International Journal of STD & AIDS最新文献_第7页

An uncommon cause of persistent infection by Trichomonas vaginalis. 阴道毛滴虫持续感染的一个不常见原因。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-09-26 DOI: 10.1177/09564624241260756

Jimena Varona, María Jesús Barberá, Josefina López de Munain

引用次数: 0

Successful outcome of performing CO2 laser ablation in a middle-aged female with angiokeratoma of Fordyce. 为一名患有福特斯血管角化瘤的中年女性成功实施二氧化碳激光消融术。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-11-09 DOI: 10.1177/09564624241299571

Janice Reema Lewis, Ramesha Bhat M, Archana Bhat, Michelle Serene Fernandes, Jacintha Martis

引用次数: 0

Mycobacterium avium complex (MAC) infection in severely immunocompromised people living with HIV: Findings from a five-year cohort. 免疫力严重低下的艾滋病病毒感染者中的复合分枝杆菌（MAC）感染：一项为期五年的队列研究结果。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-11-05 DOI: 10.1177/09564624241297835

María Del Rocío Fernández-Díaz, Naya Faro-Miguez, María Aguilera-Franco, Leopoldo Muñoz-Medina, Andrés Ruiz-Sancho, Javier Rodríguez-Granger, Emilio Guirao-Arrabal

{"title":"Mycobacterium avium complex (MAC) infection in severely immunocompromised people living with HIV: Findings from a five-year cohort.","authors":"María Del Rocío Fernández-Díaz, Naya Faro-Miguez, María Aguilera-Franco, Leopoldo Muñoz-Medina, Andrés Ruiz-Sancho, Javier Rodríguez-Granger, Emilio Guirao-Arrabal","doi":"10.1177/09564624241297835","DOIUrl":"10.1177/09564624241297835","url":null,"abstract":"Background: We sought to clarify the current incidence, risk factors and symptoms of disseminated Mycobacterium avium complex (dMAC) infection in admitted people living with HIV in a hospital in the Southeast of Spain.Methods: 5-years observational, retrospective and single-centre study. Demographic, clinical and analytical variables, along with microbiological, treatment and follow-up were collected.Results: Five cases of dMAC infection in severely immunocompromised people living with HIV people living were found. dMAC was diagnosed in 22.7% of patients under 100 CD4. All patients presented with fever and clinical manifestations of pneumonia, lymphadenopathy, or gastrointestinal symptoms. Despite low CD4 levels and high viral loads in some cases, primary prophylaxis had not been previously administered.Conclusions: Until 2018, U.S. American guidelines recommended antimycobacterial prophylaxis for patients with low CD4 cell counts, a practice not adopted in Europe. Untreated dMAC infection is associated with high morbidity and mortality rates. dMAC infection represents a prevalent disease in severely immunosuppressed people living with HIV. dMAC requires a high index of suspicion in this population, in order to perform mycobacterial cultures from different samples.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"126-131"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583117","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association among therapeutic adherence, health literacy, and engagement in care: How to increase health-conscious management of HIV disease. 坚持治疗、健康知识普及和参与护理之间的关系：如何提高对艾滋病的健康管理意识。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-11-05 DOI: 10.1177/09564624241297838

Valentina Massaroni, Valentina Delle Donne, Pierluigi Francesco Salvo, Damiano Farinacci, Valentina Iannone, Gianmaria Baldin, Nicoletta Ciccarelli, Simona Di Giambenedetto

{"title":"Association among therapeutic adherence, health literacy, and engagement in care: How to increase health-conscious management of HIV disease.","authors":"Valentina Massaroni, Valentina Delle Donne, Pierluigi Francesco Salvo, Damiano Farinacci, Valentina Iannone, Gianmaria Baldin, Nicoletta Ciccarelli, Simona Di Giambenedetto","doi":"10.1177/09564624241297838","DOIUrl":"10.1177/09564624241297838","url":null,"abstract":"Background: In the context of People Living with HIV (PLWH), poor health literacy (HL) seems to be linked to poorer health outcomes and reduced engagement in care. Additionally, the level of HL can affect HIV knowledge and may impact adherence to antiretroviral therapy (ART). This research explored the connection between ART adherence, HL, and engagement in care in a cohort of 250 PLWH receiving ART in Italy.Methods: A questionnaire was given to PLWH at Policlinico Gemelli in Rome to assess their health literacy and adherence to therapy. The Brief Health Literacy Screening (BHLS) and the Newest Vital Sign (NVS) were used to evaluate subjective and objective HL. Adherence levels were self-reported as poor, good, or excellent, and the assessment included the Patient Health Engagement Scale (PHE-S).Results: Notably, the majority of the sample comprised male individuals (67.9%), with 69.2% reporting a 10-years or longer duration between their HIV diagnosis and their initiation of ART. It was found that PLWH with poor adherence had low schooling, had been living with HIV for 1-5 years, were HCV co-infected, had a viremia >50 copies/mL, poor health status, poor engagement in care, and poor HL (p = <0.001). They exhibited lower mean scores on the subjective HL scale and lower CD4 T-cell counts and nadir CD4 T-cell counts (p < .001).Conclusion: Our study demonstrated a positive correlation between higher HL levels and improved disease management, treatment adherence, and overall physical and mental well-being. Enhanced HL capabilities are paramount in bolstering health management and treatment adherence.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"132-140"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583123","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Case series of two persons living with HIV with detectable viral loads initiated then suppressed on cabotegravir/rilpivirine with lenacapavir. 两名检测到病毒载量的艾滋病病毒感染者的病例系列，他们开始使用卡博特拉韦/利匹韦林联合来那卡韦治疗，随后病情得到抑制。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241288293

Kimberly L O'Neil, Patrick R Ching, Robert T Higginson, Patricia Pecora Fulco

{"title":"Case series of two persons living with HIV with detectable viral loads initiated then suppressed on cabotegravir/rilpivirine with lenacapavir.","authors":"Kimberly L O'Neil, Patrick R Ching, Robert T Higginson, Patricia Pecora Fulco","doi":"10.1177/09564624241288293","DOIUrl":"10.1177/09564624241288293","url":null,"abstract":"Long-acting (LA) cabotegravir/rilpivirine (CAB/RPV) is primarily prescribed for virologically suppressed persons living with HIV (PLWH). Patients experiencing pill dysphagia or profound adherence challenges were excluded from the phase 3 studies, but recent reports demonstrate successful treatment in PWLH with baseline viremia. We describe two PLWH with detectable viral loads (VL) with multidrug resistance mutations. They were unable to sustain virologic suppression on oral therapy with historical poor adherence and dysphagia. Initiation of intramuscular CAB/RPV with subcutaneous lenacapavir (LEN) injections was necessary with baseline resistance. Due to anorexia and a low muscle mass, one patient received CAB/RPV injections in the vastus lateralis rather than the gluteal muscle with a 67-day delay between injections three and four due to health challenges. Both achieved viral suppression on monthly CAB/RPV with LEN. A return to health with a BMI increase from <14 kg/m2 to almost 17 kg/m2 resulted in the second patient. Injectable LA ART (CAB/RPV + LEN) in PLWH with detectable viremia results in sustained virologic suppression and a return to health and should now be considered a novel option for MDR patients with an inability to adhere to oral regimens.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"155-157"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371836","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

British Association of Sexual Health and HIV UK national guideline for the management of anogenital herpes, 2024. 英国性健康和艾滋病协会《2024 年英国肛门疱疹管理国家指南》。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-10-07 DOI: 10.1177/09564624241282396

Raj Patel, John Green, Benjamin Moran, Emily Clarke, Kanchana Seneviratne, Ceri Evans, Felicity Young, Marian Nicholson, Emanuela Pelosi, Margaret Kingston, Elizabeth Foley

引用次数: 0

Improving sustainability in sexual health: A pilot project reintroducing reusable stainless steel vaginal specula at a sexual health clinic. 提高性健康的可持续性：在性健康诊所重新引入可重复使用不锈钢阴道窥器的试点项目。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-11-05 DOI: 10.1177/09564624241298873

Isobel Hall, Gillian Dean, Amanda Clarke

{"title":"Improving sustainability in sexual health: A pilot project reintroducing reusable stainless steel vaginal specula at a sexual health clinic.","authors":"Isobel Hall, Gillian Dean, Amanda Clarke","doi":"10.1177/09564624241298873","DOIUrl":"10.1177/09564624241298873","url":null,"abstract":"Introduction: In line with the NHS net zero initiative, University Hospitals Sussex (UHS) committed to a Green Plan which included the introduction of reusable instruments. Following positive responses from a staff and patient survey in 2021, the sexual health and contraception (SHAC) department began a pilot scheme of 100 medium size reusable stainless steel vaginal specula (RMS) as an alternative to disposable acrylic models. The aim was to determine outcomes regarding sustainability goals and clinician experiences.Methods: Estimated carbon footprint and cost was calculated for actual use during study period, and expected use if RMS were to be exclusively used in the future. A staff questionnaire was distributed to ascertain attitudes towards RMS, including obstacles to their use and how these might be overcome.Results: Monthly medium size plastic specula use decreased during the pilot, resulting in a 22.4% reduction in carbon footprint. Exclusively using RMS for all examinations could reduce carbon emissions by 85.6%. Clinicians had an overall positive attitude towards RMS. Key obstacles to use were poorly stocked rooms and insufficient variety of size.Discussion: The success of this pilot scheme is being built upon by investing in a greater variety of sizes of RMS for use in SHAC aiming for a 100% reusable system.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"151-154"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11773990/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142583144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The impact of concurrent HIV-infection on women with vulvar cancer: Comparison of clinical characteristics and outcome. 同时感染艾滋病毒对女性外阴癌患者的影响：比较临床特征和结果。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-02-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241287260

Jennifer L Butt, Judith S Jacobsen, Hannah M Simonds, Matthys H Botha

{"title":"The impact of concurrent HIV-infection on women with vulvar cancer: Comparison of clinical characteristics and outcome.","authors":"Jennifer L Butt, Judith S Jacobsen, Hannah M Simonds, Matthys H Botha","doi":"10.1177/09564624241287260","DOIUrl":"10.1177/09564624241287260","url":null,"abstract":"Background: HPV-related vulvar cancer is increasing in prevalence, especially in women living with HIV. Treatment of vulva cancer is based on evidence from HPV-independent cancers, which affect older women. The impact of HIV on vulvar cancer characteristics and treatment outcomes needs to be elucidated.Patients and methods: A retrospective observational study compared the clinical characteristics, treatment, and outcomes of 92 HIV-positive and 131 HIV-negative women with vulvar cancer at our institution. Using descriptive statistics, HIV-positive and negative patients were compared and Cox regression models were tested for differences in mortality and recurrence.Results: HIV-positive patients were 20 years younger than HIV-negative patients (p < 0.001). More than 50% of patients presented with advanced stage cancer, however this was independent of HIV-status. Although HIV infection was associated with poorer survival (p = 0.022); rates of cure (p = 0.933) and recurrence rates (p = 0.8) were similar in HIV-positive and negative women.Conclusions: Vulvar cancer occurs at a much younger age in women living with HIV. Awareness among HIV-positive women and health care providers would lead to diagnosis of vulvar cancer at an earlier stage. Treatment protocols for HPV-related vulvar cancer should not be altered due to HIV status and should take into consideration the young age of the patients.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"106-113"},"PeriodicalIF":1.4,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142365220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of sociodemographic characteristics on self-stigma among young MSM living with HIV in Yogyakarta, Indonesia: A cross-sectional study. 印度尼西亚日惹感染艾滋病毒的年轻男男性行为者的社会人口特征对自我污名化的影响：横断面研究。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-07 DOI: 10.1177/09564624241288286

Alessandro Alfieri, Nurwestu Rusetiyanti, Devi Artami Susetiati, Sunardi Radiono, Carla Raymondalexas Marchira, Satiti Retno Pudjiati

{"title":"Role of sociodemographic characteristics on self-stigma among young MSM living with HIV in Yogyakarta, Indonesia: A cross-sectional study.","authors":"Alessandro Alfieri, Nurwestu Rusetiyanti, Devi Artami Susetiati, Sunardi Radiono, Carla Raymondalexas Marchira, Satiti Retno Pudjiati","doi":"10.1177/09564624241288286","DOIUrl":"10.1177/09564624241288286","url":null,"abstract":"Background: Our study aimed to determine the role of sociodemographic characteristics on self-stigma among young men who have sex with men (MSM) living with HIV in Yogyakarta, Indonesia.Methods: This cross-sectional observational study was conducted from August-November 2022. Participants were recruited from outpatient clinics at Dr. Sardjito, Yogyakarta, Indonesia. The Indonesian version of the Berger HIV Stigma Scale measured self-stigma. The statistical analysis utilized a 95% confidence level and determined significance by p-values <0.05.Results: 72 young MSM were enrolled and completed questionnaires assessing sociodemographic and self-stigma. The average self-stigma score was 98.97. Education level was significantly associated with severe self-stigma in the bivariate analysis (p < .05). In the multivariate analysis, those with higher levels of education were significantly more likely to experience severe self-stigma (r = 2.938, p < .05). Employment status, family support, and education level were significantly associated with increased concerns in the disclosure, negative self-image, and public attitudes subscales (all p < .05).Conclusions: The results demonstrate associations between sociodemographic and self-stigma levels among young MSM living with HIV in Yogyakarta, Indonesia. Further research regarding the educational level, employment status, and family support that can influence the perception and quality of life of PLHIV may need to be carried out.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"72-79"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142380820","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association between motor neuron disease and HIV infection: A systematic review of case reports. 运动神经元疾病与艾滋病病毒感染之间的关联：病例报告的系统回顾。

IF 1.4 4区医学

International Journal of STD & AIDS Pub Date : 2025-01-01 Epub Date: 2024-10-03 DOI: 10.1177/09564624241288283

João Paulo Moreira Fernandes, Leonardo Peixoto Garcia, Felipe Araújo Gouhie, Raquel Campos Pereira, Diogo Fernandes Dos Santos

{"title":"Association between motor neuron disease and HIV infection: A systematic review of case reports.","authors":"João Paulo Moreira Fernandes, Leonardo Peixoto Garcia, Felipe Araújo Gouhie, Raquel Campos Pereira, Diogo Fernandes Dos Santos","doi":"10.1177/09564624241288283","DOIUrl":"10.1177/09564624241288283","url":null,"abstract":"Background: Motor neuron disease (MND) is a well-known group of neurodegenerative diseases, with amyotrophic lateral sclerosis (ALS) being the most common form. Since 1985, a possible association between MND/ALS and HIV infection has been described.Methods: We performed a systematic review of case reports and case series involving people living with HIV with MND/ALS through PubMed, Bireme, Embase, and Lilacs databases. The risk of bias was assessed using the Joanna Briggs Institute (JBI) Critical Appraisal Tool for Case Reports.Results: We analyzed 36 articles presenting 88 cases. The mean age was 41.6 years. Antiretroviral therapy (ART) was used by 89.8% and riluzole by 16.9%. First signs and symptoms were similarly present on cervical/upper (25%) and lumbosacral/lower limbs (23.9%), mostly with fasciculations (69.8%) and hyperreflexia (58.8%). MND had a progressive course in 32.9% patients and a clinical improve in 54.6% following ART. The mean survival of the 32 patients who died was 12.3 months and the mean survival of the living patients was 62 months. Respiratory failure was the main cause of death (35.7%).Conclusions: MND/ALS may present differently in the people living with HIV as a rapidly progressive disease in younger people but with the potential to improve weakness and survival through antiretroviral therapy.","PeriodicalId":14408,"journal":{"name":"International Journal of STD & AIDS","volume":" ","pages":"24-35"},"PeriodicalIF":1.4,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142371806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0