International Journal of Medical Science And Diagnosis Research最新文献

{"title":"The Relationship between Sickle Cell Disease and Pulmonary Hypertension in Adults","authors":"Mariam Alabdo, Firas Hussein, Basem Marouf","doi":"10.14445/23939117/ijms-v9i2p101","DOIUrl":"https://doi.org/10.14445/23939117/ijms-v9i2p101","url":null,"abstract":"","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75260316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analytical Study of Thrombocytopenia in Pregnant Women in Tishreen University Hospital (Causes, Complications, Management)","authors":"A. Marouf, F. Hussein, Louai Hasan","doi":"10.14445/23939117/ijms-v9i1p102","DOIUrl":"https://doi.org/10.14445/23939117/ijms-v9i1p102","url":null,"abstract":"","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78347284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Flow Cytometry based 'Acute Myeloid Leukemia Maturity Score' is a Novel Marker for Predicting Relapse in Acute Myeloid Leukemia: A Prospective Observational Study","authors":"P. Mishra, Seema Tyagi, Preeti Tripathi, Rahul Sharma, H P Pati, Manoranjan Mahapatra","doi":"10.32553/ijmsdr.v6i2.910","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i2.910","url":null,"abstract":"Objectives:  A novel flow cytometric ‘AML Maturity Score (AMS)’ classifying patients into AML-immature (AML-im) and AML-mature (AML-ma) based on CD34, CD117 and Tdt expression on blasts correlated with induction remission, relapse free survival and overall survival in previous studies. We aimed to study the correlation between AMS and ELN risk group and outcomes- induction remission (IR), time to remission (TTR) and relapse. \u0000Material and Methods:  This was a combined prospective and retrospective study of 104 AML patients over 30 months. Flow cytometry based quantitative expression of CD34, TdT and CD117 on blasts was used for calculating AMS and additional tube for CD34+CD38-CD123+ cells was put at diagnosis in 47 patients prospectively studied. The patients received 1-2 cycles of standard induction (3+7) comprising Daunorubicin (60mg/m2/day for 3 days) and Cytarabine (continuous infusion 100mg/m2/day for 7 days). Data was collected on the clinical and laboratory parameters, cytogenetics and molecular profile of these patients who were followed up for IR, TTR and relapse. \u0000Results: Of 104 patients, AML-im were 86.6% (90/104) and AML-ma were 13.4% (14/104). Patients were classified as – favorable risk (28.8%), intermediate risk (50%) and adverse risk (21.1%) on the basis of ELN 2017. Of 104 patients, 74 attained IR and of 65 patients followed up over mean period of 18 months, 27 relapsed. The mean AMS was significantly more in patients who attained IR (p=0.003). On classifying patients as AML-im and AML-ma, TTR (p=0.000) and relapses (p=0.043) were significantly higher in AML-im group. \u0000Conclusion:  AMS is a novel flow cytometry based potential marker for predicting relapses in AML patients.","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81580142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"EFFECT OF MATERNAL BODY MASS INDEX ON THE MODE OF DELIVERY AND NEONATAL OUTCOME: A TERTIARY CARE HOSPITAL BASED STUDY IN SOLAN, HIMACHAL PRADESH.","authors":"S. Aggarwal, M. Behal, N. Singal, S. Minhas, Sheetal Dagar","doi":"10.32553/ijmsdr.v6i2.912","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i2.912","url":null,"abstract":"INTRODUCTION: Obesity is a global health problem characterised as a pandemic issue by the World Health Organization (WHO), with a higher prevalence in females than males. During pregnancy, it is considered a high-risk state because it is associated with maternal complications like preeclampsia, gestational diabetes, obstetric interventions like caesarean delivery, postpartum haemorrhage; and fetal complications like macrosomia, poor apgar scores. BMI is a commonly used indicator which can be used to classify subjects on the basis of weight.AIM: This study aims to find the prevalence of normal weight, overweight and obese pregnant women defined by body mass index (BMI) according to the WHO classification and to study the associations between maternal BMI, the mode of delivery and neonatal outcome.MATERIAL AND METHODS: 200 pregnant women admitted for delivery in the department of Obstetrics & Gynaecology were studied, height and weight were recorded from reliable antenatal records (recorded within two months of gestation). The Body Mass Index was calculated and patients were divided into four categories: Category I: underweight; Category II: normal BMI; Category III: Overweight; Category IV: Obese. The feto-maternal outcomes were studied.RESULTS: On evaluation of 200 nulliparous antenatal women with singleton term gestation, 1.5% were underweight, 33% had normal BMI, 56% were overweight and 9.5% were obese. The prolongation of labour was seen in subjects with BMI more than 25 kg/m2. Overweight patients had more instrumental deliveries and obese patients had a higher tendency for prolonged labour and caesarean deliveries. Neonatal outcomes were poor for obese and overweight patients as compared to normal BMI because more neonates required resuscitation at birth, had low Apgar scores and were small for gestational age. Maternal complications like Hypothyroidism, preeclampsia and gestational diabetes occurred more commonly in the obese category.CONCLUSION: In our institution, majority of patients were found to be overweight. Adverse perinatal outcomes were seen more often in the obese patients. Hence, obesity must be identified as a risk factor for adverse pregnancy outcomes.","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77605678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Gentamicin Loaded Collagen on Compound Fracture Internal Fixation","authors":"Nitin Sanadhya","doi":"10.32553/ijmsdr.v6i2.919","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i2.919","url":null,"abstract":"Introduction:  In the today’s world with faster ways of transportation  high velocity accidents and  the compound fracture are increasing day by day producing a challenge preventing post operative  wound infections after internal fixation of  fracture. \u0000Materials and Methods: 50 patients of compound fractures were included in the study and were randomly divided in 2 groups of 25 each . Both the groups undergone internal fixation with stainless  steel implant and one group wound is closed with gentamicin loaded collagen in it and other group without it \u0000Method: In both the groups same process of  and lavage  is used and  fractures were  fixed internally fixed . A group has 25 patients in which after internal fixation the gentamicin loaded collagen is placed  inside and in B group after internal fixation  wound is closed without gentamicin loaded collagen. \u0000Results: In  group A where Gentamicin loaded collagen was placed wound infection was there in 2 patients . In  Group B were no gentamicin loaded collagen was used  9 patietns has infections. P value  0.0275 \u0000Discussion: After surgery wound is assessed for post operative infection on  2 nd post op day  14 day  at 4 weeks    6 weeks   3 months  and 6 months \u0000Conclusion: The Author  believe  that  use of gentamicin loaded collagen significantly reducing the chance of infection in  compound fractures surgeries. \u0000Keywords: compound fracture, gentamicin loaded collagen, post operative infection","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73697285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"To Study the Prevalence of Vitamin D Deficiency in Third Trimester and Feto-Maternal Outcome.","authors":"Sheetal Dagar, Monika Gupta, Monika Jindal, S. Minhas, S. Aggarwal","doi":"10.32553/ijmsdr.v6i2.913","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i2.913","url":null,"abstract":"Aim: To estimate the prevalence of vitamin D deficiency in third trimester and itscorrelation with feto-maternal outcome \u0000Material and Methods: Present study was conducted 200 pregnant women who were admitted to the labor room in the third trimester in the department of Obstetrics & Gynecology of Maharishi Markandeshwar Medical College and Hospital, Solan (H.P.) for delivery after fulfilling the inclusion & exclusion criteria. Detailed history including complete demographic information, past medical history, dietary history, previous menstrual & obstetric history, any antenatal complications. Delivery details including mode of delivery, birth weight and APGAR scores were recorded on the proforma. Serum vitamin D was estimated fromthe maternal blood sample. Vitamin D deficiency was defined as 25(OH) D levels in blood less than 20 ng/ml, and insufficiency of vitamin D was defined as 25(OH) D levels between 20-30 ng/ml.Results: In this study, there was a high prevalence of vitamin D deficiency (93.5%) in the pregnant women though there was no significant difference in socio-demographic factors in the deficient and non-deficient group. Present study showed that the proportion of vitamin D deficient pregnant women having maternal complications and NICU admission was statistically significant as compared to the non-deficient group (p=0.0109) and (p=0.0384) respectively. \u0000Conclusion: Maternal complications, increased cesarean section rate and NICU admission weremore associated with hypovitaminosis D but any causal relationship between vitaminD deficiency and pregnancy complications was not found in this study design. Wepropose that vitamin D supplementation is simple and economical, and hence weshould incorporate vitamin D testing, increase its awareness and treat its deficiency inadolescence, pre-conceptional period or 1st trimester to avoid maternal complicationsand poor fetal outcome. \u0000Keywords: Vitamin D Deficiency, Third trimester, Fetal outcome, Maternal outcomex","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80715345","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"COVID 19 & its Different Colours- An Autobiographical¸Case Report of a Physician Suffering Twice with COVID Atypical Symptoms Despite Vaccinated.","authors":"Manuj Kumar Sarkar, U. Rakesh, S. Dey, B. Munshi","doi":"10.32553/ijmsdr.v6i2.918","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i2.918","url":null,"abstract":"COVID 19 caused by severe acute respiratory syndrome corona virus 2 (SARS CoV2). Initial infection started from China in December 2019. It became pandemic and till date it has infected 399 million people all over the world. First wave was associated with more panic situation and it has impacted mental health globally. As time passed and with subsequent waves, we have learnt to deal with the stress caused by COVID 19. I am presenting my case of suffering from COVID 19 twice despite vaccinated and its psychological impact on mental status. ","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85363577","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Isolated Miliary Tuberculosis of Brain in an Immuno-Competent Patient, Presenting as Cerebellar Ataxia","authors":"Adhip Arora","doi":"10.32553/ijmsdr.v6i2.916","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i2.916","url":null,"abstract":"We are reporting an unusual case of a 26-year-old immunocompetent patient of miliary tuberculosis of cerebellum with meningitis and lung involvement, presenting with ataxia without any evidence of systemic inflammation. Since, prognosis depends on correct diagnosis and timely treatment, recognition and prompt diagnosis are important for overall outcome. ","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75631911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Umbilical Cord Coiling Index Sonographic Evaluation in its Relationship with Perinatal Outcome and Late Second Trimester","authors":"Balameenakshi, G. Yuvabalakumaran","doi":"10.32553/ijmsdr.v6i1.909","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i1.909","url":null,"abstract":"Objectives: To assess the relationship between perinatal results along with umbilical cord coiling index derived from sonographer solutions. \u0000Study Design: This predictive research was executed in the OBG department of radiology at Vinayaka missions Kirupananda Variyar medical college and hospital of Medical Sciences, Salem, India from April, 2021 to September, 2021. Of the 60 patients included in the study, single pregnancies with direct vaginal / LSCS babies, regardless of equality, with active delivery from the second trimester to final pregnancy. From the results of the ultrasound, the \"umbilical cord coiling index\" was correlated and calculated with different perinatal criteria such as equivalence, gestational hypertension (PIH), gestational diabetes (GD) and l gestational age (in weeks), Delivery method and Apgar score.  Fisher tests and Chi-squared were assist to determine the importance of the parameter findings. \u0000Results: The current results of the ultrasound evaluation show that the UCI provides a significant correlation with hypocrite coils (UCI> 90%), babies PIH (p-value <0.05), and GDM (p-value 0.044) Hypocoiled (UCI<10%) and Hypercoiled cords (p <0.05) were significantly related to the Apgar score (p less than 0.05). \u0000Conclusion: hypercoiled Coils or UCI> 90% is associated with IUGR and is part of primary perinatal results such as PIH and GDM. Both hypocoiled and hypercoied cords, and UCI <10%, linked to the Apgar score for the perinatal results, thus showing a greater correlation with the UCI index. \u0000Keywords: Hypercoiling umbilical cord, Umbilical cord coiling index, Hypocoiling umbilical cord \u0000 ","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83884411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Microflora Responsible for Failure of RCT : A Review","authors":"Anil K. Tomer, Nivedita Saini, Shivangi Jain, G. Sabharwal, Ayan Guin","doi":"10.32553/ijmsdr.v6i1.908","DOIUrl":"https://doi.org/10.32553/ijmsdr.v6i1.908","url":null,"abstract":"Endodontic treatment failure can be caused by a variety of factors, including bacterial persistence, improperly cleaned and obturated root canals, faulty coronal seal (leakage), and untreated canals (missed canals). The presence of bacteria such as Enterococcus (E.) faecalis inside the root canal system is the most common cause of endodontic failure. These bacteria are more resistant to disinfectants, resulting in an infection that persists intra-radicularly or extra-radicularly. Many other microorganism are also responsible for failure of root canal treatment, resulting in endodontic flare-up . \u0000This review article will discuss about the causes of failure of root canal treatment ,pathogenesis and strategies by which microbes persist in root canal, method of eradication of such microorganism and management of such cases. \u0000Keywords: Enterococcus, Enterococcus","PeriodicalId":14075,"journal":{"name":"International Journal of Medical Science And Diagnosis Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83722173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}