Maxwell Cooper, Leah Couzner, Jennifer Smith-Merry, Brian Draper, Lee-Fay Low, Monica Cations
{"title":"The role of dementia and mild cognitive impairment in deaths by suicide in Australia: A retrospective study of coronial records.","authors":"Maxwell Cooper, Leah Couzner, Jennifer Smith-Merry, Brian Draper, Lee-Fay Low, Monica Cations","doi":"10.1016/j.inpsyc.2024.100002","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2024.100002","url":null,"abstract":"<p><strong>Objective: </strong>To characterise the cohort of individuals who died by suicide in two Australian states where dementia or mild cognitive impairment was implicated in the death, and to examine the themes related to their deaths.</p><p><strong>Design: </strong>Retrospective multi-methods study.</p><p><strong>Setting: </strong>Coronial data, including police and autopsy reports, held in the National Coronial Information System.</p><p><strong>Participants: </strong>All individuals who died by suicide in South Australia and New South Wales between 2011 and 2020 where dementia or mild cognitive impairment was relevant to their death (n = 152).</p><p><strong>Measurements: </strong>Descriptive quantitative analysis of demographic and clinical data, and thematic analysis of themes in autopsy and police reports.</p><p><strong>Results: </strong>Included deaths were 67 people with confirmed dementia or MCI, 24 people with suspected dementia or MCI, 56 family members/friends of people with dementia or MCI, and 5 people who cited fear of dementia as a contributing factor for their death. The cohort were majority male (62.4 %), aged 74 years on average at the time of death (standard deviation 12.5 years), married (53.9 %), and retired (74.3 %). Themes described psychological distress and existential despair related to impairments, loss of autonomy and burdensomeness, fear of future degeneration and burdening others even where dementia onset had not occurred, factors external to but related to the dementia that cause distress and burden for family members and friends (e.g. housing, legal matters), and the phenomenon of simultaneous deaths.</p><p><strong>Conclusions: </strong>Mitigation of secondary effects of dementia, as well as fear and stigma, may prevent some death by suicide.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"37 1","pages":"100002"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Advancing the understanding of ECT in dementia: A critical examination of current evidence. A commentary on \"Electroconvulsive therapy in individuals with dementia presenting with behavioral symptoms: A systematic review\" by Bachu et al.","authors":"Manan J Shah","doi":"10.1016/j.inpsyc.2024.100026","DOIUrl":"https://doi.org/10.1016/j.inpsyc.2024.100026","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"37 1","pages":"100026"},"PeriodicalIF":4.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143382319","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are there sensitive age ranges at which disrupted sleep differentially affects cognition?","authors":"Kyler Mulhauser, Greta B Raglan","doi":"10.1017/S104161022400053X","DOIUrl":"10.1017/S104161022400053X","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"1086-1088"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141179573","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validation of the Japanese version of the Social Functioning in Dementia scale and COVID-19 pandemic's impact on social function in mild cognitive impairment and mild dementia.","authors":"Sumiyo Umeda, Hideki Kanemoto, Maki Suzuki, Tamiki Wada, Takashi Suehiro, Kyosuke Kakeda, Yoshitaka Nakatani, Yuto Satake, Maki Yamakawa, Fuyuki Koizumi, Daiki Taomoto, Sakura Hikida, Natsuho Hirakawa, Andrew Sommerlad, Gill Livingston, Mamoru Hashimoto, Kenji Yoshiyama, Manabu Ikeda","doi":"10.1017/S1041610224000401","DOIUrl":"10.1017/S1041610224000401","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to psychometrically evaluate and validate a Japanese version of the Social Functioning in Dementia scale (SF-DEM-J) and investigate changes in social function in people with dementia during the coronavirus disease-19 (COVID-19) pandemic.</p><p><strong>Design: </strong>We interviewed people with mild cognitive impairment (MCI) and mild dementia and their caregivers during June 2020-March 2021 to validate patient- and caregiver-rated SF-DEM-J and compared their scores at baseline (April 2020 to May 2020) and at 6-8 months (January 2021 to March 2021) during a time of tighter COVID-19 restrictions.</p><p><strong>Setting: </strong>The neuropsychology clinic in the Department of Psychiatry at Osaka University Hospital and outpatient clinic in the Department of Psychiatry and Neurology at Daini Osaka Police Hospital, Japan.</p><p><strong>Participants: </strong>103 dyads of patients and caregivers.</p><p><strong>Measurements: </strong>SF-DEM-J, Mini-Mental State Examination, Neuropsychiatric Inventory, UCLA Loneliness Scale, and Apathy Evaluation Scale.</p><p><strong>Results: </strong>The scale's interrater reliability was excellent and test-retest reliability was substantial. Content validity was confirmed for the caregiver-rated SF-DEM-J, and convergent validity was moderate. Caregiver-rated SF-DEM-J was associated with apathy, irritability, loneliness, and cognitive impairment. The total score of caregiver-rated SF-DEM-J and the score of Section 2, \"communication with others,\" significantly improved at 6-8 months of follow-up.</p><p><strong>Conclusions: </strong>The SF-DEM-J is acceptable as a measure of social function in MCI and mild dementia. Our results show that the social functioning of people with dementia, especially communicating with others, improved during the COVID-19 pandemic, probably as a result of adaptation to the restrictive life.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"1205-1218"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140093909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Elaine Stasiulis, Gary Naglie, Sarah Sanford, Patricia Belchior, Alexander Crizzle, Isabelle Gélinas, Barbara Mazer, Paige Moorhouse, Anita Myers, Michelle M Porter, Brenda Vrkljan, Mark J Rapoport
{"title":"Developing the Driving and Dementia Roadmap: a knowledge-to-action process.","authors":"Elaine Stasiulis, Gary Naglie, Sarah Sanford, Patricia Belchior, Alexander Crizzle, Isabelle Gélinas, Barbara Mazer, Paige Moorhouse, Anita Myers, Michelle M Porter, Brenda Vrkljan, Mark J Rapoport","doi":"10.1017/S1041610222001235","DOIUrl":"https://doi.org/10.1017/S1041610222001235","url":null,"abstract":"<p><strong>Objectives: </strong>Despite three decades of research, gaps remain in meeting the needs of people with dementia and their family/friend carers as they navigate the often-tumultuous process of driving cessation. This paper describes the process of using a knowledge-to-action (KTA) approach to develop an educational web-based resource (i.e. toolkit), called the Driving and Dementia Roadmap (DDR), aimed at addressing some of these gaps.</p><p><strong>Design: </strong>Aligned with the KTA framework, knowledge creation and action cycle activities informed the development of the DDR. These activities included systematic reviews; meta-synthesis of qualitative studies; interviews and focus groups with key stakeholders; development of a Driving and Dementia Intervention Framework (DD-IF); and a review and curation of publicly available resources and tools. An Advisory Group comprised of people with dementia and family carers provided ongoing feedback on the DDR's content and design.</p><p><strong>Results: </strong>The DDR is a multi-component online toolkit that contains separate portals for current and former drivers with dementia and their family/friend carers. Based on the DD-IF, various topics of driving cessation are presented to accommodate users' diverse stages and needs in their experiences of decision-making and transitioning to non-driving.</p><p><strong>Conclusion: </strong>Guided by the KTA framework that involved a systematic and iterative process of knowledge creation and translation, the resulting person-centered, individualized and flexible DDR can bring much-needed support to help people with dementia and their families maintain their mobility, community access, and social and emotional wellbeing during and post-driving cessation.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"36 12","pages":"1157-1170"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Are there sensitive age ranges at which disrupted sleep differentially affects cognition?","authors":"Kyler Mulhauser, Greta B Raglan","doi":"10.1017/S104161022400053X","DOIUrl":"https://doi.org/10.1017/S104161022400053X","url":null,"abstract":"","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"36 12","pages":"1086-1088"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074419","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Validation of the Japanese version of the Social Functioning in Dementia scale and COVID-19 pandemic's impact on social function in mild cognitive impairment and mild dementia.","authors":"Sumiyo Umeda, Hideki Kanemoto, Maki Suzuki, Tamiki Wada, Takashi Suehiro, Kyosuke Kakeda, Yoshitaka Nakatani, Yuto Satake, Maki Yamakawa, Fuyuki Koizumi, Daiki Taomoto, Sakura Hikida, Natsuho Hirakawa, Andrew Sommerlad, Gill Livingston, Mamoru Hashimoto, Kenji Yoshiyama, Manabu Ikeda","doi":"10.1017/S1041610224000401","DOIUrl":"https://doi.org/10.1017/S1041610224000401","url":null,"abstract":"<p><strong>Objectives: </strong>We aimed to psychometrically evaluate and validate a Japanese version of the Social Functioning in Dementia scale (SF-DEM-J) and investigate changes in social function in people with dementia during the coronavirus disease-19 (COVID-19) pandemic.</p><p><strong>Design: </strong>We interviewed people with mild cognitive impairment (MCI) and mild dementia and their caregivers during June 2020-March 2021 to validate patient- and caregiver-rated SF-DEM-J and compared their scores at baseline (April 2020 to May 2020) and at 6-8 months (January 2021 to March 2021) during a time of tighter COVID-19 restrictions.</p><p><strong>Setting: </strong>The neuropsychology clinic in the Department of Psychiatry at Osaka University Hospital and outpatient clinic in the Department of Psychiatry and Neurology at Daini Osaka Police Hospital, Japan.</p><p><strong>Participants: </strong>103 dyads of patients and caregivers.</p><p><strong>Measurements: </strong>SF-DEM-J, Mini-Mental State Examination, Neuropsychiatric Inventory, UCLA Loneliness Scale, and Apathy Evaluation Scale.</p><p><strong>Results: </strong>The scale's interrater reliability was excellent and test-retest reliability was substantial. Content validity was confirmed for the caregiver-rated SF-DEM-J, and convergent validity was moderate. Caregiver-rated SF-DEM-J was associated with apathy, irritability, loneliness, and cognitive impairment. The total score of caregiver-rated SF-DEM-J and the score of Section 2, \"communication with others,\" significantly improved at 6-8 months of follow-up.</p><p><strong>Conclusions: </strong>The SF-DEM-J is acceptable as a measure of social function in MCI and mild dementia. Our results show that the social functioning of people with dementia, especially communicating with others, improved during the COVID-19 pandemic, probably as a result of adaptation to the restrictive life.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":"36 12","pages":"1205-1218"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143074588","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Susmita Chandramouleeshwaran, Waqas U Khan, Fiona Inglis, Tarek K Rajji
{"title":"Impact of psychotropic medications on cognition among older adults: a systematic review.","authors":"Susmita Chandramouleeshwaran, Waqas U Khan, Fiona Inglis, Tarek K Rajji","doi":"10.1017/S1041610223000844","DOIUrl":"10.1017/S1041610223000844","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this systematic review is to examine the cognitive impact of psychotropic medications including benzodiazepines, antidepressants, mood stabilizers, antipsychotics, or a combination of these drugs on older adults.</p><p><strong>Design: </strong>Systematic review.</p><p><strong>Setting: </strong>We searched Medline, PsycINFO, and Embase through the Ovid platform, CINAHL through EBSCO, and Web of Science.</p><p><strong>Participants and interventions: </strong>Randomized control trials (RCTs) and cohort studies that used a validated scale to measure cognition with a follow-up period of at least six months were included.</p><p><strong>Measurement: </strong>The primary outcome of interest was cognitive change associated with psychotropic medication use.</p><p><strong>Results: </strong>A total of 7551 articles were identified from the primary electronic literature search across the five databases after eliminating duplicates. Based on full-text analysis, 27 articles (two RCTs, 25 cohorts) met the inclusion criteria. Of these, nine each examined the impact of benzodiazepines and antidepressants, five examined psychotropic combinations, three on antipsychotic drugs, and one on the effects of mood stabilizers.</p><p><strong>Conclusions: </strong>This is the first systematic review to examine the cognitive impact of multiple psychotropic drug classes in older adults over an extended follow-up period (six months or more) using robust sample sizes, drug-free control groups, and validated cognitive instruments. We found evidence to indicate cognitive decline with the cumulative use of benzodiazepines and the use of antidepressants, especially those with anticholinergic properties among older adults without cognitive impairment at baseline. Further, the use of antipsychotics and psychotropic combinations is also associated with cognitive decline in older adults.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"1110-1127"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49677397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Philip D Harvey, Courtney Dowell-Esquivel, Justin E Macchiarelli, Alejandro Martinez, Peter Kallestrup, Sara J Czaja
{"title":"Early prediction of mastery of a computerized functional skills training program in participants with mild cognitive impairment.","authors":"Philip D Harvey, Courtney Dowell-Esquivel, Justin E Macchiarelli, Alejandro Martinez, Peter Kallestrup, Sara J Czaja","doi":"10.1017/S1041610224000115","DOIUrl":"10.1017/S1041610224000115","url":null,"abstract":"<p><strong>Background: </strong>Cognition in MCI has responded poorly to pharmacological interventions, leading to use of computerized training. Combining computerized cognitive training (CCT) and functional skills training software (FUNSAT) produced improvements in 6 functional skills in MCI, with effect sizes >0.75. However, 4% of HC and 35% of MCI participants failed to master all 6 tasks. We address early identification of characteristics that identify participants who do not graduate, to improve later interventions.</p><p><strong>Methods: </strong>NC participants (<i>n</i> = 72) received FUNSAT and MCI (<i>n</i> = 92) participants received FUNSAT alone or combined FUNSAT and CCT on a fully remote basis. Participants trained twice a week for up to 12 weeks. Participants \"graduated\" each task when they made one or fewer errors on all 3-6 subtasks per task. Tasks were no longer trained after graduation.</p><p><strong>Results: </strong>Between-group comparisons of graduation status on baseline completion time and errors found that failure to graduate was associated with more baseline errors on all tasks but no longer completion times. A discriminant analysis found that errors on the first task (Ticket purchase) uniquely separated the groups, <i>F</i> = 41.40, <i>p</i> < .001, correctly classifying 94% of graduators. An ROC analysis found an AUC of .83. MOCA scores did not increase classification accuracy.</p><p><strong>Conclusions: </strong>More baseline errors, but not completion times, predicted failure to master all FUNSAT tasks. Accuracy of identification of eventual mastery was exceptional. Detection of risk to fail to master training tasks is possible in the first 15 minutes of the baseline assessment. This information can guide future enhancements of computerized training.</p>","PeriodicalId":14368,"journal":{"name":"International psychogeriatrics","volume":" ","pages":"1182-1193"},"PeriodicalIF":4.6,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139912591","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}