Role of Gentamicin Loaded Collagen on Compound Fracture Internal Fixation

Abstract

Introduction:  In the today’s world with faster ways of transportation  high velocity accidents and  the compound fracture are increasing day by day producing a challenge preventing post operative  wound infections after internal fixation of  fracture. Materials and Methods: 50 patients of compound fractures were included in the study and were randomly divided in 2 groups of 25 each . Both the groups undergone internal fixation with stainless  steel implant and one group wound is closed with gentamicin loaded collagen in it and other group without it Method: In both the groups same process of  and lavage  is used and  fractures were  fixed internally fixed . A group has 25 patients in which after internal fixation the gentamicin loaded collagen is placed  inside and in B group after internal fixation  wound is closed without gentamicin loaded collagen. Results: In  group A where Gentamicin loaded collagen was placed wound infection was there in 2 patients . In  Group B were no gentamicin loaded collagen was used  9 patietns has infections. P value  0.0275 Discussion: After surgery wound is assessed for post operative infection on  2 nd post op day  14 day  at 4 weeks    6 weeks   3 months  and 6 months Conclusion: The Author  believe  that  use of gentamicin loaded collagen significantly reducing the chance of infection in  compound fractures surgeries. Keywords: compound fracture, gentamicin loaded collagen, post operative infection