International journal of pediatric otorhinolaryngology最新文献

{"title":"Evaluating utility of allergy testing in management of nasal obstruction following inferior turbinate reduction","authors":"Joseph Lee ,&nbsp;Logan F. McColl ,&nbsp;Molly O. Meeker ,&nbsp;Tony Satroplus ,&nbsp;Natalie Kelly ,&nbsp;Kevin Liu ,&nbsp;Amanda Onwuka ,&nbsp;Tendy Chiang","doi":"10.1016/j.ijporl.2024.112177","DOIUrl":"10.1016/j.ijporl.2024.112177","url":null,"abstract":"<div><h3>Introduction</h3><div>Allergic rhinitis (AR) within the pediatric population affects more patients than any other chronic disease. Inferior turbinate hypertrophy (ITH) is a common cause of nasal obstruction in children and is strongly associated with AR. Inferior turbinate reduction (ITR) surgery is used in patients with ITH who have failed medical management. While surgery is curative for most, there remains a subset of patients who continue to have symptoms of nasal obstruction despite ITR, which can cause discomfort and significant impacts on quality of life. Additionally, some patients with persistent disease go on to require revision surgery. The objectives in this study were to assess the impact of allergy testing results in patients undergoing ITR and evaluate if they predict long-term durability of surgical outcome.</div></div><div><h3>Methods</h3><div>A retrospective chart review of patients undergoing ITR between January and December of 2015 was performed. Data pertaining to demographics, allergy testing results, surgical technique, and medical management was collected. Patients who underwent concomitant procedures at the time of ITR were excluded. Data analysis included descriptive statistics, chi-squared tests, and <em>t</em>-test analyses.</div></div><div><h3>Results</h3><div>297 patients who underwent ITR were included for data analysis. Overall, 20.9 % of patients had recurrent nasal obstruction after ITR and 5.4 % required revision surgery. Among all included patients, 37.7 % underwent allergy testing of which 53 (47.3 %) tested positive and 54 (48.2 %) tested negative; results were unknown for 5 (4.5 %) patients. In patients with positive allergy tests, 36 % had recurrent nasal obstruction and 11 % required revision surgery. In patients with negative allergy tests, 41 % had recurrent nasal obstruction and 13 % required revision surgery. There were no significant associations among those with positive and negative allergy tests and recurrence of nasal obstruction or need for revision surgery. Patients with a documented clinical diagnosis of AR were more likely to have recurrence of nasal obstruction after surgery than those without (28 % vs 12 %, p = 0.001) and were more likely to require revision surgery (9 % vs 1 %, p = 0.001).</div></div><div><h3>Conclusions</h3><div>ITR is a reasonable choice for the treatment of nasal obstruction in children. However, there remains a subset of patients who have recurrent nasal obstruction following initial surgery. Allergy testing results do not appear to impact the rate of recurrent nasal obstruction or the need for revision surgery. Therefore, the utility of allergy testing may have a limited benefit in the management of nasal obstruction in children. However, a clinical diagnosis of allergic rhinitis does appear to be a prognostic factor for experiencing post-operative recurrent nasal obstruction and requiring revision surgery.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112177"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The global impact of scoliosis on tracheal abnormalities and ventilation needs in pediatric patients with tracheostomy tubes","authors":"Jessie Marcet-Gonzalez ,&nbsp;Ritu Sampige ,&nbsp;Jennifer N. Brown ,&nbsp;Janai Buxton ,&nbsp;Morgan McCarver ,&nbsp;Julina Ongkasuwan ,&nbsp;Elton M. Lambert","doi":"10.1016/j.ijporl.2024.112211","DOIUrl":"10.1016/j.ijporl.2024.112211","url":null,"abstract":"<div><h3>Purpose</h3><div>To describe the effects of scoliosis severity on the trachea in patients with a tracheostomy tube.</div></div><div><h3>Materials and methods</h3><div>A retrospective chart review of patients 21 years and younger with a tracheostomy and scoliosis between 2001 and 2019 was conducted at a single tertiary pediatric hospital. Patients with spine curvature from C6 – T3 (tracheal limits) were divided into two groups based on curvatures that were either greater than or equal to 30° (Group A) or less than 30° (Group B).</div></div><div><h3>Results</h3><div>Among the 59 patients who met the inclusion criteria, median age at tracheostomy tube placement was 1.45 years, median tracheostomy duration was 10.26 years, and 75 % were ventilator dependent. Group A encompassed 22 patients, and Group B included 37 patients. There were no significant differences in the following outcomes between Groups A and B: obstructed carina view (<em>p</em> = 0.095), tracheal irritation (<em>p</em> = 0.270), tracheal curvature (<em>p</em> = 0.113), inadequate tracheostomy tube fit (<em>p</em> = 0.323), tracheomalacia (<em>p</em> = 0.765), custom tracheostomy tube use (<em>p</em> = 0.113), or ventilator dependence (<em>p</em> = 0.109).</div></div><div><h3>Conclusion</h3><div>Most tracheostomy patients with scoliosis were ventilator dependent. Spine curvatures of 30° or greater from C6 to T3 did not significantly influence view of the carina, tracheal irritation, tracheal curvature, and tracheostomy tube fit. Further work is needed to analyze the effects of scoliosis on tracheal abnormalities with greater power and to determine the best tracheostomy tube fit via in-office tracheoscopy evaluations.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112211"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and evaluation of a combined fluency rules program (FRP) with parent-child interaction training for preschool children who stutter: A randomized controlled trial","authors":"Ebrahim Barzegar Bafrooei ,&nbsp;Morteza Farazi ,&nbsp;Saman Maroufizadeh ,&nbsp;Akbar Darouie","doi":"10.1016/j.ijporl.2024.112189","DOIUrl":"10.1016/j.ijporl.2024.112189","url":null,"abstract":"<div><h3>Introduction</h3><div>This study aimed to develop and evaluate the effectiveness of a combined Fluency Rules Program (FRP) with parent-child interaction training for preschool children with stuttering.</div></div><div><h3>Methods</h3><div>A randomized controlled trial was conducted with 49 preschool children who stuttered. Participants were randomly assigned to either the experimental group, which received the combined FRP with parent-child interaction training, or the control group, which received only the FRP. Both groups attended 45-min therapy sessions twice weekly for three months.</div></div><div><h3>Results</h3><div>According to the change score analysis, at posttest measurement, there were significant decreases in the stuttering severity scores in both groups, but intervention group had a greater decrease than control group (mean differences = 4.50, 95 % CI [3.55 to 5.45], P &lt; 0.001). The improvement (i.e., increase) in the “Severity of Stuttering and Impact on the Parents” scores in the intervention group was 1.49 (95 % CI [1.10 to 1.89], P &lt; 0.001) points higher than the control group. The similar result was obtained for “Parent's Knowledge and Confidence in Managing it” factor. There was no statistically significant difference in the “Impact of Stuttering on the Child” scores between control and intervention groups (P = 0.163).</div></div><div><h3>Conclusion</h3><div>The combined FRP with parent-child interaction training was more effective than the FRP alone in reducing the severity of stuttering and improving parental confidence.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112189"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is imaging necessary in pediatric patients with isolated tinnitus?","authors":"Zainab Balogun ,&nbsp;Tracy Cheng ,&nbsp;Amber D. Shaffer ,&nbsp;David Chi ,&nbsp;Dennis Kitsko","doi":"10.1016/j.ijporl.2024.112196","DOIUrl":"10.1016/j.ijporl.2024.112196","url":null,"abstract":"<div><h3>Objectives</h3><div>Tinnitus is a common otologic complaint which can range from bothersome to debilitating. Imaging is frequently utilized to rule out tumors, fractures, and other causes but can also cause significant medical and economic burden for patients. Furthermore, the pediatric population may require sedation for imaging. This study explored how commonly imaging was performed in pediatric patients with isolated tinnitus and whether imaging results affected clinical care.</div></div><div><h3>Methods</h3><div>A retrospective case series of 266 patients aged 0–22 years diagnosed with tinnitus at a tertiary children's hospital was performed. Patients with otologic complaints other than tinnitus were excluded. Logistic regression, Wilcoxon rank-sum tests, and log-rank survival analysis were used for statistical analysis.</div></div><div><h3>Results</h3><div>The mean age of tinnitus diagnosis was 13.4 years (IQR 10.8–16.7), 221/266 (83.1 %) of patients were white, and 139/266 (52.3 %) were male. In the 108 with details available, 29 (26.9 %) had pulsatile tinnitus. Twenty-one of two-hundred and sixty-six (7.9 %) had a history of migraines and 24/266 (9.0 %) had a history of psychiatric diagnosis. Seventy-four out of two-hundred and sixty-six (27.8 %) of patients completed CT and/or MRI imaging. Eleven out of forty-four (14.9 %) of those who underwent imaging had abnormal findings, and only 1 MRI and 1 CT showed new abnormal findings. Of note, the abnormal MRI and CT were of the same patient, and the CT was obtained as part of a trauma survey. Of the 64 patients with follow-up, 47 % of patients noted resolution of tinnitus. Patients with pulsatile tinnitus and a history of migraines were more likely to obtain imaging (OR = 8.14, 6.17; p &lt; 0.001, &lt;0.001, respectively). History of sinusitis, head/ear trauma, psychiatric diagnosis, and pulsatile tinnitus was not correlated with new abnormal imaging.</div></div><div><h3>Conclusions</h3><div>In pediatric patients with isolated tinnitus, imaging very rarely reveals new abnormalities which can impact clinical care. Additional research is needed to optimize resource utilization and identify cohorts of pediatric patients with tinnitus in whom imaging can be deferred.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112196"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"MED-EL Bonebridge implantation in pediatric patients age 11 Years and younger: Is it safe and effective?","authors":"Kaitlyn A. Brooks ,&nbsp;Anastasia Kolousek ,&nbsp;Erin K. Holman ,&nbsp;Sean S. Evans ,&nbsp;Nandini Govil ,&nbsp;Kristan P. Alfonso","doi":"10.1016/j.ijporl.2024.112198","DOIUrl":"10.1016/j.ijporl.2024.112198","url":null,"abstract":"<div><h3>Objective</h3><div>To present our experience with off-label MED-EL Bonebridge implantation in pediatric patients younger than 12 years of age and compare outcomes to pediatric patients 12 years and older.</div></div><div><h3>Methods</h3><div>Pediatric patients who underwent Bonebridge implantation were included in a retrospective cohort study and were categorized by off-label use (&lt;12 years) and ≥12 years at time of bone conduction implantation (BCI). Hearing outcomes were collected after implant activation, which was typically 4–8 weeks post-implantation. Mann-Whitney U tests were performed to assess for differences between audiometric outcomes. Significance was set at <em>p</em> &lt; 0.05.</div></div><div><h3>Results</h3><div>Twenty patients (25 implants) &lt; 12 years of age and 17 patients (23 implants) ≥12 years of age underwent BCI. Pre-BCI speech recognition threshold (SRT) was better for the older patient group (median 50 dB) than the younger patient group (median 60 dB). Post-BCI SRT, however, was significantly lower in the younger patient group (median 22.5 dB) as compared to the older patient group (median 35 dB), (<em>p</em> &lt; 0.001, <em>Z</em> = 3.1). The two groups performed similarly on age-appropriate wordlists presented at 50 dB HL in aided conditions (<em>p</em> &gt; 0.05, −1&lt;<em>Z</em> &lt; 1). Postoperative complication rate was low for both age groups (9 % vs 8 %) and operative time was similar for both groups of patients (<em>p=0</em>.96<em>,</em> Z<em>=</em>0.52).</div></div><div><h3>Conclusion</h3><div>Pediatric patients younger than 12 years showed similar or better audiometric benefit from off-label Bonebridge implantation when compared to older patients. Pediatric patients younger than 12 years can be considered Bonebridge implant candidates if clinically indicated; Bonebridge implantation in this age group appears safe and technically feasible.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112198"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142822152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radio-clinical assessment of crista fenestra during pediatric cochlear implantation","authors":"Saad Elzayat ,&nbsp;Hussein A. El-Shirbeny ,&nbsp;Ahmed Morshedy ,&nbsp;Islam Soltan ,&nbsp;Maurizio Barbara ,&nbsp;Edoardo Covelli ,&nbsp;Mona A. Abdel-Kareem ,&nbsp;Ashraf Fayed ,&nbsp;Fathi Baki ,&nbsp;Tawfiq Khurayzi ,&nbsp;Haitham H. Elfarargy","doi":"10.1016/j.ijporl.2024.112195","DOIUrl":"10.1016/j.ijporl.2024.112195","url":null,"abstract":"<div><h3>Objectives</h3><div>This study aimed to assess the ability of preoperative computed tomography (CT) to predict the crista fenestra (CF) type during cochlear implantation and correlate these types with intraoperative findings. This may allow for precise preoperative planning with better surgical outcomes.</div></div><div><h3>Study design</h3><div>A prospective observational study.</div></div><div><h3>Settings</h3><div>The study was done in multiple tertiary centers between September 2021 and March 2024.</div></div><div><h3>Method</h3><div>ology: We correlated the preoperative radiological type of the CF with the intraoperative CF type to evaluate the accuracy and sensitivity of the HRCT to predict the CF type. We also assessed the need for CF drilling in each case.</div></div><div><h3>Results</h3><div>Our study included 154 patients who underwent CI. They were 90 (58.4 %) males and 64 (41.5 %) females with ages ranging from 2.1 to 7.6 years, with a mean of 4.69 ± 1.19. The intra-class correlation coefficient between both radiological evaluators was 0.985, which indicated a high agreement between them. The intraoperative surgical types of CF were significantly related to the radiological types as the Spearman correlation coefficient was 0.976, and the <em>P</em>-value was &lt;0.001.</div></div><div><h3>Conclusions</h3><div>Our study revealed that preoperative CT is a precise tool for predicting the intraoperative type of CF during cochlear implantation type with a sensitivity of 96.67 % and an accuracy of 94.17 %. Moreover, drilling of the CF is recommended in type A3 and type B2 CF.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112195"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142863781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing topical nasal steroid application in adenoid hypertrophy: A computational fluid dynamics (CFD) analysis","authors":"Bigyan Raj Gyawali ,&nbsp;Ashutosh Kashyap ,&nbsp;Sanju Thapa ,&nbsp;Darshan Chaulagain ,&nbsp;Suyogya Shakya ,&nbsp;Niraj Kumar Kushwaha","doi":"10.1016/j.ijporl.2024.112205","DOIUrl":"10.1016/j.ijporl.2024.112205","url":null,"abstract":"<div><h3>Introduction</h3><div>Intranasal steroids are effective in managing adenoid hypertrophy in children, but the evidence regarding technique of use for optimal results is lacking.</div></div><div><h3>Methods</h3><div>CFD analysis, with discrete phase modelling was done to simulate nasal spray in nasal cavity and drug delivery in the region of adenoids. The findings were validated using a 3D model designed from CT scan of the same region.</div></div><div><h3>Results</h3><div>Our study shows that the maximum spray deposition in the adenoid region is with injection angle of 30° with the concentration value of 14 kg/m³.</div></div><div><h3>Discussion</h3><div>Nasal steroids have been found to be quite effective in symptoms reduction in children with adenoid hypertrophy. The current guidelines for technique of application are similar to that which has been validated for nasal pathologies. But the studies analyzing optimum drug delivery to the adenoids with variations in technique of application are lacking. This is the research gap we have tried to fill with our study.</div></div><div><h3>Conclusion</h3><div>The application of nasal steroids with nozzle inclined at 30° with respect to the floor of nose ensures maximum drug delivery to the adenoids and is likely to improve the efficacy of this treatment.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112205"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142854158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is COVID-19 infection during pregnancy a risk for congenital hearing loss?","authors":"Jane Sheehan ,&nbsp;Alison Jagger ,&nbsp;Kate L. Francis ,&nbsp;S. Ghazaleh Dashti ,&nbsp;Patrick Gornall ,&nbsp;Melinda Barker ,&nbsp;Valerie Sung ,&nbsp;Sergio Ruiz-Carmona ,&nbsp;Susan Baohm ,&nbsp;Zeffie Poulakis","doi":"10.1016/j.ijporl.2024.112191","DOIUrl":"10.1016/j.ijporl.2024.112191","url":null,"abstract":"<div><h3>Objective</h3><div>Infections during pregnancy can increase the risk of congenital hearing loss. This population-based study investigated the effect of birthing parent COVID-19 infection during pregnancy on risk of congenital hearing loss in infants.</div></div><div><h3>Methods</h3><div>Records of infants born in 2022 were reviewed via a retrospective clinical audit of a universal state-wide newborn hearing screening program in Victoria, Australia. The number and timing of COVID-19 infections during pregnancy were collected via self-report at the time of the hearing screen. Infant records (n = 75,330) were divided into birthing parent infection group (n = 25,547, 33.9 %), and non-infection group (n = 49,783, 66.1 %). Group differences in screen and diagnostic audiology results were estimated by general linear regression models with a binomial distribution.</div></div><div><h3>Results</h3><div>Birthing parent and infant characteristics were similar across groups. Comparable proportions of infants obtained a refer result on their newborn hearing screen, requiring referral to diagnostic audiology (infection group: 1.4 %, 95%CI 1.2–1.5 versus non-infection group: 1.3 %, 95%CI 1.2–1.4). The proportion of infants diagnosed with any type and degree of hearing loss was also similar (infection group: 0.6 %, 95%CI 0.5–0.7 versus non-infection group: 0.6 %, 95%CI 0.6–0.7).</div></div><div><h3>Conclusion</h3><div>This epidemiological study is the largest to date and demonstrates that infants whose birthing parent reported COVID-19 infection during pregnancy were not at increased risk of obtaining a refer result on their newborn hearing screen, nor at increased risk of congenital hearing loss. Specific protocols or guidelines to manage the newborn hearing screening pathway of infants born to a parent with COVID-19 during pregnancy are not supported by this study's findings.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112191"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142824084","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of type of delivery and anesthesia method to ABR results on newborn hearing screening","authors":"Semih Guler ,&nbsp;Ayse Sanem Sahli ,&nbsp;Murat Dogan","doi":"10.1016/j.ijporl.2024.112185","DOIUrl":"10.1016/j.ijporl.2024.112185","url":null,"abstract":"<div><h3>Objectives</h3><div>The aim of this study is to examine the effect of type of delivery and anesthesia method on the screening ABR test results of newborns within the scope of the Newborn Hearing Screening Program (NHCP) and to investigate the relationship between the test results and the relevant variables.</div></div><div><h3>Methods</h3><div>441 newborns were included in the study. Of these newborns, 221 constituted the control group (normal (vaginal) delivery), and 220 constituted the study group (cesarean section, delivery). In the study, all newborns whose hearing was evaluated within the scope of the Newborn Screening Program were screened twice. Screening ABR test results applied were compared considering the type of delivery (normal (vaginal) or cesarean section) and anesthesia method (spinal or general). The effects of variables such as the duration of the baby's separation (dissection) from the mother's womb, the duration of exposure to the anesthetic agent and the total duration of the surgical procedure were examined.</div></div><div><h3>Results</h3><div>As a result of the study, a statistically significant relationship was found between delivery type (normal (vaginal) or cesarean section) and anesthesia method (spinal or general) and first screening ABR test results (p &lt; 0.001). While there was a statistically significant difference (p &lt; 0.001) in terms of separation time from the mother's womb (p &lt; 0.001) and exposure to an anesthetic agent among the first test screening ABR results of newborns born under general anesthesia, there was no statistically significant difference (p &lt; 0.001) in terms of total surgical procedure time (p = 0.106) no difference was detected. There was no statistically significant difference between ABR test results and these three variables in newborns born under spinal anesthesia (p &gt; 0.05).</div></div><div><h3>Conclusions</h3><div>The type of delivery newborns and the anesthesia method used at delivery may affect the results of screening ABR applied within the scope of a newborn hearing screening protocol. For this reason, it is very important to perform screening tests at the most appropriate and correct time.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112185"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142828525","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of auditory pathways and comorbid inner ear malformations in pediatric patients with Duane retraction syndrome","authors":"Gamze Atay ,&nbsp;Burçay Tellioğlu ,&nbsp;Hilal Toprak Tellioğlu ,&nbsp;Nizamettin Burak Avcı ,&nbsp;Betül Çiçek Çınar ,&nbsp;Hande Taylan Şekeroğlu","doi":"10.1016/j.ijporl.2024.112207","DOIUrl":"10.1016/j.ijporl.2024.112207","url":null,"abstract":"<div><h3>Aims and objectives</h3><div>This study aimed to investigate the presence, type, and severity of hearing losses in individuals with Duane Retraction Syndrome (DRS), and to ascertain if there are anomalies in the auditory pathways at the brainstem level in DRS, believed to arise from aberrant interaction between cranial nerves and brainstem nuclei.</div></div><div><h3>Study design</h3><div>Cross-sectional observational study.</div></div><div><h3>Setting</h3><div>Tertiary referral centre.</div></div><div><h3>Patients</h3><div>The study group comprised 20 patients diagnosed with DRS, aged between 5 and 18 years, who underwent ophthalmological, otological and audiological follow-up at our clinic. The control group was established using data obtained from the previous work of Sanfins M.D., et al., 2022.</div></div><div><h3>Interventions</h3><div>Participants underwent tympanometry and pure tone audiometry after ophthalmological and otological examination. Patients with hearing loss underwent auditory brainstem response (ABR) testing, while patients with normal hearing underwent temporal CT and MRI to detect possible aetiology.</div></div><div><h3>Main outcome measures</h3><div>Tympanograms, air and bone conduction pure tone averages, latencies of wave I, III and V and interwave latencies as well as radiological findings on CT and MRI were noted.</div></div><div><h3>Results</h3><div>Profound sensorineural hearing loss was detected in two of the 20 patients. One of the patients with hearing loss had left-sided exo-Duane, cochlear aplasia with dilated vestibule (CADV) anomaly in the right ear and profound sensorineural hearing loss in the right ear. The other patient had bilateral exo-Duane, incomplete partition type I (IP-I) malformation in the right ear and profound sensorineural hearing loss in the right ear. There was no significant difference observed in the ABR latencies of wave I, III, and V, as well as the inter-wave latencies, between the control group and the individuals diagnosed with DRS who had normal hearing.</div></div><div><h3>Conclusions</h3><div>No statistically significant difference was found in auditory brainstem responses between the control group and patients with DRS without hearing loss. It can be speculated that Duane retraction syndrome and hearing loss do not share a common pathogenesis at the level of the brainstem. However, it should be noted that hearing loss may be associated with inner ear malformations in DRS patients.</div></div>","PeriodicalId":14388,"journal":{"name":"International journal of pediatric otorhinolaryngology","volume":"188 ","pages":"Article 112207"},"PeriodicalIF":1.2,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142894343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}