International Journal of Rheumatic Diseases最新文献

{"title":"Immunoglobulin G4-Related Disease Presenting With Peripheral Neuropathy, Membranous Nephropathy and Interstitial Lung Disease: A Case Report","authors":"Tianhang Yu,&nbsp;Qiao Ye,&nbsp;Fang Luo","doi":"10.1111/1756-185X.70133","DOIUrl":"https://doi.org/10.1111/1756-185X.70133","url":null,"abstract":"<div>\u0000 \u0000 <p>Immunoglobulin G4-related disease (IgG4-RD) is a chronic, progressive inflammatory disease with fibrosis that affects multiple organs, while symptomatic peripheral nerve invasion is very rare. Here we present a Chinese male aged 77 years with peripheral neuropathy, membranous nephropathy, and interstitial lung disease diagnosed with IgG4-RD. The patient exhibited elevated levels of IgG4 and IgG4/IgG ratios in the blood. A chest computed tomography (CT) showed interstitial pneumonia in both lungs and multiple mediastinal lymphadenopathy. Additionally, electromyography shows neurogenic lesions in both lower extremities and axonal lesions involving motor nerves. Biopsies of the kidney showed membranous nephropathy with numerous IgG4-positive plasma cells. Patients treated with cyclophosphamide and high-dose methylprednisolone showed improvement in neuropathy, proteinuria, and interpulmonary severity. This case demonstrates the unusual presentation of IgG4-RD where peripheral neuropathy is the main feature with multisystem involvement but without mass lesions. It underscores the varied clinical manifestations of this disease.</p>\u0000 </div>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438767","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Series: Extracutaneous Findings of Eosinophilic Fasciitis Patients","authors":"Tuba Yuce Inel,&nbsp;Murat Karabacak,&nbsp;Fatos Onen,&nbsp;Merih Birlik","doi":"10.1111/1756-185X.70142","DOIUrl":"https://doi.org/10.1111/1756-185X.70142","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Eosinophilic fasciitis (EF) is a connective tissue disorder characterized by cutaneous changes similar to scleroderma, usually associated with peripheral eosinophilia. This case series highlights clinical findings, particularly extracutaneous involvement, in EF patients to enhance clinician awareness of this rare condition.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>EF patients' skin and visceral organ involvement, musculoskeletal findings, laboratory tests (including acute phase reactants, autoantibodies, protein electrophoresis, etc.), magnetic resonance imaging (MRI), skin biopsy results, and treatments were evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The patient's age at presentation was 54 (range 23–68), and 50% were female. All patients presented with skin thickening in the distal upper extremities, except for the hands and feet. Notably, 50% of the patients showed involvement in the trunk, while 87.5% exhibited involvement in the distal lower extremities. A total of 87.5% of patients had increased acute-phase reactants, and three-quarters had peripheral eosinophilia. Some patients presented with extracutaneous manifestations such as nonspecific pulmonary nodules, neuropathy, or arthritis. MRI scans on all patients revealed notable thickening, contrast enhancement, and increased signal intensity within the fascia. Treatment involved the initiation of corticosteroids, with 87.5% of patients requiring the addition of an immunosuppressive agent due to an inadequate response. While no hematological malignancies were detected during the follow-up period, solid cancer was detected in one patient.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Patients diagnosed with EF should undergo a thorough evaluation for extracutaneous involvement, including joints, lungs, and muscles, as well as screening for occult malignancies. In instances where the condition does not respond to steroid therapy, it may be necessary to consider additional immunosuppressive treatments.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143438769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic Potential of Janus Kinase Inhibitors in Juvenile Idiopathic Arthritis","authors":"Yi-Xuan Li,&nbsp;Chen Dong,&nbsp;Brian Shiian Chen,&nbsp;An-Ping Huo","doi":"10.1111/1756-185X.70134","DOIUrl":"https://doi.org/10.1111/1756-185X.70134","url":null,"abstract":"<p>Juvenile idiopathic arthritis (JIA) is a heterogeneous group of rheumatic diseases characterized by chronic joint inflammation that begins before the age of 16 [<span>1</span>]. The term “JIA” encompasses seven distinct subtypes, each with unique clinical features, treatment approaches, and prognoses [<span>2</span>]. Current guidelines for managing JIA include a stepwise approach involving nonsteroidal anti-inflammatory drugs (NSAIDs), non-biologic disease-modifying antirheumatic drugs (DMARDs), and biologic DMARDs (bDMARDs). Biologic treatments include interleukin-1 (IL-1) inhibitors, interleukin-6 (IL-6) inhibitors, tumor necrosis factor (TNF) inhibitors, T-cell inhibitors, and anti-B cell therapies. Glucocorticoids (GCs) are often used as adjunctive therapy.</p><p>Despite significant advances in treating JIA over the past two decades, several challenges remain. Long-term use of corticosteroids and NSAIDs can lead to hepatic and renal toxicity, and IL-1 inhibitors may be associated with inflammatory liver infiltrates, particularly in systemic JIA (sJIA) patients [<span>3-5</span>]. Complications such as uveitis and macrophage activation syndrome (MAS) further complicate treatment, increasing the complexity of disease management [<span>6, 7</span>]. These challenges highlight the need for new therapeutic options, including Janus kinase (JAK) inhibitors, to improve outcomes for patients with JIA. Recent advances have introduced JAK inhibitors as a promising therapeutic option [<span>8</span>], particularly for patients with refractory JIA who do not respond to bDMARDs [<span>9</span>]. JAK inhibitors act by targeting the JAK–STAT signaling pathway, which is crucial in the pathogenesis of autoimmune diseases. This editorial explores the current evidence regarding using JAK inhibitors in JIA, emphasizing their efficacy and safety profiles.</p><p>JAK inhibitors are a promising therapeutic option for children with refractory JIA, particularly those with complications like MAS and uveitis. Early clinical trials and observational studies indicate they reduce disease activity, improve outcomes, and act as corticosteroid-sparing agents. However, the long-term safety and optimal dosing strategies require further investigation. As ongoing trials provide more data, JAK inhibitors could become a cornerstone for treating difficult-to-treat JIA.</p><p>Y.X.L., C.D., and B.S.C. write the draft paper. Y.X.L., C.D., and B.S.C. collect the references. Y.X.L., A.P.H., conceived this article. A.P.H. corrected and finalized the draft paper to the final version.</p><p>The authors declare no conflicts of interest.</p>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1756-185X.70134","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Factors Associated With Hallux Valgus Progression in Patients With Rheumatoid Arthritis: Insights From Non-Weight-Bearing Radiographs in the KURAMA Cohort","authors":"Tatsuhito Ikezaki,&nbsp;Koichi Murata,&nbsp;Takayuki Fujii,&nbsp;Akira Onishi,&nbsp;Kosaku Murakami,&nbsp;Masao Tanaka,&nbsp;Akio Morinobu,&nbsp;Shuichi Matsuda","doi":"10.1111/1756-185X.70131","DOIUrl":"https://doi.org/10.1111/1756-185X.70131","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>This longitudinal study investigated the factors associated with hallux valgus (HV) progression in patients with rheumatoid arthritis (RA).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We included 316 patients with RA who underwent foot radiography in 2015 and more than four years later. The HV angle (HVA), first-second intermetatarsal angle (IMA), first-fifth intermetatarsal angle (M1/M5 angle), and calcaneal pitch (CP) angle were measured. Sesamoid position on a non-weight-bearing radiograph was divided into seven grades with reference to the Hardy classification. Factors of HV progression were examined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>During a mean follow-up period of 6.1 years, HVA increased significantly. According to the grade of the sesamoid position, feet classified as grade VI or VII showed a greater change in HVA than those classified as below grade V. In feet below grade V, high disease activity, M1/M5 angle and right side were associated with the yearly increase &gt; 1° in the HVA. For grades VI and VII, a large CP angle was correlated with greater annual changes in the HVA.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Sesamoid position relates with the increase in HVA in patients with RA. Disease activity, the existence of splay foot, and the right side are significant risk factors for an HVA increase in grades I to V.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploration and Identification of Potential Biomarkers and Immune Cell Infiltration Analysis in Synovial Tissue of Rheumatoid Arthritis","authors":"Yan Liu,&nbsp;Huifang Hu,&nbsp;Tao Chen,&nbsp;Chenxi Zhu,&nbsp;Rui Sun,&nbsp;Jiayi Xu,&nbsp;Yi Liu,&nbsp;Lunzhi Dai,&nbsp;Yi Zhao","doi":"10.1111/1756-185X.70137","DOIUrl":"https://doi.org/10.1111/1756-185X.70137","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Rheumatoid arthritis (RA) is a prevalent autoimmune disease with synovial inflammation and hyperplasia, which can potentially cause degradation of articular cartilage, ultimately causing joint deformity, and impaired function. However, exact mechanisms underlying RA remain incompletely understood. This study seeks to uncover genomic signatures and potential biomarkers of RA, along with exploring the biological processes involved.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Six microarray datasets from RA patients, osteoarthritis (OA) and healthy controls (HC) of synovial tissue were obtained from the Gene Expression Omnibus (GEO) database for integrated analysis. Differentially expressed genes (DEGs) between groups were identified by “limma” package. The gene ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were carried out. Protein–protein interaction (PPI) network was analyzed by STRING and presented by Cytoscape. Weighted gene co-expression network analysis (WGCNA) was conducted to discover and construct the co-expression gene modules correlated with clinical phenotype. CytoHubba and MCODE were utilized for screening hub genes. Additionally, immune cell infiltration analysis was conducted utilizing CIBERSORT algorithm. The correlation of hub genes with immune cells were examined through Pearson Correlation Analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The overlapped 92 up-regulated genes were determined between RA versus normal controls and RA versus OA, which were primarily enriched in immune response, lymphocyte activation, and chemokine signaling pathway. By integrating WGCNA, Cytohubba and MCODE algorithms, 16 hub genes were identified including <i>CXCL13</i>, <i>ITK</i>, <i>CXCL9</i>, <i>CCR5</i>, <i>CCR7</i>, <i>NKG7</i>, <i>CCR7</i>, and <i>CD52</i>. We validated the diagnostic significance of these markers in RA by qRT-PCR. Moreover, the analysis of immune cell infiltration demonstrated a positive association between these hub genes with B cell naïve, plasma cell, T cells follicular helper, and macrophages M1. The abundance of these cells was markedly greater in RA compared to OA and normal controls.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This research ultimately identified 5 potential diagnostic biomarkers of RA in the synovial tissue, namely <i>NKG7</i>, <i>CD52</i>, <i>ITK</i>, <i>CXCL9</i>, and <i>GZMA</i>. These findings have enhanced our comprehension of RA pathogenesis and identified promising diagnostic and therapeutic targets of RA.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Case Report: A Diagnostic Challenge in Adult-Onset Hypophosphatasia With Persistent Polyarthralgia","authors":"Ryuichi Kanabuchi,&nbsp;Yu Mori,&nbsp;Hiroshi Hatakeyama,&nbsp;Mishio Chiba,&nbsp;Naoko Mori,&nbsp;Toshimi Aizawa","doi":"10.1111/1756-185X.70136","DOIUrl":"https://doi.org/10.1111/1756-185X.70136","url":null,"abstract":"","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"ADA2 Levels in Anti-MDA-5-Positive Idiopathic Inflammatory Myopathies in the MyoCite Cohort","authors":"Lekshmi Minikumari Rahulan,&nbsp;Anamika Kumari Anuja,&nbsp;Vikas Agarwal,&nbsp;Latika Gupta","doi":"10.1111/1756-185X.15438","DOIUrl":"https://doi.org/10.1111/1756-185X.15438","url":null,"abstract":"","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Of Mice and Men: Gout and Exercise","authors":"Naomi Schlesinger,&nbsp;Micah Drummond,&nbsp;Ali Abdul-Sater","doi":"10.1111/1756-185X.70135","DOIUrl":"https://doi.org/10.1111/1756-185X.70135","url":null,"abstract":"<p>The World Health Organization (WHO) reported in 2009 that a lack of exercise or a sedentary lifestyle was the fourth leading risk factor for mortality, accounting for an estimated 6% of all deaths worldwide [<span>1</span>]. The integrative care guidelines for rheumatoid arthritis strongly recommend exercise over no exercise, but the exercise type, frequency, intensity, and duration were not formally defined because the evidence on exercise interventions is limited [<span>2</span>].</p><p>Gout is the most common inflammatory arthritis worldwide, but despite the potential benefits of exercise for gout patients, research remains limited. The 2021 EULAR recommendations regarding lifestyle behaviors suggest that people with rheumatic diseases should perform aerobic and strengthening exercises [<span>3</span>]. The 2020 American College of Rheumatology (ACR) guidelines for managing gout do not include recommendations regarding exercise [<span>4</span>]. On the contrary, despite scarce evidence, rheumatologists recommend resting the involved joints during flares [<span>5</span>]. Our paper briefly overviews exercise and comorbidities associated with gout and highlights the scientific evidence underpinning what is known about exercise in gout patients.</p><p>All authors were involved in drafting or revising the article critically for important intellectual content, and all authors approved the final version for publication.</p><p>N.S.: Advisor or Review Panel Member: Olatec, AMGEN, SOBI, Protalix, Shanton, Arthrosi, Scilex; M.D.: scientific advisor for Immunis.</p><p>The authors declare no conflicts of interest.</p>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1756-185X.70135","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Bidirectional Mendelian Randomization Study of Tea-Drinking Habits and Risk of Elevated Serum Uric Acid Levels","authors":"Weitian Yan,&nbsp;Xingqiang Wang,&nbsp;Zining Peng,&nbsp;Qian Deng,&nbsp;Mengyuan Zhu,&nbsp;Fanyu Meng,&nbsp;Weiqing Zhao,&nbsp;Weijian Zhou,&nbsp;Nian Liu,&nbsp;Jingjin Wu,&nbsp;Jiangyun Peng","doi":"10.1111/1756-185X.70128","DOIUrl":"https://doi.org/10.1111/1756-185X.70128","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>Although recent animal experiments have revealed that tea intake improves elevated serum uric acid (SUA) levels, a causal link between the consumption of different types of tea and SUA levels remains undetermined.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Bidirectional Mendelian randomization (MR) analysis based on genome-wide association studies was used to assess the causal relationship between consumption of different types of tea and the risk of elevated SUA levels in European and Asian populations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Forward MR analysis showed that tea intake was significantly associated with lower SUA levels (<i>p</i> = 0.0013). The estimated effect value (<span></span><math>\u0000 <semantics>\u0000 <mrow>\u0000 <mi>β</mi>\u0000 </mrow>\u0000 <annotation>$$ beta $$</annotation>\u0000 </semantics></math> <span></span><math>\u0000 <semantics>\u0000 <mrow>\u0000 <mo>=</mo>\u0000 </mrow>\u0000 <annotation>$$ = $$</annotation>\u0000 </semantics></math> −0.0440) suggests that for every 1-unit increase in tea intake, there is a 0.044-unit decrease in SUA levels. However, there is no reverse causality between SUA and tea intake (<i>p</i> = 0.2824). No causal relationship was found between the consumption of different types of tea and risk of elevated SUA levels (<i>p</i> &gt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Although this bidirectional MR study provided evidence of a causal relationship between tea intake and SUA levels, however, due to limitations associated with the sample size and strength of instrumental variables, a definite conclusion was not possible.</p>\u0000 </section>\u0000 </div>","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1111/1756-185X.70128","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143423694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of Emerging New Autoimmune Diseases After COVID-19 Vaccination: Correspondence","authors":"Hinpetch Daungsupawong,&nbsp;Viroj Wiwanitkit","doi":"10.1111/1756-185X.70095","DOIUrl":"https://doi.org/10.1111/1756-185X.70095","url":null,"abstract":"","PeriodicalId":14330,"journal":{"name":"International Journal of Rheumatic Diseases","volume":"28 2","pages":""},"PeriodicalIF":2.4,"publicationDate":"2025-02-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143396921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}