International psychogeriatrics最新文献

{"title":"More errors in Bachu A. K. et al. Electroconvulsive therapy in individuals with dementia/major NCD presenting with behavioral symptoms: A systematic review. International Psychogeriatrics (2024) 36:864-79 and (2025) 37:100084.","authors":"Per Bergsholm","doi":"10.1016/j.inpsyc.2025.100119","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100119","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100119"},"PeriodicalIF":4.6,"publicationDate":"2025-07-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144698513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond participation: Toward a contextualized understanding of creative arts and cognition.","authors":"Ke Meng, Maowei Chen","doi":"10.1016/j.inpsyc.2025.100112","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100112","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100112"},"PeriodicalIF":4.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Silent nights: Adjunctive lemborexant for managing nighttime agitation and sleep disturbances in Alzheimer's dementia.","authors":"Debanjan Banerjee","doi":"10.1016/j.inpsyc.2025.100122","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100122","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100122"},"PeriodicalIF":4.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring how family caregivers of people with Alzheimer's disease experience role captivity: A qualitative study.","authors":"Wenxia Zhang, Wenting Xu, Junzhi Duan, Junyu Tang, Qunli Zhu, Xifeng Pi, Jing Huang","doi":"10.1016/j.inpsyc.2025.100114","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100114","url":null,"abstract":"<p><strong>Background: </strong>Family caregivers of people with Alzheimer's disease often find their caregiving role intensely encompassing, which could lead to other areas of their experience being constrained or to \"role captivity.\" The impact of role captivity on family members warrants further exploration. This study aimed to investigate the experiences of role captivity among family caregivers of people with Alzheimer's disease and analyze the causes of role captivity.</p><p><strong>Methods: </strong>Semi-structured interviews with family caregivers of people with Alzheimer's disease in the neurology and geriatrics departments of a hospital in Hunan Province, China, were conducted from May 2024 to August 2024. The data were analyzed using a reflexive thematic analysis.</p><p><strong>Results: </strong>Fifteen family caregivers of people with Alzheimer's disease were interviewed. Three themes were identified: 1) complex and shifting emotional experiences; 2) social, work, and lifestyle changes within role captivity; and 3) role captivity formation shaped by caregiving responsibilities and family finances.</p><p><strong>Conclusion: </strong>Amongst family caregivers in our study, role captivity was a prominent concern. It can be manifested through internal emotional impact and external social, work, and life changes. The analysis found that lack of family support, too much caregiving responsibility falling on the family caregiver, and financial strain were significant contributors to role captivity. Suggestions were made for primary care having an important role in managing diseases and reducing disease burden.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100114"},"PeriodicalIF":4.6,"publicationDate":"2025-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144690146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Depression and apathy in older adults: Diagnostic relevance, clinical implications and challenges.","authors":"Florindo Stella, Orestes Forlenza","doi":"10.1016/j.inpsyc.2025.100121","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100121","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100121"},"PeriodicalIF":4.6,"publicationDate":"2025-07-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144667652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Senescence Associated Secretory Phenotype, a key marker of cellular senescence, is elevated in depression and moderated by sex.","authors":"Nishika Navrange, Ana Paula Mendes-Silva, Charles F Reynolds, Julie Wetherell, Benoit Mulsant, Mary C Kimmel, Eric J Lenze, Breno Satler Diniz","doi":"10.1016/j.inpsyc.2025.100113","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100113","url":null,"abstract":"<p><strong>Objective: </strong>Studies have found elevation in a key biomarker of aging (the senescence-associated secretory phenotype (SASP) index) in depression. We investigated whether sex moderates the association between the SASP and major depression in older adults.</p><p><strong>Methods: </strong>We included 423 older adults in a current major depressive episode and 140 adults with no history of depression. We measured the plasma levels of SASP biomarkers using multiplex immunoassays. The interaction effect between sex, depression diagnosis, and senescence markers were analyzed by general linear models, adjusted for confounding variables.</p><p><strong>Results: </strong>Individuals with depression had a higher SASP index than the healthy comparison group (t-test= -3.902, p < 0.001). We found a significant diagnosis by sex interaction (F= 9.112, df= 1540, p = 0.003), with males with depression having the highest SASP index levels (F=20.678, df=1540, p < 0.001).</p><p><strong>Conclusions: </strong>In older adults, sex plays a significant role in senescence-related changes in depression. A higher senescence burden in males with depression may be an indicator of greater vulnerability to accelerated biological aging and a marker of elevated risk of adverse outcomes in this sex.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100113"},"PeriodicalIF":4.6,"publicationDate":"2025-07-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144626229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Revisiting dementia findings in Nigeria's oldest old: A critical appraisal of long-term survivorship data.","authors":"Brijesh Sathian, Javed Iqbal, Israel Nascimento, Hanadi Al Hamad","doi":"10.1016/j.inpsyc.2025.100110","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100110","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100110"},"PeriodicalIF":4.6,"publicationDate":"2025-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144618079","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Important for preventing but also living well with cognitive impairment - The associations between social relationships, well-being, and cognition in very old adults.","authors":"Selina Vogel, Susanne Zank","doi":"10.1016/j.inpsyc.2025.100109","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100109","url":null,"abstract":"<p><strong>Objectives: </strong>Social relationships are well-researched as protective factors against cognitive impairment, but their role for individuals experiencing cognitive impairment is less clear. The present study examined the associations between cognitive impairment, social relationships, and well-being in very old adults (80 + years), a high-risk group for cognitive impairment.</p><p><strong>Design: </strong>Using representative data from the Study on Quality of Life and Well-Being in North-Rhine Westphalia (NRW80+ Study), we analyzed three social factors (close network, leisure activity, loneliness) and two well-being measures (depressiveness, positive affect) across very old individuals with and without cognitive impairment. We also investigated whether cognitive impairment affected the associations between social factors and well-being.</p><p><strong>Setting: </strong>Computer-assisted interviews were conducted with target persons or proxies in private housing and care facilities.</p><p><strong>Participants: </strong>The final sample included 1516 participants: 66.80 % without cognitive impairment, 15.00 % with mild impairment, and 18.20 % with major impairment.</p><p><strong>Measurements: </strong>Social and well-being measures were assessed through standardized interviews.</p><p><strong>Results: </strong>Cognitive impairment was associated with poorer social outcomes and lower well-being. Meanwhile, stronger social connections were linked to higher well-being. The associations were partially influenced by cognitive impairment. Notably, low leisure engagement was more strongly associated with increased depressiveness in individuals with major cognitive impairment than in those without (B = -0.53 [-0.83, -0.23], p < .001).</p><p><strong>Conclusions: </strong>Our findings emphasize the importance of social integration in preserving well-being for individuals with cognitive impairment. As the incidence of cognitive impairment rises, future research should not only focus on prevention but also on improving the situation for those affected.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100109"},"PeriodicalIF":4.6,"publicationDate":"2025-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144575477","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Worldwide changes in self-stigma among people with mental illness from 2005 to 2023: A cross-temporal meta-analysis and systematic review.","authors":"Xianying Lu, Huan Chen, Dingxi Bai, Xinyu Chen, Wenting Ji, Huiting Gao, Yijia Yuan, Chaoming Hou, Jing Gao","doi":"10.1016/j.inpsyc.2025.100106","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100106","url":null,"abstract":"<p><strong>Background: </strong>Self-stigma in mental illness constitutes a growing public health imperative, with limited longitudinal data available to characterize its evolution over time. Here, we employed cross-temporal meta-analysis to systematically assess whether self-stigma levels have escalated, leveraging standardized measurement tools to quantify potential changes.</p><p><strong>Methods: </strong>We searched six databases (inception to July 2024) for studies measuring self-stigma using the Internalized Stigma of Mental Illness Inventory (ISMI). Two researchers independently screened studies and extracted data. SPSS 25.0 and R 4.4.2 were used for correlation, regression, and quantification of self-stigma differences.</p><p><strong>Results: </strong>179 articles involving 33,046 people were identified. Self-stigma levels increased across all ISMI dimensions from 2005 to 2023 (β = 0.086-0.283), corresponding to small-to-large effect size (d = 0.30-0.89). Notably, stigma resilience increased significantly (d = 0.89), which is a noteworthy observation, suggesting a positive shift in their ability to cope with stigmatizing experiences. Subgroup analyses further revealed that people with mild mental illnesses experienced more severe and frequent self-stigma (d = 1.07-2.80) than those with severe mental illnesses (d = 0.13-1.02). Geographically, self-stigma increased in Asian regions (d > 0), while trends in other regions were mixed (d > 0 or < 0). Importantly, statistically significant differences (P^a <0.05 in ISMI and its dimensions) across illness severities and continents mental illness located further validated these subgroup findings.</p><p><strong>Conclusions: </strong>Self-stigma within the studied age group has indeed increased from 2005 to 2023, underscoring an immediate need for intervention. Consequentially, continuous data is essential to monitor its persistence. Moreover, exploring self-stigma's social determinants to provide effective intervention strategies is necessary.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100106"},"PeriodicalIF":4.6,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical trials for neuropsychiatric syndromes in major and mild neurocognitive disorders: A CONSORT-based approach.","authors":"Jeffrey L Cummings, Kate Zhong, Clive Ballard, Mary Sano, Jacobo Mintzer","doi":"10.1016/j.inpsyc.2025.100107","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100107","url":null,"abstract":"<p><p>Neuropsychiatric syndromes (NPS) such as agitation, psychosis, apathy, and irritability are among the most disabling features of major and mild neurocognitive disorders including Alzheimer's disease, other neurodegenerative disorders (NDD), and vascular cognitive impairment. Clinical trial methodologies for the treatment of these syndromes are evolving and the first agents to reduce NPS severity has been approved. Biomarkers are rapidly becoming available to guide clinical trial decision-making. Biomarkers can confirm the diagnosis of Alzheimer's disease and are playing a larger role in non-Alzheimer trials. The Consolidated Standards for Reporting Trials (CONSORT) specify the elements of clinical trials that must be reported when clinical trials are published. These criteria provide conventions for uniform reporting of all key aspects of a clinical trial and facilitate comparisons across trials. We describe best practices for clinical trials of NPS including research definitions of the NDD, use of biomarkers to support clinical diagnosis, research criteria for NPS, use of rating scales to define the severity of NPS at baseline and as endpoints for the clinical trial, and approaches to data analysis of specific interest in NPS trials. Standards for describing the limitations of trials and their generalizability are provided. The goal is to inform planning and reporting of NPS trials including the use of biomarkers based on CONSORT guidelines for best trial practices.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100107"},"PeriodicalIF":4.6,"publicationDate":"2025-06-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144496665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}