International psychogeriatrics最新文献

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Comparative Clinical Outcomes of Patients with Diabetic Foot Infection Caused by Methicillin-Resistant Staphylococcus Aureus (MRSA) or Methicillin-Sensitive Staphylococcus Aureus (MSSA). 耐甲氧西林金黄色葡萄球菌 (MRSA) 或甲氧西林敏感金黄色葡萄球菌 (MSSA) 引起的糖尿病足感染患者的临床疗效比较。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-06-01 Epub Date: 2022-04-13 DOI: 10.1177/15347346221094994
Francisco Javier Álvaro-Afonso, Esther García-Morales, Mateo López-Moral, Luis Alou-Cervera, Raúl Molines-Barroso, José Luis Lázaro-Martínez
{"title":"Comparative Clinical Outcomes of Patients with Diabetic Foot Infection Caused by Methicillin-Resistant <i>Staphylococcus Aureus</i> (MRSA) or Methicillin-Sensitive <i>Staphylococcus Aureus</i> (MSSA).","authors":"Francisco Javier Álvaro-Afonso, Esther García-Morales, Mateo López-Moral, Luis Alou-Cervera, Raúl Molines-Barroso, José Luis Lázaro-Martínez","doi":"10.1177/15347346221094994","DOIUrl":"10.1177/15347346221094994","url":null,"abstract":"<p><p>Few studies have addressed the interaction of specific pathogens with clinical outcomes in patients with diabetic foot infection (DFI). Our study aim was to compare the clinical outcomes among patients with DFI caused by methicillin-resistant <i>Staphylococcus aureus</i> (MRSA) with cases caused by methicillin-sensitive <i>Staphylococcus aureus</i> (MSSA). We gathered the data of 75 consecutive patients admitted at specialized outpatients diabetic with mild or moderate DFI in which <i>S. aureus</i> was isolated from bone or soft tissue specimens in pure or as a part of the polymicrobial culture. Patients were divided into two groups: those with MRSA infection and those with MSSA infection. Patients with MRSA diabetic foot infections were significantly associated with male gender (86% vs. 64%, <i>P</i> = .029), higher SINBAD Classification Score (3.6 ± 0.99 points vs. 2.8 ± 1.06 points, <i>P</i> = .001), longer mean wound evolution [17.8 (3;29.5) weeks versus 9.1 (1;12) weeks, <i>P</i> = .008], bone involvement [18 (50%) versus 9 (23.1%), <i>P</i> = .015] and longer mean healing time [18.2(8;28) weeks versus 9.1 (1;12) weeks, <i>P</i> = .008]. In addition, male gender (OR 8.81, 95% CI 2.00-38.84) and SINBAD Classification Score (OR 2.70, 1.46-5.00) were identified as independent risk factors for MRSA DFI. Significant differences in the number of surgical procedures to resolve infection [15 (41.7%) versus 13 (33.3%), <i>P</i> = .456] or in the mean healing time after surgical treatment [10.5 weeks (6.7;16.5) versus 6.1 weeks (3;8.7), <i>P</i> = .068] were not observed among groups, suggesting that when treatment is based on early and surgical debridement, MRSA infections are not associated with worse prognosis. In conclusion MRSA DFI has importance in clinical outcomes such as time to healing. We propose that recent lines of research regarding the genetic virulence of strains of <i>S. aureus</i> could provide new insights into our results.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"14 1","pages":"392-401"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79103733","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Associations between anxious-depression and cognitive change and mild cognitive impairment: HCHS/SOL Study of Latinos-Investigation of Neurocognitive Aging. 焦虑抑郁与认知改变和轻度认知障碍之间的关系:拉丁美洲人的HCHS/SOL研究-神经认知衰老的调查。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-06-01 Epub Date: 2025-03-17 DOI: 10.1016/j.inpsyc.2025.100058
Natasha Z Anita, Roberto Gonzalez-Prado, Alejandra Morlett Paredes, Wassim Tarraf, Sayaka Kuwayama, Ariana M Stickel, Daniela Sotres-Alvarez, Linda C Gallo, Frank J Pendedo, Martha Daviglus, Fernando D Testai, Hector M González
{"title":"Associations between anxious-depression and cognitive change and mild cognitive impairment: HCHS/SOL Study of Latinos-Investigation of Neurocognitive Aging.","authors":"Natasha Z Anita, Roberto Gonzalez-Prado, Alejandra Morlett Paredes, Wassim Tarraf, Sayaka Kuwayama, Ariana M Stickel, Daniela Sotres-Alvarez, Linda C Gallo, Frank J Pendedo, Martha Daviglus, Fernando D Testai, Hector M González","doi":"10.1016/j.inpsyc.2025.100058","DOIUrl":"10.1016/j.inpsyc.2025.100058","url":null,"abstract":"<p><strong>Objectives: </strong>This study examined the associations between anxious-depression symptoms with cognitive change and prevalent mild cognitive impairment (MCI) in middle-aged and older Hispanics/Latinos.</p><p><strong>Methods: </strong>Participants were enrolled in the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA) and the Hispanic Community Health Study/Study of Latinos (HCHS/SOL). Anxiety and depression were measured at Visit 1 using the 10-item Spielberger State-Trait Anxiety Inventory and the 10-item Center for Epidemiologic Studies Depression Scale, with latent class analysis applied to derive anxious-depression phenotypes based on items from both scales. Cognitive tests were completed at Visits 1 and 2 (average 7-years follow-up), where change was assessed using a change index between Visit 1 and 2, and function was assessed at Visit 2. Prevalent MCI was assessed using National Institute on Aging diagnostic criteria. Regression models were used to investigate the association of anxious-depression phenotypes with cognitive function, change, and MCI.</p><p><strong>Results: </strong>In 6140 participants (mean age = 56.5 ± 8.1-years), three anxious-depression profiles were identified: low (62 %), moderate (30 %), and high (8 %). All three profiles were associated with cognitive function at Visit 2, where high and moderate phenotypes were associated with lower cognitive scores compared to low. Moderate and high anxious-depression phenotypes were associated with greater prevalence of MCI compared to low (OR [95 % CI] = 1.64 [1.25; 2.16] and OR = 1.62 [1.12; 2.33], respectively). We found no associations between cognitive change and anxious-depression phenotype.</p><p><strong>Discussion: </strong>Co-occurring elevated anxiety and depression symptoms were associated with lower cognitive function and increased prevalence MCI 7-years later, but not overall changes in cognitive function between Visit 1 and Visit 2.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100058"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143657059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Interpreting self-report measures about cognition: What matters and what to do with the data: A commentary on "Awareness of baseline functioning and sensitivity to improvement in older people with and without mild cognitive impairment receiving a computerized functional skills training program". 解读关于认知的自我报告测量:重要的是什么以及如何处理数据:关于“接受计算机化功能技能培训计划的有或无轻度认知障碍的老年人的基线功能意识和对改善的敏感性”的评论。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-06-01 Epub Date: 2025-05-12 DOI: 10.1016/j.inpsyc.2025.100082
Henry W Mahncke
{"title":"Interpreting self-report measures about cognition: What matters and what to do with the data: A commentary on \"Awareness of baseline functioning and sensitivity to improvement in older people with and without mild cognitive impairment receiving a computerized functional skills training program\".","authors":"Henry W Mahncke","doi":"10.1016/j.inpsyc.2025.100082","DOIUrl":"10.1016/j.inpsyc.2025.100082","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100082"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143966346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Geographical inequalities in dementia diagnosis and care: A systematic review. 痴呆诊断和治疗的地域不平等:一项系统综述。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-06-01 Epub Date: 2025-02-21 DOI: 10.1016/j.inpsyc.2025.100051
Clarissa Giebel, Megan Rose Readman, Abigail Godfrey, Annabel Gray, Joan Carton, Megan Polden
{"title":"Geographical inequalities in dementia diagnosis and care: A systematic review.","authors":"Clarissa Giebel, Megan Rose Readman, Abigail Godfrey, Annabel Gray, Joan Carton, Megan Polden","doi":"10.1016/j.inpsyc.2025.100051","DOIUrl":"10.1016/j.inpsyc.2025.100051","url":null,"abstract":"<p><strong>Background: </strong>People with dementia can be disadvantaged in accessing health and social care services for diagnosis and care depending on where they live (including rural vs suburban vs. urban; postcode; country). Without an existing comprehensive synthesis of the evidence to date, the aim of this systematic review was to explore the evidence on geographical inequalities in accessing services for dementia diagnosis and care.</p><p><strong>Methods: </strong>Five databases were searched in June 2024, including studies conducted in any country, published from 2010 onwards, and in English or German. Titles and abstracts, and then full texts, were screened by at least two reviewers each. Any discrepancies were resolved in discussion with a third reviewer. Data were extracted by two researchers and synthesised narratively.</p><p><strong>Results: </strong>From 1321 studies screened and 49 full texts read, 32 studies were included in the final review. Most studies were conducted in the US, followed by the UK. Geographical inequalities in dementia are most often evidenced in relation to availability and suitability of services in different regions within a country, or a lack thereof. People with dementia residing in rural areas often experience challenges in receiving a timely diagnosis and accessing health and social care. No research has addressed geographical inequalities in accessing residential care. Innovative models on improving efficiency and quantity of diagnosis rates in rural Canada and Australia emerged.</p><p><strong>Conclusions: </strong>Health and social care services in rural areas need to be increased and made more suitable to the needs of people with dementia. More research needs to explore inequalities experienced by people with rarer forms of dementia. National strategies to overhaul the health and social care system need to focus on the rurality issue and recommend strategies to improve service access.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100051"},"PeriodicalIF":4.6,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12149024/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143476618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Daily-life walking speed, running duration and bedtime from wrist-worn sensors predict incident dementia: A watch walk - UK biobank study. 日常步行速度,跑步时间和就寝时间从手腕上佩戴的传感器预测痴呆事件:一项手表步行-英国生物银行研究。
IF 4.3 2区 医学
International psychogeriatrics Pub Date : 2025-06-01 Epub Date: 2025-01-07 DOI: 10.1016/j.inpsyc.2024.100031
Lloyd L Y Chan, Maria Teresa Espinoza Cerda, Matthew A Brodie, Stephen R Lord, Morag E Taylor
{"title":"Daily-life walking speed, running duration and bedtime from wrist-worn sensors predict incident dementia: A watch walk - UK biobank study.","authors":"Lloyd L Y Chan, Maria Teresa Espinoza Cerda, Matthew A Brodie, Stephen R Lord, Morag E Taylor","doi":"10.1016/j.inpsyc.2024.100031","DOIUrl":"10.1016/j.inpsyc.2024.100031","url":null,"abstract":"<p><strong>Objective: </strong>To determine if wrist-worn sensor parameters can predict incident dementia in individuals aged 60 + years and to compare prediction with other tools.</p><p><strong>Design: </strong>Observational cohort study.</p><p><strong>Setting: </strong>Community PARTICIPANTS: The cohort comprised 47,371 participants without dementia, aged 60 + years, who participated in the UK Biobank study (mean age=67 ± 4 years; 52 % female).</p><p><strong>Measurements: </strong>Nineteen digital biomarkers were extracted from up-to-7-day wrist-worn sensor accelerometry data at baseline. Univariable and multivariable Cox proportional hazard models examined associations between sensor parameters and prospectively diagnosed dementia.</p><p><strong>Results: </strong>Median follow-up was 7.5 years (interquartile range: 7.0 to 9.0 years), during this time 387 participants (0.8 %) were diagnosed with dementia. Among the gait parameters, slower maximal walking speed had the strongest association with incident dementia (32 % decrease in hazard for each standard deviation increase) followed by lower daily step counts (30 % decrease) and increased step-time variability (17 % increase). While adjusting for age and sex, running duration, maximal walking speed and early bedtime were identified as independent and significant predictors of dementia. The multivariable prediction model performed comparably to the ANU-ADRI and UKB-Dementia Risk Score models in the UK Biobank cohort.</p><p><strong>Conclusions: </strong>The study findings indicate that remotely acquired parameters from wrist-worn sensors can predict incident dementia. Since wrist-worn sensors are highly acceptable for long-term use, wrist-worn sensor parameters have the potential to be incorporated into dementia screening programs.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100031"},"PeriodicalIF":4.3,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Apathy is distinct from depression or fatigue and is associated with poor physical health in an older community cohort. 冷漠与抑郁或疲劳不同,在老年社区人群中,冷漠与身体健康状况不佳有关。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-05-28 DOI: 10.1016/j.inpsyc.2025.100089
Fleur Harrison, Moyra E Mortby, Andrew R Lloyd, Adam J Guastella, Julian N Trollor, Perminder S Sachdev, Henry Brodaty
{"title":"Apathy is distinct from depression or fatigue and is associated with poor physical health in an older community cohort.","authors":"Fleur Harrison, Moyra E Mortby, Andrew R Lloyd, Adam J Guastella, Julian N Trollor, Perminder S Sachdev, Henry Brodaty","doi":"10.1016/j.inpsyc.2025.100089","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100089","url":null,"abstract":"<p><strong>Objectives: </strong>To estimate point prevalence of apathy in older adults, examine its overlap with depression and fatigue, and explore its associations with multimorbidity and objective markers of health.</p><p><strong>Design: </strong>Sydney Memory and Ageing Study, an Australian population-based cohort.</p><p><strong>Setting: </strong>Community dwellings between 2005-2007.</p><p><strong>Participants: </strong>1,030 older adults, without dementia, aged 70-90.</p><p><strong>Measurements: </strong>Apathy was classified using strict (=3) and standard (≥2) cutoff scores on the self-report Geriatric Depression Scale (GDS)-3A, and a validated cutoff score (>0) on the informant-report Neuropsychiatric Inventory. Depression was assessed with strict and standard cutoffs on the GDS-12D, and fatigue with the Assessment of Quality of Life-6D. Multimorbidity (≥2 chronic conditions; computed with and without cardiovascular conditions), physical performance (walking speed, sit-to-stand, lateral stability, grip strength), adiposity (BMI, waist circumference), blood pressure, cholesterol and glucose were assessed.</p><p><strong>Results: </strong>Prevalence of apathy on the self-reported measure was 15.8 % (strict cutoff) or 48.9 % (standard). Informant-reported apathy was lower (2.9 %). Prevalence of self-reported depression was 5.9 % (strict cutoff) or 15.8 % (standard), and fatigue 9.8 %. Apathy overlapped very little with depression or fatigue (κ = .18, 95 % CI .14-.21). Apathy was associated with multimorbidity (even when excluding cardiovascular conditions), adiposity, fasting blood glucose level and physical performance, but not blood pressure or cholesterol.</p><p><strong>Conclusions: </strong>Apathy is more common than depression or fatigue in dementia-free older adults. It does not typically co-occur with these symptoms, but is accompanied by poorer physical health, including multimorbidity and metabolic dysregulation. Apathy may be relevant for public health and an important consideration in clinical care.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100089"},"PeriodicalIF":4.6,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Musical Engagement of brain LObes in Alzheimer's Disease patients study (MELODY): A randomized controlled trial. 阿尔茨海默病患者脑叶的音乐参与研究(旋律):一项随机对照试验。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-05-24 DOI: 10.1016/j.inpsyc.2025.100087
Jacobo Mintzer, Rebecca Long, Arianne Fritts, Jane Joseph, Paul J Nietert, Noam Calev, Olga Brawman-Mintzer
{"title":"Musical Engagement of brain LObes in Alzheimer's Disease patients study (MELODY): A randomized controlled trial.","authors":"Jacobo Mintzer, Rebecca Long, Arianne Fritts, Jane Joseph, Paul J Nietert, Noam Calev, Olga Brawman-Mintzer","doi":"10.1016/j.inpsyc.2025.100087","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100087","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the effect of music exposure on global clinical impact, arousal, and brain network connectivity in subjects with moderate to severe Alzheimer's disease (AD).</p><p><strong>Design: </strong>This was a pilot, controlled, single-blind, randomized, cross-over study.</p><p><strong>Setting: </strong>The University Hospital Outpatient Clinic and Imaging Center and the Veterans Administration Research Facility.</p><p><strong>Participants: </strong>Ten participants aged between 55 and 90 years with moderate to severe AD, a Mini-Mental State Examination (MMSE) score of 5-20, and without neuropsychiatric symptoms of dementia were enrolled in the study.</p><p><strong>Intervention: </strong>Participants were exposed to both preferred music (PM) and nature sounds (NS). A randomization program was used to determine assignment order for either PM or NS to be delivered via over-ear headphones at Visit 1. Visit 2, which occurred approximately one week later, was identical to Visit 1, but the participants who were originally exposed to PM were exposed to NS and vice versa.</p><p><strong>Measurements: </strong>A modified version of the Alzheimer's Disease Cooperative Study Clinical Global Impression of Change (ADCS-CGIC) was the primary outcome measure and functional magnetic resonance imaging (fMRI) scans were used to evaluate brain network connectivity.</p><p><strong>Results: </strong>There was a clinically and statistically significant positive response to music stimulation in the primary outcome measure and in the secondary outcome measure, as well as a clear differentiation in brain network connectivity when individuals were exposed to PM versus NS. There was also a strong correlation between clinical changes and brain network connectivity changes as documented by fMRI.</p><p><strong>Conclusions: </strong>Music has the potential to be utilized as a non-invasive method to stimulate the brain of individuals with severe cognitive impairment in key functions TRIAL REGISTRATION: The trial was registered in ClinicalTrials.gov (ID: NCT05309369) by Jacobo Mintzer, MD, MBA.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100087"},"PeriodicalIF":4.6,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142684","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Neural network disruptions between default mode network and salience network in mild cognitive impairment with neuropsychiatric symptoms. 伴有神经精神症状的轻度认知障碍患者默认模式网络与突出网络之间的神经网络中断。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-05-23 DOI: 10.1016/j.inpsyc.2025.100092
Chenxi Pan, Renren Li, Xiao Yuan, Jing Ma, Wei Zhang, Xiaoran Zheng, Zhilan Tu, Ying Su, Zhiyuan Zhai, Fuchun Lin, Yunxia Li
{"title":"Neural network disruptions between default mode network and salience network in mild cognitive impairment with neuropsychiatric symptoms.","authors":"Chenxi Pan, Renren Li, Xiao Yuan, Jing Ma, Wei Zhang, Xiaoran Zheng, Zhilan Tu, Ying Su, Zhiyuan Zhai, Fuchun Lin, Yunxia Li","doi":"10.1016/j.inpsyc.2025.100092","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100092","url":null,"abstract":"<p><strong>Background: </strong>Neuropsychiatric symptoms (NPS) in mild cognitive impairment (MCI) are associated with accelerated Alzheimer's disease (AD) progression. Identifying multimodal brain imaging patterns associated with NPS in MCI may help understand pathophysiology correlates AD.</p><p><strong>Methods: </strong>This cross-sectional resting-state functional magnetic resonance imaging study included 376 participants: 130 MCI with neuropsychiatric symptoms (MCI+NPS), 154 MCI without neuropsychiatric symptoms (MCI-NPS), 92 cognitively normal (CN). NPS were assessed by the Neuropsychiatric Inventory Questionnaire (NPI-Q). Functional connectivity between default mode network (DMN) and salience network (SN) was compared among MCI+NPS, MCI-NPS and CN. Then, the morphometric measurements of abnormal node in default mode and salience networks was explored. Furthermore, correlation analysis was performed to investigate the relationship between NPS and functional and structural alterations in DMN and SN in MCI.</p><p><strong>Results: </strong>In the MCI+NPS group, the most frequently endorsed NPS was anxiety (46.2 %), the less prevalent NPS was euphoria/elation (1.44 %). Compared with the MCI-NPS group, there was abnormal FC between medial prefrontal cortex (mPFC) and anterior cingulate cortex (ACC) (P < 0.05) in the MCI+NPS group, which was significantly associated with total NPI-Q score (r = 0.244, p = 0.000), affective symptoms (r = 0.212, p = 0.000), and hyperactivity symptoms (r = 0.196 p = 0.000). The mPFC area of MCI-NPS group was smaller than that of CN group (p < 0.05), and the area of mPFC was significantly associated with hyperactivity symptoms in MCI group.</p><p><strong>Conclusions: </strong>Dysfunction of DMN and SN may partly contribute to the NPS in MCI patients, especially affective symptoms and hyperactivity symptoms. Our results complement the evidence linking NPS with Alzheimer's disease biomarkers.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100092"},"PeriodicalIF":4.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144142651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The influence of social interactions on mood in residents with dementia in green care farms: An observational study using ecological momentary assessments. 社会互动对绿色护理农场痴呆居民情绪的影响:一项使用生态瞬时评估的观察性研究。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-05-23 DOI: 10.1016/j.inpsyc.2025.100091
Laura Frissen, Sil Aarts, Katharina Rosteius, Bram de Boer, Andrea Gabrio, Hilde Verbeek
{"title":"The influence of social interactions on mood in residents with dementia in green care farms: An observational study using ecological momentary assessments.","authors":"Laura Frissen, Sil Aarts, Katharina Rosteius, Bram de Boer, Andrea Gabrio, Hilde Verbeek","doi":"10.1016/j.inpsyc.2025.100091","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100091","url":null,"abstract":"<p><strong>Background: </strong>Social connections are important for the quality of life of individuals living with dementia. As dementia progresses, maintaining these connections becomes challenging: especially in nursing homes, social interactions are often reduced. Small-scale, homelike environments such as green care farms (GCFs) may provide opportunities to facilitate social interactions. However, research on the characteristics of social interactions and their effects on mood is limited in these settings. This paper explored social interactions and their impact on mood over time in individuals with dementia living in GCFs.</p><p><strong>Methods: </strong>This observational study used ecological momentary assessments to gather repeated measurement data on individuals' experiences in everyday environments. The data were collected for a total of 151 residents living at four GCFs in the Netherlands. The residents' social interactions and mood were assessed using the Maastricht Electronic Daily Life Observation Tool (n = 4868 observations).</p><p><strong>Results: </strong>Social interactions occurred in less than half of the observations, indicating that residents spent the other half of their day without social interactions. The most common interactions included one resident and another person (e.g., staff members or other residents); these interactions were primarily positive. Overall, having social interactions was significantly related to a higher mood. However, social interactions did not have a significant effect on subsequent mood.</p><p><strong>Conclusions: </strong>The results highlight the importance of social interactions for residents' mood. Long-term care organizations should facilitate opportunities for meaningful social interaction to support the immediate mood and thus the well-being of residents with dementia.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100091"},"PeriodicalIF":4.6,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144141934","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dementia training for healthcare professionals: A systematic policy and evidence review. 对医疗保健专业人员的痴呆症培训:系统的政策和证据审查。
IF 4.6 2区 医学
International psychogeriatrics Pub Date : 2025-05-19 DOI: 10.1016/j.inpsyc.2025.100088
Sedigheh Zabihi, Saskia Delray, Malvika Muralidhar, Sube Banerjee, Clarissa Giebel, Karen Harrison Dening, Yvonne Birks, Rachael Hunter, Mohammed Akhlak Rauf, Charlotte Kenten, Madeleine Walpert, Claudia Cooper
{"title":"Dementia training for healthcare professionals: A systematic policy and evidence review.","authors":"Sedigheh Zabihi, Saskia Delray, Malvika Muralidhar, Sube Banerjee, Clarissa Giebel, Karen Harrison Dening, Yvonne Birks, Rachael Hunter, Mohammed Akhlak Rauf, Charlotte Kenten, Madeleine Walpert, Claudia Cooper","doi":"10.1016/j.inpsyc.2025.100088","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100088","url":null,"abstract":"<p><strong>Objective: </strong>To review the effectiveness of healthcare professionals' dementia training and consider implications for policy and practice.</p><p><strong>Design: </strong>Systematic and policy review SETTING: Healthcare services PARTICIPANTS: Healthcare professionals INTERVENTION: Training MEASUREMENTS: We searched electronic databases for primary research studies (2015-2024) evaluating dementia training for healthcare professionals. We assessed risk of bias using the Mixed Methods Appraisal Tool, prioritising studies scoring 4 + , of interventions supported by Randomised Controlled Trial evidence; reporting outcomes using Kirkpatrick's framework. To explore how evidence might translate to practice, using England as a case study, we reviewed relevant policies and consulted professional stakeholders.</p><p><strong>Results: </strong>We reviewed 63 primary research studies. One met priority criteria; it evaluated a Train-the-Trainer (TTT), team-based reflective practice model, which improved primary care nurses' and doctors' learning, and self-reported practice over ≥ 3 months. Higher quality, controlled studies evaluated a TTT programme for hospital staff, improving client outcomes (agitation) over ≤ 5 days; an expert-led two-day interactive training for inpatient nurses that reduced role strain; and expert-led, nine-week, occupational therapy-derived training programme that improved retirement community staff strategies for client activity engagement. Sixteen policies and related documents highlighted concerns about limited implementation of the Dementia Core Skills Education and Training Framework (DCSETF). Eight focus group attendees considered time a limiting factor to evidence implementation, but valued group training to share experiences; and TTT models to enable tailoring to local contexts.</p><p><strong>Conclusions: </strong>By increasing reach of dementia training and embedding learning in practice, Train-the-Trainer models can increase care quality and support evidence-based policy implementation.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100088"},"PeriodicalIF":4.6,"publicationDate":"2025-05-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144110614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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