International Journal of Retina and Vitreous最新文献

{"title":"Therapeutic interventions for chronic central serous chorioretinopathy: a comprehensive assessment of systematic reviews.","authors":"Henok Getahun, Rajendra S Apte","doi":"10.1186/s40942-025-00660-x","DOIUrl":"10.1186/s40942-025-00660-x","url":null,"abstract":"<p><strong>Background: </strong>A variety of different treatments have been proposed to effectively treat chronic central serous chorioretinopathy but there remains uncertainty regarding the efficacy of a number of treatment options. We aim to evaluate the efficacy of several therapeutic options for chronic central serous chorioretinopathy including photodynamic therapy, conventional laser photocoagulation, subthreshold micropulse laser, selective retina therapy, vascular endothelial growth factor (VEGF) antagonists, and mineralocorticoid receptor antagonists.</p><p><strong>Methods: </strong>Pubmed, Embase, and Cochrane databases were searched for systematic reviews and meta-analyses evaluating treatment modalities for chronic central serous chorioretinopathy. Primary outcome measures included improvement in best corrected visual acuity (BCVA) and resolution of subretinal fluid (SRF). Conclusions regarding the efficacy of each modality were summarized and compared to findings of several key randomized controlled trials.</p><p><strong>Results: </strong>Ten systematic reviews and meta-analyses that incorporated 58 unique randomized controlled trials and observational studies were identified. Treatments that were shown to improve BCVA and promote SRF resolution included half-fluence and half-dose photodynamic therapy, conventional laser therapy, and subthreshold micropulse laser therapy. Evidence regarding selective retina therapy was limited and inconclusive. VEGF antagonists were not effective in the absence of choroidal neovascularization and mineralocorticoid receptor antagonists were not effective.</p><p><strong>Conclusion: </strong>The most effective therapeutic option for chronic central serous chorioretinopathy is half-dose or half-fluence photodynamic therapy, however, conventional laser therapy is an acceptable alternative in cases when photodynamic therapy is unavailable and when fluid leakage sites are not subfoveal or juxtafoveal. Subthreshold micropulse laser is less effective but can be considered when other options are unavailable.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"34"},"PeriodicalIF":1.9,"publicationDate":"2025-03-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11931883/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143692022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of a multifocal electroretinogram to evaluate the therapeutic effect of a single intravitreal dexamethasone implant, Ozurdex^®, for refractory diabetic macular oedema.","authors":"Aya Refaat Ali Mohammed, Mohamed Farouk Sayed Othman, Yehia Mahmoud Khairat, Amr Ahmed Mohamed Abdelrahman","doi":"10.1186/s40942-025-00652-x","DOIUrl":"10.1186/s40942-025-00652-x","url":null,"abstract":"<p><strong>Aim: </strong>To evaluate the therapeutic effect of a single intravitreal dexamethasone implant (Ozurdex^®) in eyes with refractory diabetic macular oedema (DME) anatomically via optical coherence tomography (OCT) and functionally via best corrected visual acuity (BCVA) and multifocal electroretinography (mfERG).</p><p><strong>Methods: </strong>This prospective interventional study included twenty eyes with refractory DME that were treated using six intravitreal injections of anti-vascular endothelial growth factor (VEGF). The central retinal thickness (CRT) was measured via OCT exceeding 300 μm. The eyes were treated with a single dexamethasone (DEX) implant four weeks after the last injection of anti-VEGF. The outcomes included changes in CRT, BCVA and p1 amplitude of ring 1 on mfERG and intraocular pressure (IOP) recorded before injection and two, four and six months after DEX injection.</p><p><strong>Results: </strong>The study included fifteen males (75%) and five females (25%). The mean age was 62.83 ± 6.34 years, with the mean duration of diabetes was 16.7 ± 2.21 years. During the two-month follow-up, there were statistically significant reductions in CRT and logMAR BCVA as well as an increase in p1 of ring 1 on mfERG (P = 0.046, P < 0.001 and P < 0.001, respectively). At four months, these changes were not statistically significant (P = 0.99, P < 0.56&P < 0.58), whereas at six months, all the parameters nearly reached pre-DEX injection values (p = 0.93 P = 0.99 P = 0.81). The IOP values were not significantly increased at two, four or six months (p < 0.06, P = 0.35 and P = 1.0, respectively). There were significant negative correlations between the mfERG and OCT parameters before and six months after DEX injection (p = 0.000).</p><p><strong>Conclusion: </strong>A single intravitreal injection of DEX in refractory DME patients induced significant anatomical and functional improvements, but these improvements only lasted for short periods of up to four months. This treatment exhibited an excellent safety profile. However, at six months, the therapeutic effect was null. The utility of mfERG as a sensitive biomarker of treatment efficacy was highlighted herein.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"33"},"PeriodicalIF":1.9,"publicationDate":"2025-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921743/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143663240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative efficacy of half-dose and one-third-dose photodynamic therapy in chronic central serous chorioretinopathy: a retrospective study.","authors":"Mohsen Farvardin, Dorna Eghtedari, Maryam Shahmohammadi, Mohammadkarim Johari","doi":"10.1186/s40942-025-00657-6","DOIUrl":"10.1186/s40942-025-00657-6","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the efficacy and safety of half-dose and one-third-dose photodynamic therapy (PDT) with verteporfin in patients with chronic central serous chorioretinopathy (CSC).</p><p><strong>Methods: </strong>This retrospective study included 72 eyes from 72 patients with chronic CSC treated with either one-third-dose (2 mg/m²) or half-dose (3 mg/m²) PDT. Best-corrected visual acuity (BCVA), central retinal thickness (CRT), subretinal fluid (SRF) thickness, subfoveal choroidal thickness (SFCT), and optical coherence tomography (OCT) features were evaluated at baseline, 3 months, and 12 months. Fluorescein angiography (FA) was used to guide laser application. Treatment outcomes, including SRF resolution, BCVA gain, and recurrence rates, were compared between the two groups.</p><p><strong>Results: </strong>At 12 months, complete SRF resolution was achieved in 40 eyes (78.4%) in the half-dose group and 15 eyes (71.4%) in the one-third-dose group. The recurrence rate of SRF was significantly higher in the one-third-dose group (20%) compared to the half-dose group (7.5%) (P =.015). BCVA improved significantly in both groups, with mean increases from 72.4 ± 3.9 to 77.1 ± 5.6 letters in the one-third-dose group and from 74.4 ± 4.2 to 80.2 ± 2.19 letters in the half-dose group. The proportion of patients achieving a ≥ 10-letter gain was higher in the half-dose group (52%) compared to the one-third-dose group (28.5%, P =.001). Both groups exhibited significant reductions in CRT, SRF thickness, and SFCT (P <.001), with no significant intergroup differences. Baseline CRT and fluorescein leakage patterns influenced treatment response.</p><p><strong>Conclusions: </strong>Both one-third-dose and half-dose PDT effectively improved visual and anatomical outcomes in patients with chronic CSC. However, half-dose PDT demonstrated superior efficacy in achieving SRF resolution and greater visual acuity gains with a lower recurrence rate.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"32"},"PeriodicalIF":1.9,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11921750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143656995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Foveal crack sign and macular pattern dystrophy.","authors":"Rainer Rodriguez, David J Browning","doi":"10.1186/s40942-025-00655-8","DOIUrl":"10.1186/s40942-025-00655-8","url":null,"abstract":"<p><strong>Purpose: </strong>To determine if eyes with the foveal crack sign (FCS) in macular pattern dystrophy (MPD) progress to macular holes, and if FCS occurs in the context of hyperreflective foci (HRF) that do not reach the threshold of FCS.</p><p><strong>Patients and methods: </strong>A retrospective chart review of eyes with MPD was conducted in the Atrium Health Wake Forest Baptist medical system. 56 eyes from 32 patients identified as having macular pattern dystrophy were identified. Demographic data were collected from charts and spectral domain optical coherence tomographs (SD-OCTs) were analyzed.</p><p><strong>Results: </strong>8 eyes from 6 patients were found to have an FCS-positive OCT at any point at or following their initial diagnosis of MPD. One eye developed a full-thickness stage 4 macular hole during follow-up. There was no significant difference in macular hole development between MPD eyes with and without FCS (p =.1429). There was a significant difference in FCS development between MPD eyes with and without HRF (p =.0063).</p><p><strong>Conclusions: </strong>The data did not show a significant difference in macular hole generation between eyes with and without FCS, unlike the situation of FCS in eyes post vitrectomy for retinal detachment repair. The significant association between HRF and FCS suggests that the two signs may have a related pathophysiology and may represent different stages in a common degenerative process. Further work is needed to better characterize the relationship of FCS and HRF and to determine if FCS has different implications in the different clinical contexts in which it appears.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"31"},"PeriodicalIF":1.9,"publicationDate":"2025-03-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11912750/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143647425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Remote web-based self-assessment of visual acuity versus ETDRS in patients with macular diseases: a method comparison study.","authors":"Casper van der Zee, Leon Daniel Huang Huynh, Saskia Marijke Imhof, Jeannette Ossewaarde-van Norel, Redmer van Leeuwen, Robert Pieter Leendert Wisse","doi":"10.1186/s40942-025-00656-7","DOIUrl":"10.1186/s40942-025-00656-7","url":null,"abstract":"<p><strong>Background: </strong>Macular diseases (MD) lead to frequent clinic visits, involve time-consuming visual acuity (VA) measurements by professionals. Independent home measurements could improve efficiency. This study evaluates the agreement of a web-based test in MD compared to in-hospital measurements.</p><p><strong>Methods: </strong>Adults with MD were included at the University Medical Center Utrecht in March-July 2023. Users need a phone, computer, and 3m distance. The test uses Tumbling-E and triangles as optotypes. Primary outcome is the web-based vs. ETDRS Distance Visual Acuity (DVA). Secondary outcomes were test-retest variability (TRV), near visual acuity (NVA), and the Amsler grid. Outcomes were reported in mean differences and 95% Limits of Agreement (LoA).</p><p><strong>Results: </strong>89 eyes were included. The DVA mean difference was 0.03LogMAR(1.5 letters), SD0.17, LoA - 0.31;0.36LogMAR(-15.5;18 letters), TRV had a mean difference of 0.03(1.5 letters) SD0.14. The NVA mean difference was 0.13(6.5 letter) SD0.24, positive- and negative predictive values 0.93(95%CI = 0.82;0.98) and 0.71(95%CI = 0.51;0.86) respectively.</p><p><strong>Conclusions: </strong>The agreement of the DVA web-based test is on par with Snellen line assessment and subpar to ETDRS. We showed that elderly can perform this test independently at home, providing a time- and cost-saving opportunity. Developments should focus on the NVA since it can be a valuable adjunct to MD follow-up.</p><p><strong>Trial registration: </strong>the Dutch Medical Ethical committee (Medisch Ethische Toetsingscommissie; METC NedMec) registration number: 22-879/DB. Approved at 27-09-2022.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"29"},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907903/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of neural networks to determine factors affecting the severity and extent of retinopathy in preterm infants.","authors":"Mohammad Reza Mazaheri Habibi, Azadeh JafariMoghadam, Narges Norouzkhani, Elham Nazari, Bahareh Imani, Azam Kheirdoust, Seyed Ali Fatemi Aghda","doi":"10.1186/s40942-025-00650-z","DOIUrl":"10.1186/s40942-025-00650-z","url":null,"abstract":"<p><strong>Background: </strong>Retinopathy of prematurity (ROP) is a leading cause of visual impairment and blindness in preterm infants. Early identification of key risk factors is essential for effective screening and timely intervention. This study utilizes an artificial neural network (ANN) to analyze and identify the most influential factors affecting the severity and extent of ROP in preterm neonates.</p><p><strong>Methods: </strong>This descriptive-analytical study was conducted on 367 preterm infants in Bojnord, Iran, in 2021. The study examined multiple variables, including sex, history of multiple births, number of prior abortions, type of pregnancy and delivery, gestational age, oxygen therapy, severity of retinopathy, and disease extent within the retina. Statistical analyses were performed using one-way analysis of variance (ANOVA), Pearson's correlation coefficient, and an ANN to determine the relationships between independent variables and ROP progression.</p><p><strong>Results: </strong>The findings indicate that the severity of ROP was significantly associated with the type of pregnancy, gestational age, birth weight, and postnatal age (P < 0.05). Similarly, disease extent was significantly correlated with maternal parity, gestational age, birth weight, and postnatal age (P < 0.05). Among all factors examined, postnatal and gestational age exhibited the highest coefficient effects on ROP severity and disease extent. Additionally, follow-up evaluations revealed that infant age and birth weight were crucial in disease progression.</p><p><strong>Discussion: </strong>The results suggest that targeted interventions focusing on gestational age and neonatal weight may significantly reduce the incidence and severity of ROP in preterm infants. Integrating ANNs enhances predictive accuracy, enabling early diagnosis and improved clinical outcomes.</p><p><strong>Conclusion: </strong>The findings of this study contribute to the advancement of ROP screening and treatment strategies in preterm neonates. Future research should focus on multi-center studies with larger sample sizes to refine predictive models and identify additional risk factors influencing ROP progression.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"30"},"PeriodicalIF":1.9,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11909869/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143633917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"\"Setting the standard\": an analysis of different acquisition patterns for macular OCT-angiography.","authors":"Ramkailash Gujar, Giulia Gregori, Rosa Dolz-Marco, Alessio Muzi, Jay Chhablani, Daniela Fruttini, Lorenzo Mangoni, Clara Rizzo, Cesare Mariotti, Marco Lupidi","doi":"10.1186/s40942-025-00653-w","DOIUrl":"10.1186/s40942-025-00653-w","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to determine the optimal OCT angiography (OCT-A) scanning pattern using the SPECTRALIS HRA-OCT2 device to evaluate macular microvasculature perfusion in healthy subjects.</p><p><strong>Methods: </strong>Healthy subjects were imaged using the SPECTRALIS OCT-A Module (Heidelberg Engineering) with the following scanning protocols: 10ºX10º-512 ART 7 [P1], 10ºX10º-256 ART 5 [P2], 10ºX10º-512 ART 5 [P3], and 15ºX10º-256 ART 5 [P4], all centered on the macula. Vessel perfusion density (VPD) and vessel length density (VLD) of the superficial vascular complex (SVC) were calculated using ImageJ software to evaluate the differences between scanning patterns. Three additional 10ºx1º, ART 7 high-density images were also obtained using the in-built software (SP-X1701 Update 3, based on Heyex Software Version 1.9.215.0 H) in the macular area and the VPD and VLD for all the three10ºx1º pattern size images with the corresponding area of pattern 1 image[P1]. Two retinal specialists conducted a blind qualitative assessment of the foveal avascular zone and image quality.</p><p><strong>Results: </strong>Twenty eyes from 20 consecutive healthy patients were included in the study. The mean VPD for P1, P2, P3, and P4 were 35.60, 31.67, 31.18, and 31.16, respectively. Mean VLD for P1, P2, P3, and P4 were 7.54, 5.86, 6.74, and 4.40, respectively. Significant differences were found between P1 and the other patterns for both the VPD and VLD, but not between P2, P3, and P4. VPD and VLD for 10ºx1º high-density images were 33.20 and 4.61, respectively, with significant VLD differences compared to P1, but not for VPD. P1 scored the highest and P4 the lowest in the qualitative assessments.</p><p><strong>Conclusions: </strong>The 10ºX10º-512 ART 7 pattern showed statistically significant qualitative superiority and appeared optimal for blood flow detection with reduced noise in quantitative assessments.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"28"},"PeriodicalIF":1.9,"publicationDate":"2025-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11907780/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143624641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Correction: Impact of duration of treatments with metformin and sulfonylureas, individually or in combination, on diabetic retinopathy among newly diagnosed type 2 diabetic patients: a pooled cohort's analysis.","authors":"Mansour Bahardoust, Yadollah Mehrabi, Farzad Hadaegh, Davood Khalili, Ali Delpisheh","doi":"10.1186/s40942-025-00658-5","DOIUrl":"10.1186/s40942-025-00658-5","url":null,"abstract":"","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"27"},"PeriodicalIF":1.9,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11905429/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143615510","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Surgical management and long-term follow-up of ocular hypotony associated with peripheral circumferential retinal detachment.","authors":"Leandro Cabral Zacharias, Lívia da Silva Conci, Davi Paraguassu de Sousa Martins, Rony Carlos Preti, Leonardo Proveti Cunha, Mario Luiz Ribeiro Monteiro","doi":"10.1186/s40942-025-00648-7","DOIUrl":"10.1186/s40942-025-00648-7","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the surgical management and long-term follow-up of hypotony related to post-vitrectomy peripheral circumferential retinal detachment (PCD).</p><p><strong>Methods: </strong>Eyes diagnosed with hypotony secondary to PCD after pars plana vitrectomy were retrospectively reviewed. The patient demographic data, complications, management, and treatment outcomes were collected and analyzed.</p><p><strong>Results: </strong>Four eyes were included in this study. The median preoperative best-corrected visual acuity (BCVA) was 20/200 and the mean preoperative intraocular pressure (IOP) was 4.5 mmHg. One case had rubeosis iridis. All eyes underwent peripheral retinectomy to remove the detached retina and release ciliary body traction. Complete retinal reattachment was achieved in all eyes. The final BCVA ranged from 20/200 to 20/50 and regression of rubeosis iridis was observed. Mean IOP improved to 12,25 mmHg at 12 months after the retinectomy. The mean follow- up time was 5 years (range 2-7 years).</p><p><strong>Conclusion: </strong>Aggressive dissection and 360º trimming of the anterior retina is helpful to relieve ciliary body traction and remove ischemic tissue, restoring minimally adequate aqueous production in cases of hypotony related to PCD.</p><p><strong>Trial registration: </strong>This retrospective study was approved by the Institutional Review Board, under registration number 77599724.7.0000.0068.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"26"},"PeriodicalIF":1.9,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892287/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596933","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"New minimally invasive technique for repositioning of a subluxated retropupillary iris-claw IOL using needle-assisted fixation.","authors":"Celso Costa, Nuno Gouveia, Pedro Fonseca, Miguel Raimundo, Joaquim Murta, João Figueira","doi":"10.1186/s40942-025-00651-y","DOIUrl":"10.1186/s40942-025-00651-y","url":null,"abstract":"<p><strong>Purpose: </strong>This paper presents a modification of the needle-assisted retropupillary fixation technique for iris-claw intraocular lenses (IOLs). We introduce a novel, minimally invasive reenclavation technique for managing subluxated retropupillary iris-claw IOLs.</p><p><strong>Methods: </strong>The technique was successfully performed on four patients diagnosed with subluxated retropupillary iris-claw IOLs. This approach involved a novel, minimally invasive reenclavation technique that utilized three needles: one long, straight translimbal needle crossing the anterior chamber and two needles introduced through the pars plana to reposition and securely reenclavate the IOL.</p><p><strong>Results: </strong>All patients experienced immediate and significant visual recovery, with their baseline visual acuities reestablished postoperatively. Importantly, no post-operative complications were observed during the six-month follow-up period, highlighting the safety and efficacy of the technique.</p><p><strong>Conclusion: </strong>Our novel, minimally invasive technique for reenclavation of iris-claw IOLs, employing just three needles, eliminates the need for trocar insertion, infusion cannulas, or sutures. This approach offers significant advantages, including a shorter operative time and minimal surgical manipulation, leading to faster patient recovery and fewer complications.</p>","PeriodicalId":14289,"journal":{"name":"International Journal of Retina and Vitreous","volume":"11 1","pages":"25"},"PeriodicalIF":1.9,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11892194/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143596857","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}