International journal of surgery最新文献

{"title":"Commentary on \"P2X7 receptor promotes the growth and metastasis of gastric cancer by activating P13/AKT/GSK-3 beta signaling (experimental research)\" by Zhang et al., 2025.","authors":"Shayan Hamdollahzadeh","doi":"10.1097/JS9.0000000000003100","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003100","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative analysis of tip-bendable suction ureteral access sheath versus traditional sheath in retrograde intrarenal stone surgery: a systematic review and meta-analysis of comparative studies.","authors":"Zhenlang Guo, Zehuai Wen, Jiwan Qiu, Guixing Tang, Franky Leung Chan, Zhaohui Wang, Zunguang Bai, Junwei He","doi":"10.1097/JS9.0000000000002969","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002969","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review and meta-analysis seeks to evaluate the efficacy and safety of tip-bendable suction ureteral access sheaths (TBS-UAS) compared to traditional ureteral access sheaths (UAS) in retrograde intrarenal stone surgery (RIRS).</p><p><strong>Methods: </strong>A thorough literature search was performed across multiple databases, including MEDLINE (via PubMed), Cochrane Library, and Embase (via Ovid) for studies published until January 2025. We included randomized controlled trials (RCTs) and observational studies that reporting data on stone-free rates (SFRs), surgical duration, postoperative length of stay, and complication rates. Data were extracted and analyzed using random or fixed effects models to compute pooled relative risks (RRs) and mean differences (MD), along with their corresponding 95% confidence intervals (CIs).</p><p><strong>Results: </strong>Eight studies involving a total of 1,981 patients were included in the analysis. The TBS-UAS group exhibited a statistically significant enhancement in immediate SFR (RR = 1.57, 95% CI: 1.18-2.09) and SFR at one month postoperatively (RR = 1.24, 95% CI: 1.05-1.46) compared to the traditional UAS group. Additionally, the TBS-UAS was associated with a lower overall complication rate (RR = 0.41, 95% CI: 0.29-0.56) and a reduced incidence of fever (RR = 0.37, 95% CI: 0.25-0.53). No significant differences were found regarding surgical duration, postoperative length of stay, intraoperative bleeding, or mucosal injury between the two groups.</p><p><strong>Conclusion: </strong>The results indicate that TBS-UAS may provide notable advantages over conventional sheaths in RIRS, particularly in improving SFRs and reducing both overall and infectious complication rates. Further large-scale RCTs are needed to confirm these findings and assess long-term outcomes.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: multichannel deep learning prediction of major pathological response after neoadjuvant immunochemotherapy in lung cancer: a multicenter diagnostic study.","authors":"Qianru Yang, Li Hou, Jing Wang","doi":"10.1097/JS9.0000000000003109","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003109","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on \"Effect of remimazolam besylate vs propofol on incidence of postoperative delirium in older patients undergoing hip surgery: a randomized noninferiority trial\".","authors":"Wenwen Zheng, Xiaocou Wang, Xueyei Ye","doi":"10.1097/JS9.0000000000002454","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002454","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Immune competence and the nterpretation of P2X7R signaling in gastric cancer.","authors":"Shang Bian, Changquan Li, Houhong Wang","doi":"10.1097/JS9.0000000000003058","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003058","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"L-shaped association of selenium in blood metals mixtures with the incidence of liver fibrosis/cirrhosis: NHANES 2017-2020.","authors":"Lan Wang, Dunfeng Du, Xiaoqing Ying, Yukun Tang, Shangxin Dong, Hai Shang, Jipin Jiang, Bo Yang","doi":"10.1097/JS9.0000000000003102","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003102","url":null,"abstract":"<p><strong>Introduction: </strong>Trace elements in the environment are considered significant risk factors for chronic liver disease. However, the impact of blood metal levels on the incidence of liver fibrosis or cirrhosis has not been fully assessed. Our study investigated the correlation between metal mixture exposure and liver fibrosis/cirrhosis as well as the mediating effect between non-alcoholic fatty liver disease (NAFLD) and liver fibrosis/cirrhosis.</p><p><strong>Methods: </strong>We conducted a cross-sectional study using the National Health and Nutrition Examination Survey (NHANES) database from to 2017-2020. Transient elastography was used to identify NAFLD and liver fibrosis or cirrhosis. Various statistical models have been applied to evaluate the relationship between blood-metal mixtures and liver fibrosis/cirrhosis. The role of metal mixtures in NAFLD-associated liver fibrosis/cirrhosis was explored using a mediation analysis.</p><p><strong>Results: </strong>In the fully adjusted logistic models, selenium was negatively correlated with liver fibrosis (odds ratio [OR] = 0.219, P = 0.039) and cirrhosis (OR = 0.007, P = 0.003). In the weighted quantile sum (WQS) and quantile g-computation (qgcomp) models, selenium showed the highest contribution to liver fibrosis (0.544 and 0.578) and cirrhosis (0.538 and 0.630, respectively). Bayesian kernel machine regression (BKMR) and restricted cubic splines (RCS) models indicated an L-shaped association between selenium and liver fibrosis/cirrhosis. Selenium negatively mediated the relationship between NAFLD and liver fibrosis/cirrhosis according to the mediation analysis (-3.4% and -13.3%).</p><p><strong>Conclusions: </strong>Selenium shows an L-shaped relationship with liver fibrosis and cirrhosis and plays a negative mediating role in the association between NAFLD and liver fibrosis/cirrhosis. Blood selenium is a promising biomarker for chronic liver diseases, and supplemental selenium intake might contribute to the prevention and management of liver fibrosis/cirrhosis.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors affecting prognosis in pseudomyxoma peritonei patients after hyperthermic intraperitoneal chemotherapy and cytoreductive surgery: a systematic review and meta-analysis.","authors":"Xueyi Wei, Peng Liao, Xiuwen Chen, Wei Wu","doi":"10.1097/JS9.0000000000003107","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003107","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to identify and explore the risk factors affecting the prognosis of pseudomyxoma peritonei patients following hyperthermic intraperitoneal chemotherapy and peritoneal cytoreductive surgery.</p><p><strong>Methods: </strong>PubMed, Medline, Embase, Cochrane Library and registers were screened. The search timeframe was set before May 2025. We calculated each potential risk factor as risk ratio (RR) with 95% CI. Based on sample size, Egger's P value, and heterogeneity, the evidence was classified as high quality (class I), moderate quality (Class II or III), and low quality (Class IV). In addition, meta regression and sensitivity analysis were performed to explore potential sources of heterogeneity and stability of results.</p><p><strong>Results: </strong>A total of 20 studies were included, with a total of 6612 patients. Studies with high quality (Class I) evidence showed that pseudomyxoma peritonei patients with elevated levels of CA19-9 (RR, 2.30; 95% CI, 1.66-3.20, P = 0.00), CA125(RR, 3.39;95% CI, 2.29-5.01, P = 0.00) had worse prognosis. Moderate quality (Class II) evidence revealed significant associations between sex (RR, 1.73; 95% CI, 1.25-2.39, P = 0.00), CEA (RR, 3.16; 95% CI, 1.40-7.12, P = 0.01), PCI (RR, 1.05; 95% CI, 1.01-1.09, P = 0.03), CCS (RR, 2.10;95% CI, 1.61-2.76, P = 0.00), and postoperative outcomes. Moderate quality (Class III) evidence showed that ASA classification (RR, 1.19; 95% CI, 1.06-1.35, P = 0.00) and peritoneal histopathology (RR, 3.82; 95% CI, 2.25-6.49, P = 0.00) affected the prognosis. Studies with moderate quality (Class II) evidence showed no significant association between age (RR, 1.015; 95% CI, 0.997-1.033, P = 0.05) and prognosis after CRS-HIPEC.</p><p><strong>Conclusion: </strong>Male, ASA classification, high grade peritoneal histopathology and PCI are patient-related risk factors for prognosis after CRS-HIPEC, CA19-9, CA125 and CEA are tumor markers that affect prognosis. CCS is a risk factor associated with surgery. This study can guide clinicians to identify high-risk patients, implement more intensive post-operative monitoring, adjust surgical and chemotherapeutic plans and customize long-term follow-up strategies to improve prognosis.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707478","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on \"deep learning for kidney trauma detection: CT image algorithm performance and external validation. - experimental study\".","authors":"Ava Ghezel, Chista Sarira Arfaee","doi":"10.1097/JS9.0000000000002703","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002703","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implantation of integrated magnetically levitated biventricular assist devices (DuoCor) - a single center clinical experience.","authors":"Shijie Wang, Yixuan Wang, Jing Zhang, Shunzhou Yu, Fanwu Kong, Cheng Zhou, Nianguo Dong","doi":"10.1097/JS9.0000000000002879","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002879","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;End-stage heart failure remains a major global health challenge with high mortality. While heart transplantation is the gold-standard treatment, the scarcity of donor hearts necessitates alternative therapies. Left ventricular assist devices effectively support patients with end-stage left heart failure, but no mature biventricular assist devices (BiVAD) currently exist for those with biventricular failure. To address this gap, we developed the DuoCor BiVAD, a novel, integrated, magnetically levitated miniaturized biventricular assist system.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;This study reports the results of animal experiments and short-term clinical outcomes focusing on the DuoCor BiVAD. Animal experiments were conducted on three healthy adult male Chinese Merino sheep, with the endpoint being 2 months after device implantation, followed by retrieval and evaluation. Clinical data were collected from 8 patients who underwent DuoCor BiVAD implantation at ** Hospital between July 2024 and December 2024, with a median follow-up period of 6 months. During this period, device parameters, changes in patient heart function, and the occurrence of device-related adverse events (such as infection, thrombosis, and bleeding) were monitored.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;All animal implants achieved technical success (4.0 ± 0.7 h procedure time) with sustained 60-day hemodynamic stability and absence of device malfunction, thrombosis, or infection. In the clinical study, the median operative time was 5.1 hours, and the median postoperative hospital stay was 35 days. There were no in-hospital mortalities or device-related infections, and all patients were discharged home with DuoCor BiVAD support. During the 6-month postoperative follow-up period, one 81-year-old patient succumbed to frailty and COVID-19 infection two weeks post-discharge. The remaining seven patients survived with ongoing DuoCor BiVAD support, with no incidents of hemolysis, bleeding, device-related infection, or chronic renal insufficiency. This cohort includes one patient who developed right ventricular assist device thrombosis at 2 months post-implantation. Evaluation confirmed recovery of right ventricular function after the acute postoperative phase, prompting to discontinuation of right pump support. This patient subsequently maintained hemodynamic stability with left ventricular assist device support and experienced no further adverse events throughout follow-up.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;As a feasibility validation study of the first artificial biventricular assist device, DuoCor BiVAD demonstrated acceptable safety profiles during the short-term observation period. Although preliminary clinical outcomes were promising, these findings warrant cautious interpretation due to study size limitations and restricted follow-up duration. Furthermore, the device's integrated lightweight design and differential ventricular support technology confer adva","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Refining the LE8-multimorbidity-af nexus: methodological considerations for enhanced clinical translation.","authors":"Yidan Dong, Mingzhu Wang, Deyu Fu","doi":"10.1097/JS9.0000000000003113","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003113","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}