral cavity. In all patients it was possible to exclude sexually transmitted infections. No treatment was prescribed. Complete remission was observed within 2 weeks.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251347474"},"PeriodicalIF":1.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexually transmitted infections and bacterial vaginosis and preterm birth in pregnant people living with HIV: A population-based cohort study.","authors":"Jeffrey Man Hay Wong, Gal Av-Gay, Terry Lee, Arezou Azampanah, Chelsea Elwood, Julie van Schalkwyk, Laura Sauvé, Deborah Money","doi":"10.1177/09564624251347458","DOIUrl":"https://doi.org/10.1177/09564624251347458","url":null,"abstract":"<p><p>BackgroundWhile individual sexually transmitted infections are linked with preterm births, their synergistic impact among pregnant people living with HIV (PLWH) remain unclear. We aimed to identify the impact of antenatal sexually transmitted infections and bacterial vaginosis on preterm birth in PLWH.MethodsWe completed a population-based cohort study using the British Columbia Perinatal HIV Surveillance Database, capturing all births in PLWH from January 1997 to December 2022. Univariate risk factors for preterm birth were identified using chi-squared tests, Fisher's exact tests and t-tests, followed by a multivariate logistic regression analysis.ResultsOf 578 singleton pregnancies, 111 (19.2%) had preterm births, of which 34 (31%) delivered before 34 weeks gestational age. In our population, 11% were identified with a sexually transmitted infection or bacterial vaginosis (STIBV) in pregnancy. The preterm birth rate in PLWH with antenatal STIBV was 37% compared to 17% in PLWH without STIBV (OR: 2.18; 95% CI (1.50 - 3.16); <i>p</i> = .0003). Preterm deliveries were more common in individuals with concurrent Hepatitis C (OR: 2.42; <i>p</i> < .0001), antenatal diagnosis of <i>Chlamydia</i> <i>trachomatis</i> (OR 2.17; <i>p</i> = .036), <i>Trichomonas</i> <i>vaginalis</i> (OR: 2.78; <i>p</i> < .001) and bacterial vaginosis (OR: 2.15; <i>p</i> = .003). After adjusting for ethnicity, history of preterm birth, substance use, concurrent Hepatitis C, CD4 count and viral suppression at delivery, STIBV remains an independent risk factor (OR: 2.09; 95% CI: 1.04 - 4.19; <i>p</i> = .039).ConclusionAmong PLWH, antenatal screening for sexually transmitted infections and bacterial vaginosis can identify individuals at the highest risk of preterm birth.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251347458"},"PeriodicalIF":1.4,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144186988","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"HIV in Syria: An urgent call for action amid a collapsed health system and widespread stigma.","authors":"Abdulkader Mohammad, Abdulmalek Aljafari, Ahmad Mohammad Al Zamel","doi":"10.1177/09564624251347418","DOIUrl":"https://doi.org/10.1177/09564624251347418","url":null,"abstract":"","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251347418"},"PeriodicalIF":1.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The influence of socioeconomic factors and apolipoprotein ε genotype on cognitive outcomes in a multi-ethnic sample living with HCV and HIV.","authors":"Shanna L Burke, Adrienne Grudzien, Tan Li, Stephanie Garcia, Sabrina Sales Martinez, Emily Jurich, Daniel R Jimenez, Jacqueline Hernández, Qingyun Liu, Tahirah A Tyrell, Natalie Goulett, Adriana L Campa, Zoran Bursac, Marianna K Baum","doi":"10.1177/09564624251324968","DOIUrl":"https://doi.org/10.1177/09564624251324968","url":null,"abstract":"<p><p>BackgroundThis study examined associations between apolipoprotein (APOE) ε4 carrier status and Mini-Mental State Examination (MMSE) scores and whether this relationship varied among adults living with HIV/HCV, HIV, HCV, or neither. We also examined whether sociodemographic factors moderated associations between APOE ε4 carrier status and MMSE scores.MethodsA secondary analysis of cognitive, psychological, and sociodemographic data from the Miami Adult Studies on HIV (MASH) cohort (<i>n</i> = 493) was completed. Banked blood samples underwent APOE genotyping. Bivariate analyses examined potential differences across participants by HIV and/or HCV statuses and by APOE ε4 carrier status. Multiple linear regression was conducted to test the adjusted moderation effect of each sociodemographic variable between APOE ε4 carrier status and MMSE scores within each group.ResultsSociodemographic factors, such as income, education, food insecurity, and employment influenced associations between APOE ε4 carrier status and MMSE scores among participants with HIV/HCV. Participants with APOE ε4 genotypes living with HCV had higher MMSE scores than non-APOE ε4 carriers.ConclusionThese results reinforce the need for future studies examining (1) the impact of APOE genotype on cognitive functioning while considering socioeconomic factors and (2) the influence of socioeconomic factors on cognitive scores among individuals living with HIV and or HCV.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251324968"},"PeriodicalIF":1.4,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144173405","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Call to action: A roadmap for HIV prevention and PrEP adoption in the Gulf region.","authors":"Ahmed A AlHammadi, Ahmad Alharbi, Ahmad Subhi, Ali Al Saeed, Batool Ali, Jehad Abdalla, Roaa Sultan Alosaimi, Sara Osman","doi":"10.1177/09564624251346055","DOIUrl":"https://doi.org/10.1177/09564624251346055","url":null,"abstract":"<p><p><b>Background</b>: Pre-exposure prophylaxis (PrEP) is a highly effective biomedical intervention for preventing HIV transmission. However, despite its proven efficacy, PrEP uptake in the Gulf Cooperation Council (GCC) countries remains suboptimal due to multiple systemic, legal, and sociocultural challenges.<b>Purpose</b>: This expert opinion review aims to present a strategic roadmap to enhance HIV prevention and support the integration and scale-up of PrEP adoption across the GCC region.<b>Research Design</b>: This narrative review synthesises insights from regional and international literature, expert panel discussions, and public health frameworks to develop practical recommendations for improving PrEP implementation in GCC countries.<b>Study Sample</b>: The review draws upon the perspectives of infectious disease specialists, public health policymakers, and HIV prevention advocates with expertise in the GCC region, alongside selected peer-reviewed and grey literature addressing HIV and PrEP in similar sociopolitical contexts.<b>Data Collection and/or Analysis</b>: Qualitative synthesis of the existing barriers and facilitators of PrEP adoption was conducted. The authors applied a framework-based approach to identify core pillars for effective policy, clinical, and public health interventions relevant to the GCC context.<b>Results</b>: Four strategic pillars were identified: (1) establishing a legal and regulatory framework with national PrEP guidelines; (2) improving risk identification and expanding access for individuals at heightened HIV risk; (3) enhancing healthcare provider education and capacity-building; and (4) conducting culturally sensitive public awareness campaigns. Financial accessibility and patient-provider communication were also highlighted as key to improving adherence and uptake.<b>Conclusions</b>: A coordinated, multi-sectoral approach is essential for advancing PrEP integration into national HIV prevention efforts across the GCC. By addressing structural and societal barriers, this roadmap provides actionable guidance to reduce new HIV infections and promote equitable access to PrEP for at-risk populations.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251346055"},"PeriodicalIF":1.4,"publicationDate":"2025-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Symmetrical drug-related intertriginous flexural exanthema following syphilis treatment with benzathine benzylpenicillin.","authors":"Darshanie Nayanakanthi Mallikarachchi, Amy Bennett, Bogusia Kasternow","doi":"10.1177/09564624251347110","DOIUrl":"https://doi.org/10.1177/09564624251347110","url":null,"abstract":"<p><p>Symmetrical drug-related intertriginous flexural exanthema (SDRIFE), formerly known as 'Baboon Syndrome', is a rare benign allergic reaction, often triggered by systemic drugs. This case report presents a 37-year-old woman with syphilis who developed SDRIFE following benzathine benzylpenicillin treatment. This is the first published case of SDRIFE during syphilis treatment and emphasizes the importance of early recognition and specialist input to ensure safe and effective treatment continuation.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251347110"},"PeriodicalIF":1.4,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144150474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visceral and cutaneous leishmaniasis in a person living with HIV.","authors":"Nicolas Laverde-Sudupe, Angela Lizeth Giraldo-Serna, Mariana Vasquez-Amaya, Fabián Carrera-Patiño","doi":"10.1177/09564624251346029","DOIUrl":"https://doi.org/10.1177/09564624251346029","url":null,"abstract":"<p><p>Leishmaniasis, the third most common parasitic infection in persons living with HIV, typically presents in cutaneous, mucocutaneous, or visceral forms. This case report describes a 24-year-old male with advanced HIV/AIDS (CD4+ count 3 cells/mm³) who presented with neurological deterioration due to cerebral toxoplasmosis. During hospitalization, he developed atypical genital ulcers and persistent pancytopenia. Bone marrow examination revealed amastigotes consistent with <i>Leishmania</i> spp., indicating concurrent visceral and mucocutaneous leishmaniasis. Treatment with liposomal amphotericin B followed by miltefosine resulted in clinical improvement of the genital ulcers. This case highlights the atypical presentation of leishmaniasis in a patient living with HIV, deviating from classic descriptions and underscoring the diagnostic challenges. The presence of <i>Leishmania</i> amastigotes in the bone marrow, coupled with unusual cutaneous manifestations, emphasizes the need for a high index of suspicion for opportunistic infections in patients living with HIV/AIDS with unexplained findings, even without a history of travel to endemic areas. Timely diagnosis through bone marrow examination and appropriate multi-drug therapy are crucial for managing such complex co-infections.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251346029"},"PeriodicalIF":1.4,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of <i>Chlamydia trachomatis</i> and associated factors in pregnant adolescent and young adult females from Morelos, Mexico: A cross-sectional study.","authors":"Julio C Muñiz-Salgado, Regina B Hurtado-Arroyo, Santa García-Cisneros, María Olamendi-Portugal, Miguel Angel Sánchez-Aleman, Dayana Nicté Vergara-Ortega, Antonia Herrera-Ortiz","doi":"10.1177/09564624251344436","DOIUrl":"https://doi.org/10.1177/09564624251344436","url":null,"abstract":"<p><p>Background<i>Chlamydia trachomati</i>s (<i>Ct</i>) is considered the most common bacterial sexually transmitted infection worldwide, adolescent and young adult female are at high risk of contracting this infection. The aim of this study was to evaluate the prevalence of <i>Ct</i> and associated factors in pregnant adolescents and young adults (PAYA).MethodsThis cross-sectional study was conducted between 2018 and 2020 with Mexican PAYA famales aged 12-24 years, who attended health services for pregnancy care. <i>Ct</i> was detected by PCR of the <i>omp1</i> gene. The prevalence of <i>Ct</i> was reported with a 95% confidence interval. Factors associated with <i>Ct</i> prevalence were identified by multivariate logistic regression analysis.ResultsThe prevalence of <i>Ct</i> was 12.9% (95% CI: 9-15) and 18.5% of them had coinfection with HSV-2 (aOR 3.1; 95% CI: 1.49-6.42). Frequent alcohol consumption (aOR 2.3, 95% CI:1.07-5.08), antibiotic use in the last year (aOR 1.9, 95% CI:1.06-3.39), ≥3 lifetime sexual partners (aOR 0.5, 95% CI:0.24-0.98) and hormonal contraceptive use (aOR 2.2, 95% CI:1.08-4.34) were associated with <i>Ct</i>.ConclusionThe prevalence of <i>Ct</i> in PAYA is high. Screening should be performed in symptomatic and asymptomatic pregnant females to reduce the risk of vertical transmission and the risk of pelvic inflammatory disease and infertility.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251344436"},"PeriodicalIF":1.4,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Disseminated cutaneous leishmaniasis in a person living with HIV.","authors":"Meryem Soughi, Samira Rabhi, Mouna Guechchati, Zakia Douhi, Sara Elloudi, Hanane Baybay, Fatima Zahra Mernissi","doi":"10.1177/09564624251344435","DOIUrl":"https://doi.org/10.1177/09564624251344435","url":null,"abstract":"<p><p>Leishmaniasis is a tropical disease caused by protozoa belonging to the group of <i>Leishmania</i> species. Visceral leishmaniasis, diffuse cutaneous leishmaniasis, and atypical forms of cutaneous leishmaniasis are common in acquiring HIV. We report a case of atypical cutaneous leishmaniasis (CL) in a person living with HIV.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"9564624251344435"},"PeriodicalIF":1.4,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144132392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Shingles in HIV: Outcome and discovery.","authors":"Mouna Guechchati, Meryem Soughi, Samira Rabhi, Hamza Idrissi Janati, Zakia Douhi, Sara Elloudi, Hanane Baybay, Fatima Zahra Mernissi","doi":"10.1177/09564624251324975","DOIUrl":"10.1177/09564624251324975","url":null,"abstract":"<p><p><b>Background:</b> Herpes zoster (HZ) is a frequent manifestation in people living with HIV (PLHIV), with a significantly higher incidence compared to the general population. It often presents as an early indicator of immunosuppression, making timely diagnosis and treatment crucial. <b>Methods:</b> This retrospective study, conducted from January 2015 to September 2024, analyzed 45 PLHIV diagnosed with HZ. Patients were recruited from the Infectious Diseases Department (for HIV-related HZ cases) and the Dermatology Department (for complicated HZ cases requiring hospitalization). Clinical and demographic data were collected, including ART status, HZ presentation, and treatment outcomes. <b>Results:</b> The mean patient age was 36.35 years, with a male predominance (M/F ratio: 8). Among the cohort, 12 patients had undiagnosed HIV, and HZ was the presenting symptom that led to HIV diagnosis. The thoracic metameric variant was the most common, with erythematous-vesicular, necrotic-hemorrhagic, and bullous forms observed. 21 patients were on antiretroviral therapy (ART), six of whom developed HZ shortly after ART initiation. Treatment involved oral or intravenous acyclovir, with hospitalization required for complicated or multi-metameric forms and high-risk patients. Outpatient management with close monitoring was provided for stable cases. <b>Conclusions:</b> HZ remains a significant opportunistic infection in PLHIV, often serving as a sentinel sign of undiagnosed HIV. Early HIV screening in patients presenting with HZ and timely initiation of antiviral therapy are essential for improved outcomes. Enhanced awareness and integrated HIV-HZ management strategies are crucial in clinical practice.</p>","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"506-509"},"PeriodicalIF":1.4,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143531276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}