Mohammed Hamdan, Mohammad Ghassab Deameh, Amged Sadeq
{"title":"Response to Comment on: Meeting the growing demand: an operational blueprint for a 1500-case-per-year penile implant center of excellence.","authors":"Mohammed Hamdan, Mohammad Ghassab Deameh, Amged Sadeq","doi":"10.1038/s41443-026-01328-2","DOIUrl":"https://doi.org/10.1038/s41443-026-01328-2","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148446308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Douglas Schneider, Charles A Loeb, Mitchell O'Leary, Jeanie Nguyen, Eliad Amini, R Matthew Coward, Muhammed A M Hammad, Lawrence C Jenkins, Faysal A Yafi
{"title":"Assessment of work-related musculoskeletal pain in urologic microsurgeons.","authors":"Douglas Schneider, Charles A Loeb, Mitchell O'Leary, Jeanie Nguyen, Eliad Amini, R Matthew Coward, Muhammed A M Hammad, Lawrence C Jenkins, Faysal A Yafi","doi":"10.1038/s41443-026-01324-6","DOIUrl":"https://doi.org/10.1038/s41443-026-01324-6","url":null,"abstract":"<p><p>Work-related musculoskeletal disorders are common among surgeons, but data among urologic microsurgeons are limited. We conducted a 24-item anonymous online survey distributed via email to approximately 6000 urologists between June and July 2021, assessing demographics, operative volume, exercise patterns, ergonomic practices, and musculoskeletal disorders' symptoms using a modified Nordic Musculoskeletal Questionnaire. Fifty surgeons responded, response rate: 0.8% (50/6000). Mean age was 48.5 ± 12.4 years and body mass index 26.4 ± 3.1 kg/m². Past-year musculoskeletal disorders' symptoms were reported by 42/50 (84.0%) and weekly symptoms by 30/50 (60.0%). No clear differences were observed between exercise frequency, operative volume, or years in practice and musculoskeletal disorders' prevalence based on descriptive comparisons. Operating posture was associated with weekly symptoms: 8/20 (40.0%) of surgeons operating seated reported weekly symptoms versus 22/30 (73.3%) operating standing (p = 0.038). Weekly low back symptoms were reported by 1/20 (5.0%) seated versus 9/30 (30.0%) standing. Musculoskeletal disorders are highly prevalent among urologic microsurgeons, and seated operative posture may be associated with reduced symptom burden.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148446192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bogdan Toia, Amna Butt, Rachel Barratt, Anthony O Noah, Mahreen H Pakzad, Richard P Nobrega, Jeremy L Ockrim, Helena C M Gresty, Tamsin J Greenwell
{"title":"The developing field of meshology - what is new in the management of mesh complications in female incontinence and prolapse - a systematic review of outcomes.","authors":"Bogdan Toia, Amna Butt, Rachel Barratt, Anthony O Noah, Mahreen H Pakzad, Richard P Nobrega, Jeremy L Ockrim, Helena C M Gresty, Tamsin J Greenwell","doi":"10.1038/s41443-026-01316-6","DOIUrl":"https://doi.org/10.1038/s41443-026-01316-6","url":null,"abstract":"<p><p>Women having mesh procedures may require revision surgery in the long term due to complications. In the past decade, the field has evolved, moving towards specialist mesh centres. This systematic review analyses indications for treatment, whether complete mesh removal was achieved and treatment outcomes for delayed mesh complications. Fifty-six studies involving 4480 patients were identified from 2015 to 2025, to our knowledge, making this the largest systematic review of mesh complications in the modern era. Pain is the most common reason for seeking treatment for mesh complications and is present in up to 49-68% of women. Isolated surgical treatment for pain in the absence of anatomical abnormalities has poorer outcomes and often requires a holistic approach with specialist pain input. Asymptomatic vaginal exposure of under 1 cm can be treated with topical oestrogen with excellent success rates in selected patients. Endoscopic treatment for urethral extrusion has a 3% risk of urethrovaginal fistula. The risk of de novo incontinence is higher when the sub-urethral component of the mesh is removed compared to mesh arms (odds ratio 10.7). In large series, 15.6% of patients stayed in hospital for over 2 days after mesh removal, with a 2.8-13.7% incidence of >Clavien 3 complications. Robotic mesh removal surgery is an emerging approach and may play an important role, particularly when additional procedures are required, such as ureteric reconstruction and colposuspension.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Older age and low testosterone levels are independently associated with kidney stone prevalence in men: results from a large cross-sectional study.","authors":"Yunus Kayali, Fatih Bicaklioglu, Bilal Eryildirim","doi":"10.1038/s41443-026-01326-4","DOIUrl":"https://doi.org/10.1038/s41443-026-01326-4","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148436447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comment on: Reservoir placement and surgical considerations: a narrative review.","authors":"Helene De Bruyn, Koenraad Van Renterghem","doi":"10.1038/s41443-026-01284-x","DOIUrl":"https://doi.org/10.1038/s41443-026-01284-x","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148421070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohammed Hamdan, Mohammad Ghassab Deameh, Amged Sadeq, Yazeed Alghabban, Ghassan Talahmeh
{"title":"Outcomes of the Hamdan Extrainguinal Sub-Oblique (HESO) technique for reservoir placement in inflatable penile prosthesis implantation.","authors":"Mohammed Hamdan, Mohammad Ghassab Deameh, Amged Sadeq, Yazeed Alghabban, Ghassan Talahmeh","doi":"10.1038/s41443-026-01322-8","DOIUrl":"10.1038/s41443-026-01322-8","url":null,"abstract":"<p><p>Inflatable penile prosthesis (IPP) implantation is the standard treatment for refractory erectile dysfunction, but traditional reservoir placement in the space of Retzius risks injury. Ectopic and submuscular alternatives were developed to mitigate these potential complications. We evaluated the safety, feasibility, and outcomes of the Hamdan Extrainguinal Sub-Oblique technique, which uses direct visualization to avoid the space of Retzius. In this retrospective single-center study, we analyzed 186 consecutive patients who underwent primary IPP implantation using the Hamdan Extrainguinal Sub-Oblique technique between February 2025 and June 2025. All reservoirs were placed via a single penoscrotal incision into the extrainguinal sub-oblique space. Demographic data, comorbidities (including glycated hemoglobin), and perioperative outcomes were recorded. The median age was 56 (IQR 11) years, and the median body mass index was 28.7(5.7) kg/m². Comorbidities included diabetes (62.9%), hypertension (39.8%), dyslipidemia (28.5%), and ischemic heart disease or heart failure (21.0%). Notably, there were no intraoperative or postoperative reservoir-related complications during a short-term follow-up period of nine months. General complications were rare, consisting of 1 infection (0.5%) and 1 mechanical failure (0.5%). The Hamdan Extrainguinal Sub-Oblique technique appears to be a safe and anatomically controlled option for reservoir placement in the short term. By providing direct visualization and avoiding the space of Retzius, it may reduce the risk of visceral or vascular injury in selected patients.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148411842","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jarrett Noakes, Anthony Soler, Marshall Daffner, Alexander K Bishop, James T Burns, Syed Sarwar, Tate Valerio, Lucas Biondi, Rosstin Afsahi
{"title":"Selective serotonin reuptake inhibitors, erectile dysfunction, and the changing landscape of male sexual health.","authors":"Jarrett Noakes, Anthony Soler, Marshall Daffner, Alexander K Bishop, James T Burns, Syed Sarwar, Tate Valerio, Lucas Biondi, Rosstin Afsahi","doi":"10.1038/s41443-026-01323-7","DOIUrl":"https://doi.org/10.1038/s41443-026-01323-7","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148411755","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jarrett Noakes, Marshall Daffner, James T Burns, Alexander K Bishop, Tate Valerio, Lucas Biondi, Syed Sarwar, Rosstin Afsahi
{"title":"Response to comment on: GLP-1 receptor agonists and male sexual health: translating cardiometabolic benefits into erectile outcomes.","authors":"Jarrett Noakes, Marshall Daffner, James T Burns, Alexander K Bishop, Tate Valerio, Lucas Biondi, Syed Sarwar, Rosstin Afsahi","doi":"10.1038/s41443-026-01319-3","DOIUrl":"https://doi.org/10.1038/s41443-026-01319-3","url":null,"abstract":"","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Adham AbdelKader, Mohammed A Abdel-Rassoul, Galal El Shorbagy, Nadia Mohammed Hassan Madany, Hesham Torad
{"title":"Preoperative penoscrotal swab microbiology and postoperative infection concordance in malleable penile prosthesis surgery: A prospective randomized study of skin antisepsis.","authors":"Adham AbdelKader, Mohammed A Abdel-Rassoul, Galal El Shorbagy, Nadia Mohammed Hassan Madany, Hesham Torad","doi":"10.1038/s41443-026-01317-5","DOIUrl":"https://doi.org/10.1038/s41443-026-01317-5","url":null,"abstract":"<p><p>Surgical site infection (SSI) remains a serious complication of penile prosthesis implantation despite established preventive strategies. This prospective single-center randomized clinical study evaluated the clinical relevance of pre-antisepsis penoscrotal skin swabbing in men undergoing malleable penile prosthesis implantation by assessing organism-level concordance, defined as species-level matching between preoperative penoscrotal swab isolates and postoperative infection-site cultures in patients who developed SSI, based on routine phenotypic microbiological identification. A secondary objective was to compare chlorhexidine gluconate (CHG) and povidone-iodine (PVI) with respect to downstream postoperative outcomes. Between October 2023 and February 2024, 135 men undergoing malleable penile prosthesis implantation at a single tertiary referral center were randomized 1:1 using a computer-generated block randomization sequence to CHG (n = 69; 2% chlorhexidine in 70% alcohol) or PVI (n = 66; 10% povidone-iodine). Preoperative penoscrotal swabs were obtained before surgical skin antisepsis, and all patients completed standardized 12-month follow-up. SSI occurred in 15/135 patients (11.1%). Organism-level concordance between preoperative swab isolates and postoperative infection-site cultures was observed in 11/15 infected patients (73.3%; 95% confidence interval, 45.0-92.2%). Staphylococcus epidermidis was the most frequent concordant organism, with matching preoperative and postoperative isolates in 7/9 postoperative S. epidermidis infections (77.8%; p = 0.02). Overall SSI rates did not differ significantly between CHG and PVI groups (8.7% vs 13.6%, p = 0.42). However, compared with CHG, the PVI group showed earlier infection onset (4 ± 1 vs 6 ± 2 days, p = 0.03), higher postoperative bacterial colony counts (3.8 × 10⁵ ± 0.7 × 10⁵ vs 1.8 × 10⁵ ± 0.4 × 10⁵ CFU/mL, p = 0.01), and longer epithelialization time (10.4 ± 2.1 vs 9.2 ± 1.8 days, p = 0.03). These findings suggest that preoperative penoscrotal swabbing may provide clinically relevant microbiological information in higher-risk malleable penile prosthesis candidates, while CHG-based antisepsis may enhance bacterial suppression and wound healing.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Karl H Pang, King Sum Tong, Asif Muneer, Hussain M Alnajjar
{"title":"The association between obstructive sleep apnoea and erectile dysfunction: a systematic review and meta-analysis.","authors":"Karl H Pang, King Sum Tong, Asif Muneer, Hussain M Alnajjar","doi":"10.1038/s41443-026-01315-7","DOIUrl":"10.1038/s41443-026-01315-7","url":null,"abstract":"<p><p>While a link between obstructive sleep apnoea and erectile dysfunction is recognised, the correlation between their respective severities remains inadequately quantified. This systematic review and meta-analysis aimed to determine the correlation between markers of obstructive sleep apnoea and erectile dysfunction. In accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines, a systematic search was performed on PubMed, Embase, and Scopus for studies reporting correlations between the apnoea-hypopnea index or minimum oxygen saturation and validated versions of the International Index of Erectile Function (IIEF-5, IIEF-15, and IIEF-EF) scores. Eight studies met the pre-specified population, exposure, comparator, outcome, and study-design (PECOS) criteria. Meta-analysis of seven studies, with a pooled population of 594 patients, revealed a significant, moderate negative correlation between apnoea-hypopnoea index and International Index of Erectile Function scores (pooled Fisher's Z = - 0.43 ; 95% CI: -0.66 to -0.19). An analysis of three studies, comprising a pooled population of 513 patients, demonstrated a significant positive correlation between minimum oxygen saturation and International Index of Erectile Function scores (pooled Fisher's Z = 0.36 ; 95% CI: 0.04 to 0.69). Secondary findings highlighted a high prevalence of erectile dysfunction in patients with obstructive sleep apnoea, ranging from 59.0% to 69.0% across studied populations. Age was a significant confounding factor, and continuous Positive Airway Pressure was associated with reported improvements in erectile function in the included studies, although the magnitude of improvement varied according to the International Index of Erectile Function instrument used. These findings underscore the importance of screening for obstructive sleep apnoea in men presenting with erectile dysfunction, while recognizing that the pooled estimates are limited by high heterogeneity and variation in erectile-function instruments.</p>","PeriodicalId":14068,"journal":{"name":"International Journal of Impotence Research","volume":" ","pages":""},"PeriodicalIF":2.5,"publicationDate":"2026-07-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148396187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}