International psychogeriatrics最新文献

{"title":"Key modifiable factors in urban-rural differences in depression among older adults in China: A comparative study between China and the United States.","authors":"Juxiang Yang, Yi Wang, Xi Zheng, Hongchu Wang, Gang Song","doi":"10.1016/j.inpsyc.2025.100046","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100046","url":null,"abstract":"<p><strong>Objectives: </strong>Urban-rural differences in depression are evident among older adults in China but not in the United States. By comparing the two countries, this study aims to explore strategies for promoting regional equality in depression in China.</p><p><strong>Methods: </strong>Data from the China Health and Retirement Longitudinal Study (CHARLS) and the Health and Retirement Study (HRS) were utilized. Longitudinal data were used to describe urban-rural differences in depression prevalence among older adults in China (2011-2020) and the United States (2010-2020). Cross-sectional data from 2018 (CHARLS: 9840 participants; HRS: 10,381 participants) were used to identify key modifiable factors. A random forest algorithm was employed to determine the most important factors influencing depression, and comparisons between the two countries were made to identify modifiable factors. Multivariate logistic regression was used to analyze the relationship between these key modifiable factors and depression. A mediation model was applied to assess the mediating role of key modifiable factors in the relationship between residence and depression.</p><p><strong>Results: </strong>1) From 2011 to 2020, Urban-rural differences in depression prevalence among older adults were observed in China, but not in the United States. 2) In both China and the U.S., the top five factors ranked by importance were activities of daily living disability (ADLs), instrumental activities of daily living disability (IADLs), pain levels, self-reported health (SRH), and age. However, Urban-Rural Differences in ADLs, IADLs, and SRH were present in China but not in the United States. 3) ADLs, IADLs, and SRH collectively mediated 31.6 % (95 % CI: 0.268 - 0.360) of the relationship between residence and depression scores among older adults in China.</p><p><strong>Conclusion: </strong>Urban-rural differences in physical health status (ADLs, IADLs, and self-reported health) among older adults in China are associated with Urban-Rural Differences in depression. The absence of such inequalities in the U.S. may offer insights for developing policies to promote regional equality in depression among older adults in China.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100046"},"PeriodicalIF":4.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations of neurocognitive functioning with behavioral pathology in older adults.","authors":"Dilip V Jeste","doi":"10.1016/j.inpsyc.2025.100047","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100047","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100047"},"PeriodicalIF":4.6,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143407943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations between Attitudes to Aging with concurrent and twelve-year change in cognitive functioning in very old individuals.","authors":"Serena Sabatini, Katya Numbers, Nicole A Kochan, Perminder S Sachdev, Henry Brodaty","doi":"10.1016/j.inpsyc.2025.100045","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100045","url":null,"abstract":"<p><strong>Objectives: </strong>This study investigated the cross-sectional associations between participants' scores on five cognitive domains and global cognition and their scores on a multidimensional measure of self-perceptions of aging. This study also investigated whether 12-year change in the same cognitive domains and global cognition was associated with self-perceptions of aging.</p><p><strong>Design: </strong>Cross-sectional and longitudinal secondary analyses of a cohort study.</p><p><strong>Participants: </strong>Participants were 103 individuals (mean age at 12-year follow-up = 87.43 years; SD = 3.60; 60.2 % women) enrolled in the Sydney Memory and Aging Study (MAS) with 12-years of follow-up data.</p><p><strong>Measurements: </strong>Cognitive domains assessed over 7 waves were attention processing speed, language, executive function, visuospatial abilities, and memory. Self-perceptions of aging were assessed only at wave 7 using the three subscales of the Laidlaw' Attitudes to Aging Questionnaire: psychological growth, psychosocial loss, and (positive) physical change.</p><p><strong>Results: </strong>After having adjusted for age, sex, marital status, occupation when working, depressive symptoms, and numbers of physical health conditions and for multiple comparisons there were no significant cross-sectional associations between cognitive abilities and global cognition and the subscales of the Attitudes to Aging Questionnaire. After having adjusted for baseline cognition, age, sex, marital status, occupation when working, depressive symptoms, and numbers of physical health conditions there were no significant longitudinal associations between change in cognitive abilities and in general cognition and the subscales of the Attitudes to Aging Questionnaire.</p><p><strong>Conclusions: </strong>Cross-sectional and change scores on cognitive tasks and global cognition do not have an effect on Attitudes to Aging after having controlled for depressive symptoms.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100045"},"PeriodicalIF":4.6,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143399112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Harmonized Cognitive Assessment Protocol in the English Longitudinal Study of Ageing: Contrasting approaches to evaluation of factor structure.","authors":"Ying Liu, Shabina Hayat, Sarah Assaad, Dorina Cadar, Andrew Steptoe, Jinkook Lee, Alden L Gross","doi":"10.1016/j.inpsyc.2025.100042","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100042","url":null,"abstract":"<p><strong>Objectives: </strong>Cognitive theories and previous research on cognitive performance suggest a hierarchical pattern of interrelationships among cognitive tests, but the psychometric properties of the same tests may change when adapted for a different context or applied to a different population. We evaluated the factor structure of a cognitive battery of tests using an exploratory, data-driven approach and a confirmatory, theory-driven approach.</p><p><strong>Design: </strong>We estimated exploratory factor analyses (EFA) and confirmatory factor analysis (CFA). Agreement between the results based on the EFA and CFA approaches was evaluated by contrasting the identified domains and their corresponding items.</p><p><strong>Setting: </strong>Epidemiologic cohort study in England.</p><p><strong>Participants: </strong>Adults aged 65+ in the English Longitudinal Study of Ageing (ELSA).</p><p><strong>Measurements: </strong>Harmonized Cognitive Assessment Protocol battery of cognitive tests, adapted for the English context.</p><p><strong>Results: </strong>Both the EFA and CFA solutions yielded adequate model fit (RMSEA's < 0.05; CFI's > 0.92; SRMR's<0.06). However, only after multiple iterative steps, the EFA produced a factor structure that largely conformed to a priori theory of human cognitive abilities.</p><p><strong>Conclusions: </strong>This study provides an important cautionary tale for factor analytic approaches to evaluating domain structures when the tests available for factor analysis do not encompass a broad enough content of the construct: a factor solution is only as good as the bank of available items.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100042"},"PeriodicalIF":4.6,"publicationDate":"2025-02-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143364878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Indicative biomarkers of Lewy body disease as predictors of treatment resistance in late-onset depression.","authors":"Hitomi Matsui, Takehiro Tamura, Masashi Kameyama, Ko Furuta, Yuki Omori, Takashi Takeuchi, Hidehiko Takahashi, Genichi Sugihara","doi":"10.1016/j.inpsyc.2025.100043","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100043","url":null,"abstract":"<p><p>Late-onset depression (LOD) may indicate the prodromal phase of Lewy body disease (LBD) and is often associated with treatment resistance. However, the relationship between treatment resistance and indicative biomarkers of LBD is still unknown. This retrospective study investigated whether ¹²³I-ioflupane dopamine transporter single-photon emission computed tomography (DaT-SPECT) and ¹²³I-metaiodobenzylguanidine (MIBG) cardiac scintigraphy can predict treatment resistance in hospitalized patients with LOD. The study included 79 inpatients diagnosed with LOD between October 2018 and September 2023 at a geriatric psychiatry ward. DaT-SPECT and MIBG cardiac scintigraphy were used to assess dopaminergic and autonomic function, respectively. Treatment resistance was defined as an inadequate response to antidepressant monotherapy, where cases require electroconvulsive therapy (ECT) analyzed as a distinct group. Logistic regression showed that DaT-SPECT abnormalities significantly predicted nonresponse to antidepressant monotherapy (OR = 4.70, p = 0.013). While oral sensory hallucinations, another clinical marker linked to dopaminergic dysfunction, did not significantly predict treatment response, MIBG cardiac scintigraphy findings enhanced predictive accuracy for severe cases requiring ECT. Additionally, the Cochran-Armitage test indicated that the likelihood of nonresponse to antidepressant monotherapy and the need for ECT increased significantly with a higher number of abnormal LBD biomarkers (z = 7.37, p = 0.007; z = 10.91, p < 0.001, respectively). These results suggest that neurodegenerative processes in the prodromal phase of LBD may contribute to treatment resistance in LOD. The combination of DaT-SPECT and MIBG cardiac scintigraphy improves early identification of treatment resistance, supporting more timely and personalized interventions for hospitalized patients with LOD.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100043"},"PeriodicalIF":4.6,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074656","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnicity predicts long-term depressive symptom patterns in older adults with type 2 diabetes.","authors":"Yuxia Ouyang, David Manier, Ramit Ravona-Springer, Mery Mamistalov, Dar Gelblum, Anthony Heymann, Joseph Azuri, Laili Soleimani, Ruby Phillips, Mary Sano, Michal Schnaider Beeri, Elizabeth Guerrero-Berroa","doi":"10.1016/j.inpsyc.2025.100034","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2025.100034","url":null,"abstract":"<p><strong>Objectives: </strong>Depression is a chronic disorder that significantly affects functional decline in older adults, especially those with type 2 diabetes (T2D). Ethnic groups may experience different depression risks and severities, yet the effect of ethnicity on depression trajectories and specific dimensions in older adults with T2D remains largely unexamined. We examined the longitudinal associations of ethnicity with depression and its specific dimensions over time in older Ashkenazi and non-Ashkenazi Jews with T2D.</p><p><strong>Design: </strong>Generalized estimating equations (GEE) models were employed to analyze the longitudinal associations of ethnicity with numbers of depressive symptoms and specific depression dimension, adjusting for sociodemographics, cognition, T2D characteristics, and cardiovascular risk factors.</p><p><strong>Setting: </strong>Community-dwelling older adults from the longitudinal Israel Diabetes and Cognitive Decline (IDCD) study.</p><p><strong>Participants: </strong>902 Ashkenazi and non-Ashkenazi Jews, mean age= 72.3 years.</p><p><strong>Measurements: </strong>The Geriatric Depression Scale-15 (GDS-15) and its five dimensions: Dysphoric Mood, Withdrawal Apathy-Lack of Vigor, Anxiety, Hopelessness, and Memory Complaint.</p><p><strong>Results: </strong>At baseline, Ashkenazi Jews reported significantly lower GDS-15 scores compared to non-Ashkenazi Jews. They exhibited lower scores in Dysphoric Mood and Hopelessness dimensions. GEE models confirmed these findings, showing Ashkenazi Jews had significantly lower total GDS-15 scores (β = 0.86, 95 % CI 0.75-0.99; p = 0.03), Dysphoric Mood (β = 0.76 (0.52-0.90], p = 0.006), Hopelessness (β = 0.74 [0.58-0.95], p = 0.017) and lower rates of clinical depression (OR= 0.68 [0.52-0.90], p = 0.006). These data offered no evidence of a difference in trends between the Ashkenazi and non-Ashkenazi groups on depression trajectories.</p><p><strong>Conclusions: </strong>Ethnicity is associated with the longitudinal trajectories of depression and its specific dimensions in older adults with T2D. Further investigation of contributing factors, including social determinants of health, is essential.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100034"},"PeriodicalIF":4.6,"publicationDate":"2025-01-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143038853","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How social frailty is operationalized matters: Relationships with health and wellbeing in late adulthood.","authors":"Sarah P Coundouris, Sarah A Grainger, Daniel Schweitzer, Ruth E Hubbard, E-Liisa Laakso, Julie D Henry","doi":"10.1016/j.inpsyc.2024.100032","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2024.100032","url":null,"abstract":"<p><strong>Objectives: </strong>There are currently major inconsistencies in the methodological approaches used to index social frailty. The present study aimed to better understand which of these approaches may be most valuable in predicting older adult's physical health and psychological wellbeing.</p><p><strong>Design: </strong>One hundred and thirty-three participants aged 60-90 years completed five measures commonly used to index social frailty, along with five measures of physical health, and psychological wellbeing. Social frailty was not only assessed at the scale level but was also considered in terms of both the objectivity (versus subjectivity) of each scale item, and at the social concept level (whether each item captured lifestyle, living alone, loneliness, social activities, social network, social role, social support, or sociodemographic characteristics).</p><p><strong>Results: </strong>As predicted, subjective social frailty accounted for the largest share of explained variance of psychological wellbeing in older adults, relative to objective indicators and key demographics. However, contrary to hypotheses, objective social frailty failed to uniquely predict physical health. Further analyses revealed that the predictive value of subjective social frailty was driven primarily by feelings of loneliness.</p><p><strong>Conclusions: </strong>The present study provides novel insights into how operationalizations of social frailty vary in terms of their relationship with important indicators of real-life function. The findings have direct implications for the development of targeted interventions focused on reducing social frailty in late adulthood.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100032"},"PeriodicalIF":4.6,"publicationDate":"2025-01-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Daily-life walking speed, running duration and bedtime from wrist-worn sensors predict incident dementia: A watch walk - UK biobank study.","authors":"Lloyd L Y Chan, Maria Teresa Espinoza Cerda, Matthew A Brodie, Stephen R Lord, Morag E Taylor","doi":"10.1016/j.inpsyc.2024.100031","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2024.100031","url":null,"abstract":"<p><strong>Objective: </strong>To determine if wrist-worn sensor parameters can predict incident dementia in individuals aged 60 + years and to compare prediction with other tools.</p><p><strong>Design: </strong>Observational cohort study.</p><p><strong>Setting: </strong>Community PARTICIPANTS: The cohort comprised 47,371 participants without dementia, aged 60 + years, who participated in the UK Biobank study (mean age=67 ± 4 years; 52 % female).</p><p><strong>Measurements: </strong>Nineteen digital biomarkers were extracted from up-to-7-day wrist-worn sensor accelerometry data at baseline. Univariable and multivariable Cox proportional hazard models examined associations between sensor parameters and prospectively diagnosed dementia.</p><p><strong>Results: </strong>Median follow-up was 7.5 years (interquartile range: 7.0 to 9.0 years), during this time 387 participants (0.8 %) were diagnosed with dementia. Among the gait parameters, slower maximal walking speed had the strongest association with incident dementia (32 % decrease in hazard for each standard deviation increase) followed by lower daily step counts (30 % decrease) and increased step-time variability (17 % increase). While adjusting for age and sex, running duration, maximal walking speed and early bedtime were identified as independent and significant predictors of dementia. The multivariable prediction model performed comparably to the ANU-ADRI and UKB-Dementia Risk Score models in the UK Biobank cohort.</p><p><strong>Conclusions: </strong>The study findings indicate that remotely acquired parameters from wrist-worn sensors can predict incident dementia. Since wrist-worn sensors are highly acceptable for long-term use, wrist-worn sensor parameters have the potential to be incorporated into dementia screening programs.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100031"},"PeriodicalIF":4.6,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143005304","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can neuromodulation alleviate cognitive deficits?","authors":"Miklos Argyelan, Sohag Sanghani","doi":"10.1016/j.inpsyc.2024.100021","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2024.100021","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"37 1","pages":"100021"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382362","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sexuality among older adults or too old having sex: Can healthcare professionals challenge the existing taboo?","authors":"Katerina Beji Sedlackova, Lidmila Hamplova, Alzbeta Bartova, Iva Holmerova","doi":"10.1016/j.inpsyc.2024.100016","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2024.100016","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"37 1","pages":"100016"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}