International psychogeriatrics最新文献

{"title":"Neuropsychiatric symptoms in neurocognitive disorders (NPS-NCD): IPA roadmap for the next decade.","authors":"Anne Margriet Pot, May Sano, Jacobo Mintzer, Jeff Cummings, Dilip V Jeste","doi":"10.1016/j.inpsyc.2026.100290","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100290","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100290"},"PeriodicalIF":6.0,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149038798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Temporal pattern of dementia with Lewy bodies diagnostic labels around electroconvulsive therapy: A nationwide claims-based study\" [Int Psychogeriatr (2026) 100224].","authors":"Masahiro Hata, Yuki Miyazaki, Shun Takahashi, Manabu Ikeda","doi":"10.1016/j.inpsyc.2026.100287","DOIUrl":"10.1016/j.inpsyc.2026.100287","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100287"},"PeriodicalIF":6.0,"publicationDate":"2026-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149038793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Older adults with serious mental illness engagement in a smoking cessation program: A mixed-methods evaluation.","authors":"Heather Leutwyler, Katerina Melino, Erin Hubbard, Nadra Lisha","doi":"10.1016/j.inpsyc.2026.100284","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100284","url":null,"abstract":"<p><strong>Introduction: </strong>Older adults with serious mental illness (SMI) experience substantially reduced life expectancy, with tobacco use contributing significantly to premature mortality. Although many individuals with SMI express interest in quitting smoking, effective and engaging cessation interventions tailored to this population remain limited.</p><p><strong>Objective: </strong>To examine engagement in a group-based smoking cessation intervention among older adults with SMI and explore factors influencing engagement using a mixed-methods approach.</p><p><strong>Methods: </strong>We analyzed data from participants aged ≥ 50 years enrolled in a randomized controlled trial of a 12-week group-based smoking cessation intervention. Quantitative analyses assessed retention, smoking behavior, and readiness to quit. Linear mixed-effects models with random intercepts for participants were used to evaluate changes in outcomes over time. Qualitative data were collected through semi-structured interviews and analyzed using grounded theory methods.</p><p><strong>Results: </strong>Forty participants with SMI (mean age = 58.0 years, SD = 4.7) were included. Twenty-six participants (65%) completed the 6-week assessment and 22 (55%) completed the full 12-week intervention. Mixed-effects models revealed a significant effect of time on smoking behavior, with cigarettes smoked per week decreasing significantly from baseline to midpoint (B = -38.31, 95% CI [-58.71, -17.90], p < .001) and remaining significantly lower than baseline at the end of the intervention (B = -26.72, 95% CI [-49.01, -4.43], p = .014). Readiness to quit scores did not change significantly over the 12-week period. Nine participants completed qualitative interviews. Analysis identified three interrelated dimensions of engagement: readiness to quit, access to the program, and accountability. Participants emphasized the importance of program structure, peer support, and opportunities to learn and apply cessation strategies in supporting behavior change.</p><p><strong>Conclusions: </strong>Older adults with SMI demonstrated sustained engagement and significant reductions in smoking during a 12-week group-based cessation intervention. Engagement was facilitated by readiness, program accessibility, and accountability, suggesting that multifaceted interventions addressing both behavioral and contextual factors may improve smoking cessation outcomes in this high-risk population.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100284"},"PeriodicalIF":6.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149024707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Converging pathways to late-life depression: Systemic, vascular, neurostructural and psychosocial factors.","authors":"Orestes V Forlenza","doi":"10.1016/j.inpsyc.2026.100283","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100283","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100283"},"PeriodicalIF":6.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149061251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is wisdom a predictor of quality of life in people with experience of dementia?","authors":"Swapneel Mirani, Tessa Williams, Shi Tang, Briony Harden, Martin Orrell","doi":"10.1016/j.inpsyc.2026.100279","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100279","url":null,"abstract":"<p><strong>Background: </strong>Wisdom has been linked to greater well-being in older adults, but its relationship with quality of life in people with dementia remains unclear. This study investigated the relationship between wisdom and quality of life for people with dementia and other groups with dementia experience.</p><p><strong>Methods: </strong>This cross-sectional online survey was conducted via the Join Dementia Research (JDR) platform, United Kingdom, with 3144 adults registered on the platform. Wisdom was measured using the 12-item Three-Dimensional Wisdom Scale (3D-WS-12) and quality of life using the Control, Autonomy, Self-realization, and Pleasure scale (CASP-12). Demographic information and type of dementia experience were also recorded. Data were analyzed using correlations, t-tests, ANOVAs, and linear regressions.</p><p><strong>Results: </strong>Wisdom was positively associated with quality of life, with reflective wisdom showing the highest correlation. Being female and older were each associated with higher wisdom scores. Family carers scored significantly higher on the 3D-WS-12 than people with dementia, and affective wisdom was most strongly associated with type of experience of dementia (for example as a person with dementia or as a carer).</p><p><strong>Discussion: </strong>The link between wisdom and quality of life in people suggests the possibility of practical implications for interventions that promote self-awareness and perspective-taking in dementia care. Cognitive and physical challenges of dementia may hinder the expression of wisdom. Longitudinal research is needed to examine how wisdom and quality of life change across the progression of dementia.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100279"},"PeriodicalIF":6.0,"publicationDate":"2026-09-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149109502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Studies of interventions and strategies to enhance cognition in older adults.","authors":"Carmelle Peisah","doi":"10.1016/j.inpsyc.2026.100276","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100276","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100276"},"PeriodicalIF":6.0,"publicationDate":"2026-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008535","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A caution in interpreting reliable cognitive decline in older adults at risk for Alzheimer's disease.","authors":"Michael L Thomas","doi":"10.1016/j.inpsyc.2026.100272","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100272","url":null,"abstract":"<p><p>Repeated cognitive screening of functionally independent older adults may help identify decline before performance crosses conventional thresholds for cognitive impairment, but interpreting longitudinal change requires distinguishing true change from measurement error. The Reliable Change Index (RCI) is commonly used for this purpose. Conventional RCI methods based on classical test theory (CTT), however, typically assume that measurement error is constant across examinees, an assumption that may be particularly problematic for screening instruments such as the Mini-Mental State Examination (MMSE), which often show pronounced ceiling effects. We compared conventional CTT- and difference-score-based item response theory (IRT) RCIs in 1136 cognitively unimpaired older adults with elevated brain amyloid from the A4 clinical trial. The two approaches were strongly correlated overall (r = .83). However, among the 92 participants identified as showing reliable decline by at least one method, 44 (47.8%) received discordant classifications. Thus, substantial overall correspondence between CTT- and IRT-based RCIs can co-occur with meaningful disagreement about which individuals have experienced reliable cognitive decline. These findings highlight the importance of accounting for variation in measurement precision when interpreting longitudinal change on cognitive screening measures in older adults. They also provide an important cautionary note for clinicians who rely on repeated cognitive screening, as detection of reliable decline may be particularly challenging among individuals with relatively preserved cognition who may be in the earliest stages of cognitive deterioration.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100272"},"PeriodicalIF":6.0,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148989282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuropsychiatric symptoms as predictors of progression to Alzheimer's disease in mild cognitive impairment: A comparative meta-analysis of apathy, depression, and anxiety.","authors":"Yuying Sun, Yu Cao, Jinye Ma, Wenhan Li, Hao Li, Zhanfei Tan","doi":"10.1016/j.inpsyc.2026.100275","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100275","url":null,"abstract":"<p><strong>Background: </strong>Identifying mild cognitive impairment (MCI) patients at high risk for Alzheimer's disease (AD) is a priority. The independent prognostic utility of neuropsychiatric symptoms (NPS) remains debated.</p><p><strong>Methods: </strong>We systematically searched longitudinal cohort studies that evaluated the predictive role of baseline apathy, depression, and anxiety for progression from MCI to clinical AD dementia. Pooled hazard ratios (HRs) with 95% confidence intervals (CIs) were calculated using random-effects models with Hartung-Knapp adjustment.</p><p><strong>Results: </strong>Twenty-two studies (346,185 MCI patients) were included. Apathy demonstrated a statistically significant predictive association with progression (HR = 2.57, 95% CI: 1.58-4.17, p = 0.003). Depression was not significantly associated with progression overall (HR = 1.32, 95% CI: 0.69-2.50). In pre-specified subgroup analyses, a significant association was observed only among studies with follow-up ≥ 3 years (HR = 2.20, 95% CI: 1.08-4.46), although the test for subgroup differences did not reach conventional significance. Anxiety was not significantly associated with progression risk (HR = 1.27).</p><p><strong>Conclusion: </strong>Apathy is a robust and consistent behavioral predictor of progression from MCI to clinical AD dementia. Depression may represent a potential long-term risk pattern, whereas anxiety requires further validation. Domain-specific neuropsychiatric assessment may improve future risk stratification.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100275"},"PeriodicalIF":6.0,"publicationDate":"2026-09-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148982263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative analysis of striatal subregions in behavioral variant frontotemporal dementia and late-life schizophrenia: A multimodal MRI study.","authors":"Huizi Li, Xingyu Zhang, Mingyang Yao, Tao Li, Guoliang Pan, Huali Wang","doi":"10.1016/j.inpsyc.2026.100273","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100273","url":null,"abstract":"<p><strong>Objective: </strong>Behavioral variant frontotemporal dementia (bvFTD) and schizophrenia share similar clinical manifestations, cognitive profiles and overlapping brain lesions. The striatal subregions play critical roles in both disorders, yet relevant comparative investigations remain limited. This study aimed to explore the distinct neural mechanisms between bvFTD and late-life schizophrenia by comparing striatal subregional structure, function and spatial correlations of neurotransmitters.</p><p><strong>Methods: </strong>A total of 36 patients with bvFTD, 21 patients with late-life schizophrenia and 56 healthy comparison group were enrolled. All participants underwent neurocognitive assessment, behavioral evaluation and magnetic resonance imaging (MRI). Voxel-Based Morphometry and Resting-state functional connectivity (RSFC) analyses based on the Human Brainnetome Atlas. Partial correlation analysis was performed to evaluate the associations of imaging metrics with neuropsychological and behavioral measures. JuSpace was used to compare RSFC-neurotransmitter spatial correlation differences between bvFTD and schizophrenia groups.</p><p><strong>Results: </strong>A graded reduction in gray matter volume was observed across most striatal subregions: the bvFTD group showed the smallest volume, then the schizophrenia group. Both bvFTD and schizophrenia groups exhibited similar RSFC in the right nucleus accumbens and bilateral dorsolateral putamen. Specifically, the bvFTD group presented unique aberrant intra-striatal functional connectivity, including connections between the left nucleus accumbens and right putamen, as well as between the left dorsal caudate nucleus and left ventral caudate. Significant partial correlations were detected: Hamilton Depression Rating Scale scores negatively correlated with bilateral dorsal caudate volume in the schizophrenia group. Additionally, the bvFTD group exhibited lower spatial correlations between RSFC and the density maps of 5-HT₆, α4β2, M₁, mGluR5 and D₂ receptors, compared with the schizophrenia group.</p><p><strong>Conclusions: </strong>These findings suggest similar striatal impairment patterns but divergent underlying neural mechanisms in bvFTD and schizophrenia, offering new insights into the neural circuits of clinical phenotypes and the pathophysiological basis of the two disorders.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100273"},"PeriodicalIF":6.0,"publicationDate":"2026-09-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148929968","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative characteristics of mental health networks in older adults across care models: A cross-sectional study of community home-based and institutional care.","authors":"Beibei Chen, Yufeng Wang, Jing Hu, Wenbin Feng, Mengxuan Wu, Jie Wu","doi":"10.1016/j.inpsyc.2026.100269","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2026.100269","url":null,"abstract":"<p><strong>Background: </strong>Care models significantly impact older adults' mental health, yet the dynamic interplay among symptoms remains unclear. This study compared the integrated sleep-psychological-social support networks between older adults in community home-based and institutional care.</p><p><strong>Methods: </strong>We included 973 adults aged ≥ 60 years (home-based: n = 727; institutional: n = 246). Mental health networks were estimated using Gaussian Graphical Models. We evaluated node centrality, bridge expected influence, and assessed between-group differences using the Network Comparison Test (NCT) and stability analyses.</p><p><strong>Results: </strong>The home-based network was denser (density = 0.576), featuring subjective sleep quality as the core node, with anxiety and life satisfaction acting as key cross-domain bridges. Conversely, the institutional network was sparser (density = 0.348), with core nodes shifting toward objective indicators (e.g., sleep duration) and weakened bridging functions. NCT revealed no statistically significant between-group differences in global strength (p = 0.233) or overall structure (p = 0.124). The home-based network demonstrated good stability, whereas the institutional network's stability was limited by sample size.</p><p><strong>Conclusions: </strong>Mental health networks differ descriptively across care models. Home-based networks are driven by subjective experiences and show strong cross-domain integration, while institutional networks rely on objective indicators and exhibit modular separation. These findings highlight the need for personalized, context-specific psychological interventions targeting core symptoms in different care settings.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"100269"},"PeriodicalIF":6.0,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148912026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}