International journal of surgery最新文献

{"title":"A Commentary on \"effects of Dyclonine Mucilage and Compound Lidocaine Cream as Tracheal Catheter Lubricant on Postoperative Pharyngeal Complications After General Anesthesia\".","authors":"Fu-Shan Xue, Dan-Feng Wang, Xiao-Chun Zheng","doi":"10.1097/JS9.0000000000003117","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003117","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: \"Development and Validation of a Deep Learning Ultrasound Radiomics Model for Predicting Drug Resistance in Lymph Node Tuberculosis a Multicenter Study\".","authors":"Shuyi Liu, Xuewei Wu, Rui Zhang","doi":"10.1097/JS9.0000000000003118","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003118","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707471","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor: revisiting radiomics in IDH-wildtype glioblastoma-a focus on non-enhancing tumor subregions.","authors":"Ming Chen, Chuanqi Xu, Xiaotian Zhang","doi":"10.1097/JS9.0000000000003110","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003110","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The mechanisms of environmental pollutant acetyl tributyl citrate induced oral squamous cell carcinoma using network toxicology, molecular docking and molecular dynamics simulation.","authors":"Yijing Guo, Yuyan Liu, Yabing Chen, Siyu Du, Yi Zheng, Lei Wang","doi":"10.1097/JS9.0000000000002967","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002967","url":null,"abstract":"<p><p>The rising prevalence of Acetyl Tributyl Citrate (ATBC) as an environmental pollutant has raised considerable concern about its potential role in oral diseases. This study focuses on the effects of ATBC exposure on oral squamous cell carcinoma (OSCC), with the specific aim of identifying potential targets and elucidating the associated molecular mechanisms, employing network pharmacology, molecular docking, and molecular dynamics (MD) simulation. Relevant targets of OSCC were collected from the TTD, GeneCards, and OMIM databases. The ChEMBL, STITCH, TargetNet, and Swiss Target Prediction databases were utilized to screen ATBC compounds and identify associated compound targets. We selected 107 potential targets for ATBC-induced OSCC and extracted 22 core targets using STRING 12.0 and Cytoscape 3.9.1, including AKT1, HSP90AA1, ESR1, CASP3, BCL2, PPARG, MMP9, and EGFR. Gene ontology (GO) analysis revealed that ATBC-induced OSCC was associated with cell proliferation and apoptosis caused by exogenous chemicals. Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis revealed that ATBC participates in the cancer signaling pathway through Heat Shock Protein 90 Alpha Family Class A Member 1 (HSP90AA1), Epidermal Growth Factor Receptor (EGFR), and Matrix Metalloproteinase-9 (MMP9). Molecular docking and MD simulations indicate the high stability and reliability of ATBC binding to these core targets. This study elucidates the role of ATBC in the induction of OSCC and its underlying molecular mechanisms, offering significant support for uncovering the toxicological mechanisms of ATBC. Moreover, it provides a theoretical foundation for developing preventive strategies and therapeutic interventions for oral diseases associated with ATBC exposure.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inadvertent placement of thoracic stent-grafts in false lumen during aortic dissection surgery - unicentric analysis and systematic review.","authors":"Hsiu-Ming Lee, Ying Sheng Li, Mingli Levin Li","doi":"10.1097/JS9.0000000000003028","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003028","url":null,"abstract":"<p><strong>Background: </strong>The aim of this retrospective study and systematic review was to examine the causes, management strategies, and outcomes of thoracic endovascular aortic repair (TEVAR) stent graft misplacement in the false lumen (FL). Accordingly, we analyzed cases from our institution along with data from published articles.</p><p><strong>Materials and methods: </strong>This single-center retrospective study analyzed six TEVAR stent graft misplacement cases among 1227 patients who had an aortic dissection and underwent TEVAR at our hospital (2011-2024). Furthermore, a systematic search of PubMed, Embase, Web of Science, and Cochrane CENTRAL and ClinicalTrials.gov for relevant studies was performed. Outcome data on symptoms, clinical outcomes, placement method, management strategies, treatment quality, potential causes of misplacement, and factors related to oversight were independently extracted by two reviewers in a standardized manner.</p><p><strong>Results: </strong>A total of 35 cases from 23 studies, including 6 from our institution, were reviewed. TEVAR misplacement predominantly occurred in Type A dissections (62.9%) and in cases of anterogradely placed TEVAR stents (68.6%). Complications, mainly visceral malperfusion (48.6%), were reported in 77.1% of the cases. Intraoperative misplacement was more accurately detected by transesophageal echocardiogram (TEE) or intravascular ultrasound (IVUS) than by aortography alone (p < 0.001). Endovascular retrograde stent extension with or without septal fenestration was linked to improved survival (p = 0.018). Early symptom onset within 3 days and delayed treatment increased mortality (p = 0.029). Overall mortality was 28.6%, mainly due to multiorgan failure (80%).</p><p><strong>Conclusion: </strong>Although rare, accidental TEVAR stent graft placement in the FL markedly increases mortality. Despite seemingly acceptable survival rates, challenges in diagnosis and the potential for publication bias may lead to misleading conclusions. Clinicians must immediately administer comprehensive aortography, TEE, IVUS, or intraoperative computed tomography when they suspect an instance of accidental placement to ensure timely intervention.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessment of robotic versus laparoscopic gastrectomy for gastric cancer patients with intraoperative technical complexity a multicenter retrospective study.","authors":"Hua-Long Zheng, Ling-Hua Wei, Tai-Yuan Li, Li Zhang, Jun-Jun She, Bao-Qing Jia, Xin-Gan Qin, Shuang-Yi Ren, Hong-Liang Yao, Dong-Ning Liu, Han Liang, Fei-Yu Shi, Peng Li, Bo-Pei Li, Xin-Sheng Zhang, Kui-Jie Liu, Chao-Hui Zheng, Chang-Ming Huang, Ping Li","doi":"10.1097/JS9.0000000000002957","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002957","url":null,"abstract":"<p><strong>Background: </strong>While robotic gastrectomy (RG) is increasingly used in gastric cancer surgery, its potential advantages over laparoscopic gastrectomy (LG) in intraoperative technical complexity (ITC) cases remain debated.</p><p><strong>Methods: </strong>This retrospective cohort study included 3,534 patients with gastric cancer who underwent radical gastrectomy at eight high-volume hospitals. ITC was defined by any of the following criteria: operative time exceeding the third quartile, intraoperative estimated blood loss ≥ 400 mL, or conversion to open surgery. Propensity score matching (PSM) and inverse probability of treatment weighting (IPTW) were conducted to compare short- and long-term outcomes.</p><p><strong>Results: </strong>Patients with ITC comprised 25.9% (916/3534) of the cohort (RG: 260, LG: 656). After baseline adjustment, RG and LG groups were comparable in both PSM and IPTW cohorts. RG showed lower overall postoperative complications (11.5% vs. 20.1%, p = 0.003), particularly pneumonia (2.3% vs. 11.0%, p <0.001) and shorter postoperative hospital stay (9.33 ± 4.41 vs. 10.77 ± 5.91 days, p = 0.010) compared to LG. These differences remained significant after PSM and IPTW analysis. The 3-year Overall Survival (83% vs. 78.8%, p = 0.15), Disease-Free Survival (81.9% vs. 76.2%, p = 0.073), and cumulative recurrence risk (16.9% vs. 20%, p = 0.26) were comparable between RG and LG groups, consistent after PSM and IPTW. Multivariate analysis indicated that the surgical approach was not an independent factor influencing technical complexity.</p><p><strong>Conclusions: </strong>For patients with ITC, RG demonstrated superior short-term and comparable long-term outcomes than LG.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Burden trend and forecasting analysis of malignant skin melanoma from 1990 to 2021.","authors":"Xingkai Wang, Junwu Huang, Jianping Hu, Xiaolong Ma, Zhen Huang, Jiazhuang Zhu, Chunlin Zhang, Kunpeng Zhu","doi":"10.1097/JS9.0000000000002908","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002908","url":null,"abstract":"<p><p>Malignant skin melanoma (MSM) is a highly malignant skin tumor that poses a significant threat to public health worldwide owing to its high mortality and susceptibility to metastasis. We aimed to conduct a comprehensive, multifaceted, and methodical analysis of the burden trends regarding MSM patients across all ages. We acquired the prevalence, incidence, and disability-adjusted life-years (DALYs) data of all ages and age-standardized patients from 1990 to 2021 worldwide, spanning 204 nations, 21 regions, and 5 SDI areas, using the Global Burden of Disease (GBD) database. Additionally, we employed joinpoint regression analysis to get the average annual percentage changes (AAPCs) for the aforementioned metrics. Lastly, by combining data from several levels, we examined trends in MSM burden. In addition, we first predict the general trend of MSM over the next 15 years using the autoregressive integrated moving average (ARIMA) model. Based on the above studies, since the 1990s, the worldwide health burden of MSM has been steadily increasing. Across levels and populations, the burden of MSM varies significantly. More effective and targeted interventions need to be developed as a means of managing the MSM burden, thereby alleviating global public health pressures.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multimodal radiopathomics approach for predictions of prognosis and immunotherapy response in patients with GC: a multicohort retrospective study.","authors":"Wei Wang, Weicai Huang, Xianqi Yang, Cheng Fang, Hongkun Wei, Zhe Li, Liang Qiu, Rou Zhong, Chuanli Chen, Qingyu Yuan, Kangneng Zhou, Lin Wu, Zhicheng Xue, Zhiwei Zhou, Yuanfang Li, Yikai Xu, Guoxin Li, Zhenhui Li, Jingping Yun, Yuming Jiang","doi":"10.1097/JS9.0000000000002939","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002939","url":null,"abstract":"<p><strong>Background: </strong>Current TNM staging systems insufficiently predict individual prognosis and chemotherapy response in gastric cancer (GC). We aimed to develop and validate a radiopathomics signature (RPS) integrating computed tomography (CT) and pathological features to improve prognostic stratification and guide treatment decisions. Preliminary evaluation of immunotherapy response was also conducted.</p><p><strong>Methods: </strong>This retrospective multicenter analysis included 1,133 GC patients across three Chinese institutions. We integrated features extracted from CT images and H&E stain slides using ResNet-50 and HoverNet, encompassing radiomics, pathomics microenvironment, single-cell spatial distribution, and pathomics nucleus data, to develop the RPS. Prognostic performance was evaluated using area under the time-dependent curve (AUC) and C-index. Chemotherapy and immunotherapy benefits were determined using Kaplan Meier analysis.</p><p><strong>Results: </strong>The RPS demonstrated strong performance in predicting 5-year overall survival (OS), with AUCs of 0.928 (95% CI: 0.899-0.956) in the training cohort, and 0.857-0.917 in internal and external validation cohorts, showing improved prognostic accuracy compared with single-modality radiomics and pathomics models. The model can identify patients who could benefit from postoperative chemotherapy (HR: 11.751, P < 0.0001). Moreover, the RPS showed a preliminary but significant association with treatment response in the immunotherapy cohort (n = 64; HR: 3.651, P = 0.009). The nomogram combining RPS and TNM stage yielded good C-indexes of 0.79-0.84 for OS across cohorts.</p><p><strong>Conclusions: </strong>The RPS robustly predicts prognosis and chemotherapy benefit in GC patients and provides preliminary insights into immunotherapy response prediction, complementing the TNM staging system and helping to guide patient-specific treatment strategies.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707475","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Integrating immunomodulation and antibiotic stewardship in pediatric cholangitis: a commentary.","authors":"Shuai Jiang, Qian Dong, Xiwei Hao","doi":"10.1097/JS9.0000000000003074","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003074","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing accuracy: a comparative analysis of preoperative liver volumetry in living donor liver transplantation from a surgeon's perspective - a retrospective cohort study.","authors":"EunJin Choi, Seok-Hwan Kim","doi":"10.1097/JS9.0000000000003112","DOIUrl":"https://doi.org/10.1097/JS9.0000000000003112","url":null,"abstract":"<p><strong>Background: </strong>Accurate preoperative graft volume assessment is fundamental to the success of living donor liver transplantation (LDLT). Although manual and automated computed tomography (CT) volume measurement methods using various volumetric tools are widely used, their accuracy remains uncertain. This study aimed to compare various CT-based volumetric measurement methods for predicting actual graft weight (AGW) in LDLT and to identify specific dry weight correction factors for each method to improve clinical reliability.</p><p><strong>Materials and methods: </strong>A retrospective diagnostic accuracy study was performed on 109 patients who underwent LDLT between 2011 and 2024. Right liver volume was measured using automated (Philips Healthcare software), semi-automated (AnyVol software), and manual volumetry (PetaVision for clinics) methods. The optimal dry weight correction factor was calculated for each method.</p><p><strong>Results: </strong>The optimal dry weight correction factors were 0.89 for the automated method, 0.82 for the semi-automated method, and 0.88 for the manual method. After applying these correction factors, the semi-automated method yielded the highest coefficient of determination (R2 = 0.687, standard error = 91.939). The error ratio decreased significantly: from 11.30 ± 14.59% to -0.93 ± 12.98% for the automated method, from 20.51 ± 15.65% to -1.18 ± 12.83% for the semi-automated method, and from 11.89 ± 14.67% to -1.53 ± 12.91% for the manual method.</p><p><strong>Conclusions: </strong>Accurate prediction of AGW depends on applying optimal correction factors specific to each measurement method. All three methods showed high accuracy with the semi-automated method demonstrating the highest R2 and lowest SE, while the automated method exhibited the lowest error ratio. These findings support the use of cost-effective, software-based volumetry with tailored correction factors to improve donor safety and graft outcomes.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144707476","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}