International Journal of Reproductive Biomedicine最新文献

{"title":"A treatment approach of severe vulvar edema in ovarian hyperstimulation syndrome patient: A case report.","authors":"Leila Sadeghi,&nbsp;Aliyeh Ghasemzadeh,&nbsp;Kobra Hamdi,&nbsp;Nazli Navali,&nbsp;Parvin Hakimi,&nbsp;Laya Farzadi","doi":"10.18502/ijrm.v21i7.13896","DOIUrl":"https://doi.org/10.18502/ijrm.v21i7.13896","url":null,"abstract":"<p><strong>Background: </strong>Ovarian hyperstimulation syndrome (OHSS) is a serious life-threatening complication of infertility treatment. Vulvar edema is a disease with various causes and frequent phenomena seen in physiological and pathologic conditions like pregnancy, inflammatory disorders, tumors, idiopathic reasons, and most importantly, in the severe form of OHSS.</p><p><strong>Case presentation: </strong>Here, we report a 26-yr-old woman with severe OHSS, recombinant follicle-stimulating hormone therapy. 8 days later, we observed a mild and asymmetrical swelling of the vulva with severe edema in the right labia. Due to the worsening of the vulvar edema even after 15 days of conservative treatment, hand massage and compressive bandaging of the vulva were performed, which caused rapid recovery within 20 min of the case.</p><p><strong>Conclusion: </strong>Treatment with a hand massage with lubricant gel followed by compressive bandaging resolved the vulvar edema immediately; it is an easy procedure without any adverse events.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 7","pages":"585-590"},"PeriodicalIF":1.3,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505693/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41131051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The comparison of pregnancy outcomes in fresh and frozen embryo transfer: A cross-sectional study.","authors":"Ramesh Baradaran Bagheri,&nbsp;Mahshid Bazrafkan,&nbsp;Abbas Sabour,&nbsp;Mina Ataei,&nbsp;Bita Badehnoosh,&nbsp;Banafsheh Mashak,&nbsp;Bahareh Khakifirooz,&nbsp;Ramin Moghaddam","doi":"10.18502/ijrm.v21i7.13891","DOIUrl":"https://doi.org/10.18502/ijrm.v21i7.13891","url":null,"abstract":"<p><strong>Background: </strong>The benefits of frozen embryo transfer (FET) vs. fresh embryo transfer for in vitro fertilization (IVF) have been discussed in previous studies.</p><p><strong>Objective: </strong>To determine and compare the pregnancy outcomes following FET and frozen embryo transfer in women who underwent assisted reproductive techniques.</p><p><strong>Materials and methods: </strong>In this cross-sectional study, 233 women candidates for IVF/intra cytoplasmic sperm injection who referred to the Kamali Training Medical Center, Karaj, Iran during 2019-2020 were evaluated in 2 groups of fresh (n = 127) and frozen (n = 106) embryo transfers. The rates of pregnancy outcomes including chemical and clinical pregnancy, live birth, preeclampsia, ectopic pregnancy, still birth, and pregnancy loss were compared between groups in 3 age subgroups (<math><mo><</mo></math> 25, 25-35, and 35-40 yr old).</p><p><strong>Results: </strong>No significant difference in terms of chemical and clinical pregnancy and live birth rates were observed between groups in women aged <math><mo><</mo></math> 25 yr. Chemical and clinical pregnancy and live birth rates were significantly higher in the FET group compared to fresh group in 25-35-yr-old women (p = 0.01, p = 0.03, and p = 0.01, respectively). In 35-40-yr-old women, no significant differences were observed in terms of chemical and clinical pregnancy rates, but live birth rate was found to be significantly higher in the FET group (p = 0.02). The pregnancy loss was lower in the FET group (p = 0.038).</p><p><strong>Conclusion: </strong>In conclusion, the FET method in women aged 25-35 yr significantly increases the chance of successful IVF/intra cytoplasmic sperm injection.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 7","pages":"551-556"},"PeriodicalIF":1.3,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505699/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41121460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The time course of nod-like receptor family pyrin domain containing 3 inflammasome complex expressions in the testis tissue of an experimental varicocele rat model: An experimental study.","authors":"Hamideh Fallah Asl,&nbsp;Farideh Jalali Mashayekhi,&nbsp;Adib Zendedel,&nbsp;Maryam Baazm","doi":"10.18502/ijrm.v21i7.13895","DOIUrl":"https://doi.org/10.18502/ijrm.v21i7.13895","url":null,"abstract":"<p><strong>Background: </strong>Varicocele is characterized by abnormal dilation of the testicular vein, which results in hypoxia, the accumulation of reactive oxygen species, and the production of proinflammatory cytokines. It seems that a group of cytosolic receptors named nod-like receptor family, pyrin domain containing 3 (NLRP3) inflammasome, is activated and involved in the pathogenesis of varicocele.</p><p><strong>Objective: </strong>We aim to determine the time course of NLRP3 inflammasome expression in the testis tissue following varicocele induction.</p><p><strong>Materials and methods: </strong>In this experimental study, 36 adult Wistar rats (8 wk, 200-250 gr) were used. For the varicocele induction, the left renal vein was partially ligated. The mRNA levels of NLRP3, apoptosis-associated speck-like protein containing a caspase recruitment domain, and caspase-1 were evaluated by real-time polymerase chain reaction at 1, 2, 4, 8, and 12 wk after varicocele induction.</p><p><strong>Results: </strong>Results showed that the gene expression of NLRP3 inflammasome component including NLRP3, apoptosis-associated speck-like protein containing a caspase recruitment domain, and caspase-1 did not alter during week 1, 2, 4, and 8 after operation (p = 0.09). 12 wk after varicocele induction, gene expression levels were significantly up-regulated (p = 0.02).</p><p><strong>Conclusion: </strong>Our data provides clear evidence that varicocele stimulates inflammasome activation in the testis tissue 12 wk after the operation, and this time is required for investigating NLRP3 activity in the varicocele rat model.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 7","pages":"577-584"},"PeriodicalIF":1.3,"publicationDate":"2023-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10505694/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41128402","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Overtreatment by hysterectomy for cervical intraepithelial neoplasia: Medico-legal aspects.","authors":"Camilla Cecannecchia,&nbsp;Fernanda Cioffi,&nbsp;Andrea Cioffi","doi":"10.18502/ijrm.v21i6.13639","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13639","url":null,"abstract":"The article abstract is not available","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"521-522"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407918/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of sensate focus technique and position changing on sexual function of women with deep-infiltrating endometriosis after surgery: A clinical trial study.","authors":"Parisa Tajik,&nbsp;Shadab Shahali,&nbsp;Roya Padmehr","doi":"10.18502/ijrm.v21i6.13638","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13638","url":null,"abstract":"<p><strong>Background: </strong>Endometriosis is a disease that affects women throughout their sexual life. Sexual health is, therefore, a major concern for these women.</p><p><strong>Objective: </strong>This study aimed to assess the effects of the sensate focus technique and position changing on the sexual function of women with deep-infiltrating endometriosis 3-6 months after surgery.</p><p><strong>Materials and methods: </strong>This clinical trial study was performed on 80 women with deep endometriosis, aged 18-45 yr, who were referred to the endometriosis clinic of Avicenna fertility center, Tehran, Iran for follow-up after surgery from January to September 2021. They were divided randomly into 2 groups. In the intervention group, 2-hr virtual training sessions were held and the control group only completed the questionnaires without any intervention. Sexual function was evaluated after 4 and 8 wk.</p><p><strong>Results: </strong>8 wk after the intervention, the mean score of sexual function in the intervention group was significantly improved (p <math><mo><</mo></math> 0.001). The mean total score of sexual function in the pre-intervention period reached from 24.16 to 28.31 in 4 wk after the intervention and 29.85, 8 wk after the intervention. The mean score of sexual pain during the follow-up periods was significantly improved in the intervention group (p <math><mo><</mo></math> 0.001).</p><p><strong>Conclusion: </strong>Sensate focus technique and sexual position changing improved sexual function in women with deep endometriosis after surgery.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"509-520"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Study of different doses of zinc oxide nanoparticles by intraperitoneal and gavage methods on testicular tissue in Wistar rats: An experimental study.","authors":"Saemeh Rezaei Larijani,&nbsp;Seyed Mohammad Hosseini,&nbsp;Behrang Ekrami","doi":"10.18502/ijrm.v21i6.13637","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13637","url":null,"abstract":"<p><strong>Background: </strong>Zinc oxide nanoparticles (ZnO-NPS) are widely used inhuman life; however, they do have side effects on human health.</p><p><strong>Objective: </strong>This study aimed to evaluatethedifferent doses of ZnO-NPS on testicular tissue.</p><p><strong>Materials and methods: </strong>35 male Wistar rats(10-12 wk, 220 <math><mo>±</mo></math> 20gr) were divided into 7 groups of 5, including the control group (gavaged distilled water daily), sham group (received intraperitoneal doses of distilled water twice a week). The group receivedintraperitoneal ZnO-NPS (25, 50, and 100 mg/kg body weight, twice a week), and gavage (150 and 200 mg/kg body weight daily). All stages of the test were performed in 4 wk then serum testosterone and tissue malondialdehyde, and ferric reducing antioxidant power levels were measured, also testes histopathological evaluation was performed.</p><p><strong>Results: </strong>Our results showed that a reduced cell population of spermatozoa was observed in the group that received 25 mg/kg ZnO-NPS, while a reduced cell population of spermatozoa, edema, hyperemia, and vacuolar degeneration were observed in the group that received 50 and 100 mg/kg ZnO-NPS. The maximum amount of lesions were observed in the dose of 200 mg/kg. The highest amount of ferric reducing antioxidant power and testosterone levels were observed in the control group. Also, a 100 mg/kg intraperitoneal dose of ZnO-NPS and 150 mg/kg oral dose of ZnO-NPS were suitable doses to create a model of male genital lesions.</p><p><strong>Conclusion: </strong>Nanoparticles are harmful factors for the reproductive system and consequently affect infertility, which requires the toxicity of the concentration of these nanoparticles to be evaluated and controlled.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"499-508"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407915/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9970804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of sexually transmitted infections on the cervical cytological abnormalities among Iranian women: A cross-sectional study.","authors":"Azam Shafaei,&nbsp;Seyyed Ali Akbar Shamsian,&nbsp;Mohammad Ghodsi,&nbsp;Fatemeh Sadabadi,&nbsp;Maryam Shahi","doi":"10.18502/ijrm.v21i6.13636","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13636","url":null,"abstract":"<p><strong>Background: </strong>Sexually transmitted infections (STIs) are one of the world's most severe health challenges. The existence of STIs such as human papillomavirus (HPV) might cause cervical cell changes leading to cervical cancer.</p><p><strong>Objective: </strong>This study aims to assess the association of STIs with cervical cytological abnormalities and genital warts among women in northeastern Iran.</p><p><strong>Materials and methods: </strong>This cross-sectional study was carried out on 190 women referred to the central laboratory of Academic Center for Education, Culture, and Research, Mashhad, Iran from March to July 2022. The presence of genital infections caused by <i>Chlamydia trachomatis</i>, <i>Neisseria gonorrhoeae</i>, <i>Mycoplasma genitalium</i>, and Herpes simplex viruses (1 and 2) were assessed using the real-time polymerase chain reaction method. HPV genital infection was detected based on the principles of reverse hybridization, and cellular changes in the cervix were examined by the liquid-based cytology technique.</p><p><strong>Results: </strong>The mean age of participants was 35.33 <math><mo>±</mo></math> 8.9 yr. 34 different HPV genotypes were detected in all HPV-positive cases, and the most common genotype was low-risk HPV6. No significant association was found between STIs and cervical cytology abnormalities. The prevalence rates of sexually transmitted pathogens among HPV-positive and HPV-negative individuals were 10.9 and 1.6%, respectively. The frequency of genital warts was significantly higher in cases with multiple infections of high- and low-risk HPV genotypes.</p><p><strong>Conclusion: </strong>High percentages of the participants with non-HPV STIs and HPV infection had normal cervical cytology. It is advised to use STIs and HPV diagnostic tests along with cytology examinations for cervical cancer screening.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"491-498"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407913/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9970798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pregnancy outcomes in women with adenomyosis, undergoing artificial endometrial preparation with and without gonadotropin-releasing hormone agonist pretreatment in frozen embryo transfer cycles: An RCT.","authors":"Marzieh Eslami Moayed,&nbsp;Ashraf Moini,&nbsp;Ladan Kashani,&nbsp;Maryam Farid Mojtahedi,&nbsp;Tawoos Rezaee,&nbsp;Hamed Tabasizadeh,&nbsp;Khadije Maajani,&nbsp;Nazila Yamini","doi":"10.18502/ijrm.v21i6.13635","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13635","url":null,"abstract":"<p><strong>Background: </strong>Selecting a suitable and preferable method for endometrial preparation in frozen embryo transfer (FET) cycles for women with adenomyosis is still challenging in infertility treatment.</p><p><strong>Objective: </strong>To compare 2 artificial endometrial preparation regimens with and without gonadotropin-releasing hormone agonist (GnRHa) pretreatment in women with adenomyosis undergoing FET cycles.</p><p><strong>Materials and methods: </strong>This randomized clinical trial study was conducted on 140 adenomyosis cases who underwent FET cycles at Arash Women's hospital, Tehran, Iran from May 2020 to March 2021. Participants were randomly allocated into hormonal replacement therapy (HRT) and HRT+GnRHa pretreatment groups (n = 70/each). Endometrial preparation with 2-6 mg daily estradiol was started in the HRT+GnRHa group, taking after down-regulation with the GnRHa. Within the HRT group, the same dose of estradiol was commenced within the early follicular stage. The main (chemical and clinical pregnancy rates) and auxiliary results (twin pregnancy, miscarriage, and live birth rates) were compared between groups.</p><p><strong>Results: </strong>The demographic characteristics and severity of adenomyosis, endometrial thickness, and pattern at starting progesterone administration were similar in the 2 groups, and triple-line endometrium was found to be the dominant pattern in both groups (p = 0.65). No significant differences were observed in chemical, clinical, and twin pregnancy rates as well as miscarriage and live birth rates between groups (p = 0.71, p = 0.81, p = 0.11, and p = 0.84, respectively). However, the total estrogen dose and duration of estrogen consumption were significantly higher in the pretreatment group (p = 0.001, and p = 0.003).</p><p><strong>Conclusion: </strong>These results indicated that the hormonal endometrial preparation with estrogen and progestin for FET cycles is as efficacious as a protocol involving preceding pituitary suppression with a GnRHa. Further large randomized clinical studies are required to confirm these findings.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"481-490"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976212","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transvaginal sonography and surgical findings in the diagnosis of endometriosis individuals: A cross-sectional study.","authors":"Roya Padmehr,&nbsp;Khadijeh Shadjoo,&nbsp;Arash Mohazzab,&nbsp;Atefeh Gorgin,&nbsp;Roxana Karegar,&nbsp;Parvin Jaberipour,&nbsp;Zahra Sehat,&nbsp;Narges Maleki","doi":"10.18502/ijrm.v21i6.13634","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13634","url":null,"abstract":"<p><strong>Background: </strong>Endometriosis is a challenging gynecological disease and a debilitating condition that profoundly affects the individual's quality of life. Besides pathological confirmation, diagnostic laparoscopy has been internationally accepted as the standard method to identify the accurate mapping of endometriosis. Transvaginal sonography (TVS) is the first non-invasive imaging modality to estimate the severity of endometriosis.</p><p><strong>Objective: </strong>This study aimed to evaluate the accuracy of TVS in affected women compared with surgical findings.</p><p><strong>Materials and methods: </strong>This retrospective cross-sectional study surveyed 170 women with deep infiltrating endometriosis (DIE) referred to the endometriosis part of the Avicenna Infertility Center, Tehran, Iran and they underwent TVS followed by laparoscopy. Recorded data of individuals under study in the medical database system were reviewed. Finally, the agreement rate was calculated for ultrasound reports and intraoperative (IO) findings regarding ovarian endometrium, ovarian adhesion, involvement of cul-de-sac, rectovaginal septum, and bowel and ureter.</p><p><strong>Results: </strong>170 women with DIE entered the study. The agreement of TVS and IO findings were 86.76% for left ovarian endometriosis and 70.86% for right ovarian endometriosis, 93.90% for left ovarian adhesion, and 88.90% for right ovarian adhesion, 88.90% for a cul-de-sac, and 84.82% for bowel nodules. The findings, based on a laparoscopic assessment of the pelvic floor, were completely compatible with ultrasound reports (100%).</p><p><strong>Conclusion: </strong>TVS allows a preoperative evaluation in planning the surgical policy associated. TVS is beneficial for dedicated mapping of DIE; thus, an expert radiologist can aid the surgeon in preoperative evaluation and IO management.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"471-480"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Women's needs in their journey towards motherhood via oocyte donation: A mixed methods systematic review.","authors":"Hamideh Jafari,&nbsp;Ali Taghipour,&nbsp;Hosein Ebrahimipour,&nbsp;Robab Latifnejad Roudsari","doi":"10.18502/ijrm.v21i6.13633","DOIUrl":"https://doi.org/10.18502/ijrm.v21i6.13633","url":null,"abstract":"<p><strong>Background: </strong>Given the significant changes in family formation through donation procedures, providing an optimal level of care that is responsive to the needs of mothers who get pregnant via oocyte donation is pivotal to improve their maternal role. Therefore, it is necessary to recognize the needs of oocyte donation mothers to address their specific needs.</p><p><strong>Objective: </strong>This study aimed to review the needs of women in their journey towards motherhood via oocyte donation.</p><p><strong>Materials and methods: </strong>In this systematic review, which followed the updated Joanna Briggs Institute's methodological guidance for conducting a mixed methods systematic review, the quantitative observational and qualitative studies were searched through databases including PubMed, Web of Science, PsycINFO, the Cochran Library, and Google Scholar search engine. Letters to the editor, commentaries, magazine articles, articles without full text and abstracts presented in congresses were excluded. All English-language articles related to the needs of oocyte donation mothers, without time limitation, were reviewed. The eligible studies were critically appraised independently by 2 researchers.</p><p><strong>Results: </strong>4649 records were identified from those 18 articles were finally included in the review. The needs of oocyte donation mothers comprised 8 categories: The need for special services in fertility clinics, the need to improve the quality of care, the need for emotional support and psychological consultation, information needs, the need for financial support, the need for disclosure counseling, educational needs, and the need for sociocultural and religious support.</p><p><strong>Conclusion: </strong>This review suggests various needs of oocyte donation mothers. The results can be used in carefully planning supportive programs for this vulnerable population.</p>","PeriodicalId":14386,"journal":{"name":"International Journal of Reproductive Biomedicine","volume":"21 6","pages":"451-462"},"PeriodicalIF":1.3,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10407919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9976217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}