International Microbiology最新文献

{"title":"Isolation and characterization of multi-drug-resistant Microbacterium esteraromaticum bacteriophage: assessment of antibacterial efficacy and genomic insights.","authors":"Shenwei Cheng, Hao Wang, Keqiang Zhang, Fuyuan Liu, Xingliang Gao, Lianzhu Du","doi":"10.1007/s10123-025-00703-1","DOIUrl":"https://doi.org/10.1007/s10123-025-00703-1","url":null,"abstract":"<p><p>Microbacterium esteraromaticum, a common bacterium utilized in the degradation of organic pollutants, is prevalently found in the wastewater environments of rural areas. However, the excessive use of antibiotics in recent years has endowed M. esteraromaticum with a broad spectrum of antibiotic resistance, transforming it into a potential high-risk contaminant capable of disseminating antibiotic resistance genes (ARGs) within the environment. Lytic bacteriophages, due to their characteristic ability to lysogenize and specifically target host bacteria, have emerged as potent biocontrol agents. In this study, a specific bacteriophage, CASP3, targeting the multi-drug resistant M. esteraromaticum (MDR-ME), was isolated from a wastewater treatment facility. The assessment of phage CASP3 revealed several noteworthy characteristics, including good tolerance and a targeted effect against multidrug-resistant MDR-ME. Studies observed that CASP3, to some extent, reduced the ARGs carried by its host. Furthermore, it demonstrated good environmental compatibility, with no significant potential risks identified. The successful isolation of CASP3 not only provides a new addition to phage resources targeting this bacterium but also offers a potential biocontrol tool for mitigating ARG dissemination and reducing public health risks in rural areas.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Screening and identification of beneficial soil bacteria: evaluating inoculation effects on plant growth with and without organic matter.","authors":"Shokufeh Moradi, Mohammad Reza Sarikhani","doi":"10.1007/s10123-025-00704-0","DOIUrl":"https://doi.org/10.1007/s10123-025-00704-0","url":null,"abstract":"<p><p>Plant growth-promoting bacteria (PGPB) play a vital role in enhancing crop productivity by improving nutrient availability, phytohormone production, and stress tolerance. While the individual effects of PGPB and organic matter on plant growth are well-documented, their combined influence remains less explored. This research aimed to investigate the effects of certain plant growth-promoting bacteria belonging to different genera on the growth of Corn when organic matter was added to the soil. Plant growth-promoting properties were measured using conventional methods, and the highest phosphate solubility (42.46 mg/L) and auxin production (3.36 mg/L) were observed in isolate Bacillus 2MDP-10, while the highest release of potassium was measured in isolate Azotobacter 3MDP-4 (6.73 mg/L). A greenhouse experiment was conducted using a factorial, completely randomized design. Results indicated that all measured growth parameters, including fresh and dry weight of roots and shoots, plant height, stem diameter, and chlorophyll index, were significantly higher in inoculated treatments compared to the non-inoculated treatment (negative control). Ensifer sp. 3MDP-1 improved Corn growth more effectively than the positive control. This isolate resulted in a 2.8-fold increase in shoot dry weight, a 2.4-fold increase in root dry weight, a 29% increase in plant height, and a 2.4-fold increase in chlorophyll index relative to the negative control. Our results demonstrated that the addition of organic matter in the form of manure significantly enhanced all measured parameters; however, no significant interaction was observed between manure addition and bacterial inoculation, except for root dry weight and nitrogen percentage. It is likely that bacterial colonization in the rhizosphere and the utilization of carbon released by the roots are key factors responsible for this response.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Altered cell length in deletion mutants of the different divIVA genes in Rhodococcus erythropolis PR4.","authors":"Shabnam Parwin, Preeti Srivastava","doi":"10.1007/s10123-025-00702-2","DOIUrl":"https://doi.org/10.1007/s10123-025-00702-2","url":null,"abstract":"<p><p>Unlike other Actinobacteria, Rhodococcus erythropolis PR4 contains three different copies of divIVA genes. The three divIVA genes show about 22-38% similarity with each other. Deletion mutants of the divIVA genes resulted in altered morphology: elongated cells in △divIVA-2 and short rod-shaped cells in △divIVA-1 and △divIVA-3. The expression of the divIVA-2 gene was found to be higher as compared to the divIVA-1 and divIVA-3 genes in wild-type cells. The subcellular localisation studies revealed that the three different DivIVA proteins are spatially present at different regions of cell space. Our results suggest that an interplay of the three DivIVA proteins plays a role in cell shape maintenance in R. erythropolis PR4. Bioinformatics analysis and interactome study show that amongst the three copies of divIVA genes, the second copy, i.e., divIVA-2 gene, might have a more governing function in the cell division process as compared to the other two copies.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144799061","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microbial community variation enhances active compound composition in Salvia miltiorrhiza.","authors":"Zhi Lin Chen, Hong Zhi Du, Jian Ke Wang, Chang Lin, Shan Shan Liang, Wei Wei Ze, Chong Xin Yue, Ting Ting Feng, Wei Li","doi":"10.1007/s10123-025-00700-4","DOIUrl":"https://doi.org/10.1007/s10123-025-00700-4","url":null,"abstract":"<p><p>Salvia miltiorrhiza is a widely used medicinal plant, and post-harvest processing methods such as sweating may influence its metabolite composition and microbial interactions. However, the metabolic and microbial changes induced by sweating remain poorly understood. This study aimed to investigate how sweating affects the metabolite profile of S. miltiorrhiza and its associated bacterial communities, with a focus on identifying key metabolic shifts and microbial dynamics. Widely targeted metabolomics was employed to compare the composition and relative content of metabolites between control (non-sweated) and sweated S. miltiorrhiza plants. Additionally, high-throughput sequencing was used to analyze variations in bacterial communities at different sweating stages. A total of 435 differentially present metabolites were identified, categorized into 11 classes, with quinones, phenolic acids, and lipids being the most prominent. Sweating significantly increased microbial diversity and richness, and we established a correlation between the accumulation of quinones and phenolic acids and shifts in bacterial community structure. Notably, sweating enhanced the levels of key metabolites, which in turn promoted the relative abundance of potentially beneficial microorganisms. Furthermore, distinct bacterial populations at different sweating stages contributed to the unique quality traits of S. miltiorrhiza. The findings demonstrate that sweating not only alters the metabolite profile of S. miltiorrhiza but also shapes its associated bacterial communities, leading to improved accumulation of bioactive compounds.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144794379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential susceptibility of Streptococcus dentisani to dental surfaces: An atomic force microscopy study.","authors":"Brianda Karina Félix-Sicairos, Rita Elizabeth Martínez Martínez, Eleazar Samuel Kolosovas-Machuca, Jaime Ruiz-García, Alex Mira, José Luis Cuellar Camacho, Saray Aranda Romo","doi":"10.1007/s10123-025-00696-x","DOIUrl":"https://doi.org/10.1007/s10123-025-00696-x","url":null,"abstract":"<p><strong>Background: </strong>Given frequent dental restorations, understanding the interactions of probiotic Streptococcus dentisani with enamel and dental materials is key, in contrast to the well-studied Streptococcus mutans. This knowledge is vital for the potential applications in promoting oral health of S. dentisani.</p><p><strong>Objective: </strong>This study aims to evaluate and compare S. mutans and S. dentisani initial adhesion, proliferation, and colonization on dental enamel and commonly used dental materials: nickel-chromium alloy, porcelain, lithium disilicate, autocured, and thermocured acrylics, using atomic force microscopy (AFM).</p><p><strong>Methods: </strong>The study utilized S. mutans ATCC 35665 and S. dentisani CECT 7746 cultured in brain-heart infusion (BHI) broth. The dental substrates used consisted of enamel obtained from healthy unerupted third molars, nickel-chromium alloy (Ni-Cr), porcelain, lithium disilicate, and both autocured and thermocured acrylics. All simples were cut into 1 cm pieces and subsequently mounted for the AFM analysis. Bacterial suspensions were incubated on these surfaces for 24 h. Surface topography and bacterial adhesion, proliferation, and colonization were analyzed using AFM in contact mode. Roughness parameters (R_a, R_rms, R_Max) were quantified from AFM images using the Nanoscope analysis software.</p><p><strong>Results: </strong>Atomic force microscopy analysis revealed that after a 24-h incubation, S. mutans demonstrated a superior capacity to adhere, proliferate, and colonize all tested substrates compared to S. dentisani. Streptococcus dentisani was found to be more susceptible to the bactericidal effects of the materials. Notably, porcelain and lithium disilicate surfaces exhibited strong antimicrobial activity. On porcelain, no intact S. dentisani cells were observed, only bacterial debris. Similarly, lithium disilicate showed evidence of bacterial decomposition for both strains, suggesting a potent bactericidal effect.</p><p><strong>Conclusion: </strong>For the first time, our data revealed that S. dentisani exhibited a reduced capacity for dental surface adhesion, proliferation, and colonization across all tested substrates, compared to S. mutans.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":""},"PeriodicalIF":2.3,"publicationDate":"2025-08-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144784287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Production of ectoine by Vreelandella boliviensis using non-aseptic repeated-batch and continuous cultivations in an air-lift bioreactor.","authors":"Jeanett Daga-Quisbert, Daniela Mendieta, Gunaratna Kuttuva Rajarao, Antonius J A van Maris, Jorge Quillaguamán","doi":"10.1007/s10123-024-00626-3","DOIUrl":"10.1007/s10123-024-00626-3","url":null,"abstract":"<p><p>Ectoine, an osmolyte produced by various microorganisms, has numerous commercial applications. Vreelandella boliviensis (formerly called Halomonas boliviensis) generates high ectoine concentrations, i.e., 78.6 g/L. This study investigated three cultivation strategies for ectoine production in a non-aseptic air-lift bioreactor. The first strategy was performed in a repeated-batch mode with 5% (w/v) NaCl to induce cell growth, followed by the addition of solid NaCl to a final concentration of 12.5% (w/v) to prompt ectoine production. A maximum dry cell weight of 13.8 g/L at 46.5 h, a maximum ectoine concentration of 1.37 g/L at 37.5 h, and a maximum volumetric productivity of 0.93 g/L/d at 34.5 h were reached. The second strategy employed a three-step repeated-batch cultivation method. In the first step, cells were grown at the optimum salt concentration, harvested by centrifugation, and cultivated in a replenished medium for the second step. In the third step, the cells were harvested again and grown in a fresh medium containing 12.5% (w/v) NaCl. This strategy improved dry cell weight to 32 g/L, ectoine concentration to 4.37 g/L, and productivity to 1.76 g/L/day at 60 h of cultivation. The third strategy consisted of continuous cultivations that were investigated using different NaCl concentrations. The highest ectoine concentration of 2.83 g/L and productivity of 3.49 g/L/d were obtained with 8.5% (w/v) NaCl at a dilution rate of 0.05 (1/h). This study is the first to report ectoine production by V. boliviensis in continuous air-lift bioreactors under non-aseptic conditions.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":"1385-1394"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142893696","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Community composition and co-occurrence of free-living and particle-attached bacteria in the source region of the Ganges and Brahmaputra Rivers.","authors":"Namita Paudel Adhikari, Subash Adhikari, Komal Raj Rijal","doi":"10.1007/s10123-024-00607-6","DOIUrl":"10.1007/s10123-024-00607-6","url":null,"abstract":"<p><p>Bacteria have two trophic lifestyles in aquatic ecosystems, i.e., free-living (FL) and particle-attached (PA), with different but essential ecological roles. However, relevant knowledge is still dearth in the upstream source region of the Himalayan Rivers. Thus, we emphasized a comparative study on community composition, co-occurrence, and geographic distribution of the FL and PA bacteria and the effect of environmental factors in the source region of the Ganges and Brahmaputra Rivers. PA bacteria relative to FL harbored a significantly higher local diversity, richness, and evenness. A significantly higher abundance of Betaproteobacteria, Verrucomicrobiota, and Planctomycetota in PA trophic lifestyle and Gammaproteobacteria and Actinomycetota in FL tropic lifestyle and indicator OTUs belonging to related taxa were observed. The spatial variation of the FL and PA bacterial communities was most significantly impacted by dispersal limitation as a discrete factor. Among the environmental parameters, the total nitrogen (TN) was found to be a significant (P < 0.001) driver of the variation in PA communities. Meanwhile, particulate organic carbon (POC) and TN considerably explained the variation of FL communities. A significant correlation (P < 0.001) of TN with dominant bacterial taxa (Pseudomonadota, Actinomycetota, and Verrucomicrobiota) and FL and PA indicator OTUs associated with these taxa further confirmed nitrogen as the limiting nutrient in the source region of the Ganges and Brahmaputra Rivers. The co-occurrence network topological characteristics showed that the PA network was more stable than the FL network, which was more complicated and unstable. Thus, it can be speculated that FL communities relative to PA are more vulnerable to shifting upon disturbances.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":"1135-1148"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142465462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolation and characterization of bacteriophages targeting methicillin-resistant Staphylococcus aureus (MRSA) from burn patients and sewage water: a genomic and proteomic study.","authors":"Nishat Zafar, Muhammad Aamir Aslam, Sajjad Ur Rahman, Muhammad Saqib","doi":"10.1007/s10123-024-00618-3","DOIUrl":"10.1007/s10123-024-00618-3","url":null,"abstract":"<p><p>The spectrum of infections caused by methicillin-resistant Staphylococcus aureus (MRSA) ranges from minor conditions to potentially life-threatening diseases. The rising antibiotic resistance in MRSA often leads to treatment failures, underscoring the urgent need for novel eradication strategies. This study focuses on isolating MRSA from burn patients, determining its antibiogram profile, and isolating and characterizing bacteriophages from sewage water that target MRSA, alongside conducting genomic analysis of the phages. A total of 70 samples were collected from burn patients, with MRSA identification and characterization performed using a combination of biochemical and molecular techniques, as well as antibiotic sensitivity testing. Based on host range analysis, a specific phage (phage-3) was selected for detailed characterization, including proteomic analysis, genetic mapping, phylogenetic studies, and analysis of open reading frames (ORFs) and motifs. The prevalence of MRSA in the samples was found to be 28.6%. Antibiotic susceptibility tests indicated that 94% of the MRSA isolates were sensitive to tobramycin and gentamicin, while vancomycin exhibited the lowest sensitivity, with only 2% effectiveness. Using the soft agar overlay method, three bacteriophages (phage-1, phage-2, and phage-3) were successfully isolated from sewage water. Among these, phage-3 exhibited the broadest host range. Further analysis showed that phage-3 demonstrated optimal activity at pH levels between 6 and 8, and within a temperature range of 20-40 °C. Phage-3 also displayed a rapid adsorption phase within the first 0-5 min, and its one-step growth curve revealed a latent period lasting up to 30 min, followed by a significant increase in titer from 30 to 50 min. Proteomic analysis of phage-3 identified the presence of 33 kDa and 65 kDa proteins. Phylogenetic analysis showed that phage-3 shares 96.6% similarity with Mammallicoccus phage vB_MscM-PMS3. The ORF analysis identified 80 potential ORFs within the phage's entire genome.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":"1331-1347"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142785668","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of calf separation on gut microbiome and fecal metabolome of mother in the captive Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis).","authors":"Syed Ata Ur Rahman Shah, Bin Tang, Dekui He, Yujiang Hao, Maaz Ahmad, Ghulam Nabi, Richard McLaughlin, Chaoqun Wang, Zhangbing Kou, Kexiong Wang","doi":"10.1007/s10123-024-00613-8","DOIUrl":"10.1007/s10123-024-00613-8","url":null,"abstract":"<p><p>Social separation, or the absence of social support, can cause physical and psychological health issues. Social separation is crucial for the welfare of the Yangtze finless porpoise (YFP) in captivity because they face many challenges like frequent social separation, noise from visitors, and animal replacement, which can cause psychological and physiological stress. This research is aimed at assessing the potential negative impacts of social separation on the gut microbiome and metabolome of captive YFP, focusing on the potential imbalances caused by mother-calf separation. The study found that social separation did not alter the alpha and beta diversity of the gut microbes but increased the abundance of disease-associated taxa such as Romboutsia, Terrisporobacter, and Clostridium_sensu_stricto_13 in the MC (mother-calf) group while increasing Paeniclostridium and Clostridium_sensu_stricto_1 associated with host health in the MS (mother-separated) group. The fecal metabolome underwent significant changes during social separation, with stress-associated metabolites like kainic acid, phenethylamine glucuronide, and paxilline upregulated in the MC group and host health-associated metabolites like butyric acid, 6-hydroxyhexanoic acid, and fosinopril downregulated in the MS group. In addition, there was a strong association between the fecal microbiome and the metabolome of captive YFPs. The study enhances our comprehension of the detrimental effects of social separation, which result in disruptions in the gut microbiome and fecal metabolome. The study is aimed at introducing a new method for assessing the health and welfare of endangered mammals in captivity.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":"1197-1209"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142620141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Multifunctional metabolites of Streptomyces kunmingensis BS19 from bamboo rhizosphere soil.","authors":"Murthy Sangeetha, Sivakumar Sasirekha, Jaganathan Mahendran, Anbalmani Sivarajan, Manikkam Radhakrishnan, Kaari Manigundan, Syed G Dastager, Singaravel Sengottuvelu, Ramasamy Balagurunathan","doi":"10.1007/s10123-024-00619-2","DOIUrl":"10.1007/s10123-024-00619-2","url":null,"abstract":"<p><p>A pigmented bioactive molecule from Streptomyces kunmingensis BS19 was isolated, characterized, and evaluated for anti-infective, antiproliferative, and wound-healing properties. The yellow-red pigment produced from the strain BS19 showed promising activity against methicillin-resistant Staphylococcus aureus (MRSA) and Mycobacterium tuberculosis. Extracellular bioactive pigment from the strain BS19 was produced by agar surface fermentation and purified through bioassay guided preparative HPLC-based purification. Based on the results of UV, FT-IR, GC-MS, ¹H NMR, and ¹³C NMR spectral analyses, the purified pigment was identified as a chromopeptide class of molecule with phenoxazinone chromophore. Its molecular weight was determined as the chemical formula C₆₄H₉₀N₁₂O₁₆ and molecular weight 1283 g/mol. It exhibited promising antimicrobial activity against Staphylococcus aureus (ATCC 1720) and antiproliferative activity against 14 types of human cancer cell lines. It showed good in vivo wound-healing activity in the rat model. The present study explored Streptomyces kunmingensis as a newly added source for the isolation of chromopeptide antibiotics for antimicrobial, wound-healing, and anticancer applications.</p>","PeriodicalId":14318,"journal":{"name":"International Microbiology","volume":" ","pages":"1269-1282"},"PeriodicalIF":2.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142750874","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}