International journal of surgery最新文献

{"title":"Transformation of lung cancer patient education paradigm driven by large language models: a multidimensional performance study.","authors":"Chang Song, Chun-Yan Zhao, Tong Yang, Ren-Hao Liu, Zhi-Jun Chen, Mei-Song Liu, Qing-Dong Zhu, Jing-Song Chen","doi":"10.1097/JS9.0000000000003503","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003503","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A commentary on \"Systematic analysis and mechanistic investigation of cardiac adverse events associated with antibody-drug conjugates using FAERS database\".","authors":"Feiqi Wu, Fei Li, Yan Li","doi":"10.1097/JS9.0000000000003536","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003536","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of three-dimensional fast spin echo t2-weighted magnetic resonance imaging (cube) for evaluating the longitudinal spread of perihilar cholangiocarcinoma after endoscopic biliary stenting: a diagnostic study.","authors":"Keita Sonoda, Yuta Abe, Yoichi Yokoyama, Junya Tsuzaki, Shigeo Okuda, Akihisa Ueno, Ryo Takemura, Minoru Kitago, Yasushi Hasegawa, Shutaro Hori, Masayuki Tanaka, Yutaka Nakano, Hajime Okita, Masahiro Jinzaki, Yuko Kitagawa","doi":"10.1097/JS9.0000000000003438","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003438","url":null,"abstract":"<p><strong>Background: </strong>Although accurate assessment of the longitudinal tumor spread is vital for the resection of perihilar cholangiocarcinoma (PHC), endoscopic biliary stent (EBS) placement can make imaging difficult. This study evaluated the diagnostic performance of three-dimensional fast spin-echo T2-weighted MRI (Cube) compared with multidetector computed tomography (MDCT) for determining PHC extension before and after EBS placement.</p><p><strong>Materials and methods: </strong>This retrospective study included 91 patients who underwent surgical resection for PHC at a single center between 2016 and 2024 with available Cube and MDCT data. Four imaging scenarios were analyzed for each patient: MDCT without EBS, MDCT + EBS, Cube without EBS, and Cube + EBS. Radiological findings were compared with the pathological reference standard. Sensitivity, specificity, positive predictive value, negative predictive value, and accuracy were calculated for each scenario. Inter-reader agreement was determined using Cohen's kappa coefficient.</p><p><strong>Results: </strong>MDCT without EBS showed 79.1% accuracy in defining tumor extension, which dropped significantly to 30.2% after EBS placement (p<0.0001). Cube imaging showed 77.3% accuracy without EBS and 70.7% accuracy with EBS, significantly higher than MDCT with EBS (p<0.0001). The evaluability rate of MDCT decreased from 98% to 37% after stenting, whereas Cube retained an 85% evaluability rate with EBS. The inter-reader agreement was moderate to substantial for MDCT without EBS (κ = 0.74) and Cube without EBS (κ = 0.72) but declined for MDCT with EBS (κ = 0.34).</p><p><strong>Conclusion: </strong>Cube may be the preferred choice to guide surgical planning for PHC in patients without high-quality MDCT images before stent placement,. Collectively, these findings suggest that Cube could bring about a paradigm shift in imaging-based diagnosis of PHC.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of chatGPT on patient education of knee osteoarthritis: a preliminary study of 60 cases.","authors":"Yuanmeng Yang, Junqing Lin, Jinshan Zhang","doi":"10.1097/JS9.0000000000002494","DOIUrl":"10.1097/JS9.0000000000002494","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144127412","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Commentary on exploring potential plasma drug targets for cholelithiasis through multiancestry mendelian randomization.","authors":"Ji Pan, Yupeng Liu","doi":"10.1097/JS9.0000000000003286","DOIUrl":"10.1097/JS9.0000000000003286","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144954095","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endoscopic full-thickness resection for early gastric cancer: a multicenter retrospective study from the national early gastrointestinal cancer cohort (NEGCC).","authors":"Ke Han, Xiaoliang Zhu, Jiafeng Wang, Zhengcong Zhang, Jianhua Dai, Zhixin Liu, Wen Jia, Yaoqian Yuan, Kunming Lv, Miao Liu, Li Huikai, Ningli Chai, Zhuo Yang, Guiyong Peng, Qianqian Chen, Enqiang Linghu","doi":"10.1097/JS9.0000000000003472","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003472","url":null,"abstract":"<p><strong>Background: </strong>Endoscopic full-thickness resection (EFTR) enables en bloc resection of the entire gastric wall along with high-quality pathological specimens, offering a minimally invasive and organ-preserving therapeutic option for EGC patients at higher risk of submucosal invasion or malignancy. This multicenter retrospective study aimed to evaluate the clinical feasibility and short-term oncological outcomes of EFTR for local resection of EGC, and to explore its potential role as a curative or salvage treatment strategy.</p><p><strong>Methods: </strong>A multicenter retrospective study was conducted via the National Early Gastrointestinal Cancer Cohort. Patients aged 18-80 years with histologically confirmed EGC (TisN0M0 or T1N0M0) and at least one high-risk feature of lymph node metastasis underwent EFTR or laparoscopic-assisted EFTR with regional lymphadenectomy. Primary outcomes evaluated were technical success (en bloc resection and R0 resection. Additional observations included tumor recurrence, adverse events, and overall procedural efficiency.</p><p><strong>Results: </strong>A total of 21 patients with 22 EGC lesions were enrolled from four tertiary hospitals. The mean patient age was 60.90 ± 9.72 years, with a male predominance (85.71%). 13 patients (61.90%) underwent sft-SMIR and 8 (38.10%) underwent laparoscopy-assisted EFTR with regional lymphadenectomy. All lesions were successfully resected en bloc with R0 margins. No serious intraoperative complications were observed. Postoperative complications included gastroparesis, anastomotic leak, and peritonitis. During a median follow-up period of 14 months, no cases of recurrence, metastasis, or death were observed.</p><p><strong>Conclusions: </strong>EFTR is a feasible, minimally invasive strategy for EGC, offering high technical success and R0 resection rates. For lesions with potential lymph node metastasis, limited nodal dissection preserves gastric function while maintaining oncological safety. Although sample size and follow-up were limited, this study underscores EFTR's potential to expand individualized EGC treatment, warranting further prospective research for long-term validation. Longer-term oncologic outcomes remain to be elucidated and standard practice.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130096","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Incidence trends and surgical outcomes of synchronous liver metastasis across cancer types: a population-based cohort study.","authors":"Xinyue Zhang, Kai Lei, Tianhao Zhang, Kangbao Li, Yifan Zhang","doi":"10.1097/JS9.0000000000003555","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003555","url":null,"abstract":"<p><strong>Background: </strong>Liver metastasis (LM) is commonly detected in a range of malignancies, but data on the incidence trends and efficacy of surgery are lacking. We aimed to assess incidence trends of synchronous LM in various primary cancers, and determine whether surgery is justified for such patients.</p><p><strong>Methods: </strong>This retrospective population-based cohort study utilized data from 17 US registries of the Surveillance, Epidemiology, and End Results (SEER) program (2010-2021). Age-standardized incidence rates and annual percentage changes were used to character the incidence trends. Propensity score matching and multivariable Cox proportional hazards regression models were performed to examine the effect of LM surgery on overall survival (OS).</p><p><strong>Results: </strong>Among 4,180,870 cancer patients, 249,946 (6.0%) developed synchronous LM. The most common primary sites of LM were colorectum (25%), lung (24%), and pancreas (21%). The absolute number of LM patients increased between 2010-2021, with incidence increasing by 2.24% annually in 2010-2014, then decreasing by 0.69% annually until 2021. Notably, incidence of LM from colorectum, esophagus, and pancreas rose, whereas LM from lung and bronchus declined. Patients aged 60-79 were the major population suffering from LM, while significant increases were observed in those aged 20-39. Nearly 47.5% of LM cases were oligometastatic liver metastasis (oLM), indicating no metastasis to other organs. More than half of LM from small intestine, pancreas, colorectum, and stomach cancers were oligometastatic, whereas prostate, bone, and skin cancers developed multi-organ metastasis rapidly. Patients with oLM who underwent surgery of metastasis typically showed improved OS than those who did not (median OS, 6 months versus 44 months; 5-year survival rates, 7.4% versus 41%), especially for oLM from colorectum, pancreas, and small intestine cancers.</p><p><strong>Conclusion: </strong>The overall burden of LM increased between 2010 and 2021. There were significant differences in incidence trends, metastatic patterns, and surgical effectiveness of LM across various primary cancer types.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130516","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Semaglutide and improved spinal fusion outcomes: a correspondence.","authors":"Yuxue Qi, Xin Mou","doi":"10.1097/JS9.0000000000003490","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003490","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A commentary on \"Lactated Ringer's solution versus saline fluid resuscitation for reducing progression to moderate-to-severe acute pancreatitis: a systematic review and meta-analysis\".","authors":"Mingzhu Zhang, Juan Wen","doi":"10.1097/JS9.0000000000003541","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003541","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Selective portal vein occlusion with hepatic artery preservation reduces post-hepatectomy liver failure: a retrospective cohort study.","authors":"Jiming Ma, Jitao Wang, Liuqing Yang, Bingjun Tang, Canhong Xiang, Qiang Li, Pengfei Wang, Nan Jiang, Jianping Song, Yumei Li, Dongliang Yang, Yan Wen, Xuedong Wang, Shuo Jin, Jiahong Dong","doi":"10.1097/JS9.0000000000003548","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003548","url":null,"abstract":"<p><strong>Background: </strong>Current hepatic inflow occlusion techniques have limitations in effectively preventing post-hepatectomy liver failure (PHLF) from ischemia-reperfusion injury. Innovations in occlusion methods remain a critical area for advancement. This study investigated a hepatic inflow occlusion approach using selective portal vein occlusion (SPO) while maintaining hepatic arterial flow, aiming to evaluate its perioperative effects.</p><p><strong>Methods: </strong>Clinical data from consecutive patients who underwent hepatectomy between 2014 and 2024 were retrospectively collected. Postoperative outcomes were compared after a 1:1 ratio using propensity score matching (PSM) based on sex, age, body mass index, and Child-Pugh score using a fixed random seed. Univariate and multivariate logistic regression analyses were performed to identify risk factors for PHLF. Subgroup analyses were conducted to investigate the association between vascular occlusion strategies and the incidence of PHLF.</p><p><strong>Results: </strong>A total of 574 patients (192 SPO and 382 Pringle) were included. After PSM, 384 patients (192 SPO and 192 Pringle) were compared. PHLF was observed in 26 patients (6.8%). Hepatectomy with SPO was associated with a lower incidence of PHLF (3.1% vs. 10.4%, P = 0.026). No statistically significant difference was found in postoperative Clavien-Dindo grade III-IV complication rates between two occlusion groups (7.3% vs. 13.0%, P = 0.165). The optimal cut-off value of ICG-R15 for predicting PHLF was identified as 6.9% based on receiver operating characteristic (ROC) analysis, with an area under the curve (AUC) of 0.830 (95% CI: 0.735-0.922), a sensitivity of 88.5%, and a specificity of 66.5%. In multivariate logistic regression analysis, blood loss (p = 0.019), ICG-R15 > 0.069 (p<0.001), undergoing>hemihepatectomy (p<0.001) were identified as independent risk factors for PHLF. SPO was found to be an independent protective factor (p = 0.005). Subgroup analysis identified populations that benefit more from SPO, showing a significantly lower incidence of PHLF in patients aged <60 years (OR = 5.42, P = 0.019), males (OR = 5.06, P = 0.010), those with BMI≥23 (OR = 3.81, P = 0.049), without cirrhosis (OR = 4.9, P = 0.003), with benign disease (OR = 5.07, P = 0.031), and undergoing≤hemihepatectomy (OR = 5.16, P = 0.005).</p><p><strong>Conclusion: </strong>The occlusion approach of SPO while preserving hepatic arterial flow can significantly reduce the incidence of PHLF.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":10.1,"publicationDate":"2025-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145130832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}