{"title":"Enhancing surgeon resilience through physical activity: a call to action.","authors":"Junfeng Zhang, Zhi Li, Xiaoyan Chen","doi":"10.1097/JS9.0000000000002476","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002476","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sike He, Yuan Wang, Ziqi Li, Nan Jiang, Guangxi Sun
{"title":"The first birthday of OpenAI's Sora: A promising but cautious future in medicine.","authors":"Sike He, Yuan Wang, Ziqi Li, Nan Jiang, Guangxi Sun","doi":"10.1097/JS9.0000000000002432","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002432","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Superior accuracy of femoral bone tunnel drilling in robot-assisted anterior cruciate ligament reconstruction: a multicenter, randomized, controlled trial.","authors":"Ling Zhang, Hansheng Hu, Wennuo Huang, Junjie Xu, Jinzhong Zhao, Wenyong Fei, Shaobai Wang","doi":"10.1097/JS9.0000000000002439","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002439","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the efficacy and safety for bone tunnel drilling in anatomic anterior cruciate ligament (ACL) reconstruction with the assistance of a surgical navigation robot system.</p><p><strong>Methods: </strong>A total of 79 patients were randomized to either surgical navigation robot group (robot group, n = 39) or traditional handheld locator group (control group, n = 40). The robot group underwent anatomic ACL reconstruction using a surgical navigation robot, while the control group underwent the procedure using a traditional handheld locator. Postoperative three-dimensional computed tomography was used to measure the tibial and femoral tunnel position, as well as the tibial and femoral tunnel length. The success rate of femoral tunnel positioning was defined as the proportion of cases in which the femoral tunnel was placed accurately within the ideal anatomical position.</p><p><strong>Results: </strong>The success rate of femoral tunnel positioning in the robot group was significantly higher than that in the control group (82.1% vs 50%, P = 0.003). The surgical time in the robot group was significantly longer than that in the control group (122.8 min ± 34.9 min vs 84.0 min ± 28.3 min, P = 0.05). The incidence rate of adverse events did not show statistical significance between the two groups (P = 0.830). There were no adverse events associated with the instruments or any serious adverse events, and no patients withdrew from the trial due to adverse events.</p><p><strong>Conclusions: </strong>The success rate for femoral tunnel positioning in anatomic ACL reconstruction was higher with surgical navigation robots compared to the traditional handheld locator. Surgical navigation robot systems are safe tools in anatomic ACL reconstruction surgery.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143996317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Sleep patterns, genetic susceptibility, and osteoarthritis risk: insights from the UK biobank and external validation in the xiangya osteoarthritis study.","authors":"Tingting Sha, Yilun Wang, Yuqing Zhang, Jian Zhang, Cong Lu, Jie Wei, Guanghua Lei, Chao Zeng","doi":"10.1097/JS9.0000000000002491","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002491","url":null,"abstract":"<p><strong>Background: </strong>Unhealthy sleep behaviors may contribute to osteoarthritis (OA), but their interrelated nature complicates evaluation and longitudinal studies examining the correlation between overall sleep behaviors and OA incidence are lacking. We explored the impact of sleep patterns on OA incidence and investigated whether genetic susceptibility plays a modifying role.</p><p><strong>Materials and methods: </strong>We analyzed 369,795 OA-free participants from the UK Biobank (discover cohort). A composite sleep score was derived from five behaviors: sleep duration, snoring, chronotype, daytime sleepiness, and insomnia symptoms. Incident site-specific OA were identified using ICD-codes. Genetic risk scores (GRS) were calculated. Cox regression models were used to estimated hazard ratios (HR) and 95% confidence intervals (CI). Finally, we verified the association between sleep patterns and OA in the Xiangya Osteoarthritis Study (validation cohort).</p><p><strong>Results: </strong>During a median follow-up of 11.9 years, 17,152 knee, 11,101 hip, and 2,714 hand OA cases were recorded. Participants with the lowest sleep scores (0-1) had significantly higher OA risks, showing a 32% increased risk for knee OA, 19% for hip OA, and 42% for hand OA. Poor sleep patterns were associated with elevated OA risk across all GRS categories, though not all associations reached statistically significant. For knee OA, HRs were 1.13 (95% CI: 0.95-1.34), 1.22 (95% CI: 1.11-1.34), and 1.16 (95% CI: 1.00-1.36) in the low, intermediate, and high GRS groups, with similar trends for hip and hand OA. The validation cohort further supported a dose-response relationship, with intermediate and poor sleep patterns linked to higher risks of knee (Ptrend = 0.026) and hand OA (Ptrend = 0.041), relative to healthy sleep.</p><p><strong>Conclusion: </strong>These findings demonstrates that an optimal sleep pattern is associated with a decreased OA risk, independent of genetic susceptibility. Our results emphasize the protective role of sleep in OA prevention and the importance of integrating sleep assessment into prevention strategies.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Neoadjuvant chemotherapy with albumin-bound paclitaxel plus cisplatin and capecitabine for locally advanced esophageal squamous cell carcinoma: a phase 2 clinical trial.","authors":"Wen Zhang, Xiaowei Chen, Liyan Xue, Zhichao Jiang, Dong Qu, Zhaoyang Yang, Jianjun Qin, Zhen Wang, Miaomiao Zhang, Yong Li, Aiping Zhou, Shugeng Gao","doi":"10.1097/JS9.0000000000002375","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002375","url":null,"abstract":"<p><strong>Background: </strong>Neoadjuvant chemotherapy is recommended for locally advanced esophageal squamous cell carcinoma (ESCC), but more effective regimens are needed to improve the outcomes. This study evaluates the efficacy and safety of neoadjuvant chemotherapy with albumin-bound paclitaxel plus cisplatin and capecitabine (APC regimen) for locally advanced ESCC.</p><p><strong>Materials and methods: </strong>This prospective single-center phase 2 clinical study involved patients with locally advanced ESCC (T2-4aN±M0) from May 19, 2020 to September 1, 2022. Patients received neoadjuvant chemotherapy with APC regimen for four cycles and then underwent radical esophagectomy. The primary endpoints were the pathologically complete response (pCR) rate. The secondary endpoints were the major pathological response (MPR) rate, radical resection rate (R0 resection rate), disease-free survival (DFS), event-free survival (EFS), overall survival (OS), and safety.</p><p><strong>Results: </strong>Eighty-two patients with locally advanced ESCC were enrolled in the trial. Of the 80 patients who underwent surgery, the R0 resection rate was 100%, and 23 patients achieved pCR, with a pCR rate of 28.7% (95% CI: 18.8%-38.6%). Fifty patients achieved MPR, with an MPR rate of 62.5% (95% CI: 51.9%-73.1%). The most common grade 3-4 treatment-related adverse events were neutropenia (25.6%), leukocytosis (14.5%), nausea (7.5%), and peripheral neurotoxicity (5.5%). Five patients developed complications within 1 month after surgery, including pneumonia (five patients, 6.3%), anastomotic fistula (one patient, 1.3%), and laryngeal recurrent nerve paralysis (one patient, 1.3%), all of which were grade 2. The local recurrence was observed in 8 (8.5%) patients, and distant metastasis in 10 (12.2%) patients. The 3-year DFS rate was 81.2%, the 3-year EFS rate 77.8%, and the 3-year survival rate 90%.</p><p><strong>Conclusion: </strong>Neoadjuvant treatment with APC regimen for locally advanced ESCC achieved excellent pCR rates and a well-tolerated safety profile. This combination chemotherapy could serve as one optional neoadjuvant treatment. (ClinicalTrials.gov: NCT04390958).</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Xiaoyan Li, Jingmin Bai, Xin Zhou, Ting Wang, Yuning Zhang, Yi Hu
{"title":"Diagnostic performance and safety for robotic-assisted bronchoscopy in pulmonary nodules: a systematic review and meta-analysis.","authors":"Xiaoyan Li, Jingmin Bai, Xin Zhou, Ting Wang, Yuning Zhang, Yi Hu","doi":"10.1097/JS9.0000000000002423","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002423","url":null,"abstract":"<p><strong>Background: </strong>Robotic-assisted bronchoscopy (RAB) is an emerging diagnostic tool that combines robotics and bronchoscopy. This meta-analysis aimed to comprehensively evaluate the performance and safety of RAB for pulmonary nodule diagnosis.</p><p><strong>Methods: </strong>PubMed, Embase, Cochrane Library, and Web of Science were searched from their inception up to 4 November 2024. The quality of the studies was assessed by the Quality Assessment of Diagnostic Accuracy Studies-2. Random and fixed effects models were used to estimate the pooled diagnosis yield in strict or intermediate criteria, sensitivity for malignancy, and complication rate of RAB in pulmonary nodule diagnosis, with rates (%) and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>In total, 27 cohort studies were included. The pooled diagnostic yields of RAB for pulmonary nodules were 69.6% (95%CI: 61.8%-76.8%) for strict criteria and 86.6% (95%CI: 83.7%-89.2%) for intermediate criteria, with a sensitivity for malignancy of 85.4% (95%CI: 83.0%-87.7%). The pooled complication rate was estimated to be 3.0% (total pneumothorax, 2.0%; pneumothorax that required intervention, 0.5%; bleeding, 0.1%). The diagnostic yields were different (P < 0.05) among subgroups of patients based on total number of biopsies (≤100 vs. >100; 83.6% vs. 69.6%), prevalence for malignancy (<60% vs. ≥60%; 66.6% vs. 83.1%), radial endobronchial ultrasound view (concentric vs. eccentric vs. invisible; 88.6% vs. 84.5% vs. 46.0%). A difference (P = 0.005) in sensitivity for malignancy was observed between the group with average lesion sizes ≤20 mm and the group with sizes >20 mm (86.4% vs. 77.5%).</p><p><strong>Conclusion: </strong>RAB may be effective and safe in pulmonary nodule diagnosis, offering promising prospects for clinical application. The heterogeneity of diagnostic yield may be driven by different diagnostic criteria. Moreover, the current studies of RAB in pulmonary nodule diagnosis are single-arm studies, and more large-scale randomized controlled trials are needed.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144034411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Letter to the Editor regarding \"The development and evaluation of nine obesity-based indices for gallstones in U.S. adults\".","authors":"Rui Du, Rui Zhong, Binghui Jin, Zhikun Lin","doi":"10.1097/JS9.0000000000002445","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002445","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143964661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Abubakar Nazir, Awais Nazir, Muhammad Shah Wali Jamal
{"title":"Photon-counting CT in abdominal vascular imaging: a feasible breakthrough over conventional CT?","authors":"Abubakar Nazir, Awais Nazir, Muhammad Shah Wali Jamal","doi":"10.1097/JS9.0000000000002478","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002478","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143998191","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fiona R Kolbinger, Nithya Bhasker, Felix Schön, Daniel Cser, Alex Zwanenburg, Steffen Löck, Sebastian Hempel, André Schulze, Nadiia Skorobohach, Hanna M Schmeiser, Rosa Klotz, Ralf-Thorsten Hoffmann, Pascal Probst, Beat Müller, Sebastian Bodenstedt, Martin Wagner, Jürgen Weitz, Jens-Peter Kühn, Marius Distler, Stefanie Speidel
{"title":"AutoFRS: an externally validated, annotation-free approach to computational preoperative complication risk stratification in pancreatic surgery - an experimental study.","authors":"Fiona R Kolbinger, Nithya Bhasker, Felix Schön, Daniel Cser, Alex Zwanenburg, Steffen Löck, Sebastian Hempel, André Schulze, Nadiia Skorobohach, Hanna M Schmeiser, Rosa Klotz, Ralf-Thorsten Hoffmann, Pascal Probst, Beat Müller, Sebastian Bodenstedt, Martin Wagner, Jürgen Weitz, Jens-Peter Kühn, Marius Distler, Stefanie Speidel","doi":"10.1097/JS9.0000000000002327","DOIUrl":"10.1097/JS9.0000000000002327","url":null,"abstract":"<p><strong>Background: </strong>The risk of postoperative pancreatic fistula (POPF), one of the most dreaded complications after pancreatic surgery, can be predicted from preoperative imaging and tabular clinical routine data. However, existing studies suffer from limited clinical applicability due to a need for manual data annotation and a lack of external validation. We propose AutoFRS (automated fistula risk score software), an externally validated end-to-end prediction tool for POPF risk stratification based on multimodal preoperative data.</p><p><strong>Materials and methods: </strong>We trained AutoFRS on preoperative contrast-enhanced computed tomography imaging and clinical data from 108 patients undergoing pancreatic head resection and validated it on an external cohort of 61 patients. Prediction performance was assessed using the area under the receiver operating characteristic curve (AUC) and balanced accuracy. In addition, model performance was compared to the updated alternative fistula risk score (ua-FRS), the current clinical gold standard method for intraoperative POPF risk stratification.</p><p><strong>Results: </strong>AutoFRS achieved an AUC of 0.81 and a balanced accuracy of 0.72 in internal validation and an AUC of 0.79 and a balanced accuracy of 0.70 in external validation. In a patient subset with documented intraoperative POPF risk factors, AutoFRS (AUC: 0.84 ± 0.05) performed on par with the uaFRS (AUC: 0.85 ± 0.06). The AutoFRS web application facilitates annotation-free prediction of POPF from preoperative imaging and clinical data based on the AutoFRS prediction model.</p><p><strong>Conclusion: </strong>POPF can be predicted from multimodal clinical routine data without human data annotation, automating the risk prediction process. We provide additional evidence of the clinical feasibility of preoperative POPF risk stratification and introduce a software pipeline for future prospective evaluation.</p><p><strong>Graphical abstract: </strong></p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143719358","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}