ChemElectroChem最新文献

{"title":"Nanoassemblies of an Artificial Ferric Enterobactin Analog for Biosensing Enterobacteriaceae","authors":"Selina Laws,&nbsp;Ndepana Andrew,&nbsp;Robson L. Grosso,&nbsp;Matthew Carnaghi,&nbsp;Hemali Rathnayake","doi":"10.1002/celc.202500442","DOIUrl":"10.1002/celc.202500442","url":null,"abstract":"<p>Natural enterobactin is an essential secondary metabolite secreted by Enterobacteriaceae to acquire nutrient iron in the form of Fe(III) from their environment. Its highly specific molecular recognition of Fe(III), followed by rapid uptake through receptor proteins on the bacterial cell wall, presents an attractive platform for biosensing Gram-negative bacteria. However, the structural complexity, delayed response times, and limited stability of natural enterobactin and conventional biological aptamers constrain their effectiveness in real-time sensing applications. To address these challenges, we report the design and synthesis of a simple synthetic enterobactin analog, tris-(2,3-dihydroxybenzamide)ethylamine (TDBEA), featuring a tethered trisamine scaffold that replaces the native trislactone macrocycle while retaining rapid receptor recognition. An aqueous, metal-ion-directed self-assembly strategy was employed to generate nanoassemblies from the ferric complex, Fe(III)–TDBEA. Structural characterization confirms that Fe³⁺ is hexacoordinated by triscatecholate motifs, yielding an empirical formula of C₂₇H₂₄FeN₄O₉. Electrochemical sensors fabricated from both the Fe(III)–TDBEA complex and its nanoassemblies exhibit distinct electrochemical responses upon exposure to live <i>Escherichia coli</i>. The sensors fabricated from the nanoassemblies show a threefold reduction in anodic peak current within 10 min, demonstrating rapid and sensitive detection. These results highlight the potential of TDBEA-based nanoassemblies as effective diagnostic tools for the rapid identification of pathogenic Enterobacteriaceae.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500442","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147683529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Strategies for Designing Cryogenic Aqueous Zinc-Ion Batteries: From Electrode Engineering to Electrolyte Optimization","authors":"Zeyu Zhu,&nbsp;Jingxuan Pan,&nbsp;Haoran Ma,&nbsp;Chuanbiao Zhang,&nbsp;Xiaoting Chen,&nbsp;Zhiyuan He","doi":"10.1002/celc.70185","DOIUrl":"10.1002/celc.70185","url":null,"abstract":"<p>Aqueous zinc-ion batteries (AZIBs) have emerged as a prominent energy storage solution due to their high theoretical capacity, environmental benignity, and cost-effectiveness. However, their practical application at low temperatures is severely hindered by electrolyte freezing, exacerbated dendrite growth, and sluggish ion diffusion kinetics. This review systematically discusses design strategies for freeze-tolerant AZIBs from both electrode and electrolyte perspectives. We first focus on electrode modifications, including ionic doping and defect engineering for manganese- and vanadium-based cathodes, alongside protective strategies for Zn anodes to mitigate dendrite formation at subzero conditions. We then examine electrolyte engineering, focusing on lowering freezing points and suppressing hydrogen bond formation through “water-in-salt” systems, additives, and hydrogel networks. By highlighting recent advances and identifying future research directions, this review provides a multidimensional perspective on developing reliable, cold-resilient AZIBs for diverse real-world employments.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.70185","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147683379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Front Cover: LiCrxFeyMn2−x−y−zTizO4 Spinels as Cathodes for Li-Ion Batteries: A Multidoping Approach to Suppress Jahn–Teller Distortion (ChemElectroChem 7/2026)","authors":"Daniele Callegari,&nbsp;Mauro Coduri,&nbsp;Mattia Canini,&nbsp;Luca Olivi,&nbsp;Maurizio Polentarutti,&nbsp;Giorgio Bais,&nbsp;Paolo Ghigna,&nbsp;Umberto Anselmi-Tamburini,&nbsp;Martina Fracchia","doi":"10.1002/celc.70199","DOIUrl":"https://doi.org/10.1002/celc.70199","url":null,"abstract":"<p>A magnifying glass symbolizes the structural insights gained through X-ray diffraction and operando X-ray absorption spectroscopy, enabling detailed understanding of the structural evolution and redox mechanisms of the multicomponent spinel during cycling. These complementary techniques reveal how the multidoping approach suppresses Jahn-Teller distortion, preserves structural integrity, and enhances the reversibility of the Mn(III)/Mn(IV) and Mn(II)/Mn(III) redox couples, leading to improved structural stability.\u0000 <figure>\u0000 <div><picture>\u0000 <source></source></picture><p></p>\u0000 </div>\u0000 </figure></p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.70199","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147683033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relaxation of Electrochemically Induced Intermediate States Under Non-Operando Conditions","authors":"Wulyu Jiang,&nbsp;Fei Tang,&nbsp;Tian Liu,&nbsp;Lu Xia,&nbsp;Lin Gan","doi":"10.1002/celc.202600006","DOIUrl":"https://doi.org/10.1002/celc.202600006","url":null,"abstract":"<p>Electrochemical polarization under oxygen evolution conditions often induces structural reconstruction from the parent phase in transition-metal-based catalysts, which are frequently interpreted as active intermediate species. Here, we investigate the relaxation behavior of electrochemically induced intermediates in spinel and hydroxide catalysts at controlled non-operando conditions by correlated spectroscopy and microscopy techniques. The oxyhydroxide phase formed at high anodic potentials remains stable after potential removal as long as electrochemical environments are maintained. In contrast, once the electrode is disconnected and the electrolyte is gradually removed, the intermediate state progressively relaxes back to the parent structure. Further drying treatments reveal that decreasing electrolyte activity markedly accelerates such structural recovery. These findings demonstrate that electrochemically induced intermediate structures should be regarded as boundary-condition-dependent states rather than intrinsically stable phases, highlighting the strong environment dependence of catalyst structural insights obtained under non-operando conditions.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202600006","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147683034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metal Organic Framework-Modified Carbon Fiber Microelectrodes for Enhanced Neurochemical Detection","authors":"Teflah Alshammari,&nbsp;Daniel Coughlin,&nbsp;Nadrah Aldaeefi,&nbsp;Nadiah Alyamni,&nbsp;Alexander G. Zestos","doi":"10.1002/celc.202500452","DOIUrl":"10.1002/celc.202500452","url":null,"abstract":"<p>Neurochemical detection with fast scan cyclic voltammetry (FSCV) and carbon fiber microelectrodes (CFMEs) often lacks sufficient sensitivity and selectivity for measuring low dopamine levels found in the brain. In this study, CFMEs were modified with the iron-based metal organic framework (MIL-88B(Fe)) to alter the electrode surface and improve dopamine detection performance. When tested with a triangle waveform (scanning from −0.4 to +1.3 V, 400 V s⁻¹, 10 Hz), MIL-88B(Fe)-modified CFMEs showed a higher oxidative peak current for dopamine, increasing from 57.0 ± 5 nA on bare CFMEs to 100.5 ± 5 nA dopamine (<i>n</i> = 7, <i>p </i>&lt; 0.0001), corresponding to an enhancement of ≈76%. These modified electrodes exhibited a linear response in the nanomolar dopamine range (10–100 nM), with sensitivity increasing from 30 ± 2 nA/µM for bare CFMEs to 49 ± 3 nA/µM for MIL-88B(Fe)-modified CFMEs, and a limit of detection of 53 nM (3.3 <i>σ</i>/S) with a limit of quantification of 162 nM. The electrodes simultaneously detected dopamine, tyrosine, and hydrogen peroxide, with distinct oxidation peaks and a high recovery rate (≈97%) in biological fluid. Together, these results indicate improved dopamine sensitivity relative to bare CFMEs and demonstrate the ability to distinguish dopamine from co-detected species with FSCV.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500452","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147682930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent Advances and Future Prospects of Rare Earth-Modified Aqueous Zinc-Ion Batteries","authors":"Wenshuo Zhang,&nbsp;Zhichao Zeng,&nbsp;Jing Zhao,&nbsp;Chao Li,&nbsp;Xiaomeng Shi,&nbsp;Siyuan Qu,&nbsp;Yaping Du","doi":"10.1002/celc.202500479","DOIUrl":"10.1002/celc.202500479","url":null,"abstract":"<p>Aqueous zinc-ion batteries (AZIBs) have emerged as promising candidates for large-scale energy storage due to inherent advantages including low cost, high safety, and environmental friendliness. However, their industrialization remains hindered by critical challenges such as dendrite growth on zinc anodes, hydrogen evolution reactions, corrosive side reactions, cathode structural degradation, and inadequate ion diffusion kinetics. To address these challenges, rare earth (RE) elements (e.g., Sc, Y, La, Ce, Eu), leveraging their high charge density, unique electronic configurations, and structural stability, have emerged as promising mediators for modulating interfacial electrochemistry, optimizing ion transport dynamics, and enhancing electrode stability in AZIBs. This review comprehensively summarizes recent advances in RE-modified AZIBs, focusing on their mechanisms in stabilizing cathodes, suppressing anode side reactions, and electrolyte engineering. It also provides key insights for future research directions on the role of REs in AZIBs.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500479","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147682931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nanostructured Carbon-Enhanced Positive Active Mass for Absorbent Glass Mat 2 V Lead Acid Batteries: Toward Improved Active Material Utilization, Extended Cyclability, and Reduced Water Loss","authors":"Marco Cattelan,&nbsp;Giorgia Daniel,&nbsp;Diego Zamboni,&nbsp;Daniele Fabris,&nbsp;Roberto Aliberti,&nbsp;Marco Mazzucato,&nbsp;Silvia Cazzanti,&nbsp;Christian Durante","doi":"10.1002/celc.202500472","DOIUrl":"10.1002/celc.202500472","url":null,"abstract":"<p>This article investigates the effects of three commercial carbon compounds—graphite, carbon black (CB), and carbon nanotubes (d-CNT)—on positive active material (PAM) utilization, cycling performance, and water consumption (WC) in 2 V absorbent glass mat lead–acid batteries (LABs). After an initial screening of these materials based on their physicochemical properties—such as surface area, porosity, degree of graphitization, conductivity, and contact angle (wettability)—the carbon additives were incorporated into positive electrodes during manufacturing and tested in cells with a 1+/2− configuration. Both <i>C</i>₂₀ and cold cranking tests revealed a significant increase in the specific discharge capacity of LABs containing d-CNT and graphite. Furthermore, LABs incorporating d-CNT or graphite exhibited an enhanced cyclability over other samples during the 50% depth-of-discharge test, also demonstrating a greater capacity to accept a larger charge during initial recharge. WC analysis, conducted in accordance with EN 50 342-1:2016−11 protocol, revealed reduced water loss, particularly in LABs with d-CNT, due to the increased recombination rate of hydrogen and oxygen resulting from electrolyte water electrolysis. Postmortem physicochemical analysis of the positive plates confirms these results. The CB-containing PAM exhibited the highest PbSO₄ content, with scanning electron microscopy revealing larger PbSO₄ crystallites on its surface. In contrast, graphite- and d-CNT-based samples showed smaller PbSO₄ particles randomly distributed over the PAM surface, whereas in the STD PAM, PbO₂ polymorphs covered larger PbSO₄ crystallites.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 8","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500472","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147682886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Real-Time Monitoring of Enzyme Conformational Transitions During Substrate Inhibition via Nanopipettes","authors":"Wen-Long Chen,&nbsp;Yang Luo,&nbsp;Si-Qi Chai,&nbsp;Cui-Ju Zhang,&nbsp;Si-Meng Deng,&nbsp;Ding-Cheng Wu,&nbsp;Ying-Yi Shi,&nbsp;Hui Ma","doi":"10.1002/celc.202500483","DOIUrl":"https://doi.org/10.1002/celc.202500483","url":null,"abstract":"<p>Acetylcholinesterase (AChE) substrate inhibition is a critical self-regulatory mechanism, yet its conformational dynamics at the single-molecule level remain elusive. Here, we report a label-free single-molecule assay using nanopipettes that resolves AChE conformational states in real time during substrate inhibition. By monitoring the ionic current signatures across a substrate concentration range of 1–50 mM, we distinguish between single- and dual-substrate binding states of individual AChE molecules. The blockade amplitude exhibits a clear nonmonotonic trend: it increases at low substrate concentrations (1–10 mM) and then decreases at 50 mM. This amplitude pattern correlates with the shift from monosubstrate to bisubstrate binding, reflecting a conformational transition from an expanded to a compact state that is consistent with the established dual-site inhibition model. These results provide direct single-molecule evidence linking specific substrate-occupancy states to distinct conformations underlying AChE inhibition. This nanopipette platform offers a sensitive, label-free strategy for probing conformational landscapes during enzyme catalysis and regulation.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500483","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147631865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"N,N’-Dialkylated Oxo-Verdazyl Radicals as Bipolar Organic Molecules for Symmetric Redox Flow Batteries","authors":"Elena S. Horst,&nbsp;Karin Sowa,&nbsp;Lena Lezius,&nbsp;Nick Fehlings,&nbsp;Constantin Daniliuc,&nbsp;Sascha Nowak,&nbsp;Mariano Grünebaum,&nbsp;Martin Winter,&nbsp;Armido Studer","doi":"10.1002/celc.202500465","DOIUrl":"https://doi.org/10.1002/celc.202500465","url":null,"abstract":"<p>The bipolar electrochemical properties of verdazyl radicals have long been known, and recently their application in symmetric redox flow batteries was investigated. However, the performance of aryl-substituted Kuhn- and oxo-verdazyl radicals in cycling experiments was unsatisfactory. In this work, <i>N</i>,<i>N’</i>-dialkylated oxo-verdazyl radicals were investigated as bipolar redox-active organic molecules (ROM). With a higher theoretical cell voltage than that of Kuhn- and arylated oxo-verdazyl radicals, these stable radicals revealed themselves a promising candidate for battery application. The initial tests of an <i>N</i>,<i>N’</i>-diisopropyl-verdazyl radical showed moderate cycling, stability and the formation of a new redox-active species during the cycling between neutral and cationic states was observed. By postcycling analysis, the decomposition product could be identified as the radical lacking an isopropyl group. By subsequent molecular engineering, the performance of the <i>N</i>,<i>N’</i>-dialkylated verdazyl radical could be improved by suppressing the decomposition pathway through variation of the N-substituent. Overall, the optimized verdazyl radical possesses a theoretical cell voltage of greater than 1.6 V. H-cell cycling experiments over 200 cycles showed an average Coulombic efficiency of 99.5% and a capacity fade of less than 0.1%/cycle for both oxidation and reduction. Finally, the best-performing oxo-verdazyl radicals were investigated under flow conditions.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-03-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500465","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147585073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fundamentals of MXene Synthesis Steps and Their Characterization Techniques: Morphological, Structural, and Electrochemical Properties","authors":"Yuksel Akinay,&nbsp;Mehmet Topuz,&nbsp;Erkan Karatas,&nbsp;Muhammet Enver Gokdemir,&nbsp;Tayfun Cetin,&nbsp;Safa Polat,&nbsp;Rashad Abaszade,&nbsp;Mukhtar Singh,&nbsp;Huseyn Imanov","doi":"10.1002/celc.202500468","DOIUrl":"https://doi.org/10.1002/celc.202500468","url":null,"abstract":"<p>MXene phases, a rapidly expanding family of two-dimensional transition metal carbides, nitrides, and carbonitrides, have grown to include more than 80 compositions since their discovery in 2011, owing to their exceptional electrical conductivity, tunable surface chemistry, and versatile functional properties that enable applications in energy storage, electromagnetic interference (EMI) shielding, biomedical technologies, and ultrasensitive sensing systems. Common acidic etching methods, coupled with highly sensitive process requirements, pose significant challenges limiting the scalable synthesis of MXene phases, particularly for mass production. This review presents a comprehensive evaluation of MXene synthesis, including acid etching and safer fluoride-free acid etching methods. hydrofluoric acid (HF)-etching, fluoride-free, molten salt, electrochemical, and hydrothermal methods are extensively discussed in terms of their respective advantages, limitations and their effects on surface terminations. Following etching, the subsequent stages of intercalation, delamination, and postsynthesis treatments are addressed to highlight strategies for achieving high-purity, stable, and single or few-layer MXene sheets while preserving their structural integrity and high quality. In addition, common characterization techniques such as X-ray diffraction (XRD), Scanning electron microscope (SEM), transmission electron microscopy (TEM), atomic force microscopy (AFM), X-ray photoelectron spectroscopy (XPS), and Fourier-transform spectroscopy (FTIR) are discussed comprehensively, and electrochemical performance methods—including band structure, cyclic voltammetry (CV), galvanostatic charge/discharge (GCD), and electrochemical impedance spectroscopy (EIS)—are evaluated to correlate the morphological features of MXene phases with functional properties.</p>","PeriodicalId":142,"journal":{"name":"ChemElectroChem","volume":"13 7","pages":""},"PeriodicalIF":3.5,"publicationDate":"2026-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/celc.202500468","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147585188","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}