Stress (Amsterdam, Netherlands)最新文献

{"title":"Caregiving stress and burden associated with cardiometabolic risk in family caregivers of individuals with cancer.","authors":"Lena J Lee, Youngmee Kim, Robert Shamburek, Alyson Ross, Li Yang, Margaret F Bevans","doi":"10.1080/10253890.2022.2037548","DOIUrl":"10.1080/10253890.2022.2037548","url":null,"abstract":"<p><p>Chronic stress is a well-established risk factor for cardiometabolic disease. Caregiving for individuals with cancer is perceived as a chronic stressor yet research on the risk for cardiometabolic disease in this population, opposed to the elderly and those with Alzheimer's disease, is limited. Additionally, few studies have explored the early physiological changes that occur in family caregivers suggesting an elevated risk for illness. This cross-sectional study was designed to examine levels of cardiometabolic risk biomarkers and their correlates in caregivers of patients with colorectal cancer. Caregivers completed questionnaires that measure exposures to stress and vulnerability factors, psychological distress, and health habits as potential correlates. Traditional lipid and nontraditional lipoprotein particle biomarkers (e.g. concentration and size for all lipoprotein classes) were assayed from blood serum. Caregivers (<i>N</i> = 83, mean age = 49.8, 73% female) displayed levels of cardiometabolic biomarkers that suggest an elevated risk for cardiometabolic disease. Caregivers who were Hispanic, married, highly educated, employed, reported more hours spent caregiving daily, experienced higher caregiver burden associated with the lack of family support and impact on schedule, and psychological distress, demonstrated an elevated risk for cardiometabolic disease; primarily determined by nontraditional lipid biomarkers - large TRL-P, LDL-P, small HDL-P, large HDL-P, TRL-Z, LDL-Z and HDL-Z. These findings suggest that traditional lipid biomarkers may not be robust enough to detect early physiological changes associated with cardiometabolic disease risk in family caregivers. Moreover, findings reiterate the importance of assessing caregiver burden and providing evidence-based interventions to manage caregiving stress with the potential to improve caregivers' cardiometabolic health.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"258-266"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9380420/pdf/nihms-1828027.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40122125","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differences in acute stress responses depending on first or second language in a Hispanic-American sample.","authors":"Felicitas Hauck,&nbsp;Lucía Romero Gibu,&nbsp;Silke Jansen,&nbsp;Nicolas Rohleder","doi":"10.1080/10253890.2022.2110466","DOIUrl":"https://doi.org/10.1080/10253890.2022.2110466","url":null,"abstract":"<p><p>Using a second language is a daily experience for many people today, among them many migrants. To determine whether speaking a second language induces a stronger cortisol or alpha-amylase (sAA) response than first language, we tested a Hispanic-American sample in two Trier Social Stress Test (TSST) conditions: First (Spanish) and second (German) language. Thirty-two participants (64.5% female) between the age of 19 and 53 years (mean = 30.68) from Latin America were tested (15 in Spanish, 17 in German). Participants were randomized to a German or Spanish version of the TSST, gave six saliva samples and completed questionnaires on perceived threat and stress, positive and negative affect as well as state-anxiety. A significantly higher stress response was found in the German condition for salivary cortisol, but not for sAA. Self-report showed significantly higher perceived threat and negative affect after the TSST for the German compared to the first language condition. Speaking a second compared to first language in a challenging situation appeared to be more stressful and threatening for participants. Further, reported increases in state-anxiety appeared to be higher in the German condition, even though group differences did not reach significance. A more detailed investigation of underlying, stress inducing mechanisms should be considered in future studies as well as associations with language proficiency and improvements over time.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"313-322"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40412935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Physiological behavior during stress anticipation across different chronic stress exposure adaptive models.","authors":"Dejana Popovic,&nbsp;Svetozar Damjanovic,&nbsp;Bojana Popovic,&nbsp;Aleksandar Kocijancic,&nbsp;Dragana Labudović,&nbsp;Stefan Seman,&nbsp;Stanimir Stojiljković,&nbsp;Milorad Tesic,&nbsp;Ross Arena,&nbsp;Ratko Lasica","doi":"10.1080/10253890.2021.2006178","DOIUrl":"https://doi.org/10.1080/10253890.2021.2006178","url":null,"abstract":"<p><p>Anticipation of stress induces physiological, behavioral and cognitive adjustments that are required for an appropriate response to the upcoming situation. Additional research examining the response of cardiopulmonary parameters and stress hormones during anticipation of stress in different chronic stress adaptive models is needed. As an addition to our previous research, a total of 57 subjects (16 elite male wrestlers, 21 water polo player and 20 sedentary subjects matched for age) were analyzed. Cardiopulmonary exercise testing (CPET) on a treadmill was used as the laboratory stress model; peak oxygen consumption (VO₂) was obtained during CPET. Plasma levels of adrenocorticotropic hormone (ACTH), cortisol, alpha-melanocyte stimulating hormone (alpha-MSH) and N-terminal-pro-B type natriuretic peptide (NT-pro-BNP) were measured by radioimmunometric, radioimmunoassay and immunoassay sandwich technique, respectively, together with cardiopulmonary measurements, 10 minutes pre-CPET and at the initiation of CPET. The response of diastolic blood pressure and heart rate was different between groups during stress anticipation (<i>p</i> = 0.019, 0.049, respectively), while systolic blood pressure, peak VO₂ and carbon-dioxide production responses were similar. ACTH and cortisol increased during the experimental condition, NT-pro-BNP decreased and alpha-MSH remained unchanged. All groups had similar hormonal responses during stress anticipation with the exception of the ACTH/cortisol ratio. In all three groups, ΔNT-pro-BNP during stress anticipation was the best independent predictor of peak VO₂ (B = 36.01, <i>r</i> = 0.37, <i>p</i> = 0.001). In conclusion, the type of chronic stress exposure influences the hemodynamic response during anticipation of physical stress and the path of hormonal stress axis activation. Stress hormones released during stress anticipation may hold predictive value for overall cardiopulmonary performance during the stress condition.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"14-21"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39812829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Chronic stress predicts post-traumatic stress disorder symptoms via executive function deficits among urban American Indian children.","authors":"Juyoung Kim,&nbsp;Longfeng Li,&nbsp;Kevin M Korous,&nbsp;Carlos Valiente,&nbsp;Monica Tsethlikai","doi":"10.1080/10253890.2021.2024164","DOIUrl":"https://doi.org/10.1080/10253890.2021.2024164","url":null,"abstract":"<p><p>Little is known about how chronic exposure to stress affects mental health among American Indian (AI) children. The current study aimed to fill this gap by exploring if hair cortisol concentration (HCC), an indicator of chronic stress, predicted post-traumatic stress disorder (PTSD) symptoms through deficits in executive function (EF) skills commonly referred to as inhibitory control, working memory, and cognitive flexibility. A total of 163 urban AI children between 8- and 15-years old participated in the study (92 girls, 56.4%; <i>M</i>_age = 11.19, <i>SD</i> = 1.98). Chronic stress was measured as the concentration of cortisol in children's hair. EF deficits and PTSD symptoms were reported by primary caregivers using the Behavior Rating Inventory of Executive Function and the Trauma Symptom Checklist for Young Children. The results demonstrated that higher HCC was indirectly associated with more PTSD symptoms through deficits in EF skills. Specifically, higher levels of HCC were related to more symptoms of PTSD arousal through impaired working memory, and more symptoms of PTSD avoidance and Intrusion through deficits in cognitive flexibility. The findings suggest interventions that reduce or buffer chronic stress, or that focus on improving EF skills, may promote not only cognitive development but also the mental health of AI children.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"97-104"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39940570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Habitual use of psychological coping strategies is associated with physiological stress responding during negative memory recollection in humans.","authors":"Kyle P Rawn,&nbsp;Peggy S Keller","doi":"10.1080/10253890.2021.2007372","DOIUrl":"https://doi.org/10.1080/10253890.2021.2007372","url":null,"abstract":"<p><p>Research has identified a variety of strategies people use to cope with stress and that the adaptiveness of various strategies depends on the context in which they are used. However, important questions remain about the role of physiological stress response systems in supporting, influencing, or changing from coping strategies. This study works toward addressing this gap by examining associations between skin conductance level (SCL) and habitual use of coping strategies. It was hypothesized that more use of problem-focused strategies would be associated with SCL trajectories that were more stable and decreased less steeply, with the opposite trend hypothesized for more use of emotion-focused strategies. Participants were 188 college students (78% female) who reported their use of 14 coping strategies. SCL was recorded during recall of a negative family memory from childhood for five minutes. Trajectories of SCL during the recall were estimated with multilevel modeling. Greater self-distraction, planning, active coping, use of emotional support, and coping flexibility were related to trajectories of SCL that decreased less steeply and were more stable. Problem-focused coping and coping flexibility are, therefore, related to reduced SCL reactivity and promoting these skills may benefit mental health.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"30-39"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39657566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Safe in my heart: resting heart rate variability longitudinally predicts emotion regulation, worry, and sense of safeness during COVID-19 lockdown.","authors":"Elena Makovac,&nbsp;Luca Carnevali,&nbsp;Sonia Medina,&nbsp;Andrea Sgoifo,&nbsp;Nicola Petrocchi,&nbsp;Cristina Ottaviani","doi":"10.1080/10253890.2021.1999408","DOIUrl":"https://doi.org/10.1080/10253890.2021.1999408","url":null,"abstract":"<p><p>Resting heart rate variability (HRV), a surrogate index of cardiac vagal modulation, is considered a putative biomarker of stress resilience as it reflects the ability to effectively regulate emotions in a changing environment. However, most studies are cross-sectional, precluding longitudinal inferences. The high degree of uncertainty and fear at a global level that characterizes the COVID-19 pandemic offers a unique opportunity to explore the utility of HRV measures as longitudinal predictors of stress resilience. This study examined whether resting measures of HRV prior to the COVID-19 outbreak (i.e. nearly 2 years before; Time 0) could predict emotion regulation strategies and daily affect in healthy adults during the May 2020 lockdown (Time 1). Moreover, we evaluated the association between HRV measures, emotion regulation strategies, subjective perception of COVID-19 risk, and self-reported depressive symptoms at Time 1. Higher resting HRV at Time 0 predicted a stronger engagement in more functional emotion regulation strategies, as well as of higher daily feelings of safeness and reduced daily worry at Time 1. Moreover, depressive symptoms negatively correlated with HRV and positively correlated with the subjective perception of COVID-19 risk at Time 1. Current data support the view that HRV might not only be a marker but also a precursor of resilience under stressful times.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"9-13"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39661589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A laboratory medical anamnesis interview elicits psychological and physiological arousal.","authors":"Sarah C Sturmbauer,&nbsp;Andreas R Schwerdtfeger,&nbsp;Simon Schmelzle,&nbsp;Nicolas Rohleder","doi":"10.1080/10253890.2021.2012145","DOIUrl":"https://doi.org/10.1080/10253890.2021.2012145","url":null,"abstract":"<p><p>Since medical communication can be perceived as stressful, the assessment of patients' physiological arousal and behavior during anamnesis interviews may lead to a better understanding of doctor-patient interactions. Therefore, the aim of this study was to test physiological arousal and word use in a laboratory anamnesis interview. In total, sixty-five participants with a mean age of 25.0 years were randomly assigned either to an experimental group (<i>n</i> = 35, 65.7% women) in which they underwent an anamnesis interview or to a control group (<i>n</i> = 30, 73.3% women). Physiological arousal was assessed by salivary cortisol, salivary alpha-amylase (sAA), heart rate (HR) and heart rate variability (HRV). Psychological arousal was assessed using the Positive and Negative Affect Schedule (PANAS). Anamnesis interviews were analyzed using the Linguistic Inquiry and Word Count text analysis tool (LIWC). Participants of the experimental group showed an increase of sAA, HR and negative affect (<i>p'</i>s ≤.0.05). Moreover, higher cortisol area under the curve with respect to ground (AUCg) was associated with lesser use of positive emotion words during the interview and subsequent higher negative affect (<i>p</i>'s <.05). These results indicate that talking about one's own and family's medical history in anamnesis interview induces physiological arousal. Our findings suggest that anamnesis interviews could not only induce higher negative affect, but also induce physiological arousal, underscoring the importance of good doctor-patient communication.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"57-66"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39746784","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of chronic stress on the PFC transcriptome: a bioinformatic meta-analysis of publicly available RNA-sequencing datasets.","authors":"Anand Gururajan","doi":"10.1080/10253890.2022.2111211","DOIUrl":"https://doi.org/10.1080/10253890.2022.2111211","url":null,"abstract":"<p><p>The prefrontal cortex (PFC) is one of several brain structures that are sensitive to chronic stress exposure. There have been several studies which have examined the effects on chronic stress, using various protocols such as chronic unpredictable stress and chronic social defeat stress, on the PFC transcriptome. In this report, a bioinformatic meta-analysis of publicly available RNA sequencing datasets (101 samples) from seven chronic stress studies was carried out to identify core PFC transcriptional signatures that underpin behavioral phenotypes including resilience and susceptibility. The results showed 160 differentially expressed genes in chronic stress mice compared to controls with significant enrichment in mechanisms associated with translation and localization of membrane-bound proteins with a putative effect on synaptic plasticity in glutamatergic neurons. Moreover, the meta-analysis revealed no differentially expressed genes in resilient mice but 144 in susceptible mice compared to controls, of which 44 were not identified in the individual studies. Enrichment analysis revealed that susceptibility genes were most affected in oligodendrocytes and linked to mechanisms which mediate biochemical, bidirectional communication between this cell-type and myelinated axons. These results provide new avenues for further research into the neurobiology and treatment of chronic stress-induced disorders.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"305-312"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40708167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The cortisol awakening response and the late positive potentials evoked by unpleasant emotional pictures in healthy adults.","authors":"Xia Shi,&nbsp;Xin Nie,&nbsp;Jianhui Wu","doi":"10.1080/10253890.2021.2008902","DOIUrl":"https://doi.org/10.1080/10253890.2021.2008902","url":null,"abstract":"<p><p>The cortisol awakening response (CAR) refers to a sharp rise in cortisol concentrations within the 45 min following morning awakening. Alterations in CAR have been associated with various internalizing symptoms and brain function. The current study aimed to investigate the association between CAR and neural activity in response to unpleasant emotional pictures. A total of 46 healthy adults (22.55 years ± 1.69) collected saliva samples at 0, 30, and 45 min post-awakening on two days to assess the CAR. In the afternoon after CAR measurement on the first day, electroencephalograms were recorded when the participants completed a passive viewing task. The results showed that a greater CAR was associated with a decreased late positive potential difference score between unpleasant and neutral stimuli. This finding indicates that a larger CAR may be associated with decreased attentional engagement to unpleasant emotional information in healthy adults.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"40-47"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39705342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of stress-related neural activity and baseline interleukin-6 plasma levels in healthy adults.","authors":"Johanna F Voges,&nbsp;Laura Müller-Pinzler,&nbsp;Miriam Neis,&nbsp;Finn Luebber,&nbsp;Tanja Lange,&nbsp;Jennifer E Hundt,&nbsp;Meike Kasten,&nbsp;Ulrike M Krämer,&nbsp;Sören Krach,&nbsp;Lena Rademacher","doi":"10.1080/10253890.2022.2094704","DOIUrl":"https://doi.org/10.1080/10253890.2022.2094704","url":null,"abstract":"<p><p>Several studies suggest a link between acute changes in inflammatory parameters due to an endotoxin or (psychological) stressor and the brain's stress response. The extent to which basal circulating levels of inflammatory markers are associated with the brain's stress response has been hardly investigated so far. In the present study, baseline plasma levels of the cytokine interleukin (IL)-6 were obtained and linked to neural markers of psychosocial stress using a modified version of the Montreal Imaging Stress Task in a sample of <i>N</i> = 65 healthy subjects (<i>N</i> = 39 female). Of three a-priori defined regions of interest - the amygdala, anterior insula, and anterior cingulate cortex - baseline IL-6 was significantly and negatively associated with stress-related neural activation in the right amygdala and left anterior insula. Our results suggest that baseline cytokines might be related to differences in the neural stress response and that this relationship could be inverse to that previously reported for induced acute changes in inflammation markers.</p>","PeriodicalId":141741,"journal":{"name":"Stress (Amsterdam, Netherlands)","volume":" ","pages":"267-275"},"PeriodicalIF":2.3,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40608454","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}