International psychogeriatrics最新文献

{"title":"Potentially inappropriate medications and treatment adherence in older adults with depressive disorder: A population-based cohort study.","authors":"Diego Infante-Ventura, Benjamín Rodríguez-Díaz, Alejandra Abrante Luis, Cristina Valcárcel-Nazco, Miguel Ángel García Bello, Francisco Estupiñán-Romero, Francisco Javier Acosta Artiles, Beatriz González de León, Isabel Hurtado Navarro, Tasmania Del Pino-Sedeño","doi":"10.1016/j.inpsyc.2026.100189","DOIUrl":"10.1016/j.inpsyc.2026.100189","url":null,"abstract":"<p><strong>Aim: </strong>The objective is to study the prevalence of potentially inappropriate medications (PIMs) and analyze the relationship between PIM regimens and therapeutic adherence to antidepressant treatment in older adults diagnosed with depression within a Spanish population cohort.</p><p><strong>Methods: </strong>This retrospective, population-based cohort study used real-world data from older patients diagnosed with depression in the Canary Islands, Spain between 2013 and 2021. The prevalence of PIMs was determined using sets of criteria developed in the USA (Beers), Ireland (STOPP) and Germany (PRISCUS). Multivariate logistic regression models were performed to assess factors associated with PIM prescriptions and treatment adherence, including sociodemographic, clinical, and lifestyle variables RESULTS: Among the 12,272 patients over 65 years of age undergoing antidepressant treatment for late-life depression, the prevalence of PIM use ranged between 73 % and 89 %. A protective effect of increasing age and male sex was found. Patients with a higher number of psychiatric and nursing comorbidities showed a higher risk of receiving a PIM. A consistent trend was observed, the risk of non-adherence to treatment increases with the number of PIMs received.</p><p><strong>Conclusion: </strong>The findings here indicate a worrying prevalence of PIM prescription in this population. A higher risk of receiving a PIM was observed in comparatively younger older adults, women, and those with psychiatric or nursing comorbidities, with potential implications for treatment adherence. However, these results should be interpreted with caution. Further research is needed to clarify the relationship between adherence and PIM.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100189"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100012","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Worldwide changes in self-stigma among people with mental illness from 2005 to 2023: A cross-temporal meta-analysis and systematic review.","authors":"Xianying Lu, Huan Chen, Dingxi Bai, Xinyu Chen, Wenting Ji, Huiting Gao, Yijia Yuan, Chaoming Hou, Jing Gao","doi":"10.1016/j.inpsyc.2025.100106","DOIUrl":"10.1016/j.inpsyc.2025.100106","url":null,"abstract":"<p><strong>Background: </strong>Self-stigma in mental illness constitutes a growing public health imperative, with limited longitudinal data available to characterize its evolution over time. Here, we employed cross-temporal meta-analysis to systematically assess whether self-stigma levels have escalated, leveraging standardized measurement tools to quantify potential changes.</p><p><strong>Methods: </strong>We searched six databases (inception to July 2024) for studies measuring self-stigma using the Internalized Stigma of Mental Illness Inventory (ISMI). Two researchers independently screened studies and extracted data. SPSS 25.0 and R 4.4.2 were used for correlation, regression, and quantification of self-stigma differences.</p><p><strong>Results: </strong>179 articles involving 33,046 people were identified. Self-stigma levels increased across all ISMI dimensions from 2005 to 2023 (β = 0.086-0.283), corresponding to small-to-large effect size (d = 0.30-0.89). Notably, stigma resilience increased significantly (d = 0.89), which is a noteworthy observation, suggesting a positive shift in their ability to cope with stigmatizing experiences. Subgroup analyses further revealed that people with mild mental illnesses experienced more severe and frequent self-stigma (d = 1.07-2.80) than those with severe mental illnesses (d = 0.13-1.02). Geographically, self-stigma increased in Asian regions (d > 0), while trends in other regions were mixed (d > 0 or < 0). Importantly, statistically significant differences (P^a <0.05 in ISMI and its dimensions) across illness severities and continents mental illness located further validated these subgroup findings.</p><p><strong>Conclusions: </strong>Self-stigma within the studied age group has indeed increased from 2005 to 2023, underscoring an immediate need for intervention. Consequentially, continuous data is essential to monitor its persistence. Moreover, exploring self-stigma's social determinants to provide effective intervention strategies is necessary.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100106"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Changes in regional cerebral blood flow associated with psychosis in patients with Alzheimer's disease.","authors":"Baomin Zhao, Yidi Wang, Yu Wang, Chunxue Ji, Nan Zhang","doi":"10.1016/j.inpsyc.2026.100190","DOIUrl":"10.1016/j.inpsyc.2026.100190","url":null,"abstract":"<p><strong>Objective: </strong>To identify changes in regional cerebral blood flow (CBF) associated with psychosis in patients with Alzheimer's disease (AD) through arterial spin labeling (ASL) magnetic resonance imaging (MRI).</p><p><strong>Methods: </strong>Sixty patients with AD, whose diagnoses were supported by amyloid PET, were recruited. A set of neuropsychological tests was used to evaluate cognitive function and neuropsychiatric symptoms. All participants were assigned to either the AD with psychosis (AD-P) group or the AD without psychosis (AD-NP) group according to their hallucination and delusion scores on the Neuropsychiatric Inventory (NPI). Regional CBF was measured using pseudocontinuous ASL MRI in the resting state.</p><p><strong>Results: </strong>Compared with AD-NP patients, AD-P patients achieved lower scores on the Mini-Mental State Examination (MMSE) and on the cognitive domains of memory and visuospatial function; they also exhibited worse performance in terms of daily function. Compared with the AD-NP group, the AD-P group exhibited significantly lower global CBF. After the global values normalized, relatively lower CBFs were detected in the left middle temporal gyrus, right supramarginal gyrus and bilateral precuneus in patients with AD-P. Lower CBF in the precuneus was correlated with both cognitive impairment and hallucinations.</p><p><strong>Conclusion: </strong>Psychosis was associated with more severe cognitive impairment and lower CBF in regions of the temporal and parietal lobes, particularly the precuneus, in AD patients.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100190"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146112849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ageism, ableism, and their intersection: Evidence from the Longitudinal Ageing Study in India wave 1.","authors":"Sayani Das, Liat Ayalon","doi":"10.1016/j.inpsyc.2025.100104","DOIUrl":"10.1016/j.inpsyc.2025.100104","url":null,"abstract":"<p><strong>Objectives: </strong>Ageism and ableism significantly affect the well-being, social inclusion, and access to resources of older adults, often shaped by socio-cultural factors, yet remain underexplored within the heterogeneous context of India. This study examines the prevalence and associated factors of ageism, ableism, and their intersection among older adults in India.</p><p><strong>Design, setting, participants, & measurements: </strong>Utilizing data from the Longitudinal Aging Study in India (LASI) Wave 1, this study analyzed responses from 30,728 community-dwelling older adults (aged 60 +) across all states and union territories. Participants were categorized into four groups: ageism, ableism, intersection, or none, based on their everyday experiences of discrimination related to age, physical disability, or both. Multinomial logistic regression identified sociodemographic factors associated with these discriminations, with the cumulative advantage/disadvantage theory serving as conceptual framework.</p><p><strong>Results: </strong>The weighted prevalence of ageism was 10.3 %, ableism was 0.5 %, and 0.4 % reported both. Men were more likely to report ableism (AOR2.66) and intersectional discrimination (AOR2.03) but less likely to report ageism (AOR 0.89). Increasing age (AOR 1.24) and lower education (AOR1.48) were associated with ageism, while unemployment was linked to ableism (AOR2.07) and intersectional discrimination (AOR 2.21). Notably, participants in poorer health were more likely to report ageism (AOR 1.29), ableism (AOR 3.15), and intersectional discrimination (AOR 5.14) based on the Healthy Aging Index, compared to healthier participants.</p><p><strong>Conclusions: </strong>The findings highlight how different factors shape experiences of discrimination, underscoring the importance of adopting both individual and intersectional perspectives to effectively address these issues and design targeted interventions.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100104"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144336526","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and psychometric validation of the bullying experiences of the elderly scale in geriatric care.","authors":"Jong-Ni Lin, Hua-De Lin, Cheng-Chen Chou, Yi-Tzu Chen, Chi-Jane Wang","doi":"10.1016/j.inpsyc.2026.100238","DOIUrl":"10.1016/j.inpsyc.2026.100238","url":null,"abstract":"<p><strong>Background: </strong>Bullying is a common issue that undermines older adults' health and well-being yet often goes unnoticed. Despite its impact, assessment tools specifically designed to identify bullying against this population are limited.</p><p><strong>Objectives: </strong>This study aimed to develop the Bullying Experiences of the Elderly (BEE) scale and evaluate its psychometric properties among older adults.</p><p><strong>Methods: </strong>The BEE scale was theoretically grounded in Olweus's bullying framework, stereotype embodiment theory, and social-ecological theory. A three-phase cross-sectional design was used, including item generation based on theoretical foundations, refinement through content and face validity review, and evaluation of construct validity in a larger survey sample. A sample of 922 community-dwelling older adults was recruited from commonly frequented or residential locations in Taiwan. Recruitment was conducted through door-to-door visits and face-to-face interactions. Factor analysis was performed for data analysis.</p><p><strong>Results: </strong>The finalized BEE scale includes 18 items and a four-factor structure: ageism-related bullying, sexual bullying, dignity violation, and social bullying. The scale demonstrated strong content validity and good internal consistency, with Cronbach's α coefficients exceeding.80. The indices of confirmatory factor analysis supported the internal measurement structure of the four-factor model, with composite reliability values exceeding.60 and the square roots of the average variance extracted for each factor being greater than the inter-factor correlations.</p><p><strong>Conclusion: </strong>The BEE scale is a reliable instrument for assessing bullying experiences among older adults, offering valuable support for improving geriatric care. Its routine application may inform the development of targeted interventions; however, further research is required to validate the scale across different contexts.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100238"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148470537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Treatments for vascular depression in older adults: A systematic review.","authors":"Bernardo Flôr-Rodrigues, Sofiene Ben Aissa, David Miranda, Charline Compagne, Pierre Vandel, Armin von Gunten, Vasiliki Orgeta, Christoph Mueller, Kevin Swierkosz-Lenart, Beatriz Pozuelo Moyano","doi":"10.1016/j.inpsyc.2026.100249","DOIUrl":"10.1016/j.inpsyc.2026.100249","url":null,"abstract":"<p><strong>Background: </strong>Vascular depression (VaD) is a subtype of late-life depression (LLD) associated with cerebrovascular disease, cognitive impairment, and poor response to standard antidepressants. Despite its clinical relevance and association with increased risk of dementia, no specific treatment guidelines currently exist.</p><p><strong>Objectives: </strong>To systematically review randomised controlled trials (RCTs) on the clinical efficacy of pharmacological and non-pharmacological interventions for VaD in older adults.</p><p><strong>Methods: </strong>A systematic search of MEDLINE, EMBASE, Web of Science and ClinicalTrials.gov registry identified 7994 records, of which 8 RCTs met inclusion criteria. Studies included participants with late-life VaD. Interventions comprised pharmacological treatments (augmentation with tandospirone and nimodipine) and neuromodulation techniques (rTMS and tDCS). Outcomes included treatment response and remission, change in depressive symptoms, and other clinical outcomes.</p><p><strong>Results: </strong>Augmentation with tandospirone was associated with faster early symptom improvement in three of four trials. Nimodipine improved remission at 2 months and reduced recurrence in one of two trials. Neuromodulation interventions showed promising antidepressant effects and cognitive benefits (based on two trials). Treatments were generally well tolerated. However, study heterogeneity, small sample sizes, and short follow-up durations limited comparability and precluded meta-analysis. The overall certainty of evidence was low to very low.</p><p><strong>Conclusions: </strong>Evidence on treatment for VaD remains limited, highlighting the need for large, well-designed RCTs and integrated approaches combining vascular risk management with targeted therapies.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100249"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148697474","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Best practice implementation in gerontology and geriatrics delphi studies: a scoping review.","authors":"Shannon E Jarrott, Aaron M Ogletree, Shelbie G Turner, Michelle Demetres","doi":"10.1016/j.inpsyc.2026.100248","DOIUrl":"10.1016/j.inpsyc.2026.100248","url":null,"abstract":"<p><strong>Background and objectives: </strong>With Delphi panels in aging research proliferating, we conducted a scoping review to: (1) aggregate key practice recommendations; (2) document their use in aging research; and (3) use findings to recommend practices and their reporting for aging researchers in the form of a Delphi Quality Criteria Rating Form for Aging (DQ4A).</p><p><strong>Research design and methods: </strong>We conducted a scoping review of Delphi studies focused on aging published in peer-reviewed journals using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR). Searches were run in May 2025 in relevant databases. Titles, abstracts, and full-texts screening yielding a sample of 102 articles. Data were extracted and synthesized to feature study characteristics and Delphi methodological practices. Results informed creation of the DQ4A.</p><p><strong>Results: </strong>Adherence to methodological recommendations varied, highlighting the need for streamlined guidance. Common practices included specification of panelist selection criteria (95%), provision of the final product (93%), and substantiation of Delphi method use (78%). Least represented practices included targeting number of panelists based on anticipated attrition (11%), use of double blinding (14%), and panelist review of original and modified products (18%). Using the DQ4A, we demonstrate that 24% of all studies had average quality, 33% had higher-than-average quality, and 43% had lower-than-average quality.</p><p><strong>Discussion and implications: </strong>Findings highlight methodological gaps, indicating recommendations to improve the Delphi method in gerontology and geriatrics. Investigators can use the DQ4A to improve conduct and reporting of Delphi studies while ensuring that resultant products reflect diverse stakeholder needs.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100248"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148648714","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Excess mortality and life-years lost in older adults with schizophrenia-spectrum disorders: A 6-year follow-up case-control study.","authors":"Chris Chit Sze Fung, Calvin Pak Wing Cheng, Joe Kwun Nam Chan, Tommy Ho-Fung Chung, Allen Ting Chun Lee, Linda Chiu Wa Lam, Pak Chung Sham, Mei Cheung Wong, Lap Kei Chan, Adelina Sze Hang Tsoi, Yu Ching Wong, Ting Keung Poon, Man Chak Chan, Katrina Tung Yee Tse, Heather Wai Sum Liu, Anson Yan Sou Tang, Sing-Hang Cheung, Corine Sau Man Wong, Wing Chung Chang, Wai Chi Chan","doi":"10.1016/j.inpsyc.2026.100196","DOIUrl":"10.1016/j.inpsyc.2026.100196","url":null,"abstract":"<p><p>The prevalence of older adults with schizophrenia is growing, yet age-specific mortality estimates and quantifying metrics remain scarce, limiting evidence-based healthcare management. We followed 2665 older adults (≥65 years) with schizophrenia-spectrum disorder (SSD) and 18,298 matched comparison group utilising Hong Kong electronic health records from 2005 to 2011. We estimated the mortality hazard ratios with Cox regression and competing risk analyses. We also quantified the mortality risks with life-years lost (LYLs) metric for enhanced clinical interpretation. Compared to the comparison group, older adults with SSD had 4-fold elevated all-cause mortality (HR4.39, 95 %CI: 4.02-4.80) and had 5.28 excess LYLs (95 %CI: 4.77-5.87). Natural causes accounted for 5.53 life-years lost, while unnatural causes contributed minimally despite an 8-fold elevated hazard ratio. Natural causes account the majority of excess mortality in older SSD patients. Our findings highlight the importance of prioritising physical health monitoring alongside psychiatric management for this vulnerable population.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100196"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146194276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mild cognitive impairment: New directions in predictors, diagnosis and biomarkers.","authors":"Corinne E Fischer","doi":"10.1016/j.inpsyc.2026.100211","DOIUrl":"10.1016/j.inpsyc.2026.100211","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100211"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147771166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and validation of prediction model (VALOR-m) for all-cause mortality following very late-onset schizophrenia-like psychosis: A 23-year population-based study.","authors":"Chris Chit Sze Fung, Joe Kwun Nam Chan, Wai Chi Chan, Calvin Pak Wing Cheng, Wing Chung Chang","doi":"10.1016/j.inpsyc.2026.100244","DOIUrl":"10.1016/j.inpsyc.2026.100244","url":null,"abstract":"<p><strong>Objectives: </strong>Individuals with very late-onset schizophrenia-like psychosis (VLOSLP) experience a persistent mortality gap compared to the general population, yet no validated prognostic tools tailored to this growing population exist. We aimed to develop and validate a 3-year all-cause mortality prediction model (VALOR-m) for individuals with VLOSLP.</p><p><strong>Design: </strong>We developed VALOR-m with LASSO-penalised Cox regression. To evaluate temporal drift and geographic generalisability, we employed a two-stage approach: 1)temporal validation stratified by two time periods (period 1: 2002-2013; period 2: 2014-2024), and 2)temporal recalibration with internal-external cross-validation (IECV) stratified by seven catchment areas in period 2. Discrimination was assessed by time-dependent AUC and Harrell's c-statistic; calibration by calibration slope and observed-to-expected ratio (O/E ratio).</p><p><strong>Participants: </strong>Using a population-based electronic health record cohort from Hong Kong (2002-2024), we identified 33,594 older adults (aged≥60 years) with VLOSLP.</p><p><strong>Results: </strong>Of 33,594 individuals included (16,262[48·4%] male; mean age of onset 76·4 years), 11,272 (33·6%) died within 3 years. VALOR-m retained 11 predictors and demonstrated good discrimination (pooled time-dependent AUC:0·772 95%CI[0·765-0·779]; Harrell's c-statistic 0·734 95%CI[0·728-0·741]) and satisfactory calibration (calibration slope 0·885 95%CI[0·859-0·911]; O/E ratio 0·972 95%CI[0·908-1·041]) in IECV.</p><p><strong>Conclusions: </strong>VALOR-m provides the first validated individualised mortality risk estimates for individuals with VLOSLP, applicable to real-world clinical practice using routinely collected data. VALOR-m achieved comparable discrimination to conventional comorbidity indices with fewer predictors, suggesting that it better captures the unique mortality profile of VLOSLP, and supporting its use to guide antipsychotic treatment decisions, personalised healthcare management in this understudied yet growing population.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100244"},"PeriodicalIF":6.0,"publicationDate":"2026-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148578615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}