F. Prasser, J. Eicher, Raffael Bild, Helmut Spengler, K. Kuhn
{"title":"A Tool for Optimizing De-identified Health Data for Use in Statistical Classification","authors":"F. Prasser, J. Eicher, Raffael Bild, Helmut Spengler, K. Kuhn","doi":"10.1109/CBMS.2017.105","DOIUrl":"https://doi.org/10.1109/CBMS.2017.105","url":null,"abstract":"When individual-level health data is shared in biomedical research the privacy of patients and probands must be protected. This is typically achieved with methods of data de-identification, which transform data in such a way that formal guarantees about the degree of protection from re-identification can be provided. In the process it is important to minimize loss of information to ensure that the resulting data is useful. A typical use case is the creation of predictive models for knowledge discovery and decision support, e.g. to infer diagnoses or to predict outcomes of therapies. A variety of methods have been developed which can be used to build robust statistical classifiers from de-identified data. However, they have not been tuned for practical use and they have not been implemented into mature software tools. To bridge this gap, we have extended ARX, an open source anonymization tool for health data, with several new features. We have implemented a method for optimizing the suitability of de-identified data for building statistical classifiers and a method for assessing the performance of classifiers built from de-identified data. All methods are accessible via a comprehensive graphical user interface. We have used our implementation to create logistic regression models from a patient discharge dataset for predicting the costs of hospital stays. The results show that our approach enables the creation of privacy-preserving classifiers with optimal prediction accuracy.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"63 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127748943","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Cazzolato, L. C. Scabora, Alceu Ferraz Costa, Marcos Roberto Nesso Junior, Luis Fernando Milano Oliveira, D. S. Kaster, C. Traina, A. Traina
{"title":"BREATH: Heat Maps Assisting the Detection of Abnormal Lung Regions in CT Scans","authors":"M. Cazzolato, L. C. Scabora, Alceu Ferraz Costa, Marcos Roberto Nesso Junior, Luis Fernando Milano Oliveira, D. S. Kaster, C. Traina, A. Traina","doi":"10.1109/CBMS.2017.82","DOIUrl":"https://doi.org/10.1109/CBMS.2017.82","url":null,"abstract":"Computed Tomography (CT) scans are often employed to diagnose lung diseases, as abnormal tissue regions may indicate whether proper treatment is required. However, detecting specific regions containing abnormalities in a CT scan demands time and effort of specialists. Moreover, different parts of a single lung image may present both normal and abnormal characteristics, what makes inaccurate the classification of a single lung as healthy (normal) or not. In this paper we propose the BREATH method, capable of detecting abnormalities in lung tissue regions, highlighting them by means of a heat map visualization. The method starts by segmenting lung tissues using a superpixel-based approach, followed by the training of a statistical model to represent normal tissues and, finally, the generation of a heat map showing abnormal regions that require attention from the physicians. We validated our statistical model using a dataset with 246 lung CT scans, where 40 are healthy and the remaining present varying diseases. Experimental results show that BREATH is accurate for lung segmentation with F-Measure of up to 0.99. The statistical modeling of healthy and abnormal lung regions has shown almost no overlap, and the detection of superpixels containing abnormalities presented precision values higher than 86%, for all values of recall. These values support our claim that the heat map representation of BREATH for the abnormal detection can be used as an intuitive method to assist physicians during the diagnosis.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"98 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115797739","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Miro Schleicher, T. Ittermann, Uli Niemann, H. Völzke, M. Spiliopoulou
{"title":"ICE: Interactive Classification Rule Exploration on Epidemiological Data","authors":"Miro Schleicher, T. Ittermann, Uli Niemann, H. Völzke, M. Spiliopoulou","doi":"10.1109/CBMS.2017.127","DOIUrl":"https://doi.org/10.1109/CBMS.2017.127","url":null,"abstract":"Personalized medicine benefits from the identification of subpopulations that exhibit higher prevalence of a disease than the general population: such subpopulations can become the target of more intensive investigations to identify risk factors and to develop dedicated therapies. Classification rule discovery algorithms are an appropriate tool for discovering such subpopulations: they scale well, even for multi-dimensional data and deliver comprehensible patterns. However, they may generate hundreds of rules and thus call for exploration methods. In this study, we extend the tool Interactive Medical Miner for the discovery of classification rules, into the Interactive Classification rule Explorer ICE, which offers functionalities for rule exploration, grouping, rule visualization and statistics. We report on our first results for the classification of cohort data on goiter, a disorder of the thyroid gland.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"195 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124322932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Loizou, Christos Papacharalambous, Giorgos Samaras, E. Kyriacou, T. Kasparis, M. Pantziaris, E. Eracleous, C. Pattichis
{"title":"Brain Image and Lesions Registration and 3D Reconstruction in Dicom MRI Images","authors":"C. Loizou, Christos Papacharalambous, Giorgos Samaras, E. Kyriacou, T. Kasparis, M. Pantziaris, E. Eracleous, C. Pattichis","doi":"10.1109/CBMS.2017.53","DOIUrl":"https://doi.org/10.1109/CBMS.2017.53","url":null,"abstract":"During a human brain MRI acquisition the resulting image is formed out of 2D slices. The slices must then be aligned and reconstructed to provide a 3-dimensional (3D) visualization of the brain volume. We propose in this work, an integrated system for the register ion and 3D reconstruction of DICOM MRI images and lesions of the brain acquired from multiple sclerosis (MS) subjects at two different time intervals (time 0 (T0) and time 1 (T1)). The system facilitates the follow up of the MS disease development and will aid the doctor to accurately manage the follow up of the disease. It involves a 6-stage analysis (preprocessing, lesion segmentation, registration, 3D reconstruction, volume estimation and method evaluation), as well as module quantitative evaluation of the method. The system was evaluated based on one MRI phantom and one DICOM MRI image of the brain. The accuracy of the proposed registration and reconstruction (- / -) method was 78.5%/97.2% and 95.4%/95.8% for the phantom and the MRI images respectively. These preliminary results provide evidence that the proposed system could be applied in future in the clinical practice.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125251643","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comparing the Quality of Numeracy Assessment Methods in Healthcare","authors":"M. Omidbakhsh, O. Ormandjieva","doi":"10.1109/CBMS.2017.90","DOIUrl":"https://doi.org/10.1109/CBMS.2017.90","url":null,"abstract":"Numeracy skill level of patients has great influence on their preferences and priorities for the treatment options concerning their healthcare. There have been different methods for assessment of numeracy skill in healthcare domain. In our previous research we proposed a new Confidence-based Patient Numeracy Assessment (C-PNA) method. In this paper we compare it with other numeracy assessment methods in terms of newly proposed quality characteristics. The results reveal that our confidence-based numeracy assessment method outperforms the non-confidence assessment method in terms of objective and subjective quality characteristics of the newly proposed quality model.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115601318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
George Dimas, Dimitrios K. Iakovidis, G. Ciuti, A. Karargyris, Anastasios Koulaouzidis
{"title":"Visual Localization of Wireless Capsule Endoscopes Aided by Artificial Neural Networks","authors":"George Dimas, Dimitrios K. Iakovidis, G. Ciuti, A. Karargyris, Anastasios Koulaouzidis","doi":"10.1109/CBMS.2017.67","DOIUrl":"https://doi.org/10.1109/CBMS.2017.67","url":null,"abstract":"Various modalities are used for the examination of the gastrointestinal (GI) tract. One such modality is Wireless Capsule Endoscopy (WCE), a non-invasive technique which consists of a swallowable color camera that enables the detection of GI pathology with only minimal patient discomfort. Currently, tracking of the capsule position is estimated in the 3D abdominal space, using radio-frequency (RF) triangulation. The RF triangulation technique, however, does not provide sufficient information about the location of the capsule along the GI lumen, and consequently, the localization of any possible abnormality. Recently, we proposed a geometric visual odometry (VO) method for the localization of the capsule in the GI lumen. In this paper, we extend this state-of-art method by exploiting an artificial neural network (ANN) to augment the geometric method and achieve higher localization accuracy. The results of this novel approach are validated with an in-vitro experiment that provides ground truth information about the location of the capsule. The mean absolute error obtained, for a distance of 19.6cm, is 0.79±0.51cm.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"32 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121704566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. V. Aranha, Leonardo Souza Silva, M. Chaim, Fátima L. S. Nunes
{"title":"Using Affective Computing to Automatically Adapt Serious Games for Rehabilitation","authors":"R. V. Aranha, Leonardo Souza Silva, M. Chaim, Fátima L. S. Nunes","doi":"10.1109/CBMS.2017.89","DOIUrl":"https://doi.org/10.1109/CBMS.2017.89","url":null,"abstract":"Although many studies investigate the automatic adaptation in serious games with the goal to improve the users motivation, the majority of Affective Computing approaches requires a high development cost and usually does not consider the intervention of health professionals in adapting the game. This paper describes an approach to enable affective adaptation in serious games for motor rehabilitation with physiotherapists aid. Our approach consists of the definition and implementation of a framework. Its architecture reduces the development cost of a game with affective adaptation whilist enabling physiotherapists to configure adaptations in it according to patients profile. The results of an experiment with physiotherapists show that the system presents a high level of acceptance.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"60 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122580192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H. Kondylakis, A. Bucur, F. Dong, C. Renzi, A. Manfrinati, N. Graf, S. Hoffman, L. Koumakis, G. Pravettoni, K. Marias, M. Tsiknakis, Stephan Kiefer
{"title":"iManageCancer: Developing a Platform for Empowering Patients and Strengthening Self-Management in Cancer Diseases","authors":"H. Kondylakis, A. Bucur, F. Dong, C. Renzi, A. Manfrinati, N. Graf, S. Hoffman, L. Koumakis, G. Pravettoni, K. Marias, M. Tsiknakis, Stephan Kiefer","doi":"10.1109/CBMS.2017.62","DOIUrl":"https://doi.org/10.1109/CBMS.2017.62","url":null,"abstract":"Cancer research has led to more cancer patients being cured, and many more enabled to live with their cancer. As such, some cancers are now considered a chronic disease, where patients and their families face the challenge to take an active role in their own care and in some cases in their treatment. To this direction the iManageCancer project aims to provide a cancer specific self-management platform designed according to the needs of patient groups while focusing, in parallel, on the wellbeing of the cancer patient. In this paper, we present the use-case requirements collected using a survey, a workshop and the analysis of three white papers and then we explain the corresponding system architecture. We describe in detail the main technological components of the designed platform, show the current status of development and we discuss further directions of research.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123317178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Michael Zimoch, R. Pryss, T. Probst, W. Schlee, M. Reichert
{"title":"Towards a Conceptual Framework Fostering Process Comprehension in Healthcare","authors":"Michael Zimoch, R. Pryss, T. Probst, W. Schlee, M. Reichert","doi":"10.1109/CBMS.2017.70","DOIUrl":"https://doi.org/10.1109/CBMS.2017.70","url":null,"abstract":"Despite the widespread use of process models in healthcare organizations, there are many unresolved issues regarding the reading and comprehension of these models by domain experts. This is aggravated by the fact that there exists a plethora of process modeling languages for the graphical documentation of processes, which are often not used consistently for various reasons. Hence, the identification of those factors fostering the comprehension of process models becomes crucial. We have developed a conceptual framework incorporating measurements and theories from cognitive neuroscience and psychology to unravel factors fostering the comprehension of process models within organizations. We believe that a better comprehension of process models will enhance the support of healthcare processes significantly.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124873529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Application of Neuromuscular Electrical Stimulation (NMES) Technologies in Cancer Care","authors":"Dominic O’Connor, B. Caulfield","doi":"10.1109/CBMS.2017.95","DOIUrl":"https://doi.org/10.1109/CBMS.2017.95","url":null,"abstract":"Despite the increase in long term cancer survivors, successful treatment is associated with significant sequelae. As a result, participation in voluntary exercise becomes difficult highlighting the need for pragmatic alternatives. Neuromuscular electrical stimulation (NMES) has been shown as effective in pathological conditions for improving muscle strength. However, its use in cancer care is sparse and has provided equivocal results. This paper outlines a proposed approach to the design, development, evaluation and implementation of NMES technology into cancer pathways. The proposed process comprises four stages; 1) understanding the clinical challenges faced by survivors, 2) identify the benefits of NMES in this cohort, 3) the design of the NMES protocol, 4) the evaluation of the protocol in cancer survivors, and 5) the implementation of the protocol into cancer care pathways. In this paper, we outline advancements in NMES technology which may be utilised to simultaneously improve indices of cardiovascular exercise capacity and skeletal muscle strength.","PeriodicalId":141105,"journal":{"name":"2017 IEEE 30th International Symposium on Computer-Based Medical Systems (CBMS)","volume":"190 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126039904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}