International journal of ophthalmology最新文献

{"title":"Artificial intelligence in ophthalmic optical coherence tomography angiography: a bibliometric analysis.","authors":"Si-Yuan Zhu, Qing Zhang, Wei-Hua Yang, Wei Chi","doi":"10.18240/ijo.2026.10.19","DOIUrl":"10.18240/ijo.2026.10.19","url":null,"abstract":"<p><strong>Aim: </strong>To analyze research landscapes, hotspots, and trends in artificial intelligence (AI) applied to ophthalmic optical coherence tomography angiography (OCTA) from 2015 to 2024, aiming to reveal global collaborations and guide future research.</p><p><strong>Methods: </strong>We retrieved publications from Web of Science Core Collection using AI and OCTA-related search terms. After screening, 237 articles were analyzed with CiteSpace (version 6.3.R1) for co-citation, collaboration, and keyword burst analysis.</p><p><strong>Results: </strong>Annual publications grew rapidly since 2017. China (94 publications) and the US (86 publications) were the most productive and influential countries. Research focused on: deep learning algorithms and vessel segmentation, ocular disease diagnosis including diabetic retinopathy and glaucoma, and automated vascular quantification and multimodal imaging. Key limitations included small sample sizes and limited algorithm generalizability.</p><p><strong>Conclusion: </strong>The integration of AI with OCTA has significantly advanced the automation and precise quantitative analysis of ophthalmic vascular imaging, demonstrating substantial potential for diagnosing various retinal and choroidal diseases. Future efforts should focus on developing more robust and interpretable AI models, conducting large-scale, multi-center clinical validation, and establishing standardized imaging and analysis protocols to ultimately realize the widespread adoption of AI-OCTA technology in routine clinical practice.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"2031-2040"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586959/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Suitability for lacrimal duct research: anatomical and histological evidence favors the rabbit model over the rat.","authors":"Shun-Guo Ma, Yuan Zhang, Hui-Yang Ai, Tian-Yu Zhou, Jing-Min Guo, Rong Liu","doi":"10.18240/ijo.2026.10.04","DOIUrl":"10.18240/ijo.2026.10.04","url":null,"abstract":"<p><strong>Aim: </strong>To investigate the histological and anatomical characteristics of the lacrimal duct system (LDS) in rabbits and rats and compare with that in humans to establish a suitable animal for LDS studies.</p><p><strong>Methods: </strong>New Zealand white rabbits (1.8-2 kg) and SD rats (250-300 g) were selected. Following tests were executed on their LDS, including anatomical measurements; computed tomographic dacryocystography; hematoxylin and eosin, Masson's trichrome, Periodic Acid-Schiff staining, and scanning electron microscope.</p><p><strong>Results: </strong>Although there were anatomical similarities between the rats and humans in LDS, the size of LDS was too small and the epithelial types differed from that of humans in LDS. The rabbit only had a lower lacrimal punctum and a lacrimal canaliculus, while they had the same types of lacrimal epithelium as human's and the size was suitable for clinical probing and intubation.</p><p><strong>Conclusion: </strong>Histologically, the lacrimal canaliculi of both rabbits and rats resemble those of humans, making both species applicable for biological studies targeting the lacrimal canaliculi. Nevertheless, the epithelial types of the lacrimal sac and nasolacrimal duct in rats differ significantly from humans, whereas those in rabbits are consistent with humans. Therefore, rabbits are more appropriate for biological research involving the nasolacrimal duct and lacrimal sac.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"1906-1913"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of high-intensity light on early lens-induced myopia in chicks: optical coherence tomography assessment.","authors":"Luo-Li Zhang, Yang-Yi Huang, Yu-Liang Wang, Xiao-Liao Peng, Tian Han, Xing-Tao Zhou","doi":"10.18240/ijo.2026.10.03","DOIUrl":"10.18240/ijo.2026.10.03","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the impact of high-intensity light on ocular length and structural thickness in chick model of the early lens-induced myopia (LIM) by optical coherence tomography (OCT).</p><p><strong>Methods: </strong>Four-day-old chicks were monocularly covered with -10 D lenses for a period of 2d, exposed to either high-intensity light (HL, 10 000 lx) or normal-intensity light (NL, 500 lx) for 12h per day. A two-dimensional visualized swept-source OCT system was used to measure anterior chamber depth (ACD), lens thickness, vitreous chamber depth, axial length, retinal thickness and choroidal thickness. The refractive error was measured with retinoscopy.</p><p><strong>Results: </strong>After 2d of treatment, the LIM eyes under NL condition experienced a greater myopic shift (<i>P</i>=0.028) and greater axial elongation (<i>P</i>=0.033) than those exposed to HL. ACD significantly increased in LIM eyes under NL condition when compared with baseline, while no statistical difference of ACD was found between day 2 and day 0 in LIM eyes under HL condition. LIM eyes all experienced the thinning of retinal thickness and choroidal thickness (all <i>P</i><0.05), with no statistically significant differences between NL and HL group.</p><p><strong>Conclusion: </strong>HL could reduce the development of LIM at an early stage. Under NL, hyperopic defocus appears to induce a deepening of ACD at the early stage; this effect could potentially be mitigated by HL. At an early stage, HL may have no significant effects on the changes in retinal and choroidal thickness in LIM eyes.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"1898-1905"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149007887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Traumatic isolated medial rectus muscle rupture associated with an anatomic insertional variation: a case report.","authors":"So-Jin Kim, Donny W Suh, Donghun Lee","doi":"10.18240/ijo.2026.10.25","DOIUrl":"10.18240/ijo.2026.10.25","url":null,"abstract":"","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"2087-2090"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586929/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008292","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Visual and refractive evaluation of two diffractive trifocal intraocular lens platforms with distant and near dominant light energy distributions.","authors":"Hyeck-Soo Son, So Hyun Yu, Kyungmin Koh, Gerd U Auffarth, Grzegorz Łabuz","doi":"10.18240/ijo.2026.10.11","DOIUrl":"10.18240/ijo.2026.10.11","url":null,"abstract":"<p><strong>Aim: </strong>To compare the visual, refractive, and optical performance of two diffractive trifocal intraocular lenses (IOLs) with analogous designs but different light distribution profiles.</p><p><strong>Methods: </strong>A total of 54 eyes from 48 patients undergoing cataract surgery received either the Gemetric™ (GM; Hoya Surgical Optics, Singapore) or the Gemetric™ Plus (GMP; Hoya Surgical Optics) IOLs. Preoperative demographics were comparable between the two groups. Generalized estimating equations (GEE) were utilized for statistical analysis to adjust for inter-eye correlations.</p><p><strong>Results: </strong>A total of 48 patients (54 eyes) were included in the analysis, of which 30 patients (33 eyes) received the GM IOL and 18 patients (21 eyes) the GMP IOL. The mean age was 59.6±6.1y (range: 48-72) in the GM group and 61.6±5.8y (range: 49-69) in the GMP group (<i>P</i>=0.339). At 3mo postoperatively, there were no statistically significant differences in uncorrected distance visual acuity (VA) and uncorrected near vision at 40 cm. However, the GM group showed statistically significantly better outcomes in corrected distance VA (<i>P</i>=0.003) and uncorrected intermediate VA at 66 cm (<i>P</i>=0.033). Conversely, uncorrected near VA at 33 cm was significantly superior in the GMP group (<i>P</i>=0.048). The objective assessment of optical quality showed improved distance and intermediate performance with the GM, while the GMP performed better at near, consistent with the patients' measured visual outcomes.</p><p><strong>Conclusion: </strong>Adjusting light distribution in otherwise identical trifocal IOLs results in distinct clinical and optical advantages, allowing surgeons to tailor IOL selection to patients' specific visual demands.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"1971-1977"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586934/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008298","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical intervention versus conservative management in optic disc pit maculopathy.","authors":"Zoé Dobbels, Matteo Mario Carlà, Nesrine Bokri, Sophie Bonnin, Raphaël Lejoyeux, Aude Couturier","doi":"10.18240/ijo.2026.10.17","DOIUrl":"10.18240/ijo.2026.10.17","url":null,"abstract":"<p><strong>Aim: </strong>To assess the functional and anatomical outcomes in patients with maculopathy related to an optic disc pit (ODP-M), managed with or without surgery.</p><p><strong>Methods: </strong>This retrospective monocentric study, included 52 patients (52 eyes) with ODP-M. Of these, 52% (<i>n</i>=27) were managed conservatively, while 48% (<i>n</i>=25) underwent surgery. Primary outcomes included changes in best-corrected visual acuity (BCVA) and anatomical parameters [central macular thickness (CMT), sub-foveal choroidal thickness (SFCT)], as well as the rate of fluid resolution.</p><p><strong>Results: </strong>The mean age was 33.8±22.3y (range: 5-82y), with 27 females and 25 males. Median follow-up duration was 18.0mo [interquartile range (IQR) 7.0-41.5] for the non-surgical group and 15.0mo (IQR 9.0-48.0) for the surgical group. The surgical group demonstrated significantly greater BCVA improvement (mean change: -0.40±0.56 logMAR) compared with the non-surgical group (mean change: -0.03±0.19 logMAR; <i>P</i>=0.006). SFCT remained stable in the non-surgical group (mean change: +4.6±36.4 µm, <i>P</i>=0.74), and showed a greater decrease in the surgical group [mean change: -24.6 µm, 95% confidence interval (CI) -51.4 to +2.2 µm; <i>P</i>=0.06]. CMT decreased significantly in the surgical group (mean change: -392.2±287.9 µm, <i>P</i><0.001), whereas it remained stable in the non-surgical group (mean change: -79.7±233.4 µm, <i>P</i>=0.09). Spontaneous subretinal fluid reduction was observed in 25.9% (<i>n</i>=7) of non-surgical eyes, compared with 72.0% (<i>n</i>=18) of surgical eyes (<i>P</i><0.001), including complete fluid disappearance in 40.0% (<i>n</i>=10) of surgical cases.</p><p><strong>Conclusion: </strong>Surgical intervention appears more effective than conservative management in achieving subretinal fluid reduction and BCVA improvement in eyes with ODP-M.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"2018-2025"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008302","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Endophthalmitis caused by <i>Streptococcus dysgalactiae</i> subsp. <i>dysgalactiae</i> after cataract surgery: an unusual case report.","authors":"Dan-Dan Tian, Le-Han Hao, Chang-Rui Wu, Cheng Pei","doi":"10.18240/ijo.2026.10.24","DOIUrl":"10.18240/ijo.2026.10.24","url":null,"abstract":"","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"2083-2086"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A simplified slipknot technique for pupilloplasty in the treatment of mydriasis.","authors":"Yan-Bo Bao, Yi-Fei Tang, Su-Yu Liu, Zi-Fang He, Ya-Jun Liu, Qing-Hua Yi, Zheng-Gao Xie","doi":"10.18240/ijo.2026.10.15","DOIUrl":"10.18240/ijo.2026.10.15","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the surgical outcomes of a simplified slipknot pupilloplasty technique for repairing mydriasis, with a focus on postoperative visual recovery, pupil morphological stability, knitting efficiency and knot security.</p><p><strong>Methods: </strong>This prospective case series included patients with mydriasis due to trauma, glaucoma attack or iatrogenic damage, who underwent pupilloplasty (with or without intraocular lens implantation) from October 2022 to July 2025. Postoperative follow-ups were performed at 1, 3, 6, and 12mo. All cases had a minimum follow-up period of 3mo (range 3-12mo). Parameters recorded included best-corrected visual acuity (BCVA, logMAR), pupil diameter, and intraocular pressure (IOP).</p><p><strong>Results: </strong>A total of 32 consecutive patients (32 eyes, 21 males) were included. The mean age was 57.9±15.9y (21 to 85y). The simplified slipknot technique resulted in significant visual improvement: the mean preoperative logMAR BCVA was 1.15±0.79 (range, 0.22 to 2.5), which improved to 0.35±0.32 (range, 0 to 1.398) postoperatively. Postoperative pupil diameter remained stable, with a mean of 3.0±0.5 mm (range, 2.5 to 4 mm). The duration of the pupilloplasty was 4.3±0.5min and there was no loosening or shedding of the line knot in any case.</p><p><strong>Conclusion: </strong>The simplified slipknot technique has a similar treatment effect and safety as the traditional technique but requires a shorter time and is easier to perform in pupilloplasty surgery. It causes minimal trauma to intraocular tissues, and is easy to popularize.</p>","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"2003-2009"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586955/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Angiogenesis-RNA modification in diabetic retinopathy: biomarkers and targets.","authors":"Xue Wang, Dan-Ping Wu, Wei Du, Rui Li, Wei Lou, Ran-Ran Chen, Yu-Jie Liao, Qian Li, Xiao-Mei Li, Hong-Ping Cui, Jin-Ling Zhang","doi":"10.18240/ijo.2026.10.05","DOIUrl":"10.18240/ijo.2026.10.05","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Aim: &lt;/strong&gt;To identify biomarkers and potential therapeutic targets related to angiogenesis and RNA modification in diabetic retinopathy (DR).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;The Gene Expression Omnibus (GEO) datasets GSE12610, GSE87433, and GSE111465, which contain retinal samples from diabetic and normal mice, were analyzed to identify differentially expressed genes (DEGs). The DEGs were then intersected with angiogenesis- and RNA modification-related genes (A&RMRGs) obtained from GeneCards and other databases to identify differentially expressed A&RMRGs in DR. Hub genes were subsequently identified from the protein-protein interaction (PPI) network built on the enrichment results. Their diagnostic value was then estimated by receiver operating characteristic (ROC) analysis, and their expression levels were tested for associations with immune cell infiltration. Regulatory networks of hub genes were constructed using MicroRNA Target Prediction Database (miRDB), ChIPBase, and the Comparative Toxicogenomics Database (CTD). To validate the bioinformatic findings, hub gene transcript levels were quantified with reverse transcription quantitative polymerase chain reaction (RT-qPCR) in high-glucose-treated rat retinal microvascular endothelial cells (rRMECs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Forty-two A&RMRGs showed differential expression in the diabetic retina, with Gene Ontology (GO)/Kyoto Encyclopedia of Genes and Genomes (KEGG) enrichment implicating RNA modification and immune-inflammatory regulation, alongside Gene Set Enrichment Analysis (GSEA) evidence of activated RNA-silencing and fatty-acid-transport programs and suppressed neuronal and retinoid-cycle programs. Seven hub genes (&lt;i&gt;Wdr3&lt;/i&gt;, &lt;i&gt;Crebbp&lt;/i&gt;, &lt;i&gt;Sdad1&lt;/i&gt;, &lt;i&gt;Stat3&lt;/i&gt;, &lt;i&gt;Gnl2&lt;/i&gt;, &lt;i&gt;Nhp2&lt;/i&gt;, and &lt;i&gt;Hsp90aa1&lt;/i&gt;) were selected, all of them were upregulated in DR. The DR retina showed higher levels of central memory CD8&lt;sup&gt;+&lt;/sup&gt; T cells and lower levels of monocytes, Tregs, and CD56&lt;sup&gt;bright&lt;/sup&gt; natural killer (NK) cells. Monocyte infiltration was inversely associated with &lt;i&gt;Stat3&lt;/i&gt; expression (&lt;i&gt;r&lt;/i&gt;=-0.604, &lt;i&gt;P&lt;/i&gt;&lt;0.001), and central memory CD8&lt;sup&gt;+&lt;/sup&gt; T cell levels were positively associated with &lt;i&gt;Nhp2&lt;/i&gt; expression (&lt;i&gt;r&lt;/i&gt;=0.539, &lt;i&gt;P&lt;/i&gt;=0.003). A total of 60 miRNAs, 43 transcription factors (TFs), and 47 drugs may regulate RNA modification of angiogenesis-associated genes in DR. &lt;i&gt;Gnl2&lt;/i&gt; [area under the ROC curve (AUC)=0.914, 95% confidence interval (CI): 0.810-1.000) and &lt;i&gt;Stat3&lt;/i&gt; (AUC=0.964, 95%CI: 0.892-1.000) showed high diagnostic value. Exposure of rRMECs to high glucose led to a marked rise in &lt;i&gt;Stat3&lt;/i&gt; expression and a fall in &lt;i&gt;Sdad1&lt;/i&gt;, leaving the transcript levels of the remaining five hub genes unchanged.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;These findings identify &lt;i&gt;Stat3&lt;/i&gt; as a point of convergence between RNA modification, immune dysregulation, and angiogenesis, nominating the hub genes as candidate biomar","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"1914-1928"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586933/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on: \"Conjunctival microbiota variations in a subset of middle-aged and elderly individuals from Beijing, China\".","authors":"Omer Faruk Yilmaz, Abdurrahman Sarmis, Muhammed Ali Mutlu, Serap Karaca","doi":"10.18240/ijo.2026.10.26","DOIUrl":"10.18240/ijo.2026.10.26","url":null,"abstract":"","PeriodicalId":14312,"journal":{"name":"International journal of ophthalmology","volume":"19 10","pages":"2091-2092"},"PeriodicalIF":2.0,"publicationDate":"2026-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13586951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149008553","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}