ChemElectroChem最新文献_第3页

High Sensitivity L-Cysteine Indium Telluriselenide Quantum Dot-Inspired Aptasensor for Interferon Gamma TB Biomarker 高灵敏度l -半胱氨酸碲化铟量子点启发的干扰素γ结核生物标志物适配体传感器

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-06-11 DOI: 10.1002/celc.202400654

Kaylin Cleo Januarie, Usisipho Feleni, Candice Cupido, Nelia Abraham Sanga, Rachel Fanelwa Ajayi, Emmanuel Iheanyichukwu Iwuoha, Marlon Oranzie, Jaymi Leigh January, Zandile Dennis Leve

{"title":"High Sensitivity L-Cysteine Indium Telluriselenide Quantum Dot-Inspired Aptasensor for Interferon Gamma TB Biomarker","authors":"Kaylin Cleo Januarie, Usisipho Feleni, Candice Cupido, Nelia Abraham Sanga, Rachel Fanelwa Ajayi, Emmanuel Iheanyichukwu Iwuoha, Marlon Oranzie, Jaymi Leigh January, Zandile Dennis Leve","doi":"10.1002/celc.202400654","DOIUrl":"https://doi.org/10.1002/celc.202400654","url":null,"abstract":"Tuberculosis (TB) continues to be a significant contributor to global death tolls among infectious diseases. It can be diagnosed using certain cytokines, such as interferon-gamma (IFN-γ). Interferon-gamma is an essential component of the immune system's defense against pathogens which is known to be expressed in TB infection. This work involves the development of a quantum dot-sensitized electrochemical aptasensor for IFN-γ. The sensor system consists of gold disc electrode surface that was modified with novel L-cysteine-functionalized indium telluriselenide quantum dots (L-cysteine-InTeSe QD). Subsequently, the L-cysteine-InTeSe QDs are conjugated to an amine-terminated IFN-γ aptamer through a carbodiimide-mediated amide bond formation. The electrochemical responses of the IFN-γ aptasensor are studied by voltammetry. A linear calibration curve is generated for the concentration range studied (i.e., 10–21 pg mL−1 IFN-γ), and a limit of detection of 0.312 pg mL−1 is obtained. The QD aptasensor is able to accurately detect IFN-γ without interference from other substances. In a practical application using synthetic human serum, the QD aptasensor produced good detection recovery of 98–102%, highlighting its potential for diagnosing infectious diseases.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 15","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202400654","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Alternative Mechanistic Paradigm for the Electrochemical C-Terminal Decarboxylation of Peptides 多肽c端电化学脱羧的另一种机制范式

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-06-11 DOI: 10.1002/celc.202500142

Adam J. Sowers, Kevin D. Moeller, Kim S. Halskov

{"title":"An Alternative Mechanistic Paradigm for the Electrochemical C-Terminal Decarboxylation of Peptides","authors":"Adam J. Sowers, Kevin D. Moeller, Kim S. Halskov","doi":"10.1002/celc.202500142","DOIUrl":"https://doi.org/10.1002/celc.202500142","url":null,"abstract":"The C-terminal decarboxylation of peptides provides an important opportunity to synthesize modern peptide pharmaceuticals that contain C-terminal amides. This transformation can be achieved by electrochemical oxidation; however, the standard implementation depends on oxidation potential for selectivity which may represent a challenge when amino acid residues containing electroactive side chains are present. To address this limitation, an alternative mechanistic paradigm has been introduced for selective decarboxylation of a C-terminal carboxylate, one that relies on a chelation event. In a proof-of-principle experiment used to probe and define the viability of this mechanism, it is demonstrated that the combination of an iron mediator and a C-terminal glutamate residue can be used to conduct the reaction in the presence of the more electron-rich tyrosine residue frequently found in medicinally active peptides. Investigations into the reaction specifics and the scope/limitations provide key insights into the reaction mechanism and how such processes can be optimized. The success of the method highlighted here points to a more general binding-based approach to drive C-terminal decarboxylation that utilizes a functional group motif not possible at any other position in a peptide.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 14","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500142","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Modification Mechanisms and Synergistic Effects of Nb/Al Codoping in High-Nickel Cathode Materials for Lithium-Ion Batteries 锂离子电池高镍正极材料中Nb/Al共掺杂的改性机理及协同效应

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-06-08 DOI: 10.1002/celc.202500125

Zailun Ma, Jiashu Yuan

{"title":"Modification Mechanisms and Synergistic Effects of Nb/Al Codoping in High-Nickel Cathode Materials for Lithium-Ion Batteries","authors":"Zailun Ma, Jiashu Yuan","doi":"10.1002/celc.202500125","DOIUrl":"https://doi.org/10.1002/celc.202500125","url":null,"abstract":"Advanced medical imaging systems require exceptional reliability and extended service life. While high-nickel layered cathode materials (Li[NixCoyMn1−x−y]O2, Ni ≥ 80%) offer high energy density, their structural instability threatens critical medical operations. This study addresses the challenges of electrochemical performance and structural stability in high-nickel layered cathode materials. A codoping strategy using Nb5+ and Al3+ is employed to deeply explore the modification mechanisms and synergistic effects. The results indicate that Nb5+ doping induces a contraction of the primary particles, which enhances the crystal structure density and facilitates Li+ diffusion; however, it also increases Li+/Ni2+ cation mixing, potentially leading to irreversible capacity loss during the initial cycles. In contrast, the introduction of Al3+ effectively mitigates the cation mixing aggravated by Nb5+, maintaining the Li+/Ni2+ disorder within an optimal range. This adjustment significantly reduces electrode polarization during long-term cycling and prevents the formation of microcracks. Consequently, the codoped cathode half-cells retain 95.93% of their capacity after 200 cycles, while delivering a discharge capacity of 160.1 mAh g−1 at a 5 C rate. Moreover, both high-temperature and room-temperature performances are markedly improved. The synergistic effect of Nb5+ and Al3+ codoping not only stabilizes the layered structure but also enhances rate performance and cycle life.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 15","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500125","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Macroporous Hollow-Fibrous and Magnetically Recoverable TiO2 Catalysts for Converting Dye Wastewater to Valuable Resources 大孔中空纤维和磁可回收TiO2催化剂在染料废水资源化中的应用

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-06-05 DOI: 10.1002/celc.202500084

Xin Liu, Gonggang Liu, Shanshan Chang, Yuanyuan Liao, Jinbo Hu

{"title":"Macroporous Hollow-Fibrous and Magnetically Recoverable TiO2 Catalysts for Converting Dye Wastewater to Valuable Resources","authors":"Xin Liu, Gonggang Liu, Shanshan Chang, Yuanyuan Liao, Jinbo Hu","doi":"10.1002/celc.202500084","DOIUrl":"https://doi.org/10.1002/celc.202500084","url":null,"abstract":"The photocatalytic TiO2 has been regarded as a promising catalyst of nonbiodegradable organic pollutants in wastewater. Resolving some issues of agglomeration, recoverability, and poor efficiency, an inorganic TiO2-based catalyst has been constructed by a template method, which picks out bamboo fibers originating from processing waste. Characterization of the hollow fibrous TiO2/Fe3O4 catalyst confirms the successful loading of Fe3O4 and TiO2, along with a well-developed macroporous structure and high porosity (67.46%). At a solar intensity of 1 kW/m2, when the amount of TiO2/Fe3O4 is 0.3 g and the amount of H2O2 added is 3 mL, its degradation effect of 88.36% on industrial dye wastewater is optimal. The high magnetic saturation strength (5.78 emu/g) endows TiO2/Fe3O4 with ultra-high magnetic properties. As expected, after 10 catalytic cycles, the average degradation rate of TiO2/Fe3O4 toward methylene blue (MB) (0.2 L, 10 mg/L) remains above 96.2%, indicating that TiO2/Fe3O4 has ultra-high recyclability and repeatability. Furthermore, the degradation kinetics analysis shows that TiO2/Fe3O4 exhibits complete degradation of MB within 1 h and the degradation follows quasi-primary kinetics (k = 06062 min−1, R2 = 0.99747). Free radical burst experiments also indicate that hydroxyl radicals are active species that may play a major role in the solar-photo-Fenton system.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 14","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-06-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500084","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144598356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrochemically Produced pH Change Triggering Doxorubicin Release from Cystamine Cross-Linked Microgels Covalently Immobilized on the Gold Interface 电化学产生的pH变化触发了在金界面上共价固定的半胺交联微凝胶释放阿霉素

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-05-28 DOI: 10.1002/celc.202500128

Maria Sawicka, Patrycja Koscielniak, Ilya Sterin, Kamil Marcisz, Klaudia Kaniewska, Marcin Karbarz, Evgeny Katz, Oleh Smutok

{"title":"Electrochemically Produced pH Change Triggering Doxorubicin Release from Cystamine Cross-Linked Microgels Covalently Immobilized on the Gold Interface","authors":"Maria Sawicka, Patrycja Koscielniak, Ilya Sterin, Kamil Marcisz, Klaudia Kaniewska, Marcin Karbarz, Evgeny Katz, Oleh Smutok","doi":"10.1002/celc.202500128","DOIUrl":"https://doi.org/10.1002/celc.202500128","url":null,"abstract":"Herein, the usage of polyacrylic acid (AA) based and N,N′-bis(acryloyl)cystamine (BAC) cross-linked microgel (AA-BAC) as a doxorubicin (DOX) carrier and stimuli-responsive material for the controllable drug release is described. The carboxylic groups of AA provide a pH-responsive and DOX-holding ability of the polymer matrix, while sulfur groups of BAC provide a covalent immobilization of the AA-BAC microgel onto the gold electrode surface. The microgel is responsive to electrochemically generated pH decrease due to ascorbate oxidation. As a result of the local pH drop on the electrode interface electrostatic attraction between the carrier and the positively charged DOX diminishes, which together with the shrinkage of the matrix results in the controlled release of DOX from the microgel. The electrodes modified by microgel based on N,N′-methylene-bis-acrylamide (BIS) as a crosslinker are used as a control. However, AA-BIS microgel does not contain sulfur groups and it can only be not explicitly adsorbed on the gold electrode while the efficacy of this modification is significantly worse compared to covalent immobilization of AA-BAC via sulfur groups of BAC. Thus, electrode surface area covered by adsorbed (AA-BIS)-DOX microgel is approximately estimated as 34% compared to 90% for covalently immobilized (AA-BAC)-DOX microgel.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 15","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500128","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144705392","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Electrochemical Characterization of Functionalized Isoindolinones 功能化异吲哚酮的电化学表征

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-05-27 DOI: 10.1002/celc.202500044

Daniel. E. Smith, Ashley J. Basson, Niamh J. Owen, Mark Potter, Mark G. McLaughlin, Kathryn E. Toghill

引用次数: 0

Electrochemistry and Antioxidant Activities of Substituted Furanyl Nitrone: The Role of the Nitro Group 取代呋喃基硝基的电化学及抗氧化活性：硝基的作用

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-05-26 DOI: 10.1002/celc.202500068

Danyelle Cândido Santos, Débora de Souza dos Santos Costa, Paulo R. R. Costa, Ayres Guimarães Dias, Messias de Oliveira Silva, Taualia Achira Aly, Vinícius Del Colle, Jadriane Almeida Xavier, Marília O. F. Goulart, Thaissa Lúcio Silva

{"title":"Electrochemistry and Antioxidant Activities of Substituted Furanyl Nitrone: The Role of the Nitro Group","authors":"Danyelle Cândido Santos, Débora de Souza dos Santos Costa, Paulo R. R. Costa, Ayres Guimarães Dias, Messias de Oliveira Silva, Taualia Achira Aly, Vinícius Del Colle, Jadriane Almeida Xavier, Marília O. F. Goulart, Thaissa Lúcio Silva","doi":"10.1002/celc.202500068","DOIUrl":"https://doi.org/10.1002/celc.202500068","url":null,"abstract":"This work compares electrochemical and antioxidant data for synthetic furfural-derived nitrone (LQB-109), the novel N-methyl-nitroaryl-furanyl-nitrone (LQB-569), and the parent aldehyde (5NBFAL). Cyclic voltammograms (CVs) are obtained on a glassy carbon electrode (GCE) in acetonitrile (MeCN) and 0.1 mol L−1 n-Bu4NPF6 versus Ag|AgCl|Cl−, to evaluate cathodic and anodic behavior and chemical processes. The CVs of LQB-109 display two irreversible cathodic waves at −2.04 V and − 2.19V, related to a four-electron reduction to hydroxylamine. Two anodic waves appeared at +1.32 V and +1.53 V. The first electron uptake for LQB-569 occurs in the nitroaromatic group, followed by reductions to give a more electrophilic nitroso, prone to dimerizing and forming reducible azoxy derivatives, along with nitrone reduction, in a 10-electron total process. One irreversible anodic wave at +1.45 V appears, related to the nitrone oxidation. The electrochemical oxidation profile can be correlated to antioxidant capacity (AO). The ability to scavenge 2,2-diphenil-1-picrylhydrazyl (DPPH)• radicals (% radical scavenging activity) and reduce ferric complexes (ferric-reducing antioxidant power) were used to assess. LQB-569 showed low AO, due to the presence of the electron-withdrawing group, reflecting the oxidative part of the CVs.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 13","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144551295","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Synthesis and Electrochemical Investigations of a Binuclear [FeFe]-Hydrogenase Mimic 双核[FeFe]-氢化酶模拟物的合成及电化学研究

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-05-24 DOI: 10.1002/celc.202500050

Benedikt Callies, Kai-Thorben Kuessner, Sven T. Stripp, Stephan Kupfer, Phil Köhler, Helmar Görls, Inke Siewert, Wolfgang Weigand

{"title":"Synthesis and Electrochemical Investigations of a Binuclear [FeFe]-Hydrogenase Mimic","authors":"Benedikt Callies, Kai-Thorben Kuessner, Sven T. Stripp, Stephan Kupfer, Phil Köhler, Helmar Görls, Inke Siewert, Wolfgang Weigand","doi":"10.1002/celc.202500050","DOIUrl":"https://doi.org/10.1002/celc.202500050","url":null,"abstract":"Herein, a [FeFe]-hydrogenase mimic with the benzene-1,2-dithiolato ligand bearing two amino groups in 4- and 5-position of the ligand is reported. The ligand synthesis is straight forward and accomplished in two steps. Detailed studies show that the implementation of the functional groups in the [FeFe]-hydrogenase mimic has marginal impact on the structural, thermodynamic properties, and catalytic performance in the electrochemical proton reduction reaction. However, the modification opens the way for a wide variety of functionalization in the ligand backbone, e.g., for applications in photo/electrocatalysis. Electrochemical investigations reveal that initial two electron reductions are followed by protonation by acetic acid forming an asymmetric diironhydride species. Further reduction of the hydride species and protonation leads to H2 formation. Utilizing foot of the wave analysis, a reaction rate of 2 × 108 s−1 m−1 for the H2 evolution step consisting of the reaction of the metal hydride species and the external acid has been determined. However, catalysis is limited by the formation of the hydride at a rate constant of about 4 × 104 s−1 m−1.","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"12 12","pages":""},"PeriodicalIF":3.5,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144256577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Front Cover: Probing the Properties of Locally Formed Solid Electrolyte Interphases on Hard Carbon Anodes (ChemElectroChem 10/2025) 封面：探测硬碳阳极上局部形成的固体电解质界面的性质（ChemElectroChem 10/2025）

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-05-24 DOI: 10.1002/celc.202581001

Dr. Salimeh Saleh, Dr. Sven Daboss, Tom Philipp, David Schäfer, Prof. Dr. Marcus Rohnke, Prof. Dr. Christine Kranz

引用次数: 0

Ni-Based Catalysts for 5-Hydroxymethylfurfural Electrooxidation Coupled with Hydrogen Production 镍基5-羟甲基糠醛电氧化偶联制氢催化剂

IF 3.5 4区化学

ChemElectroChem Pub Date : 2025-05-21 DOI: 10.1002/celc.202500067

Itzcóatl Rafael Garduño-Ibarra, Zhigang Yan, Sayed Ahmed Ebrahim, Elena Baranova, Jesús González-Cobos, Mathieu Prévot, Philippe Vernoux

引用次数: 0