International journal of surgery最新文献

{"title":"Comparison of clinical characteristics of different ventilation devices for one-lung ventilation in adults: a network meta-analysis.","authors":"Haisu Li, Hezhi Wang, Conglan Wang, Yuhan Huang, Rui Yuan, Xiaoyi Zhao, Ying Xu","doi":"10.1097/JS9.0000000000002378","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002378","url":null,"abstract":"<p><strong>Objectives: </strong>Different ventilation devices, including double-lumen tube (DLT), video DLT (VDLT), and various bronchial blockers (BBs), were used for one-lung ventilation (OLV). This study aimed to assess the clinical characteristics of 12 OLV devices to identify the optimal ventilation strategy for different situations.</p><p><strong>Methods: </strong>PubMed, Embase, Web of Science, and the Cochrane Library were searched following the PICOS principle to retrieve relevant randomized controlled trials (RCTs) up to 18 November 2023. Network meta-analysis was conducted using R 4.3.2, StataSE15, and Review Manager 5.3 software to compare the clinical characteristics of these OLV devices, including the quality of lung collapse, malposition rate, time for device placement, the success of the first intubation attempt, postoperative sore throat, and hoarseness.</p><p><strong>Results: </strong>In summary, this study involved 33 RCTs with a total of 2177 patients to evaluate the clinical characteristics of 12 ventilation devices. Compared to the Arndt BB, DLT provided higher lung collapse quality and was less prone to malposition. According to the Ranking probabilities, the VDLT had a shorter placement time, while the Coopdech BB (CBB) had a higher success rate on the first intubation attempt. The Cohen Flex-Tip BB resulted in less hoarseness, and the CBB had a lower incidence of sore throat.</p><p><strong>Conclusion: </strong>DLT demonstrated reliable lung collapse quality. VDLT allowed for quicker placement and continuous airway monitoring. BBs had fewer complications and were easier to place but had a higher risk of malposition. Therefore, choosing an OLV device depends on the patient's clinical status and surgical needs.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144024083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Perspectives on disposable and reusable surgical materials in laparoscopic surgery: a global survey amongst surgeons.","authors":"Myrthe M M Eussen, Stijn Bluiminck, Monique Chambon, Carys Batcup, Emma J Kooistra, Tim Stobernack, Frenk van Harreveld, Nicole D Bouvy, Philip R de Reuver","doi":"10.1097/JS9.0000000000002442","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002442","url":null,"abstract":"<p><strong>Background: </strong>Surgical practices generate substantial waste due to disposable materials. Reusable alternatives have the potential to substantially reduce emissions, yet their implementation has been slow. This study investigates reasons for this by examining surgeons' perspectives on using disposable and reusable materials during laparoscopic cholecystectomy (LC).</p><p><strong>Materials and methods: </strong>A survey, containing both quantitative and qualitative questions, targeted surgeons' perceptions of sustainable healthcare in general and reusable versus disposable instruments (trocars, clip applicators, drapes, and gowns) in LC. Quantitative data was analyzed by experience level, hospital type, and WHO-regions.</p><p><strong>Conclusion: </strong>The survey was completed by 594 surgeons from 75 countries. While 82.3% supported reducing surgery's environmental impact, only 48.7% considered sustainability when selecting instruments. Limited availability of reusables was a major issue, with only 52.3% having access to reusable trocars, and fewer than 30% to reusable drapes and gowns. Availability was reported to be lower in Europe compared to other WHO-regions. Availability, cost-effectiveness, and quality are reported as necessary factors for transitioning to reusable materials.</p><p><strong>Interpretation: </strong>Surgeons are willing to use more reusable surgical materials in LC, but limited access and quality issues are major concerns. These findings offer valuable international insights into the current use of reusables, empowering surgeons to advocate for improved access and quality while driving the development and adoption of sustainable surgical practices.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143997678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Trends and projections of the burden of gastric cancer in China and G20 countries: a comparative study based on the global burden of disease database 2021.","authors":"Peipei Yang, Wenjie Huang, Yuanyuan Xu, Yuhao Teng, Peng Shu","doi":"10.1097/JS9.0000000000002464","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002464","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to comprehensively compare and analyze the burden of gastric cancer and attributable risk factors in China and Group of Twenty (G20) countries from 1990 to 2021, based on the latest the Global Burden of Disease (GBD) 2021 study. It also predicts the trends in gastric cancer incidence, mortality, and disability-adjusted life years (DALYs) in China and G20 countries over the next 19 years.</p><p><strong>Methods: </strong>This observational longitudinal study utilizes data from the GBD 2021 study, employing indicators that include incidence, mortality, DALYs, age-standardized rates, and attributable risk factors to assess gastric cancer trends. The joinpoint regression model was used to calculate the annual average percentage change to determine long-term trends of significant changes in gastric cancer occurrence in China and G20 countries. The autoregressive integrated moving average model was employed to predict the burden trends of gastric cancer in China and G20 countries from 2021 to 2040.</p><p><strong>Results: </strong>In 2021, the age-standardized incidence rate (ASIR), age-standardized mortality rate (ASMR), and age-standardized DALYs rate (ASDR) (95% uncertainty interval) for gastric cancer in China were 29.053 (22.423-36.2), 21.509 (16.663-26.611), and 501.26 (387.291-627.976) respectively, indicating a decrease compared to 1990. The ASIR, ASMR, and ASDR for G20 countries in 1990 and 2021 were substantially lower than those of China during the same periods. Joinpoint regression analysis demonstrated a significant overall decline in the APC of gastric cancer in China and G20 countries from 1990 to 2021, although a short-term upward trend was observed in China from 1998 to 2004. Predictions indicate a downward trend in ASIR, ASMR, and ASDR for both China and G20 countries over the next 19 years. However, in terms of risk factors, the proportion of DALYs due to smoking and high sodium diets in China ranked first among G20 countries in 2021.</p><p><strong>Conclusion: </strong>Due to the implementation of preventive strategies, advancements in healthcare, and improved economic conditions, the incidence, mortality, and DALYs of gastric cancer in China have decreased. However, there remains a certain gap compared to G20 countries at the same time. In the future, China should develop more detailed prevention and control strategies targeting risk factors, tailored to men, women, and different age groups.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intersphincteric complex a potential metastasis niche in ultralow rectal cancer and prognostic significance of its complete excision following intersphincteric resection- a prospective cohort study.","authors":"Sen Yan, Minwei Zhou, Yiming Zhou, Zhongwen Zhou, Deyan Tan, Zhenyang Li, Jianhua Ding, Jianbin Xiang","doi":"10.1097/JS9.0000000000002487","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002487","url":null,"abstract":"<p><strong>Background: </strong>The precise anatomical plane and the pathological significance of circumferential resection margin integrity for ultralow rectal cancer remain inadequately defined. This article investigates the spatial architecture of the intersphincteric complex (ISC) and its clinical implications in ISS dissection for ultra-low rectal cancer.</p><p><strong>Materials and methods: </strong>Formalin-fixed hemipelvis specimens (n = 37) from the laboratory of applied surgical anatomy were analyzed by macroscopic dissection and multiplexed immunofluorescence to characterize anatomical features of the intersphincteric complex (ISC). Additionally, patients diagnosed with ultra-low rectal cancer (n = 221) between 2019 and 2024 were enrolled prospectively. Primary endpoints for the patient group included disease free survival (DFS), local recurrence free survival (LRFS) and overall survival (OS). Secondary endpoints involved the assessment of anorectal function using prospective questionnaires.</p><p><strong>Results: </strong>Anatomy and histologic research introduced the concept of the intersphincteric complex. Proportion of patients with tumor metastasis in the intersphincteric complex was 61/197 (30.96%), indicating that the intersphincteric complex represented a potential site for metastasis in ultra-low rectal cancer. Complete intersphincteric complex excision was associated with favorable disease-free survival (HR, 0.382 [95% CI, 0.187-0.781]; P = 0.008) and local recurrence-free survival (HR, 0.251 [95% CI, 0.085-0.741]; P = 0.012) in patients and no significant differences was found among three subgroups concerning Wexner scores and LARS scores.</p><p><strong>Conclusion: </strong>A systematic anatomical analysis of the intersphincteric complex clearly elucidated key structures facilitating for ultralow rectal cancer. The intersphincteric complex is frequently a site for tumor metastasis and complete intersphincteric complex excision conferring favourable prognosis in patients with ultralow rectal cancer.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143965513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting the critical roles of reactive microglia in traumatic brain injury.","authors":"Jing-Yu Zhao, Yang Zhou, Chao-Wen Zhou, Ke-Bin Zhan, Ming Yang, Ming Wen, Ling-Qiang Zhu","doi":"10.1097/JS9.0000000000002420","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002420","url":null,"abstract":"<p><p>Traumatic brain injury (TBI) triggers a complex neuroinflammatory cascade, with microglia serving as key regulators of both pathological damage and tissue structural restoration. Despite extensive research, the precise temporal evolution of microglial activation and its implications for long-term neurological outcomes remain incompletely understood. Here, we provide a comprehensive review of the molecular and cellular mechanisms underlying microglial responses in TBI, highlighting their role in neuroinflammation, neurogenesis, and tissue remodeling. We systematically compare clinical and preclinical TBI classifications, lesion patterns, and animal modeling strategies, evaluating their translational relevance. Furthermore, we explore the limitations of the conventional M1/M2 dichotomy and emphasize recent insights from single-cell transcriptomic analyses that reveal distinct microglial subpopulations across different injury phases. Finally, we discuss current therapeutic strategies targeting microglial modulation and propose future directions for neuroimmune interventions in TBI. By integrating findings from experimental and clinical studies, this review aims to bridge mechanistic insights with therapeutic advancements, paving the way for precision-targeted neuroimmune therapies.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144017172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unraveling the molecular mechanisms of PFOA in clear cell renal cell carcinoma through network toxicology and molecular docking strategies.","authors":"Lei Wang, Linhao Zong, Dake Cao, Miao Guan","doi":"10.1097/JS9.0000000000002461","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002461","url":null,"abstract":"<p><strong>Background: </strong>As Perfluorooctanoic Acid (PFOA) has been extensively utilized as a processing aid in the manufacture of non-stick coatings, waterproof materials, and other products, concerns regarding its adverse health effects have emerged. Epidemiological data revealed a strong correlation between renal cell carcinoma (RCC) and PFOA concentration, while animal experimental results also demonstrate the association between PFOA and RCC. However, the key targets and mechanisms underlying PFOA-induced RCC remain elusive. This study utilized network toxicology to elucidate the critical target genes and mechanisms of PFOA-induced clear cell RCC (ccRCC), the most prevalent RCC subtype.</p><p><strong>Methods: </strong>We retrieved potential PFOA targets from the Swiss Target Prediction database, ChEMBL, and STITCH, and identified RCC-related targets from GeneCards and OMIM. Transcriptomic data for ccRCC patients were obtained from The Cancer Genome Atlas Program (TCGA) to identify differentially expressed genes. We intersected genes from these datasets for construct a protein-protein interaction (PPI) network. Hub genes were identified from the network using MCODE and cytoHubba plugins in Cytoscape. A risk score based on these hub genes was developed for prognostic analysis, and molecular docking was applied to validate the interactions between PFOA and hub targets.</p><p><strong>Results: </strong>Intersection genes from these datasets, yielding 70 potential PFOA-induced ccRCC targets. Network analysis identified 7 hub genes-CYP2C9, CYP3A4, CYP1A1, CYP1A2, CYP2B6, CYP2C8, and ABCB1, and molecular docking confirmed PFOA's binding affinity to their corresponding proteins. Enrichment analysis using Gene Ontology (GO), Kyoto Encyclopedia of Genes and Genomes (KEGG), and Reactome databases on the 70 potential targets and 7 hub genes revealed four potential mechanisms of PFOA-induced ccRCC: abnormal xenobiotic metabolism and accumulation of toxic intermediates, disrupted lipid homeostasis, oxidative stress and reactive oxygen species (ROS) generation, and disrupted steroid hormone signaling.</p><p><strong>Conclusion: </strong>Our findings provide novel insights into PFOA-induced ccRCC mechanisms, with implications for risk assessment and environmental health.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor: individualized blood pressure regulation and acute kidney injury in older patients having major abdominal surgery: a pilot randomized trial.","authors":"Youyi Lu, Lin Li, Qingsong Zou","doi":"10.1097/JS9.0000000000002459","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002459","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deep learning diagnosis of hepatic echinococcosis based on dual-modality plain CT and ultrasound images: a large-scale, multicenter, diagnostic study.","authors":"Jie Zhang, Jihao Zhang, Haoze Tang, Yuan Meng, Xiong Chen, Jie Chen, Yajin Chen","doi":"10.1097/JS9.0000000000002486","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002486","url":null,"abstract":"<p><strong>Background: </strong>Given the current limited accuracy of imaging screening for Hepatic Echinococcosis (HCE) in under-resourced areas, the authors developed and validated a Multimodal Imaging system (HEAC) based on plain Computed Tomography (CT) combined with ultrasound for HCE screening in those areas.</p><p><strong>Methods: </strong>In this study, we developed a multimodal deep learning diagnostic system by integrating ultrasound and plain CT imaging data to differentiate hepatic echinococcosis, liver cysts, liver abscesses, and healthy liver conditions. We collected a dataset of 8979 cases spanning 18 years from eight hospitals in Xinjiang China, including both retrospective and prospective data. To enhance the robustness and generalization of the diagnostic model, after modeling CT and ultrasound images using EfficientNet3D and EfficientNet-B0, external and prospective tests were conducted, and the model's performance was compared with diagnoses made by experienced physicians.</p><p><strong>Results: </strong>Across internal and external test sets, the fused model of CT and ultrasound consistently outperformed the individual modality models and physician diagnoses. In the prospective test set from the same center, the fusion model achieved an accuracy of 0.816, sensitivity of 0.849, specificity of 0.942, and an AUC of 0.963, significantly exceeding physician performance (accuracy 0.900, sensitivity 0.800, specificity 0.933). The external test sets across seven other centers demonstrated similar results, with the fusion model achieving an overall accuracy of 0.849, sensitivity of 0.859, specificity of 0.942, and AUC of 0.961.</p><p><strong>Conclusion: </strong>The multimodal deep learning diagnostic system that integrates CT and ultrasound significantly increases the diagnosis accuracy of HCE, liver cysts, and liver abscesses. It beats standard single-modal approaches and physician diagnoses by lowering misdiagnosis rates and increasing diagnostic reliability. It emphasizes the promise of multimodal imaging systems in tackling diagnostic issues in low-resource areas, opening the path for improved medical care accessibility and outcomes.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143982854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Diagnostic consistency between computed tomography and adrenal vein sampling of primary aldosteronism: leading to successful curative outcome after adrenalectomy; a retrospective study\".","authors":"Youyi Lu, Lin Li, Qi Li","doi":"10.1097/JS9.0000000000002458","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002458","url":null,"abstract":"","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144010602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The development and validation of a risk stratification system for assessing axillary status after neoadjuvant therapy in node-positive breast cancer: a multicenter, prospective, observational study.","authors":"Jia-Xin Huang, Jing-Si Mei, Fei Chen, Jia-Hui Huang, Yu-Ting Tan, Yi-Wen Wu, Feng-Tao Liu, Shao-Dong Qiu, Cai-Gou Shi, Yao Lu, Xue-Yan Wang, Gui-Ling Huang, Yu-Ting Zhang, Min-Shan Chen, Xiao-Qinsg Pei","doi":"10.1097/JS9.0000000000002391","DOIUrl":"https://doi.org/10.1097/JS9.0000000000002391","url":null,"abstract":"<p><strong>Objective: </strong>It is not clear which procedure is most optimal for axilla after neoadjuvant therapy (NAT) in node-positive breast cancer patients. Accurately identifying patients with axillary pathologic complete response (pCR) is crucial to minimize the overtreatment of axilla. This study was designed to develop a risk stratification model for axillary pCR.</p><p><strong>Methods: </strong>In this multicenter, prospective, observational study, node-positive breast cancer patients who received NAT followed by axillary lymph node dissection (ALND) were enrolled between June 2021 and April 2024. We assessed the performance of breast shear wave elastography (SWE) utilizing virtual touch imaging quantification in determining axillary status across ultrasound (US) nodal stages following NAT. A predictive model incorporating axilla US nodal stage and breast SWE was developed using multivariate logistic regression analysis. Last, a simplified risk score was developed based on the calculated prediction probability from this model and validated in the external test cohort.</p><p><strong>Results: </strong>The axillary pCR rates were 52.53% in the training cohort (n = 257) and 51.79% in the external test cohorts (n = 195). Approximately 21.67% of US N0 cases were false negatives; 42.35% of US N1 cases were false positives. With SWE, the false negative rate was 11.53% in US N0 patients and false positive rate was 22.22% in US N1 patients. The model based on dual-modality US demonstrated strong discriminatory ability (AUC, 0.93), precise calibration (slope of calibration curve, 0.99), and practical clinical utility (probability threshold, 4.5-94.5%); the percentages of accuracy, sensitivity, and specificity were 87.94%, 88.52%, and 87.41%, respectively. Patients scoring 1 demonstrated a low axillary non-pCR rate (5.21%-6.97%), potentially reducing unnecessary ALND rate (17.12%-24.10%).</p><p><strong>Conclusions: </strong>The risk stratification model integrating axilla US and breast SWE demonstrated good performance for assessing axillary status after NAT in node-positive breast cancer and might provide guidance for less aggressive management for specific individuals.</p>","PeriodicalId":14401,"journal":{"name":"International journal of surgery","volume":" ","pages":""},"PeriodicalIF":12.5,"publicationDate":"2025-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002647","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}